MICR 202: Introductory Microbiology 2 credits Spring 2014 Course Description In this class, we will study the characteristics and importance of microorganisms with the emphasis on their identification, control, and relationships to health and disease. Course Goals 1. To give students a brief historical background of microbiology and cause them to learn how microorganisms affect all aspects of their lives, positively and negatively. 2. To evaluate classic microbiological experiments that will serve to demonstrate experimental design and data interpretation. 3. To provide students with a basic understanding of microbial cell structure and function as well as an understanding of microbial classification schemes. 4. To make students aware of the rapid growth of microbial populations and how this growth can be encouraged (beneficial microbes) and discouraged (harmful microbes). 5. To provide students with a basic understanding of microbial genetics, biotechnology, and recombinant DNA techniques allowing them to appreciate the numerous beneficial applications of microorganisms. 6. To provide students with a basic understanding of how the human body interacts with microorganisms in health and disease and to provide students with an understanding of the specific and nonspecific defense mechanisms of the human body against microbial infections. 7. To provide students with an understanding of the indispensable functions of microorganisms in the environment and industry. 8. To enhance students’ comprehension of microbiological principles through the writing of a scientific paper. Instructor Rachel Richman, MS Van Es Hall 123 Phone: (701) 231-7184 Email: Rachel.L.Richman@ndsu.edu Office hours are by appointment; however, please do not hesitate to seek assistance!! Course Information MICR 202: Introductory Microbiology Spring 2014 2 credits Class #7652 -Lecture meets Tuesday & Thursday at 11:00-11:50 A.M. in Gate City Bank Auditorium -Attendance is expected (class activities, pop quizzes, and exams cannot be made up if absent). -Lecture/video outlinesand “open-note” scheduled quizzes (post-lecture quizzes & 20 pt quizzes) will be available online at the Blackboard website (Bb) https://bb.ndsu.nodak.edu . Required Textbook Microbiology: An Introduction. Second Custom Edition for NDSU-MICR 202. Tortora, G. J., Funke, B. R., and Case, C. L. (2013) 11th edition There are copies of the textbook on reserve at the NDSU library. 1 General Education The course goals, outlined previously, are designed to meet the General Education requirements in the Science and Technology category based upon the following learning outcomes: Outcome #5: Comprehend concepts and methods of inquiry in science and technology and their applications for society. Methods of Inquiry: A number of classical microbiological experiments will be evaluated in this class. These evaluations will serve to demonstrate experimental design and data interpretation. Applications for Society: In this introductory microbiology course, the significant impacts of microorganisms on society, both good and bad, will be addressed. Students will be made familiar with the widespread use of microorganisms for biotechnology, bioremediation, and fermentation. Students also will learn about the negative impacts microbial pathogens have had, and continue to have on our society. Some microbial disease outbreaks, such as plague and influenza, will illustrate the historical significance of infectious diseases. More contemporary microbial diseases, such as AIDS, West Nile encephalitis, and E. coli O157:H7, will serve to demonstrate the continuing problems of infectious diseases in our society. Outcome #6: Integrate knowledge and ideas in a coherent and meaningful manner. Writing assignments will motivate students to assimilate microbiological principles learned in class and gathered from additional sources. Students will gain experience researching microbiological subjects utilizing scientific journals, news journals, or the internet. The writing of this paper will enhance student comprehension of lecture topics by requiring them to integrate their microbiological knowledge into a coherent manuscript. In addition to writing assignments, the overall design of this introductory microbiology class will support the integration of knowledge and ideas. The course combines both microbiological fundamentals and applications. Such a blending of theory and practice will encourage students to assimilate the information in a meaningful manner. Academic Honesty: All students taking any course in the College of Agriculture, Food Systems, and Natural Resources are under the Honor System (http://www.ag.ndsu.edu/academics/honorsystem-1). The Honor System is a system that is governed by the students and operates on the premise that most students are honest and work best when their honesty, and the honesty of others, is not in question. It functions to prevent cheating as well as penalize those who are dishonest. It is the responsibility of the students to report any violations of the honor pledge to the instructor, honor commission or the Dean of the College of Agriculture, Food Systems, and Natural Resources. All work in this course must be completed in a manner consistent with NDSU University Senate Policy, Section 335: Code of Academic Responsibility and Conduct (http://www.ndsu.edu/fileadmin/policy/335.pdf). Familiarize yourself with what plagiarism is at http://www.plagiarism.org/plagiarism-101/what-isplagiarism “All of the following are considered plagiarism: turning in someone else's work as your own copying words or ideas from someone else without giving credit failing to put a quotation in quotation marks giving incorrect information about the source of a quotation changing words but copying the sentence structure of a source without giving credit copying so many words or ideas from a source that it makes up the majority of your work, whether you give credit or not (see our section on "fair use" rules) 2 Changing the words of an original source is not sufficient to prevent plagiarism. If you have retained the essential idea of an original source, and have not cited it, then no matter how drastically you may have altered its context or presentation, you have still plagiarized.” The above information was quoted/copied from www.plagiarism.org as viewed on January 2, 2014. Students with special requirements: Any students with disabilities or other special needs, who need special accommodations in this course are invited to share these concerns or requests with the instructor as soon as possible. The instructor may ask for verification and that, plus other assistance, can be requested from Disability Services in Wallman Wellness Center 170 (231-8463). http://www.ndsu.edu/disabilityservices/. Veterans and military personnel: Veterans or military personnel with special circumstances or who are activated are encouraged to notify the instructor as early as possible. Grading (No Extra Credit Is Available for This Course) Examinations There will be three examinations worth 100 points each. Examinations may consist of multiple choice, matching, diagram identification, and true/false questions based on lecture material, videos, and reading assignments. It is your responsibility to arrive on time (11:00 a.m.) to take the examinations. If you arrive late and another student has completed and handed in an examination, you will not be allowed to take the examination. You are required to bring a scantron for each exam. They will not be provided. You will need a total of 3 scantrons for the semester. You will also need to know your student ID # as it will be needed to fill in that information on your scantron. Quizzes In addition to the three scheduled 100 point examinations, there will be 3 unannounced pop quizzes worth 10 points each during lecture (no outside resources can be used). You will not be allowed to make up any missed pop quizzes i.e. attendance is important. On the Blackboard website, there will be 3 online quizzes worth 20 points each totaling 60 points. These online quizzes will be available prior to each of the 3 formal exams and be made unavailable after that particular formal exam. It is your responsibility to take the online quiz within the time frame allotted. These Blackboard online quizzes are intended to prepare you for the upcoming lecture exam and are to be taken using your course lecture notes. On the Blackboard website, there will be a total of 12 post-lecture quizzes worth 5 points each totaling 60 points for the semester. These PL quizzes will be available weekly after Thursday’s lecture with questions that come directly from that week’s lecture material and assigned readings and are “open-note” quizzes. The dates for these post-lecture quizzes are found on page 6. They will be available for approximately 5 days only (Thursday through Tuesday). These post-lecture quizzes are intended to quiz you over the major concepts covered during that week’s lecture as well as the assigned readings. It is your responsibility to complete these during the time frame allotted. You will have two attempts to take the PL quizzes so quiz resets will not be needed if your computer crashes or your browser closes. Do not use a wireless connection to complete these. Class Activities There will also be 6 unannounced class activities worth 5 points each totaling 30 points for the semester. These are not quizzes, but rather activities that may require critical thinking, 3 group work, your opinion on a current issue, or a summary of the lecture, etc. You will not be allowed to make up any class activities i.e. attendance again is important. Writing Assignment Students will be required to write one paper worth a maximum of 20 points. Topic choices can be found on our course Blackboard site in the Assignment folder along with additional instructions. Late papers will be accepted, but one point will be deducted from the overall score for each day that they are late (due on Thursday, January 30th by 11:59pm uploaded to Blackboard Assignment folder) --after this time papers will be considered late). Prior to writing these papers, students will need to find a minimum of two related articles supporting their assigned topic. These articles can be from various sources like scientific journals or nonscientific journals such as news magazines, newspapers, the internet, or appropriate textbooks. A works cited or reference page must be included and is not counted in the 1 page length. Please use whichever citation style you feel comfortable using (MLA, APA, etc.). Review how to correctly site a website as a reference source by viewing the link provided on our course Blackboard site (NDSU’s Center for Writers: Documenting Sources). The content of the paper should be 1 full page in length with spacing at single or 1.5 lines. Normal page margins should be used (0.8-1 inch) with a 10-12 point font such as Times New Roman or Arial. Point allocation will be provided in a scoring rubric located in the Assignment folder on the Blackboard site. The writing assignment is designed to satisfy general education requirements regarding the integration of microbiological principles and ideas in a coherent and meaningful manner. In preparing this paper, students will gain experience researching microbiological subjects by utilizing scientific journals, news articles, the internet, or textbooks. This writing assignment will enhance student comprehension of lecture topics by requiring them to assimilate their microbiological knowledge into an articulate manuscript. Since this is a writing requirement, grammar, punctuation, spelling, etc. will all be involved in scoring your paper. Point Distribution: Exam 1 Exam 2 Exam 3 Bb On-line 20 pt Quizzes (3) Class Activities Pop Quizzes (3) Paper Bb Post-lecture Quizzes TOTAL POINTS 100 points (tentatively scheduled for 2/20/14) 100 points (tentatively scheduled for 4/3/14) 100 points (scheduled for 5/15/14) 60 points (available prior to each exam) 30 points (unannounced times in class) 30 points (unannounced times in class) 20 points (due January 30th, 2014 Assignment folder Bb) 60 points (weekly based on lecture notes and readings) 500 points If all grades are posted on Blackboard for an exam, pop quiz, class activity, or a writing assignment and you feel there is a discrepancy with your posted grade, you must contact me within two weeks or your posted grade will stand. It is your responsibility to hand assignments in on a timely manner, read emails sent to your NDSU account, read announcements posted on the course Blackboard site, and take exams as they are scheduled. As a student, it is your responsibility to contact me immediately if you encounter difficulties with the Blackboard site via phone or email (after work hours). 4 Final grades will be distributed as follows (THERE IS NO EXTRA CREDIT GIVEN IN THIS COURSE): Total points 450-500 400-449 350-399 300-349 <300 Percent 90-100 80-89 70-79 60-69 <60 Grade A B C D F Tentative Examination Schedule Exam 1, Thurs. 2/20/14 100 points (Ch. 1, 4, 5, 6; plus additional topics, videos, reading) Exam 2, Thurs. 4/3/14 100 points (Ch. 7, 8, 9, 10; plus additional topics, videos, reading) Exam 3, Thurs. 5/15/14, 8:00-10:00 am, 100 points (Ch. 14, 16, 17, 27; plus additional topics, videos, reading) Missed Examinations Students will be expected to take exams on the days designated by the instructor. Exceptions will only be made for legitimate reasons (e.g. illnesses, either personal or immediate family) and written documentation (e.g. a doctor’s excuse) will be required. It is your responsibility to make every effort possible to contact the instructor PRIOR to missing an examination. If an exam is missed due to class cancellation by the university, the exam will be given at the next regularly scheduled class period. Technology Please turn off cell phones prior to the start of class unless you are expecting an extremely important call (turn ringer to silent). There will be no calculators, cell phones, iPods, MP3 players, etc. allowed during any examination or quiz. 202L Introductory Microbiology Laboratory (Van Es 105 or 107) If you are having trouble registering for a lab section, please see Ms. Janice Haggart (Van Es 124, 231-8345 or email Janice.Haggart@ndsu.edu). Labs will meet briefly during the first week of the semester so it is necessary to attend the lab section you are enrolled in. Lab manuals are available at the NDSU Bookstore. Gently used lab kits can be purchased the first day your lab section meets. New lab kits can be purchased at the NDSU Bookstore. 5 Micr 202 Tentative Class Schedule for Spr 2012 Course Introduction Date Bb quizzes Assigned Textbook Reading Clinical Case Text Reading p. 3 applications, 6-8 spontaneous gen & biogenesis, 15-21 microbes & human welfare p. 76 comparing, 87 table 4.1,100 table 4.2, 108 euk summary Clinical Case: A Simple Spider Bite? Starts on p. 2 Jan. 14 Jan. 16 Jan. 21 Jan. 23 #1 (5 pts.)* Jan. 28 Jan. 30 #2 (5 pts.)* Feb. 4 Feb. 6 #3 (5 pts.)* p. 123 Fig 5.11, 134 applications,142 clinical focus, video outline for ULE #3 Ch. 6 Microbial Growth Feb. 11 Feb. 13 #4 (5 pts.)* p. 160-161 biofilms, p. 171-177 direct vs indirect measurements Clinical Case: Glowing in the Dark Starts on p.154 Additional Lecture Day Feb. 18 Exam 1** Bring Scantron Feb. 20 Ch. 7 Control of Microbial Growth Feb. 25 Feb. 27 #5 (5 pts.)* p. 182-184, 191-192 Principles, Types 192-199 Clinical Case: A School Epidemic Starts on p.182 Ch. 8 Microbial Genetics Mar. 4 Mar. 6 #6 (5 pts.)* p. 210 fig 8.2, 223 mutation, 231-239 transf, conj, transduction, transp Mar. 11 Mar. 13 #7 (5 pts.)* p. 250, 251 PCR/Reversetranscription PCR, 265 clinical focus, 266 issues Clinical Case: No Ordinary Checkup Starts on p.245 p. 281-29(include applications p. 282) Clinical Case: Full-Flavor Outbreak Starts on p. 273 Ch. 1 The Microbial World and You Ch. 4 Functional Anatomy of Prokaryotic and Eukaryotic Cells Ch. 5 Microbial Metabolism **Writing Assignment Due Jan. 30 via Bb (see p.3-4 of syllabus/Blackboard site)** Ch. 9 Biotechnology and DNA Technology Clinical Case: Infection Detection Starts on p. 76 Online #1 (20 pts.) SPRING BREAK MARCH 17-21 Ch. 10 Classification of Microorganisms Additional Lecture Day Mar. 25 Mar. 27 Apr. 3 Ch. 16 Innate Immunity: Nonspecific Defenses of the Host Apr. 8 Apr. 10 Ch. 14 Principles of Disease and Epidemiology Ch. 27 Environmental Microbiology Additional Lecture Day Online #2 (20 pts.) Apr. 1 Exam 2** Bring Scantron Ch. 17 Adaptive Immunity: Specific Defenses of the Host #8 (5 pts.)* Apr. 15 Apr. 17 Apr. 22 Apr. 24 Apr. 29 May 1 May 6 #9 (5 pts.)* #10 (5 pts.)* #11 (5 pts.)* #12 (5 pts.)* p. 456-459 formed elements/lymphatic Fig 16.7 p. 487-488 Ag-Ab binding, Fig 17.7, 17.8, 17.16 & 17.19, IL-12 p. 499 Clinical Case: Missing in Action Starts on p. 452 p. 401-406, epid 419-420 (up to descriptive), 422 CDC, 423 clinical focus Clinical Case: Bathroom Break Starts on p. 402 p. 784-787 Water Quality, Applications Clinical Case: Clean Water Starts on p. 773 Online #3 (20 pts.) May 8 Exam 3**: DURING SCHEDULED FINAL EXAMINATION TIME Thursday, May15th from 8:00-10:00 AM at GATE CITY BANK AUDITORIUM Bring Scantron * Blackboard post-lecture quizzes will be available on scheduled Thursdays and available until lecture meets the following Tuesday (5 days only). Announcements will be generated on Blackboard as reminders. You have 2 attempts to complete this quizzes so if your computer or internet crashes, no quiz reset will be provided. Wireless connections during quizzes are not always reliable…..using a landline may be better (campus computer clusters). 6