The Scientific Ravi 2014 BIOTECHNOLOGY Peeking into the past (The Harvard University Gazette, December 16, 1999.) CHEMISTRY The figure shows Crick‟s original sketch of the structure of DNA. It was not until 1953 that James Watson and Francis Crick used the results of work by Rosalind Franklin and others to work out the basic structure of the DNA molecule. It was suggested by Watson and Crick that the two strands of the DNA molecule could split apart in order for the nucleotides to be added in front of each strand thus forming complementary strands along each half of the original molecule. (J.D. Watson and F.H.C. Crick. 1953. “A Structure for Deoxyribonucleic Acid. Nature. 171: 737-738.) In 1926, James B. Sumner crystallised urease from Canavalia ensiformis (jackbean), which proved to be a fundamental step in proving that enzymes are proteins. It was the first protein crystal ever obtained and it won Sumner a Nobel Prize in Chemistry in 1946. Ureases (urea amidohydrolases; EC 3.5.1.5) are nickel-dependent enzymes which catalyse the hydrolysis of urea into 1 molecule of carbon dioxide and 2 molecules of ammonia. (J.B. Sumner. 1926. “The Isolation and Crystallisation of the Enzyme Urease.” J. Biol. Chem. 69:435-441.) COMPUTER SCIENCE BOTANY The water lily‟s origin dates back to more than 140 million years. Amborella is the remaining species of this lineage and is now found in only one place in the world – New Caledonia (a small tropical island in a remote corner of the southwest Pacific). It is a shrub with small, not-so-impressive flowers. Thus it is the oldest known flowering plant which has been identified by genes. Government College University, Lahore In 1822, Charles Babbage made a difference engine to compute values of polynomial functions. It was created to calculate a series of values automatically. It became possible to avoid multiplication and division by using the method of finite differences. Some parts of the original prototype are kept in the Museum of the History of Science, Oxford. Had it been completed it would have comprised around 25,000 parts, weighing 13.6 tons and would have been 2.4 m tall. i The Scientific Ravi 2014 (A. Hyman. 1985. Charles Babbage: Pioneer of the Computer. Princeton University Press. p. 115.) ECONOMICS Peeking into the past of induction. It was first observed in 1824 by François Arago though his observations were given a conclusion by Michael Faraday. In conductors with zero resistivity, eddy currents generate heat and electromagnetic forces. The former can be used in induction heating, while the latter can be used to produce a strong braking effect and levitation. On the contrary, eddy currents may have undesirable effects in transformers. The losses may, however, be minimised by lamination. (R. Wangsness. Electromagnetic Fields. 2nd ed. O. 387-388.) Supply-and-demand model is a model for understanding the determination of the price of quantity of a good sold in the market. The explanation works by looking at two different groups – buyers and sellers – and asking how they interact. In other words, it is an economic model of price determination in a market in microeconomics. The four basic laws of this model are: 1. If demand increases and supply remains unchanged, a shortage occurs which leads to a higher equilibrium price. 2. If demand decreases and price remains unchanged, a surplus occurs which leads to a lower equilibrium price. 3. If supply increases and demand remains unchanged, a surplus increases which leads to a lower equilibrium price. 4. If supply decreases and demand remains unchanged, a shortage occurs which leads to a higher equilibrium price. (A. Smith. 1776. “An Inquiry into the Nature and Causes of the Wealth of Nations.”) ELECTRICAL ENGINEERING Eddy currents, also known as Foucault currents, are induced within conductors by a changing magnetic field due to Faraday‟s law Government College University, Lahore ENVIRONMENTAL SCIENCE Silent Spring is a book authored by Rachel Carson and was published on September 27, 1962. Silent Spring presents a view of nature compromised by synthetic pesticides, especially DDT. Once these pesticides entered the biosphere, Carson argued, they not only killed bugs but also made their way up the food chain to threaten bird and fish populations and could eventually sicken children. The book catalogued the environmental impacts of the indiscriminate and uncontrolled spraying of DDT in the USA and questioned the logic of releasing large amounts of chemicals into the environment without fully understanding their effects on ecology or human health. It was suggested that DDT and other pesticides may cause cancer and that their agricultural use was a threat to wildlife, particularly birds. Its publication was one of the signature events in the birth of the environmental movement, and resulted in a ii The Scientific Ravi 2014 Peeking into the past large public outcry that eventually led to DDT being banned in 1972. (A.R. Lovett. 2008. Supercontinent Pangaea Pushed, Not Sucked, Into Place. National Geographic News.) (R. Carson. 1962. Silent Spring. Houghton Mifflin Company, New York and P. Brooks. 1972. The House of Life: Rachel Carson at Work. Houghton Mifflin Company, New York.) MATHEMATICS GEOGRAPHY Al-Khwārizmī (c. 780 – c. 850 A.D.) was a Persian mathematician, geographer and astronomer who is often accredited of establishing the basics of algebra and trigonometry and is thus known as the “Inventor of Algebra”. In his book, AlKhwārizmī gives a wide range of examples regarding the problems in trade, legal inheritance and surveying. The picture given on the left is the original Arabic print manuscript of the Book of Algebra by AlKhwārizmī, while the one on the right shows a page from The Algebra of Al-Khwārizmī by Frederick Rosen in English. Pangaea was a supercontinent that formed approximately 300 million years ago and existed during the late Paleozoic and early Mesozoic eras. Before its breaking apart about 100 million years ago, much of the land mass was in the Southern Hemisphere. It was the first reconstructed supercontinent and was surrounded by a super ocean called Panthalassa. Its existence is evident from the fossils which show the presence of similar and identical species on continents that are now miles apart. To illustrate, the fossils of freshwater reptile Mesosaurus have been found in localised regions of the coasts of West Africa and Brazil. Government College University, Lahore (C.B. Boyer. 1991. “The Arabic Hegemony.” A History of Mathematics. 2nd ed. John Wiley & Sons, Inc.) MICROBIOLOGY iii The Scientific Ravi 2014 There are a few things which space scientists avoid to take outside this plant; one such entity is the microorganisms because they could potentially contaminate other planets other planets the spacecraft visit. However, Tersicoccus phoenicis (Domain: Bacterium; Phylum: Actinobacterium; Class: Actinobacteridae; Order: Actinomycetales; Family: Micrococcaceae) was recently collected independently from the floors of two clean rooms (rooms where spacecrafts are assembled) approximately 2,500 miles apart – one in Centre Spatial Guyanais in Kourou, French Guiana and the other in the Kennedy Space Centre in Florida, USA. Despite frequent sterilisation of clean rooms these microorganism have shown to persist due to tolerance to extreme dryness, pH, temperature and salt concentration. The species name was derived from “tersi”, Latin for clean; “coccus”, Greek for bacterium‟s berry-like appearance; and “phoenicis” to pay homage to Phoenix lander, the spacecraft which was been assembled in the clean room where these bacteria were found. (G. Webster. 2013. “Rare new microbe found in two distinct clean rooms.” NASA.gov. Retrieved: November 6, 2013.) PHYSICS Peeking into the past (A. Salam. 1966. “Magnetic monopole and two photon theories of C-violation.” Physics Letters. 22(5): 683-684.) PSYCHOLOGY The polygraph, which is commonly known as the „lie detector‟, was first invented in 1921, and has been improved and updated with time. Advancement in computer programming has allowed for the development of sophisticated software which allows signals to be displayed on computer screens and helps the examiner in identifying irregularities more efficiently. The device is designed to display certain physiological signs, such as heart rate, blood pressure, respiration and skin conductivity, which in turn allows a specialist (polygraph examiner) to deduce whether the subject is lying or not. We must note that polygraph testing is not an exact science, and there is certainly margin for error in the interpretation of the three metrics. STATISTICS A magnetic photon, as predicted in 1966 by the first Pakistani Nobel Laureate Dr. Abdus Salam, is a hypothetical particle. It is said to be a mixture of even and odd C-parity states and does not couple to leptons (unlike normal photons). It was predicted by certain extensions of electromagnetism in order to include magnetic monopoles. However, there is no experimental evidence for this particle‟s existence as several versions have been ruled out. Government College University, Lahore The term “standard deviation” was first used by Karl Pearson in 1984, initially in his writings and later in his lectures. He replaced the term “mean error” first used for this idea as proposed by Gauss (now, mean error is mathematically distinct from standard deviation). Standard deviation (represented by the Greek letter σ) measures the amount of variation from the average. A high standard deviation indicates that data points are spread out over a large range of values, while a low iv The Scientific Ravi 2014 standard deviation indicates that data points are very close to the mean. (H. Walker. 1931. Studies in the History of the Statistical Method. Baltimore, MD: Williams & Wilkins Co. p. 24-25.) ZOOLOGY Peeking into the past Chironex fleckeri, more commonly known as sea wasp, is a species of box jellyfish found in coastal waters of New Guinea and Australia. It is the most lethal jellyfish in the world. It is the largest of the box jellyfish and its bell grows to approximately the size of a basketball. 15 tentacles trail from each corner of the bell. Since it is virtually transparent, it is impossible to visualise it in its natural habitat which poses a great danger to swimmers. When the jellyfish is swimming, its tentacles contract and are about 15 cm long and 5 mm in diameter. On the contrary, when it is hunting, the tentacles get thinner and become 3 m long. These are day hunters and appear to be „sleeping‟ at night on the ocean floor. (P.J. Fenner. 2000. Chironex fleckeri – the north Australian box-jellyfish.) Government College University, Lahore v