Chemistry 532 – Lectures – Fall 2008
Instructor:
Textbook:
Office:
Dr. Erach R. Talaty
“Organic Chemistry” by Vollhardt and Schore, 5th Edition
Room 304B McKinley Hall
Week Starting
Students should
review these topics.
Topic
SN1, SN2, E1, E2 Reactions
Conformations of Alkanes and Cycloalkanes – Review
Chapter
6, 7
4
Aug. 22, 25
Radical Reactions
3
Sept. 1, 8, 15
Alkenes and Alkynes: Synthesis and Reactions
11, 12, 13
Sept. 22, 24
Spectroscopy: Infrared, NMR, Mass Spectrometry
(Mostly covered during lab)
10, 11
Oct. 6, 13
Alcohols and Ethers
Oxidation-Reduction and Organometallic Compounds
Conjugated Unsaturated Systems; UV/Visible Spectroscopy
8, 9
8, 12
14
Oct. 20, 27
Aromatic Compounds and their Reactions
Arenediazonium Salts
15, 16
Nov. 3, 10, 17
Aldehydes and Ketones: Nucleophilic Addition to the
Carbonyl Group
Aldehydes and Ketones: Aldol Reactions
17
Nov 24, Dec. 1
Carboxylic Acids and their Derivatives
Beta-Dicarbonyl Compounds
Amines
19, 20
23
21
Dec. 8
Carbohydrates
Amino Acids and Proteins
24
26
Dec. 10
Last Lecture
18
FINAL EXAMINATION: MONDAY, DECEMBER 15, 8:00-9:50 A.M.
Grading Formula:
Lecture
Laboratory
- 70%
- 30%
For Lecture Portion: Three examinations
*Standard ACS Exam (during lab)
Final Exam
3X20% = 60%
= 20%
= 20%
All examinations are cumulative, that is, each exam will cover all material from the first day of class
until the lecture before the exam.
*The ACS (American Chemical Society) exam is a cumulative exam covering both CHEM 531 and
532 and is nationally normed. It is a multiple choice exam which will be given Dec. 11 during lab.
Chemistry 532 – Fall 2008
ORGANIC CHEMISTRY LAB
TEXT: “Experimental Organic Chemistry”, Gilbert and Martin, 2006, Fourth Edition
Synthesis and Lab Techniques in Organic Chemistry
8/28
CHECK-IN – Lab safety, organization and procedures, library skills/Science
Librarian, Ch 26.
EXPERIMENT 1
9/4
IR and NMR SPECTROSCOPY – Theory, use of instrumentation, and
interpretation of spectra, pp 233-293.
EXPERIMENT 2
9/11
UNKNOWNS – Identification of compounds, pp 817-888.
EXPERIMENT 3
9/18
ADDITION REACTIOINS OF ALKENES – Synthesis of 1, 2-cyclohexanediol
from cyclohexene, handout and pp 327-376.
EXPERIMENT 4
9/25
10/2
10/9
MULTISTEP ORGANIC SYNTHESIS – Preparation of the antibiotic
sulfanilamide via electrophilic aromatic substitution of a protected aniline, pp
690-708.
EXPERIMENT 5
10/23 REACTIONS OF CARBONYL COMPOUNDS – Wittig reaction, pp 587-589,
10/30 564-568; Crossed aldol reaction, pp 603-608.
EXPERIMENT 6
11/6 GRIGNARD REAGENTS: CARBOXYLIC ACID FORMATION –
11/13 Preparation of benzoic acid from bromobenzene, pp 623-631, 633, 639-642.
11/13 LABORATORY EXAMINATION AND MAKE-UP.
EXPERIMENT 7
11/20 REDUCTIONS OF IMINES: PREPARATION OF AMINES – NaBH4
reduction of N-Cinnamyl-m-nitroaniline, pp 551-553, 559-566.
12/4 CLEANUP AND CHECKOUT.
12/11 STANDARD ACS EXAM
Grading Scale for Laboratory
Experiments:
Laboratory Examination:
105 points
45 points