Name____________________________________________
HCT II
Human blood types are determined by genes that follow the CODOMINANCE pattern of inheritance. There
are two dominant alleles (I A and IB) and one receives allele (i).
1. Fill in the chart below
Blood Type
(phenotype)
Genotype
Can donate blood to:
Can receive blood from
O
AB
A
B
2. Write the genotype for each person based on the description:
a. Homozygous for the B allele
b. Heterozygous for the A allele
c. Type O
d. Type A and Type O parent
e. Type AB
f. Blood can be donated to everyone
g. Can only get blood from a Type O donor
3. Pretend that Brad Pitt is homozygous for the type B allele and Angelia Jolie is type O. What are all the
possible blood types of their baby?
4. Show the possible blood types for the children of a type O mother and a type AB father.
Name____________________________________________
HCT II
5. Mrs. Clink is type A and Mr. Clink is type O. They have three children named Matthew, Mark and Luke.
Mark is type O, Matthey is type A and luke is type AB. Bases on this information:
a. Mr. Clink must have the genotype_______________
b. Mrs. Clink must have the genotype _______ because _______has blood type __________
c. Luke cannot be the child of these parents because neither parent has the allele __________
6. Two parents thin their baby was switched at the hospital. It’s 1968 so DNA fingerprinting technology does
not exist yet. The mother has blood type O, the father has blood type AB and the baby has blood type B.
a. Mothers genotype:_________________
b. Father’s genotype:_________________
c. Baby’s genotype___________or_______________
d. Show your punnett square showing all possible genotypes for this children.
e. Was the baby switched?
7. Two parents think their baby was switched at the hospital. The mother has blood type A and the father has
blood type B and the baby has blood type AB
a. Mother’s genotype:__________________ or ______________
b. Fathers genotype: _________________ or ________________
c. Baby’s genotype:_________________ or _________________
d. Show your work with a Punnett square showing all the baby’s genotypes as a possibility:
e. Was the baby switched
Name____________________________________________
HCT II
8. Based on the information in this table, which man could not be the father of the baby? Justify your answer
with a Punnett square
Name
Blood Type
Mother
A
Father
B
Sammy
O
George
AB
The waiter
A
The cable guy
B
9. Based on the information in this table which man could not be the father of the baby? Justify your answer
with a Punnett square.
Name
Blood Type
Mother
O
Baby
AB
Bartender
O
Guy at the club
AB
Cabdriver
A
Flight attendant
B
10. Explain why blood type data cannot prove who the father of the baby is and can only prove who the father
is not
Name____________________________________________
HCT II
Modified True/False
(Determine if each statement is true or false. Please correct each false statement.)
11. ______ Type O blood is considered to be a universal donor.
12. ______ Agglutination is a form of blood clotting in the body.
13. ______ An individual who has no antigens attached to the membrane of their RBC are referred to as blood
type O.
14. ______ A person with blood type AB is considered to be a universal donor.
15. What is an antigen?
16. What is an antibody?
17. What happens in agglutination? Why can it be deadly?
18. A patient has type AB blood. If they received a transfusion of type B blood, predict and explain what would
happen.
19. A patient has type B blood. If they received a transfusion of type AB blood, predict and explain what would
happen.
20.Predict and explain what will happen to a patient with type O blood when they receive a transfusion from a
type A donor.
21.A patient with type A blood needs a blood transfusion. Identify the blood types that are compatible with
hers.
Name____________________________________________
HCT II
22. Identify the blood type of each sample below ( + - Clumping - = No Clumping)
Suspect 1:
Suspect 2:
Suspect 3:
Suspect 4:
A
A
A
A
RH
RH
RH
B
B
Blood Type_______
RH
B
Blood Type _______
B
Blood Type _______
Blood Type _______
If suspect 1 were injured during the crime and needed blood, what blood types could he receive?____________
If suspect 4 volunteered to donate blood, which blood types could receive his blood?______________________
If blood type O was left on a victim who would most likely be the guilty suspect?________________________
23. Complete the chart below by placing an x in the row of the recipient if they can receive blood from the donor.
Recipient
Donor
O-
OO+
AA+
BB+
ABAB+
X
O+
A-
A+
B-
B+
AB-
AB+