University of Maryland, College Park Maryland Institute for Applied Environmental Health MIEH 600 - Foundations of Environmental Health Summer Session I 2009 Version 4: June 15, 2009 Instructor: Betty J Dabney, PhD Office/Phone: SPH 2310 / 301-405-6583 OFFICE HOURS Mon & Wed 5:00 – 6:00 p.m. and by appointment Email: bdabney@umd.edu Semester: Summer I 2009 June 1 - July 11 Classroom/Time: SPH 0303 / Mon Wed 6:00 – 9:45 p.m. Required Textbook & Other Readings Required Robert H. Friis: Essentials of Environmental Health. Sudbury, MA: Jones and Bartlett, 2007. Paper. ISBN 0-7637-4762-9 Readings from journals on Blackboard http://elms.umd.edu, as well as other assignments Recommended Course Description Course Objectives Rachel Carson: Silent Spring. Mariner Books; 40th Anniversary edition, 2002. Paperback, 400 pp, ISBN: 0618249060 Al Gore: An Inconvenient Truth: The Planetary Emergency of Global Warming and What We Can Do About It (Paperback). Rodale Books, 2006, 328 pp, ISBN 1594865671. Alternate: DVD. Environmental health is the study of the interactions between humankind and our environment. This course is based on the idea that our total environment – that is, everything we interact with in the course of living – plays a role in determining our state of health. We will discuss the major principles, methods and issues of environmental health. The first half of the course will cover various environmental media, common contaminants in them, and current environmental issues. The second half will deal with some major environmental diseases. We will analyze real-world examples of past and current significance, and effective approaches to abatement and prevention. Student teams will prepare and present a white paper on a pre-approved environmental health topic of their choice. This paper will include definition of the environmental hazard(s), evaluation of exposures, related health outcome(s), social and policy implications, and recommendations for future research and/or policy on the topic. Team members will have observations and interviews with community members and government officials as part of the project. At the conclusion of this course, the student will be able to: 1. Discuss the role of environmental health as part of overall public health. 2. Interpret major problems in environmental health in the world, the U.S. and Maryland. 3. Access and reference major sources of information in environmental health. 4. Identify contaminants in different environmental media and explain how they may interact with each other. 5. Discuss the known health effects of major environmental contaminants. 6. Analyze environmental health policies and practices from the standpoint of sustainability. 7. Articulate how environmental pollutants are regulated and prevented in the U.S. and abroad. Learning Objectives Course Organization Prerequisites: Course Requirements This course relates to the following Learning Objective of the Environmental Health Sciences M.P.H. curriculum: 1. Students shall be able to demonstrate in-depth knowledge of major environmental risk factors and their associated adverse human health outcomes (i.e. illnesses, conditions and diseases). Course Organization: Classes will consist of discussion and lectures by faculty and guest speakers working in the field of environmental health. Students are expected to complete the assigned readings prior to the class for which they are assigned and be prepared to discuss those readings during class—this includes the class text reading and journal articles. The instructor welcomes meetings with students outside of class to discuss questions and environmental health, as well as to gain more insight about the material presented in class. Students may e-mail, call, or ask during class for an appointment. Please be reminded, however, that the class will be taught during class time only. Material will not be presented again on a one-on-one basis at other times. Excused absences will be granted for unusual circumstances when arranged with the instructor. Excessive lateness or absence from class is disruptive to the class and your learning. Students who miss class are responsible for obtaining notes and hand-outs from other students. The instructor will not meet with you to retrieve copies of hand-outs from past lectures except in pre-arranged and special circumstances. Prerequisites: Graduate status. Undergraduate courses in chemistry, biology, and/or health are desirable. Examinations: There will be a midterm exam in the first hour of Class 9. There will also be a final exam at the scheduled time during finals week. The midterm exam will count 25% of your grade, and the final exam will count 25%, for a total of 50%. The final exam will not be cumulative, but may draw on principles learned in the first half of the course. Critiques of Peer-Reviewed Studies: In alphabetical rotation, each student will find an original study (not review article) in a peer-reviewed journal, and develop a critique for oral and written presentation. The study should be on a topic related to that class session. The critiques shall consist of the following sections, described in your own words: The general subject area of the study; Any pertinent historical information about the topic What the researchers were trying to show: the research hypothesis Type of study design (case-control, cross-sectional, cohort – the paper should state this) Description of study group vs. comparison group How exposure was determined (ambient or personal monitoring, biomonitoring, ecological study – no individual exposure data, stratification of relative exposures – high, med, low, etc.) Results Authors’ conclusions Strengths and weaknesses of the study (authors will often include this in their discussion) Any suggestions for further studies Written critiques will be approximately 2 pages in length. In addition, each student will describe the study to the class in no more than 5 minutes. Students will be graded on both written and oral presentations. The critiques will count 10% of the course grade. Project: Each student will participate in a team to study a current problem in environmental health involving our community, region, state, or country. This project should not duplicate work for other courses. By Class 3, your team must select a topic, which should be approved by the instructor. By Class 7, provide a one page written summary and rationale for your topic. By Class 9, you must provide an outline and preliminary bibliography of your paper. A minimum of 20 scholarly references besides the textbook are required. Choose subject areas that relate to the relationship between environmental hazards, exposures, and health outcomes or effects. Many of the journals are available in our online library, and others are available from Inter-Library Loan. Correct spelling, proper grammar and style, and flowing syntax should be used in your paper. Seek help from campus resources to strengthen and enhance your written communication skills. Each team may decide how to divide up the work and sub-topics. Part of the project should involve going out into the community and interviewing residents and/or community leaders and lawmakers about the issue. Team members will prepare a written and oral report on the project. The project will be worth 25% of your grade. Each team will give a summary presentation of the term project during class. The format for the paper should be appropriate for the topic. A suggested outline is: Introduction and Statement of the Problem History of the Problem Summary of Findings of Major Studies or Developments Strengths and Weaknesses of Studies Current Status and Data Gaps Conclusions and Recommendations for Research and/or Policy Changes. The presentation should summarize the nature of the project, the methods and approaches, the findings and the meaning or significance of the findings, and recommendations for future action. The team presentation will count 5% of the course grade for each of the members of the team. The written team report will be due by midnight on July 6, the day of the presentations. Class Participation: Maintaining an active presence in class will prepare you to learn the content and to be successful in your class assignments. This includes participation in class discussions and exercises, and conscientious performance as a member of a group for your project. Class participation will count 10% toward the final course grade. Course Policies: In the event that the University is closed for an emergency or extended period of time, the instructor will communicate to students regarding schedule adjustments, including rescheduling of examinations and assignments due to inclement weather and campus emergencies. Official closures and delays are announced on the campus website (http://www.umd.edu) and snow phone line (301-405-SNOW), as well as local radio and TV stations. LATE WORK AND MAKE UP TESTS: All work is due when assigned. Current events will be submitted on the Class Wiki in Blackboard for the appropriate week. Term papers should be submitted in electronic format as e-mail attachments. Any work not completed and handed in at the beginning of class on the due date will receive a reduction of one letter grade. Work not handed in by 5pm the following day will receive an additional letter grade reduction. Work will not be accepted beyond this point except in extreme circumstance approved by your instructor. You must prearrange with the instructor to miss a class deadline. There are no make-up tests unless they are prearranged. SPECIAL NEEDS: If you follow religious observances, have a documented disability, or have some other important commitments for which you need special academic accommodations, please contact the instructor in advance. Accommodations must be prearranged. If you have a documented disability and wish to discuss academic accommodations for test taking or other needs, you will need documentation from Disability Support Service (301-314-7682). If you are ill or encountering personal difficulties, please let the instructor know as soon as possible. You can also contact Learning Assistance Services (301-314-7693) and/ or the Counseling Center (301-314-7651) for assistance. RELIGIOUS OBSERVANCES: The University System of Maryland policy provides that students should not be penalized because of observances of their religious beliefs; students shall be given an opportunity, whenever feasible, to make up within a reasonable time any academic assignment that is missed due to individual participation in religious observances. It is the student’s responsibility to inform the instructor in advance of any intended absences for religious observance. ACADEMIC INTEGRITY: The University's code of academic integrity is designed to ensure that the principle of academic honesty is upheld. Any of the following acts, when committed by a student, constitutes academic dishonesty: CHEATING: intentionally using or attempting to use unauthorized materials, information, or study aids in an academic exercise. FABRICATION: intentional and unauthorized falsification or invention of any information or citation in an academic exercise. FACILITATING ACADEMIC DISHONESTY: intentionally or knowingly helping or attempting to help another to violate any provision of this code. PLAGIARISM: intentionally or knowingly representing the words or ideas of another as one's own in any academic exercise. For more information see: http://www.studenthonorcouncil.umd.edu/code.html. The University of Maryland, College Park has a nationally recognized Code of Academic Integrity, administered by the Student Honor Council. This Code sets standards for academic integrity at Maryland for all undergraduate and graduate students. As a student you are responsible for upholding these standards for this course. It is very important for you to be aware of the consequences of cheating, fabrication, facilitation, and plagiarism. To further exhibit your commitment to academic integrity, remember to sign the Honor Pledge on all examinations and assignments: "I pledge on my honor that I have not given or received any unauthorized assistance on this examination (assignment).” Bibliography (May also be used in paper) Centers for Disease Control and Prevention: http://www.cdc.gov U.S. Environmental Protection Agency: http://www.epa.gov World Health Organization: http://www.who.int Maryland Department of Health and Mental Hygiene: http://www.dhmh.state.md.us Maryland Department of the Environment: http://www.mde.state.md.us National Library of Medicine PubMed search engine for the world’s medical literature: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed (If you search through UM Library’s Research Port, you will get links to more full-text articles.) Centers for Disease Control and Prevention, National Center for Health Statistics. Health, United States, 2006 With Chartbook on Trends in the Health of Americans With Special Feature on Pain. http://www.cdc.gov/nchs/data/hus/hus06.pdf Centers for Disease Control and Prevention. Third National Report on Human Exposure to Environmental Chemicals, 2005. http://www.cdc.gov/exposurereport/ Environmental Health Perspectives 109 Supplement 2, 2001: Human Health Consequences of Climate Change and Variability for the United States. http://www.ehponline.org/docs/2001/suppl-2/toc.html . Robert H. Friis: Essentials of Environmental Health. Jones & Bartlett Publishers; 1st edition, 2006. 416 pp., Paperback. ISBN 0763747629 Howard Frumkin (Editor): Environmental Health: From Global to Local. Jossey-Bass (Wiley), 2005, 1108 pages, $74.00. Hardcover. ISBN 0787973831 Gary S. Moore (Editor): Living with the Earth: Concepts in Environmental Health Science, Second Edition. CRC Press, 2002, 624 pp, Hardcover. ISBN 1566705851 Jeanne Mager Stellman (Editor): Encyclopaedia of Occupational Health and Safety, Fourth Edition (4 Volumes). International Labour Office, Geneva, 199, 1000 pp, Hardcover. ISBN-10: 9221092038 ISBN-13: 978-9221092032 World Health Organization: Preventing disease through healthy environments: Towards an estimate of the environmental burden of disease. Geneva, 2006. ISBN 92 4 159382 2 http://www.who.int/quantifying_ehimpacts/publications/preventingdisease.pdf American Lung Association: Secondhand Smoke Fact Sheet http://www.lungusa.org/site/pp.asp?c=dvLUK9O0E&b=35422 American Thoracic Society. Workshop on Lung Disease and the Environment - Where Do We Go from Here? Am J Respir Crit Care Med Vol 168. pp 250–254, 2003. Centers for Disease Control and Prevention Agency for Toxic Substances and Disease Registry. Toxicological Profile for Asbestos, 2001. http://www.atsdr.cdc.gov/toxprofiles/tp61.pdf Ashford NA. Implementing the Precautionary Principle: incorporating science, technology, fairness, and accountability in environmental, health, and safety decisions. Int J Occup Med Environ Health. 2004;17(1):59-67. Atlas MK. Safe and sorry: risk, environmental equity, and hazardous waste management facilities. Risk Anal. 2001 Oct;21(5):939-54.. Bell ML, Davis DL. Reassessment of the lethal London fog of 1952: novel indicators of acute and chronic consequences of acute exposure to air pollution. Environ Health Perspect. 2001 Jun;109 Suppl 3:389-94. http://www.ehponline.org/members/2001/suppl-3/pdf/bell.pdf Bernard SM, Samet JM, Grambsch A, Ebi KL, Romieu I. The potential impacts of climate variability and change on air pollution-related health effects in the United States. Environ Health Perspect. 2001 May;109 Suppl 2:199-209. http://www.ehponline.org/docs/2001/suppl-2/199-209bernard/bernard.pdf Blane D. Social determinants of health--socioeconomic status, social class, and ethnicity. Am J Public Health. 1995 Jul;85(7):903-5. Borchers AT, Chang C, Keen CL, Gershwin ME. Airborne environmental injuries and human health. Clin Rev Allergy Immunol. 2006 Aug;31(1):1-101. Bourdeau P. The man-nature relationship and environmental ethics. J Environ Radioact. 2004;72(12):9-15. Bower JJ, Shi X. Environmental health research in the post-genome era: new fields, new challenges, and new opportunities. J Toxicol Environ Health B Crit Rev. 2005 Mar-Apr;8(2):71-94. Brent RL, Weitzman M. The current state of knowledge about the effects, risks, and science of children's environmental exposures. Pediatrics. 2004 Apr;113(4 Suppl):1158-66. Breysse PN, Buckley TJ, Williams D, Beck CM, Jo SJ, Merriman B, Kanchanaraksa S, Swartz LJ, Callahan KA, Butz AM, Rand CS, Diette GB, Krishnan JA, Moseley AM, Curtin-Brosnan J, Durkin NB, Eggleston PA. Indoor exposures to air pollutants and allergens in the homes of asthmatic children in inner-city Baltimore. Environ Res. 2005 Jun;98(2):167-76. Bridges J. Human health and environmental risk assessment: the need for a more harmonised and integrated approach. Chemosphere. 2003 Sep;52(9):1347-51. Briggs D. Environmental pollution and the global burden of disease. Br Med Bull. 2003; 68:1-24. Brody JG, Tickner J, Rudel RA. Community-initiated breast cancer and environment studies and the precautionary principle. Environ Health Perspect. 2005 Aug;113(8):920-5. Brownson RC, Haire-Joshu D, Luke DA. Shaping the context of health: a review of environmental and policy approaches in the prevention of chronic diseases. Annu Brody JG, Tickner J, Rudel RA. Community-initiated breast cancer and environment studies and the precautionary principle. Environ Health Perspect. 2005 Aug;113(8):920-5. Rev Public Health. 2006;27:341-70. Brulle RJ, Pellow DN. Environmental justice: human health and environmental inequalities. Annu Rev Public Health. 2006;27:103-24. Boffetta P. Human cancer from environmental pollutants: the epidemiological evidence. Mutat Res. 2006 Sep 28;608(2):157-62. Clarkson TW, Magos L. The toxicology of mercury and its chemical compounds. Crit Rev Toxicol. 2006 Sep;36(8):609-62. Cooper RL, Kavlock RJ. Endocrine disruptors and reproductive development: a weight-of-evidence overview. J Endocrinol. 1997 Feb;152(2):159-66. Cummins SK, Jackson RJ. The built environment and children's health. Pediatr Clin North Am. 2001 Oct;48(5):1241-52, x. Daughton CG. Environmental stewardship and drugs as pollutants. Lancet. 2002 Oct 5;360(9339):1035-6. de Rosa CT, El-Masri HA, Pohl H, Cibulas W, Mumtaz MM. Implications of chemical mixtures in public health practice. J Toxicol Environ Health B Crit Rev. 2004 Sep-Oct;7(5):339-50. Dhala A, Pinsker K, Prezant DJ. Respiratory health consequences of environmental tobacco smoke. Clin Occup Environ Med. 2006;5(1):139-56, x. Dolk H, Vrijheid M. The impact of environmental pollution on congenital anomalies. Br Med Bull. 2003;68:25-45. Ezzati M, Utzinger J, Cairncross S, Cohen AJ, Singer BH. Environmental risks in the developing world: exposure indicators for evaluating interventions, programmes, and policies. J Epidemiol Community Health. 2005 Jan;59(1):15-22. Forget G, Lebel J. An ecosystem approach to human health. Int J Occup Environ Health. 2001 AprJun;7(2 Suppl):S3-38. Frumkin H. Health, equity, and the built environment. Environ Health Perspect. 2005 May;113(5):A290-1. Galea S, Vlahov D. Urban health: evidence, challenges, and directions. Annu Rev Public Health. 2005;26:341-65. Gee GC, Payne-Sturges DC. Environmental health disparities: a framework integrating psychosocial and environmental concepts. Environ Health Perspect. 2004 Dec;112(17):1645-53. Goldstein BD. Advances in risk assessment and communication. Annu Rev Public Health. 2005;26:141-63. Goldstein BD, Carruth RS. Implications of the Precautionary Principle: is it a threat to science? Int J Occup Med Environ Health. 2004;17(1):153-61. Grandjean P. Implications of the precautionary principle for primary prevention and research. Annu Rev Public Health. 2004;25:199-223. Ham SA, Levin S, Zlot AI, Andrews RR, Miles R. Ranking of cities according to public health criteria: pitfalls and opportunities. Am J Public Health. 2004 Apr;94(4):546-9. Jones J. Mother nature's disasters and their health effects: a literature review. Nurs Forum. 2006 AprJun;41(2):78-87 Keiser J, Singer BH, Utzinger J. Reducing the burden of malaria in different eco-epidemiological settings with environmental management: a systematic review. Lancet Infect Dis. 2005 Nov;5(11):695708. Kelada SN, Eaton DL, Wang SS, Rothman NR, Khoury MJ. The role of genetic polymorphisms in environmental health. Environ Health Perspect. 2003 Jun;111(8):1055-64. Kistemann T, Dangendorf F, Schweikart J. New perspectives on the use of Geographical Information Systems (GIS) in environmental health sciences. Int J Hyg Environ Health. 2002 Apr;205(3):169-81 Krieger J, Higgins DL. Housing and health: time again for public health action. Am J Public Health. 2002 May;92(5):758-68. Kulshrestha M, Mittal AK. Diseases associated with poor water and sanitation: hazards, prevention, and solutions. Rev Environ Health. 2003 Jan-Mar;18(1):33-50. LaKind JS, Amina Wilkins A, Berlin CM Jr. Environmental chemicals in human milk: a review of levels, infant exposures and health, and guidance for future research. Toxicol Appl Pharmacol. 2004 Jul 15;198(2):184-208. Landrigan PJ. Children's environmental health. Lessons from the past and prospects for the future. Pediatr Clin North Am. 2001 Oct;48(5):1319-30. Lawler CP, Croen LA, Grether JK, Van de Lawler CP, Croen LA, Grether JK, Van de Water J. Identifying environmental contributions to autism: provocative clues and false leads. Ment Retard Dev Disabil Res Rev. 2004;10(4):292-302.Water J. Identifying environmental contributions to autism: provocative clues and false leads. Ment Retard Dev Disabil Res Rev. 2004;10(4):292-302. Lima AA, Guerrant RL. Strategies to reduce the devastating costs of early childhood diarrhea and its potential long-term impact: imperatives that we can no longer afford to ignore. Clin Infect Dis. 2004 Jun 1;38(11):1552-4. London L, Kisting S. Ethical concerns in international occupational health and safety. Occup Med. 2002 Oct-Dec;17(4):587-600. Mac Kenzie WR, Hoxie NJ, Proctor ME et al: A Massive Outbreak in Milwaukee of Cryptosporidium Infection Transmitted through the Public Water Supply. New England Journal of Medicine 1994 July 21; 331(3): 161-167. Magos L, Clarkson TW. Overview of the clinical toxicity of mercury. Ann Clin Biochem. 2006 Jul;43(Pt 4):257-68. Martuzzi M, Bertollini R. The Precautionary Principle, science and human health protection. Int J Occup Med Environ Health. 2004;17(1):43-6. Mastin JP. Environmental cardiovascular disease. Cardiovasc Toxicol. 2005;5(2):91-4. Morello-Frosch R, Shenassa ED. The environmental "riskscape" and social inequality: implications for explaining maternal and child health disparities. Environ Health Perspect. 2006 Aug;114(8):1150-3. Morgan WJ, Crain EF, Gruchalla RS, O'Connor GT, Kattan M, Evans R 3rd, Stout J, Malindzak G, Smartt E, Plaut M, Walter M, Vaughn B, Mitchell H; Inner-City Asthma Study Group. Results of a home-based environmental intervention among urban children with asthma. N Engl J Med. 2004 Sep 9;351(11):1068-80. (Available through UM Research Port) Moya J, Bearer CF, Etzel RA. Children's behavior and physiology and how it affects exposure to environmental contaminants. Pediatrics. 2004 Apr;113(4 Suppl):996-1006. http://pediatrics.aappublications.org/cgi/reprint/113/4/S1/996 Ng JC, Wang J, Shraim A. A global health problem caused by arsenic from natural sources. Chemosphere. 2003 Sep;52(9):1353-9. Noji EK. Public health in the aftermath of disasters. BMJ. 2005 Jun 11;330(7504):1379-81. Omenn GS. The crucial role of the public health sciences in the postgenomic era. Genet Med. 2002 Nov-Dec;4(6 Suppl):21S-26S. Ozakinci G, Hallman WK, Kipen HM. Persistence of symptoms in veterans of the First Gulf War: 5year follow-up. Environ Health Perspect. 2006 Oct;114(10):1553-7. http://www.ehponline.org/members/2006/9251/9251.pdf Patz JA, Kovats RS. Hotspots in climate change and human health. BMJ. 2002 Nov 9;325(7372):10948. Paustenbach D, Galbraith D. Biomonitoring and biomarkers: exposure assessment will never be the same. Environ Health Perspect. 2006 Aug;114(8):1143-9. http://www.ehponline.org/members/2006/8755/8755.pdf Rushton L. Health hazards and waste management. Br Med Bull. 2003;68:183-97. Sharp RR. Ethical issues in environmental health research. Environ Health Perspect. 2003 Nov;111(14):1786-8. Silbergeld EK. Preventing lead poisoning in children. Annu Rev Public Health. 1997;18:187-210. Suk WA, Olden K, Yang RS. Chemical mixtures research: significance and future perspectives. Environ Health Perspect. 2002 Dec;110 Suppl 6:891-2. Sundell J. On the history of indoor air quality and health. Indoor Air. 2004;14 Suppl 7:51-8. Thier R, Bruning T, Roos PH, Rihs HP, Golka K, Ko Y, Bolt HM. Markers of genetic susceptibility in human environmental hygiene and toxicology: the role of selected CYP, NAT and GST genes. Int J Hyg Environ Health. 2003 Jun;206(3):149-71. U.S. Surgeon General: The health consequences of involuntary exposure to tobacco smoke : a report of the Surgeon General. – [Atlanta, Ga.] : U.S. Dept. of Health and Human Services, Centers for Disease Control and Prevention, Coordinating Center for Health Promotion, National Center for Chronic Disease Prevention and Health Promotion, Office on Smoking and Health, [2006]. Chapter 1 Introduction, Summary, and Conclusions. Chapter 1: Introduction, Summary and Conclusions. http://www.surgeongeneral.gov/library/secondhandsmoke/report/chapter1.pdf . Walker-Bone K, Cooper C. Hard work never hurt anyone--or did it? A review of occupational associations with soft tissue musculoskeletal disorders of the neck and upper limb. Ann Rheum Dis. 2005 Aug;64(8):1112-7. Weber RF, Pierik FH, Dohle GR, Burdorf A. Environmental influences on male reproduction. BJU Int. 2002 Jan;89(2):143-8. Woodruff TJ, Axelrad DA, Kyle AD, Nweke O, Miller GG, Hurley BJ. Trends in environmentally related childhood illnesses. Pediatrics. 2004 Apr;113(4 Suppl):1133-40. Zhang J, Smith KR. Indoor air pollution: a global health concern. Br Med Bull. 2003;68:209-25. You may use websites with proper documentation in your term project, but be sure to examine the reliability of the source. Ask yourself: Is there any bias or personal agenda that the author(s) or webmaster(s) might have with regard to the issue under discussion? U.S. government agencies’ websites may be especially useful Some Useful Journals in Environmental Health American Journal of Epidemiology American Journal of Public Health Annual Review of Pharmacology and Toxicology Archives of Diseases of Childhood Archives of Environmental Health Archives of Pediatrics and Adolescent Medicine Archives of Toxicology Atmospheric Environment ATSDR Toxicological Profiles Biology of Metals Birth Defects Research British Medical Journal Bulletin of Environmental Contamination and Toxicology Cardiovascular Toxicology Cell Biology and Toxicology Chemical Research in Toxicology CRC Critical Reviews in Toxicology Critical Reviews in Toxicology Developments in Toxicology and Environmental Science Ecotoxicology (London, England) Ecotoxicology and Environmental Safety Environment International Environmental Health Perspectives Environmental Research Environmental Science & Technology Environmental Sciences Environmental Toxicology Environmental Toxicology and Chemistry / SETAC. Environmental Toxicology and Pharmacology Epidemiology European Journal of Toxicology. Food and Chemical Toxicology Food and Cosmetics Toxicology Food Protection Trends Fundamental and Applied Toxicology Ground Water Human and Experimental Toxicology Human Toxicology IARC Monographs on the Evaluation of Carcinogenic Risks to Humans Immunopharmacology and Immunotoxicology In Vitro & Molecular Toxicology Inhalation Toxicology International Journal of Environmental Analytical Chemistry International Journal of Epidemiology International Journal of Hygiene and Environmental Health International Journal of Toxicology Journal of the American Medical Association (JAMA) Journal - American Water Works Association Journal of Analytical Toxicology Journal of Applied Toxicology : JAT Journal of Biochemical and Molecular Toxicology Journal of Biochemical Toxicology Journal of Environmental Pathology and Toxicology Journal of Environmental Science and Health Journal of the National Cancer Institute Journal of Occupational and Environmental Medicine Journal of Pharmacological and Toxicological Methods The Journal of Toxicological Xciences Journal of Toxicology and Environmental Health Lancet Marine Environmental Research Medicine and Health Molecular Toxicology Morbidity and Mortality Weekly Report (CDC) Mutation Research National Toxicology Program Technical Report Series Neurobehavioral Toxicology Neurobehavioral Toxicology and Teratology Neurotoxicology Neurotoxicology and Teratology New England Journal of Medicine Occupational and Environmental Medicine Pediatrics Pharmacology & Toxicology Progress in Chemical Toxicology Public Health Reports Regulatory Toxicology and Pharmacology : RTP Reproductive Toxicology (Elmsford, N.Y.) Reviews of Environmental Contamination and Toxicology Risk Analysis Teratogenesis, Carcinogenesis, and Mutagenesis Toxic Substance Mechanisms Toxicity Report Series Toxicological Reviews Toxicology Toxicology and Applied Pharmacology Toxicology and Industrial Health Toxicology in vitro Toxicology Letters. Toxicon : Official Journal of the International Society on Toxicology Veterinary and human toxicology World Health Organization Environmental Health Criteria Xenobiotica: The Fate of Foreign Compounds in Biological Systems Class Schedule Class One June 1 Major Problems in Our Environment Introduction and Scope of Environmental Health Environmental Media: Their Behavior, Contaminants and Diseases Climate Change and Update to “An Inconvenient Truth” and “Silent Spring” Sustainability Welcome and introductions Review syllabus and course requirements and policies How to use the UMCP Library and PubMed Definition of our environment / water cycle / food chain Breakout Groups: Global, national, local and personal environmental issues Scope of environmental health in theory and in practice Relationship of environmental health to other areas of public health The role of environment in the burden of disease The environmental health paradigm: hazard - exposure - effect - disease outcome Climate Change Update to “An Inconvenient Truth” and “Silent Spring” Discussion: Are we as a global society living sustainably? Readings: Friis Chapter 1 IPCC 4th Assessment Report, Chapter 8: Human Health. (Confalonieri, U., B. Menne, R. Akhtar, K.L. Ebi, M. Hauengue, R.S. Kovats, B. Revich and A. Woodward, 2007: Human health. Climate Change 2007: Impacts, Adaptation and Vulnerability. Contribution of Working Group II to the Fourth Assessment Report of theIntergovernmental Panel on Climate Change, M.L. Parry, O.F. Canziani, J.P. Palutikof, P.J. van der Linden and C.E. Hanson, Eds., Cambridge University Press, Cambridge, UK, 391-431.) http://www.ipcc.ch/pdf/assessment-report/ar4/wg2/ar4-wg2-chapter8.pdf Class Two June 3 Introduction to Environmental Epidemiology and Toxicology Environmental epidemiology: the beginnings of environmental health Environmental epidemiology tools and study designs Criteria of causality Toxicology 101: Definition, types of exposures, dose-response curves Introduction to human exposure assessment The problem of mixed exposures o Case Study: The Gulf War Syndrome: Real or Imagined? Introduction to human risk assessment Environmental health impact assessments In class: Selecting teams and discussion of possible ideas for term projects No student critiques for this class. Readings: Friis Chapters 2 & 3 Class Three June 8 Optional: Post a current events story or peer-reviewed study on environmental epidemiology, toxicology, risk assessment or health impact assessment in the course wiki on Blackboard IN YOUR OWN WORDS, and be prepared to discuss briefly in class. (0.02 point credit) Toxicology 101 Continued: Major Classes of Toxic Substances and Their Effects Metals Case Study: Children’s Lead Poisoning in Baltimore City Case Study: Arsenic in West Bengal and Bangladesh Organic Chemicals Case Study: Air Toxics in the U.S. and Maryland Case Study: The Tragedy of Bhopal Pesticides Case Study: Agent Orange and Operation Ranch Hand Viet Nam Veterans Student Presentations: Find and critique a peer-reviewed study relating to a topic in this class: Barbara Zappe In class: Finalize topics for term project. Reading: Friis Chapters 5, 6, 7, 8 (skim all) Class Four June 10 Optional: Current events story or peer-reviewed paper about metals, organic chemicals, or pesticides Water and Waterborne Diseases Review of the hydrologic cycle Global distribution and sources of water; issues for sustainability Major water contaminants and their health effects Regulation of water contaminants Sources of drinking water Drinking water treatment Waste water treatment Recreational water and beaches Case Study: Infantile Diarrhea in Developing Countries Case Study: Cryptospiridosis in Milwaukee, Wisconsin Case Study: Exxon Valdez Oil Spill Case Study: Cholera and Climate Change Case Study: The Death of Chesapeake Bay Student Presentations: Find and critique a peer-reviewed study relating to a topic in this class: Katherine Michel Readings: Friis Chapter 9 Assignment Optional: Current events story or peer-reviewed paper about water, water contaminants, or water borne disease. Class Five June 15 Soil, Waste Water, Municipal Waste, Hazardous Waste and Associated Diseases Our wasteful society Methods for reducing waste: source reduction, recycling, co-generation Solid Waste and Landfills: hazardous and municipal Regulation of waste disposal Hazards of poorly designed waste disposal sites and treatment Case Study: The Love Canal Case Study: Chicken farms on the Eastern Shore Waste Water Treatment Storm Water Student Presentations: Find and critique a peer-reviewed study relating to a topic in this class: Lili Huang, Armen Ghazarian Reading: Friis Chapter 12 Assignment Optional: Current events story or peer-reviewed paper about soil, waste water, municipal waste, hazardous waste or associated diseases Class Six June 17 Radiation, Temperature, Sound and Hyper/hypobaric Pressure Types of Radiation Health Effects of Radiation Case Study: Tanning Case Study: Cell phones and brain tumors Case Study: Chernobyl vs. Three Mile Island Case Study: Deafness in rock musicians Student Presentations: Find and critique a peer-reviewed study relating to a topic in this class: Reena Mathew, Anissa Marzuki Assignment: Friis Chapter 8 Continue work on term project Optional: Post and briefly discuss a current events story or peer-reviewed study on one of today’s topics. Class Seven June 22 Air Contaminants and Related Diseases Air Contaminants Acute Respiratory Diseases and Air Pollution: Myocardial Infarctions (Heart Attacks), Strokes Chronic Respiratory Diseases and Air Contaminants: Chronic Bronchitis, Asthma, COPD, Respiratory Cancers Case Study: The Great London Fog of 1952 Case Study: Environmental Tobacco Smoke Case Study: Asthma in Baltimore City Student Presentations: Find and critique a peer-reviewed study relating to a topic in this class: Brad Kerridge, Adjoa Degbo TEAMS TURN IN 1-PAGE DISCUSSION AND JUSTIFICATION OF TERM PROJECT. Readings: Friis Chapter 10 For Reference: The health consequences of involuntary exposure to tobacco smoke: a report of the Surgeon General. – [Atlanta, Ga.] : U.S. Dept. of Health and Human Services, Centers for Disease Control and Prevention, Coordinating Center for Health Promotion, National Center for Chronic Disease Prevention and Health Promotion, Office on Smoking and Health, [2006]. http://www.surgeongeneral.gov/library/secondhandsmoke/report. For reference: Borchers AT, Chang C, Keen CL, Gershwin ME. Airborne environmental injuries and human health. Clin Rev Allergy Immunol. 2006 Aug;31(1):1-101. (for reference) Assignment Teams work on bibliographies and outlines for term project. Class Eight June 24 MID-TERM EXAM (One hour) Guest Lectures FOODBORNE ILLNESS: Prof. Sam Joseph FOOD SAFETY AND REGULATION ZOONOSES AND VECTOR-BORNE DISEASES (Study Handout) Chemical and biological contaminants in food; safe handling of food Regulation of contaminants in food No assigned student critiques this week because of mid-term exam. Class discussion: Sustainability with respect to food insecurity and the world food crisis; land use and land use planning, food geography and implications for health and disease (effects of deforestation, climate change, soil depletion, unequal distribution of arable land globally). Think about these ahead of time and do some reading on your own to prepare for discussion in class. This will be a student-led discussion under the supervision of Dr. Joseph. Assignment Friis Chapter 11 Class Nine June 29 No current events this week because of mid-term exam. No student critiques this week because of mid-term – but see assignment for class discussion above. Other Determinants of Disease: Age, Race/Ethnicity, Gender, and Social, Demographic, Economic, Built Environments Special and Hypersusceptible Populations: Children, The Elderly Environmental Justice Case Study: United Church of Christ Study "Toxic Wastes and Race at Twenty 1987-2007," Student Presentations: Find and critique a peer-reviewed study relating to a topic in this class: Laura Cathcart OUTLINE AND PRELIMINARY BIBLIOGRAPHY DUE FOR PROJECT Assignment Optional: Current events story or peer-reviewed paper about one of the topics to be covered today. Class Ten July 1 Environmental Diseases: Reproductive Problems, Birth Defects, Neurodevelopmental Problems, Cancer Case study: Endocrine disruptors and pharmaceuticals in drinking water Case study: The rise in autism spectrum disorders – real or artifact? Student Presentations: Find and critique a peer-reviewed study relating to a topic in this class: Margaret Amankwa-Sakyim, AyokorAkingbade Assignment Optional: Current events story or peer-reviewed paper about environmental reproductive problems and/or birth defects. Class Eleven July 6 The Workplace as a Special Environment Approaches to Characterizing, Minimizing and Preventing Risk of Environmental Diseases Regulating Environmental and Occupational Exposures Environmental Health Ethics Case study: Child Labor and Off-shore Sweatshops Case Study: Migrant Workers No assigned student critiques this week because of term project presentations. TEAM PRESENTATIONS OF TERM PROJECTS Reports of term projects due at midnight. Readings: Friis Chapters 13, 4 Assignment Optional: Critique a current events story or peer-reviewed paper about occupational health, an environmental intervention and/or policy that was effective or not, or environmental health ethics. Class Twelve July 8 Evaluation Assignment FINAL EXAM (Non-cumulative) 2 hours Grading Weight Number Grade 96- >100% Midterm 25% 93-95% 90-92% Paper 25% 86-89% Team Presentation of Term Project 5% 83-85% 80-82% Final Exam 25% 76-79% Critiques of published studies 10% 73-75% 70-72% Class Participation 10% 66-69% 63-65% Each current event report will count 0.02 60-62% percentage point on the course grade, for a <60% total of 10 weeks or 2 possible points. Exams may also have extra-credit questions. Letter Grade A+ A AB+ B BC+ C CD+ D DF