COURSE SYLLABUS, SPRING 2015 Tulsa Community College, SEC Campus CHEM 2353 – Intro to Biochemistry INSTRUCTOR: William T. Briscoe, Ph.D. CHEM 2353-302-22165 M Lecture: Science and Mathematics Division Asso. Dean: Lyn Kent Office: SE 8125 Phone No.: 595-7742 OFFICE HOURS Mon: 1:00- 3:30 Tue: 1:30- 3:00 Wed: 1:00- 3:30 Instructor: Office: Phone No.: e-mail: 4:00-6:50 SE 8260 William T. Briscoe, Ph.D. SE 8265 595-7680 bill.briscoe@tulsacc.edu Thu: 1:30- 3:00 Fri. 9:30-12:00 or by appointment COURSE PREREQUISITE: This course has a pre-requisite of Organic Chemistry I (CHEM 2145; which requires CHEM 1315 & 1415 as its prerequesites), and some knowledge of organic chemistry. It is highly recommended that this course be taken after Organic Chemistry II (CHEM 2445) but can be taken without it. If there are any questions, the student should discuss their background in organic chemistry with the instructor. COURSE DESCRIPTION Intro to Biochemistry is a survey of a topic which is present in the curriculum of most courses of study that lead to a professional career in a health related area. Traditional Biochemistry is often found to be a difficult course due to the new vocabulary and fundamental concepts unique to it. Thus, this course is designed to provide the student with a preview of the highlights of the course material so that he will already be familiar with the vocabulary and fundamental concepts when the traditional course is encountered. At present, this course will transfer to some schools as a science elective, but may not transfer at all to some schools. Check with your next institution for details. Lecture: 3 hours TEXTBOOK AND OTHER MATERIALS Concepts in Biochemistry, 3nd edition, 2005, Rodney F. Boyer, John Wiley & Sons, Publishers. Metabolic Pathways, 22nd ed., Chart, 12X19 in., 2003, Donald E. Nicholson, Sigma-Aldrich, St. Louis, MO. Catalog No. M3782 Stapler with which to staple homework papers together Optional Materials: Molecular Model Set for Organic Chemistry, Molymod, Prentice Hall GENERAL EDUCATION GOAL STATEMENT General Education courses at TCC ensure that our graduates gain skills, knowledge, and abilities that comprise a common foundation for their higher education and a backdrop for their work and personal lives. TCC’s General Education goals are: Critical Thinking, Effective Communication, Engaged Learning, and Technological Proficiency. COURSE OBJECTIVES Biochemistry contains both theoretical and practical knowledge. This class will provide an overview of biochemistry and an introduction to its unique vocabulary. Included in this course will be an overview of: molecular structures and bonding in biochemicals, the structures and nomenclature of carbohydrates, lipids, proteins, and nucleic acids, enzymology, DNA replication, transcription, and translation, basic catabolism and anabolism including the Krebs cycle and electron transport system. PROFESSIONALISM AND ATTENDANCE: It is assumed that students enrolling in a course at this level are headed toward a professional career. Because prospective future employers, clients, patients, and admissions committees will make decisions of your future association with them based on, among other things, your reputation of projecting a professional image, it is important to be projecting that image now. A professional image includes such character traits as attendance, punctuality, thoroughness, attentiveness, attitude toward authority, honesty, and appearance (dress and grooming). Absences will usually be reflected in the student’s ability to complete the course work in a satisfying manner, as well as be counted in the “Professionalism” grade. COURSE WITHDRAWAL: The deadline to withdraw from a course shall not exceed 3/4 the duration of any class. Check the TCC Academic Calendar for the deadline that applies to the course(s). Begin the process with a discussion with the faculty member assigned to the course. Contact the Advisement Office at any TCC campus to initiate withdrawal from a course ('W' grade) or to change from Credit to Audit. Withdrawal and/or change to an audit from a course after the drop/add period can alter the financial aid award for the current and future semesters. Students may receive an outstanding bill from TCC if the recalculation leaves a balance due to TCC. Students who stop participating in the course and fail to withdraw may receive a course grade of “F,” which may have financial aid consequences for the student. COMMUNICATIONS: Email communications: All TCC students receive a designated “MyTCC” email address (ex: jane.doe@mail.tulsacc.edu). All communications to you about TCC and course assignments will be sent to your MyTCC email address; and you must use MyTCC email to send email to, and receive email from, the instructor regarding this course. Inclement Weather: TCC rarely closes. If extreme weather conditions or emergency situations arise, TCC always gives cancellation notices to radio and television stations. This information is also posted on the TCC website (www.tulsacc.edu). Notification is also available via phone and text messaging for those who have registered with TCC Alerts. GENERAL EDUCATION GOALS: General Education courses at TCC ensure that our graduates gain skills, knowledge, and abilities that comprise a common foundation for their higher education and a backdrop for their work and personal lives. TCC’s General Education goals are: Critical Thinking, Effective Communication, Engaged Learning, and Technological Proficiency. CLASSROOM ETIQUETTE: Open and mutually respectful communication of varied opinions, beliefs, and perspectives during classroom or online discussion encourages the free exchange of ideas that is essential to higher learning and to the ability to learn from each other. Use of any electronic device is at the discretion of the instructor. SYLLABUS CHANGES: Occasionally, changes to the syllabus may be necessary. Students will be notified of any changes to the syllabus in class. Disability Resources: It is the policy and practice of Tulsa Community College to create inclusive learning environments. Accommodations for qualifying students in compliance with the Americans with Disabilities Act (ADA) and Section 504 of the Rehabilitation Act are available. To request accommodations, contact the Education Access Center (EAC) at eac@tulsacc.edu or call (918) 595-7115 (Voice). Deaf and hard of hearing students may text (918) 809-1864. ACADEMIC DISHONESTY: Academic dishonesty (cheating) is defined as the deception of others about one’s own work or about the work of another. Academic dishonesty or misconduct is not condoned or tolerated at campuses within the Tulsa Community College system. Tulsa Community College adopts a policy delegating certain forms of authority for disciplinary action to the faculty. Such disciplinary actions delegated to the faculty include, but are not limited to, the dismissal of disrespectful or disorderly students from classes. In the case of academic dishonesty a faculty member may: require the student to redo an assignment or test, or require the student to complete a substitute assignment or test; Record a "zero" for the assignment or test in question; Recommend to the student that the student withdraw from the class, or administratively withdraw the student from the class; Record a grade of "F" for the student at the end of the semester. Faculty may request that disciplinary action be taken against a student at the administrative level by submitting such request to the Dean of Student Services. PLAGIARISM POLICY Plagiarism is claiming, indicating, or implying that the ideas, sentences, or words of another writer are your own; it includes having another writer do work claimed to be your own, copying the work of another and presenting it as your own, or following the work of another as a guide to ideas and expression that are then presented as your own. This includes copying another’s homework. The student should review the relevant sections of the TCC Student Code of Conduct Policy Handbook. INSTITUTIONAL STATEMENT: Each student is responsible for being aware of the information contained in the TCC Catalog, TCC Student Handbook, Student Code of Conduct Policy Handbook, and semester information listed in the class schedule. All information may be viewed on the TCC website: www.tulsacc.edu LEARNING SUPPORT SERVICES AND COMPUTER ASSISTED INSTRUCTION A complete set of computer programs for the General Chemistry courses is available for use in the Math Lab, SE 8150. A variety of CD-Rom tutorials are available for purchase in the bookstore to aid in studying. The tutorials are extremely helpful in preparing for class and exams. Access to computing resources is a privilege granted to all TCC faculty, staff, and students. Use of TCC computing resources is limited to purposes related to the College’s mission of education, research, and community service. Student use of technology is governed by the Computer Services Acceptable Use Statements/Standards found in the TCC Student Code of Conduct Policy Handbook. These handbooks may be obtained by contacting any Student Activities or Dean of Student Services office. TEACHING METHODS All lecture material must be read prior to class presentation period. Problems from the textbook should be worked. Specific problems may be assigned to be handed in for grading. EVALUATION TECHNIQUES A. Exams— Four (4) 100 points each. The examinations will cover the lecture material and all the material in the assigned chapters in the textbook. The exact formats will be explained in class. 1. No make-up tests will be given, unless in case of extreme emergency and at the discretion of the instructor (my phone number and e-mail address in at the first of this syllabus). If you miss a scheduled exam for a legitimate reason, the grade for that exam will be replaced with the percentage value of your score on the cumulative final exam. If you miss a subsequent exam, the grade will be recorded as zero. 2. The final exam is mandatory, worth 150 points and CANNOT be made up. C. Homework 1. Homework problems from the text will be assigned throughout the course. These problems will aid the student in obtaining a thorough understanding of the material. Late homework will be accepted up to one week after the scheduled turn-in date at a 20% reduction in grade. Late homework due to excused absence on the date due may be turned in on the next class day attended without penalty. GRADING SYSTEM Exam Grades (4 @ 100 pts. ea.) Homework Professionalism (50 pts.) Final exam (150 pts.—mandatory) GRADING SCALE 90 -100% 80 - 89% 70 - 79% 60 - 69% Below 60% = = = = = A B C D F 400 points 100 points 50 points 150 points 700 points TENTATIVE LECTURE SCHEDULE CHE 2353 SPRING, 2015 DATE Jan. 12 Jan. 19 Jan. 26 Feb. 2 Feb. 9 READING ASSIGNMENTS Ch. 1-2 Intro., information flow, water and biochemistry NO CLASS—Martin Luther King, Jr. Day Ch. 3-4 Amino acids, protein structure and function Ch. 5 Enzymology Ch. 6-7 Enzymology/Carbohydrates Feb. 16 EXAM 1: Chapters 1-6 Feb. 16 Feb. 23 Mar. 2 Ch. 7-8 Ch. 8-9 Ch. 10 Mar. 9 EXAM 2: Chapters 7-10 Mar. 9 Mar.16-21 Mar. 23 Mar. 30 Ch. 11 Apr. EXAM 3: Chapters 11-12 6 Ch. 11-12 Ch. 12 DNA Replication & Transcription SPRING BREAK DNA Transcription/Translation Translation and Protein Synthesis/Regulation of Gene Expression Apr. 6 Apr. 13 Apr. 20 Apr. 27 Ch. Ch. Ch. Ch. May May EXAM 4: Chapters 14-18 (turn in take-home exam) FINAL EXAM: [scantron] (comprehensive) 4:00-5:50 4 4 14-15 15-16 16-17 18 Carbohydrates/Lipids Lipids/Membrane Transport Nucleic Acid structure and function Metabolism of Carbohydrates Krebs Cycle/NADPH production NADPH production/Electron Transport Metabolism of Fatty Acids and Lipids Homework Assignments: Underlined problems are to be turned in for grading. Homework Chapter 1: Homework Chapter 2: Homework Chapter 3: Homework Chapter 4: Homework Chapter 5: Homework Chapter 6: Homework Chapter 7: Homework Chapter 8: Homework Chapter 9: Homework Chapter 10: Homework Chapter 11: Homework Chapter 12: Homework Chapter 14: Homework Chapter 15: Homework Chapter 16: Homework Chapter 17: Homework Chapter 18: 4, 10, 11, 13, 14, 19, 22, 23 2abc, 5abef, 7, 9, 10abc, 12acd, 13ac, 14bd, 15d, 17, 19abeg, 21, 24, 33. 4, 5, 6, 7, 11, 14, 15, 19, 25ab, 27. 9, 15, 20, 24, 27abdhi, 29 3, 4, 7, 8, 11, 18, 21 ,27 4, 6, 12, 13, 19, 21, 22, 24 3bdegij, 5, 8, 11abd, 13, 14, 22, 27 4b, 6b, 7, 14, 17, 19, 20ab. 7, 9abcd, 10, 17 2ab, 5, 6, 12, 14ab, 16, 22, 24, 26, 28, 31, 32 2, 3, 4, 5, 7, 17, 19, 23a 6, 7, 8, 11, 12, 14, 16, 17, 23, 24, 27, 31 2, 3, 5, 8, 18, 19, 21, 24, 27 6, 10, 11, 14, 15, 20ad, 25ab, 26, 28 3, 5, 6, 9, 11, 15, 16, 19, 20abd, 22 2, 3, 5, 15, 20, 21 8, 12, 13, 19, 20, 23