CH4 Tissues • Groups of cells similar in structure and function • Types of tissues • • • • __________ tissue __________ tissue __________ tissue __________ tissue Epithelial Tissue (Epithelium) • Two main types (by location): 1. Covering and lining __________ • On __________ and __________ surfaces 2. Glandular epithelia • __________ tissue in glands Characteristics of Epithelial Tissue 1.Cells have __________ —apical (upper, free) and basal (lower, attached) surfaces • __________ surfaces may bear __________ (e.g., brush border of intestinal lining) or __________ (e.g., lining of trachea) • Noncellular basal lamina of __________ and __________ lies adjacent to basal surface Characteristics of Epithelial Tissue 2.Are composed of __________ packed cells • Continuous sheets held together by tight junctions and __________ 3.Supported by a __________ tissue __________ lamina (under the basal lamina) 4.__________ but innervated 5.High rate of regeneration Classification of Epithelia • Ask two questions: 1. How many layers? 1 = __________ epithelium >1 = __________ epithelium Classification of Epithelia 2. What type of cell? • __________ • __________ • __________ • (If stratified, name according to apical layer of cells) Overview of Epithelial Tissues • For each of the following types of __________, note: • Description • Function • Location Epithelia: Simple Squamous • Two other locations • __________ The lining of lymphatic vessels, blood vessels, and heart • __________ The epithelium of serous membranes in the ventral body cavity Epithelia: Stratified Cuboidal • Quite __________ in body • Found in some __________ and __________ glands • Typically two cell layers thick Epithelia: Stratified Columnar • Limited distribution in body • Small amounts in __________, male urethra, and lining some __________ ducts • Also occurs at transition areas between two other types of epithelia Glandular Epithelia • A __________ is one or more cells that __________ and __________ an aqueous fluid • Classified by: • Site of product release—__________ or __________ • Relative number of cells forming the gland—unicellular (e.g., goblet cells) or multicellular Endocrine Glands • __________ glands • Secrete __________ that travel through lymph or blood to target organs Exocrine Glands • More numerous than __________ glands • Secrete products into ducts • Secretions released onto body surfaces (skin) or into body cavities • Examples include __________, __________, __________, and salivary glands Unicellular Exocrine Glands • The only important __________ gland is the __________ cell Multicellular Exocrine Glands • Multicellular __________ glands are composed of a duct and a __________ unit • Classified according to: • Duct type (__________ or __________) • Structure of their secretory units (tubular, alveolar, or tubuloalveolar) Modes of Secretion • __________ • Products are secreted by exocytosis (e.g., pancreas, sweat and salivary glands) • __________ • Products are secreted by rupture of gland cells (e.g., sebaceous glands) CH4 Connective Tissue • Most abundant and widely distributed tissue type • Four classes • __________ tissue proper • __________ • __________ tissue • Blood Major Functions of Connective Tissue • __________ and support • Protection • __________ • Transportation (blood) Characteristics of Connective Tissue • Connective tissues have: • __________ as their common tissue of origin • Varying degrees of __________ • Cells separated by nonliving extracellular __________ (ground substance and fibers) Structural Elements of Connective Tissue • Ground substance • Medium through which solutes diffuse between blood __________ and cells • Components: • __________ fluid • __________ proteins (“glue”) • Proteoglycans • Protein core + large polysaccharides (__________ sulfate and __________ acid) • Trap water in varying amounts, affecting the __________ of the ground substance Structural Elements of Connective Tissue • Three types of fibers • __________ (white fibers) • Strongest and most abundant type • Provides high tensile strength • Elastic • Networks of __________, __________, elastin fibers that allow for stretch • Reticular • Short, fine, highly branched __________ fibers Structural Elements of Connective Tissue • Cells • __________ active and secretory cells = “blasts” • Mature cells = “cytes” • __________ in connective tissue proper • __________ and chondrocytes in cartilage • __________ and __________ in bone • __________ stem cells in bone marrow • Fat cells, white blood cells, mast cells, and macrophages Connective Tissue: Embryonic • __________ —embryonic connective tissue • Gives rise to all other connective tissues • Gel-like ground substance with fibers and __________ __________ mesenchymal cells Overview of Connective Tissues • For each of the following examples of connective tissue, note: • Description • Function • Location Connective Tissue Proper • Types: • __________ connective tissue • Areolar • Adipose • Reticular • __________ connective tissue • Dense regular • Dense irregular • Elastic Connective Tissue: Cartilage • Three types of cartilage: • __________ cartilage • __________ cartilage • Fibrocartilage Nervous Tissue • Nervous system (more detail with the Nervous System, Chapter 11) Muscle Tissue • Skeletal muscle (more detail with the Muscular System, Chapter 10) Muscle Tissue • Cardiac muscle (more detail with the Cardiovascular System, Chapters 18 and 19) Muscle Tissue • Smooth muscle Epithelial Membranes • Cutaneous membrane (skin) (More detail with the Integumentary System, Chapter 5) Epithelial Membranes • Mucous membranes • Mucosae • Line body cavities open to the exterior (e.g., digestive and respiratory tracts) Epithelial Membranes • Serous Membranes • __________ —membranes (mesothelium + areolar tissue) in a closed ventral body cavity • __________ serosae line internal body walls • __________ serosae cover internal organs Steps in Tissue Repair • Inflammation • • • • Release of __________ chemicals Dilation of blood vessels Increase in vessel permeability __________ occurs Steps in Tissue Repair • __________ and restored blood supply • The blood clot is replaced with granulation tissue • Epithelium begins to __________ • __________ produce collagen fibers to bridge the gap • Debris is __________ Steps in Tissue Repair • Regeneration and fibrosis • The scab detaches • Fibrous tissue __________; epithelium __________ and begins to resemble adjacent tissue • Results in a fully regenerated epithelium with underlying scar tissue Developmental Aspects • Primary germ layers: __________, __________, and endoderm • Formed early in embryonic development • Specialize to form the four primary tissues • Nerve tissue arises from ectoderm • Muscle and connective tissues arise from mesoderm • Epithelial tissues arise from all three germ layers