Course Syllabus HMS -317 Human Medical Science 7 School of Pharmacy, Walailak University 1. 2. 3. 4. 5. 6. 7. Course Code : HMS-317 Course Unit: 1 (4-0-8) Course Title: Human Medical Science 7 School: School of Pharmacy Trimester: 1st (Third year student) Academic Year: 2009 List of Lecturers/Instructors: 7.1. Course director team 1) Mr. Attarat Pattanawongsa M.Sc. (Pharmacology), B.Sc. (Med. Tech.) 2) Mr. Wichai Phiboon Pharm.D (Doctor of Pharmacy) 7.2. Special Lecturers 1) Assoc. Prof. Dr. Kitpramuk Tantayaporn M.D. 7.3. Lecturers 1) Prof. Dr. Thirayudh Glinsukon (School of Medicine) 2) Prof. Dr. Voranunt Suphiphat (School of Medicine) 3) Assoc. Prof. Dr. Taweeporn Sittiracha (School of Medicine) 4) Dr. Apichart Ngernsoungnern (School of Medicine) 5) Dr. Piyada Ngernsoungnern (School of Medicine) 6) Dr. Rapheeporn Khwanchuea (School of Medicine) 7) Mr. Attarat Pattanawongsa (School of Pharmacy) 8) Miss Apichaya Chanawong (School of Pharmacy) 9) Mr. Wichai Phiboon (School of Pharmacy) 10) Mr. Thawatchai Lukseng (School of Allied Health Sciences and Public Health) 11) Miss Salinee Chaiyakul (School of Allied Health Sciences and Public Health) 7.4. Course Co-ordinator 1) Mr. Attarat Pattanawongsa School of Pharmacy, Academic Building 8 Tel : 075-672716 e-mail : pattarat@wu.ac.th 2) Mr. Wichai Phiboon School of Pharmacy, Academic Building 8 Tel : 075-672765 e-mail : pwichai@wu.ac.th 1 8. Prerequisite: 9. Course Status: 10. Degree Title: 11. Programme: 12. Teaching hours: HMS-111 Human Medical Science 1 Compulsary Bachelor of Pharmacy School of Pharmacy, Walailak University Undergraduate Program Lecture 4 hours/week (Total of 12 weeks) Self-directed learning (SDL) 8 hours/week 13. Course Description: Structural and functional of endocrine glands produced several hormones, physiological effect of several hormone on controlling metabolism and functions of various cells and organs in the body, including structure and function of reproductive organs with emphasis on clinical abnormality, pathophysiological and pharmacological aspects related to regulation of these hormonal dysfunctions. 14. Course Objectives: 14.1 General objectives: Students should be understand the structural and functional of endocrine glands produced several hormones, physiological effect of several hormone on controlling metabolism and functions of various cells and organs in the body, including structure and function of reproductive organs with emphasis on clinical abnormality, pathophysiological and pharmacological aspects related to regulation of these hormonal dysfunctions. 14.2 Behavioral objectives: In the end of the course, students should be able to : 1) Describe the function of hormones including proliferation and development, nutrition and metabolism, calcium homeostasis, and fluid and blood pressure controlling. 2) Describe mechanism of hormone in the cellular and molecular level. 3) Describe microanatomy and physiology, causes of disorders and diseases, functional abnormality of hypothalamus and pituitary gland, thyroid gland, parathyroid gland, Islet of Langerhan gland (pancrease), and adrenal gland including drugs used in this disease/condition. 4) Describe microanatomy and physiology, causes of disorders and diseases, functional abnormality of reproductive system (male and female) including drugs used in this disease/condition. 5) Students team can use information technology to search literatures and can analyze, criticize, synthesize and modify information in problems solving. 2 14.2 Weekly course content: Content Week 1 Week May 25th , 2009 Lecture 1: Fundamental concept of endocrinology Lecture 2: Anatomy, Histology and physiology of Hypothalamus & Pituitary gland May 27th , 2009 Lecture 3: Disorders of Hypothalamus & Pituitary gland 2ndWeek Lecture 4: Hypothalamic & Pituitary Hormones June 1st, 2009 Lecture 5: Anatomy, Histology and physiology of Thyroid & Parathyroid Glands Lecture 6: Calcium Homeostasis rd June 3 , 2009 Lecture 7: Disorders of Thyroid (Pathophysiology of Thyroid diseases) rd 3 Week Problem Based Learning (PBL) June 8th, 2009 PBL 1: Mrs. Uthai Jaidee (Meeting 1) Lecture 8: Thyroid hormone & Antithyroid drugs June 10th, 2009 Lecture 9: Anatomy, Histology and physiology of Adrenal gland 4th Week Lecture 10: Disorders of Adrenal gland (Pathophysiology of Adrenocortical Disorders) June 15th, 2009 Lecture 11:Anatomy, Histology and physiology of endocrine pancrease Self-Directed Learning 1 (SDL 1): Endocrine tumor June 17th, 2009 Time Room No. Lecturer 13.00-15.00 10.00-11.00 01209 01209 Taweeporn Rapheeporn 11.00-12.00 01209 Taweeporn 13.00-14.00 14.00-15.00 01209 01209 Attarat Rapheeporn 10.00-11.00 11.00-12.00 01209 01209 Taweeporn Taweeporn 13.00-15.00 (xxxx) 10.00-11.00 11.00-12.00 01209 01209 Wichai and staffs Apichaya Thirayudh 13.00-14.00 01209 Thirayudh 14.00-15.00 01209 Rapheeporn 10.00-12.00 01209 Attarat/ Thirayudh 13.00-15.00 (xxxx) 10.00-11.00 01209 Wichai and staffs Rapheeporn 11.00-12.00 01209 Wichai st 5th Week June 22nd, 2009 June 24th, 2009 Problem Based Learning (PBL) PBL 1: Mrs. Uthai Jaidee (Meeting 2) Lecture 12: Disorders of the Endocrine Pancreas (Pathophysiology of Selected Endocrine Pancreatic Disorders) Lecture 13: Insulin and Glucagon 3 Lecture Examination 1 (lect. 1-10; 11 h.) 17.00-19.00 (xxxx) Lecture 14: Oral antidiabetic Agents Self-Directed Learning 2 (SDL 2): Anti-obesity drugs 13.00-15.00 10.00-12.00 01209 01209 Wichai Wichai Lecture 15: Principles of reproductive system and sex hormone Lecture 16: Anatomy, Histology and physiology : Endocrinology of Male Reproduction Lecture 17: Disorder of Male Reproductive system (Pathophysiology of male Reproductive Tract Disorders) Holiday 1: Buddhist Lent Day 13.00-14.00 01209 Rapheeporn Problem Based Learning (PBL) PBL 2: Mrs. Chadaporn Natong (Meeting 1) Lecture 18: The Testis (Androgens & Anabolic Steroids, Antiandrogens, & Male Contraception) 13.00-15.00 (xxxx) 10.00-12.00 01209 Wichai and stuffs Attarat Lecture 19: Anatomy and physiology : Endocrinology of Female Reproduction Lecture 20: Disorder of female Reproductive system Lecture Examination 2 (lect.11-18; 11 h.) 13.00-15.00 01209 Thawatchai 10.00-12.00 17.00-19.00 01209 (xxxx) Kitpramuk Lecture 21: The Ovary (Estrogens, Progestins, Other Ovarian Hormones, Oral Contraceptives, Inhibitors & Antagonists, & Ovulation-Inducing Agents) Self-Directed Learning 3 (SDL 3): Erectile dysfunction 13.00-16.00 01209 Wichai 10.00-12.00 01209 Kitpramuk Problem Based Learning (PBL) PBL 2: Mrs. Chadaporn Natong (Meeting 2) Lecture 22: Disorder of lipid metabolism and obesity August 5th,2009 Lecture 23: Rational Prescribing & Prescription Writing 13.00-15.00 (xxxx) 10.00-11.00 11.00-12.00 01209 01209 Wichai and stuffs Voranunt Wichai June 24nd, 2009 6th Week June 29th, 2009 July 1st , 2009 7th Week July 6 , 2009 th July 6th , 2009 8th Week July 13th , 2009 July 15th , 2009 14.00-16.00 Salinee 16.00-17.00 Thirayudh 10.00-12.00 9th Week July 20th , 2009 July 22nd , 2009 July 22th , 2009 10th Week July 27th , 2009 July 29th , 2009 11th Week August 3rd,2009 4 Demonstrate Laboratory : microanatomy and Histology of Endocrine system 12th Week August 10th,2009 Lecture 24: Toxic response of endocrine system August 12th,2009 Holiday 2: H.M. The Queen, s Birthday August 21th,2009 Final Lecture Examination (lect. 19-24; 12 h.) 13.00-16.00 Laboratory room 13.00-16.00 10.00-12.00 16.00-18.00 01209 Piyada/Apichart Thirayudh (xxxx) 14.3 Teaching-Learning Procedure 1) Lectures 24 sessions, totaling 33 hours 2) Self-Directed Learning (SDL) 3 sessions, totaling 6 hours 3) Problem-Based Learning (PBL) 2 Scenarios, totaling 8 hours 4) Examination 3 sessions 14.4 Instructional Media - Course Lecture Handouts/Laboratory Manuals/Textbooks (Each group of students will be given 1 set of 16 textbooks) and CD from some textbooks. - Power Point Slides/Transparency - Videos to supplement lectures and SDL 14.5 Learning Evaluation 1) Objective Test Questions(MCQ)/Short Answer Questions/Case-Study Cases - Written Tests: Weight Score = 77% 2) Learning Process - Problem-Based Learning (PBL): Weight Score = 12% - Self-Directed Learning (SDL): Weight Score = 6% - Attentions: 5% The course’s summative evaluation employs alphabetical attributes in grading the students’ learning achievement levels in correspondence with their numeric values in the evaluation scale as follows: Alphabetical Grades Meanings Score Values A Excellent 4.00 B+ Very Good 3.50 B Good 3.00 + C Fairly Good 2.50 C Fair 2.00 D+ Poor 1.50 D Very Poor 1.00 F Fail 0.00 5 15. Supplementary Reading: Compulsory: 1) Moore, K.L. and Agur, A.M.R (2002). Essential Clinical Anatomy, 2nd edition, Lippincott Williams & Wilkins. 2) Kurt, E.J. (1991). Histology and Cell Biology. Williams & Wilkins, Baltimore, Maryland. 3) Levy, M.N., et al. (2006). Berne & Levy Principles of Physiology. 4th edition, Mosby, St. Louis MO. 4) Kumar, V., Cotran, R.S. and Robbins, S.L. (2002). Robbin Pathologic of Disease, 6 th edition. W.B. Saunders Co., Philadelphia. 5) Brunton LL., Parker KL., Murri N., Blumenthal DK., ed. Goodman & Gilman’s The pharmacological basis of therapeutics. 11th ed. New York: The McGraw-Hill; 2006. 6) Katzung BG. Basic & clinical pharmacology. 10th ed. n.p.: McGraw-Hill Companies; 2007. 7) Lacy CF, Armstrong LL, Goldman PM, Lance LL. Drug information handbook. 12thed. Ohio: LexiComp Inc; 2004. 8) Waller DG., Renwick AG., and Hillier K. Medical Pharmacology and therapeutics. 2nd ed. n.d.: Elsevier Limited; 2005. 16. Course Teaching-Learning Evaluation: 1) Individual student is obliged to evaluate their lecturers and instructors 2) The course evaluation is done via WU-IT The course lecturers and instructors can have access to their students’ evaluation results for their teaching improvement. 6 Classroom time table of HMS -317 (Human medical Science 7) 1 (4-0-8) Week Date/Time 8.00-9.00 9.00-10.00 10.00-11.00 11.00-12.00 Lecture 2: Anatomy, Histology and physiology of Hypothalamus & Pituitary gland Lecture 3: Disorders of Hypothalamus & Pituitary gland May 25th , 2009 1 May 27th , 2009 Lecture 4: Hypothalamic & Pituitary Hormones June 1st, 2009 2 June 3 , 2009 rd Lecture 6: Calcium Homeostasis June 10th, 2009 15.00-16.00 Lecture 5: Anatomy, Histology and physiology of Thyroid & Parathyroid Glands Lecture 7: Disorders of Thyroid (Pathophysiology of Thyroid diseases) Problem Based Learning (PBL) PBL 1: Mr. Uthai Jaidee (Meeting 1) June 8th, 2009 3 13.00-14.00 14.00-15.00 Lecture 1: Fundamental concept of endocrinology Lecture 8: Thyroid hormone & Antithyroid drugs Lecture 9: Anatomy, Histology and physiology of Adrenal gland 7 Week Date/Time 8.00-9.00 9.00-10.00 10.00-11.00 11.00-12.00 June 15th, 2009 4 June 17th, 2009 June 24th, 2009 6 15.00-16.00 Problem Based Learning (PBL) PBL 1: Mr. Uthai Jaidee (Meeting 2) Lecture 12: Disorders of the Endocrine Pancreas (Pathophysiology of Selected Endocrine Pancreatic Disorders) Lecture 13:Insulin and Glucagon Lecture 14:Oral antidiabetic Agents June 29th, 2009 July 1st , 2009 14.00-15.00 Lecture 11:Anatomy, Histology and physiology of endocrine pancrease Self-Directed Learning 1 (SDL 1): Disorder of endocrine tumor June 22nd, 2009 5 13.00-14.00 Lecture 10: Disorders of Adrenal gland (Pathophysiology of Adrenocortical Disorders) Self-Directed Learning 2 (SDL 2): Anti-obesity drugs 8 Week 7 Date/Time 8.00-9.00 9.00-10.00 10.00-11.00 11.00-12.00 13.00-14.00 Lecture 15: Principles of reproductive system and sex hormone July 6th , 2009 July 6th , 2009 July 15 , 2009 th Lecture 18: The Testis (Androgens & Anabolic Steroids, Antiandrogens, & Male Contraception) Lecture 19: Anatomy and physiology : Endocrinology of Female Reproduction July 20th , 2009 9 July 22nd , 2009 16.00-17.00 Lecture 17: Disorder of Male Reproductive system (Pathophysiology of male Reproductive Tract Disorders) Holiday 1: Buddhist Lent Day Problem Based Learning (PBL) PBL 2: Ms. Chadaporn Natong (Meeting 1) July 13th , 2009 8 14.00-15.00 15.00-16.00 Lecture 16: Anatomy, Histology and physiology : Endocrinology of Male Reproduction Lecture 20: Disorder of female Reproductive system 9 Week 10 Date/Time 8.00-9.00 9.00-10.00 10.00-11.00 11.00-12.00 July 27th , 2009 July 29th , 2009 Self-Directed Learning 3 (SDL 3): Erectile dysfunction August 3rd,2009 11 August 5th,2009 12 August 10th,2009 August 12th,2009 13.00-14.00 14.00-15.00 15.00-16.00 Lecture 21: The Ovary (Estrogens, Progestins, Other Ovarian Hormones, Oral Contraceptives, Inhibitors & Antagonists, & Ovulation-Inducing Agents) Lecture 22: Disorder of lipid metabolism and obesity Lecture 23: Rational Prescribing & Prescription Writing Problem Based Learning (PBL) PBL 2: Ms. Chadaporn Natong (Meeting 2) Demonstrate Laboratory : microanatomy and Histology of Endocrine system Lecture 24: Toxic response of endocrine system Holiday 2: H.M. The Queen, s Birthday 10 Lecture Examination Lecture Examination 1 Lecture Examination 2 Lecture Examination 3 Examination Content Date Lecture 1-10 ( 11 hr.) June 24nd , 2009 Lecture 11-18 (11 hr.) July 22th , 2009 Lecture 18-24 (12 hr.) August 21th , 2009 Time 17.00-19.00 17.00-19.00 16.00-18.00 Room No. HMS-317 Examination Lecture Examination 1 (HMS-317): Lecture Content No. 1. Fundamental concept of endocrinology 2. Anatomy, Histology and physiology of Hypothalamus & Pituitary gland 3. Disorders of Hypothalamus & Pituitary gland 4. Hypothalamic & Pituitary Hormones 5 Anatomy, Histology and physiology of Thyroid & Parathyroid Glands 6. Calcium Homeostasis 7. Disorders of Thyroid (Pathophysiology of Thyroid diseases) 8 Thyroid hormone & Antithyroid drugs 9. Anatomy, Histology and physiology of Adrenal gland 10. Disorders of Adrenal gland (Pathophysiology of Adrenocortical Disorders) Total Hour Lecturer 2 1 Taweeporn Rapheeporn 1 1 1 Taweeporn Attarat Rapheeporn 1 1 1 1 1 Taweeporn Taweeporn Apichaya Thirayudh Thirayudh 11 11 Lecture Examination 2 (HMS-317): Lecture Content No. 11. Anatomy, Histology and physiology of endocrine pancrease 12. Disorders of the Endocrine Pancreas (Pathophysiology of Selected Endocrine Pancreatic Disorders) 13. Insulin and Glucagon 14. Oral antidiabetic Agents 15. Principles of reproductive system and sex hormone 16. Anatomy, Histology and physiology : Endocrinology of Male Reproduction 17. Disorder of Male Reproductive system (Pathophysiology of male Reproductive Tract Disorders) 18. The Testis (Androgens & Anabolic Steroids, Antiandrogens, & Male Contraception) Total Lecture Examination 3 (HMS-317): Lecture Content No. 19. Anatomy and physiology : Endocrinology of Female Reproduction 20. Disorder of female Reproductive system 21. The Ovary (Estrogens, Progestins, Other Ovarian Hormones, Oral Contraceptives, Inhibitors & Antagonists, & Ovulation-Inducing Agents) 22. Disorder of lipid metabolism and obesity 23. Rational Prescribing & Prescription Writing 24. Toxic response of endocrine system Total Hour Lecturer 1 1 Rapheeporn Rapheeporn 1 2 1 2 Wichai Wichai Rapheeporn Chadayu 1 Thirayudh 2 Attarat 11 Hour Lecturer 2 Thawatchai 2 3 Kitpramuk Wichai 1 1 3 12 Voranunt Wichai Thirayudh 12