Maryland State Department of Education Academy of Health Professions Course 1: Foundations of Medicine and Health Science Unit 2: Medical Assessment Section 4: Nervous System ANSWER KEY AND RUBRICS UNIT 2: INTRODUCTION Many different fields of biology, chemistry, and physics converge in the application of medical diagnostics, where a combination of chemical tests, physical evaluations, and advanced imaging techniques are used to assess body functions, and detect possible abnormalities. Many of these techniques are used in routine preventative care, but are also an essential part of the tools used to identify injuries in emergency room situations. In this unit, you will investigate different methods of evaluating body function, as well as learning basic anatomy, and the structure and function of selected body systems. Contents 2.4 Nervous System 2.4.1 Cranial Nerve Function 2.4.2 Neurological Assessment 2.4.3 Sheep Brain Dissection © Copyright, Stevenson University, 2009; AHP Course 1_Unit 2: Section 4_Teacher Version 2 Page 1 Name:_____________________________ 2.4.1. WORKSHEET 15: CRANIAL NERVES – ANSWER KEY Table 1. The Names and Function of the Twelve Cranial Nerves Cranial Nerve Cranial Nerve Name Function Number I Olfactory Nerve Smell II Optic Nerve Vision III Oculomotor Nerve IV Trochlear Inferior and lateral movement of the eyeball. V Trigeminal Nerve Main sensory nerve of the face. Responds to touch, pain, temperature. VI Abducens Nerve Lateral movement of the eye. VII Facial Nerve VIII Vestibulocochlear Nerve IX Glossopharyngeal X Vagus Nerve XI Accessory Nerve XII Hypoglossal Nerve © Eye movements, opening of eyelid, constriction of pupil, focusing. Major motor nerve of facial expressions, autonomic control of tear glands, nasal glands, salivary glands, and sense of taste. Hearing and equilibrium. Swallowing, gag reflex, salivation, regulation of blood pressure and respiration, sensations of touch, pressure, taste, and pain from the tongue, sensations of pain, touch and temperature from the external ear. Speech, swallowing, regulation of pulmonary, cardiovascular and gastrointestinal function. Sensations of hunger, fullness, and intestinal discomfort. Swallowing, movements of the head, neck, and shoulders. Tongue movements during speech, food manipulation, and swallowing. Copyright, Stevenson University, 2009; AHP Course 1_Unit 2: Section 4_Teacher Version 2 Page 2 2.4.2 Glasgow Coma Scale - Student Role Play Cards Patient 1 Patient 2 You will open your eyes and look at You will have your eyes open and the person examining you. look at the person examining you. You will speak normally and You will speak normally, but you answer questions appropriately are confused. You don’t know where you are, and give the wrong You will be able to squeeze the month and year when asked. examiner’s hands and stick your tongue out. You will be slow to follow the verbal commands, but will be able to do what is asked. Patient 3 Patient 4 Your eyes will be closed even if You will keep your eyes closed, someone pinches you. even if someone pinches you. You will make no sound, even if You will groan in response to being someone pinches you. pinched, but will not say any recognizable words. You will not respond to verbal commands at all, even if pinched. You will not follow commands, but if someone pinches you, you will try to push his or her hand away. Patient 5 Patient 6 Your eyes will be closed, even if Your eyes will be open and you will someone calls you loudly. You will be looking around you with an open them if pinched. anxious expression on your face. You will say “Don’t!” or “Stop!” You will not answer questions at when pinched, but do not speak all. If pinched you will groan, but whole sentences and do not answer do not say any recognizable words. any questions. You will not follow commands, but if someone touches you (including You will not squeeze the examiner’s hands or stick out your to pinch you) you will grab hold of tongue, but you will quickly push his or her hand with both of yours. his or her hand away if pinched. Don’t let go easily. Patient 7 Patient 8 Your eyes will be closed, even if Your eyes will be closed, but you someone pinches you. will open them briefly if anyone calls loudly. You will make no sound, even if someone pinches you. You will not answer questions. If anyone pinches you, you will groan You will not follow commands. or yell, but not say any recognizable You will lie in a position where words. your closed fists are lying beside You will not follow commands, but one another at the top of your chest if someone pinches you, you will (decorticate posturing) and will not quickly push his or her hand away. move from this position. © Copyright, Stevenson University, 2009; AHP Course 1_Unit 2: Section 4_Teacher Version 2 Page 3 Patient 9 Your eyes will be closed, but you will open them if someone speaks to you. You will speak normally, but you are confused. You don’t remember exactly what happened to you, and you give the wrong month if asked. You will be slow to follow commands like, “show me two fingers,” but you will be able to do so. Patient 11 Your eyes will be closed, even if someone talks to you or pinches you. You will answer questions correctly. Mention that your head hurts. If anyone asks you to open your eyes, refuse and say "the light makes my head hurt really bad." Follow commands appropriately, but don't open your eyes Patient 13 Your eyes will be open. Your speech won’t make much sense. In answer to a question like, “what month is this?” you will say something like, “he, umm, he . . . My jacket. I don't . . . You will not follow commands, but if someone pinches you quickly push his or her hand away. © Patient 10 Your eyes will be closed, even if someone pinches you. The only sound you make will be a weak groan when someone pinches you. You will not follow commands, but if someone pinches you, you will try to pull away or turn away from the pain. Patient 12 Your eyes will be closed, but you will open them if anyone pinches you. Your speech will be fairly clear when you are aroused by a painful stimulus, such as a pinch, but you will only say, “leave me alone" or "what are you doing?" and soon go back to sleep. If someone asks you a question while you are still awake, you'll say, “I don’t know,” and go back to sleep. You will not follow commands, but if someone pinches you, you will quickly push his or her hand away. Patient 14 Your eyes will be closed, even if someone pinches you. You will not make any sound, even if someone pinches you. You will not follow commands. If someone pinches you, put your arms rigidly at your side (decerebrate posturing). Copyright, Stevenson University, 2009; AHP Course 1_Unit 2: Section 4_Teacher Version 2 Page 4 Patient 15 Patient 16 Your eyes will be closed, even if Your eyes will be closed at first, but someone pinches you. you will open them if someone calls you loudly.(3) You will keep repeating some meaningless phrase like, "I want my You will not say any recognizable bunny slippers, I want my bunny words. If someone asks you a slippers, I want . . ." Keep it up question, look confused and say, continually, and if someone pinches "mmm ? " without opening your you, just say it louder. mouth.(2) You will sit up and rock You will not follow commands. If continually. You will not follow someone pinches you, pull away.(4) commands. If someone pinches you, push or slap the hand away. © Copyright, Stevenson University, 2009; AHP Course 1_Unit 2: Section 4_Teacher Version 2 Page 5 2.4.2 Glasgow Coma Scale - Student Role Play Cards – Teacher Version Teaching Note: The total Glasgow Coma Scale (GCS) score is given, and the scores for each individual assessment are given in parentheses. Patient 1 Patient 2 You will open your eyes and look at You will have your eyes open and the person examining you. (4) look at the person examining you. (4) You will speak normally and answer questions appropriately. (5) You will speak normally, but you are confused. You don’t know You will be able to squeeze the where you are, and give the wrong examiner’s hands and stick your month and year when asked. (4) tongue out. (6) You will be slow to follow the verbal commands, but will be able to do what is asked. (6) GCS SCORE: 15 Patient is fully oriented. GCS SCORE: 14 Patient loses 1 point for disorientation. Patient 3 Patient 4 Your eyes will be closed even if You will keep your eyes closed, someone pinches you. (1) even if someone pinches you. (1) You will make no sound, even if You will groan in response to being someone pinches you. (1) pinched, but will not say any recognizable words. (2) You will not respond to verbal commands at all, even if pinched. You will not follow commands, but (1) if someone pinches you, you will try to push his or her hand away. (5) GCS SCORE: 3 Completely unresponsive patients still score a 3 on this scale. © GCS SCORE: 8 Score of 5 given for motor response as patient is able to localize source of pain. Copyright, Stevenson University, 2009; AHP Course 1_Unit 2: Section 4_Teacher Version 2 Page 6 Patient 5 Your eyes will be closed, even if someone calls you loudly. You will open them if pinched. (2) You will say “Don’t!” or “Stop!” when pinched, but do not speak whole sentences and do not answer any questions. (3) You will not squeeze the examiner’s hands or stick out your tongue, but you will quickly push his or her hand away if pinched. (5) GCS SCORE: 10 Score of 5 given for motor response as patient is able to localize source of pain. Although “Don’t!” or “Stop!” are appropriate responses to pain, the patient is still not able to form a whole sentence and so scores a 3 for verbal response. Patient 7 Your eyes will be closed, even if someone pinches you. (1) You will make no sound, even if someone pinches you. (1) You will not follow commands. Patient 7 Your eyes will be closed, even if someone pinches you. You will make no sound, even if someone pinches you. You will not follow commands. You will lie in a position where your closed fists are lying beside one another at the top of your chest (decorticate posturing) and will not move from this position.. (3) Patient 6 Your eyes will be open and you will be looking around you with an anxious expression on your face. (4) You will not answer questions at all. If pinched you will groan, but do not say any recognizable words. (2) You will not follow commands, but if someone touches you (including pinching you) you will grab hold of his or her hand with both of yours. Don’t let go easily. (5) GCS SCORE: 11 Score of 5 given for motor response as patient is demonstrating ability to localize source of pain by grabbing the teacher’s hands. Patient 8 Your eyes will be closed, but you will open them briefly if anyone calls loudly.(3) You will not answer questions. If anyone pinches you, you will groan or yell, but not say any recognizable words. (2) You will not follow commands, but if someone pinches you, you will quickly push his or her hand away. (5) GCS SCORE: 10 GCS SCORE: 5 © Copyright, Stevenson University, 2009; AHP Course 1_Unit 2: Section 4_Teacher Version 2 Page 7 Patient 9 Your eyes will be closed, but you will open them if someone speaks to you. (3) You will speak normally, but you are confused. You don’t remember exactly what happened to you, and you give the wrong month if asked. (4) You will be slow to follow commands like, “show me two fingers,” but you will be able to do so. (6) GCS SCORE: 13 Patient 11 Your eyes will be closed, even if someone talks to you or pinches you. (1) You will answer questions correctly. Mention that your head hurts. If anyone asks you to open your eyes, refuse and say "the light makes my head hurt really bad." (5) Follow commands appropriately, but don't open your eyes. (6) GCS SCORE: 12 This patient is oriented, but cannot open his eyes due to pain, not because he is unconscious. Patient 10 Your eyes will be closed, even if someone pinches you. (1) The only sound you make will be a weak groan when someone pinches you. (2) You will not follow commands, but if someone pinches you, you will try to pull away or turn away from the pain. (4) GCS SCORE: 7 Patient 12 Your eyes will be closed, but you will open them if anyone pinches you. (2) Your speech will be fairly clear when you are aroused by a painful stimulus, such as a pinch, but you will only say, “leave me alone" or "what are you doing?" and soon go back to sleep. (4) If someone asks you a question while you are still awake, you'll say, “I don’t know,” and go back to sleep. (4) You will not follow commands, but if someone pinches you, you will quickly push his or her hand away. (5) GCS SCORE: 15 © Copyright, Stevenson University, 2009; AHP Course 1_Unit 2: Section 4_Teacher Version 2 Page 8 Patient 13 Your eyes will be open. (4) Your speech won’t make much sense. In answer to a question like, “what month is this?” you will say something like, “he, umm, he . . . My jacket. I don't . . .(3) You will not follow commands, but if someone pinches you quickly push his or her hand away. (5) Patient 14 Your eyes will be closed, even if someone pinches you. (1) You will not make any sound, even if someone pinches you. (1) You will not follow commands. If someone pinches you, put your arms rigidly at your side.(2) GCS SCORE: 4 This patient only scores 2 for motor response as she is exhibiting decerebrate GCS SCORE: 12 posturing. Patient 15 Patient 16 Your eyes will be closed, even if Your eyes will be closed at first, but someone pinches you. (1) you will open them if someone calls you loudly.(3) You will keep repeating some meaningless phrase like, "I want my You will not say any recognizable bunny slippers, I want my bunny words. If someone asks you a slippers, I want . . ." Keep it up question, look confused and say, continually, and if someone pinches "mmm ? " without opening your you, just say it louder. (3) mouth.(2) You will sit up and rock You will not follow commands. If continually. You will not follow someone pinches you, pull away.(4) commands. If someone pinches you, push or slap the hand away. (5) GCS SCORE: 9 Although the patient is speaking in complete sentences, the responses are not appropriate. © GCS SCORE: 9 Copyright, Stevenson University, 2009; AHP Course 1_Unit 2: Section 4_Teacher Version 2 Page 9 Student’s Name: _______________________ 2.4.3 WORKSHEET 16: SHEEP BRAIN DISSECTION – ANSWER KEY (www.brainu.org) I. Characteristics of a brain Write down 5 physical characteristics of your sheep brain? (e.g. how the brain feels, color of the brain, etc) ”Jello-like” . “Slick” . III. “Slippery” . IV. “Spongy” . “Convoluted” . I. II. V. II. Identifying brain regions Body directions to use when talking about the brain. Lateral = towards the side Medial = towards the middle © Copyright, Stevenson University, 2009; AHP Course 1_Unit 2: Section 4_Teacher Version 2 Page 10 a. Draw the LATERAL (outer side) view of your sheep brain (include the cerebellum and brainstem). Label the different lobes. You can peel the covering halfway back. b. Looking at your drawing, find the different lobes of the brain on your sheep brain. List the functions of each lobe. 1. Frontal Lobe The executive functions of the frontal lobes involve the ability to recognize future consequences resulting from current actions, to choose between good and bad actions (or better and best), override and suppress unacceptable social responses, and determine similarities and differences between things or events. Therefore, it is involved in higher mental functions. The frontal lobes also play an important part in retaining longer term memories which are not task-based. These are often memories associated with emotions derived from input from the brain's limbic system. The frontal lobe modifies those emotions to generally fit socially acceptable norms. 2. Parietal Lobe The parietal lobe plays important roles in integrating sensory information from various parts of the body, knowledge of numbers and their relations, and in the manipulation of objects. Portions of the parietal lobe are involved with visuospatial processing. © Copyright, Stevenson University, 2009; AHP Course 1_Unit 2: Section 4_Teacher Version 2 Page 11 3. Temporal Lobe The temporal lobe is involved in auditory processing and is home to the primary auditory cortex. It is also heavily involved in semantics both in speech and vision. 4. Occipital Lobe The occipital lobe is the visual processing center of the mammalian brain containing most of the anatomical region of the visual cortex It is also involved with visuospatial processing, color discrimination and motion perception. © Copyright, Stevenson University, 2009; AHP Course 1_Unit 2: Section 4_Teacher Version 2 Page 12 c. Draw the MEDIAL (inner side) view of the sheep brain. Label all of the brain parts that you can see. d. Look at your sheep brain and find out whether you have the right or left half (hemisphere). I have the _______________________ half (hemisphere). Find another group with the opposite half as yours and put both halves together. Compare the size of the brain to the size of a known object e.g. the whole sheep brain is as small as an apple. Write your comparison below. _____________________________________________________________________ _____________________________________________________________________ _____________________________________________________________________ _____________________________________________________________________ III. Coverings of the brain The dura mater (tough mother) is a protective covering of the brain. Does your sheep brain have a dura mater? (Hint: it looks white or purplish) The sheep brains may or may not have a dura mater. a. To take the dura mater off, locate the ROSTRAL end of your sheep brain. b. Using your thumb and index finger, peel the dura mater back towards the CAUDAL side. You might have to use the scissors to snip part of the dura mater at the ROSTRAL end. c. Remove the dura mater. © Copyright, Stevenson University, 2009; AHP Course 1_Unit 2: Section 4_Teacher Version 2 Page 13 d. Try pulling the dura mater apart. What do you notice? Does it rip like a piece of paper? Describe the properties of the dura mater. The students may describe the dura mater as tough, cannot pull apart, must cut. IV. First dissection – Exploring the Neuron and its parts a. Find the structure of a neuron from your textbook. Draw a neuron and label its parts. Diagram of neuron National Institute on Drug Abuse (NIDA) © Copyright, Stevenson University, 2009; AHP Course 1_Unit 2: Section 4_Teacher Version 2 Page 14 b. Place your brain with the cut-side (MEDIAL) down. c. Using your plastic knife, cut the brain about 1 inch from the rostral end (where the dent is located). d. Draw the inside of the cutoff piece. White matter Grey matter The dark area (grey matter) contains the cell bodies of neurons The light area (white matter) is made up of myelinated axons Image of cut section of sheep brain http://www.exploratorium.edu/memory/braindissection e. What do you notice about the cut surface? There seems to be two different layers of tissue: A white inner layer (white matter) and a darker outer layer (grey matter). f. Using the probe stick, poke the dark area? How does it feel? g. Using the probe stick, poke the light area? How does it feel? h. Identify the dark and light areas. © Copyright, Stevenson University, 2009; AHP Course 1_Unit 2: Section 4_Teacher Version 2 Page 15 V. Second dissection: Memory function of the brain What is the part of the brain that stores short term memories? The part of the brain that stores short-term memories is the prefrontal cortex. a. To find this brain part, slide your thumb along the outside (lateral side) of the brain stem until it disappears under the cerebrum. b. Keep wiggling your thumb and dig it gently under the cortex until you can’t push it in any more. c. Pull back the cerebrum so that you break the brain into two pieces. The memory center is the white C-shaped band of fibers and the grey matter inside them right around the area where the brain broke apart. d. Try to pull it out. i. What do you notice about it? ii. What kinds of things does a sheep need to remember? © Copyright, Stevenson University, 2009; AHP Course 1_Unit 2: Section 4_Teacher Version 2 Page 16 VI. Comparing Sheep Brains to Human Brains a. Label the brain parts in both the human and sheep brain picture. MEDIAL view of the human brain Cerebrum (frontal lobe) Corpus callosum CAUDAL Cerebellum MEDIAL view of the sheep brain Cerebellum (occipital lobe) Cerebellum CAUDAL Corpus callosum The outer layer of the brain is called the cerebral cortex is the thin layers of worm-like gray matter forming the surface of the hemisphere. The cortex is arranged in folds called gyri (singular = gyrus) which are separated from one another by folds called sulci (singular = sulcus). b. Observe the cortex in the sheep and the human brain. What do you notice about their relative size? This region is more extensive in the human brain. © Copyright, Stevenson University, 2009; AHP Course 1_Unit 2: Section 4_Teacher Version 2 Page 17 c. What is the role of this region of the brain? This region is responsible for all levels of cognition, which includes all thought and memory. d. Why does it differ between human and sheep? Humans have much higher levels of cognition. © Copyright, Stevenson University, 2009; AHP Course 1_Unit 2: Section 4_Teacher Version 2 Page 18