Why do cells divide? Watch the lecture on mitosis by the “Penguin Prof” and fill out pages 1-5 as you watch: http://www.youtube.com/watch?v=65SODTL_QsA MITOSIS Write down a few examples of when this basic type of cell division occurs: 1. 2. 3. DNA Management The DNA in a cell is ____ feet long. When the cell is not dividing, the DNA is in the form of ____________________. When it is dividing, it is in the form of ______________. Why is chromatin good for times when the cell is functioning normally, and why are chromosomes good when the cell is dividing? Overview of Mitosis: Write a couple of sentences explaining what this diagram means. When does the replication of DNA occur? The Cell Cycle List the 3 phases of the cell cycle that make up interphase: ______, _____, & ______. List the two parts of the cell cycle that make up cell division: _______________ & _________________. 1 Take notes on the diagram below, writing down what happens in the three phases of interphase. Also write the names of the phases of mitosis. Chromosomes Label the structures 1 & 2 of the chromosome on the far right. Don’t worry about the different kind of microtubules the Penguin prof talks about from 7:06-9:08. You do not need to know about all these. We will call all the different kinds of microtubules spindle fibers. 1 = _______________ 2 = sister ___________ 3 = short arm 4 = long arm Pause the Penguin Prof: Chromosomes are made up coiled up chromatin. Chromatin is DNA wrapped around proteins called histones. Label the structures indicated by arrows using this word bank: DNA Histone Chromatin Chromosome 2 PHASES OF MITOSIS – restart the Penguin Prof Prophase – take notes on the diagram below describing what occurs during this phase. Label the centrosomes (same thing as the centrioles) and the nucleus. Prometaphase – take notes on the diagram below describing what occurs during this phase. All the different kinds of microtubules we will call the spindle fibers. Draw in the spindle fibers as they did not copy well. Metaphase – take notes on the diagram below describing what occurs during this phase. Label the centrosomes (centrioles), the spindle fibers, and the chromosomes. 3 Anaphase – take notes on the diagram below describing what occurs during this phase. Label the centrosomes and the spindle fibers. Draw a line that shows where the equator is located. Telophase – take notes on the diagram below describing what occurs during this phase. Label the cleavage furrow and the nucleus of one of the newly formed cells. How does the division of the cytoplasm of plant cells occur? How long does it take for cells to divide? An example of a type of cell that don’t divide at all once they reach maturity: An example of a type of cells divides when stimulated: An example of a type of cells that always divides: 4 HOW DO CELLS KNOW WHEN TO DIVIDE? Take notes on what happens at each checkpoint on the cell cycle. What happens in cell division that causes cancer? CELL DIVISION IN PROKARYOTES This is not in the video, get your info here: As they have no nucleus and only one long circular chromosome, prokaryotes divide by making a copy of the chromosome, and the membrane then pinching in to make two cells. This is called binary fission!!! Use this information and the diagram below to answer these questions. Label the two daughter cells in the diagram to the left. Is binary fission sexual or asexual reproduction? What kinds of cells reproduce through binary fission? 5 MEIOTIC CELL DIVISION – Sexual Reproduction (making sperm & egg) Watch this as an introduction: http://www.youtube.com/watch?v=kVMb4Js99tA Then fill out the packet using Crash Course #13: http://www.youtube.com/watch?v=qCLmR9-YY7o What does meiosis explain? Homologous chromosome pairs are: • Most of your body cells (somatic cells) are diploid and contain _____ chromosomes. But some cells are haploid and contain _____ chromosomes, these are ___________ and _____________ cells. • Meiosis starts with a diploid cell that duplicates its chromosomes, divides ________ times, creates _______ new cells, and all of the new cells are____________ from the others! Meiosis goes through the same stages of mitosis but twice! In the first division homologous chromosomes separate, and in the second division sister chromatids separate. DNA replicates in Interphase The phases of meiosis are described on the next page: 6 Stages of Meiosis Prophase 1- Same as mitosis except for 2 additional steps: Describe what is happening in the diagram below, use the terms crossing over & recombination. Describe what happens in each phase. Use the diagram below to help you: Metaphase I Anaphase I Independent assortment! Telophase I At this point, how many cells? ___ Are they diploid or haploid? ___________ Are they identical? _______ 7 Second Meiotic Division No DNA replication takes place. Using the diagram below to help you, describe what happens in each phase: Prophase II Metaphase II Anaphase II Telophase II At this point, how many cells? ___ Are they diploid or haploid? ___________ Are they identical? _______ Explain how crossing over and independent assortment provide genetic variation. And what is the advantage of genetic variation? 8 Using the information in the video and the diagram below, what is the difference between the production of egg cells and the production of sperm cells? 9 Compare and Contrast Mitosis and Meiosis: Mitosis Meiosis Purpose Phases Number of divisions Number of daughter cells Homologous chromosomes pair? Are daughter cells diploid or haploid? 10 Book Definition Autosome Any chromosome that is not a sex chromosome Binary fission Form of asexual reproduction in single celled organisms by which one cell divides into 2 equal cells The repeating set of events in the life of cell, consists of interphase and cell division The precursor of a new cell wall that forms during cell division and divides a plant cell into two An organelle that is composed of two short microtubules and that has an active role in cell division The region of the chromosome that holds the two sister chromatids together during mitosis One of the two strands of the chromosome that becomes visible cell division The genetic material that makes up chromosomes, a complex of proteins and DNA that are loosely coiled A structure made of histone proteins and DNA in eukaryotes, and only visible during cell division Cell cycle Cell plate Centriole Centromere Chromatid Chromatin Chromosome In my own words How will I remember it? 11 Cleavage furrow Cytokinesis Diploid Haploid Histone Homologous chromosoms Nucleosome Meiosis Mitosis The areas of the cell membrane that pinches in and eventually separates a dividing cell into two new cells, in animals. The division of the cytoplasm of a cell A cell that contains two haploid sets of chromosomes Describes a cell or nucleus that has only one set of unpaired chromosomes A type of protein molecule found in the chromosomes of eukaryotic cells but not prokaryotic cells Chromosomes that have the same sequence of genes, the same structure, and pair during meiosis One unit of DNA wrapped around a histone, found in a chromosomes A process of cell division in which the number of chromosomes decreases by half, which results in the production of sex cells In eukaryotic cells, a process of cell division that forms two new nuclei each of which ahs the same number of chromosomes as the original cell 12