HOW CAN CANCER CELLS
BE RECOGNIZED?
NAME: _______________________________
DATE: __________________ BLOCK: _______
Purpose:
In this investigation you will explore the similarities and differences between the cell cycles of normal cells and cancer cells.
Procedure:
1. Open your Internet Browser and navigate to the following URL:
http://glencoe.mcgraw-hill.com/sites/0078695104/student_view0/unit2/chapter9/virtual_labs.html
2. Click on CELLULAR REPRODUCTION
TV/VCR
3.
Click on the TV/VCR.
a.
b.
Click on the
button on the video controller.
Watch the video about the cell cycle.
c.
Once you are done watching the video, click
to return to the biology laboratory navigation screen.
INFORMATION/STATISTICS
4.
Click
to read about cancer statistics and risk factors. Complete the VenDiagram (in the DATA section below) comparing
and contrasting the three types of cancer you have statistics on.
a.
Once you are done reviewing the information, click
to return to the biology laboratory navigation screen.
MICROSCOPES
5.
Click on the microscope sitting on the right side of the lab bench on the biology laboratory navigation screen
a. Click a picture on the Table of Contents (at the top of the screen) to get information about one of the five cell phases. Use the
forward and back pointers to move between cards. Click the up arrow to return to the Table of Contents.
b. Compare the normal lung tissue cells shown through the microscope with the cell phase pictures in the microscope.
i. Label the cells with empty label boxes below them. Decide which phase a particular cell is in.
ii. Go to the information card the corresponds to the phase of the cell cycle.
iii. Click and drag the corresponding label from the top of the information card to the label box below the cell.
iv. Repeat labeling procedure for each of the five cells.
1. Click the
button.
Incorrectly labeled cells will be highlighted yellow. Click and drag any new labels to any of the cells that you labeled
incorrectly.
After you have correctly labeled the five cells, labels will appear below the other cells in the microscopic view.
i. Count the number of cells in each phase.
ii. Record your data in TABLE #1 (below)
1. Enter the number of cells that are in each phase.
2. Calculate the percentage of cells dividing (cells in mitosis). Record this on TABLE #1 (below).
3. Calculate the percentage of cells at rest (cells in interphase). Record this on TABLE #1 (below).
iii. Examine the other tissues by clicking the Tissue Slides box and selecting a tissue sample.
iv. Repeat the labeling, checking, and recording procedures for each of these tissues.
v.
c.
d.
Click
at any time to erase your labels on the cells in the microscopic view and get a new set of lung, ovary, and stomach
tissue samples.
i.
e.
Click the
button at any time to save the placement of your labels and the present tissue samples and to
return to the biology laboratory navigation screen.
Once you are done with the microscope, click
to return to the biology laboratory navigation screen.
SLIDE CAROUSEL
6.
Click on the slide carousel to view photographs of actual lung and stomach tissues. As you progress through the slide carousel, Add
information to the VenDiagram you started previously.
a. Click a slide and drag it to the slide carousel.
b. Repeat this procedure for each of the four slides.
7.
After analyzing the tissue samples under the microscope and viewing the actual slides, answer the ANALYSIS QUESTIONS below.
c.
Click the
button to return to the biology laboratory navigation screen.
HOW CAN CANCER CELLS
BE RECOGNIZED?
NAME: _______________________________
DATE: __________________ BLOCK: _______
DATA:
TABLE #1 INTERPHASE PROPHASE METAPHASE ANAPHASE TELOPHASE
% of cells
dividing
% of cells
at rest
Normal
Lung
Cancerous
Lungs
Normal
Stomach
Cancerous
Stomach
Normal
Ovary
Cancerous
Ovary
ANALYSIS QUESTIONS:
1.
Based on your data and observations, what are FOUR differences
between normal cells and cancer cells?
______________________________________________________
______________________________________________________
3.
When studying cell division in tissue samples, scientists often
calculate a mitotic index, which Is the ration of dividing cells to
the total number of cells in the sample. Scientists often calculate
the mitotic index to compare the growth rates of different types
of tissue. Which type of tissue would have a higher mitotic index:
normal tissue or cancerous tissue? EXPLAIN.
______________________________________________________
______________________________________________________
______________________________________________________
______________________________________________________
2.
Which type of cancer shows the most aggressive growth?
EXPLAIN.
______________________________________________________
______________________________________________________
______________________________________________________
______________________________________________________
______________________________________________________
______________________________________________________
______________________________________________________
______________________________________________________
______________________________________________________
______________________________________________________
______________________________________________________
______________________________________________________
______________________________________________________
______________________________________________________