SOLUTIONS FOR MEIOSIS AND GENETICS EXAM 1. (a) A2 BIO RICHARD LLOPIS-GARCIA (i) Meiosis as number of chromosomes halved; 1 (ii) Mitosis as number of chromosomes stays the same; 1 (b) Feature Female offspring Male offspring Crossing over Independent segregation of chromosomes x Random fusion of gametes 2 (c) Offspring will contain a single b allele only; 1 [5] 2. (a) Homozygous (for alleles concerned); 1 (b) 24 – 26cm; 1 (c) (i) Single characteristic controlled by many genes/more than one gene; 1 (ii) Many lengths/wide range of lengths/phenotypes; in F2 generation; 2 (i) Two different groups/produce intermediate offspring; 1 (ii) Each parent shows variation although genotype the same; 1 (i) A piece of DNA which codes for a single protein/polypeptide; 1 (ii) A particular form of a gene; 1 (i) w; 1 (ii) Ww; 1 (i) The same/0.7 and 0.3; 1 (ii) Hardy-Weinberg equation given correctly as p2 + 2pq + q2 (= 1); understands p = 0.7 and q = 0.3; percentage of heterozygotes = 42 3 (d) (e) (f) (g) [15] 3. (a) mitosis meiosis neither All four answers correct, 2 marks At least two answers correct 1 mark (b) Four haploid cells, each with two chromosomes; Correct combinations of chromosomes; City of Bath College 2 2 1 SOLUTIONS FOR MEIOSIS AND GENETICS EXAM (c) A2 BIO RICHARD LLOPIS-GARCIA 8 chromosomes/4 pairs; 1 [5] p 44. (a) (b) (i) DNA will be halved / less / DNA doubles / increases / there are 2 groups of nuclei; 1 (ii) Group with most DNA is before division; in first division amount of DNA halved; second division halves this again; three different amounts of DNA / quoted figures; 3 Random segregation / independent assortment; allows different combinations DNA / chromosomes; OR (c) (d) (e) crossing over / chiasmata; allows mixing of / swapping / recombination of DNA / mixing alleles / genes / exchange of parts of chromatids / chromosomes; 2 (i) Phosphate / phosphoric acid / P ; 1 (ii) Hydrogen (bond); 1 (i) 5; 1 (ii) 3; 1 Fragment 14 / 13; single base represents smallest / lightest piece of DNA; smallest piece moves furthest / fastest; 3 [13] 5. x x ; 1 ; 1 x ; 1 x ; 1 x x x x [4] 6. (a) (i) Alike both have phosphate/phosphoric acid/PO4; bases/named bases/accept letters; nucleotides; pentose sugar; Different DNA deoxyribose; DNA thymine; DNA double stranded; DNA larger/longer; DNA one form RNA 3 types; City of Bath College MAX. 5 2 SOLUTIONS FOR MEIOSIS AND GENETICS EXAM (ii) A2 BIO RICHARD LLOPIS-GARCIA Alike H bonds break/DNA unwinds/DNA unzips; between (complementary) bases; complementary nucleotides/bases added/DNA acts as template; same, correctly named, enzymes e.g. polymerase; Different uracil/thymine used; all copied or only section copied respectively; one strand used transcription, two in replication; DNA/mRNA produced; enzymes that are different, correctly named; (b) (c) Only some genes transcribed; only one strand transcribed; different protein/enzyme required by different cells; intron ref/some DNA does not code/non sense codes/junk DNA; stutter sequences/repeat DNA; MAX. 6 MAX.2 Crossing over/chiasmata; new combinations of genes/alleles on chromosome/chromatid; independent assortment/alignment/clear description; new chromosome combinations; 4 [17] 7. (a) Event Division I / II 1 2 3 4 I I II I Phase (anaphase, metaphase, prophase or telophase) telophase prophase anaphase metaphase One mark per row;;;; (b) 3; 4 1 [5] 8. (a) One form of a / the same gene; 1 (b) Probability (girl with cystic fibrosis) = 1 in 8 / 1/8 / 0.125 / 12.5%;; = 2 marks Prob. Of cystic fibrosis = ¼ / 0.25 / 25% and P girl = ½ / 0.5/ 50%; = 1 mark 2 Chiasma formation / crossing over; Random / independent assortment / segregation; [Ignore: Ref to stages] [ Reject: Mutation] 2 (c) [5] City of Bath College 3 SOLUTIONS FOR MEIOSIS AND GENETICS EXAM 9. (a) A2 BIO RICHARD LLOPIS-GARCIA 1. Chromosomes shorten/thicken/condense; 2. Chromosomes associate in homologous/(described) pairs / formation of bivalents / tetrads; 3. Crossing-over / chiasma formation; 4. Join to spindle (fibres) / moved by spindle;(*) 5. (At) equator/middle of cell;(*) 6. (join via) centromere / kinetochore;(*) 7. (Homologous) chromosomes move to opposite poles / chromosomes separate/move apart; (ALLOW ‘are pulled apart’) 8. (Pairs of) chromatids separated in 2nd division; (*) OR “ independent assortment” unqualified = 1 mark max 6 (b) 1. Crossing-over; [IGNORE any wrong ref. to timing] 2. Independent/random assortment/orientation/segregation of (homologous) chromosomes in meiosis I; 3. Independent/random assortment/orientation/segregation of chromatids in meiosis II; + Any three from: 4. Different adaptations / some better adapted; 5. Some survive / example described; 6. To reproduce; 7. Pass on gene/allele; 8. Allows for changing environment/different environment/example described;max 5 (c) (i) 21; (ii) 1. T. aestivum has 2 copies of each type of chromosome/is diploid; 2. T. aestivum’s chromosomes can form bivalents/can assort in meiosis/ can produce haploid gametes; 3. T. aestivum’s gametes receive a copy of every chromosome/ receive all the genetic information; [ACCEPT converse argument for hybrid plants] 1 3 [15] City of Bath College 4