TOURO COLLEGE COURSE SYLLABUS

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TOURO COLLEGE COURSE SYLLABUS

LANDER COLLEGE

DEPARTMENT:

COURSE TITLE:

COURSE NUMBER:

PREREQUISITES:

CREDIT HOURS:

DEVELOPER:

LAST UPDATE:

COURSE DESCRIPTION:

Biology

Endocrinology

BIO 304

BIO 101, 102

4

Anthony J. Tolvo, Ph.D.

March 6, 2004

This course is designed to study the interactive physiology of mammals, with emphasis on the human organism, as regulated by the endocrine system. The course will cover the following areas: 1) cellular endocrinology, including hormone-receptor interactions, second messenger systems, and hormonal synthesis and secretion; 2) systemic endocrinology, including regulation of body metabolism and homeostasis, and reproductive endocrinology; 3) new trends in molecular endocrinology; 4) disease states due to endocrine malfunction.

COURSE/DEPARTMENTAL OBJECTIVES:

The student will:

Observe the intimate relationship between the controlled secretion of hormones and the response of target tissues in order to maintain cellular, tissue, organ, organ system and whole body homeostasis.

Analyze the current biochemical and molecular biological framework of research in endocrinology.

Develop a process of critical thinking, an ability to synthesize and correlate ideas from relevant scientific literature and to communicate the concepts effectively in both oral and written formats.

Will gain expertise in information literacy through extensive use of online library resources such as scientific databases in order to construct effective scientific queries on relevant topics in endocrinology.

Will develop an appreciation of the social and ethical implications and responsibilities of scientists involved in endocrine research.

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COURSE/INSTITUTIONAL OBJECTIVES:

This course is designed to provide students with a strong conceptual background in the biological and biochemical aspects of endocrine regulation. It provides a valuable area of scientific inquiry for those interested in pursuing graduate work in biology and medicine. Commensurate with this objective, the course is designed to fulfill the following institutional goals:

Foster and appreciation of scholarship and enhance research skills in the field of endocrinology.

Further pre-professional career interests of students interested in biology and associated clinical fields.

Enhance a global perspective with regard to modern biological experimentation and research.

COURSE CONTENT:

Cellular Endocrinology:

Autocrine, paracrine and endocrine regulation

Signal transduction and signal transduction pathways

Membrane receptor systems and cytoplasmic receptor systems

Synthesis and secretion of hormones

Post-transcriptional and post-translational processing of hormones

The Pituitary Gland:

Interrelationships between the central nervous system and the endocrine system

Embryological origins of the pituitary gland

Anatomical and physiological aspects of the anterior and posterior pituitary

Concepts of positive and negative feedback in hormone regulation

Neuroendocrine regulatory pathways

Peripheral Endocrine Glands/Tissues:

Thyroid gland

Adrenal hormones

Gonadal hormones

Secretions of the pancreas

The kidney as an endocrine organ

The heart as an endocrine organ

Regulation of calcium homeostasis

Interrelationships between peripheral endocrine tissues: the rennin-angiotensin system

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Endocrine Disease:

The basis of endocrine disease states

Gigantism and dwarfism

Thyroid disease states

Diabetes

Adrenal disease states

Post-menopausal and senile osteoporosis

HARDWARE/SOFTWARE/MATERIALS REQUIREMENTS:

Hardware/software:

Not applicable

Instructor materials:

Instructor desk copies of text(s) and appropriate ancillaries

Office PC for course-related word processing, spreadsheet, presentation tasks

Overhead projector

PC projection equipment

TV/VHS equipment

COURSE REQUIREMENTS:

Two sectional lecture exams

Semi-cumulative final lecture exam

Weekly lecture quizzes

Three sectional laboratory exams

Completion of laboratory “portfolio”

Attendance and participation

GRADING GUIDELINES:

Two sectional lecture exams……………………………………………..30%

Semi-cumulative final exam……………………………………………...20%

Term paper…………………………………………………………….….10%

Special Assignment (analysis of original research paper(s)……………...10%

Laboratory………………………………………………………………...30% o

Three laboratory exams……………………..75% o

Portfolio……………………………………..25%

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METHODOLOGY:

Lectures and laboratories should be enhanced using the following teaching tools:

Texts and appropriate primary and secondary sources from the scientific literature

Visual models and charts

Overhead transparencies and Powerpoint presentation materials

Relevant internet sites and searches

VHS videos on endocrinology and related topics

COURSE TEXTS:

Title: Basic and clinical endocrinology

Author:

Pub. Date:

Publisher:

Greenspan, F., Gardner, D. (ed.)

2003

ISBN #:

Appleton and Lange (Prentice-Hall)

0071402977

BIBLIOGRAPHY:

Title:

Author:

Pub. Date:

Publisher:

ISBN #:

Title:

Author:

Pub. Date:

Publisher:

ISBN #:

Title:

Author:

Pub. Date:

Publisher:

ISBN #:

William’s textbook of endocrinology

Williams, R.H., et al., (eds.)

2002

W.B. Saunders

0721691846

Endocrinology at a glance

Greenstein, B.J.

1994

Blackwell Science, Inc.

0632038357

Principles and practice of Endocrinology and metabolism

Becker, K.L. (ed.)

2002

Lippincott, Williams and Wilkins

0781742455

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