Lecture: Intro to Nutrition, Nutrients, and Malnutrition What is nutrition? Why study nutrition? Diet-related causes of death Obesity rates The Changing American Diet Changes between 1970-2005 Introduction to the Nutrients What is a nutrient? 6 classes of nutrients: Macronutrients vs. micronutrients Definition of an essential nutrient o How can you tell if a nutrient is “essential”? Definition of organic nutrient: o Examples of organic nutrients o Examples of inorganic nutrients What’s an “organic food”? Nutrition 12 The Energy-Yielding Nutrients What is meant by “energy”? Form of chemical energy used in the body: The calorie: a unit of heat energy Calories provided by dietary substances: Carbohydrate Protein Lipids Alcohol Problem: Calculate the energy content of 1 serving of See’s milk chocolates: Total fat: 12 g Total carbohydrate: 27 g Protein: 3 g How many Calories in a milk chocolate? About what percent of its calories comes from fat? Recommendation for % of Calories from Energy-Yielding Nutrients Carbohydrate Protein Lipids Nutrient Density Definition of nutrient density Examples of nutrient-dense food choices General Functions of Nutrients 1. 2. 3. Body composition: water, protein, fat, minerals Examples of non-nutrients Phytochemicals Probiotics Functional foods defined: Introduction to Malnutrition Undernutrition vs. overnutrition Causes of nutrient deficiencies Primary Secondary Assessment of nutrition status A: B: C: D: Anthropometric data: Laboratory tests (Biochemical data): Physical examination (Clinical data): Dietary assessment: Examples: 24-hr recall Food frequency Food record (diet analysis) Stages in the Development of a Nutrient Deficiency: see figure in textbook… Introduction to Nutrition Research Finding reliable nutrition information… Which resource provides the most accurate information? Reputable Nutrition Credentials Examples include: Degree mills – do they provide expertise? Scientific Method in Nutrition Research Define the “scientific method.” Steps of the scientific method: 1. 2. 3. 4. Continuum of Reliability of Information Nutrition Studies I. Epidemiological studies Examples of Epidemiological Studies Cross-sectional study: Retrospective (case-control study): Prospective (cohort study): Evaluating relationships between variables Positive correlation Negative correlation No correlation More correlation terminology Epidemiological Studies: how results are expressed Summary: Elements of Epidemiological Studies o Find relationships o Observational o No “cause and effect” shown Question: Which type of study is more accurate… prospective or retrospective? Example of ongoing observational study NHANES – National Health and Nutrition Examination Surveys Experimental studies Prospective Intervention Random assignment Treatment vs. placebo Determine “cause and effect” relationships Elements of high-quality experimental studies Randomization Single blinded vs. double blinded Placebo controlled Peer review Replication The Placebo Effect Interpreting the results… Statistical significance Was treatment success due to the treatment, or luck (“chance”)? Clinical relevance Animal and Cell Culture Studies Animal studies Cell or tissue culture Making Sound Decisions about Nutrition Studies How do you know if nutritional claims are sound? Publication of Research Studies • Nutrition, medical, dietetics journals Peer Review See Table 1-3 (p. 13) and Figure 1-4 (p. 14)