A few more non-Mendelian situations… For some traits, sex matters Sex Linked Traits • Traits located on sex chromosomes • Usually caused by recessive genes • Appear more commonly in males (only one X) – If recessive, females must carry trait on both XXs – Females with one copy are carriers • Males receive all X-linked traits from their mothers • Ex. Color blindness & hemophilia (abnormal blood clotting) Sex-Limited Traits • Generally found on autosomes • Only expressed in phenotype of one gender • Ex. Barred coloring in chickens normally is visible only in the roosters; Milk production in humans (females only) Sex-Influenced Traits • Traits located on autosomes • Genes are expressed differently for XX vs. XY • Ex. Early balding (influenced by testosterone) – Heterozygous men (Bb) lose their hair; Bb women do not. – Homozygous men or women (bb) become bald. – The trait is dominant in men, recessive in women. • Ex. Singing voice – same allele combo produces a high soprano female and low bass male Practice Problems • Cross a carrier female (for hemophilia) with a normal male. Of all their offspring, what is the probability they will produce a hemophiliac son? (H = normal blood, h = hemophilia) XH Xh XH XHXH XHXh Y XHY XhY