BIOMOLECULES Carbohydrate Protein Building Block Uses Examples Test Simple sugars Ready source of energy Glucose Glycogen Cellulose Starch • Enzymes (ase) Hemoglobin Antibodies Protein hormones (insulin) • Reacts with Biuret Solution Fats, oils • Leaves oily spot on brown paper bag DNA, RNA • DNA stains (methylene blue) Amino acids • Transport • • • Lipid Fatty Acids • • Nucleic Acid Nucleotide Speed up reactions Immunity Cell communication Back up energy source In membrane Store and transmit genetic info • STARCH turns purple in iodine SUGARS react with Benedict’s Solution CELLS • • • • E U K A RYOTIC P ROK A RYOTIC • Prokaryotic cells have DNA and ribosomes, but they have no internal membranes! (They don't have a nucleus) They have ribosomes to make proteins These are the simplest cells Examples are bacteria, like those that cause strep throat. • • • • • Eukaryotic cells have their DNA surrounded by a membrane. (They have a nucleus). Two examples shown are plant cells and animal cells, but fungi and protists are also eukaryotic Notice, plants have chloroplasts (for photosynthesis) and cell walls made of cellulose. Animal cells don't have these parts. Also, plant cells have a larger vacuole for storage. Both plants and animals have mitochondria to make ATP. All eukaryotic cells have ribosomes to make protein These cells are more complex than prokaryotic cells. CELL MEMBRANE • The plasma membrane surrounds EVERY cell. • It is made of lipid and protein • It controls what goes in and out of a cell. • Associated with HOMEOSTASIS CELL TRANSPORT Diffusion Osmosis Active Transport Movement from high to low concentration Movement of water from high to low WATER concentration across a membrane Movement from LOW concentration to HIGH concentration No energy required No energy required USES ATP PHOTOSYNTHESIS AND RESPIRATION CONVERTS SUNLIGHT TO CHEMICAL ENERGY CONVERTS ENERGY IN FO O D (G LU C O S E ) TO AT P Cellular Respiration • Takes place in mitochondrion • Releases the energy stored in glucose • AKA aerobic respiration (NEEDS oxygen) AEROBIC VS ANAEROBIC RESPIRATION A ERO B IC R ES PIR AT IO N A N A E RO B IC R E S PIR AT IO N • Does not use oxygen • Makes only 2 ATP • Requires oxygen • Makes A LOT of ATP • Produces carbon dioxide and water • Also called fermentation • Happens in mitochondrion • Happens in cytoplasm (cytosol) • Small amount of ATP • YEASTS make ethyl alcohol • BACTERIA and MUSCLE CELLS (w/o O2) make LACTIC ACID ATP CYCLE CLICK THE ICON FOR SOUND ASEXUAL VS SEXUAL REPRODUCTION ASEXUAL REPRODUCTION • Creates identical copies (clones) • Only involves MITOSIS • ONE parent involved • Common in bacteria and unicellular protists SEXUAL REPRODUCTION • Adds genetic variation • Involves meiosis and fertilization • TWO parents involved • Diploid and haploid cells MITOSIS AND MEIOSIS • • MITOSIS MEIOSIS One division 2n 2n • • • (same number of chromosomes) • Results in 2 genetically identical cells Two divisions 2n n • Half the number of chromosomes • • Results in 4 DIFFERENT haploid cells Forms gametes (egg and sperm) DNA • DNA is a polymer of nucleotides. • A nucleotide is made up of three parts: a sugar, a phosphate and one of four bases • In DNA, the bases are A, T, C, and G • DNA’s shape is a double helix • The two strands are held together by HYDROGEN bonds • A binds to T • C binds with G DNA REPLICATION • • • Process of DNA copying itself Steps • DNA Unzips (Hydrogen bonds break) • Each side acts as a template • New DNA nucleotides are added according to base-pairing rules • Two new molecules of DNA result – each with one old and one new strand. Happens in INTERPHASE (before mitosis or meiosis) PROTEIN SYNTHESIS • Remember, genes are made of DNA and are in the nucleus • Genes (DNA) contain the instruction for making a protein • In transcription, DNA is used to make mRNA in the nucleus • mRNA then leaves the nucleus and goes to the ribosome • In translation, tRNA then brings amino acids in the proper order to make the protein on the ribosome. DNA mRNA protein Made of amino acids PROTEIN SYNTHESIS DNA RNA PROTEIN •DNA is in nucleus •GENES (made of DNA) hold code for protein •mRNA is made in nucleus •TRANSCRIPTION •Remember base pairing rules •mRNA goes to ribosome •3 bases on mRNA is a codon – each codon codes for one amino acid •tRNA brings the right amino acid to the mRNA •Anticodon on tRNA base pairs with codon on mRNA CAN YOU IDENTIFY THE PARTS? 1. 2. 3. 4. 5. 6. 7. 8. 9. 10. DNA mRNA Nucleus Cytoplasm Ribosome Codon Anticodon tRNA Amino acid Protein (polypeptide) READING THE CODON CHART • Be sure to use mRNA • You won’t have to memorize this! • What amino acid is coded for by the DNA ATA GAG First convert DNA to mRNA ATA GAG UAU CUC UAU = tyr CUC = Leu GENETICS We have two genes for each trait – this is our GENOTYPE One gene came from mom, one from dad If the genes are alike, the individual is homozygous (RR, rr) If the genes are different , they are heterozygous (Rr) Some genes are dominant and others are recessive We only show a recessive trait if we have no dominant gene RR and Rr would “look” dominant rr would look recessive This diagram shows the cross between 2 heterozygous purple flowers Cross is: Bb x Bb Notice that 75% are purple and 25% white SEX LINKAGE Females are XX Males are XY Sex-linked traits are on X chromosome Trait is more common in MALES Examples are colorblindness and hemophilia (blood fails to clot) • Males give X chromosomes to their daughters and Y’s to their sons • Moms give X’s to both daughters and sons CODOMINANCE – BLOOD TYPE • Four blood types A, B, AB, O Three different alleles: A, B or neither A = AA or AO B = BB or BO AB = AB O = OO Agglutinogen = protein PEDIGREES Tracing traits through generations • Males are squares • Females are circles • Horizontal line means married • Vertical line means children • Filled in circle means the individual HAS the condition • Can you identify the genotypes of individuals 4, 7, 12? 4 = Ee (parent 2 had to give an e) 7 = Ee (child is ee, so they had to have one e) 12 = ee (affected with recessive condition) XY = male 3 21’s = Down Syndrome • • • • • In humans, 22 pair of autosomes 1 pair of sex chromosomes XX = female XY = male Extra chromosomes a result of non-disjunction • Chromosome pairs fail to separate in meiosis • One example is DOWN SYNDROME (extra 21) • Another example is KLINEFELTERS (XXY) GENETIC TECHNOLOGY DNA FINGERPRINTING TRANSGENIC ORGANISMS • Organisms that have 2 different kinds of DNA • Gene cloning • Uses bacteria to make human proteins like insulin • Use gel electrophoresis to compare DNA fragments • IF DNA matches, it’s from the same individual Evidence points to suspect 2 EVOLUTION – CHANGE OVER TIME EVIDENCE N AT U R A L S E LE C T IO N • Fossil evidence • Credited to Charles Darwin • Fossils found in sedimentary rock • Lower level fossils are older and more PRIMITIVE • We can compare fossils to modern organisms • Similar structure suggests common ancestor • Biochemical evidence • DNA and protein similarities suggest common ancestor • Organisms in populations have variations that can be passed from generation to generation • More organisms born that environment can support • Organisms compete for resources • Those organisms with favorable variations have more babies and the population evolves Which type of plant is most closely related to flowering plants? CONIFERS HISTORY OF CLASSIFICATION SYSTEMS o Aristotle – Plants and Animals o Linneaus – developed BINOMIAL NOMENCLATURE o TWO KINGDOMS: plants and animals o THREE kingdoms: plant, animal, Protist o FIVE kingdoms: plant, animal, Protist, fungi, Moneran CLASSIFICATION K •Kingdom P •Phylum C •Class O •Order F •Family G •Genus S •Species Scientific name is genus and species name. Organisms in same genus are closely related FIVE KINGDOM CLASSIFICATION Moneran Protist Fungi Plant Animal •Bacteria •Prokaryotic •No nucleus •Have cell wall •Unicellular •Can be heterotrophic or autotrophic •Protozoans, algae •Eukaryotic •Have nucleus • Some have cell wall •Mainly unicellular •Can be heterotrophic or autotrophic •Mushroom, yeast •Eukaryotic •Have nucleus •Have cell wall •Mainly multicellular •heterotrophic •Moss, fern, trees, flowers •Eukaryotic •Have nucleus •Have cell wall •All multicellular •autotrophic •Sponge, annelids, amphibians, birds, mammals •Eukaryotic •Have nucleus •No cell wall •All multicellular •heterotrophic DICHOTOMOUS KEY • • • • Always begin with #1 Follow directions using choices given What shape is “Gina”? Equilateral triangle TYPES OF PLANTS Bryophytes Gymnosperms Angiosperms •Non-vascular •No xylem or phloem •Examples are mosses •They are small •Have to be near water •No pollen, seeds, flowers, or fruits •Vascular •Xylem to move water •Phloem to move food •Examples are conifers •Have pollen (sperm) •Have seeds on cones •No fruits or flowers •Vascular •Xylem to move water •Phloem to move food •Examples are flowering plants like oak trees, corn, and roses •Have pollen (sperm) •Have seeds in fruits •Have flowers PLANT ADAPTATIONS ROOT, STEM, LEAF Roots are adapted to absorb water with root hairs Leaves are adapted for photosynthesis by being flat and green Stems move water with xylem FLOWERS AND FRUITS Flowers have bright petals to attract pollinators Pollen (Sperm) can be transferred by animals When egg joins with pollen, a seed is formed in the ovary The ovary becomes the fruit Fruit surrounds and protects seed Fruit also helps get baby plants in seeds away from parent plant TYPES OF ANIMALS Annelids Insects Amphibians Mammals •Segmented worms •No backbone •“breathe” through skin •Closed circulatory system •External fertilization •External development •No backbome •Three body segments •Six legs •Wings •Open circulatory system •External fertilization •Females may store sperm •External development •metamorphosis •Have backbone •Moist skin •Gills when young, lungs when adult •Three chambered heart •Cold-blooded •External fertilization •External development •Metamorphosils •Jelly like egg •Backbone •Hair •Milk glands •Lungs •Four chambered heart •Warm-blooded •Internal fertilization •Internal development •Amniote egg DISEASE CAUSING VIRUSES VIRUS STRUCTURE VIRAL REPRODUCTION A virus is not made of cells • Virus can’t reproduce unless it is inside a living cell • The virus uses the cells enzymes and ribosomes to make DNA and protein • New viruses either bud off of the cell or the cell bursts, releasing lots of viruses It is nucleic acid (DNA or RNA) surrounded by protein coat (Capsid) BACTERIA VS VIRUSES BACTERIA VIRUS • Made of cells • Not made of cells • MUCH SMALLER THAN CELLS • Can’t be killed by antibiotics • Example of diseases caused by viruses are AIDS (HIV), Smallpox, Influenza • Can be killed by antibiotics • Examples of disease caused by bacteria is strep throat INTERNAL AND EXTERNAL FACTORS IN DISEASE Malaria PKU Lung Cancer Diabetes Skin Cancer Light skinned people don’t have the natural melanin protection of darker skinned people Overexposure to sunlight can trigger the changes that lead to skin cancer Individuals who have the sickle cell trait (heterozygous) aren’t as affected as homozygous individuals Individuals who have PKU can’t break down phenylalanine If it builds up it can cause mental retardation Lung cancer is uncontrolled growth of cells in the lungs Diabetes results from when the pancreas fails to make enough insulin Mosquitoes transmit malaria Keep individuals with PKU on a diet, they don’t have brain damage Individuals who smoke are more likely to get lung cancer Individuals who are overweight and who don’t exercise seem to be more affected IMMUNITY B-cells T- helper cells T-killer cells •White blood cell •Make antibodies •White blood cell •Help coordinate immune response •White blood cell •Kill virus infected cell PASSIVE VS. ACTIVE IMMUNITY ACTIVE IMMUNITY PASSIVE IMMUNIT Y • Person does NOT make memory cells or antibodies • Antibodies only are transferred • Doesn’t provide longterm protection • Natural: from breastfeeding • Artificial: Rabies “shot” • Person DOES make antibodies AND memory cells • Provides long term immunity • Natural: you have disease • Artificial – you get a VACCINATION BEHAVIORAL ADAPTATIONS BEHAVIOR IS ANY THING AN ANIMAL DOES. ANIMAL BEHAVIORS ALSO HELP ANIMALS SURVIVE AND/OR REPRODUCE. o Innate behavior is also called inborn behavior. o It is programmed in DNA o Innate behaviors include reflexes and instincts o Examples o human suckling. o spiders spinning webs o Migration: birds flying south for the winter o Hibernation – dormant when cold o Estivation – dormant when hot LEARNED BEHAVIOR Imprinting • Learning who your Mother is • Lorenz geese Conditioning Habituation • Pairing stimuli • Pavlov’s Dogs • Learning to ignore • Dog no longer sees human as threat Trial and Error •Learning by trying SOCIAL BEHAVIOR Communication •Can be with words, signals or chemicals (pheromones) Courtship •Behavior to get a mate •Dances, songs Territorial •Fighting fish ECOLOGY AND ECOSYSTEMS Ecosystem Community Population •Includes abiotic and biotic factors •Biomes are examples •Includes all the LIVING things •All of one species in one area •Can reproduce with each other FOOD CHAINS Original source of energy for most chains is the sun 1st trophic level is producer 2nd trophic level is primary consumer 2rd trophic level is secondary consumer Decomposer not shown on chain, but they recycle nutrients Secondary Consumer (bird) Primary Consumer (snail) Producer (grass) Energy is “lost” as you mover “up” the food chain SYMBIOSIS Mutualism Parasitism Commensalism •n mutualism, BOTH organisms BENEFIT •this is a + / + relationship •The picture shows E. coli, a type of bacteria that live in your intestine. •The bacteria get a place to live; we get the vitamin K they make. This is good for both. •In parasitism, the PARASITE BENEFITS by getting food and shelter from the HOST •This is a + / - relationship •In the example shown, the TICK is the parasite and feeds off of the blood of the human HOST. This is good for the tick, but bad for the human. •In commensalism, one organism BENEFITS while the other is NOT AFFECTED •This is a +/ 0 relationship •The picture above shows orchids living in trees. This is good for the orchid, because it allows the orchid to get sunlight. It doesn't affect the tree, because the orchid doesn't help or hurt it. PREDATION • Predator EATS Prey • The populations cycle • Predator has lower curve • There can’t be more predators than prey POPULATION GROWTH EXPONENTIAL GROWTH LOGISTIC GROWTH J-curve S-curve Occurs when unlimited resources are available Occurs because resources are limited Carrying capacity reached HUMAN POPULATION GROWTH Overpopulation of humans leads to • Destruction of habitats (pollution and/or destroying) • Loss of biodiversity • Introduced species • Outcompete native species CARBON CYCLE • • Cycling of carbon and oxygen Three main processes • Photosynthesis – plants use carbon dioxide; produce oxygen • Respiration – uses oxygen, produces carbon dioxide (both plants and animals) • Combustion – burning – releases more carbon dioxide Greenhouse Effect • Carbon dioxide traps heat in the atmosphere, making life possible • Increased carbon dioxide can make temperatures rise more • Human activities can lead to GLOBAL WARMING BE A GOOD STEWARD