Pedigree and Punnett Square worksheet
On a blank sheet of paper, draw the pedigree for the people described
below. You will probably want to put the paper sideways (landscape.)
There are 29 people in 4 generations.
Generation I: people 1-8. 1 mates with 2; 3 mates with 4; 5 mates with 6;
7 mates with 8
Generation II: people 9 – 19. 11 is a child from 1+2; 12 is a child from 3+4;
17 is a child from 5+6; 18 is a child from 7 + 8
Generation III: people 20 – 25: Children 20, 21, 22 from 11+12; children
23, 24, 25 from 17 + 18.
Generation IV: people 26 – 29: Children from 22 + 23.
Other info:
1+ 2 have two girls and 1 boy
3 + 4 have one girl and 2 boys
5 + 6 have one girl and 2 boys
7 + 8 have one girl and one boy
11 + 12 have two girls and one boy
17 + 18 have two boys and one girl
22 + 23 have two boys and two girls
Person
Person
Person
Person
Person
Person
Person
Person
Person
27
29
26
22
23
17
18
12
11
is
is
is
is
is
is
is
is
is
a
a
a
a
a
a
a
a
a
boy and is fully affected
girl and is fully affected
girl who died at childbirth
girl
boy
boy
girl
girl
boy
Who is affected and who is a carrier?
Well, we know that 27 and 29 are fully affected, not carriers.
We are told that 1, 10, 19, and 24 are carriers. Person 1 is a male.
We know that people 8, 27, and 29 are fully affected. Person 8 is female.
We know that neither 5 nor 6 are affected or carriers. They are totally
healthy for this trait.
People 11 and 12 look normal. They could be carriers, but are not affected.
We don’t know about other people. They could be carriers or not.
Figure out the phenotype of the people who gave birth. Siblings of people
who gave birth can not be determined for sure, but if you want to assign
them a phenotype, you may. It must follow the logic of the genetics, though.
Determine the phenotype of these people:
You should indicate: normal, carrier, or affected
1
11
2
12
3
17
4
18
5
22
6
23
7
27
8
29
On the Pedigree show the following people are dead:
9, 14, 16, 26
Using the symbols E and e to represent the trait, draw Punnett squares for
the following matings. (E is dominant, e is recessive)
Person 1 and Person 2
Person 7 and person 8
Person 11 and person 12
Person 22 and person 23
Now… in the Punnet square indicate which genotype could be for the
following people. This is not something normally done so don’t expect all of
your future Punnet squares to also have person numbers in them.
For the cross of person 1 and 2, indicate which genotype(s) person 11 has.
For the cross of person 7 and 8 indicate which genotype(s) person 18 has.
For the cross of person 11 and 12, indicate which genotype(s) person 22
has.
For the cross of person 22 and 23, indicate which genotype(s) persons 27
and 29 have.