DNA Replication Notes
First, think about these…
1. When does DNA replication occur?
2. Where do the raw materials for DNA replication come from?
3 major steps involved in DNA replication:
1. Unwind/unzip DNA
2. Add in complimentary bases
3. Bond nucleotides together to re-form backbone
(3.5).
The proteins/enzymes responsible:
A. Helicase –
B. Binding Proteins
C. Primase – Initiates replication by laying down RNA “primer” (replaced by DNA
later)
D. DNA polymerase –
E. DNA ligase –
Other terms:
Bidirectional
Okazaki fragments
Leading, lagging strand
Your task:
Part 1– using the provided diagram and each of the terms above, explain the steps
involved in DNA synthesis. Use the correct proteins/enzymes when necessary to explain
HOW something is done.
Part 2 – Label the diagram’s “A-E labels” with the structure that each is pointing to
and/or the enzyme that is acting there to accomplish some job.
http://www.ncc.gmu.edu/dna/repanim.htm
http://www.johnkyrk.com/DNAreplication.html