FUROSEMIDE
CLASSIFICATION
Loop diuretic
TRADE NAME(S)
Lasix
DESIRED EFFECTS
Potent and rapid diuretic; increased water excretion and
venous dilation; reduces ventral venous pressure
MECHANISM OF ACTION
Inhibits sodium and chloride reabsorption in the kidney
INDICATIONS
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Pulmonary edema
Congestive heart failure
CONTRAINDICATIONS
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Hypotension (SBP<100 mmHg)
Hypersensitivity
ADVERSE REACTIONS
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Volume depletion (dehydration)
Hypotension
Potassium depletion
Rash
Headache
Deafness
Cardiac arrhythmias
Chest pain
Allergic reactions
DRUG INTERACTIONS
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Incompatible with diazepam, diphenhydramine,
and thiamine
PRECAUTIONS
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Pregnancy
Protect from light
Give slowly to prevent transient deafness
SPECIAL CONSIDERATIONS
Patients taking furosemide may require a larger dose to
achieve desired effects in the acute setting. However, IV
doses of furosemide are not subject to first pass
metabolism making its effects greater. Cardiac
monitoring should be performed. The onset of venous
dilation is approximately 5 minutes and the onset of urine
production is approximately 10 minutes.
DOSING REGIMEN
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PROTOCOL LOCATION
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Effective 7/1/11
Adult - 20 – 40 mg slow IV push (inject over
1-2 minutes)
----------------------------------------------------------------------• Pediatric – not recommended
Respiratory Emergencies – Pulmonary Edema
Drug Index
Furosemide