Name_____________________
Biology 1, Ms. Desfossé
DNA Structure & Replication/TRANSCRIPTION/TRANSLATION PRACTICE
TEST
1. DNA is
a. Nucleic acid
b. Carbohydrate
c. Protein
d. Lipid
2. DNA is a polymer made up of many smaller monomers. The monomer of DNA is
a. RNA
b. Nitrogenous base
c. Nucleotide
d. Phosphate
3. What type of reaction links together the DNA backbone
a. Condensation reaction
b. Dehydration reaction
c. Hydrolysis reaction
d. A and B
4. Which of the following descriptions best describes the image below:
a.
b.
c.
d.
Purine
Pyrimidine
Adenine
Guanine
5. Which of the following are ALL pyrimidines?
a. Guanine, adenine, and cytosine
b. Uracil, thymine, and guanine
c. Adenine, cytosine, and thymine
d. Cytosine, thymine, uracil
6. DNA is double stranded. What type of bond holds the two strands of DNA together?
a. Phosphoacetyl bonds
b. Hydrogen bonds
c. Phosphodiester bonds
d. Nitrogenous bonds
7. Which scientist is responsible for doing the laboratory work (X-ray crystallography) that
led to the discovery of the 3-D structure of DNA?
a. Erwin Chargoff
b. James Watson
c. Rosalind Franklin
d. Francis Crick
8. In a DNA double helix, a region along one strand of DNA has the following sequence:
5’- GCCTAATC-3’
What is the complementary sequence?
a. 3’-GCCTAATC-5’
b. 5’-CGGATTAG-3’
c. 5’-CGGAUUAG-3’
d. 3’-CGGATTAG-5’
9. Look at the following DNA strands. Which one is going to be harder to pull apart
(separate the two strands)? Note that only one strand of the doubled stranded DNA is
shown. You should be able to extrapolate what the other strand would be.
a. 5’-TTCC-3’
b. 5’-AATC-3’
c. 5’-GGCG-3’
d. 5’-AGCG-3’
10. Look at the following sequence in a nucleic acid: 5’-GCUA-3’ What kind of nucleic acid is
this?
a. DNA
b. RNA
c. Protein
d. Unable to tell from the information given
11. If a DNA molecule contains 40% adenine, what are the percentages of each of the other
nitrogenous bases?
a. 20% cytosine, 20% adenine, 20% guanine
b. 20%thymine, 40% guanine, 40% cytosine
c. 40% thymine, 10% guanine, 10% cytosine
d. 40% uracil, 10% guanine, 10% cytosine
12. Transcription goes from
a. RNA to DNA
b. DNA to DNA
c. Protein to RNA
d. RNA to protein
e. DNA to RNA
13. Translation goes from
a. RNA to DNA
b. DNA to DNA
c. Protein to RNA
d. RNA to protein
e. DNA to RNA
14. For the following DNA template strand, what is the mRNA that would be produced?
5’ – CTA TTT CAA CGC TCG GCG TAG CAT- 3’
a.
b.
c.
d.
3’ – GAT AAA GTT GCG AGC CGC ATC GTA – 5’
3’ - CTA TTT CAA CGC TCG GCG TAG CAT – 5’
3’ – GAU AAA GUU GCG AGC CGC AUC GUA – 5’
5’ - GAU AAA GUU GCG AGC CGC AUC GUA – 3’
15. For the following DNA template strand, what is the polypeptide that would be produced?
5’ – CTA TTT CAA CGC TCG GCG TAG CAT- 3’
a.
b.
c.
d.
Met – Leu – Arg – Arg – Ala – Leu – Lys
Asp – Lys – Val – Ala – Thr – Arg – Ile – Val
Met – Lys – Arg – Gln – Cys – Leu – His
Met – Pro – Trp – Arg – Arg – Phe - Ala
16. What allows us to put DNA from one species, like a jellyfish, into another species, like a pig?
a. Pigs and jellyfish have the same genes
b. Pigs and jellyfish make the same proteins
c. The genetic code is universal.
d. All DNA is made up of the same components and each codon stands for the same amino
acid regardless of the species.
e. Both C and D
17. In translation, which of the following is responsible for bringing amino acids to the ribosome to
be added to the polypeptide chain?
a. rRNA
b. mRNA
c. tRNA
d. RNA polymerase
e. Large subunit of the ribosome
18. A tRNA has the following anticodon: 3’-GCU-5’. What amino acid does it code for?
a. Ala
b. Arg
c. Ser
d. Leu
e. Phe
19. What amino acid does the “Start tRNA” carry?
a. Ala
b. His
c. Met
d. Trp
e. Phe
20. What kind of bond is formed between amino acids in order to make a polypeptide chain?
a. Phosphodiester bond
b. Peptide bond
c. Hydrogen bond
d. Ionic bond
e. Metallic bond
21. The picture below depicts mRNA being transcribed from a DNA molecule. Which DNA strand is
the coding strand?
a. The top DNA strand
b. The bottom DNA strand
c. Both strands are coding
d. Neither strand is coding
e. Unable to determine from the information given
REFERENCE SHEET