Introduction to Immunology (Biol 321)
1. Purpose of the course: to give students an understanding of not only HOW the
immune system works, but also WHY the immune system functions in the
manner in which it does.
2. INSTRUCTOR: Lorraine Cramer, Ph.D.
A. Address :
822D Mary Ellen Jones Bldg
CB#7290
116 Manning Dr.
Chapel Hill, NC 27599
Email: lcramer@med.unc.edu
1) Directions to Dr. Cramer’s office :
a. My office is on the 8th floor of the Mary Ellen Jones Building (MEJB).
MEJB is on the west corner of West St. and Manning Dr. opposite the
Dental School and caddy-corner from the hospital.
b. My office is in room 822D. Enter the front of the building! When you exit
the elevator, turn RIGHT and you will see my office block in front of you
(the room numbering on the 8th floor is not that straightforward).
c. There is a parking garage on Manning across from the hospital if you
need to drive and park.
d. Please feel free to make an appointment to come and talk with me..
2) I offer office hours on Mon/Tues from 10-12 or we can schedule meetings
prior to class.
B. Sarah Jacobs, Ph.D will be helping me teach this course this semester.
Her Address is:
Lineberger Comprehensive Cancer Center
450 West Drive,CB#7295, Room 31-306
University of North Carolina-Chapel Hill
Chapel Hill, NC 27599-7295
Email: sarah_jacobs@med.unc.edu
Sarah will have an office hour on Friday's in room 31-306 in the Lineberger
Comprehensive Cancer center from 3-4pm. Feel free to contact me via email
to meet at a different time.
Directions: The lineberger building is on West Dr. next door to Mary Ellen
Jones and across the street from the Cardinal Parking deck. Take the elevator
up to the third floor and proceed to the wing father away from West Dr. This is
where the 31-000 rooms are. Take a left and go down the hall way on the
right. Room 31-306 will be the third door on your right.
Email is the best way to get in touch with either of us.
3. Information on class structure:
A. A summer class is a very intensive course; we meet every day for two hours.
Attendance is required (two days grace-it is up to you to get information from
missed days as well as to let me know why you missed).
B. Textbook: Basic Immunology: Functions and Disorders of the Immune System,
4th edition, Abbas, Lichtman.
C. We are going to cover most of the book. The purpose of the course is to
understand the basics of the immune system.
1) We will be using the textbook as notes. Literally.
2) We will be assigning reading from the book as homework.
4. Assignments:
A. Poll Everywhere Question (25 points): Each student will post individual
answers to questions.
1) For some questions, students will work in small teams to answer class
questions. Points will be assigned on the number of correct answers out of
total questions asked.
2) You will need to have a computer or access to the internet via phone,
tablet, etc.
B. One Peerwise question per chapter (25 points): We will be using Peerwise to
write multiple choice questions for each chapter.
1) They will be due the day after we finish each chapter.
2) You will have to write a question, explain why the answer is correct AS
WELL AS why the other answers are wrong.
3) Question will be graded on quality, difficulty and feedback of other
student’s questions.
C. Homework Assignment-Structural Throwdown: 20 pts.
1) Each small group will be randomly assigned a immunological process that
you will have to illustrate process of action in class.
2) Creativity (as well as accuracy and detail) will be rewarded!
3) There will be a grading rubric given to class for group grading. It should
demonstrate all structural features that contribute to the functionality of the
process.
4) The homework will be judged by small groups and a team of experts (AKA
graduate students from the Immunology Department).
5. Quizzes and Final Exam
A. There will be two in class 30 minute quizzes and one final exam (the University
allows 3 hours for the final exam). Each quiz is worth 50 points and the final
will be worth 100 points.
6. The UNC honor code
A. I expect you to know and understand the UNC honor code. If you do not know
or understand it, please go the following link and read the honor code
carefully.
http://instrument.unc.edu/
B. No cell phones or other electronic devices will be allowed to be used during
the quizzes or exams. If you are caught cheating, your exam will be taken and
you will receive no credit and be put to the UNC Honor Court.
7. Total points for class:
Total points:
Poll Everywhere questions
25 points
Peerwise questions
25 points
Group Project
20 points
Quiz (50 points each)
100 points
Final exam
100 points
_________________________________________________________
270 points
8. GRADING AND GRADING POLICY:
A. Grades will be based on percentage of total points.
94-100% A
90-93.99% A87-89.99% B+
84-86.99% B
80-83.99% B77-79.99% C+
74-76.99% C
70-73.99% C67-69.99% D+
64-66.99% D
60-63.99% DBelow 60% Failing
Lecture Schedule for SSII: Biology 321
June 20
Introduction to Immunology: Overview of Innate and Acquired Immunity
Chapter 1
June 24
June 25
Innate immunity
Chapter 2
June 26
Antigen capture and presentation
Chapter 3
June 27
July 1
July 2
July 3
Antigen Recognition
Quiz 1 (30 min. All material covered so far in class)
Cell mediated immune response and effector mechanisms
Chapter 4
Chapter 5 and
6
July 4
July 8
July 9
Humoral immune responses and effector mechanisms of humoral immunity Chapter 7 and
8
July 10
July 11
July 15
Quiz 2 (30 min quiz: All material covered so far in class)
Immunological tolerance and autoimmunity
Chapter 9
July 16
Hypersensitivities
Chapter 11
July 17
Congenital and acquired immunodeficiency
Chapter 12
July 18
Immune responses against tumors and transplants
Chapter 10
July 22
July 23
Structural Throwdown- group presentation
July 24
July 25
Reading day
July 26
3pm-6pm
Final Exam Cumulative worth 100 points
Poll Everywhere Question (25 points): Work in small teams to answer class
questions, as well as individual answers to question. Points will be assigned on the
number of correct answers out of total questions asked. You will need to have a
computer or access to the internet via phone, tablet, etc.
One Peerwise question per chapter (25 points): We will be using Peerwise to
write multiple choice questions for each chapter. They will be due the day after
we finish each chapter. You will have to write a question, explain why the answer
is correct AS WELL AS why the other answers are wrong. Question will be
graded on quality, difficulty and feedback of other student’s questions.
Homework Assignment-Structural Throwdown: 20 pts.
Each small group will be randomly assigned a immunological process that you will
have to illustrate process of action in class. Creativity (as well as accuracy and
detail) will be rewarded! There will be a grading rubric given to class for group
grading. It should demonstrate all structural features that contribute to the
functionality of the process.