CURRICULUM VITAE
July 2010
Clive Henry Wasserfall
Department of Pathology,
Immunology and Laboratory Medicine,
College of Medicine,
University of Florida.
Box 100275 JHMHC .
(352) 392-0048
e-mail: clive@ufl.edu
Birth:
October 10 1963, Johannesburg, South Africa.
Citizenship:
United States of America.
Family:
Married Ingrid 1985.
Son Dean 1989.
Son Ethan 2003.
Education:
Nat.Dip.Med Tech (South Africa), 1985.
MS. Clinical Chemistry (University of Florida), 1998.
Professional Experience:
2003-Present
Assistant in Pathology, Faculty, Department of
Pathology, Immunology and Laboratory Medicine,
University of Florida College of Medicine. Gainesville,
FL, USA
2001-2003
Science Research Manager, Department of Pathology,
Immunology and Laboratory Medicine, University
of Florida College of Medicine. Gainesville, FL, USA
1994 - 2001
Sr Biological Scientist, Department of Pathology,
Immunology and Laboratory Medicine, University
of Florida College of Medicine. Gainesville, FL, USA.
1992-1993
Acting Head of the Immunology Department, Principal
Medical Technologist, National Center for Occupational
Health. Johannesburg, South Africa.
1992
Fellowship at the South African Institute for Medical
Research advanced Immunology and studies on the
effects of asbestos and mycobacteria tuberculosis on
macrophages. Johannesburg, South Africa.
1989 - 1991
Senior Medical Technologist, Immunology
Department, National Center for Occupational
Health. Johannesburg, South Africa.
1989 - 1993
Part-time Senior Medical Technologist, Serology
Laboratory, Dr.'s Mauff and partners. Johannesburg,
South Africa.
1987 - 1988
National Service: Serology Laboratory, #1 Military
Hospital, Pretoria, South Africa.
1986
Internship, Immunology Department, National Center
for Occupational Health. Johannesburg, South Africa.
1983
Student Medical Technologist, National Center
for Occupational Health. Johannesburg, South Africa.
Honors/Awards:
1999
Productivity award University of Florida.
1996
International Student Society award for
outstanding academic achievement, University
of Florida.
1993
Distinguished Service Award Department of Health,
South Africa.
1992
Behring Diagnostics Award for Best Paper at the
South African Immunology Society Congress,
March 1992; Cape Town, South Africa:
"Asbestos and Cytokines".
Publications:
1. Soderlund N, Rees D, Wasserfall C, Roodt L.: A survey of a small group of
workers exposed to toluene diisocyanate. South African Medical Journal.
83(2):100-103, 1993.
2. Wadee, A.A., Wasserfall, C.H., Sussman, G. Cytokine release in a patient
undergoing maxillo-facial surgery. Southern African Journal of Epidemiology and
Infection. 10(2): 53-55,1995.
3. Lan M, Wasserfall C, Maclaren N, Notkins A.: IA-2, A transmembrane protein of
the protein tyrosine phosphatase family, is a major autoantigen in IDDM.
Proceedings of the National Academy of Science.USA 93(13): 6367-6370, 1996.
4. Ramiya V, Shang XZ, Pharis P, Wasserfall C, Stabler T, Muir A, Schatz D,
Maclaren N.: Antigen based therapies to prevent diabetes in the NOD mouse.
Journal of Autoimmunity 9(3):349-356, 1996.
5. Notkins AL, Lu J, Li Q, VanderVegt FP, Wasserfall C, Maclaren NK., Lan MS.: IA-2
and IA-2b are major autoantigens in IDDM and the precursors of the 40kDa and
37kDa tryptic fragments. Journal of Autoimmunity 9(5):677-682, 1996.
6. Li Q, Borovitskaya AE, DeSilva MG, Wasserfall C, Maclaren NK, Notkins AL, Lan
MS.: Autoantigens in Insulin-Dependent Diabetes Mellitus: Molecular cloning and
characterization of human IA-2b. Proceedings of the Association of American
Physicians 109(4):429-439, 1997.
7. Ramiya VK, Lan MS, Wasserfall CH, Notkins AL, Maclaren NK.: Immunization
therapies in the prevention of Diabetes. Journal of Autoimmunity. 10(3):287-292,
1997.
8. Ramiya VK, Shang XZ, Wasserfall CH, Maclaren NK: Effect of oral and
intravenous insulin and glutamic acid decarboxylase in NOD mice. Autoimmunity
26(3): 139-151, 1997.
9. Ellis TM, Schatz D, Ottendorfer E, Lan M, Wasserfall C, Salisbury PJ, She JX,
Notkins AL, Maclaren NK, Atkinson MA.: The relationship between humoral and
cellular immunity to IA-2 in IDDM. Diabetes. 47(4):566-569, 1998.
10. Rees D, Nelson G, Kielkowski D, Wasserfall C, da Costa A.: Respiratory health
and immunological profile of poultry workers. South African Medical Journal.
88(9):1110-1117, 1998.
11. Mason AL, Lau JY, Hoang N, Qian K, Alexander GJ, Xu L, Guo L, Jacob S,
Regenstein FG, Zimmerman R, Everhart JE, Wasserfall C, Maclaren NK, Perrillo
RP.: Association of diabetes mellitus and chronic hepatitis C virus infection.
Hepatology. 29(2):328-33, 1999.
12. She J-X, Ellis TM, Wilson SB, Wasserfall CH, Marron M, Reimsneider S, Kent
SC, Hafler DA, Neuberg DS, Muir A, Strominger JL, Atkinson MA.: Heterophile
antibodies segregate in families and are associated with protection from type 1
diabetes. Proceedings of the National Academy of Science.USA. 96: 8116-8119,
1999.
13. Litherland SA, Xie XT, Hutson AD, Wasserfall C, Whittaker DS, She J-X, Hofig
A, Dennis MA, Fuller K, Cook R, Schatz D, Moldawer LL, Clare-Salzler MJ.:
Aberrant prostaglandin synthase 2 expression defines an antigen-presenting cell
defect for insulin-dependent diabetes mellitus. Journal of Clinical Investigation.
104(4): 515-523, 1999.
14. Wasserfall C, Atkinson M, Schatz D, She J-X, Ellis TM.: Glutamic Acid
Decarboxylase and IA-2 Autoantibodies in Type 1 Diabetes; Comparing Sample
Substrates for Autoantibody Determinations. Pediatric Diabetes. 1: 10-16, 2000.
15. Flotte T, Agarwal A, Wang J, Song S, Fenjves ES, Inverardi L, Chesnut K, Afione
S, Loiler S, Wasserfall C, Kapturczak M, Ellis T, Nick H and Atkinson M: Efficient
Ex Vivo Transduction of Pancreatic Islet Cells with Recombinant AdenoAssociated Virus Vectors. Diabetes 50(3):515-520, 2001.
16. Goudy K, Song S, Wasserfall C, Zhang C, Kapturczak M, Muir A, Powers M,
Scott-Jorgensen M, Campbell-Thompson M, Crawford JM, Ellis TM, Flotte TR,
Atkinson MA: Adeno-associated virus vector mediated Interleukin-10 gene
delivery prevents type 1 diabetes in NOD mice. . Proceedings of the National
Academy of Science.USA 98(24):13913-13918, 2001.
17. Zhang, Y.C.; Molano, R.D.; Pileggi, A.; Powers, M.; Cross J.; Wasserfall, C.:
Scott-Jorgensen M.; Campbell-Thompson M.; Crawford JM.; Flotte, T.; Ellis,
T.M.; Ricordi, C.; Atkinson, M.A.; Inverardi, L.: Adeno-Associated Virus
Transduction of Islets with Interleukin-4 results in Impaired Metabolic Function in
Syngeneic Marginal Mass Islet Transplantation. Transplantation. 74(8):11841186, 2002.
18. Cushman J, Lo J, Huang Z, Wasserfall C, Petitto JM.: Neurobehavioral changes
resulting from recombinase activation gene 1 deletion. Clinical and Diagnostic
Laboratory Immunology. 10(1) 13-18, 2003.
19. Zhang, Y.C.; Pileggi, A.; Agarwal, A.; Molano, R.D.; Powers, M.; Brusko, T.;
Wasserfall, C.; Goudy, K.; Zahr, E.; Poggioli, R.; Scott Jorgensen, M.; CampbellThompson, M.; Crawford, J.M.; Nick, H.; Flotte, T.; Ellis, T.M.; Ricordi, C.;
Inverardi, L.; Atkinson, M.A.: Adeno-Associated Virus Mediated Interleukin-10
Gene Therapy Inhibits Autoimmune Diabetes Recurrence in Syngeneic Islet
Transplanted NOD Mice. Diabetes. 52: 708-716, 2003.
20. Litherland, S.A., J.-X. She, D. Schatz, K. Fuller, A.D. Hutson, Y. Li, K. M. Grebe,
D. S. Whittaker, K. Bahjat, D. Hopkins, Q. Fang, C. Wasserfall, R. Cook, M.A.
Dennis, S. Crockett, J. Sleasman, J. Kocher, A. Muir, J. Silverstein, M. Atkinson,
and M. J. Clare-Salzler. Aberrant Monocyte Prostaglandin Synthase 2 (PGS2) in
Type 1 Diabetes Before & After Disease Onset. Pediatric Diabetes. 4: 10-18,
2003.
21. Yu L, Eisenbarth G, Bonifacio E, Thomas J, Atkinson M, Wasserfall C.: The
Second Murine Autoantibody Workshop: Remarkable Concordance of
Radiobinding Assays to Identify Insulin Autoantibodies in Non-Obese Diabetic
Mice. Annals of the New York Academy of Science 1005: 1-12, 2003.
22. Goudy K, Burkhardt B, Wasserfall C, Song S, Campbell-Thomson M, Brusko T,
Powers M, Clare-Salzler M, Sobel E, Ellis T, Flotte T, Atkinson M.: Systemic
Over Expression of IL-10 Induces CD4+CD25+ Cell Populations in Vivo and
Ameliorates Type 1 Diabetes in Nod Mice. Journal of Immunology. 171: 2270–
2278, 2003.
23. Song, S.; Goudy, K.; Campbell-Thompson, M.; Wasserfall, C.; Scott-Jorgensen,
M.; Wang, J.; Tang, Q.; Ellis, T.; Crawford, J.M.; Atkinson, M.A.; Flotte, T.R.:
Recombinant Adeno-Associated Virus (rAAV2) Mediated Alpha-1 Antitrypsin
Gene Therapy Prevents Type 1 Diabetes in NOD Mice. Gene Therapy. 11(2):
181-186, 2004.
24. Zhang, Y.C.; Powers, M.; Wasserfall, C.; Brusko, T.; Sihong Song, S.; Flotte,
T.R.; Snyder, R.; Potter, M.; Scott-Jorgensen, M.; Campbell-Thompson, M.;
Crawford, J.M.; Ellis, T.M.; Atkinson, M.A.: Immunity to Adeno-Associated Virus
Delivered Transgenes Imparted by Genetic Predisposition to Autoimmunity.
Gene Therapy. 11(3): 233-240, 2004.
25. Morales, A.; Wasserfall, C.; Brusko T.; Carter C.; Schatz D.; Silverstein, J.; Ellis
T.; Atkinson, M.: Adiponectin and Leptin Concentrations May Aid in
Discriminating Disease Forms in Children and Adolescents with Type 1 and Type
2 Diabetes. Diabetes Care. 27(8): 2010-2014, 2004.
26. Kapturczak MH †, Wasserfall C †, Brusko T, Campbell-Thompson M, Ellis TM,
Atkinson MA, and Agarwal A: Heme oxygenase-1 modulates early inflammatory
responses: Evidence from the heme oxygenase-1 deficient mouse. American
Journal of Pathology. 165(3):1045-1053, 2004. †Contributed equally to this work.
27. Haller MJ, Samyn M, Nichols WW, Brusko T, Wasserfall C, Schwartz RF,
Atkinson M, Shuster JJ, Pierce GL, Silverstein JH: Radial Artery Tonometry
Demonstrates Arterial Stiffness in Children with Type 1 Diabetes. Diabetes Care.
27(12): 2911-2917, 2004.
28. Serreze DV, Wasserfall C, Ottendorfer EW, Stalvey M, Pierce MA, Gaunnt C,
O’Donnell B, Flanagan JB, Campbell-Thompson M, Ellis TM,. Atkinson
MA:Diabetes acceleration or prevention by Coxsackie virus infection; critical
requirements for both interleukin-4 and interferon gamma. Journal of Virology.
79(2): 1045-1052, 2005.
30. .Greenbaum CJ, Eisenbarth G, Atkinson M, Yu L, Babu S, Schatz D, Zeidler A,
Orban T, Wasserfall C, Cuthbertson D, Krischer J, and the DPT-1 study group.:
High Frequency of Abnormal Glucose Tolerance in DQa1*0102/DQb1*0602
Relatives of Patients with Type 1 Diabetes. Diabetologia. 48(1): 68-74, 2005.
31. Ramirez-Montealegre D, Chattopadhya S, Curran TM, Wasserfall, C, Pritchard
L, Schatz D, Petitto J, Hopkins D, She JX, Rothberg PG, Atkinson M, Pearce DA:
Autoimmunity to glutamic acid decarboxylase in the neurodegenerative disorder
Batten disease. Neurology. 64: 743-745, 2005.
32. Cresawn KO, Fraites TJ, Wasserfall C, Atkinson MA, Lewis M, Porvasnik S,
Mah C, Lui C, Byrne BJ: AAV5-Mediated Cross-Correction of Glycogen Storage
Disease Type II: Effects of Inhibitory Antibody Formation and immunomodulation.
Human Gene Therapy. 16(1): 68-80, 2005.
33. Beck, RD Wasserfall C, Ha GK, Cushman JD, Huang Z, Atkinson M, Petitto JM.:
Changes in hippocampal IL-15, related cytokines and neurogenesis in IL-2
Deficient mice. Brain Research. 1041(2): 223-230, 2005.
34. Brusko T.; Wasserfall C.; Clare-Salzler M.; Schatz D.; Atkinson M.: Functional
defects and the influence of age on the frequency of CD4+CD25+ T cells in type
1 diabetes. Diabetes. 54(5): 1407-14, 2005.
35. Brusko TM, Wasserfall CH, Agarwal A, Kapturczak, MH, Atkinson MA: An
Integral Role for Heme Oxygenase-1 and Carbon Monoxide in Maintaining
Peripheral Tolerance by CD4+CD25+ Regulatory T Cells. Journal of Immunology
174(9): 5181-6, 2005.
36. Chen, S.; Kapturczak, M.H.; Wasserfall, C.; Glushakova, O.Y.l CampbellThompson, M.; Deshane, J.S.; Joseph, R.; Hauswirth, W.W.; Madsen, K.M.;
Croker, B.P.; Berns, K.I.; Atkinson, M.A.; Flotte, T.R.; Tisher, C.C.; Agarwal, A.:
Interleukin-10 attenuates neointimal proliferation and inflammation in aortic
allografts via a heme oxygenase dependent pathway. Proceedings of The
National Academy of Sciences, USA 102(20): 7251-7256, 2005.
37. Lee CH, Reifsnyder PC, Naggert JK, Wasserfall C, Atkinson MA, Chen J, Leiter
EH: Novel Leptin Receptor Mutation in NOD/LtJ Mice Suppresses Type 1
Diabetes Progression. I. Pathophysiologic analysis. Diabetes, 54(9): 2525-2532,
2005.
38. Zhang YC.; Pileggi A.; Molano RD.; Wasserfall C.; Campbell-Thompson M.;
Ricordi C.; Atkinson MA.; Inverardi L.: Systemic Overexpression of Interleukin-10
Fails to Protect Allogeneic Islet Transplants in Mice. Transplantation 80(4): 530533, 2005.
39. Burkhardt BR, Parker MJ, Zhang YC, Song S, Wasserfall CH, Atkinson
MA:Glucose transporter-2 (GLUT2) promoter mediated transgenic insulin
production reduces hyperglycemia in diabetic mice. FEBS Letters. 579(25):57595764, 2005.
40. Lee CH, ChenYG, Chen J, Reifsnyder PC, Serreze DV, Clare-Salzler M,
Rodriguez M, Wasserfall C, Atkinson MA, Leiter EH: Novel Leptin Receptor
Mutation in NOD/LtJ Mice Suppresses Type 1 Diabetes Progression. II.
Immunologic analysis. Diabetes 55(1):171-178 ,2006.
41. Muller C, Braag S, Herlihy JD, Wasserfall C, Chesrown SE, Nick HS, Atkinson
MA, Flotte TR: Enhanced IgE allergic response to Aspergillus fumigatus in
CFTR-/- mice. Laboratory Investigation 86(2):130-140, 2006.
42. Burkhardt BR, Greene SR, White P, Wong RK, Brestelli JE, Yang J, Robert CE,
Brusko T, Wasserfall CH, Kaestner KH, Wu J, Atkinson MA, Gao Z, Wolf BA.:
PANDER-induced cell-death genetic networks in islets reveal central role for
caspase-3 and cyclin-dependent kinase inhibitor 1A (p21). Gene 369: 134-141,
2006.
43. Wasserfall C, Atkinson MA: Autoantibody markers for the diagnosis and
prediction of type 1 diabetes. Autoimmunity Reviews 5(6): 424-428, 2006.
44. Araya CE, Wasserfall CH, Brusko TM, Mu W, Segal MS, Johnson RJ, Garin EH:
A Case of Unfulfilled Expectations. Cytokines in Idiopathic Minimal Lesion
Nephrotic Syndrome. Pediatric Nephrology 21(5): 603-610, 2006.
45. Chen S, Wasserfall C, Kapturczak M, Atkinson M, Agarwal A: Freeze-thaw
increases adeno-associated virus transduction of cells. American Journal of
Physiology- Cell Physiology 291(2): C386-C392, 2006.
46. Lu Y, Tang M, Wasserfall C, Kou Z, Campbell-Thompson M, Gardemann T,
Atkinson M, Song: Alpha 1 antitrypsin gene therapy modulates cellular immunity
and prevents type 1 diabetes. Gene Therapy 17(6): 625-634, 2006.
47. Stalvey MS, Schatz D, Wasserfall C, Muller C, Campbell-Thompson M,
Theriaque DW, Flotte TR, Atkinson MA: Cystic Fibrosis Transmembrane
Conductance Regulator (CFTR) Mutation Exacerbates Islet Cell Dysfunction
Following Beta Cell Injury. Diabetes 55(7): 1939-1945, 2006.
48. Brusko T, Wasserfall C, McGrail K, Schatz R, Viener HL, Schatz D, Haller M,
Rockell J, Gottlieb P, Clare-Salzler M, Atkinson M: No Alterations in the
+
Frequency of FOXP3 Regulatory T Cells in Type 1 Diabetes. Diabetes 56(3):
604-612, 2007.
49. Chen, B; Kapturczak, MH; Joseph, R; George, JF; Campbell-Thompson, M;
Wasserfall, CH; Atkinson, MA; Tisher, CC; Flotte, TR; Agarwal, A; Chen S:
Adeno-Associated Virus Vector-Mediated Interleukin-10 Prolongs Allograft
Survival in a Rat Kidney Transplantation Model. American Journal of
Transplantation 7(5): 1112-1120, 2007.
50. Zhang, B; Lu, Y; Campbell-Thompson, M; Spencer, T; Wasserfall, C; Atkinson,
M; Song, S: Alpha 1 Antitrypsin Protects -Cells from Apoptosis. Diabetes 56:
1316-1323, 2007.
51. King M, Pearson T, Shultz LD, Leif JH, Bottino R, Trucco M, Atkinson M,
Wasserfall C, Herold KC, Mordes JP, Rossini AA, Greiner DL. Development of
New-Generation Hu-Pbmc-Nod/Scid Mice to Study Human Islet Allo-Reactivity.
Annals of the New York Academy of Science. 1103: 90-93, 2007.
52. Tsai, YY; Oca-Cossio, J; Agering, K; Simpson, NE; Atkinson, MA; Wasserfall,
CH; Constantinidis, I; Sigmund, W.: Novel synthesis of cerium oxide
nanoparticles for free radical scavenging. Nanomedicine. 2(3): 325-332, 2007.
53. Montoya CJ, Pollard D, Kumari K, Wasserfall C, Rugeles MT, Mulder CB,
Atkinson MA, Landay AL, Wilson SB: Characterization of human iNKT subsets in
health and disease using a novel iNKT cell-clonotypic monoclonal antibody, 6B11
Immunology. 122(1): 1-14, 2007.
54. So PW, Yu WS, Kuo YT, Wasserfall C, Goldstone AP, Bell JD, Frost G.: Impact
of resistant starch on body fat patterning and central appetite regulation. PLoS
ONE 12;2(12):e1309, 2007.
55. Caicedo RA, Li N, des Robert C, Scumpia PO, Hubsher CP, Wasserfall CH,
Schatz DA, Atkinson MA, Neu J: Neonatal Formula Feeding Leads to
Immunological Alterations in an Animal Model of Type 1 Diabetes. Pediatric
Research. 63(3): 303-307, 2008.
56. Simon G, Parker M, Ramiya V, Wasserfall C, Huang Y, Bresson D, Schwartz
RF, Campbell-Thompson M, Tenace L, Brusko T, Xue S, Scaria A, Lukason M,
Eisenbeis S, Williams J, Clare-Salzler M, Schatz D, Kaplan B, Von Herrath M,
Womer K, Atkinson MA: Murine anti-thymocyte globulin therapy alters disease
progression in NOD mice by a time dependent induction of immunoregulation
Diabetes. 57(2): 405-414, 2008
57. King M, Pearson T, Shultz LD, Leif J, Bottino R, Trucco M, Atkinson MA,
Wasserfall C, Herold KC, Woodland RT, Schmidt MR, Woda BA, Thompson MJ,
Rossini AA, Greiner DL.: A new Hu-PBL model for the study of human islet
alloreactivity based on NOD-scid mice bearing a targeted mutation in the IL-2
receptor gamma chain gene. Clinical Immunology. 126(3): 303-314, 2008.
58. Haller MJ, Viener HL, Wasserfall C, Brusko T, Atkinson MA, Schatz DA.:
Autologous Umbilical Cord Blood Infusion for Type 1 Diabetes. Experimental
Hematology. 36(6):710-715, 2008.
59. George JF, Braun A, Brusko TM, Joseph R, Bolisetty S, Wasserfall CH,
Atkinson MA, Agarwal A, Kapturczak MH.: Suppression by CD4+CD25+
regulatory T cells is dependent on expression of heme oxygenase-1 in antigen
presenting cells. American Journal of Pathology. 173(1):154-160, 2008.
60. Pileggi A, Molano RD, Song S, Zahr E, Sanjose S, Villate S, Wasserfall C,
Ricordi C, Atkinson MA, Inverardi L.: Alpha-1 antitrypsin treatment of
spontaneously diabetic nonobese diabetic mice receiving islet allografts.
Transplant Proceedings. 40(2):457-458, 2008.
61. Molano RD, Pileggi A, Song S, Zahr E, San Jose S, Molina J, Fort A, Wasserfall
C, Ricordi C, Atkinson MA, Inverardi L.: Prolonged islet allograft survival by
alpha-1 antitrypsin: the role of humoral immunity. Transplant Proceedings.
40(2):455-456, 2008.
62. Stalvey MS, Brusko TM, Mueller C, Wasserfall CH, Schatz DA, Atkinson MA,
Flotte TR: CFTR Mutations Impart Elevated Immune Reactivity in a Murine Model
of Cystic Fibrosis Related Diabetes. Cytokine. 44(1):154-159, 2008.
63. Lu Y, Parker M, Pileggi A, Zhang B, Choi YK, Molano RD, Wasserfall C, Ricordi
C, Inverardi L, Brantly M, Schatz D, Atkinson M, Song S.: Human Alpha 1Antitrypsin Therapy Induces Fatal Anaphylaxis in NOD Mice. Clinical and
Experimental Immunology. 154(1):15-21, 2008.
64. Suarez-Pinzon WL, Power RF, Yan Y, Wasserfall C, Atkinson M, Rabinovitch A:
Combination Therapy with Glucagon-Like Peptide-1 and Gastrin Restores
Normoglycemia in Diabetic NOD Mice. Diabetes. 57(12): 3281-3288, 2008.
65. Xue S, Wasserfall CH, Parker M, Brusko TM, McGrail S, McGrail K, Moore M,
Campbell-Thompson M, Schatz DA, Atkinson MA, Haller MJ.: Exendin-4 therapy
in NOD mice with new-onset diabetes increases regulatory T cell frequency.
Annals of the New York Academy of Science. 1150: 152-156, 2008.
66. Campbell-Thompson M, Dixon LR, Wasserfall C, Monroe M, McGuigan JM,
Schatz D, Crawford JM, Atkinson MA: Pancreatic adenocarcinoma patients with
localised chronic severe pancreatitis show an increased number of single beta
cells, without alterations in fractional insulin area. Diabetologia. 52(2): 262-270,
2009.
67. Garin EH, Diaz LN, Mu W, Wasserfall C, Araya C, Segal M, Johnson RJ: Urinary
CD80 Excretion Increases in Idiopathic Minimal-Change Disease. Journal
American Society of Nephrology. 20(2): 260-266, 2009.
68. Pashuck TD, Franz SE, Altman MK, Wasserfall CH, Atkinson MA, Wronski TJ,
Flotte TR, Stalvey MS: Murine Model for Cystic Fibrosis Bone Disease
Demonstrates Osteopenia and Sex-Related Differences in Bone Formation.
Pediatric Research. 65(3): 311-316, 2009.
69. Huang Y, Parker M, Xia C, Peng R, Wasserfall C, Clarke T, Wu L, Chowdhry T,
Campbell-Thompson M, Williams J, Clare-Salzler M, Atkinson MA, Womer KL:
Rabbit polyclonal mouse antithymocyte globulin administration alters dendritic
cell profile and function in NOD mice to suppress diabetogenic responses.
Journal of Immunology 182(8):4608-4615, 2009.
70. Xue S, Wasserfall C, Parker M, McGrail S, McGrail K, Campbell-Thompson M,
Schatz DA, Atkinson MA, Haller MJ.: Exendin-4 treatment of nonobese diabetic
mice increases beta-cell proliferation and fractional insulin reactive area. (In
press Journal of Diabetes Complications). 2009.
71. Roesch LF, Lorca GL, Casella G, Giongo A, Naranjo A, Pionzio AM, Li N, Mai V,
Wasserfall CH, Schatz D, Atkinson MA, Neu J, Triplett EW.: Cultureindependent identification of gut bacteria correlated with the onset of diabetes in
a rat model. International Society of Microbial Ecology Journal. 3(5):536-548,
2009.
72. Roesch LF, Casella G, Simell O, Krischer J, Wasserfall CH, Schatz D, Atkinson
MA, Neu J, Triplett EW: Influence of fecal sample storage on bacterial community
diversity. Open Microbiology Journal. 3:40-46, 2009.
73. Araya C, Diaz L, Wasserfall C, Atkinson M, Mu W, Johnson R, Garin E: T
regulatory cell function in idiopathic minimal lesion nephrotic syndrome. Pediatric
Nephrology. 24(9):1691-1698, 2009.
74. Parker MJ, Xue S, Alexander JJ, Wasserfall CH, Campbell-Thompson ML,
Battaglia M, Gregori S, Mathews CE, Song S, Troutt M, Eisenbeis S, Williams J,
Schatz DA, Haller MJ, Atkinson MA: Immune Depletion with Cellular Mobilization
Imparts Immunoregulation and Reverses Autoimmune Diabetes in NOD Mice.
Diabetes. 58(10):2277-2284, 2009.
75. Bierschenk L, Alexander J, Wasserfall C, Haller M, Schatz D, Atkinson M
Vitamin D Levels in Subjects With and Without Type 1 Diabetes Residing in a
Solar Rich Environment. Diabetes Care. 32(11):1977-1979, 2009.
76. Haller MJ, Wasserfall CH, McGrail KM, Cintron M, Brusko TM, Wingard JR,
Kelly SS, Shuster JJ, Atkinson MA, Schatz DA: Autologous umbilical cord blood
transfusion in very young children with type 1 diabetes. Diabetes Care.
32(11):2041-2046, 2009.
77. Wasserfall CH, Herzog RW: Gene therapy approaches to induce tolerance in
autoimmunity by reshaping the immune system. Current Opinion in
Investigational Drugs. 10(11):1143-1150, 2009.
78. Brusko TM, Wasserfall CH, Hulme MA, Cabrera R, Schatz D, Atkinson MA.:
Influence of membrane CD25 stability on T lymphocyte activity: implications for
immunoregulation. PLoS One. 4(11):e7980, 2009.
79. Cabrera R, Ararat M, Cao M, Xu Y, Wasserfall C, Atkinson MA, Liu C, Nelson
DR. Hepatocellular Carcinoma Immunopathogenesis: Clinical Evidence for
Global T Cell Defects and an Immunomodulatory Role for Soluble CD25
(sCD25). Digestive Diseases and Sciences. 55(2):484-495, 2010.
80. Gianani R, Campbell-Thompson M, Sarkar SA, Wasserfall C, Pugliese A, Solis
JM, Kent SC, Hering BJ, West E, Steck A, Bonner-Weir S, Atkinson MA,
Coppieters K, von Herrath M, Eisenbarth GS.: Dimorphic histopathology of longstanding childhood-onset diabetes. Diabetologia. 53(4): 690-698, 2010.
81. Kuo YT, So PW, Parkinson JR, Yu WS, Hankir M, Herlihy AH, Goldstone AP,
Frost GS, Wasserfall C, Bell JD.: The combined effects on neuronal activation
and blood-brain barrier permeability of time and n-3 polyunsaturated fatty acids in
mice, as measured in vivo using MEMRI. Neuroimage. 50(4):1384-1391, 2010.
82. Valladares R, Sankar D, Li N, Williams E, Lai KK, Abdelgeliel AS, Gonzalez CF,
Wasserfall CH, Larkin J, Schatz D, Atkinson MA, Triplett EW, Neu J, Lorca GL.
Lactobacillus johnsonii N6.2 mitigates the development of type 1 diabetes in BBDP rats. PLoS One. 5(5):e10507, 2010.
83. Ma H, Lu Y, Li H, Campbell-Thompson M, Parker M, Wasserfall C, Haller M,
Brantly M, Schatz D, Atkinson M, Song S.: Intradermal alpha1-antitrypsin therapy
avoids fatal anaphylaxis, prevents type 1 diabetes and reverses hyperglycaemia
in the NOD mouse model of the disease. Diabetologia. (epub ahead of print.)
2010.
84. Giongo A, Gano KA, Crabb DB, Mukherjee N, Novelo LL, Casella G, Drew JC,
Ilonen J, Knip M, Hyöty H, Veijola R, Simell T, Simell O, Neu J, Wasserfall CH,
Schatz D, Atkinson MA, Triplett EW.: Toward defining the autoimmune
microbiome for type 1 diabetes. International Society of Microbial Ecology
Journal. 2010 [Epub ahead of print].
Letters/Commentaries/Editorial material
1. Honeyman M, Wasserfall C, Nerup J, Rossini A. Prediction and prevention of
IDDM. Diabetologia. 1997 Suppl 3:B58-61
2. Schwartz RF, Neu J, Schatz D, Atkinson MA, Wasserfall C. Comment on:
Brugman S et al. (2006) Antibiotic treatment partially protects against type 1
diabetes in the Bio-Breeding diabetes-prone rat. Is the gut flora involved in the
development of type 1 diabetes?. Diabetologia. 2007 50(1):220-221
3. Wasserfall C, Atkinson MA. Taking a daily vitamin to prevent type 1 diabetes?
Diabetes. 2009 58(1):24-25
Book Chapters / Monographs:
1. Bigazzi PE, Burek CL, Rose NR, Zakarija M, Mckenzie JM, Wasserfall C,
Maclaren N. Endocrinopathies: In Rose NR, De Macario EC, Folds JD. Eds.,
Manual of Clinical and Laboratory Immunology. American Society of Microbiology.
April 1997.
2. Stalvey M, Atkinson MA, Wasserfall C: Lessons from Attempts to Prevent Type 1
Diabetes - Potential Implications for Type 2 Diabetes. Medicographica 2005.
Journal Reviewer:
Diabetes,
Pediatric Diabetes,
Journal of Clinical Endocrinology and Metabolism
Journal of Autoimmunity,
Diabetologia,
Journal of Pediatric Endocrinology and Metabolism,
Diabetes Care,
Diabetes/Metabolism Research and Reviews
Journal of Immunology,
Clinical Immunology,
Abstracts:
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Wasserfall,C Pitt, MLM. Silicosis: An Immunological study. Society of Medical
Laboratory Technologists of South Africa, Cape Town, South Africa September
1986.
Wasserfall,C Wadee,A. Asbestos and cytokines. South African Immunology Society
Congress, Cape Town, South Africa March 1992.
Da Costa,A Wasserfall,C Wadee,A. Evaluation of ECP levels in a TDI exposed
workforce. South African Immunology Society Congress, Cape Town, South Africa
March 1992.
Roodt,L Wasserfall,C Nelson,G Rees,D. Immunological profile and respiratory
symptoms in poultry workers. ALLSA/IAACI Congress, Johannesburg, South Africa
Oct 1994.
Wasserfall,C Schatz,D Mehta,H Vold,B Krischer,J Atkinson,M Maclaren, N.
Glutamic acid decarboxylase autoantibodies (GAD65A) measured by ELISA
powerfully predict impending IDD in the general population. 55th Annual
Meeting/ADA Scientific Sessions, Atlanta, GA USA June 10-13, 1995.
Ramiya,V Muir,A Wasserfall,C Schott,M Schatz,D Maclaren,N. Protection from
Diabetes by prophylactic oral insulin and GAD feedings in NOD mice. 55th Annual
Meeting/ADA Scientific Sessions, Atlanta, GA USA June 10-13, 1995.
Varga-House,D Nakamura,M Wasserfall,C Maclaren,N Winter,W. Further evidence
that ADM is not an autoimmune disease: studies of GADab in atypical
diabetes(ADM). American Assoc for Clinical Chemistry, Anaheim,CA, USA July 1520, 1995.
Ramiya,V Muir,A Wasserfall,C Shang,XZ, Schatz,D Maclaren,N. Autoantigenspecific immunotherapies in the prevention of diabetes in NOD mice. IDW Meeting,
Rome, Italy Oct 29-Nov 6, 1995.
Wasserfall,C Schatz,D, Krischer,J Mehta,H, Vold,B, Lan,M Notkins,A Maclaren,N.
Autoantibodies to ICA, IAA, GAD65 and IA-2 to predict IDD in relatives and
schoolchildren. IDW Meeting, Rome, Italy Oct 29-Nov 6, 1995.
Bhisitkul,DM Vinik,AI Holmes SJ BrandisIV,RB Owen,WC Wasserfall,CH
Maclaren,NK. Insulin autoantibodies (IAA) in children with sickle cell disease (SCD)
predict growth delay and disease severity. American Pediatric Society, Washington,
D.C., USA May 1996.
Schatz,D Krischer,J Wasserfall,C Lan,M Notkins,A Muir,A Maclaren,N.
ICA,GAD65A,IAA and IA-2A to screen for IDD in schoolchildren and unaffected
relatives. ADA Scientific Sessions, San Francisco, CA USA June 8-11. 1996.
Huang,W House,D Nakamura,M Wasserfall,C Lan,M She,JX Winter,W. Molecular
HLA-DQB1 typing and IA-2A determinations in atypical diabetes mellitus (ADM).
ADA Scientific Sessions, San Francisco, CA USA June 8-11, 1996.
Ramiya,V Wasserfall,C Lan,M Notkins,A Muir,A Schatz,D Maclaren,N.:
Immunization therapies in Diabetes Prevention. IDW meeting, Canberra, Australia 812 December 1996.
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Lan,M.S Li,Q Borovitskaya,A.E DeSilva,M.G Wasserfall,C Maclaren,N.K and
Notkins,A.L: Molecular cloning and characterization of human IA-2b. IDW meeting,
Canberra, Australia 8-12 December 1996.
Wasserfall,C Schatz,D Krischer,J Lan,M Notkins,A Maclaren,N: Multiple
autoantibodies define risk of IDD in a low risk general population of normal US
schoolchildren. IDW meeting, Canberra, Australia 8-12 December 1996.
Ellis,TM Schatz,D Ottendorfer,E Wasserfall,C Maclaren,NK Atkinson,MA: Cellular
immune reactivities against proinsulin in insulin dependent diabetes. IDF congress,
Helsinki, Finland 20-25 July 1997. Diabetologia 40: Suppl 1, A88, 1997.
Ellis,TM Schatz,D Lan,MS Ottendorfer,E Wasserfall,C Notkins,AL Maclaren,NK
Atkinson,MA: Relationship between humoral and cellular immunity to IA-2 in insulin
dependent diabetes. IDF congress, Helsinki, Finland 20-25 July 1997. Diabetologia
40: Suppl 1,A84, 1997.
Wasserfall, C., Wilson, B., Kent, S., Hafler,D., Strominger,J., She, JX., Schatz, D.,
Atkinson, M., Ellis,T.: Increased serum interleukin-4 (IL-4) in IDDM: Evidence for
inheritance in multiplex families of a trait associated with protection from disease.
ADA scientific sessions. Chicago, IL USA 13-16 June 1998. Diabetes 47 Suppl 1
A217,1998
Ellis, TM, Wilson, BS, Wasserfall, C., Kent, S., Strominger, J., Hafler, D., Atkinson,
MA: Potential heterophilic antibodies as a confounding variable to measurement of
serum interleukin-4 (IL-4). ADA scientific sessions. San Diego, CA, USA 19- 22
June 1999. Diabetes 48 Suppl 1 A210, 1999.
Aptsiauri N, Ellis T, Wasserfall C, Guy J, Hekenlively J, Atkinson M, Jodoin E.
Glutamic Acid Decarboxylase ( GAD ) autoantibodies in patients with autoimmune
retinopathies: CAR-Syndrome, diabetic retinopathy and retinitis pigmentosa ( RP )
with cystoid macular edema ( CME ). 4th IDS meeting Fiuggi, Italy November 1215 1999.
Wasserfall C, Atkinson M, Jodoin E, Schatz D, She J-X, Ellis T. Glutamic Acid
Decarboxylase ( GAD ) and IA-2 autoantibodies in type 1 diabetes; comparing
sample substrates for autoantibody determination. 4 th IDS meeting Fiuggi, Italy
November 12-15 1999.
Falcone M, Wasserfall C, Jodoin E, Schatz D, Ellis T, Atkinson M. : Cytokine
elaboration from peripheral blood mononuclear cells of persons participating in the
Diabetes Prevention Trial-Type 1 (DPT-1). 4th IDS meeting Fiuggi, Italy November
12-15 1999.
Atkinson M, Bonifacio E, Bosi E, Ellis T, Eisenbarth G, Hannon H, Henderson O,
Jackson R, Lernmark A, Lou D, Mei J, Mitchell M, Orban T, Vogt R, Wasserfall
C, Yu l. Dried blood spots as a substrate for type 1 diabetes autoantibody
detection. 4th IDS meeting Fiuggi, Italy November 12-15 1999.
Qin H-Y, Mahon JL, Chaturvedi P, Ellis TM, Wasserfall CH, Atkinson MA, Elliot JF,
Singh B. Glucose regulated protein (GRP94/HSP90alpha) autoantibodies correlate
with anti GAD-65 and ICA in Type-1 diabetes 4th IDS meeting Fiuggi, Italy
November 12-15 1999.
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Henderson,LO Atkinson,M Bingley,P Bonifacio,E Bossi,E Ellis,T Eisenbarth,G
Hagopian,W Hannon,WH Jackson,R Lernmark,A Lou,D Mei,J Orban,T Smith,SJ
Vogt,RJ Wasserfall,C Williams,AJK Yu,L and DBSTAR GROUP. Dried BloodSpots as a Matrix for Type-1 Diabetes Autoantibody Detection. 60th Annual
Meeting/ADA Scientific Sessions, San Antonio, TX June 9-13, 2000.
Litherland, S.A., T.X. Xie, D.S. Whittaker, K. Bahjat, K.M. Grebe, L. Selvaraj, C.
Wasserfall, A. B. Peck, L.L. Moldawer, and M. J. Clare-Salzler.: Type 1 Diabetic
Monocyte Prostaglandin Synthase 2 Activity Impairs T cell Activation Induced Cell
Death by Suppressing IL-2 Signaling. FASEB/Experimental Biology/AAI Annual
Meeting, March 2001, Orlando, Florida
Morales A, Anderson J, Jodoin E, Novak D, Schatz D, Atkinson M, Ellis T,
Wasserfall C: Age related association of autoantibodies to tissue
transglutaminase in a US population of children and persons with type 1 diabetes.
61st Annual meeting/ADA scientific sessions, Philadelphia, PA June 20-26 2001.
Goudy K, Ellis T, Ottendorfer E, Song S, Wasserfall C, Flotte T, Atkinson M:
Interleukin-10 gene therapy utilizing adeno-associated virus vectors prevents type
1 diabetes in NOD mice. 61st Annual meeting/ADA scientific sessions,
Philadelphia, PA June 20-26 2001.
Song, S.; Goudy, K., Wasserfall, C., Wang, J., Ottendorffer, E., Ellis, T., Crawford,
J., Flotte, T., Atkinson, M. Adeno-Associated Virus (AAV2) Vector Mediated IL-10
Gene Delivery Prevents Type 1 Diabetes in NOD Mice. American Society for Gene
Therapy, 2001.
Zhang, Y.C.; Molano, R.D.; Pileggi, A.; Powers, M.; Wasserfall, C.: Brusko, T.;
Flotte, T.; Ellis, T.M.; Ricordi, C.; Atkinson, M.A.; Inverardi, L.: Adeno-Associated
Virus Mediated Interleukin-10 Gene Therapy Inhibits Autoimmune Diabetes
Recurrence in Syngeneic Islet Transplanted NOD Mice. American Diabetes
Association, 62nd Scientific Sessions, 2002.
Zhang, Y.C.; Molano, R.D.; Pileggi, A.; Powers, M.; Wasserfall, C.: Brusko, T.;
Flotte, T.; Ellis, T.M.; Ricordi, C.; Inverardi, L.; Atkinson, M.A: Adeno-Associated
Virus Mediated Interleukin-4 Gene Therapy Fails to Enhance Recurrence to
Normoglycemia in Syngeneic Marginal Mass Islet Transplants. American Diabetes
Association, 62nd Scientific Sessions, 2002.
Zhang, Y.C.; Molano, R.D.; Pileggi, A.; Powers, M.; Wasserfall, C.: Brusko, T.;
Flotte, T.; Ellis, T.M.; Ricordi, C.; Inverardi, L.; Atkinson, M.A: Adeno-Associated
Virus Mediated Interleukin-10 Gene Therapy Inhibits Autoimmune Diabetes
Recurrence in Syngeneic Islet Transplanted NOD Mice. American Society for
Gene Therapy, 2002.
Zhang, Y.C.; Molano, R.D.; Pileggi, A.; Powers, M.; Wasserfall, C.: Brusko, T.;
Flotte, T.; Ellis, T.M.; Ricordi, C.; Inverardi, L; Atkinson, M.A.: Adeno-Associated
Virus Mediated Interleukin-4 Gene Therapy Fails to Enhance Recurrence to
Normoglycemia in Syngeneic Marginal Mass Islet Transplants. American Society
for Gene Therapy, 2002.
Zhang, Y.C.; Molano, R.D.; Pileggi, A.; Powers, M.; Wasserfall, C.: Brusko, T.;
Flotte, T.; Ellis, T.M.; Ricordi, C.; Atkinson, M.A.; Inverardi, L.: Adeno-Associated
Virus Mediated Interleukin-10 Gene Therapy Inhibits Autoimmune Diabetes
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Recurrence in Syngeneic Islet Transplanted NOD Mice. American Society for
Transplantation, 2002.
Song, S.; Goudy, K.; Campbell-Thompson, M. ; Wasserfall, C.; Scott-Jorgensen,
M.; Wang, J.; Tang, Q., Crawford, J.M.; Atkinson, M.A.; Flotte, T.: Recombinant
AAV Mediated Alpha 1 Antitrypsin Gene Therapy Prevents Type 1 Diabetes in
NOD Mice. American Society for Gene Therapy, 2002.
Zhang, Y.C.; Molano, R.D.; Pileggi, A.; Powers, M.; Wasserfall, C.: Brusko, T.;
Flotte, T.; Ellis, T.M.; Ricordi, C.; Atkinson, M.A.; Inverardi, L.: Adeno-Associated
Virus Mediated Interleukin-4 Gene Therapy Fails to Enhance Recurrence to
Normoglycemia in Syngeneic Marginal Mass Islet Transplants. American Society
for Transplantation, 2002.
Zhang, Y.C.; A. Pileggi, R.D. Molano, E. Zahr, R. Poggioli, M. Powers,
C.Wasserfall, T. Brusko, M.S. Jorgensen, M.C. Thompson, J.M. Crawford, T.
Flotte, T.M. Ellis, C. Ricordi, M.A. Atkinson, L. Inverardi. Adeno-Associated Virus
Medicated Interleukin-10 Gene Therapy Inhibits Autoimmune Diabetes
Recurrence in Syngeneic Islet Transplanted NOD Mice. 6th Annual Meeting of the
Immunology of Diabetes Society. 2002.
Y.C. Zhang, R.D. Molano, A. Pileggi, J. Cross, M. Powers, C. Wasserfall, M.S.
Jorgensen, M.C. Thompson, J.M. Crawford, T. Flotte, T.M. Ellis, C. Ricordi, M.A.
Atkinson, L. Inverardi, IL-4 expressed from AAV transduced islet grafts fails to
improve the reversal of hyperglycemia in syngeneic and allogeneic islet
transplantation models. 6th Annual Meeting of the Immunology of Diabetes
Society. 2002.
C. Wasserfall, J. Cross, K. Goudy, M. Kapturczak, M. Powers, T.M. Ellis, M.A.
Atkinson. Anti-insulin immunity in nod mice, as assessed by insulin
Autoantibodies, associates with the efficacy of adoptive transfer of diabetes. 6th
Annual Meeting of the Immunology of Diabetes Society. 2002.
K. Goudy, C. Wasserfall, B. Burkhardt, T. Brusko, E. Sobel, S. Song, T. Ellis, T.
Flotte, M. Atkinson. Gene Therapy Using AAV-IL-10 Prevents Diabetes IN NOD
MICE in a dose and time dependent fashion through immunoregulatory
enhancement. 6th Annual Meeting of the Immunology of Diabetes Society. 2002.
Song, K. Goudy, M. Campbell-Thompson, C. Wasserfall, M. Scott-Jorgensen, J.
Wang, Q. Tang, J.M. Crawford, M.A. Atkinson, T.R. Flotte, Recombinant AAV
mediated alpha-1 antitrypsin gene therapy prevents type 1 diabetes in NOD mice.
6th Annual Meeting of the Immunology of Diabetes Society. 2002.
Goudy K, Burkhardt B, Wasserfall C, Sobel E, Song S, Ellis T, Clare-Salzler,
Flotte T, Atkinson M.: Immunomodulation of Antigen Presenting cells and
Induction of Regulatory T cells Prevents Type 1 Diabetes in NOD Mice Using
AAV-IL-10 Gene therapy. American Diabetes Association, 63rd Scientific Sessions,
2003.
Wilson SB, Pritchard L, Wasserfall C, Clare-Salzler M and Atkinson M.Temporal
Alterations in the Frequency of VαJαQ T cells in Type 1 diabetes. American
Diabetes Association, 63rd Scientific Sessions, 2003.
Kapturczak MH, Wasserfall CH, Loiler S, Campbell-Thompson M, ScottJorgensen M, Cross J, Crawford JM, Ellis TE, Flotte T, Atkinson MA.: Systemic
Gene Therapy with Interleukin-10 (IL-10) for Prevention of Type 1 Diabetes in
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NOD Mice: Comparison of Mutant ( I87A Substitution) to Recombinant Murine IL10. American Diabetes Association, 63rd Scientific Sessions, 2003.
Pearce, DA, Wasserfall, CH, Pritchard L, Ellis.TE, Chattopadhyay S, Atkinson
MA.: Humoral Immune markers of Type 1 Diabetes in Patients with the
Neurodegenerative Disorder Batten’s Disease. American Diabetes Association,
63rd Scientific Sessions, 2003.
Morales AE, Wasserfall C, Ellis T, Atkinson M, Silverstein J.: Adiponectin and
Cytokine Levels in Children with Diabetes. American Diabetes Association, 63 rd
Scientific Sessions, 2003.
M Kapturczak, C Wasserfall, T Ellis, M.A. Atkinson, A Agarwal.: Heme
oxygenase-1 modulates early inflammatory responses: Evidence from the HO-1
deficient mouse. American Society of Nephrology, 2003.
S. Chen, M. Kapturczak, C. Wasserfall, O.Y. Glushakova, L. Zhang, P. Cruz, M.
Campbell-Thompson, W.W. Hauswirth, K.I. Berns, K.M. Madsen, B.P. Croker, M.A.
Atkinson, T.R. Flotte, C.CTisher, A. Agarwal.: Adeno-Associated Virus (type 1)
Vector-Mediated Interleukin-10 Gene Delivery Attenuates Neointimal Proliferation
in Rat Aortic Allografts American Society of Nephrology, 2003.
Cushman JD, Wasserfall C, Huang Z, Ha G, Kapturczak MH, Ellis T, Atkinson M,
Petitto JM. : Immune reconstitution restores components of neurobehavioral
performance in Recombination Activation Gene-1 Knockout mice. Society for
Neuroscience 2003.
Davoodi-Semiromi, S. Litherland, G. Ghaffari, R-H. Fang, C. Wasserfall, C. Xia
and M. Clare-Salzler Unique Signature of Stat5 in Regulatory CD4+CD25+ T Cells.
7th Annual Meeting of the Immunology of Diabetes Society. 2004.
Wasserfall C, Huppmann M, Ziegler AG, Schwartz RF, Ellis TM, Atkinson MA,
and Bonifacio E: Leptin Concentration and Body Mass Index are Increased at a
very Early Age in Obese Children. American Diabetes Association, 64 th Scientific
Sessions, 2004.
Lu Y, Tang M, Wasserfall C, Choi Y-K, Gardmann T, Campbell-Thompson M,
Ellis T, Atkinson MA and Song S: Prevention of Type 1 Diabetes by Alpha 1
Antitrypsin Gene Therapy. American Diabetes Association, 64th Scientific
Sessions, 2004.
Zhang YC, Pileggi A, Molano RD, Wasserfall C, Campbell-Thompson M, Zahr E,
Poggioli R, Brusko T, Flotte T, Ricordi C, Atkinson M, and Inverardi L: AdenoAssociated Virus Mediated Interleukin-10 Gene Therapy Markedly Inhibits Islet
Allograft Rejection in NOD Mice. American Diabetes Association, 64th Scientific
Sessions, 2004.
Cresawn KO, Wasserfall C, Atkinson MA, Mah C, Fraites TJ, Zolotukhin I, Byrne
BJ: Cross-correction in Pompe mice after immunomodulation and hepatic delivery
of recombinant AAA5 and AAV8 vectors. American Society for Gene Therapy,
2004.
Lu YQ, Tang M, Wasserfall C, Choi YK, Gardmann T, Campbell-Thompson M,
Atkinson MA, Song SH: Alpha 1 antitrypsin gene delivery for preventing type 1
diabetes in NOD mice. American Society for Gene Therapy, 2004.
Brusko TM, Wasserfall CH, Clare-Salzler MJ, Schatz DA, Atkinson MA:
Functional defects and the influence of age on the frequency of CD4(+)CD25(+) T
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cells in type 1 diabetes. American Diabetes Association, 65th Scientific Sessions,
2005.
Tang M, Lu Y, Brusko T, Wasserfall C, Zhang B, Campbell-Thompson M,
Atkinson MA, Song S: Prevention of type 1 diabetes by AAT gene therapy is dose
and time dependent. American Diabetes Association, 65th Scientific Sessions,
2005.
Campbell-Thompson M, Lee CH, Wasserfall CH, Reifsynder PC, Tenace LM,
Chen J, Atkinson MA, Leiter EH: Obesity and beta-cell regeneration in
spontaneous leptin receptor mutation NOD/LtJ mice. American Diabetes
Association, 65th Scientific Sessions, 2005.
Brusko, T.M.; Wasserfall, C.; Atkinson, M.A.; Dynamics of CD4+CD25+ T Cells
and Soluble CD25 in Type 1 Diabetes. American Diabetes Association, 65th
Scientific Sessions, 2005.
Stalvey, M.; Wasserfall, C.; Brusko, T.; Flotte, T.R.; Schatz, D.; Atkinson, M.A.; A
Pro-Inflammatory State and Hyperglycemia are Associated with a Cystic Fibrosis
Related Diabetes Mouse Model. American Diabetes Association, 65th Scientific
Sessions, 2005.
Wasserfall C, Schwartz RF, Simon G, Binns S, Brusko T, Stalvey M,
Clare−Salzler M, Song S, a Campbell−Thompson M, Flotte T, Atkinson: A
Dichotomous Role for Interleukin−10 in the Pathogenesis of Type 1 Diabetes
American Diabetes Association, 65th Scientific Sessions, 2005.
Stalvey, M.; Wasserfall, C.; Brusko, T.; Schatz, D.; Atkinson, M.A.; Flotte, T.R.; A
Pro-Inflammatory State is Associated with Streptozoticin-Induced Hyperglycemia
in Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Knockout
Mice. Lawson Wilkins Pediatric Endocrine Society, 2005.
Stalvey M; Muller C; Wasserfall C; Brusko T; Schatz D; Atkinson M; Flotte TR:
Modeling Cystic Fibrosis Related Diabetes In Cftr-Deficient Mice: Effects Of Cftr
Genotype On Glycemic Control After Sub-Lethal Beta Cell Injury Or Pulmonary
Sensitization And Challenge. NACFC meeting 2005.
Simon G, Wasserfall C, Byrne B, Atkinson M: Adeno-Associated Viral Gene
Therapy for the Prevention of Type 1 Diabetes in the NOD Mouse. 8th Annual
Meeting of the Immunology of Diabetes Society. 2005. Japan.
Lee CH, ChenYG, Chen J, Reifsnyder PC, Serreze DV, Clare-Salzler M,
Rodriguez M, Wasserfall C, Atkinson MA, Leiter EH: Suppressed Autoimmunity in
Leptin Receptor Mutated NOD-Leprdb-5j/Lt Mice. 8th Annual Meeting of the
Immunology of Diabetes Society. 2005. Japan.
Huerta M, Jaques C, Mendosa P, Schwartz RF, Wasserfall C, Nadler J, Atkinson
M: Decreased Adiponectin/Leptin ratio is Associated with Inflammation, Insulin
Resistance and Endothelial and Monocyte Activation in Obese Children. American
Diabetes Association, 66th Scientific Sessions, 2006.
Brusko T, Wasserfall C, Atkinson M: CD25 Stability Controls the In Vitro
Suppressive Capacity of CD4+CD25+ Regulatory T Cells. American Diabetes
Association, 66th Scientific Sessions, 2006.
M. Stalvey, F. Schwartz, C. Muller, T. Brusko, C. Wasserfall, D. Schatz, T. Flotte
and M. Atkinson: Increased Inflammatory Reactivity of Cystic Fibrosis
Transmembrane Conductance Regulator Deficient (CFTR-/-) Mice Is Not
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Associated with Insulin Resistance. American Diabetes Association, 66 th Scientific
Sessions, 2006.
Zhang B, Lu Y, Campbell-Thompson M, Wasserfall C, Atkinson M, Song S: Alpha
1 antitrypsin protects against islet cell apoptosis. American Diabetes Association,
66th Scientific Sessions, 2006.
Stalvey M, Pashuck T, Wasserfall C, Atkinson MA, Flotte TR: Cystic Fibrosis
Related Diabetes Mouse Model Resembles Clinical Disease. North American
Cystic Fibrosis Conference, 2006.
A Braun, J George, T Brusko, R Joseph, C Wasserfall, MA Atkinson, A Agarwal,
MH Kapturczak: Abnormalities of regulatory T cells in heme oxygenase-1 knockout
mice. American Society for Nephrology Meeting, 2006.
A Braun, J George, R Joseph, T Brusko, C Wasserfall, MA Atkinson, A Agarwal,
MH Kapturczak: Heme oxygenase-1 (HO-1) expression in antigen
presenting cells (APC) is required for proper function of CD4+CD25+
regulatory T cells (Treg). American Society for Nephrology Meeting, 2006.
Goldstone AP, Johnstone KA, Futtner CR, Silver X, Wasserfall C, Stoll ML, Reep
RL, Atkinson MA, Resnick JL, Driscoll DJ: Phenotyping of adult mice with a
deletion of the Prader-Willi syndrome imprinting center. PWS Association USA
Buffalo, New York 2006.
M Huerta, A Weltman, C J, P Mendosa, S Street, HL Viener, G Francois, C
Wasserfall, M Atkinson, J Silverstein, J Nadler.: Role of Adipokines and
Inflammation in the Development of Type 2 Diabetes in Adolescents. PAS
meeting, 2007.
M Escobar-Douglas, M Atkinson, C Wasserfall, N Li, R Caicedo, J Neu, DA.
Schatz.: Sodium Butyrate Prevents Type 1 Diabetes in Biobreeding Diabetes
Prone (BBdp) Rats. PAS meeting , 2007.
Zhang B,Tang M, Wasserfall, C, Atkinson M, Song S.: Alpha 1 antitrypsin (AAT)
inhibits granzyme B activity and NK cell killing. American Diabetes Association,
67th Scientific Sessions, 2007.
Haller MJ, Viener H, Brusko T, Wasserfall C, McGrail K, Staba S, Cogle C,
Atkinson M, Schatz DA.: Insulin requirements, HbA1c, and stimulated C-peptide
following autologous umbilical cord blood transfusion in children with T1D.
American Diabetes Association, 67th Scientific Sessions, 2007.
Xue S, Loiler S, Lira A, Cruz P, Wasserfall C, Schatz D, Flotte T, Atkinson M,
Ramiya V.: Reversal of Diabetes in Streptozotocin Induced Diabetic Mice
Following Direct Intra-Pancreatic Gene Delivery of Adeno-Associated Virus Vector
Encoding Glucagon-Like Peptide-1 (GLP-1). American Diabetes Association, 67th
Scientific Sessions, 2007.
Viener H, Brusko T, Wasserfall C, McGrail K, Staba S, Cogle C, Atkinson M,
Schatz DA, Haller MJ.: Changes in regulatory T cells following autologous
umbilical cord blood transfusion in children with type 1 diabetes. American
Diabetes Association, 67th Scientific Sessions, 2007.
Jie HB, Lin H, Lee H, Wilson B, Viener H, Brusko T, Wasserfall C, Clare-Salzler
M, Atkinson MA.: The critical roles of IL-2 in iNKT cell mediated tolerance.
American Diabetes Association, 67th Scientific Sessions, 2007.
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Brusko T, Wasserfall C, McGrail K, Huegel A, Moore M, Schatz D, Atkinson M.:
Regulatory T cells require serum for suppression of effector T cell proliferation and
express stable membrane-bound CD25. American Diabetes Association, 67th
Scientific Sessions, 2007.
Escobar-Douglas M, Schatz D, Atkinson M, Wasserfall C, Li N, Caicedo R, Neu
J.: Sodium butyrate prevents type 1 diabetes in biobreeding diabetes prone
(BBDP) rats. American Diabetes Association, 67th Scientific Sessions, 2007.
Lu Y, Zhang B, Choi YK, Campbell-Thompson M, Wasserfall C, Brantly M,
Atkinson M, Song S.: Induction of type 1 hypersensitivity in nod mice subjected to
alpha 1-Antitrypsin (AAT) protein therapy. American Diabetes Association, 67th
Scientific Sessions, 2007.
Parker M, Wasserfall C, Campbell-Thompson M, Frances P, Atkinson M.:
Combination therapy utilizing murine anti-thymocyte globulin (ATG) and rapamycin
for the reversal of overt type 1 diabetes in NOD mice. American Diabetes
Association, 67th Scientific Sessions, 2007.
Campbell-Thompson M, Dixon L, Chen M, Monroe M, Wasserfall CH, McGuigan
JM, Crawford JM, Atkinson MA.: Chronic pancreatitis increases adult beta cell
replication. American Diabetes Association, 67th Scientific Sessions, 2007.
Stalvey M, Brusko T, Muller C, Wasserfall C, Schatz D, Flotte T, Atkinson M.:
Hyperglycemia exacerbates TH2 immune reactivity in a cystic fibrosis related
diabetes mouse model. American Diabetes Association, 67th Scientific Sessions,
2007.
Huerta M, Jaques C, Mendosa P, Wasserfall C, Silverstein J, Atkinson M, Nadler
J.: Role of inflammation, oxidative stress and adipokines in the development of
insulin resistance and altered glucose homeostasis in obese youth. American
Diabetes Association, 67th Scientific Sessions, 2007.
Molano RD, Pileggi A, Song S, Zahr E, Sanjose S, Wasserfall C, Ricordi C,
Atkinson MA, Inverardi L.: The role of hurnoral immunity in alpha 1 antitrypsinmediated islet allograft survival prolongation. American Diabetes Association, 67th
Scientific Sessions, 2007.
Song S, Molano RD, Pileggi A, Lu Y, Wasserfall C, Campbell-Thompson M, Zahr
E, Sanjose, S, Ricordi C, Atkinson MA, Inverardi L.: Islet allograft survival under
systemic alpha 1 antitrypsin treatment: Comparison of gene therapy versus protein
therapy. American Diabetes Association, 67th Scientific Sessions, 2007.
Song S, Pileggi A, Molano RD, Lu Y, Campbell-Thompson M, Wasserfall C, Zahr
E, San Jose, SS, Ricordi C, Inverardi L, Atkinson MA.: Alpha 1 antitrypsin therapy
does not prevent recurrence of autoimmunity in NOD mice. American Diabetes
Association, 67th Scientific Sessions, 2007.
Constantinidis I, Flint J, Wasserfall C, Cambell-Thompson M, Atkinson M,
Blackband S.: MR imaging of islets and the pancreas. American Diabetes
Association, 67th Scientific Sessions, 2007.
Pileggi A, Molano RD, Song S, Zahr E, San Jose S, Villate S, Wasserfall C,
Ricordi C, Atkinson M, Inverardi L.: Effects of alpha-1 antitrypsin on islet allograft
survival in spontaneously diabetic NOD mice. American Diabetes Association, 67th
Scientific Sessions, 2007.
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Stalvey, M., Mueller, C., Brusko, T., Wasserfall, C., Parker, M., Atkinson, M., and
Flotte, T. Altered Cytokine Production In Diabetic CFTR-Deficient Mice Persists
Independent Of Glucose Concentration. NACF 2007.
Stalvey, M., Pashuck, T., Franz, S., Altman, M., Atkinson, M., Wasserfall, C.,
Wronski, T., and Flotte, T. Cftr-Deficient Mice Have Increased Bone Mineral
Density (BMD) Measured By Peripheral Quantitative Computed Tomography
(pQCT). NACF 2007.
Huang Y, Parker M, Xia C, Peng R, Wasserfall C, Clare-Salzler M, Atkinson M,
Womer K.: Murine anti-thymocyte globulin administration alters dendritic cell
profile and function in NOD mice. American Transplant Society, 2007.
Molano RD, Pileggi A, Song SH, Zahr E, Jose SS, Fort A, Wasserfall C, Ricordi
C, Atkinson MA, Inverardi L, Molina J.: Prolonged islet allograft survival by Alpha-1
antitrypsin: The role of humoral immunity. Xenotransplantation 14 (5): 497-497,
2007
Pileggi A, Molano RD, Song SH, Jose SS, Villate S, Wasserfall C, Ricordi C,
Atkinson MA, Inverardi L.: Alpha-1 antitrypsin treatment of spontaneously diabetic
NOD mice receiving islet allografts. Xenotransplantation 14 (5): 497-498, 2007
Xue S, Wasserfall CH, Parker MJ, McGrail KM, McGrail SM, Moore MC, Brusko
TM, Schatz DA, Atkinson MA, Haller MJ.: Exenatide enhances beta-cell mass,
increases beta-cell division and decreases apoptosis but does not reverse
hyperglycemia in new onset NOD mice. 9th Annual Meeting of the Immunology of
Diabetes Society. 2007. Miami, USA.
Molano R, Pileggi A, Song S, Zahr E, SanJose S, Molina J, Fort A, Wasserfall C,
Ricordi C, Atkinson MA, Inverardi L.: Role of humoral immunity in alpha-1
antitrypsin induced prolongation of islet allograft survival. 9 th Annual Meeting of the
Immunology of Diabetes Society. 2007. Miami, USA.
Parker M, Xue S, Song XA, Wasserfall C, Atkinson M.: Reversal of overt type 1
diabetes in the NOD mouse via a combination therapy of murine anti-thymocyte
globulin and alpha-1 antitrypsin. 9th Annual Meeting of the Immunology of Diabetes
Society. 2007. Miami, USA.
Pileggi A, Molano RD, Song S, Zahr E, SanJose S, Villate S, Wasserfall C,
Ricordi C, Atkinson MA, Inverardi L.: Effect of alpha-1 antitrypsin treatment on the
survival of islet allografts in spontaneously diabetic NOD mice. 9th Annual Meeting
of the Immunology of Diabetes Society. 2007. Miami, USA.
Ramiya V, Xue S, Lira A, Lira V, Wasserfall C, Criswell D, Schatz D, Atkinson M.:
Intra-pancreatic gene delivery to induce islet regeneration using adeno-associated
virus vector encoding glucagon-like peptide-1. 9th Annual Meeting of the
Immunology of Diabetes Society. 2007. Miami, USA.
Song S, Pileggi A, Molano RD, Lu Y, Campbell-Thompson M, Wasserfall C, Zahr
E, SanJose S, Ricordi C, Inverardi L, Atkinson MA.: Alpha-1 antitrypsin treatment
of spontaneously diabetic NOD mice does not prevent recurrence of autoimmunity.
9th Annual Meeting of the Immunology of Diabetes Society. 2007. Miami, USA.
Song S, Molano RD, Pileggi A, Lu Y, Wasserfall C, Campbell-Thompson M, Zahr
E, SanJose S, Ricordi C, Inverardi L, Atkinson MA.: Alpha-1 antitrypsin:
comparison of systemic gene therapy versus protein treatment on treatment on
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islet allograft survival. 9th Annual Meeting of the Immunology of Diabetes Society.
2007. Miami, USA.
Pashuck, T., Franz, S., Altman, M., Atkinson, M., Wasserfall, C., Wronski, T.,
Flotte, T., and Stalvey, M. Murine Model for Cystic Fibrosis Bone Disease
Demonstrates Sex-Related Differences in Bone Formation. NACFC 2008.
Portnow, L., Mueller, C., Greer, J., Rojas, M., Wasserfall, C., Atkinson, M., Flotte,
T., and Stalvey, M. Recombinant Adeno-Associated Virus Serotype 1 (rAAV1)Mediated Alpha-1 Antitrypsin (AAT) Gene Therapy in a Cystic Fibrosis-Related
Diabetes (CFRD) Mouse Model. NACFC 2008.
Burkhart, B., Mueller, C., Parker, M., Kenworthy, B., Wasserfall, C., Atkinson, M.,
Flotte, T., and Stalvey, M. Increased IL-8 Receptors on Cystic Fibrosis (CF)
Monocytes: A Novel Contribution to Increased Immune Reactivity and CF Related
Bone Disease. NACFC 2008.
Polyak S, Dixon S, Wasserfall C, Mach A, Mah C, Kevil C, Valentine J.:
Alterations in Mucosal Cytokine levels reflect acute inflammation but not chronic
inflammation in the Murine DSS model of Colitis. Chrohn’s and Colitis
Conference, 2008.
Haller MJ, Wasserfall C, Mcgrail K, Viener H, Cintron M, Gaitan S, Brusko T,
Wingard J, Cogle C, Kelly S,. Slayton WB, Atkinson MA, Schatz DA: Autologous
Umbilical Cord Blood Transfusion in Very Young Children with T1D: 1 Year
Follow-Up. American Diabetes Association, 69th Scientific Sessions, 2009.
Gianani R, Campbell-Thompson M, Wasserfall C, Pugliese A, Kent S, Hering B,
West E, Steck A, Bonner-Weir S, Eisenbarth G, Atkinson M: Dimorphic
Histopathology of Long Standing Childhood Diabetes. American Diabetes
Association, 69th Scientific Sessions, 2009.
Ma O, Lu Y, Li W, Wasserfall C, Haller M, Campbell-Thompson M, Brantly M,
Schatz D, Atkinson M, Song S: Prevention and Reversal of Type 1 Diabetes by
Alpha 1 Antitrypsin (AAT) Given Intradermally in NOD Mice. American Diabetes
Association, 69th Scientific Sessions, 2009.
Ramiya V, Wasserfall C, Xue S, Parker M, Haller M, Schatz D, Atkinson M:
Combination Therapy with IL-2 and Rapamycin Reverses Type 1 Diabetes in NonObese Diabetic (NOD) Mice. American Diabetes Association, 69th Scientific
Sessions, 2009.
Ize-Ludlow D, Luzardo Y, Wasserfall C, Schatz D, Atkinson M, Mathews C:
Progressive Erosion of Beta Cell Function Precedes the Onset of Type 1 Diabetes
in the NOD Mouse. American Diabetes Association, 69th Scientific Sessions, 2009.
Rowe PA, Campbell-Thompson M, Wasserfall CH., Fernanda Martino M,
Albanese-O'Neil A, Schatz D, Atkinson M: Network for Pancreatic Organ Donors
with Type 1 Diabetes (nPOD): Progress and Donor Demographics. American
Diabetes Association, 69th Scientific Sessions, 2009.
Zhang B, Wasserfall C, Atkinson M, Song S: Alpha 1-Antitrypsin (AAT) Enhances
the Function of Pancreatic Beta-Cells. American Diabetes Association, 69th
Scientific Sessions, 2009.
Bierschenk L, Alexander J, Wasserfall C, Haller M, Schatz D, Atkinson M:
Suboptimal Vitamin D Levels are not Limited to Those with Type 1 Diabetes.
American Diabetes Association, 69th Scientific Sessions, 2009.
117. Laning JC, Brehm MA, Leif J, Wasserfall C, Atkinson MA, Shultz LD, Greiner DL.:
Diabetogenic Function of Donor Splenocytes from Type 1 Diabetes (T1D) Patients
in Humanized Mice. 10th Annual Meeting of the Immunology of Diabetes Society.
2009. Malmo, Sweden.
118. Miersch S, Sibani S, Logvinenko T, Wasserfall C, Atkinson M, Schatz D., LaBaer
J: Serological Profiling for T1D-Associated Autoantibodies Using The Nappa
Platform. 10th Annual Meeting of the Immunology of Diabetes Society. 2009.
Malmo, Sweden.
119. Rowe P, Campbell-Thompson M, Wasserfall C, Fernanda-Martino M, AlbaneseO’Neill M, Atkinson M, Schatz D.: Clinical Findings in U.S. Organ Donors with
Type 1 Diabetes Mellitus. American Diabetes Association, 70th Scientific Sessions,
2010.
120. Parker M, Wasserfall C, Xue S, Campbell-Thompson M, Mathews C, Schatz D,
Haller M, Atkinson M.: Granulocyte Colony-Stimulating Factor Enhances Both
ATG and Anti-CD3 mAb-Mediated Reversal of Type 1 Diabetes in NOD Mice.
American Diabetes Association, 70th Scientific Sessions, 2010.
121. Han Z, Garrigan E, Atkinson M, Wasserfall C, Clare-Salzler MJ, Amick M,
Litherland SA.: Epigenetic Dysfunction in Autoimmune Diabetes: Persistent
Monocyte STAT5 Phosphorylation Promotes Epigenetic Dysregulation of GMCSF-Induced PGS2/COX2 Expression in Type 1 Diabetes. American Diabetes
Association, 70th Scientific Sessions, 2010. American Diabetes Association, 70th
Scientific Sessions, 2010.
122. Campbell-Thompson M, Rowe PA, Wasserfall CH, Pietras R, Albanese-O'Neill A,
Gianani R, Schatz DA, Atkinson MA.: Histopathology of Type 1 Diabetes in U.S
Organ Donors. American Diabetes Association, 70th Scientific Sessions, 2010.
123. Garrigan E, Han Z, Seydel F, Belkin NS, Riggs C, Amick M, Cdebaca A, Pilant T,
Bober R, Wasserfall C, Atkinson M, Clare-Salzler MJ, Morel L, McDuffie M,
Literland SA.: A Model for Studying the Impact of Nurture on Nature: Development
of Diabetes in Multicongenic Mice with an Epigenetic Gene Expression
Dysregulation Defect from the Nonobese Diabetic Mouse (NOD). American
Diabetes Association, 70th Scientific Sessions, 2010.
124. Myhr C, Wasserfall C, Haller M, Schatz D, Atkinson M.: Unique Gene Expression
Profiles from Peripheral Blood in Subjects with Type 1 Diabetes. American
Diabetes Association, 70th Scientific Sessions, 2010.
125. Rowe P, Wasserfall C, Fernanda-Martino M, Albanese-O'Neill A, Schatz D,
Atkinson M.: Islet Glucagon Staining in Pancreata from Diabetic Organ Donors
May Be Inversely Related to In-Vivo β-Cell Insulin Function. American Diabetes
Association, 70th Scientific Sessions, 2010.
126. Blanton D, Hong P, Alexander JJ, Myhr C, Han Z, Wasserfall C, Schatz D,
Atkinson M.: QRT-PCR and Custom Immune System Phenotyping Arrays for
Characterizing Gene Expression in Type 1 Diabetes. American Diabetes
Association, 70th Scientific Sessions, 2010.
Invited Lectures/Seminars/Workshops
(National/International)
“Islet cell antigens/antibodies and their predictive value for Type 1 Diabetes.”
C Wasserfall and NK Maclaren. Research Symposium: Prevention of Type 1 Diabetes,
Kirkkonummi, Finland. May 6-8 1996.
Akerblom HK, Knip M: Prevention of IDDM: strategies based on new observations of
molecular pathogenesis. Workshop held in Majvik, Kirkkonummi, Finland, 6-8 May
1996. Diabetologia : 40(6):743-748, 1997.
Rapporteur: 4th JDF International Conference. March 16-19 1997 Athens, Greece.
Honeyman M, Wasserfall C, Nerup J, Rossini A: Prediction and prevention of IDDM.
Diabetologia 40: Suppl 3:B58-B61, 1997.
Consultant: Centers for Disease Control and Prevention. Update on autoantibody
screening strategies in the prediction of IDDM. CDC Atlanta,GA USA 1-3 July 1998.
Stretching the Blood Spot: CDC workshop on the role of dried blood spots in diabetes
prevention research. Atlanta,GA USA Feb, 16-17, 1999.
Technical Workshop on Dried Blood Spots in Diabetes Research. The National Diabetes
Laboratory, CDC. Stone Mountain,GA USA August 16-17, 1999.
Stretching the Blood Spot: CDC Workshop on the applications of multi-analyte fluorescent
bead assays. Atlanta, GA USA April 2, 2001.
Invited seminar: Applications of Luminex technology in Type 1 Diabetes research. CDC.
Atlanta,GA USA June 18, 2002.
Co- organizer: Second Murine Autoantibody workshop: 6th Immunology of Diabetes
Society meeting. Copper Mountain, CO. USA Oct 3-6 2002.
Yu L, Eisenbarth G, Bonifacio E, Thomas J, Atkinson M, Wasserfall C.: The Second
Murine Autoantibody Workshop: Remarkable Concordance of Radiobinding Assays to
Identify Insulin Autoantibodies in Non-Obese Diabetic Mice. Annals of the New York
Academy of Science 1005: 1-12, 2003.
NIH/NINDS-Sponsored Workshop on Glutamic Acid Decarboxylase Autoimmunity in
Battens Disease. Bethesda, MD. USA November 13-14 2003.
“Insights from serum and plasma ( inflammatory cytokines and adipokines)”
Mark Atkinson and Clive Wasserfall. 9th EASD/JDRF Oxford Workshop, Mechanisms
and Prevention of Type 1 Diabetes. Oxford, UK. 6-9 August 2004.
Invited seminar: Luminex technology and Type 1 Diabetes research. Clive Wasserfall
General Clinical Research Centers (GCRC) National Annual Meeting April 27 - May 1,
2005 Washington, DC.
Consultant: TrialNet Washington DC. “Serum Cytokines”. May 16th 2007.
“Butyrate and gut barrier function” Clive Wasserfall and Martha Douglas Escobar. 12th
EASD/JDRF Oxford Workshop, Role of the Gastrointestinal Tract in the Pathogenesis of
Type 1 Diabetes. Oxford, UK 3-6 August, 2007.