Comparing mitosis and meiosis This simplified diagram shows diploid cells with a chromosome complement of four. Two chromosomes from the father and two from the mother. 5 stages of division I I Mitosis Meiosis Division of diploid somatic (body) cells to create identical daughter cells, for growth and repair. Division of diploid ‘gamete mother’ cells to create haploid gametes. Genetic variation is introduced. Interphase DNA Replicated, chromosomes are indistinct Diploid (2n) Parent Cell P Play Diploid (2n) gamete mother cell Prophase (I) DNA condenses and is visible as paired chromatids. Chromosomes link up with their homologous partner. M Monopoly Metaphase (I) Chromosomes align along the middle of the cell. Nuclear membrane has disappeared and spindle apparatus forms. © www.teachitscience.co.uk 2016 Chromosomes line up in their homologous pairs. Genetic variation is introduced here due to independent assortment and crossing over (not shown in diagram). 25532 Page 1 of 3 Comparing mitosis and meiosis 5 stages of division A After Mitosis Meiosis Division of diploid somatic (body) cells to create identical daughter cells, for growth and repair. Division of diploid ‘gamete mother’ cells to create haploid gametes. Genetic variation is introduced. Chromatids are separated Homologous chromosomes are separated 2 diploid daughter cells each with 4 chromosomes. 2 haploid daughter cells each with 2 chromosomes, but containing a duplicate copy of each (chromatids not separated). Anaphase (I) The spindle pulls the chromosomes, separating the DNA to opposite poles of the cell . T Tea Telophase (I) New nuclear membranes form and cell divides to create daughter cells Prophase II, Metaphase II, Anaphase II, Telophase II The 2 haploid daughter cells divide further, a process called Meiosis II. The chromatids are separated creating 4 haploid gametes. Independent Assortment of pairs creates 4 possible gametes here Nuclei of the 4 possible gametes © www.teachitscience.co.uk 2016 25532 Page 2 of 3 Comparing mitosis and meiosis Teaching notes There are a variety of ways that the resource could be used. An information sheet used as a source for students to: answer questions e.g. What are the similarities between mitosis and meiosis? What are the differences? make models of the process of cell division using play dough identify the stages of cell division shown by photos from microscope slides. The table could be cut up for students to reassemble as a table or as a cell cycle. Remove the text from the pictures and ask students to describe what they see. © www.teachitscience.co.uk 2016 25532 Page 3 of 3