Special Topics in Biotechnology 1. Course Objectives: In this course, we will explore the fundamental issues of biotechnology. What is biotechnology and how did it come about? How is biotechnology done and how is it being used today? What are the applications of biotechnology? Finally, what are some of the issues that biotechnology raises about the role of science and technology in society? 2. Instructor: Dr. Shu-Jen Chen Office number: Room 705 of the Building of Chemical Engineering Phone number: Ext. 5114 Office hours: Thursday am. 10:30- 11:50 or make appointment after class or by phone 3. Course description (1) Basic Concepts in Biotechnology (1 week) (2) Introduction to Living Things (1 week) (3) Biochemical Basis for Biotechnology (2 weeks) (4) Enzyme Engineering (2 weeks) (5) Introduction to Microbiology(1 week) (6) Bioenergetics and Metabolism (2 week) (7) Central Dogma of Life (2 weeks) (8) Regulation of Gene Expression (1 weeks) (9) Genetic Engineering (1 weeks) (10) Fermentation Engineering (3 weeks) (11) Applications of Biotechnology (1 weeks) (12) Term Paper Report and Examination (1 weeks) 4. Grading Evaluation Form Percentage Note Ordinary mark Quiz or homework 20% The quiz will be held 20 min. before finishing class (open book). Midterm exam Written examination 40% Open-book Term paper (presentation) 40% Written report: 20% Presentation: 20% (power point format) Final exam 5. Suggested Reading 1. Bourgaize, D. “Biotechnology: Demystifying the Concepts”, Addison Wesley Longman, Inc., San Fransisco, CA. 2000. 2. Barnum, S. R. “Biotechnology: An Introduction”, Wadsworth Publishing Company, CA. 1998. 3. Glick, B. R. and Pasternak, J. J. “Molecular Biotechnology: Principles and Applications of Recombinant DNA”, 2nd edition, American Society for Microbiology, Washington, DC. 1998. 4. Smith, C. A. and Wood, E. J. “Molecular Biology and Biotechnology”, 1st edition, Chapman & Hall Limited. 1991. 5. Nelson, D. and Cox, M., “Lehninger Principle of Biochemistry”, 3rd edition, Worth Publishers, New York, NY. 2000. 6. Campbell, M. K., “Biochemistry”, 3rd edition, Harcourt, Inc. 1999. 7. Shuler, M. L. and Kargi, F. “Bioprocess Engineering: Basic Concepts,” 2nd ed., Prentice Hall. 2002. 8. Blanch, H. W., and Clark, D. S., “Biochemical Engineering,” Marcel Dekker. 1996. 9. Bailey, J. E. and Ollis, D. F., “Biochemical Engineering Fundamentals,” 2nd ed., McGraw-Hill. 1986. 10. 田蔚城主編, “生物技術的發展與應用”, 九州圖書文物有限公司, 台北, 台灣, 1997. (02-23652183) 11. Assigned papers. 6. Expectations: (1) Ethical conduct in the course: Dishonest behavior will not be tolerated and documented dishonest behavior during an exam will result in a failing grade on that exam. (2) Using cellular phone is not permitted during the class period! (3) Tardiness, eating, talking, and sleeping will make me unhappy. (4) Work hard and enjoy your learning. 2