Medical Sciences Proof of Principle (MSc PoP) Program
Proposal Questions
PROGRAM OVERVIEW AND APPLICATION SUBMISSION INSTRUCTIONS
PROJECT REVIEW & TIMELINE
Please complete all the information in the Application Form ensuring:
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The proposal’s font and format are maintained
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The proposal is submitted via the OCE on-line application system and uploaded as an attachment (Word or
PDF format accepted). To set up an account for the OCE on-line application system contact ApplicationSupport@oce-ontario.org. If you have an account use your existing username and password to access the
application module.
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For MaRS Innovation Member Institutions the program is brought to you in partnership between OCE and MaRS
Innovation. Applications will be submitted to Jackie Terry, Program Administrator at
jterry@marsinnovation.com. MaRS Innovation will formally submit applications on behalf of their member
institutions and the start-up companies through OCE's online application system.
APPLICATION SUBMISSION CHECKLIST
Use the following list to ensure the necessary documentation is provided to OCE for a complete submission
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Application Information (Contact information and project title and Company Profile)
Public Release Classification
 Summary of Proposal for Public Release
 Project Category
 HQP Information
 Project Contacts
 Proposal
i. Proposal Questions uploaded as an attachment in this profile (NOTE: The Instruction page is to
be removed prior to uploading to the on-line system).
Project Plan and Budget
a. Milestones (Activities)
b. Project Finance (Budget and justification)
c. Attachment Checklist (supporting documentation to be uploaded)
i. Resumes/CVs or LinkedIn Profiles of key individuals connected to the project.
ii. Commitment letter, which includes the amount of cash contributions, terms of providing the
cash contributions and when the cash contributions will be provided to the project if approved
for funding through the program (the letter should be provided on letterhead).
Upon completion of the Application form please submit directly via the OCE on-line application system by the
Application Submission Deadlines.
Note – you will receive an auto-confirmation of receipt by the system within 24 hours of submission. If you do not
receive confirmation of receipt within this time, please contact the Application Support Team at applicationsupport@oce-ontario.org
Applications are internally reviewed for completeness, eligibility and use of funds prior to evaluation by expert
reviewers with business and domain expertise. Upon review of your Application, OCE may request additional
information or clarification to determine project eligibility. You will be notified via e-mail and asked to follow up
accordingly. This documentation will be appended to the submission. The Expert Reviewers will assess the
proposal and make a funding recommendation to OCE. Final funding decision is made by OCE.
For assistance with preparation of applications, contact an OCE Business Development Manager.
For MI Member Institutions, assistance with preparation of applications, contact MI at jterry@marsinnovation.com
For program inquiries including general inquiries about the program, eligibility, funding, timelines, and application
process contact the OCE Application Support Team at application-support@oce-ontario.org or (416) 861-1092 x2400
For further questions contact Sam Saad, Program Manager at sam.saad@oce-ontario.org or (416) 861-1092 x1097.
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ADMINISTRATIVE PURPOSES ONLY APPLICATION #:
SUBMISSION DATE:
Medical Sciences Proof of Principle (MSc PoP) Program
Proposal Questions
NOTE: THE INSTRUCTION PAGE IS TO BE REMOVED PRIOR TO UPLOADING THE PROPOSAL QUESTION PAGE TO THE
ON-LINE SYSTEM).
PART A: APPLICANT INFORMATION
PROJECT TITLE:
(NOTE: TWO APPLICANT SECTIONS HAVE BEEN PROVIDED BELOW. IF THERE ARE MORE THAN TWO
APPLICANTS TO THE PROPOSAL, PLEASE ADD ADDITIONAL SECTIONS AS REQUIRED).
LEAD APPLICANT
Organization Name:
Applicant Name (Dr., Mr., Ms.):
Position:
Applicant Name (Dr., Mr., Ms.):
Position:
Partner Representative (Dr., Mr.,
Ms.):
Position:
CO-APPLICANT 1
Organization Name:
PROJECT PARTNERS
Partner (Organization’s Name):
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ADMINISTRATIVE PURPOSES ONLY APPLICATION #:
SUBMISSION DATE:
Medical Sciences Proof of Principle (MSc PoP)
Proposal Questions
PART B: PROPOSAL
Refer to the bulleted questions in each section to guide the content of your proposal.
B1: APPLICANT INFORMATION
Describe which scenario best describes the opportunity presented
a) Licensing opportunity to an existing Ontario-based Company. Describe the likely receptor for this
innovation and their Ontario operations
b) Pre-company formation stage. Describe the plans to incorporate and transfer out of the academic
institution. Identify your plans to develop management, advisors, mentors and Board of Directors
c) Start-up spun out of academic institution. Provide details into the Company Profile section of the on-line
application. In addition, identify key company management, advisors, mentors and Board of Directors, or
your plans to develop these. (Note: Full details to be included will be outlined in Part D, D1: Project Plan,
Budget Justification and Team)
B2: TEAM/INSTITUTION COMMITMENT TO THE PROJECT
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Describe project team members and commercialization champion
o Role and decision making process (experiments, design, meetings, supervision, etc.)
o Expertise (academic affiliation, business or commercialization)
o Commitment to the project (time, resources and priorities)
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Medical Sciences Proof of Principle (MSc PoP)
Proposal Questions
B3: INTELLECTUAL PROPERTY POTENTIAL
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Briefly describe the technology and the history of its development to current status, include the stage of the
innovation (proof of principle, prototype, etc.) and competitive advantages
Describe the status of the technology from an intellectual property perspective (technology inventors, preexisting obligations, patent status, IP ownership)
Was a patent search or freedom to operate search performed? If yes, please list up to 10 of the most
relevant patents
Provide a short summary of what is needed to further develop the technology, including the competitive
advantage of the technology in the particular sector/industry.
B4: CHALLENGE AND MARKET OPPORTUNITY
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Briefly describe the market opportunity/challenge gap that your innovation will address and its magnitude
Summarize market and customer research that you (or others) have conducted to validate the opportunity
and total addressable market size
Who are the paying customers and end user? Describe their need(s) and limitations of current solutions.
What are the barriers that need to be overcome to bring the innovation to market?
Describe how the technology addresses defined or emerging needs in existing, developing and/or entirely new
markets
Describe your knowledge of the current industry environment in relation to the technology or product, and if
potential partners have been contacted. What marketing efforts have been carried out to date for this
opportunity
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Medical Sciences Proof of Principle (MSc PoP)
Proposal Questions
B5: POTENTIAL FOR COMMERCIAL DEVELOPMENT
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Provide a list of risk factors that may prevent or impede the adoption of commercialization
What is the proposed business model?
What is the likeliest route or scenario by which the technology can achieve commercial application?
Describe the economic benefit to Ontario (e.g. jobs, revenue, etc.)
Identify regulatory hurdles that must be addressed to bring the technology, product or service to market, if
applicable and how they will be addressed.
B6: PROJECT PLAN, BUDGET JUSTIFICATION AND TEAM
Referring to the Activity Table and Budget completed on-line, address the following:
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Detail each project plan activity and expected outcome
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Identify key decision points and potential technical hurdles in the plan
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Provide budget justification of how to the OCE and Partner Contributions will support the successful
completion of the project
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What is the amount and nature of the in-kind contributions (e.g. experimentation, design, travel, meetings,
supervision, etc.?)
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Briefly summarize the further development of the technology required to commercialize the technology.
Specify sources of additional funding required for the technology to be commercialized.
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