Semester – I
Core – I
08MPCH01
RESEARCH METHODOLOGY
UNIT – I
1.
Research Methodology and Laboratory Techniques
1.1
Survey of Literature:
Primary sources – Journals – Periodicals – Patents letters, Communications,
notes – Secondary Sources – Titles – reviews, annual reviews – treatises –
Monographs, Text Books, Encyclopedia, Beilstein, buyers guide – Abstracts –
Subject Index, Substance Index – Author Index, formula index – Index of
Journal Article – Materials on a given topic – Information about Specific
Compound - Chemical Abstract search through loaded CDS – Aids od
Computer in Literature Survey.
1.2
Principles of Research
Observation Inference – Hypothesis Generation Testing of hypothesis
evaluation of rules, theories and modification of theories and rules. Selection
of topics – Instrumental Facility.
1.3
Internet:
Introduction to Internet – web browsers – World Wide Web – Search Engines
– Literature Survey in Chemistry – Popular Websites in Chemistry – Data base
in Chemistry.
UNIT – II
2.
Documentation Techniques:
2.1
Types of Report – Title – Abstract – Style and Conventions in Writing,
Selection of Topic.
2.2
Rough Drafting of the Article – Title, Abstract, Introduction – Literature
Review problem and time Limitations, Experimental Methods, results and
Discussion, Foot notes, Figures, Data Presentation, Tables, Sign Conventions
followed – Conclusions and Recommendations – Bibliography.
2.3
The General Format – Page and Chapter Format use of quotations foot note –
tables and figures – Applicability of the findings to common usage –
referencing – Abbreviations used.
2.4
Document Preparation using Computers – Use of Microsoft Word, Word
Perfect and other Packages for document preparation and formatting –
knowledge about TXT, DOC, PDF, PS, HTML formats.
UNIT - III
3.
Data Analysis:
3.1
True value - standard value - observed value – Error – Types of Errors –
Accuracy – Precision, Error Analysis, Minimization of Errors, Deviation from
Accurate Results - the Binomial Distribution – the Gaussian Distribution –
Mean - - Median – Deviation – from Mean and Median – student’s t-test, Ftest – Significant figures in multiplication – Division – Addition and
Subtraction – Curve Fitting method of Least Squares – Linear Regression –
Multiple Linear Regression – Slope – Intercept and Correlation Coefficient.
UNIT – IV
4.
C Programming
4.1
C-fundaments – Identifiers and Keywords – datatypes – constants and
variables – symbolic constants – operators and expressions.
4.2
Control Statements: If – else, while, do-while, for, goto, switch…case, break
and continue statements.
4.3
Arrays and Pointers – functions – call by value and call by reference –
Recursion – Structure and Union – File handling techniques – Library
Functions – Basic Structure of C – Programming.
UNIT – V
5.
C++ Programming
5.1
Basic concepts of OOPs – objects, classes, Data abstraction and encapsulation,
inheritance, polymorphism, dynamic binding, message passing – applications
of OOPs.
5.2
Classes and structure – Declaration, reference arguments, by value –
constructors and destructors – virtual functions – inheritance (simple example
only), Overloading – functional overloading, operators overloading (simple
example only) – file handling techniques – iostream file.
5.3
Examples of program to draw a circle, hexagon and sphere.
References:
1.
J. Anderson, B.H. Durston and M.Poole, “Thesis and Assignment Writing”,
John Wiley, Sydney 1970.
2.
R.Berry, “How to Write a Research Paper”, Pergoman, 1969.
3.
Ralph Berry, “The Research Project: How to Write It”, 4th Ed.,
4.
W.G. Campbell – “Form and Style in thesis Writing”, (1970), Boston M.A;
Houghton Mifflin Co.,
5.
Jerry March, “Advanced Organic Chemistry: Reactions, Mechanisms and
Structure”, (1996), 5th Ed., Wiley,
6.
James B. Hendrickson, Donald J. Cram George S. Hammond – “Organic
Chemistry”, (1970), 3rd Ed., McGraw-Hill Book Co., New York.
4.
E. Balagurusamy, “Programming in ANCI C” – Tata McGraw-Hill Publishing
Company Limited, New Delhi, 2005.
5.
E. Balagurusamy, “Object Oriented Programming with C++” – Tata McGrawHill Publishing Company Limited, New Delhi, 2003.
6.
D. Ravichandran, “Programming with C++”, Tata McGraw-Hill Publishing
Company Limited, New Delhi, 2005.
7.
K.V. Raman, “Computers in Chemistry”, Tata McGraw-Hill Publishing
Company Limited, New Delhi, 1993.
Semester – I
Core – II
08MPCH02
ADVANCED ORGANIC CHEMISRY
UNIT – I
Nomenclature:
Nomenclature of alicyclic compounds – Monocyclic, Bicyclic and tricyclic,
Heterocyclics – Compounds containing three atoms viz., Oxygen, Sulphur and
Nitrogen (three membered ring to six membered ring).
UNIT – II
Synthetic Organic Reagents and Reactions:
Modern synthetic reactions – Metal hydride reductions of aldehydes and
ketones (LiAlH4, NaAlH4, LiBH4, NaBH4). Oxidation – oxidation of alcohols,
aldehydes carbon-carbon double bonds by Chromium compounds, Manganese
compounds, Peracids and Peroxides.
Halogenation – Halogenation of carbonyl compounds, Benzylic hydrogen
bonds, Acylation – acylation of active methylene compounds (Basic and acetic
conditions), Acylation of enamines.
UNIT - III
Retro Synthesis:
Definition – TM – Retro Synthetic Analysis, FGI Synthesis, Synthetic
Equivalence, Disconnection – C–C bond – 1,1, 1,2, 1,3 one group, two
group – Equivalent. – Retro Synthesis of Aliphatic Compounds – F.C.
Reaction, Wittig Reaction, Dields Alder Reaction, Claisen Condensation,
Michal Addition (1,4), Aldol Condensation.
UNIT – IV
Phase Transfer Catalysts:
Introduction – Definition – Mechanism of PTC Reaction – Types of Phase
Transfer Catalysts – Advances of Phase Transfer Catalysts. Types of Phase
Transfer Reactions – Preparation of Phase Transfer Catalysts – Quarternary
salts, Macrocyclic ethers as PTC Tetrahexyl Ammonium Bromide – Benzyl
Triethyl Ammonium Chloride – Applications of PTC in Organic Synthesis –
Alcohols from alkyl halides – Esterifications – Benzoin condensation –
Darzen’s reaction – Oxidation – Reduction.
UNIT – V
ORD and CD:
Circular bireferenges – Circular Dichroism – Cotton effect. Types of cotton
effect curves – Axial haloketone rule – statement and its applications.
Determination of absolute configuration of ketones.
Octant rule and its
explanation. Application of octant rule on conformation and configuration of
organic and inorganic complexes.
References:
1.
R. S. Cahn and O. C. Dermer, “Indroduction to Chemical Nomenclature” 5th
Edn., Butterworths, London – Boston.
2.
“Defenetive Rules for Nomenclature of Organic Chemistry”. Taken from the
IUPAC nomenclature of Organic Chemistry 1979 Edn., Published by
Pergamon Press, Inc., New York - 10523 USA.
3.
Herbert O. House “Modern synthetic reactions” – 2nd Edn., W. A. Benjamin
INC., London – 1972.
4.
V.K. Ahhwalia – “Organic Synthesis – Special Techniques”, Renn Aggarwal –
Narosa Publishing House.
5.
E.L. Eliel, stereochemistry of carbon compounds Mc Graw Hill. (1975)
6.
I.L. Finar, Organic chemistry vol-II, 5th Ed. ELBS (1975)
Semester – I
Core – III
08MPCH03
ADVANCED APPLIED CHEMISTRY
UNIT – I
1.
Chromatography – I
1.1
HPLC:
Introduction – Column Packing Materials – Solvent – Detectors – Recorder –
Terms and Definitions used in HPLC analysis and applications.
1.2
Gas Chromatography:
Introduction – Retention Time – Retention Volume – Efficiency – Career
Gases – Preparation of Columns – Solid Supports – Stationary Phases
Detectors – Temperature Effect – Quantitative and Qualitative analysis and
applications.
UNIT – II
2.
Chromatography – II
2.1
Gel Permeation Chromatography: (GPC)
Introduction – Types of gels – Selection of gels – Gel Preparation – Drying of
gels – Packing of the Column Application of the sample – Resolution –
Detectors and Applications.
2.2
Gas Chromatography Mass Spectrometry: (GCMS)
Introduction – Separators – Carrier gas – Sample Injection – Analyzer and
Applications.
2.3
Liquid Chromatography Mass Spectrometry: (LCMS)
Introduction – Ionization – Belt Interface – Instrumentation and Applications.
UNIT – III
3.1
Nuclear Quadrupole Resonance Spectroscopy:
Introduction – Theory of NQR, NQR Spectra and Magnetic Field –
Instrumentation – Structural Information from NQR Spectra – Application of
NQR.
3.2
Photoelectron Spectroscopy:
Introduction – Types of Electron Spectroscopy – Theory of Electron
Spectroscopy -
Auger Emission Spectroscopy – Instruments for Electron
Spectroscopy – Applications of Auger Electron Spectroscopy - Electron
Spectroscopy of Chemical Analysis – Chemical Shifts in ESCA – Core
Binding Energy – Vibrational Coarse Structure of Electronic Spectra –
Applications of ESCA.
UNIT – IV
4.
Diffraction Studies:
4.1
X – Ray Diffraction:
X – rays and their generation; Crystals and the diffraction of X-rays – Laue
equations, Bragg’s Law – X-ray diffraction experiment – Powder Method,
Single Crystals methods – Principles and Uses. Intensities – R-factors and
Structure Determination. High Temperature Powder diffraction. Effect of
crystal size on powder pattern – Particle size measurement.
4.2
Neutron Diffraction – Location of light atoms in the presence of heavier ones,
distinction between atoms with similar atomic numbers, transition in magnetic
crystals.
4.3
Electron Diffraction – by gases, by crystals
UNIT – V
5.
Desalination of Water:
Sea water as a source of drinking water – Desalting – Electro dialysis method,
reverse osmosis method, Industrial water treatment – removal of iron, silica,
dissolved oxygen, water for laundry work – water for boiler use – removal of
slime and algae from water. Deaeration and Deoxygenation of water, chemical
deoxygenation of water, clarification of water – coagulation of water Flocculators.
References:
1.
H. Kaur – “Spectroscopy”, (2005), Pragati Prakashan, Meerut,.
2.
Colin. N. Banwell and Elaine M.McCash – “Fundamentals of Molecular
Spectroscopy”, 4th Ed., Tata McGraw-Hill Publishing Company Ltd.- New
Delhi, 2000.
Jag Mohan – “Organic Spectroscopy – Principles and Applications”, (2007),
3.
2nd Ed., Narosa Publishing House.
4.
P.S. Kalsi – “Spectroscopy of Organic Compounds”, (2004), 6th Ed., New Age
International Publishers.
5.
Robert Brawn – “Introduction to Chemical Analysis”, McGraw-Hill Book
Company.
6.
Christian and James – “Instrumental Analysis”, 2nd Ed.
7.
Srivastava, V.K. Srivastava – “Introduction to Chromatography”, S.Chand &
Company.
8.
Jag Mohan – “Organic Spectroscopy Principles and Applications”, 2nd Ed.,
Narosa Publishing House.
9.
A.F.Wells – “Structural Inorganic Chemistry”, (1962), 3rd Ed., Oxford
University Press,
Antony R.West, John – “Solid State Chemistry and its Applications”, Wiley &
Sons, New York.
10.
11.
B.K. Sharma, H.Kaur – “An Introduction to Environmental Pollution”, Goel
Publishing House.
Semester – I
Core – IV
08MPCH 04
MODERN APPROACH TO CHEMISTRY
UNIT – I
1.
Bio molecules
1.1
Protein
Biologically important protein, sources of protein – Biological functions of
protein – peptide bond formation – poly peptide chains – classification of
protein – properties of protein – Tests for protein
1.2
Nucleic acid
Nucleic acid –l occurrence – General structure of Nuclei acid – Types of
Nucleic acid – Nucleotide – Nucleosides – Functions of DNA and RNA –
comparison of DNA and RNA. Biological functions of Nucleic acid.
1.3
Lipids
Introduction, occurrence, sources fat and Atherosclerosis, Fat deposits,
Brownfat, component of lipids. Glycerol – structure of lipids – structure of
fatty acids – classification of fatty acids. Classifications of lipids – simple
lipids – oil – wax – phospholipids glycolipids and derived lipids.
UNIT – II
2.1
Methods in Microbiology
Methods of sterilization, culture media, pure culture methods, staining of
bacteria, counting cells.
2.2
Bacterial diseases of man
Airborne diseases, food borne, water borne diseases, and soil borne, sexuallytransmitted and contact diseases – control of micro organism – physical and
chemical control – chemotherapeutic agents.
Industrial production of penicillin, streptomycin and cephalosporin.
UNIT – III
3.
Polution:
3.1
Air Pulution:Introduction - Mechanism of distribution – primary, secondary
and tertiary dispersion, Essential and non-essential Air pollution & Control
Introduction – classification of air pollutants – air pollutants and their effects –
Acid rain – photochemical smog – particulates – characteristics and
biochemical effects of some air pollutants and their effects – Air pollutants
from industrial and other sources. Air pollution control.
3.2
Trace Elements – Pollution and Control
Trace elements, physiological role of trace metals, trace elements in marine
environment,
heavy
metals,
Industrial
uses
and
pollution
sources,
Environmental levels, Ecological effects, Bio-chemical effects, Toxicology,
environmental fate, control and treatment of the following trace element of the
following trace elements: Hg, Cd, Pb, Cr, As, Ni, F, Co and Mn.
UNIT – IV
4.
Mathematics for Chemists:
Functions – constant and variables function – classification of functions –
single and many valued function, Explicit and Implicit functions – odd and
even functions – inverse functions – Differentiation – Definition – Product
Rule – Functions of Function rule – Integration – Definite integral – Methods
of Integration – substitution – Integration by parts – Properties of definite
integrates – vector and scalar products, inner product and cross product.
UNIT – V
5.
Human Resource Management:
Definition, objectives of Human Resources, Human Resource Policies, Human
Resource Planning, Recruitment and Selection, Placement, Promotion,
Training and Development. On the job Training, Off the job Training and
Development. Performance Evaluation, Wage and Salary Administration,
Rewards and Labour Welfare.
References:
1. P.D. Sharma, -“Microbiology”, (2000) Rastogi Publications 2nd edn., Meerut.
2. M.J. Pelezar – “Microbiology”, (2004) Tata Mcgraw Hill publications,
New Delhi.
3. A. Mani, Dr. A.M. Selvaraj, Dr. L.M. Narayanan, Dr. N. Arumugam –(2004)
“Saras publication” Kanyakumari.
4. Dulsy Fatima, R.P. Meyaan pillai, N. Arumugam – (1994) Saras Publication
Ist ed. Kanyakumari.
5. B.K. Sharma, H. Kaur –Environmental chemistry 3rd ed. (1996-97) Goel
publishing house, Meerut.
6. S.S. Dara – “A Textbook of Environmental chemistry and pollution control Ist
ed. S.Chand & Co. Ltd.
7. J.L. Jain – (2001) “Fundamentals of biochemistry” 5th ed., Sulthan chand,
New Delhi.
8. A.L. Lehninger and D.L. Nelson – “principle of biochemistry” 2nd ed. CBS
publication.
9. M.L. Chatterjee – “A Textbook of Medical and Biochemistry” Vth ed. Jayplee
brothers medical publishers pvt. Ltd., New Delhi.
10. Bhupendra Singh – “Mathematics for Chemists”, Pragati Edition.
11 S. Narayanan, T.K. Manicavachagam Pillay – “Calculus”, Vol – I, II, III,
S. Viswanathan (Printers & Publishers).
12. Edwin Flippo – “Principles of Personnel Management”, Tata McGraw Hill
13. .G. Nair Latha Nair – “Personnel Management and Industrial Relations”,
Chand & Co.
14. Dr.P. Subba Rao – “Human Resource Management” Himalaya Publishing
House.