Licensing Opportunity
from the University of Rhode Island
Biofunctionalized Polyester Material for Surface
Treatment and Biomodification
Description of Invention: The invention features a method of treating polyester material to generate
functional carboxylic acid and amine groups. These functional groups can be used as sites for covalent bond
formation to attach chemical or biological moieties. This bifunctionalized polyester polymer can be used in any
medical application in which biocompatible polymers are used.
Potential Areas of Application:
1) In a desired embodiment, the chemical compound consists of a commercial finish selected from the
group consisting of flame retardants, repellents, antistatic agents, and dyes.
Main Advantages of Invention:
1) This invention features a method of generating a functionalized polyester material. This method
includes incubating the polyester material with ethylene diamine in solution (aqueous or organic)
under conditions that result in functionalization of the polyester material.
2) The functionalization of the material consists of creation of carboxylic acid and amine groups within
the polyester backbone. The carboxylic acid and amine groups can then be used as sites to attach
other chemical compounds and biologically-active agents to the polyester backbone via an ionic or
covalent bond.
Lead Inventor:
Martin Bide et al, TMD
Status:
US patent application 10/352,286 filed on January 27, 2003 issued as US patent 7,037,527 on May 2, 2006
Bifunctionalized Polyester USPTO Website Link
Publications (with links):
Category: Biological, Pharmaceutical, Life Sciences
Licensing Status:
Available for licensing
Reference #:01-0919
Please contact David R. Sadowski or Raymond Walsh - Division of Research & Economic Development, University of
Rhode Island, 75 Lower College Rd. Suite 001, Kingston, RI 02881; 401-874-4807 or Fax 401-874-7832
http://www.uri.edu/research/tro/executive/sadowski.html
Rev. 01-14-10