Anatomy and Physiology I Student Outline – The Integumentary System Integumentary System 1. Introduction (Open your text to the image of a cross section of skin) A. Integumentary System i. Organ of the Integument a. Tissues • Connective Tissues * • Tissue / Location Relationships Epithelial Tissues * Tissue Type / Relationships • Smooth Muscle • Nervous Tissue * • B. 2. Receptor Type / Function Relationships Blood Dermatology Functions of the Integument A. Thermoregulation (Review in text) i. Superficial Vasculature ii. Deep Vasculature Page 1 Anatomy and Physiology I Student Outline – The Integumentary System B. C. Protection from … i. Abrasion ii. UV Radiation iii. Invasion from pathogens iv. Desiccation Receives stimuli i. D. Synthesis of vitamin D E. Immunity i. 3. Receptor Types / Function Relationships Tissue and Related Functions Epidermis (Layer #1) (See diagrams in Text!) A. General Characteristics i. Keratinized Stratified Squamous Epithelium ii. Avascular iii. Basement Membrane iv. Epidermal Ridges (and Dermal Papilla) a. Two Functions Page 2 Anatomy and Physiology I Student Outline – The Integumentary System B. Cell Types i. Keratinocyte • ii. Melanocyte • iii. Keratinization Melanosomes Skin Color a. Melanin • Melanocytes • Function UV Rad iati on UV Rad iati on UV Rad iati on UV Rad iati on Page 3 Anatomy and Physiology I Student Outline – The Integumentary System C. Five Layers of the Epidermis i. Stratum Basale (Stratum germinativum) Stratum Spinosum • Desmosomes Stratum Granulosum Stratum Lucidum ii. D. 3. Stratum Corneum Epidermal Growth Factor (EFG) • Growth Factor • Hormone • Irregular Dense Connective Tissue Dermis A. Regions i. ii. Papillary Region • Dermal Papillae • Corpuscles of Touch • Superficial Vasculature Functions Reticular Region • Corpuscles of Pressure Page 4 Anatomy and Physiology I Student Outline – The Integumentary System B. 4. General Characteristics of the Dermis i. Fibers ii. Vascular iii. Muscle iv. Nerve Fibers v. Hair Follicles vi. Sweat Glands vii. Sebaceous Glands Subcutaneous Layer of the Integument A. B. Tissues i. Adipose Connective Tissue ii. Loose Areolar Connective Tissue Functions i. Thermoregulation ii. Vascular Protection iii. Adhesion iv. Page 5 Anatomy and Physiology I Student Outline – The Integumentary System 5. Accessory Structures A. Hair i. Hair follicle ii. Shaft iii. Arrector Pili Muscles iv. Sebaceous Glands v. Functions Nails B. i. Nail Bed ii. Lunula iii. Functions Skin Glands i. ii. Sebaceous Glands (Oil glands) • Holocrine Types • Sebum Merocrine Sweat Glands • iii. Tubular Apocrine Sweat Gland iii. Other Integumentary Glands a. Ceruminous Glands b. Mammary Glands Homeostasis of Temperature Body – review in text Page 6 Anatomy and Physiology I Student Outline – The Integumentary System C. Aging and Hair i. ii. 6. Hair Color a. Gray Hair b. White Hair Balding a. Genetic Predisposition b. Testosterone Deep Wound Healing (ESSAY using outline below, text, and lecture; describe Deep Wound Healing in your own words). A. Stabilization of Wound i. An initial break damages dermal blood vessels and inserts microorganisms ii. Reflexive vasoconstriction reduces blood flow iii. Platelets come in contact with collagen fibers and induce clotting iv. B. Clot forms are further reduces blood lose and isolates bacterial Inflammatory response i. Mast cells and Basophile secrete histamine ii. Histamine induces vasodilatoin of undamaged blood vessels Page 7 Anatomy and Physiology I Student Outline – The Integumentary System iii. Vasodilated vessels become porous allowing nutrients, oxygen and other resources to enter damaged area. iv. Pyrogen secreted elevates local temperature. v. Margination, Diapedesis, positive chemotaxis, and phagocytosis by neutrophils followed by macrophages. C. Injury Resolution i. Stratus basalis begins to grow. Blood vessels begin to repair ii. Fibroblasts migrate into damaged area and secrete collagen iii. Epidermis mends iv. Scab forms v. Clot material removed vi. D. Final Stages i. Normal blood flow restored ii. Bacterial and damaged tissue removed iii. Irregularly placed collagen leaves scar iv. Scab falls off. Page 8