Alumni Directory Child Health Research Award Recipients and Hood Postdoctoral Research Fellows 1942 – 2014 The history of the Charles H. Hood Foundation reveals a century‐long tradition of commitment to community and child health. Countless researchers funded by the Child Health Research Awards Program have made seminal contributions that have benefited large numbers of children. Many of these scientists have also achieved brilliant careers as leaders in their fields. In its early years, the Program focused on infectious diseases, prevention, and training for health professionals. From the mid‐1940s until 1971, the Foundation supported a diversity of programs seeking to improve child health including medical research, demonstration projects, public health programs, scholarships and fellowships. As the Foundation reorganized in 1971, it increased its budget and explicitly emphasized basic science and medical research as its priorities. Over the years, expertise has been added to its Scientific Review Committee to reflect growth of research in genetics, oncology, epidemiology, and other disciplines. The Child Health Program also shifted to an exclusive focus on young investigators. Today, the Child Health Research Awards Program makes two‐year grants which support hypothesis‐driven clinical, basic science, public health, health services research, and epidemiology projects relevant to pediatrics. In addition, the Hood Foundation supports two basic science and/or clinical postdoctoral fellows in Massachusetts. The Foundation’s trustees have also made large grants in health policy and translational research to established New England investigators. To‐date, the Foundation has distributed over $63 million to New England research institutions. The following pages list all Child Health Award Recipients in alphabetical order with the date of their award, title of the original research project and current contact information. The last four pages (48 – 51) denote the 43 Hood Fellows, funded between 1989 and 2014. The Hood Foundation is immensely proud of its Award Recipients and values updates on their current endeavors. Child Health Research Award Recipients Usha Acharya, Ph.D. (2005 Award Recipient) Pathogenics and Suppression of Leber Congenital Amaurosis and Retinitis Pigmentosa 12 Related Retinal Degeneration University of Massachusetts Medical School usha.acharya@umassmed.edu David W.K. Acheson, M.D. (1995 Award Recipient) Shiga‐Like Toxin Transport Across Gastrointestinal Epithelial Cells Leavitt Partners, LLC david@leavittpartners.com Kate G. Ackerman, M.D. (2007 Award Recipient) Mechanism of Barx1 Mediated Congenital Diaphragmatic Hernia University of Rochester Medical Center kate_ackerman@urmc.rochester.edu Suneet Agarwal, M.D., Ph.D. (2013 Award Recipient) Manipulating Heteroplasmy in Mitochondrial Genetic Diseases Boston Children's Hospital suneet.agarwal@childrens.harvard.edu Caroline Alexander, Ph.D. (1999 Award Recipient) Analysis of Oncogenic Properties of Syndecan‐1 University of Wisconsin‐Madison, School of Medicine and Public Health alexander@oncology.wisc.edu Donald M. Allen, M.D. (1966 Award Recipient) Support of Research to Investigate the Possible Interrelationship of Iron and Folic Acid in Anemic Mice and the Clinical Application of this Data to the Problem of Iron Overloading as it May Apply to Children with Anemia Floating Hospital for Children at Tufts Medical Center Arnold J. Altman, M.D. (1974 Award Recipient) Relationship of Monocyte‐derived Colony Stimulating Factor (CSF) to the Granulocytosis of Juvenile Chronic Granulocytic Leukemia (CGL) University of Connecticut Health Center aaltman@ccmckids.org Donna Ambrosino, M.D. (1983 Award Recipient) Therapeutic Use of Human Hyperimmune Globulin in Haemophilus Influenzae Type B Meningitis in Infant Rats donna.ambrosino1@gmail.com Chris T. Amemiya, Ph.D. (1996 Award Recipient) Cloning of the Gene Defect for X‐Linked Lymphoproliferative Disease Benaroya Research Institute camemiya@benaroyaresearch.org Jean A. Amos, Ph.D. (1986 Award Recipient) Genetic Predisposition to Down Syndrome Specialty Labs jamos@specialtylabs.com 1
William Stanley Anderson, Ph.D., M.D. (2010 Award Recipient) The Impact of Interictal Spike Events on Visual Object Recognition Johns Hopkins University School of Medicine wanderso68@gmail.com Warren A. Andiman, M.D. (1982 Award Recipient) Rapid Diagnosis of Cytomegalovirus Infection Using Nucleic Acid Spot Hybridization Yale School of Medicine warren.andiman@yale.edu Warren A. Andiman, M.D. (1983 Award Recipient) Rapid Diagnosis of Cytomegalovirus Infection Using Nucleic Acid Spot Hybridization Yale School of Medicine warren.andiman@yale.edu Priscilla M. Andrews, (1966 Award Recipient) Support of a Demonstration and Training Program toward Developing Improved Patterns of Nurse Staffing in a Pediatric Hospital, Improving the Quality of Child Care, and Identifying the Role of a Pediatric Nurse Clinical Specialist Boston College Nancy C. Andrews, M.D., Ph.D. (1993 Award Recipient) Intestinal Iron Transport Duke University School of Medicine Nancy.Andrews@duke.edu Gabor J. Anthony, M.D. (1968 Award Recipient) Measuring Maternal Hormones on the Growth and Development of Body Organs and their Relationship to the Growth and Development of the Fetus University of Vermont College of Medicine Michael Apkon, M.D., M.B.A., Ph.D. (1997 Award Recipient) Mechanism of Cerebral Vasoregulation by Extracellular pH Yale School of Medicine michael.apkon@yale.edu June R. Aprille, Ph.D. (1973 Award Recipient) Lipid Diet and Development of Energy Metabolism as Applied to the Practical Energy Needs of the Newborn (1977 Award Recipient) Pathogenesis of Reyes Syndrome (1988 Award Recipient) Northeast Center for Analysis of Mitochondrial Diseases in Infants and Children (1990 Award Recipient) Northeast Center for Analysis of Mitochondrial Diseases in Infants and Children Washington and Lee University japrille@wlu.edu Robert J. Arceci, M.D., Ph.D. (1986 Award Recipient) Detection of Multidrug Resistance Gene Expression in Pediatric Malignancies Johns Hopkins University arcecro@jhmi.edu 2
Scott A. Armstrong, M.D., Ph.D. (2003 Award Recipient) Cooperation of MLL and FLT3 in Infant Leukemia Memorial Sloan‐Kettering Cancer Center armstros@mskcc.org Cameron Ashbaugh, M.D. (1995 Award Recipient) Virulence Genes in Group A Streptococcus Brigham and Women's Hospital cdashbaugh@partners.org Timothy W. Baba, M.D., Ph.D. (1995 Award Recipient) Prevention of Perinatal HIV‐1 Transmission by Combination Drug Therapy Tufts Medical Center tbaba@tuftsmedicalcenter.org Kamran Badizadegan, M.D. (2001 Award Recipient) Role of Structural‐Functional Heterogeneity in Membrane Microdomains in Pathogenesis of Secretory Diarrhea Boston Children's Hospital kamran.badizadegan@childrens.harvard.edu Susan Baker, M.D., Ph.D. (1984 and 1985 Award Recipient) Studies on the Role of Short‐Term Starvation on Intestinal Microvillus Barrier Function in Immature Animals Children's Hospital of Buffalo sbaker@upa.chob.edu Mark Ballow, M.D. (1975 Award Recipient) Study of the Effects of Transfer Factor on the Histocompatibility System University of Connecticut Health Center mballow@upa.chob.edu Robert S. Baltimore, M.D. (1977 and 1978 Award Recipient) Opsonic Immunity to Group B Streptococcus Yale School of Medicine robert.baltimore@yale.edu Zheng‐Zheng Bao, Ph.D. (2002 Award Recipient) Regulation of Irx4 Gene Expression in Heart Development University of Massachusetts Medical School Mercedes Becerra, Sc.D. (2004 Award Recipient) Impact of Isoniazid Prophylaxis to Prevent TB in Children Harvard Medical School mbecerra@post.harvard.edu Eugene Becker, M.D. (1948 Award Recipient) Research in Nutritional Significance of Benzoic Acid Geisel Medical School at Dartmouth Alan H. Beggs, Ph.D. (1994 Award Recipient) Autologous Myoblast Transfer for Somatic Cell Gene Therapy of Globoid Cell Leukodystrophy Boston Children's Hospital beggs@enders.tch.harvard.edu David R Beier, M.D., Ph.D. (1992 Award Recipient) Identification of tumor suppressor genes using a transgenic mouse model Brigham and Women's Hospital beier@receptor.med.harvard.edu 3
Barbara Bembery (1954 Award Recipient) Diabetes Control United Way of Massachusetts Bay b.bembrey@supportunitedway.org Charles B. Berde, M.D., Ph.D. (1986 Award Recipient) The Efficacy of Methdone for the Relief of Postoperative Pain in 3 to 7‐year‐old Children Boston Children's Hospital charles.berde@childrens.harvard.edu Jeffrey M. Bergelson, M.D. (1994 Award Recipient) Structural Basis of Echovirus‐Receptor Interactions Children's Hospital of Philadelphia bergelson@email.chop.edu Shelly C. Bernstein, M.D., Ph.D. (1987 Award Recipient) Identification of Genes Conferring Metastatic Capability in Childhood Cancer Dana‐Farber Cancer Institute shelly_bernstein@dfci.harvard.edu Charles I. Berul, M.D. (1997 Award Recipient) Electrophysiologic Properties of Transgenic Familial Hypertrophic Cardiomyopathy Mice Children's National Medical Center cberul@childrensnational.org Laura M. Bevilacqua, M.D. (1999 Award Recipient) Optical Mapping for the Characterization of Cellular Mechanisms of Inherited Ventricular Arrhythmias Boston Children's Hospital laura.bevilacqua@cardio.chboston.org Irina Bezsonova, M.Sc., Ph.D. (2012 Award Recipient) The Role of Usp7 in Pediatric Neuroblastoma. University of Connecticut Health Center bezsonova@uchc.edu Sumita Bhaduri‐McIntosh, M.D., Ph.D. (2008 Award Recipient) The Role of Regulatory T Cells in Immune Evasion During Establishment and Maintenance of Latency by EBV SUNY Stony Brook University sumita.bhaduri‐mcintosh@stonybrook.edu Diana W. Bianchi, M.D. (1990 Award Recipient) Fetal Neucleated Erythrocytes (NRBC) in Maternal Blood: a Source of Fetal Cells for Prenatal Diagnosis Tufts Medical Center dbianchi@tuftsmedicalcenter.org Suzy D.C. Bianco, Ph.D. (2008 Award Recipient) Altered GPR54 Signaling as the Genetic Basis of Pubertal Disorders University of Miami Miller School of Medicine SBianco@med.miami.edu Amelia Blackwell, Ph.D. (1957 Award Recipient) Diane R. Blake, M.D. (2001 Award Recipient) Non‐Invasive Chlamydia Screening for Adolescents: Cost‐Effective Analysis University of Massachusetts Medical School diane.blake@umassmed.edu 4
Hans H. Bode, M.D. (1970 Award Recipient) Innovative Therapeutic Approaches to a Variety of Hormonal Deficiency and Resistance States in Children Massachusetts General Hospital Clifford W. Bogue, M.D. (1994 Award Recipient) Expression and Regulation of Homeobox Genes in the Developing Lung Yale School of Medicine clifford.bogue@yale.edu Charlotte M. Boney, M.D. (1998 Award Recipient) Modulation of Mitogenic Signal Transduction during Preadipocyte Differentiation Rhode Island Hospital charlotte_boney@brown.edu Elisa Boscolo, Ph.D. (2012 Award Recipient) NOTCH Signaling during Pathological Blood Vessel Formation and Maturation Boston Children's Hospital elisa.boscolo@childrens.harvard.edu Libbie B. Bower, Ph.D. (1964 Award Recipient) In support of a program of career recruitment seeking to motivate and create an early interest in the mental health professions among selected junior and senior high school students Massachusetts Association for Mental Health Joshua A. Boyce, M.D. (1995 Award Recipient) The Role of Hypodense Mononuclear Eosinophils in Pediatric Asthma Brigham and Women's Hospital jboyce@rics.bwh.harvard.edu Renee Boynton‐Jarrett, M.D., Ph.D. (2011 Award Recipient) A Nested Case‐Control Study of Genetic and Psychosocial Determinants of Early Puberty Boston University School of Medicine renee.boyntonjarrett@bmc.org Abraham L. Brass, M.D., Ph.D. (2010 Award Recipient) Understanding Intrinsic Immunity: Investigation of IFITM3's Inhibition of Influenza A Virus Infection University of Massachusetts Medical School Abraham.Brass@umassmed.edu Roger E. Breitbart, M.D. (1993 Award Recipient) MEF2 Regulation of Early Vertebrate Cardiac Development Boston Children's Hospital breitbart@cardio.chboston.org Andrew S. Brem, M.D. (1985 Award Recipient) Hydroosmotic Response to Vasopressin: Relation to Cell pH and Volume Rhode Island Hospital andrew_brem@brown.edu Jan Breslow, M.D. (1977 Award Recipient) Cystic Fibrosis: Use of Lymphocyte Cultures for Diagnostic Testing Boston Children's Hospital breslow@mail.rockefeller.edu 5
David M. Briscoe, M.D. (1993 Award Recipient) Lymphocyte‐Endothelial Cell Interactions in Allograft Rejection: In Vitro and In Vivo Studies Boston Children's Hospital david.briscoe@childrens.harvard.edu Timothy Browder, M.D. (1993 Award Recipient) Angiogenesis Switching in Transgenic Retinoblastoma Boston Children's Hospital Rosalind S. Brown, M.D., C.M., FRCPC (1979 Award Recipient) Thyroid Stimulating Immunoglobins (TSI) in Childhood Graves' Disease (1979) Boston Children's Hospital rosalind.brown@childrens.harvard.edu Elizabeth Brown, M.D. (1982 Award Recipient) The Effects of Early Behavioral and Environmental Modification on Infants with Severe Respiratory Distress Boston Medical Center Rosalind S. Brown, M.D., C.M., FRCPC (1982 Award Recipient) Idiotype‐Antiidiotype Reactions in Childhood Graves' Disease Boston Children's Hospital rosalind.brown@childrens.harvard.edu Robert H. Brown, M.D., D.Phil. (1984 Award Recipient) Investigations of the Pathogensis of Human Motorneuron Disorders Using Poliovirus University of Massachusetts Medical School robert.brown@umassmed.edu Martina Brueckner, M.D. (1997 Award Recipient) Cloning the Mouse iv (inversus viscerum) Gene Yale School of Medicine martina.brueckner@yale.edu Gail A. Bruns, M.D., Ph.D. (1972 Award Recipient) A Diagnostic Method for Lysosomal Deficiency Disease Boston Children's Hospital bruns@enders.tch.harvard.edu Virginia M. Burns (1956 Award Recipient) Jane C. Burns, M.D. (1986 and 1987 Award Recipient) Polymerase Activity in Lymphocyte Culture Supernatants from Patients with Kawasaki Disease: Search for the Etiologic Agent University of California San Diego School of Medicine jcburns@ucsd.edu Heather H. Burris, M.D., M.P.H. (2013 Award Recipient) The Epigenetics of the Cervix, Linking the Environment to Spontaneous Preterm Delivery Beth Israel Deaconess Medical Center heburris@bidmc.harvard.edu Joan R. Butterton, M.D. (1998 Award Recipient) Mucosal Immunity to Cholera‐Vectored EHEC Antigens Massachusetts General Hospital jbutterton@partners.org 6
Ernesto Canalis, M.D. (1978 and 1979 Award Recipient) Effect of Serum Factors on Bone Formation St. Francis Hospital and Medical Center ecanalis@stfranciscare.org Michael Cappello, M.D. (1996 Award Recipient) The Hookworm Anticoagulant: A Novel Inhibitor of Tumor Metastasis Yale School of Medicine michael.cappello@yale.edu Dennis E. Carey, M.D. (1991 Award Recipient) Regulation of Growth Place Chondrocyte Maturation and Calcification by Thyroid Hormone Schneider Children's Hospital of Long Island carey@lij.edu Kathleen S. Carlson, M.D. (1986 Award Recipient) Mechanisms of Delayed Lung Maturity in Fetuses of Diabetic Mothers Flower Hospital kathy.carlson@promedica.org Thomas O. Carpenter, M.D. (1987 Award Recipient) Use of 24,25(0H)2D3 as Adjunctive Therapy for Familial Hypophosphatemic Rickets (FHR) Yale School of Medicine thomas.carpenter@yale.edu Christopher R. Carpenter, M.D., Ph.D. (1994 Award Recipient) PtdIns‐4‐Phosphate 5‐Kinase in p21rac Signaling, Washington University School of Medicine in St. Louis carpenterc@wustl.edu William J. Cashore, M.D. (1977 Award Recipient) Displacement of Bilirubin from Albumin by Drugs Women & Infants Hospital of Rhode Island wcashore@wihri.org Emanuela Castigli, Ph.D. (1994 Award Recipient) The B Cell CD40 Antigen: Functional Study by Gene Targeting and Introduction of Transgenes Boston Children's Hospital emanuela.castigli@childrens.harvard.edu K. Lynn Cates, M.D. (1980 Award Recipient) Host Response to Haemophilus Influenzae University of Connecticut Health Center Elizabeth A. Catlin, M.D. (1989 Award Recipient) Sex‐specific Fetal Lung Development and Mullerian Inhibiting Substance Massachusetts General Hospital ecatlin@partners.org Valeria Cavazzuti, Ph.D. (1982 Award Recipient) Oculo‐motor Rapid Continuous Performance Tasks (OM‐RCPT): a Proposal for Clinical Assessment of Neurophysiopsychological Dysfunctions in Young Infants with IVH Boston Children's Hospital Yee‐Ming Chan, M.D., Ph.D. (2013 Award Recipient) Kisspeptin as a Novel Tool for the Evaluation of Delayed Puberty Boston Children's Hospital yee‐ming.chan@childrens.harvard.edu 7
Tien‐Lan Chang, M.D. (1989 Award Recipient) The Role of Maternal IgG Antibody in the Ontogeny of Immune Response to Dietary Antigens Massachusetts General Hospital tchang5504@aol.com Nancy Charest, M.D. (1990 Award Recipient) Regulation of Gene Expression in Developing Epididymis Children's Hospital at Dartmouth Talal A. Chatila, M.D. (1989 Award Recipient) Molecular Basis of Childhood T Cell Immunodeficiencies Washington University School of Medicine in St. Louis chatila@peds.wustl.edu Sarah H. Cheeseman, M.D. (1982 Award Recipient) Cytomegalovirus Acquisition in Nursery and Pediatric Nurses ‐‐ An Occupational Hazard? University of Massachusetts Medical School sarah.cheeseman@umassmed.edu Dong Feng F Chen, M.D., Ph.D. (1999 Award Recipient) Regulation of Neural Differentiation by Ccl‐2 Schepens Eye Research Institute dongfeng_chen@meei.harvard.edu Chinfei Chen, M.D., Ph.D. (2001 Award Recipient) The Effects of Aberrant Neuronal Activity and Seizures on Synapse Maturation in the Mammalian Thalamus Boston Children's Hospital chinfei.chen@childrens.harvard.edu Jing Chen, Ph.D. (2011 Award Recipient) Targeting Wnt Pathway for Retinopathy of Prematurity Boston Children's Hospital jing.chen@childrens.harvard.edu Andrew J. Chess, M.D. (1997 Award Recipient) Allelic Inactivation of Developmental Regulatory Genes Mount Sinai School of Medicine andrew.chess@mssm.edu Hongbo Chi, Ph.D. (2004 Award Recipient) Regulation of Neural Tube Development by MEKK4 St. Jude Children's Research Hospital hongbo.chi@stjude.org Helen Christou, M.D. (2002 Award Recipient) Molecular Mechanisms Underlying Vascular Responses to Extracellular Acidosis Boston Children's Hospital helen.christou@childrens.harvard.edu Andrea L. Ciaranello, M.D., M.P.H. (2014 Award Recipient) Novel Approaches to Improve Medication Adherence among HIV‐infected Adolescents: the CEPAC‐Adolescent Model Massachusetts General Hospital aciaranello@partners.org Michael J. Cieslewicz, Ph.D. (2002 Award Recipient) Transcriptional Regulation of Capsule Biosynthesis in Group B Streptococcus Boston Children's Hospital michael.cieslewicz@childrens.harvard.edu 8
Christos Cladaras, Ph.D. (1988 Award Recipient) Genetic Variation in the Receptor Binding Domain of ApoB‐100 and Atherosclerosis Boston Medical Center Laurie E. Cohen, M.D. (1996 Award Recipient) Molecular Mechanisms of Pit‐1 Gene Mutations in Combined Pituitary Hormone Deficiency Boston Children's Hospital laurie.cohen@childrens.harvard.edu Steven D. Colan, M.D. (1984 Award Recipient) Arterial Input Impedence by a Noninvasive Technique Boston Children's Hospital colan@alum.mit.edu F. Sessions Cole, M.D. (1981 Award Recipient) Genetic and Developmental Regulation of Complement Biosynthesis in Monocytes and Macrophages St. Louis Children's Hospital cole@kids.wustl.edu Jonathan Seth Comer, Ph.D. (2012 Award Recipient) A Controlled Trial of Telemethods to Expand the Availability of Parent‐Child Interaction Therapy for Disruptive Preschoolers Boston University jcomer@bu.edu John P. Connelly, M.D. (1971 Award Recipient) Pediatric Nurse Practitioner Program Massachusetts General Hospital John C. Coolidge, M.D. (1963 Award Recipient) Follow‐up Study to a 1953 Study of Children who Evidenced School Phobia Judge Baker Children's Center Cathleen L. Cooper, Ph.D. (1998 Award Recipient) Transcriptional Control of Cell Cycle Progression and Normal Blood Development The Center for Scientific Review at the National Institutes of Health cooperc@csr.nih.gov Douglas B. Cowan, Ph.D. (2000 Award Recipient) Endotoxin‐Induced Cardiac Signal Transduction Boston Children's Hospital douglas.cowan@childrens.harvard.edu Aidan K. Curran, B.Sc., Ph.D. (2001 Award Recipient) Ventral Medullary Inhibition and Control of Upper Airway (UA) Patency Following Acute Increases in Blood Pressure; Implications for Sudden Infant Death Syndrome (SIDS) Geisel Medical School at Dartmouth aidan.k.curran@dartmouth.edu Florence Cyr, M.S. (1957 Award Recipient) William Dameshek, M.D. (1949 Award Recipient) Research in Hematology Tufts Medical Center Christiane E. I. Dammann, M.D. (2001 Award Recipient) The Role of Neuregulin in Fetal Surfactant Synthesis Tufts Medical Center dammann.christiane@mh‐hannover.de
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Alan D. D'Andrea, M.D. (1989 Award Recipient) Function of the Erythropoietin Receptor in Normal Erythropoiesis and in Pediatric Disease States Dana‐Farber Cancer Institute Alan_Dandrea@dfci.harvard.edu Alan J. Davidson, M.D., Ph.D. (2005 Award Recipient) Role of the cdx Genes and their Downstream Targets in Hematopoietic Stem Cell Formation Massachusetts General Hospital ajdavidson@partners.org Michael A. Davis, Sc.D. (1972 Award Recipient) Evaluation of Bone‐Scanning Agent (Technetium‐99m Polyphosphate) Boston Children's Hospital synergyltd@aol.com David J. DeFranco, D.M.D., D.M.Sc. (1991 Award Recipient) Influences of Mechanical Forces on Gene Expression During Craniofacial Development Milan Dentists & Orthodontists ddefranco@tin.it Penelope H. Dennehy, M.D. (1985 Award Recipient) Nosocomial Rotavirus Infection ‐‐ Possible Routes of Transmission Rhode Island Hospital penelope_dennehy@brown.edu Lee A. Denson, M.D. (2000 Award Recipient) Cytokine Regulation of Growth Hormone Signaling Cincinnati Children's Hospital Medical Center lee.denson@cchmc.org
Paul DePaola (1966 Award Recipient) Support of a Reevaluation of the Dental Health of Children who had Participated in the Study of Prophylaxis Incorporated in the Dental Screening of the 1965 "Head Start Program" in Cambridge Cambridge Community Services Ruben Diaz, M.D., Ph.D. (1997 Award Recipient) Calcium Sensing Receptor Regulation of Parathyroid Hormone Boston Children's Hospital Lindsay J. DiStefano, Ph.D. (2013 Award Recipient) Pediatric Lower Extremity Injury Prevention: Monitoring Changes Over Time University of Connecticut lindsay.distefano@uconn.edu Patricia K. Donahoe, M.D. (1973 Award Recipient) Study of Factors, Which Control Regression of Fetal Organs that May Have Clinical Application to the Control of Childhood Tumor Growth Massachusetts General Hospital pdonahoe@partners.org Robert M. Donaldson, M.D. (1970 Award Recipient) Development of Intestinal Function, Particularly Protein Absorption, in the Fetus and Newborn Boston Medical Center Lesley Doughty, M.D. (2001 Award Recipient) Viral Modulation of the Immune Response Cincinnati Children's Hospital Medical Center lesley.doughty@cchmc.org
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Simon L. Dove, Ph.D. (2002 Award Recipient) Proteins from the Bacterial Pathogen Pseudomonas Aeroginosa that Interact with its Transcription Machinery Boston Children's Hospital simon.dove@childrens.harvard.edu Evan B. Dreyer, M.D., Ph.D. (1989 Award Recipient) A Thy‐1 Receptor and CNS Neurite Outgrowth Glaucoma Cataract Consultants evandreyer@yahoo.com Raymond S. Duff, M.D. (1968 Award Recipient) To Study the Interrelationships Between Patient Care and Professional Learning in a Large, Urban Pediatric Clinic Yale School of Medicine Frank H. Duffy, M.D. (1973 Award Recipient) Pilot Study of the Use of the Visual Evoked Response in the Diagnosis of Ambylopia Ex Anopsia at an Earlier Age (Infancy) Than is Now Possible Using Standard Techniques (1973) ‐ Study of Biculline Response in Experimental Amblyopia (1976) Boston Children's Hospital frank.duffy@childrens.harvard.edu Anna Dunaevsky, Ph.D. (2002 Award Recipient) Synapse Formation and Maintenance in Normal and GluRd2 Deficient Mice University of Nebraska Medical Center adunaevsky@unmc.edu Jeffrey Daniel Dvorin, M.D., Ph.D. (2011 Award Recipient) Functional Characterization of an Essential Protein Kinase in the Malaria Parasite Plasmodium Falciparum Boston Children's Hospital Jeffrey.Dvorin@childrens.harvard.edu Paul J. Edelson, M.D. (1979 Award Recipient) A Tissue Culture Model of Chronic Granulomatous Disease Boston Children's Hospital pe30@columbia.edu Roger A. Edwards, Sc.D. (2012 Award Recipient) Use of a Computer Agent to Promote and Support Breastfeeding Northeastern University ro.edwards@neu.edu R.H. Egdahl, M.D. (1964 Award Recipient) Assist Two New Members in the Department of Surgery to Initiate and Establish Research in Cardiovascular Fetal Physiology and Endocrinology Boston University School of Medicine Richard A. Ehrenkranz, M.D. (1979 Award Recipient) Detection of In‐Vivo Lipid Peroxidation During Oxygen Administration to Neonates (1979) ‐ Composition and Nutritional Quality of Preterm Human Milk (1980) Yale School of Medicine richard.ehrenkranz@yale.edu 11
Richard A. Ehrenkranz, M.D. (1980 Award Recipient) Composition and Nutritional Quality of Preterm Human Milk Yale School of Medicine richard.ehrenkranz@yale.edu Stephanie C Eisenbarth, M.D., Ph.D. (2013 Award Recipient) Targeting Dendritic Cells to Block Allergen Sensitization in Asthma Yale School of Medicine stephanie.eisenbarth@yale.edu R. Cannon Eley, M.D. (1967 Award Recipient) Partial Support of the Establishment of a Cystic Fibrosis Clinic Roger Williams Medical Center Martha M. Eliot, M.D. (1959 Award Recipient) Grants Towards Furthering the Overall Purposes and Programs of the Massachusetts Committee on Children and Youth (1959‐1967) Massachusetts Committee on Children and Youth Felix Engel, Ph.D. (2006 Award Recipient) Promotion of Mammalian Cardiac Regeneration through Cardiomyocyte Proliferation Boston Children's Hospital felix.engel@childrens.harvard.edu Elizabeth C. Engle, M.D. (1997 Award Recipient) Cloning the Gene for Congenital Fibrosis of the Extraocular Muscles Boston Children's Hospital elizabeth.engle@childrens.harvard.edu
Michael F. Epstein, M.D. (1978 Award Recipient) Beta‐sympatho‐mimetic Agonists and Fetal Lung Surfactant Metabolism Beth Israel Deaconess Medical Center mepstein@bidmc.harvard.edu Richard W. Erbe, M.D. (1976 Award Recipient) Disordered Amino Acid Metabolism in Oculocerebral Renal Syndrome of Lowe Women & Children's Hospital of Buffalo folate@aol.com Alan B. Ezekowitz, MBChB, DPhil, FAAP (1985 Award Recipient) Molecular Cloning of an Interferon Responsive Macrophage Specific Receptor Cardinal Partners Alan.Ezekowitz@EmpiraMed.com John T. Fahey, M.D. (1987 Award Recipient) Mechanism of Lactic Acidemia During Low Cardiac Output in Lambs: Changes with Postnatal Age Yale School of Medicine john.fahey@yale.edu Douglas V. Faller, M.D., Ph.D. (1983 Award Recipient) The Use of Cloned Tumor‐Virus Gene Products and H‐2 Gene Products to Study the Recognition and Rejection of Tumor Cells by Killer T Lymphocytes Boston University School of Medicine dfaller@bu.edu Susan E. Fasoli, Sc.D., OTR (2005 Award Recipient) Upper Limb Rehabilitation Robotics for Children with Cerebral Palsy Spaulding Rehabilitation Hospital sfasoli@partners.org
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David Faust, Ph.D. (1984 Award Recipient) The Neuropsychological Functioning of Children with Moderately Raised Lead Levels University of Rhode Island faust@uri.edu Margaret E. Feeney, M.D. (2004 Award Recipient) Pediatric HIV‐specific Immune Responses and AIDS‐free Survival University of California‐ San Francisco‐ School of Medicine feeneym@medsfgh.ucsf.edu Francis X. Fellers, M.D. (1967 Award Recipient) Research Fellowship on "A New Method of Dietary Management for Children Afflicted with Cystinosis" (1967) ‐ Research Concerning Adequate‐Diet Bone Disease Syndrome in Children (1969) Boston Children's Hospital John D. Fernstrom, Ph.D. (1973 Award Recipient) Milk Constituents and Brain Serotonin Synthesis Massachusetts Institute of Technology fernstromjd@msx.upmc.edu James L.M. Ferrara, M.D. (1987 Award Recipient) In Vivo Use of Anti‐LFA‐1 to Enhance Engraftment and Prevent Graft‐Versus‐Host Disease After Bone Marrow Transplantation University of Michigan ferrara@umich.edu Lindo Ferrini, M.S.W. (1955 Award Recipient) Cottage Parents at Residential Treatment Centers for Children
Stefan Feske, M.D. (2006 Award Recipient) Identification of a Genetic Defect Causing Immunodeficiency, Myopathy and Ectodermal Dysplasia New York University School of Medicine Stefan.Feske@med.nyu.edu John M. Fiascone, M.D. (1987 Award Recipient) The Effect of Terbutaline Administration on Lung Function in the Fetal Rabbit Model of Respiratory Distress Syndrome Tufts Medical Center jfiascone@tuftsmedicalcenter.org Barry A. Finette, M.D., Ph.D. (1993 Award Recipient) Molecular Effects of Passive and Active Maternal Cigarette Smoking in Normal Human Newborns University of Vermont College of Medicine barry.finette@uvm.edu Judith C. Fleming, Ph.D. (2002 Award Recipient) Functional Analysis of the Thiamine Transporter, SLC19A3 Boston Children's Hospital judith.fleming@childrens.harvard.edu Johnathan A. Fletcher, M.D. (1990 Award Recipient) Cytogenetic Analysis of Bone and Soft Tissue Tumors of Childhood Brigham and Women's Hospital jfletcher@partners.org Mark A. Fletcher, M.D. (1993 Award Recipient) Development of Novel Antibodies Against Gram‐Negative Bacteria Wyeth Pharmaceuticals France 13
Eric S Folker, Ph.D. (2014 Award Recipient) The Role of Nuclear Positioning in Centronuclear Myopathies Boston College eric.folker@bc.edu Pamela Follett, M.D. (2003 Award Recipient) The Role of Repetitive Hypoxia in Premature White Matter Injury Lewis Rhodes Labs pamela.follet@earthlink.net Yick W. Fong, Ph.D. (2014 Award Recipient) The Role of the Dyskerin Complex in Stem Cell‐specific Transcriptional Control and the Pathogenesis of Dyskeratosis Congenita Brigham and Women's Hospital YFong@partners.org Sarah Fortune, M.D. (2007 Award Recipient) At the Host‐Pathogen Interface: Characterization of a Candidate Mycobacterial Toxin Harvard School of Public Health sfortune@hsph.harvard.edu Ramsay L. Fuleihan, M.D. (1992 Award Recipient) Regulation of HIV‐1 Gene Expression by Ia Molecules Northwestern University r‐fuleihan@northwestern.edu Nadine Gaab, Ph.D. (2008 Award Recipient) Neural Pre‐Markers of Developmental Dyslexia in Children prior to Reading Onset Boston Children's Hospital nadine.gaab@childrens.harvard.edu Mae Gailani, M.D. (1997 Award Recipient) Identification of Protein Interactions with Human Patched Yale School of Medicine Alison A. Galbraith, M.D., M.P.H. (2006 Award Recipient) Children in High‐Deductible Health Plans: Health Care Use and Impact of Chronic Conditions Harvard Pilgrim Health Care alison_galbraith@hphc.org Patrick Gallagher, M.D. (1993 Award Recipient) Molecular Mechanisms of Regulation of the Human Erythrocyte Ankyrin Gene Yale School of Medicine patrick.gallagher@yale.edu George E. Gardner, M.D., Ph.D. (1957 Award Recipient) Anorexia Nervosa Boston Children's Hospital George E. Gardner, M.D., Ph.D. (1959 Award Recipient) Construction of an Emotional Development Task Test Boston Children's Hospital Arvin Garg, M.D., M.P.H. (2012 Award Recipient) Do Basic Unmet Material Needs and Social Safety Nets Influence Child Maltreatment Risk? A Nested Case‐Control Study Boston Medical Center arvin.garg@bmc.org 14
Scott C Garman, Ph.D. (2005 Award Recipient) Structural Studies on Fabry Disease University of Massachusetts Amherst garman@biochem.umass.edu Stanley Garn, B.A. (1947 Award Recipient) Karen M. Gaudio, M.D. (1984 Award Recipient) Treatment of Acute Renal Failure Yale School of Medicine Raif S. Geha, M.D. (1978 and 1979 Award Recipient) Regulation of the Human Immune Response Boston Children's Hospital raif.geha@childrens.harvard.edu Niels Geijsen, Ph.D. (2004 Award Recipient) Dissection of Molecular Pathways Mediating Epigenetic Gene Modification Hubrecht Institute n.geijsen@hubrecht.eu Sydney S. Gellis, M.D. (1954 Award Recipient) Amino Acid Metabolism in Children Rachel M. Gerstein, Ph.D. (1998 Award Recipient) Extrinsic Factors Controlling B Cell Development University of Massachusetts Medical School rachel.gerstein@umassmed.edu Joseph M. Gertner, M.B., MRCP (1978 Award Recipient) Studies on Stress‐Related Neonatal Hypocalcemia Yale School of Medicine j.gertner@rcn.com
Tal Geva, M.D. (1999 Award Recipient) Mechanism of right ventricular dysfunction due to chronic pulmonary regurgitation Boston Children's Hospital tal.geva@childrens.harvard.edu Satish Ghatpandes, Ph.D. (2006 Award Recipient) Novel Mechanisms of Embryo‐Protection: The Role of Adenosine Action in the Developing Heart Achillion Pharmaceuticals Inc. ghatpandes@gmail.com Matthew W. Gillman, M.D., S.M. (1988 Award Recipient) Tracking of Childhood Blood Pressure Harvard Pilgrim Health Care matthew_gillman@harvardpilgrim.org Matthew W. Gillman, M.D., S.M. (1990 Award Recipient) Multiple‐Visit Tracking of Blood Pressure from Childhood to Early Adulthood Harvard Pilgrim Health Care matthew_gillman@harvardpilgrim.org David N. Glass, M.D. (1977 Award Recipient) HLA Genetics of Juvenile Arthritis Brigham and Women's Hospital Verena Gobel, M.D. (1994 Award Recipient) Neurofibromatosis II (NF2) Tumor Suppressor Gene Homologs in c. elegans Massachusetts General Hospital vgobel@partners.org 15
Donald Goldmann, M.D. (1981 Award Recipient) Neonatal E. Coli K1 Colonization and Infection: the Role of Bacterial Pili Boston Children's Hospital don.goldmann@childrens.harvard.edu Allan M. Goldstein, M.D. (2003 Award Recipient) A New Model of Intestinal Aganglionosis: Essential Role for BMP4 in Enteric Nervous System Development Massachusetts General Hospital agoldstein@partners.org Allan Goodman, M.D. (1968 Award Recipient) Massachusetts Parents Association for the Deaf and Hard of Hearing Boston Children's Hospital Julie Elizabeth Goodwin, M.D. (2011 Award Recipient) The Role of the Endothelial Glucocorticoid Receptor in the Development of Atherosclerosis Yale School of Medicine julie.goodwin@yale.edu Catherine M. Gordon, M.D., M.Sc. (2001 Award Recipient) Vitamin D Screening in Adolescents Warren Alpert Medical School of Brown University cgordon1@lifespan.org Richard Iain Gregory, Ph.D. (2007 Award Recipient) The Role of MicroRNAs in DiGeorge Syndrome Boston Children's Hospital rgregory@enders.tch.harvard.edu Carol L. Griffin (1965 Award Recipient) In support of a pilot demonstration concerning the effectiveness of therapeutic tutoring as an adjunct to psychotherapy of children with refractory learning disabilities South Shore Mental Health Jeffrey R. Gruen, M.D. (1990 Award Recipient) Identifying DNA Landmarks for Primary Hemochromatosis Yale School of Medicine jeffrey.gruen@yale.edu Nicholas G. Guerina, M.D., Ph.D. (1989 Award Recipient) Development of a Pilus Vaccine Against Haemophilus Influenzae Tufts Medical Center nguerina@tuftsmedicalcenter.org David A. Guertin, Ph.D. (2010 Award Recipient) Nutrient Sensing Pathways in Muscle Regeneration University of Massachusetts Medical School david.guertin@umassmed.edu Vandana Gupta, Ph.D. (2014 Award Recipient) Elucidation of Molecular Pathways and Therapeutic Developments in Nemaline Myopathy Boston Children's Hospital vgupta@enders.tch.harvard.edu Emanuela Gussoni, Ph.D. (2000 Award Recipient) Isolation and Characterization of Stem Cells from Human Skeletal Muscle Boston Children's Hospital gussoni@enders.tch.harvard.edu 16
H. I. Margolis, D.M.D. (1955 Award Recipient) In Vivo Technique for the Evaluation of Bone Mineralization Variations in Children M. Kyle Hadden, Ph.D. (2012 Award Recipient) Vitamin D3 Analogues as Hedgehog Pathway Inhibitors University of Connecticut kyle.hadden@uconn.edu James E. Haddow, M.D. (1971 Award Recipient) Divalent Metal Excretion: Enhancement by Spironolactone Boston University School of Medicine jhaddow@fbr.org Margarita Hadzopoulou‐Cladaras, Ph.D. (1991 Award Recipient) ApoB Domain Required for LDL Assembly and Secretion Aristotle University of Thessaloniki cladaras@bio.auth.gr Robert J. Haggerty, M.D. (1959 Award Recipient) Funds to employ a social worker to the staff of the Family Health Care Program in cooperation with the Boston Lying‐In Hospital and Children's Hospital Harvard Medical School Joseph J. Halett, M.D. (1980 Award Recipient) Effect of Warfarin on Chondrogenesis Memorial Hospital of Rhode Island joseph_hallett@brown.edu Silva H. Hanissian, Ph.D. (1996 Award Recipient) Structural Analysis of CD40 Signaling University of Tennessee Health Science Center Paul R. Harmatz, M.D. (1981 Award Recipient) A Study of the Transport of IgZ Immune Complexes into Breastmilk and the Binding and Transport of IgA Immune Complexes Into the Neonatal Intestine Children's Hospital and Rehabilitation Center of Oakland pharmatz@mail.cho.org Paul R. Harmatz, M.D. (1982 Award Recipient) A Study of the Transport of IgZ Immune Complexes into Breastmilk and the Binding and Transport of IgA Immune Complexes Into the Neonatal Intestine Children's Hospital and Rehabilitation Center of Oakland pharmatz@mail.cho.org Jason B Harris, M.D., M.P.H. (2009 Award Recipient) Cellular Immune Responses to Vibrio Cholerae Infection Massachusetts General Hospital jbharris@partners.org John E. Harris, M.D., Ph.D. (2011 Award Recipient) Targeting the IFN‐Gamma Signaling Pathway for the Treatment of Vitiligo University of Massachusetts Medical School John.Harris@umassmed.edu 17
Emil M. Hartl, Ph.D. (1956 Award Recipient) A Group Therapy Pilot Project (1964 Award Recipient) Objective Assessment of an Experimental Program which is Concerned with the Socialization to Work with the Problem Adolescent Charles Hayden Goodwill Inn for Boys Steven Hatch, M.D. (2011 Award Recipient) Maternally Derived Anti‐Dengue Antibodies and the Risk of DHF in Infants University of Massachusetts Medical School steven.hatch@umassmed.edu Judith Hellman, M.D. (1998 Award Recipient) In Vitro Biological Activity of Endotoxin Associated Outer Membrane Proteins University of California San Francisco hellmanj@anesthesia.ucsf.edu Sonia Hernandez‐Diaz, M.D., D.P.H. (2004 Award Recipient) Endocrine Disruptors and Male Genital Malformations Harvard School of Public Health shernan@hsph.harvard.edu John T. Herrin, MBBS, FRACP (1971 Award Recipient) Protein Excretion as an Indicator of Prognosis and Correlation with Therapy Boston Children's Hospital john.herrin@childrens.harvard.edu Victoria L. Herzberg, Ph.D. (1984 and 1985 Award Recipient) The Role of Insulin and Insulin‐Like Growth Factors in Normal and Abnormal Cell Proliferation Geisel Medical School at Dartmouth Joseph A. Hill, M.D., Ph.D. (1994 Award Recipient) Long Q‐T Syndrome and Molecular Mechanism of a Cardiac Arrhythmia University of Texas Southwestern Medical School joseph.hill@utsouthwestern.edu Raymond L. Hintz, M.D. (1972 Award Recipient) Study of the Role Played by Somatomedin in Fetal Growth and Development University of Connecticut hintz@stanford.edu Hillel I. Hochman, M.D. (1974 Award Recipient) In Support of Experimental Studies on Idiopathic Lactic Acidosis Boston City Hospital W. Andrew Hodge, M.D. (1985 Award Recipient) The Impositions of Posture on Stance Equilibrium in the Spastic Quadriplegic Child Hodge BioMotion Orthopedics wandrewhodgemd@aol.com Diane Hoffman‐Kim, Ph.D. (2004 Award Recipient) Axon Guidance by Permissive and Inhibitory Molecular Gradients Brown University diane_hoffman‐kim@brown.edu 18
Ingrid A. Holm, M.D., M.P.H. (1995 Award Recipient) Localization of the Gene Defective in X‐
Linked Hypophosphatemic Rickets Boston Children's Hospital ingrid.holm@childrens.harvard.edu Lewis B. Holmes, M.D. (1972 Award Recipient) Improving the Diagnostic Evaluation and Genetic Counseling of Congenitally Malformed Newborn Infants (1972) ‐ Role of Extracellular Matrix in Limb Malformation in Mice and Humans (1975) Massachusetts General Hospital holmes.lewis@mgh.harvard.edu Lewis B. Holmes, M.D. (1975 Award Recipient) Role of Extracellular Matrix in Limb Malformations in Mice & Humans Massachusetts General Hospital holmes.lewis@mgh.harvard.edu Gregory L. Holmes, M.D. (1984 Award Recipient) Effect of Hormones on the Development of Seizures in the Immature Brain Dartmouth‐Hitchcock Medical Center gregory.l.holmes@dartmouth.edu Alan C. Homans, M.D. (1989 Award Recipient) Hematopoiesis in Down Syndrome Fletcher Allen Health Care alan.homans@vtmednet.org Bruce H. Horwitz, M.D., Ph.D. (1999 Award Recipient) Regulation of Co‐Stimulatory activity by NF‐
kappaB Brigham and Women's Hospital bhorwitz@rics.bwh.harvard.edu Margaret K. Hostetter, M.D. (1980 Award Recipient) C3b Binding Affinities of Pneumococcal Polysaccharides: a Correlate of Virulence in Childhood Pneumococcal Bacteremia Cincinnati Children's Hospital Medical Center margaret.hostetter@cchmc.org Peter J. Hotez, M.D., Ph.D. (1992 Award Recipient) Molecular Pathogenesis of Pediatric Hookworm Infection Baylor College of Medicine hotez@bcm.edu Thomas J. Hougen, M.D. (1980 Award Recipient) Myocardial Monovalent Cation Transport in Man Georgetown University Hospital thougen@aol.com Anna T. Howard, (1960 Award Recipient) Completion of the Massachusetts Survey of Nursing Needs and Resources Massachusetts/Rhode Island League for Nursing Victor W. Hsu, M.D. (1996 Award Recipient) Mechanism of Cellular Quality Control Brigham and Women's Hospital vhsu@rics.bwh.harvard.edu Johannes Huebner, M.D. (1998 Award Recipient) Capsular Polysaccharides and Enterococcal Infections Brigham and Women's Hospital 19
Christopher Hug, M.D., Ph.D. (2004 Award Recipient) Signaling of Acrp30/Adiponectin and T‐
cadherin in Diabetes Boston Children's Hospital christopher.hug@childrens.harvard.edu James R. Hughes, M.D., M.P.H. (1968 Award Recipient) To Determine How Primary Medical Care is Being Delivered in a Rural Community Where No Systematic Program Exists for Reaching the Pre‐School Population Dartmouth‐Hitchcock Medical Center james.r.hughes@dartmouth.edu Robert Husson, M.D. (1992 Award Recipient) Maternal Immunity and Virus Variation in Vertical HIV Transmission Boston Children's Hospital robert.husson@childrens.harvard.edu Newton E. Hyslop, M.D. (1972 Award Recipient) Studies on Human Milk and Nutritional Requirements of Lactating Human Females Massachusetts General Hospital nhyslop@tulane.edu Dimitrios Iliopoulos, Ph.D. (2011 Award Recipient) Identification of Novel Molecular Circuits in Pediatric Ulcerative Colitis Dana‐Farber Cancer Institute dimitrios_iliopoulos@dfci.harvard.edu Julie R. Ingelfinger, M.D. (1977 Award Recipient) Renal Perfusion and Function in Post‐
Transplant Hypertension Boston Children's Hospital jingelfinger@partners.org Esther Jacobwitz Israel, M.D. (1987 Award Recipient) A Study of the Development of the Human Intestinal Barrier Massachusetts General Hospital eisrael1@partners.org Shirley Jankelevich, M.D. (1994 Award Recipient) Interaction of Epstein‐Barr Virus with Nuclear Matrix and Metaphase Scaffold National Institute of Allergy and Infectious Diseases Esther Jaquith (1960 Award Recipient) Support of a Single Interagency Service for the Registration of Adoptive Children and Homes Massachusetts Adoption Resource Exchange Patrick Y. Jay, M.D., Ph.D. (2002 Award Recipient) The Function of Nkx2‐5 in Cardiac Hypertrophy and Failure Washington University School of Medicine in St. Louis jay_p@kids.wustl.edu Douglas M. Jefferson, Ph.D. (1987 Award Recipient) Regulation of Liver Specific Gene Expression Tufts University School of Medicine douglas.jefferson@tufts.edu Frances E Jensen, M.D. (1992 Award Recipient) Acute and Long‐Term Anti‐convulsant Efficacy of Novel Excitatory Amino Antagonists in a Model of Hypoxia‐Induced Neonatal Seizures Boston Children's Hospital frances.jensen@childrens.harvard.edu
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Jun Jiang, M.D., Ph.D. (2014 Award Recipient) Trisomy Correction in Down's Syndrome Mouse Models University of Massachusetts Medical School jun.jiang@umassmed.edu George M. Johnson, M.D. (1990 Award Recipient) Pathogenesis of Staphylococcus Epidermis Infections: the Roles and Mechanisms of Extracellular Bacterial Products in Evasion of Opsonophagocytic Killing Medical University of South Carolina johnsogm@musc.edu Chester N. Jones, M.D. (1946 Award Recipient) Study of Nutritional Requirements in Disease Massachusetts General Hospital Paul Jubinsky, M.D., Ph.D. (1993 Award Recipient) Expression and Function of Human GM‐CSF Receptor Children's Hospital at Montefiore pjubinsk@montefiore.org Harald Jueppner, M.D. (1989 Award Recipient) Studies of Parathyroid Hormone‐Related Peptide and Its Receptors in Bone, Placenta and Breast Tissue Massachusetts General Hospital jueppner@helix.mgh.harvard.edu Jeffrey S. Kahn, M.D. (2001 Award Recipient) A Novel Approach to a Respiratory Syncytial Virus Vaccine University of Texas Southwestern Medical Center jeffrey.kahn@utsouthwestern.edu
Saul J. Karpen, M.D., Ph.D. (1998 Award Recipient) Cytokine Regulation of Bile Acid Transport Gene Baylor College of Medicine skarpen@bcm.tmc.edu Hideko Kasahara, M.D., Ph.D. (1999 Award Recipient) Protein Phosphorylation of the Cardiac Homeoprotein Csx/Nks2.5 University of Florida hkasahar@ufl.edu Ben Z. Katz, M.D. (1986 Award Recipient) Epstein‐Barr Virus (EBV) Associated Lymphoproliferations in Childhood AIDS Children's Memorial Hospital bkatz@northwestern.edu L. Lyndon Key, M.D. (1984 Award Recipient) The Effects of Gold Therapy on In Vitro Degradation of Bone by Monocytes Medical University of South Carolina keyl@musc.edu Paul S. Kim, M.D. (1995 Award Recipient) Mouse Model of Endoplasmic Reticulum Storage Diseases University of Cincinnati Donald C. Klein, Ph.D. (1954 Award Recipient) School Entry Adjustments Robert Klein, M.D. (1963 Award Recipient) Boston University School of Medicine 21
Jerome O. Klein, M.D. (1972 Award Recipient) Purchase of Equipment Which Will Facilitate Serum Assays in Studies Concerning Serologic Response to Infection with Genital Mycoplasma and Its Relationship to the Outcome of Pregnancy Boston Medical Center jerome.klein@bmc.org Joan H.M. Knoll, Ph.D., FACMG, FCCMG (1998 Award Recipient) Cloning a Gene Associated with Roberts Syndrome University of Western Ontario joan.knoll@schulich.uwo.ca Lazaros Kochilas, M.D. (2003 Award Recipient) Neural Crest and Cardiac Outflow Tract Development University of Minnesota kochilas@umn.edu Hetal S. Kocinsky, M.D. (2008 Award Recipient) Regulation of Proximal Tubule NHE3 by Phosphatases Pfizer New Haven CRU hetal.kocinsky@pfizer.com Ralph L. Kolodny, Ph.D. (1956 Award Recipient) Funds to provide a Community Liaison Worker to work with social agencies, clinics and hospitals toward a more effective use of existing group service resources Boston Children's Service Association Ralph L. Kolodny, Ph.D. (1965 Award Recipient) Boston Children's Service Association Boston Children's Service Association Edwin H. Kolodny, M.D. (1975 Award Recipient) Research and Development of an Automated System for Lysosomal Enzyme Assays and the Processing of Specimens for Analysis by This Method Eunice Kennedy Shriver Center, University of Massachusetts Medical School edwin.kolodny@med.nyu.edu Sek Won Kong, M.D. (2009 Award Recipient) Uncovering Molecular Targets of Histone Deacetylase Inhibitors in Cardiac Hypertrophy and Heart Failure Boston Children's Hospital swkong@enders.tch.harvard.edu Dong Kong, Ph.D. (2014 Award Recipient) Mitochondria, Cognitive Defects, and Child Obesity Tufts University School of Medicine dong.kong@tufts.edu Benjamin Kotkov, Ph.D. (1959 Award Recipient) Pilot Experiment to Provide Child Guidance Services Children's Special Services Center Stella Kourembanas, M.D. (1991 Award Recipient) Regulation of Endothelin by Oxygen Tension Boston Children's Hospital Stella.Kourembanas@childrens.harvard.edu Stephen Daniel Krasinski, Ph.D. (1993 Award Recipient) Transcriptional Regulation of Intestinal Differentiation Boston Children's Hospital stephen.krasinski@childrens.harvard.edu 22
Jordan A. Kreidberg, M.D., Ph.D. (1995 Award Recipient) The Molecular Basis of Kidney Development and Disease Boston Children's Hospital jordan.kreidberg@childrens.harvard.edu Mitchell J. Kresch, M.D. (1991 Award Recipient) Developmental Regulation of Surfactant Reuptake by Fetal Type II Cells Pennsylvania State Hershey Milton S. Hershey Medical Center mkresch@hmc.psu.edu Anton O. Kris, M.D. (1966 Award Recipient) Support of a pilot demonstration for the development and implementation of a systematic method for effective discharge planning, placement and aftercare of adolescents who are patients in mental hospitals Boston State Hospital Bernhard Kuhn, M.D. (2008 Award Recipient) Mechanisms of Cardiomyocyte Proliferation Boston Children's Hospital bernhard.kuhn@cardio.chboston.org David M. Kurnit, M.D., Ph.D. (1979 and 1980 Award Recipient) Molecular and Clinical Studies on Human Chromosome 21 University of Michigan Medical School Jake Alden Kushner, M.D. (2003 Award Recipient) Cell Cycle Regulation of Islet Growth Baylor College of Medicine kushner@bcm.edu Sau‐ping Kwan, Ph.D. (1982 Award Recipient) Studies of the Mechanism of Heavy Chain Deletion in B Cells of 'Non‐Secretory' Agammaglobulinemia Rush Medical College spkwan@rush.edu Catherine Lachenauer, M.D. (1999 Award Recipient) Mosaicism in the Alpha‐like Proteins of Group B Streptococcus Boston Children's Hospital catherine.lachenauer@childrens.harvard.edu Adam Lacy‐Hulbert, Ph.D. (2010 Award Recipient) Role of Alpha(v) Integrins in Establishment of Intestinal Immunity Massachusetts General Hospital alacy‐hulbert@partners.org Nancy Langhans, M.D. (1995 Award Recipient) Targeted Disruption of the Mouse CCK‐
B/Gastrin Receptor Greater New Bedford Community Health Center nlanghans@gnbchc.org Frederick LaRochelle, M.D., Ph.D. (1979 Award Recipient) Neurohypophyseal Response to Dehydration Stimulus During Development: Plasma and Urinary ADH (Antidiuretic Hormone) Geisel Medical School at Dartmouth Raphael Lee, M.D., Sc.D. (1983 and 1984 Award Recipient) Physical Forces in Skeletal Growth and Development: Quantification of Cellular Response University of Chicago r‐lee@uchicago.edu
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Catherine A. Lee, Ph.D. (1994 Award Recipient) Salmonella Entry into Intestinal Cells Massachusetts Institute of Technology clee2@mit.edu Mary M. Lee, M.D. (1997 Award Recipient) The Role of Mullerian Inhibiting Substance in Leydig Cell Growth University of Massachusetts Memorial Medical Center mary.lee@umassmemorial.org Wayne I. Lencer, M.D. (1988 Award Recipient) Transcellular Targeting of Cholera Toxin Boston Children's Hospital wayne.lencer@childrens.harvard.edu Paul Hubert Lerou, M.D. (2010 Award Recipient) p53 Regulation in Human Pluripotent Stem Cells Boston Children's Hospital plerou@partners.org Laurel K. Leslie, M.D., M.P.H. (2007 Award Recipient) Medication Use for Behavioral Problems Among Youth in Child Welfare Tufts Medical Center lleslie@tuftsmedicalcenter.org Donald Y.M. Leung, M.D., Ph.D. (1980 Award Recipient) Immune Mechanisms in Atopic Dermatitis (1981 Award Recipient) Immunoregulation in Kawasaki's Disease National Jewish Medical and Research Center leungd@njc.org John M. Leventhal, M.D. (1981 Award Recipient) Infant Feeding and Infectious Morbidity During the First Three Months of Life Yale School of Medicine john.leventhal@yale.edu Nancy J. Levy, Ph.D. (1984 Award Recipient) Immunotherapeutic Approaches to Group B Streptococcal Disease (1984) ‐ Expression of the C1q Receptor on Cord Blood Monocytes: Relationship to Neonatal Susceptibility to Group B Streptococcal Disease (1987 Award Recipient) Expression of the C1q Receptor on Cord Blood Monocytes: Relationships to Neonatal Susceptibility to Group B Streptococcal Disease BioHealth Management LLC nancyjlevy@biohealthmanagement.com Joanne E. Levy, M.D. (2001 Award Recipient) Genetic Studies of Mammalian Lead Absorbtion Boston Children's Hospital Ann H. Lewis, M.D. (1968 Award Recipient) To Train Attendants and Other Non‐
Professionals to Become Child Care or Mental Retardation Aides Paul A. Dever State School Leon R. Lezer, M.D. (1964 Award Recipient) Establishing an organized education and play program for pre‐school children whose presence in the outpatient clinics is incidental to the delivery of medical care for some other member of the family Boston City Hospital
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Yefu Li, Ph.D. (1996 Award Recipient) Molecular Genetic Study of Congenital Hydrocephalus Harvard School of Dental Medicine yefu_li@hsdm.harvard.edu Xue Sean Li, Ph.D. (2006 Award Recipient) Transcriptional Mechanism of the Wnt/Beta‐Catenin Signaling Pathway during Pituitary Organogenesis and Tumorigenesis Boston Children's Hospital sean.li@childrens.harvard.edu Janghoo Lim, Ph.D. (2012 Award Recipient) Molecular Pathogenesis Studies of Childhood Neurological Disorders; Rett and Angelman Syndromes Yale School of Medicine janghoo.lim@yale.edu Michael A. Linshaw, M.D. (1988 Award Recipient) Role of Extracellular Matrix in Maintenance of Renal Cell Volume Massachusetts General Hospital Myra Lipes, M.D. (1991 Award Recipient) A Transgenic Approach to Analyze Putative Autoantigens in Type I Diabetes Joslin Diabetes Center myra.lipes@joslin.harvard.edu Stuart A. Lipton, M.D., Ph.D. (1986 Award Recipient) Thy‐1 and Process Regeneration by Central Mammalian Neurons The Burnham Institute slipton@burnham.org George Lister, M.D. (1979 Award Recipient) Experimental Augmentation of Oxygen Delivery with Acute Hypoxemia Yale School of Medicine george.lister@yale.edu Zhengyu Liu, Ph.D. (2009 Award Recipient) Novel Potential Treatment for Juvenile Diabetes Sandoz Inc., a Novartis Company zhengyu.liu@sandoz.com Barry London, M.D., Ph.D. (1995 Award Recipient) A Molecular Analysis of Cardiac Automaticity University of Pittsburgh londonb@upmc.edu Christopher Y. Lu, M.D. (1988 Award Recipient) Fetoplacental Infections and the Regulation of Macrophage Function by Decidual Cells University of Texas Southwestern Medical School christopher.lu@utsouthwestern.edu Chunling Lu, Ph.D. (2013 Award Recipient) The Effectiveness of Community Financing Approach in Improving Child Nutrition Status in Rwanda. Brigham and Women's Hospital chunling_lu@hms.harvard.edu Jerold F. Lucey, M.D. (1978 Award Recipient) The Relationship of Cerebral Perfusion Pressure to Hemorrhage and Ischemic Lesions of the Prenatal Brain University of Vermont College of Medicine jerold.lucey@uvm.edu
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David S. Ludwig, M.D., Ph.D. (1995 Award Recipient) Studies on the Neuroendocrine Regulation of Obesity: a Transgenic Model of Melanin Concentrating Hormone Overexpression Boston Children's Hospital david.ludwig@childrens.harvard.edu Christina Luedke, M.D., Ph.D. (1996 Award Recipient) Reproductive Consequences of Altered Oxytocin Expression Boston Children's Hospital christina.luedke@childrens.harvard.edu William A. Lutin, M.D., Ph.D. (1988 Award Recipient) Hormonal Regulation of Rat Fetal Lung Proteins Georgia Health Sciences University wlutin@georgiahealth.edu Katherine Luzuriaga, M.D. (1991 Award Recipient) HIV‐1 Specific CTL in Pediatric Infection University of Massachusetts Medical School katherine.luzuriaga@umassmed.edu Enbo Ma, Ph.D. (1998 Award Recipient) Molecular Mechanisms of Tissue Tolerance to O2 Deprivation University of California, Berkeley enboma@uclink.berkeley.edu Mia MacCollin, M.D. (1996 Award Recipient) Genetic Analysis of Leukodystrophy Massachusetts General Hospital Rene Maehr, Ph.D. (2014 Award Recipient) Development of a Pluripotent Stem Cell‐
based Approach to Model DiGeorge Syndrome University of Massachusetts Medical School rene.maehr@umassmed.edu Jamie Lynn Maguire, Ph.D. (2010 Award Recipient) Impact of Maternal Depression on Offspring Development Tufts University School of Medicine jamie.maguire@tufts.edu James Mandell, M.D. (1976 Award Recipient) Study of the Bicuculline Response in Experimental Amblyopia Boston Children's Hospital james.mandell@childrens.harvard.edu John P. Manis, M.D. (1999 Award Recipient) Regulation of Immunoglobulin Class Switch Recombination Boston Children's Hospital manis@enders.tch.harvard.edu Leila A. Mankarious, M.D. (2000 Award Recipient) The Stenotic Trachea: a Biochemical Study of Cartilaginous and Mucosal Injury in the Human and in the Rabbit Massachusetts Eye and Ear Infirmary leila_mankarious@meei.harvard.edu Rebekah Mannix, M.D., M.P.H. (2011 Award Recipient) The Effect of Age on Outcome after Traumatic Brain Injury in Apolipoprotein E4 Carriers Boston Children's Hospital rebekah.mannix@childrens.harvard.edu
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Junhao Mao, Ph.D. (2009 Award Recipient) The Role of the Hedgehog Pathway in Childhood Rhabdomyosarcoma University of Massachusetts Medical School junhao.mao@umassmed.edu Thomas J. Maresca, Ph.D. (2013 Award Recipient) Detecting and Correcting Errors During Cell Division University of Massachusetts Amherst tmaresca@bio.umass.edu Jill Lamanna Maron, M.D., M.P.H. (2009 Award Recipient) Neonatal Salivary Genomic Profiles to Assess Gastrointestinal Development and Disease Tufts Medical Center jmaron@tuftsmedicalcenter.org Paul "Kip" Martha, M.D. (1990 Award Recipient) Specific Regulatory Effects of Gonadal Hormone on the Growth Hormone Neuroaxis Interleukin Genetics, INC. kmartha@elixirpharm.com Thomas R. Martin, M.D. (1989 Award Recipient) Cellular Elements Responsible for Allergic Broncho‐Constriction VA Puget Sound Health Care System trmartin@u.washington.edu Duncan SR Maru, M.D., Ph.D. (2014 Award Recipient) Integrating Pediatric Care Delivery in Rural Healthcare Systems Brigham and Women's Hospital duncan@possiblehealth.org Benedict F. Massell, M.D. (1954 Award Recipient) Rheumatic Fever Study Alan N. Mayer, M.D., Ph.D. (2002 Award Recipient) Molecular Basis of Organogenesis: Isolation of Npo Associated Proteins and RNA Medical College of Wisconsin alanm@wigia.com Chaim I. Mayman, M.D. (1972 Award Recipient) Research Toward Studying the Activity of Enzymes Concerned with Cerebrospinal Fluid Formation in Newborn and Developing Animals to Help Improve the Treatment of Hydrocephalus in Children Beth Israel Deaconess Medical Center Irina Mazo, M.D., Ph.D. (2003 Award Recipient) The Immunocompetent Cell Migration to the Bone Marrow Immune Disease Institute irina.mazo@childrens.harvard.edu James McGrath, M.D., Ph.D. (1994 Award Recipient) Genomic Imprinting Yale School of Medicine james.mcgrath@yale.edu Kenneth McIntosh, M.D. (1984 Award Recipient) Respiratory Syncytial Virus: Epidemiology and Immunologic Response Boston Children's Hospital kenneth.mcintosh@childrens.harvard.edu Donald E. McKay, M.D. (1953 Award Recipient) Pregnancy Toxemia 27
R. James McKay, M.D. (1962 Award Recipient) Funds to Assist the New Teaching Program in Human Genetics in Becoming Soundly Established University of Vermont College of Medicine Marion McKee (1963 Award Recipient) An evaluation survey of families, social and medical agencies, and physicians to determine the effectiveness of the present mental retardation program and to gain insights and directions for a program which will assist children who are mentally retarded Vermont Department of Health David McKenney, Ph.D. (2000 Award Recipient) Immunoprophylaxis of Staphlococcus Aureus Infections in Neonates Paratek Pharmaceuticals dmckenney@paratekpharm.com James T. McLaughlin, Ph.D. (1996 Award Recipient) In Vitro and In Vivo Models of Cushing's Disease: Calcium University of North Carolina at Chapel Hill jim.mclaughlin@unc.edu Katie Anne McLaughlin, Ph.D. (2012 Award Recipient) Neurobiological Mechanisms Linking Adverse Childhood Experiences to Adolescent Mental Disorders Boston Children's Hospital katie.mclaughlin@childrens.harvard.edu Robert H. McLean, M.D. (1974 Award Recipient) Isolation and Characterization of a C3 Activating Serum Factor and its Role in Human Glomerulonephritis University of Connecticut Health Center James G. McNamara, M.D., M.S. (1990 Award Recipient) Analysis of T‐cell Clones During Human Development National Institute of Allergy and Infectious Diseases jm74q@nih.gov Alison L. Meadows, M.D., Ph.D. (2006 Award Recipient) Novel Computational Modeling of Dynamic Afterload and Ventriculo‐arterial Coupling in Coarctation of the Aorta University of California, San Francisco Joan Mecsas, Ph.D. (2001 Award Recipient) Role of Yersinia Yops in Causing Diarrheal Disease Tufts University School of Medicine joan.mecsas@tufts.edu Laura R. Ment, M.D. (1981 Award Recipient) Cerebral Blood Flow and Metabolism in the Beagle Puppy Model of Intraventricular Hemmorhage (IVH) (1981) ‐ Fine Structure of Intraventricular Hemmorhage (1982) Yale School of Medicine laura.ment@yale.edu Ezio Merler, Ph.D. (1979 Award Recipient) Immunoregulation by a New Physiological Suppressor Substance Boston Children's Hospital 28
Simon K. Michael, M.D., Ph.D. (1999 Award Recipient) Following Cell Fate in the Living Mouse Embryo Tufts Medical Center smichael@tuftsmedicalcenter.org Laurie C. Miller, M.D. (1991 Award Recipient) Regulation of Human IL‐1 and IL‐1ra Gene Expression by Borrelia Burgdorferi Tufts Medical Center lmiller1@tuftsmedicalcenter.org Tracie Lee Miller, M.D. (1992 Award Recipient) Nutritional Evaluation of HIV‐Infected Children University of Miami School of Medicine tracie.miller@miami.edu Anthony B. Minnefor, M.D. (1956 Award Recipient) Development of Vaccine for Human Cytomegalovirus University of Vermont College of Medicine Anthony B. Minnefor, M.D. (1970 Award Recipient) Vaccine against Human Cytomegalovirus University of Vermont College of Medicine Lisa Mary Minter, Ph.D. (2009 Award Recipient) Targeting NF‐kappaB Signaling in a Murine Model of Acquired Aplastic Anemia University of Massachusetts Amherst lminter@vasci.umass.edu Deborah C. Molrine, M.D., M.P.H. (1997 Award Recipient) The Effect of Anti‐Sialidase Antibody in a Murine Model of RSV Infection University of Massachusetts Medical School deborah.molrine@umassmed.edu Paul Moore, M.D. (2000 Award Recipient) B2‐Adrenergic Receptor Polymorphisms Influence Desensitization Vanderbilt University Medical Center paul.moore@vanderbilt.edu Melinda J. Morin, M.D. (2001 Award Recipient) Mechanisms of MF‐kB and MAPK Signal Transduction in Endotoxin Tolerance Boston Children's Hospital mmorin@childrens.harvard.edu C.F.A. Morrees, D.M.D. (1947 Award Recipient) Research in Growth and Development of Teeth and Jaws Katherine M. Morris, Ph.D. (1979 Award Recipient) The Genetic Mechanism of Hereditary Angiodema: Regulation of C1 Inhibitor Synthesis In Vitro Immune Disease Institute Eric Matthew Morrow, M.D., Ph.D. (2007 Award Recipient) Genetic Investigation of Cognitive Development in Autistic Spectrum Disorders Massachusetts General Hospital Eric_Morrow@brown.edu 29
Keith E. Mostov, M.D., Ph.D. (1985 Award Recipient) Receptor‐mediated Transport of Immunoglobin G in Neonatal Rat Intestines and Human Placenta University of California San Francisco mostov@itsa.ucsf.edu Fernando R. Moya, M.D. (1985 Award Recipient) Acceleration of Fetal Lung Maturation by Administration of Dexamethasone and Thyrotropin‐Releasing Hormone (TRH) to the Pregnant Rabbit University of Texas Health Science Center at Houston Susan Moyer, M.D. (1989 Award Recipient) Ontogeny of Intestinal Taurine Transport Cincinnati Children's Hospital Medical Center Lars Ulf Werner Mueller, M.D. (2009 Award Recipient) Validation of Disease‐specific Fanconi Anemia Induced Pluripotent Stem (iPS) Cells a Tool for Studying Bone Marrow Failure and Enabling Regenerative Medicine Genentech mueller.lars@gene.com Louis J. Muglia, M.D., Ph.D. (1993 Award Recipient) The Function and Regulation of Corticotropin Releasing Hormone Vanderbilt University Medical Center louis.muglia@vanderbilt.edu Noritsugu Mukai, M.D. (1974 Award Recipient) For the Further Understanding, Prevention and Treatment of Retinoblastoma Schepens Eye Research Institute
Paul L. Munson, M.D. (1954 Award Recipient) Calcium Concentration of Milk Thomas Scot Murray, M.D., Ph.D. (2010 Award Recipient) The Role of Lactate Metabolism in Pseudomonas Aeruginosa Biofilm Formation Yale School of Medicine thomas.s.murray@yale.edu Linda L. Nardone, Ph.D. (1977 Award Recipient) Effects of Antibiotics on Surfactant Synthesis and Secretion Yale School of Medicine lnardone@elusys.com David G. Nathan, M.D. (1969 Award Recipient) Biochemical Control of Severe Thalassemia Dana‐Farber Cancer Institute david_nathan@dfci.harvard.edu Eugene F. Nattie, M.D. (1979 Award Recipient) Brain and Cerebrospinal Fluid Acid‐Base and Electrolyte Balance in the Newborn Puppy During Hypo‐ and Hypernatremia Geisel Medical School at Dartmouth eugene.nattie@dartmouth.edu Eugene F. Nattie, M.D. (June 1980 Award Recipient) Brain and Cerebrospinal Fluid Acid‐Base and Electrolyte Balance in the Newborn Puppy During Hypo‐ and Hypernatremia Geisel Medical School at Dartmouth eugene.nattie@dartmouth.edu 30
Victor M Navarro, Ph.D. (2014 Award Recipient) The Role of Tachykinins in the Central Control of Sexual Maturation: Implications for the Timing of Puberty Brigham and Women's Hospital vnavarro@partners.org Ellis J. Neufeld, M.D., Ph.D. (1992 Award Recipient) Molecular Basis of the Syndrome of TRADD Boston Children's Hospital ellis.neufeld@childrens.harvard.edu Ann Neumeyer, M.D. (1995 Award Recipient) Myoblast Fusion and Implantation Massachusetts General Hospital aneumeyer@partners.org Peter E. Newburger, M.D. (1982 and 1983 Award Recipient) Function and Differentiation of Phagocytes in Hematologic Disorders University of Massachusetts Medical School peter.newburger@umassmed.edu Peter Andrija Nigrovic, M.D. (2009 Award Recipient) Neutrophil Recruitment in Inflammatory Arthritis Brigham and Women's Hospital pnigrovic@partners.org Lise Edelberg Nigrovic, M.D., M.P.H. (2010 Award Recipient) Development and Pilot Testing of a Computerized Decision Rule for Children with Minor Blunt Head Trauma Boston Children's Hospital lise.nigrovic@childrens.harvard.edu Abraham E. Nizel, D.M.D. (1969 Award Recipient) Biomedical Study of Young People Who Suffer from Rampant Dental Caries Tufts University School of Dental Medicine Hans C. Oettgen, M.D., Ph.D. (1994 Award Recipient) Genetic Analysis of the Function of IgE in Allergic Pathology Boston Children's Hospital hans.oettgen@childrens.harvard.edu William Oh, M.D. (1974 Award Recipient) Clinical Studies on the Feeding of Alanine Toward the Prevention of Neonatal Hypoglycemia in Infants with Intrauterine Growth Retardation Women & Infants Hospital of Rhode Island william_oh@brown.edu Tihamer Orban, M.D. (1998 Award Recipient) Autoantigen Vaccination in Human Type 1 Diabetes Mellitus Joslin Diabetes Center tihamer.orban@joslin.harvard.edu Roslyn W. Orkin, Ph.D. (1983 Award Recipient) Role of Hyaluronidase in Morphogenesis and Tissue Remodeling Harvard Medical School roslyn_orkin@hms.harvard.edu John S. O'Shea, M.D. (1977 Award Recipient) Treatment of Serous Otitis Media Rhode Island Hospital 31
Sung‐Yun Pai, M.D. (2006 Award Recipient) Genome‐wide Identification of GATA3 Targets in Thymus Boston Children's Hospital sung‐yun.pai@childrens.harvard.edu In‐Hyun Park, Ph.D. (2010 Award Recipient) Investigation of Functional Myogenic Progenitors from Human ES and iPS Cells for Duchenne Muscular Dystrophy Yale School of Medicine inhyun.park@yale.edu Mark A. Parker, Ph.D. (2006 Award Recipient) Engineering Neural Stem Cells to Develop along a Cochlear Pathway Massachusetts Eye and Ear Infirmary mark_parker@meei.harvard.edu Mark S. Pasternack, M.D. (1983 Award Recipient) Analysis of Cell‐Mediated Immunity in Experimental Respiratory Syncytial Virus Infection Massachusetts General Hospital mpasternack@partners.org Rupal Patel, Ph.D. (2004 Award Recipient) Harnessing Residual Vocal Control in Children with Severe Speech Impairment Northeastern University r.patel@neu.edu Eleanor Pavenstedt, M.D. (1967 Award Recipient) Establishment of an Infants and Toddlers Unit in the Mental Health Intervention Program, Initiated in the Columbia Point Health Center Tufts University School of Medicine
David H. Perlmutter, M.D. (1985 Award Recipient) The Biochemical Defect in PiZ Alpha‐1 Antitrypsin Deficiency (1986 Award Recipient) The Biochemical Defect in Alpha‐1 Antitrypsin Deficiency II Children's Hospital of Pittsburgh perldav@chp.edu Maurice J. Pescitelli, Ph.D. (1988 Award Recipient) The Relationship Between Early Vascular Development and the Occurrence of Limb and Visceral Malformations Caused by Dominant Hemimelia in Mice University of Illinois College of Medicine mjpesci@uic.edu Georges Peter, M.D. (1978 and 1979 Award Recipient) Gram‐negative Bacteremia in Children with Malignancies Rhode Island Hospital David S. Phelps, Ph.D. (1986 Award Recipient) Characterization and Quantitation of Low Molecular Weight Proteins in Human Pulmonary Surfactant The Pennsylvania State University College of Medicine dsp4@psu.edu 32
Anthony Philipps, M.D. (1977 Award Recipient) Fetal Insulin Secretion and Glucose Utilization (1978 Award Recipient) Metabolic Effects of Fetal Endogenous Insulin Secretion University of California, Davis Medical Center a.philipps@ucdmc.ucdavis.edu Harry I. Phillips, M.D. (1960 Award Recipient) Pilot project in the Newton School Health Service, designed toward developing a ndw program for school physicians which will change their role from that of a "medical inspector" to that of a "school medical advisor" Newton Board of Health Chanika Phornphutkul, M.D. (2005 Award Recipient) Chondrogenesis and Long Bone Growth Rhode Island Hospital Chanika_Phornphutkul@brown.edu Xianhua Piao, M.D., Ph.D. (2004 Award Recipient) The Genetics of Bilateral Frontoparietal Polymicrogyria and Epilepsy Boston Children's Hospital xianhua.piao@childrens.harvard.edu Gerald B. Pier, Ph.D. (1985 Award Recipient) Prevention of Coagulase‐negative Staphylococcal Infections of Indwelling Catheters and Prosthetic Devices Brigham and Women's Hospital gpier@rics.bwh.harvard.edu Emese Pinter, M.D. (1999 Award Recipient) Hyperglycemia‐Induced Vasculopathy in the Murine Conceptus: the Role of PECAM‐1 Modulated Catenin/Cadherin Interactions During Endothelial Tube Formation Yale School of Medicine emese.pinter@yale.edu Bruce R. Pitt, Ph.D. (1981 Award Recipient) Pulmonary Metabolic Function in the Awake Lamb: Effect of Hypoxia and Development University of Pittsburgh Graduate School of Public Health brucep@pitt.edu Stephen C. Porter, M.D., M.P.H. (2002 Award Recipient) Informative Technology Linking Parents and Providers University of Toronto stephen.porter@sickkids.ca George A. Porter, M.D., Ph.D. (2006 Award Recipient) Calcium Channels Regulate the Formation of the Cardiac Outflow Tract from the Anterior Heart Field University of Rochester Medical Center george_porter@urmc.rochester.edu Tara Pouyani, Ph.D. (2005 Award Recipient) Development of a Novel Skin Substitute to Promote Dermal Regeneration Northeastern University t.pouyani@neu.edu Dane G. Prugh, M.D. (1954 Award Recipient) Brenton Unit for Psychological Pediatrics Boston Children's Hospital 33
William T. Pu, M.D. (2000 Award Recipient) Csx and GATA4 Cardiac Transcription Factors in Myocardial Hypertrophy Boston Children's Hospital wpu@enders.tch.harvard.edu Karen Puopolo, M.D., Ph.D. (2004 Award Recipient) Mechanisms of Transcriptional Regulation and Genetic Recombination in Group B Streptococcus Brigham and Women's Hospital kpuopolo@partners.org Elizabeth Quackenbush, M.D., Ph.D. (1998 Award Recipient) Development of a Novel Model of Intravital Microscopy to Examine Fetal Cell Migration Merck & Company, Inc. Paula Quatromoni, D.Sc. (2007 Award Recipient) Evaluating IMOVE: An Environmental Intervention to Promote Healthy Eating in Middle‐School Children from Massachusetts Communities at High Risk for Childhood Obesity Sargent College of Health and Rehabilitation Sciences, Boston University paulaq@bu.edu Lawrence F. Quigley, D.M.D. (1964 Award Recipient) Research Designed for the Evaluation of Reconstructive Surgery in Cleft Palate Patients The Forsyth Institute Narayanaswamy Ramesh, Ph.D. (1993 Award Recipient) Analysis of Gamma/Delta T‐cell Activation by Superantigens and in Juvenile Rheumatoid Arthritis Boston Children's Hospital narayanaswamy.ramesh@childrens.harvard.edu John R. Raye, M.D. (1973 Award Recipient) Effects of Uterine Vascular Obstruction on Fetal Nutrient Supply (1981 Award Recipient) Effect of Caffeine Exposure during Pregnancy on Growth and Behavioral Development: I. Characterization of Pharmacokinetics and Effects on Pregnancy in Rabbit Model University of Connecticut Health Center jraye@att.net Duncan E. Reid, M.D. (1949 Award Recipient) Metabolic Changes during Pregnancy Brigham and Women's Hospital Steven Reppert, M.D. (1980 Award Recipient) Postnatal Maternal Influence on Circadian Periodicity in the Rat University of Massachusetts Medical School Steven.Reppert@umassmed.edu Elizabeth P. Rice, A.M., S.M. (1953 Award Recipient) Funds to employ a social worker for the Child Health Clinic at the Bromley Park and Health Housing Project in cooperation with HSPH and the Boston Health Department Harvard School of Public Health 34
R. Gerald Rice, M.D., M.P.H. (1953 Award Recipient) Accident Prevention Among Children: a Pilot Study Elizabeth P. Rice, A.M., S.M. (1960 Award Recipient) Family Health Clinic Harvard School of Public Health Peter Rice, M.D. (1979 and 1981 Award Recipient) Immunologic and Chemical Studies of Non‐
typable Haemophilus Influenzae in Children with Otitis Media University of Massachusetts Medical School peter.rice@umassmed.edu Michael Ogden Rich, M.D., M.P.H. (2005 Award Recipient) VIA ‐ Overweight and at Risk (OAR) Boston Children's Hospital kristelle.lavallee@childrens.harvard.edu Tracy K. Richmond, M.D., M.P.H. (2007 Award Recipient) School Physical Activity Programs' Contribution to Racial/Ethnic Disparities in Adolescent Physical Activity and Obesity Boston Children's Hospital tracy.richmond@childrens.harvard.edu Leona L. Riskin, A.S.W. (1960 Award Recipient) Support of a Prep Club Project which would provide opportunities for high school students from economically deprived areas to explore careers in social work Robert F. Ritchie, M.D. (1969 Award Recipient) Automation of Multiple Plasma Protein Immunoassays for Pediatric Patients Maine Medical Center ritchie@fbr.org Stanley L. Robbins, M.D. (1947 Award Recipient) Study of Renal Damage in Diabetes Boston University School of Medicine Charles W. M. Roberts, M.D., Ph.D. (2003 Award Recipient) Identifying Transcriptional Targets of the Snf5 Tumor Suppressor in Aggressive Pediatric Cancer Dana‐Farber Cancer Institute charles_roberts@dfci.harvard.edu Reginald Robinson, Ph.D. (1960 Award Recipient) Support of the Program of the Massachusetts Committee on Children and Youth Massachusetts Committee on Children and Youth Seymour L. Romney, M.D. (1953 Award Recipient) Pregnancy Toxemia Fred S. Rosen, M.D. (1966 Award Recipient) Prevention of Warm Hemolysis by the IgG Effector Site for the Monocyte Receptor Boston Children's Hospital rosen@cbr.med.harvard.edu (1967 Award Recipient) Prep Club Project Social Work Careers Program 35
Robert G. Rosenberg, M.D. (1970 Award Recipient) To Establish a Self‐Supporting Pediatric Service Martha Eliot Health Center rgrosenberg2@hotmail.com Ted S. Rosenkrantz, M.D. (1983 Award Recipient) Cerebral Metabolism of Glucose and Non‐
Glucose Substrates in the Newborn Lamb with Polychythemia University of Connecticut Health Center rosenkrant@nso1.uchc.edu N. Paul Rosman, M.D. (1969 Award Recipient) The Influence of Early‐Life Hypothyroidism (Cretinism) on Developing Brain and Skeletal Muscle (1974 Award Recipient) Clinical Studies on the Fetal Alcohol Syndrome (1976 Award Recipient) Maternal Alcohol Intake and Fetal Development: A Laboratory Model Boston University School of Medicine paul.rosman@bmc.org David W. Rowe, M.D. (1977 Award Recipient) Mechanisms of Growth Inhibition by Glucocorticoids University of Connecticut Health Center rowe@neuron.uchc.edu Jonelle C. Rowe, M.D. (1979 Award Recipient) Phosphorus Accretion in Small Premature Infants Fed Human Milk or Proprietary Formula University of Connecticut Health Center jrowe@osophs.dhhs.gov
David Rowitch, M.D., Ph.D. (1997 Award Recipient) Ectopic Expression of Sonic Hedgehog in the CNS of Transgenic Mice University of California San Francisco rowitchd@peds.uscf.edu Paul A. Rufo, M.D., M.M.Sc. (1997 Award Recipient) Inhibition of Intestinal Cl‐Secretion by Clotrimazole and Related Triphenyl Derivatives Boston Children's Hospital paul.rufo@childrens.harvard.edu William E. Russell, M.D. (1985 Award Recipient) Type Beta Transforming Growth Factor as a Physiologic Regulator of Liver Growth (1987 Award Recipient) Transforming Growth Factor Beta (TGF‐B) and Related Peptides as Physiologic Regulators of Liver Growth Vanderbilt University Medical Center bill.russell@vanderbilt.edu Gary J. Russell, M.D. (1988 Award Recipient) Biology of Mucosal Lymphocytes and Their Role in Celiac Disease Massachusetts General Hospital grussell@partners.org Myra M. Sampson, M.S.W. (1952 Award Recipient) The Effects of Deficiency and of Excess of Calcium Smith College 36
Ian R. Sanderson, M.D. (1995 Award Recipient) The Role of Dietary Constituents on the Expression of Genes in the Intestinal Epithelium that Influence Inflammation Barts and the London School of Medicine and Dentistry i.r.sanderson@mds.qmw.ac.uk Alfred Sandrock, M.D., Ph.D. (1997 Award Recipient) Pathogenesis of Spinal Muscular Atrophy (SMA): Role of SMN Protein in Motor Neuron Survival Biogen Idec alfred.sandrock@biogenidec.com Christopher Sassetti, Ph.D. (2007 Award Recipient) Virulence Gene Regulation in Mycobacterium Tuberculosis University of Massachusetts Medical School christopher.sassetti@umassmed.edu Carol Ann Satler, M.D., Ph.D. (1994 Award Recipient) Genetic Analysis of New England Children at Risk for Sudden Death from Hereditary Long QT Syndrome Indigo Pharmaceuticals Jessica Savage, M.D. (2014 Award Recipient) Environmental Antimicrobial Chemicals and Allergic Disease Brigham and Women's Hospital jrsavage@partners.org Barry S. Schifrin, M.D. (1973 Award Recipient) Support Research Toward Evaluating the Accuracy of Fetal Heart Rate Patterns in Predicting Subsequent Fetal and Neonatal Compromise Beth Israel Deaconess Medical Center bpminc@aol.com Christian Dirk Schlieker, Ph.D. (2010 Award Recipient) Investigating Nuclear Envelopathies from the Perspective of Protein Quality Control Yale University christian.schlieker@yale.edu Susanne Schlisio, Ph.D. (2007 Award Recipient) Neuronal Apoptosis by EgIN3 and the 1p36 Gene KIF1BBeta: Implication in Neuroblastoma Development Karolinska Institutet susanne.schlisio@licr.ki.se Emmett Schmidt, M.D., Ph.D. (1993 Award Recipient) Gene Therapy Using Receptor‐Mediated Endocytosis of Soluble DNA Complexes Massachusetts General Hospital schmidt@helix.mgh.harvard.edu Valerie Anne Schumacher, Ph.D. (2012 Award Recipient) A Role for Staufen 2‐Containing RNA Granules in Chronic Kidney Disease Boston Children's Hospital valerie.schumacher@childrens.harvard.edu 37
Jerrold Schwaber, Ph.D. (1979 and 1980 Award Recipient) Cellular Differentiation in x‐linked Agammaglobulinemia (1981 Award Recipient) Regulation of Immunoglobulin Secretion in Agammaglobulinemia Boston Children's Hospital Robert Schwartz, M.D. (1975 Award Recipient) Kinetic Studies of Glucose Metabolism in Infants with Isotopically Stable Glucose 13c Rhode Island Hospital Alan L. Schwartz, M.D., Ph.D. (1982 and 1983 Award Recipient) Structure and Function of the Human Receptor for Asialoglycoproteins Washington University School of Medicine in St. Louis schwartz@kids.wustl.edu William J. Schwartz, M.D., Ph.D. (1982 Award Recipient) Canine Narcolepsy: Role of the Suprachiasmatic Nucleus University of Massachusetts Medical School william.schwartz@umassmed.edu A. Nicola Schweitzer, Ph.D. (1998 Award Recipient) Neonatal Immune Responses to Immunization: a T Cell Receptor (TCR)‐
Transgenic Approach Brigham and Women's Hospital mschweitzer@mac.com Nevin S. Scrimshaw, M.D., Ph.D. (1976 Award Recipient) Nutritional Requirements of Children with Chronic Renal Insufficiency International Nutrition Foundation nscrimshaw@inffoundation.org Rose Segal, M.S.W. (1967 Award Recipient) Exploratory Study Concerning Behavioral Characteristics of Abusing and Neglecting Parents in Relation to the "Battered Child" Phenomena Boston University School of Social Work Michael Segal, M.D., Ph.D. (1995 Award Recipient) Sodium Channel Charges in Hypoxic Seizures in Slices and Cultures Simul Consult 2012@simulconsult.com Stephanie Seminara, M.D. (2002 Award Recipient) Establishing the Genetic Basis for Hypogonadrotropic Hypogonadism Massachusetts General Hospital seminara.stephanie@mgh.harvard.edu Sarbattama Sen, M.D. (2013 Award Recipient) BMI‐Based Prenatal Vitamins to Ameliorate Oxidative Stress in Obese Pregnancy Tufts Medical Center ssen@tuftsmedicalcenter.org Boris Senior, Ph.D., FRCP (1969 Award Recipient) Formation of Triglycerides by the liver of Hyperinsulinemic Obese Subjects Tufts Medical Center bodosen@comcast.net 38
Linda B. Shalon, M.D. (1997 Award Recipient) The Differentiation Repertoire of Pancreatic Oval Cells Rhode Island Hospital lshalon@lifespan.org Daniel C. Shannon, M.D., M.A. (1972 Award Recipient) Evaluation of Intermittent Positive Pressure Breathing Treatments in Children Massachusetts General Hospital dshannon@partners.org Donald L. Shapiro, M.D. (1975 and 1976 Award Recipient) A Study of Erythrocyte Membrane Lipids of Premature and Abnormal Newborn Infants Yale School of Medicine Bennett A. Shaywitz, M.D. (1975 Award Recipient) Brain Catecholamines and Minimal Brain Dysfunction Yale School of Medicine bennett.shaywitz@yale.edu Qichang Shen, Ph.D. (1994 Award Recipient) Glutathione Peroxidase and Experimental Diabetes University of Massachusetts Medical School qichang.shen@umassmed.edu Gordon F. Sherman, Ph.D. (1986 Award Recipient) Mechanisms of Asymmetry in the Rat Brain: Implications for Understanding Dyslexia Newgrange School and Educational Outreach Center gsherman@thenewgrange.org Hai Ning Shi, D.V.M., Ph.D. (2001 Award Recipient) The Induction of Intestinal Inflammation: Role of Luminal Bacterial Antigen Massachusetts General Hospital shiha@helix.mgh.harvard.edu Norman J. Siegel, M.D. (1974 and 1975 Award Recipient) Studies on the Mechanisms Involved in Obstructive Nephropathy (1976 Award Recipient) The Recovery Process in Acute Renal Injury Yale School of Medicine norman.siegel@yale.edu Michael Silverstein, M.D., M.P.H. (2008 Award Recipient) Empowering Low‐Income Depressed Mothers with Preterm Infants: A Randomized Controlled Trial Boston Medical Center michael.silverstein@bmc.org Katherine Sims, M.D. (1993 Award Recipient) Norrie Disease Gene and Protein: Role in Congenital Blindness and Retinal Development Massachusetts General Hospital sims@helix.mgh.harvard.edu David A. Sinclair, Ph.D. (2000 Award Recipient) The Role of Mobile DNA Repair Proteins and ATM in the Development of Childhood Leukemias Harvard Medical School david_sinclair@hms.harvard.edu 39
James Skare, Ph.D. (1986 Award Recipient) Localization of the Mutation Causing X‐
Linked Lymphoproliferative Syndrome Boston University School of Medicine David Skurnik, M.D., Ph.D. (2011 Award Recipient) Broad‐Spectrum Immunoprophylaxis and Therapy for Bacterial Meningitis in Neonates Brigham and Women's Hospital dskurnik@rics.bwh.harvard.edu Clement B. Sledge, M.D. (1972 Award Recipient) Control Mechanisms of Epiphyseal Cartilage Growth in Children Harvard Medical School cbsledge@comcast.net Eleanor H. Smith, M.D., M.P.H. (1960 Award Recipient) Accident Prevention Program for Children Nashoba Associated Boards of Health David H. Smith, M.D. (1970 Award Recipient) Prevention of Infections Due to the Influenza Bacillus Boston Children's Hospital Arnold L. Smith, M.D. (1975 Award Recipient) Cerebral Metabolism During Meningitis Boston Children's Hospital arnold.smith@sbri.org Lois E. Smith, M.D., Ph.D. (1984 Award Recipient) The Role of Dopamine in Heritable Retinal Degenerations Boston Children's Hospital lois.smith@childrens.harvard.edu Gromoslaw A. Smolen, Ph.D. (2009 Award Recipient) Novel Regulators of Epithelial‐to Mesenchymal Transition (EMT) Massachusetts General Hospital gsmolen@partners.org Robert Snodgrass, M.D. (1976 Award Recipient) Study of Biculine Response in Experimental Ambylopia Boston Children's Hospital rsnodgrass@chla.usc.edu Evan Y. Snyder, M.D., Ph.D. (1994 Award Recipient) Are Immortalized Neural Progenitors a Feasible Strategy for Gene Therapy and Repair in the Human?: Groundwork Studies The Burnham Institute esnyder@burnham.org Merav Socolovsky, MBBS, Ph.D. (2004 Award Recipient) Flow Cytometric Analysis of Erythroid Progenitors In Vivo University of Massachusetts Medical School merav.socolovsky@umassmed.edu Alexander A. Soukas, M.D., Ph.D. (2011 Award Recipient) Obesity and Diabetes Genetics in C. elegans and Mice Massachusetts General Hospital asoukas@chgr.mgh.harvard.edu Igor Splawski, Ph.D. (2005 Award Recipient) Calcium Channels in Arrhythmia and Autism Boston Children's Hospital Igor@enders.tch.harvard.edu 40
Nancy Staver, M.S.W. (1970 Award Recipient) Seminars for Social Workers to Increase Their Knowledge About Poor Inner City Children and Their Families Judge Baker Children's Center Kimberly Stegmaier, M.D. (2005 Award Recipient) Chemical Genomic Approaches for Pediatric Leukemia Dana‐Farber Cancer Institute Kimberly_Stegmaier@dfci.harvard.edu Suzanne F. Steinbach, M.D. (1987 Award Recipient) A Molecular Genetic Study of Pseudomonas Aeruginosa Receptor Binding in Cystic Fibrosis Lung Infection Boston Medical Center steinbch@bu.edu Jurgen Steinke, M.D. (1965 Award Recipient) In Support of Exploratory Research which is Concerned with the Severe Problems of Anti‐
Rh Sensitization in Relation to the Problems of Infants from Mothers with Diabetes Mellitus Harvard Medical School Leon Stemfel, M.D. (1960 Award Recipient) Funds used for a detailed examination of the causes of perinatal and infant mortality during the past decade in an effort to identify areas of possible preventive action Cambridge Health Department Barbara S. Stonestreet, M.D. (1978 and 1979 Award Recipient) The Effects of Asphxia and Hypotension on Physiologic and Anatomic Renal Parameters in the Prematurely Delivered Lamb Women & Infants Hospital of Rhode Island bstonest@wihri.org Robert C. Storrs, M.D. (1963 Award Recipient) To Help Initiate a Clinical Center to Detect, Define and Treat Inherited Disorders Dartmouth‐Hitchcock Medical Center Harold Stuart, M.D. (1951 Award Recipient) Fellowships in Maternal and Child Health Harvard School of Public Health John Sullivan, M.D. (1978 Award Recipient) Cell Mediated Immunity During Epstein‐Barr Virus (EBV) and Cytomegalovirus (CMV) Induced Mononucleosis University of Massachusetts Medical School John.Sullivan@umassmed.edu John B. Susa, Ph.D. (1977 Award Recipient) A Model for Hyperinsulinemia in the Primate (Rhesus) Fetus Rhode Island Hospital john_susa@brown.edu Kotaro Suzuki, M.D., Ph.D. (1973 Award Recipient) Study of Lung Tracheal Fluid of the Primate Fetus toward Developing Scientific Basis for Intrauterine Diagnosis of Fetal Lung Maturity Beth Israel Deaconess Medical Center 41
H. William Taeusch, M.D. (1974 Award Recipient) Research Toward Determining if Lung Volume or Hypoxemia is the Initiating Stimulus for Periodic Breathing and Apneic Spells in Premature Infants (1980 Award Recipient) Fetal Surfacant Protein in Diabetic Pregnancy University of California, San Francisco btaeusch@sfghpeds.ucsf.edu Michael E. Talkowski, Ph.D. (2013 Award Recipient) Prospective Study of Genomic Aberrations during Prenatal Gestation Massachusetts General Hospital talkowski@chgr.mgh.harvard.edu Norman S. Talner, M.D. (1978 Award Recipient) The Effect of Physical Training on Exercise Performance in Post‐Operative Patients with Congenital Heart Disease Duke University Medical Center ntalner@mindspring.com James E. Teele, Ph.D. (1968 Award Recipient) To Assess the Management and Child Care Problems Experienced by Unwed Mothers in Order to Identify Implications for Program Planning Among Health, Welfare and Social Agencies Harvard School of Public Health jteele@bu.edu Hans‐Lukas Teuber, Ph.D. (1969 Award Recipient) Learning Disorders in Children Massachusetts Institute of Technology John F. Thompson, M.D. (1987 Award Recipient) Breastmilk‐stimulated Intestinal Growth University of Miami School of Medicine Cheleste M. Thorpe, M.D., A.M. (2000 Award Recipient) Shiga Toxin Effects on Gene Regulation Tufts Medical Center cthorpe@tuftsmedicalcenter.org Baruch S. Ticho, M.D., Ph.D. (1995 Award Recipient) Transgenic Analysis of Cardiac Transcription Factors in Zebrafish Massachusetts General Hospital Philip Tolzis, M.D. (1986 Award Recipient) Effect of Ribavirin on Macromolecular Synthesis of Vesicular Stomatitis Virus Case Western Reserve University School of Medicine pxt2@po.cwru.edu Hung Ton‐That, Ph.D. (2005 Award Recipient) Group B Streptococcal Pill: Assembly and Their Role in Neonatal Disease University of Connecticut Health Center ton‐that@uchc.edu William Tse, M.D., Ph.D. (2003 Award Recipient) Developing Stem Cell Transplantation as a Cure of Cardiomyopathy Northwestern University Feinberg School of Medicine w‐tse@northwestern.edu 42
Yi‐Tang Tseng, Ph.D. (2002 Award Recipient) Mechanisms of Glucocorticoid‐Induced Hypertrophy in the Developing Heart Women & Infants Hospital of Rhode Island yi‐tang_tseng@brown.edu Brian S. Tseng, M.D., Ph.D. (2008 Award Recipient) Creatine Pathways: Novel Treatments for Duchenne Muscular Dystrophy Massachusetts General Hospital briantseng@partners.org Yasuyoshi Ueki, M.D., Ph.D. (2007 Award Recipient) Role of SH3BP2 as a Novel Regulator of TNF‐
alpha Production and Osteoclastogenesis University of Missouri‐Kansas City uekiy@umkc.edu Dale T. Umetsu, M.D., Ph.D. (1985 Award Recipient) Regulation of IgE Synthesis in Children Boston Children's Hospital dale.umetsu@childrens.harvard.edu Brent Upchurch, M.D. (1993 Award Recipient) The Role of the Peptide YY Cell in the Differentiation of Pancreatic Islet Cells Signature Health Care bhupchurch@bgpma.com Bert L. Vallee, M.D. (1952 Award Recipient) Study of the Distribution and the Function of Trace Metals in Biological Systems Brigham and Women's Hospital Stephen David Van Hooser, Ph.D. (2013 Award Recipient) The Impact of Genes and Experience on the Development of Brain Circuits Brandeis University vanhoosr@brandeis.edu Scott K. Van Why, M.D. (1993 Award Recipient) Molecular Mechanisms of Recovery from Renal Ischemia Medical College of Wisconsin svanwhy@mcw.edu Samuel Varghese, Ph.D. (1996 Award Recipient) Regulation of Collagenase Gene by Retinoic Acid in Bone St. Francis Hospital and Medical Center svarghes@stfranciscare.org Donata Vercelli, M.D. (1990 Award Recipient) Molecular Mechanisks of E‐Switching in Human B Cells Arizona University donata@resp‐sci.arizona.edu Menno Verhave, M.D. (1990 Award Recipient) Regulation of Somatostatin Gene Transcription by Second Messengers Boston Children's Hospital menno.verhave@childrens.harvard.edu Thomas B. Waggener, Ph.D. (1989 Award Recipient) Program for Research Training Grant Physio Analytics twaggener@physioanalytics.com 43
Richard Wagner, M.D. (1965 Award Recipient) Funds toward completion of a scientific biography concerning Dr. Clemens von Pirquet Floating Hospital for Children at Tufts Medical Center Joseph Wagstaff, M.D., Ph.D. (1992 Award Recipient) Uniparental Disomy as a Cause of Genetic Disorders in Children University of Virginia School of Medicine Kathleen E. Walsh, M.D., M.Sc. (2009 Award Recipient) Preventing Errors in the Home Care of Children with Cancer University of Massachusetts Medical School Walshk02@ummhc.org David A. Waltz, M.D. (1994 Award Recipient) Urokinase: A Link to Migration Boston Children's Hospital david.waltz@childrens.harvard.edu Zhu Wang, Ph.D. (2012 Award Recipient) Statistical Methods for Postoperative Morbidity after Cardiac Surgery in Children Connecticut Children's Medical Center zwang@ccmckids.org H. Shaw Warren, M.D. (1988 Award Recipient) Monoclonal Antibodies Directed to Common Epitopes on Bacterial Lipopolysaccharide Massachusetts General Hospital swarren1@partners.org John B. Watkins, M.D. (1978 Award Recipient) Development of Ileal Function and the Regulation of Bile Acid Metabolism in the Neonate Boston Children's Hospital Paula I. Watnick, M.D., Ph.D. (2001 Award Recipient) Regulation of Biofilm Development in a Model Gram‐negative Bacterium Boston Children's Hospital paula.watnick@childrens.harvard.edu Steven J. Weisman, M.D. (1984 Award Recipient) The Functional Role of Mo1 in Granulocyte Activation: Phorbol Ester Activation and Ionic Flux Children's Hospital of Wisconsin sweisman@chw.org Mitchell Weiss, M.D., Ph.D. (1996 Award Recipient) Erythropoiesis in GATA‐1 Gene Disrupted Embryonic Stem Cells and Mice Children's Hospital of Philadelphia weissmi@email.chop.edu Michael J. Whalen, M.D. (2002 Award Recipient) Genetic Inhibition of Posttraumatic Neuronal Cell Death in Immature Mice Massachusetts General Hospital mwhalen@mgh.harvard.edu 44
Alexander S. Whitehead, D.Phil. (1984 and 1985 Award Recipient) Regulation of the Acute Phase Protein Genes Perelman School of Medicine at the University of Pennsylvania aswhitehead@pharm.med.upenn.edu Ruth Whittemore, M.D. (1978 Award Recipient) 26‐29 Year Follow‐up of Blood Pressue in Children Yale School of Medicine John A. Widness, M.D. (1982 and 1983 Award Recipient) Effects of Intrauterine Hypoxemia on Erythropoietin in the Chronically Catheterized Fetal Sheep University of Iowa john‐wideness@uiowa.edu Janey Wiggs, M.D., Ph.D. (1992 Award Recipient) Genetic Linkage Study of Autosomal Dominant Juvenile Glaucoma Massachusetts Eye and Ear Infirmary janey_wiggs@meei.harvard.edu David A. Williams, M.D. (1985 Award Recipient) Retroviral‐mediated Gene Transfer on Gene Sequences Useful for In Vivo Selection of Transduced Hematopoietic Stem Cells Boston Children's Hospital david.williams2@childrens.harvard.edu Harland S. Winter, M.D. (1980 Award Recipient) Immune Function of the Intestinal Macrophage in Children Massachusetts General Hospital hwinter@partners.org Lauren Wise, Sc.D., M.Sc. (2008 Award Recipient) Pre‐Pregnancy Obesity and the Risk of Preterm Birth and Macrosomia: A Prospective Study of African‐American Women Slone Epidemiology Center at Boston University lwise@slone.bu.edu Joanne Wolfe, M.D., M.P.H. (2003 Award Recipient) The Pediatric Quality of Life and Evaluation of Symptoms Technology (PediQUEST) Study: Improving the Care for Children with Advance Cancer Dana‐Farber Cancer Institute joanne_wolfe@dfci.harvard.edu Peter H. Wolff, M.D. (1966 Award Recipient) Studies to Provide a Systematic Description of Mother‐Infant Pairs from Birth through Six Months Judge Baker Children's Center K. I. Wollan, Sc.D. (1955 Award Recipient) Neighborhood Clubs Research Study Derek E. Woods, Ph.D. (1983 Award Recipient) The Molecular Biology of the Human Class III Major Histocompatibility Complex Genes Atto Bioscience, Inc. dwoods@atto.com Ann Chen Wu, M.D., M.P.H. (2009 Award Recipient) Effectiveness of Pharmacogenetic Testing in Asthma Harvard Pilgrim Health Care ann.wu@childrens.harvard.edu 45
Yong Xiong, Ph.D. (2008 Award Recipient) Molecular Dissection of the Fanconi Anemia Pathway of DNA Damage Repair Yale University yong.xiong@yale.edu Haiyan Xu, M.D., Ph.D. (2006 Award Recipient) The Mechanism of MAP Kinase Phosphatase 3 (MKP3) Induced Gluconeogenesis in Obesity and Diabetes Brown University School of Medicine Haiyan_Xu@brown.edu Alfred Yankauer, M.D. (1971 Award Recipient) Pediatric Nurse Practitioner Program Massachusetts General Hospital Martin L. Yarmush, M.D., Ph.D. (1987 Award Recipient) Development of a Hepatocyte‐based Artificial Liver Massachusetts General Hospital myarmush@partners.org Paul M. Yen, M.D. (1993 Award Recipient) Mechanisms of Thyroid Hormone Action in Growth and Development John Hopkins Bayview Medical Center Fay Young, M.D. (1995 Award Recipient) Murine Models of Normal and Abnormal Precursor B‐cell Development University of Rochester Medical Center fay_young@urmc.rochester.edu W.L. Yu, M.D. (1966 Award Recipient) Research to Study the Relationship of Dehydrofolate Reductase with Normal and Leukemic White Blood Cells in Children University of Vermont College of Medicine Marjorie Zakaria, M.D. (1999 Award Recipient) Estrogen Regulation of Gonadotropin‐
Releasing Hormone (GnRH) Gene Expression in Vitro and in Vivo Wyeth Research Vassilis I. Zannis, Ph.D. (1981 Award Recipient) Molecular Cloning of Human Apolipoprotein Genes Boston University School of Medicine vzannis@bu.edu Robert S. Zeiger, M.D., Ph.D. (1975 and 1976 Award Recipient) Histamine Metabolism During Allergy Response Boston Children's Hospital robert.s.zeiger@kp.org Sharon Zemel, M.D. (1994 Award Recipient) Molecular Organization of an Imprinted Domain The Children's Institute mrb@fspkids.org Ronghua ZhuGe, Ph.D. (2003 Award Recipient) Local Ca2+ Signaling and Airway Hyperactivity University of Massachusetts Medical School ronghua.zhuge@umassmed.edu 46
Andrew W. Zimmerman, M.D. (1977 Award Recipient) Zinc Incorporation Into Neural Tissue During Morphogenesis Massachusetts General Hospital Lurie Center for Autism Leonard I. Zon, M.D. (1990 Award Recipient) Regulation of the GATA Binding Transcription Factors in Normal and Abnormal Hematopoiesis in Children (1990 Award Recipient) Regulation of the major erythroid transcription factor (GF‐1) in normal and abnormal hematopoiesis in children Boston Children's Hospital zon@enders.tch.harvard.edu Stephen D. Zucker, M.D. (1996 Award Recipient) Bilirubin Transport and Toxicity in the Neonate University of Cincinnati Medical Center zuckersd@email.uc.edu
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Hood Postdoctoral Research Fellows Jason Randolpha Andrews, M.D. (2013 Fellow) Evaluating Novel Diagnostic Strategies for Enteric Fever in Rural Nepal Massachusetts General Hospital jasonandr@gmail.com Alan H. Beggs, Ph.D. (1992 Fellow) Identification and Characterization of A‐
Actinin Genes in Nemaline Rod Myopathy Boston Children's Hospital beggs@enders.tch.harvard.edu Yee‐Ming Chan, M.D., Ph.D. (2010 Fellow) Using Kisspeptin to Interrogate the Human GnRH Neuron in vivo Boston Children's Hospital yee‐ming.chan@childrens.harvard.edu Robert L. Davis, Ph.D. (1995 Fellow) Cell Differentiation and Tissue Formation in the Frog Tailbud Kalpsys, Inc. rdavis@kalypsys.com Judith C. Fleming, Ph.D. (2000 Fellow) Studies of Thiamine Transporter Gene THTR‐1 Boston Children's Hospital judith.fleming@childrens.harvard.edu David J. Freedman, Ph.D. (2006 Fellow) Neural Mechanisms of Visual Category Learning University of Chicago dfreedman@uchicago.edu Richard E. Frye, M.D., Ph.D. (2003 Fellow) Developmental Phonological Dyslexia: Neural Mechanisms University of Texas, Medical School at Houston Richard.E.Frye@uth.tmc.edu Jeffrey S. Garland, M.D. (1991 Fellow) Do Symptoms or Treatment Modalities for Respiratory Distress Syndrome Increase the Risk of Periventricular‐Ventricular Hemorrhage? Boston Children's Hospital jsgarland@hotmail.com Yan Geng, M.D., Ph.D. (1994 Fellow) The Regulation of Cyclin E in Relation to the Function of pRB Dana‐Farber Cancer Institute yan_geng@dfci.harvard.edu Laura Gibson, M.D. (2001 Fellow) Cytomegalovirus‐Specific CD8+ T Lymphocytes in Infants and Children University of Massachusetts Medical School laura.gibson@umassmed.edu Nadine Gogolla, Ph.D. (2011 Fellow) Multisensory Integration Deficits in Autism: Molecular Mechanisms of Postnatal Development Harvard University ngogolla@mcb.harvard.edu 48
Jesse Heymann Goldberg, M.D., Ph.D. (2009 Fellow) Basal Ganglia‐Thalamic Interactions in Behaving Songbirds During Learning Massachusetts Institute of Technology jesseg1@mit.edu Alon Goren, Ph.D. (2012 Fellow) Chromatin Regulatory Circuits in Mammalian Pre‐implantation Development Broad Institute of MIT and Harvard agoren@broad.mit.edu Lisa M. Guay‐Woodford, M.D. (1990 Fellow) The Molecular Basis of Autosomal Recessive Polycystic Kidney Disease in the cpk Mouse and Man Boston Children's Hospital Timothy J. Hemesath, Ph.D. (1996 Fellow) Microphthalmia, A Myc‐Related Transcription Factor Critical in Development Edel Maria Hyland, Ph.D. (2011 Fellow) Targeting Antibiotic Resistance by Defining the Molecular Basis for Segregation Dependent Plasmid Incompatibility in Bacteria Harvard University ehyland@mcb.harvard.edu Nitya Jain, Ph.D. (2013 Fellow) Understanding Neonatal Immunity: The Influence of Gut Microbial Colonization on Neonatal Adaptive Immunity Massachusetts General Hospital njain@ccib.mgh.harvard.edu Patricia Jensen, Ph.D. (2006 Fellow) Genetic Sublineages of the Mammalian Serotonergic System National Institute of Environmental Health Sciences jensenp3@niehs.nih.gov Isaac S. Kohane, M.D., Ph.D. (1993 Fellow) Knowledge‐Based Automated Detection and Classification of Growth Disorders Boston Children's Hospital zak@chip.org Stella Kourembanas, M.D. (1989 Fellow) Studies on Regulation of Platelet‐Derived Growth Factor Production by Endothelial Cells Boston Children's Hospital Stella.Kourembanas@childrens.harvard.edu Angela M. Leung, M.D. (2009 Fellow) Breast Milk Iodine and Perchlorate Concentrations: Effect on Infant Thyroid Function Boston Medical Center angela.leung@bmc.org Malcolm Logan, Ph.D. (1999 Fellow) An Analysis of Limb‐type Specification and Limb Patterning in the Chick and Mouse MRC National Institute for Medical Research mlogan@nimr.mrc.ac.uk 49
Juliette C. Madan, M.D. (2004 Fellow) Indomethacin Use for Closure of Patent Ductus Arteriosus in VLBW Infants: Association with Necrotizing Enterocolitis and Spontaneous Intestinal Perforation Dartmouth‐Hitchcock Medical Center juliette.madan@hitchcock.org Junhao Mao, Ph.D. (2005 Fellow) The Roles of the Hedgehog Pathway in Adult Muscle Stem Cells and Rhabdomyosarcoma University of Massachusetts Medical School junhao.mao@umassmed.edu Maitreyi Mazumdar, M.D., M.P.H. (2006 Fellow) Health Insurance and Utilization of Services of Children with Epilepsy Boston Children's Hospital maitreyi.mazumdar@childrens.harvard.edu Catherine J. Merrick, Ph.D. (2008 Fellow) Epigenetic Control of Virulence Gene Expression in the Malarial Parasite P. Falciparum Keele University c.merrick@biol.keele.ac.uk Ganeshwaran H. Mochida, M.D., M.M.Sc. (2002 Fellow) Genetic and Clinical Analysis of Autosomal Recessive Microcephaly Massachusetts General Hospital gmochida@partners.org M. Golam Mohi, Ph.D. (2004 Fellow) Role of Shp2 and its Binding Protein Gab2 in Leukemogenesis SUNY Upstate Medical University mohim@upstate.edu
Jaime Murphy, M.D. (2007 Fellow) Circulating Mesenchymal Precursors with Fibrogenic Potential in Asthma Boston Medical Center murphj04@bu.edu George A. O'Toole, Ph.D. (1998 Fellow) Genetic Analyses of Biofilm Formation by Pseudomonas aeruginosa Dartmouth‐Hitchcock Medical Center george.a.otoole@dartmouth.edu Suzanne Paradis, Ph.D. (2003 Fellow) A Role for Ephrin/EphB Signaling in Synapse Formation and Maturation Brandeis University paradis@brandeis.edu Gulcin Pekkurnaz, Ph.D. (2014 Fellow) O‐GlcNAcylation: A Glucose Sensing Pathway for Mitochondria and Energy Homeostasis Boston Children's Hospital gulcin.pekkurnaz@childrens.harvard.edu Miguel N. Rivera, M.D. (2007 Fellow) Characterization of WTX, a Novel Tumor Suppressor Frequently Inactivated in Wilms Tumor Massachusetts General Hospital mnrivera@partners.org Hyun Cheol Roh, Ph.D. (2014 Fellow) Molecular Mechanisms Underlying Beige Adipocyte Dynamics in Response to Thermal Challenges Beth Israel Deaconess Medical Center hroh@bidmc.harvard.edu
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Kathleen A. Ryan, Ph.D. (1992 Fellow) Genetic Analysis of Lipophosphoglycan Biosynthesis in Leishmania Donovani Gerhard Schratt, Ph.D. (2005 Fellow) Investigating the Molecular Mechanism of BDNF‐Regulated Local Dendritic Translation in Mammalian Neurons University of Marburg gerhard.schratt@staff.uni‐marburg.de Anushua Sinha, M.D., M.P.H. (2000 Fellow) Impact of Widespread Antibiotic Use at Delivery on Newborn Outcomes Rutgers University New Jersey Medical School sinhaan1@njms.rutgers.edu Janet S. Soul, M.D., C.M., FRCPC (2001 Fellow) Early Detection of Brain Injury in Posthemorrhagic Hydrocephalus Boston Children's Hospital janet.soul@childrens.harvard.edu Dan Stoleru, M.D., Ph.D. (2008 Fellow) Gene Replacement with Automatic and Fully‐Regulated Insulin Release in Type 1 Diabetes Harvard Medical School stoleru@hms.harvard.edu Ekaterina Toropova, Ph.D. (2012 Fellow) Structural Basis for the Regulation of the Molecular Motor Dynein by Lis1 Harvard University toropova@fas.harvard.edu Tim Van Opijnen, Ph.D. (2010 Fellow) Functional Organization of the Streptococcus Pneumoniae Two Component System Regulatory Network Tufts University School of Medicine tim.vanopijnen@bc.edu Helen J. Wing, M.D., Ph.D. (2002 Fellow) Regulation of the Shigella Virulence Factor IcsP University of Las Vegas, Nevada helen.wing@unlv.edu Phillip D. Zamore, Ph.D. (1997 Fellow) RNA‐Protein Interactions in Translational Regulation in the Drosophila Embryo University of Massachusetts Medical School Phillip.Zamore@umassmed.edu 51