. 2010 EPA Symposium on Ground Waterborne Infectious Disease Epidemiology, Etiologic Agents, and Indicators SECOND CIRCULAR AND INVITATION TO PARTICIPATE January 26, 27 and (28, if needed), 2010 (RE-SCHEDULED DATE) Auditorium (Seats 300) Carnegie Institution for Science 1530 P Street NW Washington, DC 20005-1910 www@ciw.edu (at Dupont Circle) Dear Potential Speaker or Participant, Please contact me by email at Berger.philip@epa.gov or telephone (202) 564-5255 if you wish to present or attend. The 2008 EPA GW Epi Symposium was oversubscribed and we had to add a third day of presentations. This year, the key speaker will present the results of the Sonoma Water Evaluation Trial (SWET), published in the American Journal of Public Health. Sonoma County Water Agency is regulated as both a ground water and as a ground water under the direct influence of surface water (GWUDI). Another key speaker will present the results of the US Geological Survey work at the Miami Dade Northwest Well-Field to establish the potential Cryptosporidium hazard using tracers. Conference registration is FREE. At this time, I have NO travel dollars available to assist speakers or participants. Invited speakers and suggested presentations include: Epidemiology and Public Health 1) Joe Eisenberg (Univ. of Michigan), The Sonoma Water Evaluation Trial: A randomized drinking water intervention trial to reduce GI illness in older adults (confirmed) 2) Speaker TBD, Health Canada, Municipal (GWUDI) drinking water as a health risk factor for people with Cryptosporidiosis (pending) 3) Speaker TBD, Brushy Creek, TX Cryptosporidium outbreak in a karst well 4) Stephen Roy, NHDEP, Bartlett, NH Giardia outbreak in a fractured bedrock well (pending) 5) Speaker TBD, Associating sporadic enteric disease with drinking water using a geographic information system, in British Columbia, Canada, 1996–2005 (pending) 6) Mark Borchardt, Update on the WAHTER study, (e.g. virus concentrations in non-chlorinated municipal drinking water: Association with community rates of acute gastrointestinal illness) (pending) 7) Gunther Craun, Floyd Frost, Lovelace Institute, Serological responses to Cryptosporidium antigens among women using riverbank-filtered water, conventionally filtered surface water and groundwater in Hungary 8) Calvin Alexander, UMinn, Plum Bottom sinkhole and the Log Den WI Norovirus outbreak (confirmed) 9) Paul Hunter, University of East Anglia, UK, Association between self-reported diarrhoeal and indicators of faecal contamination (E. coli v. Enterococci) in small rural ground water supplies,, France (confirmed) 10) Maggie Terazi, Univ. Iowa, Adenovirus14 and other epidemic adenoviruses (pending) Indicators 1) Jennifer Griffin. Johns Hopkins, Torque teno Virus: A Potential Indicator of Enteric Viruses (confirmed) 2) Carl Bolster, USDA, E. coli transport variability among 12 isolates (confirmed) 3) Jan Willem Foppen, UNESCO-IHE, Delft, E. coli transport variability among 54 isolates (confirmed) 4) Bob Renken, USGS, Cryptosporidium surrogate transport at the Miami Dade Northwest wellfield (confirmed) 5) Dave Metge, USGS, Cryptosporidium surrogate transport at the Sonoma County Russian River wellfield (confirmed) 6) Monica Emelko, University of Waterloo, Cryptosporidium removal by bank filtration at the Grand River wellfield, Kitchener-Waterloo, Ontario (confirmed) 7) Sondra Klitzke, German Environment Protection Agency (UBA), Berlin, "Facility for the Simulation of Riverbank Filtration and Slow Sand Filtration - Examples of Virus Elimination in the Subsurface under near-natural Conditions (confirmed) 8) Peter Wallis, Medicine Hat, Alberta, MPA analysis of Sasketchewan wells (confirmed) 9) Morteza Abbaszadegan, Ariz. State Univ, Aerobic spores and MPA comparison in Cedar Rapids and Sioux City, IA PWS GWUDI wells (confirmed) 10) Tom Harter, UC Davis, CAFOs as Source of Groundwater Pathogens and the Role of Indicator Organisms (confirmed) 11) Bill Johnson, Univ of Utah, New Filtration Theory for Predicting Retention of Cryptosporidium Oocysts and other >2 micron particles in Porous Media under Environmental Conditions (confirmed) 12) Georg Reicher, Technical University, Vienna Austria, Indicator transport in alpine karst terrain (confirmed) Pathogens 1) Jack Schijven, RIVM, The Netherlands, Virus protection zones for community wells in The Netherlands (confirmed) 2) Tom Harter, UC Davis, Subsurface Fate and Transport Modeling of Cryptosporidium parvum (confirmed) 3) TBD, Fate and transport of pathogens in a fractured aquifer in the Salento area, Italy (pending) 4) Scott Bradford, USDA, E. coli O157 transport in saturated porous media (confirmed) 5) Kent Novakowski, Queens University, Ontario, The presence of viruses in sedimentary and crystalline rock aquifers in Canada (confirmed) 6) Pulin Modial and Brent Sleep, University of Toronto, Laboratory studies of colloid and virus transport in fractured rock (pending) ABSTRACT for the Key Presentation: The Sonoma Water Evaluation Drinking Water Intervention Gastrointestinal Illness in John M. Colford Jr., MD, C. Wright, MPH, Benjamin J. Wade, PhD, MPH, James PhD Trial: A Randomized Trial to Reduce Older Adults PhD, MPH, Joan F. Hilton, ScD, Catherine F. Arnold, MPH, Sona Saha, MPH, Timothy Scott, PhD, and Joseph N.S. Eisenberg, Objectives. We estimated the relative rate of highly credible gastrointestinal illness (HCGI) per year associated with active versus sham household water filtration devices among older adults in a community receiving tap water meeting current US standards. Methods. We conducted a randomized, triple-blinded, crossover trial in 714 households (988 individuals), which used active and sham water filtration devices for 6 months each. We estimated the annual incidence rate ratio of HCGI episodes and the longitudinal prevalence ratio of HCGI days at population and individual levels with a generalized estimating equation (GEE) and generalized linear mixed models (GLMMs), respectively, adjusted for covariates associated with outcome. Results. The incidence rate ratios (active versus sham) were 0.88 (95% confidence interval [CI] = 0.77, 1.00) and 0.85 (95% CI = 0.76, 0.94) HCGI episodes per year estimated by GEE and GLMM models, respectively. The corresponding longitudinal prevalence ratios were 0.88 (95% CI = 0.74, 1.05) and 0.84 (95% CI = 0.78, 0.90) HCGI days per person per year. Conclusions. We observed reductions in population- and individual-level measures of HCGI associated with use of the active filtration device. These findings suggest the need for further research on the impact of drinking water on the health of sensitive subpopulations. (Am J Public Health. 2009;99:XXX–XXX. doi:10.2105/AJPH.2008.153619) The agenda from LAST YEAR’s Symposium: EPA Symposium on Groundwater-Borne Infectious Disease, Etiologic Agents and Indicators -------------------------------------------------------------------------------December 2, 3, and 4, 2008 At The Carnegie Institute Of Washington 1530 P St. NW Washington DC -------------------------------------------------------------------------------Public Scientific Forum, All Are Welcome, Seating and Wi-Fi Available for 400 http://es.epa.gov/ncer/events/#dec0208 info and informal registration: Berger.philip@epa.gov Tuesday, December 2nd | Day: Carnegie Institute | of Washington Auditorium| 1530 P St. NW | (Evening: Terrace | Ballroom, Doubletree | Hotel | 1515 Rhode Island Ave. | NW) | (two blocks south) | ------------------------+-------------------------------------------------Ground Water | Epidemiology | ------------------------+-------------------------------------------------8:30 – 8:35 a.m. |Welcome, Audrey Levine, US EPA Office of Research |and Development ------------------------+-------------------------------------------------8:35 - 8:40 |Introduction, Pam Barr, US EPA Office of Water ------------------------+-------------------------------------------------8:40 - 9:10 a.m. |High-Throughput High-Volume Virus Testing of |Drinking Water: Protocols and Issues, Susan K. |Spencer, Marshfield Clinic Research Foundation, |Marshfield, WI (30 minutes) ------------------------+-------------------------------------------------9:10 – 9:30 a.m. |Discussion on “new” virus methods (e.g. glass |wool, NanoCeram filter, hollow-fiber |ultrafiltration…) ------------------------+-------------------------------------------------9:30 - 10:30 a.m. |Community-Wide Intervention with UV Disinfection |for Estimating Risk of Viral Illness from |Groundwater Consumption, Mark A. Borchardt, |Marshfield Clinic Research Foundation, Marshfield, |WI (60 minutes) ------------------------+-------------------------------------------------10:30 – 11:00 a.m. |Discussion on epidemiology studies (e.g. the |influence of “blinding” in intervention studies, |cost and severity of illness, population immunity |etc…) ------------------------+-------------------------------------------------11:00 a.m. - 11:45 a.m. |Risk Assessment of Acute Illness from Virus |Intrusions into Distribution Systems |Frank Loge and Elisabetta Lambertini, University |of California - Davis, Davis, CA (45 minutes) ------------------------+-------------------------------------------------11:45 – 12:00 p.m. |Discussion on recontamination of distribution |systems (e.g. implications for the forthcoming |TCR/Distribution System Rule) ------------------------+-------------------------------------------------12:00 - 1:00 p.m. |LUNCH (on your own) ------------------------+-------------------------------------------------1:00 – 1:15 p.m. |Discussion of the WAHTER Study results (e.g. |societal implications) ------------------------+-------------------------------------------------1:15 – 2:00 |The Epidemiology and Microbial Risk Assessment |(EMIRA) Study, 1998-1999, France, Dr. Pierre Le |Cann, France School of Public Health, Rennes, |France (45 minutes) ------------------------+-------------------------------------------------2:00 - 2:15 p.m. |Discussion on EMIRA (e.g. French public health |policy as the result of the EMIRA study) ------------------------+-------------------------------------------------2:15 – 3:00 p.m. |Seven-year Longitudinal Study at Walkerton |Ontario; The Walkerton Health Study, William |Clark, University of Western Ontario (45 minutes) ------------------------+-------------------------------------------------3:00 – 3:30 p.m. |Discussion on Walkerton (e.g. outbreak cost of |illness for acute phase versus chronic sequellae |disease, serendipitous findings?) ------------------------+-------------------------------------------------3:30 – 4:00 p.m. |A Population-based Study of Health Outcomes in |American Indian Communities Using Ground Water, |Yvonne Yuen, Public Health Fellow at USEPA (30 |minutes) ------------------------+-------------------------------------------------4:00 – 4:30 p.m. |Characterization and Modeling of Pathogen Risks in |Groundwater of First Nations Communities, Asit |Mazumder, University of Victoria, British Columbia |(30 minutes) ------------------------+-------------------------------------------------4:30 – 5:00 p.m. |Discussion on First Nation, AmerIndian, Ontario, |Wisconsin and French Alpine Groundwater Infectious |Disease Epidemiology: (e.g. Evaluation of current |results, extrapolation to other locales, future |prospects….) ------------------------+-------------------------------------------------5:00 – 7:00 p.m. |Dinner (on your own) ------------------------+-------------------------------------------------7:00 – 10:00 p.m. |Venue change to: |Terrace Ballroom, Doubletree Hotel, 1515 Rhode |Island Ave., N.W. (two blocks south) | |Discussion forum followed by presentation on: | |Does arsenic mitigation in Bangladesh raise |exposure to microbial and viral pathogens? |Alex van Geen, Columbia University and Brian |Mailloux, Barnard College Wednesday, December 3rd Day: Carnegie Institute of Washington Auditorium 1530 P St. NW (Evening: State Room, Doubletree Hotel 1515 Rhode Island Ave. NW) (two blocks south) Infectious Disease | Transmission and | Occurrence Models | ------------------------+-------------------------------------------------8:30 – 9:00 a.m. |The Potential Implications of Person-to-Person |Transmission of Viral Infection to US EPA's |Groundwater Rule, Jeff Soller, Soller |Environmental (30 minutes) ------------------------+-------------------------------------------------9:00 – 9:15 a.m. |Discussion on population dynamic infectious |disease transmission models (e.g. dynamic model |results compared with microbial risk assessment |results…) ------------------------+-------------------------------------------------9:15 – 9:45 a.m. |Enteric Virus and Fecal Indicator Occurrence in |Ground Water Sources of Public Drinking Water, |Mike Messner, US EPA (30 minutes) ------------------------+-------------------------------------------------9:45- 10:00 |Discussion on statistical models (e.g. How to turn |microbial ocurrence data into information) ------------------------+-------------------------------------------------10:00 – 10:30 a.m. |Microscopical Indicators Used for Warning of |Contamination in Drinking Water (two case studies |of outbreaks), Andrea Torok, National Institute |for Environmental Health, Budapest, Hungary (30 |minutes) ------------------------+-------------------------------------------------10:30 – 11:00 a.m. |Noroviruses in Groundwater: Outbreak |Investigations and Risk Characterization, Kellogg |Schwab, The Johns Hopkins University Bloomberg |School of Public Health (30 minutes) ------------------------+-------------------------------------------------11:00 – 11:15 a.m. |Discussion on Norovirus (e.g. secondary |transmission after drinking water exposure) ------------------------+-------------------------------------------------| ------------------------+-------------------------------------------------Pathogen Occurrence and | Transport | ------------------------+-------------------------------------------------11:15 - 11:45 a.m. |Cryptosporidium Infection and Onsite Wastewater |Disposal Systems in the Arid Southwest, Kristine |Tollestrup, University of New Mexico (30 minutes) ------------------------+-------------------------------------------------11:45 – 12:45 p.m. |LUNCH (on your own) ------------------------+-------------------------------------------------12:45 – 1:00 p.m. |Discussion on Bangladesh (e.g. untreated latrine |sewage blocks microbial attachment and mobilizes |arsenic?) ------------------------+-------------------------------------------------1:00 – 1:30 p.m. |Challenges to Predicting Microbial Transport |Distances in Porous Media Under the Simplest |Environmental Conditions: Crawling Before We Walk, |William P. Johnson, University of Utah (30 |minutes) ------------------------+-------------------------------------------------1:30 – 2:00 p.m. |Determination of Protection Zones for Dutch |Groundwater Wells Against Virus Contamination – |Uncertainty and Sensitivity Analysis, Jack |Schijven, RIVM The Netherlands (30 minutes) ------------------------+-------------------------------------------------2:00 – 2:30 p.m. |Transport and Retention of Selected Bacterial |Pathogens in Model Groundwater Environments, |Nathalie Tufenkji, McGill University, Montreal, |Canada (30 minutes) ------------------------+-------------------------------------------------2:30 – 3:00 p.m. |Microbial groundwater quality and its health |implications for border-strip and spray irrigated |dairy farm catchments in South Island, New |Zealand, Murray Close, Christchurch Science |Center, New Zealand (30 minutes) ------------------------+-------------------------------------------------3:00 – 3:30 p.m. |Discussion on coliphage and E. coli transport in |sand aquifers compared with gravel aquifers (e.g. |enterovirus and E. coli O157:H7 hazards…) ------------------------+-------------------------------------------------3:30 – 4:00 p.m. |Arcobacter spp., a Poorly Known Group of Bacteria |Already Associated with Two Well-Water Outbreaks |in the USA, Maria Jose Figueras, Univ. Rov. Virg., |Reus, Spain (30 minutes) ------------------------+-------------------------------------------------4:00 – 4:30 p.m. |Groundwater Microbiological Quality in Canadian |Drinking Water Municipal Wells, Annie Locas, INRS |Quebec (30 minutes) ------------------------+-------------------------------------------------4:30 – 5:00 p.m. | Discussion on pathogen occurrence (e.g. Is E. |coli a good pathogen indicator for ground water?) ------------------------+-------------------------------------------------5:00 – 7:00 p.m. |Dinner (on your own) ------------------------+-------------------------------------------------7:00 – 10:00 p.m. |Venue change to: |Terrace Ballroom, Doubletree Hotel, 1515 Rhode |Island Ave., N.W. (two blocks south) | |US Geological Survey Pathogens in Ground Water |Forum: | |Pathogen transport in karst ground water: An |overview of research advances, Barbara Mahler, |USGS, Austin, Texas (20 minutes) | |Groundwater Quality Impacts in Two Large Karstic |Spring Basins using Microbiological Indicators, |Dale Griffiths, USGS, Talahassee, Florida (20 |minutes) | |Subsurface Attenuation of Microorganisms Beneath |Septic Tank Drainfields in the Woodville Karst |Plain, Florida, Brian Katz, USGS, Talahassee, |Florida (20 minutes) | |Rapid molecular methods for detection of bacterial |contamination in karst, Bane Schill, USGS, |Kearneystown, West Virginia (20 minutes) | |Discussion ------------------------+-------------------------------------------------| | Thursday, December 4th | Carnegie Institute of | Washington Auditorium | 1530 P St. NW | ------------------------+-------------------------------------------------Pathogen Occurrence and | Transport | ------------------------+-------------------------------------------------8:30 – 9:00 a.m. |Viruses in US Ground Water: Hydrogeological and |Methodological Data Gaps, Dr. Shay Fout, USEPA (30 |minutes) ------------------------+-------------------------------------------------9:00 – 9:15 a.m. |Discussion on virus occurrence (e.g. Is |Enterovirus occurrence more likely in karst and |fractured bedrock aquifers?) ------------------------+-------------------------------------------------9:15 – 9:45 a.m. |Determination of Enteric Pathogen Survival in |Aquifers, Dr. Simon Toze, CSIRO, Australia (30 |minutes) ------------------------+-------------------------------------------------9:45 - 10:00 a.m. |Discussion on the use of native groundwater and |predation effects on enteric virus survival ------------------------+-------------------------------------------------10:00 – 10:30 a.m. |Gastrointestinal Pathogens in Patients with AGI |and Controls from Maryland, Connecticut and |Minnesota, Dr. Jon Mark Hirshon, University of |Maryland (30 minutes) ------------------------+-------------------------------------------------10:30 a.m. - 10:45 a.m. |Discussion on Emergency Room data (e.g. how to |assess sources of exposure?) ------------------------+-------------------------------------------------10:45 – 11:15 a.m. |Virus Survival in Ground Water, J. Scott Meschke, |University of Washington (30 minutes) ------------------------+-------------------------------------------------11:15 – 12:00 p.m. |Discussion on inactivation and ground water travel |times (e.g. is a one year protection zone |adequate?) End of Symposium From: "Wunderman, Richard" <WUNDERMA@si.edu> To: Philip Berger/DC/USEPA/US@EPA Date: 10/02/2009 05:27 PM Subject: RE: GSW Hello Philip, I just had a snack with the other Berger (Paul) and your name came up. There's an opening for a speaker on 27 Jan 2010 at GSW. We'd love to hear about this or other water-related topics. Yours, Rick Rick Wunderman (Global Volcanism Pgm., Smithsonian Inst.) -----Original Message----From: Berger.Philip@epamail.epa.gov [mailto:Berger.Philip@epamail.epa.gov] Sent: Friday, February 20, 2009 3:36 PM To: Wunderman, Richard Subject: GSW (See attached file: Viruses in Ground Water.ppt)