Muscular System 1 Name: ________________________________________________________________________Lab________ Standard 5: Muscular System Indiana Content Standards AP 2.2 Compare and contrast the structure, function and location of cells that make up various types of muscle tissue… AP 5.1 Name the components of a skeletal muscle fiber and describe their functions. Describe how the thin and thick filaments are organized in the sarcomere. AP 5.2 Explain the molecular processes and biochemical mechanisms that provide energy for muscle contraction and relaxation. AP 5.3 Describe a motor unit and its importance in controlling the force and velocity of muscle contraction. Describe the neuromuscular junction and the neurotransmitter released at the neuromuscular junction. AP 5.4 Distinguish between isotonic and isometric contractions of skeletal muscle; cite examples of each and discuss how the forces generated in muscle contraction are amplified by the use of levers. AP 5.5 Identify the major muscles on a diagram of the body’s musculature, through dissection or both. Describe the movements associated with each muscle. AP 5.6 Explain what is meant by muscular hypertrophy and atrophy and discuss causes of these processes. Objectives Know the functions of the muscular system 2.2 Compare and contrast skeletal, cardiac and smooth muscle. 5.1 Name the components of the skeletal muscle fiber and describe their functions 5.2 Explain the sliding filament theory 5.3 Explain what occurs at the neuromuscular junction 5.3 Explain the difference between slow twitch and fact twitch muscle fibers 5.4 Give examples of isotonic and isometric muscle contractions. 5.4 Explain the effect the use of a lever has on muscle contractions. 5.5 Label diagram with the major muscles and functions of the muscular system 5.5 Describe the point of insertion and the point of origin 5.6 Give examples of the causes of muscular hypertrophy and atrophy and what is happening to the muscle in each Lecture Notes: Important Notes for the Test: The Muscular System Functions of the Muscular System 1. _________________________________________ 2. _________________________________________ ___________________________________________ ___________________________________________ 3. _________________________________________ ___________________________________________ ___________________________________________ ___________________________________________ There are ___________ muscles in our body! Know the functions of the muscular system. Muscular System 2 Three Types of Muscle 1. ___________________________________________ Label the three types of muscle: 2. ___________________________________________ 3. ___________________________________________ Smooth Muscle _____________________________________________ _____________________________________________ _____________________________________________ Examples of what smooth muscle does in our bodies: _____________________________________________ _____________________________________________ _____________________________________________ _____________________________________________ Cardiac Muscle _____________________________________________ _____________________________________________ _____________________________________________ _____________________________________________ Explain intercalated discs: _______________________ _____________________________________________ _____________________________________________ _____________________________________________ Skeletal Muscle _____________________________________________ _____________________________________________ Skeletal muscles attach to joints at points of: _____________________________________________ _____________________________________________ Made up of _______________ & __________________ muscle fibers. Know which are voluntary and involuntary. Know which are striated and which is not. Muscular System 3 Points of Origin and Insertion Label the point of origin and the point of insertion: Point of Origin: ________________________________ Point of Insertion: ______________________________ Fast Twitch Muscle Fibers _____________________________________________ _____________________________________________ _____________________________________________ _____________________________________________ Slow Twitch Muscle Fibers Distinguish between the characteristics of slow twitch _____________________________________________ and fast twitch muscle fibers. _____________________________________________ _____________________________________________ _____________________________________________ _____________________________________________ Structure of a Skeletal Muscle Fiber Muscle Fiber A muscle fiber is the muscle ___________. Myofibrils Located in the _______________________________. They are long strands of _______________________. Contain ________________ and ________________ filaments. Sarcomere A section of a myofibril that contains the actin and myosin needed to make a muscle _____________. Name the components of the skeletal muscle fiber. Actin Actin filaments are __________ protein fibers. They are Know the characteristics of the myofibril, sarcomere, attached to the ends of the sarcomere, called the actin and myosin. ________________. Pulling actin filaments causes the sarcomere to ___________________. Muscular System 4 Myosin Myosin filaments are ______________ protein fibers. They are attached to the center of a sarcomere which is called the _______________. Myosin fibers are responsible for the _________________ action that causes the sarcomere to __________________. Sarcomere Diagram Sarcomere Diagram Instructions: Sketch a relaxed and contracted You will have to recognize the difference between a sarcomere. Label the actin, myosin, z line and m line relaxed and contracted sarcomere diagram and label in each. each part. Sliding Filament Theory Complete the Sliding Filament Theory Exercise on the next page. Put steps 1 - 5 of the sliding filament theory in the correct order. Muscular System 5 Sliding Filament Theory Exercise The sliding filament theory explains muscle contraction based on how muscle fibers (actin and myosin) slide against each other to generate tension in the overall muscle. Step 1: A muscle contraction starts in the brain, where signals are sent along the motor neuron (a). Color the motor neuron yellow . Within the motor neuron are vesicles that contain the neurotransmitter, acetylcholine. Color vesicles gray and the triangles that represent the acetylcholine orange . Acetylcholine reaches the receptors (b) on the muscle sarcolemma which causes an impulse. Step 2: The impulse travels down the membrane and into the transverse tubules (c) where it causes calcium to be released from the sarcoplasmic reticulum. Color the t-tubule green and the circles that represent calcium dark blue . The sarcoplasmic reticulum is only partially pictured, shade this structure pink. Step 3: Calcium binds to a structure on the actin that causes it to change shape. Color the actin myofilament (e) red. Step 4: The change in shape allows myosin heads to form cross-bridges between the actin and the myosin. Color the myosin (g) blue. Color the cross bridges (f) purple. Step 5: Energy from ATP is used to create a "power stroke" between the two filaments. Color the ATP bright orange The actin filament then slides inward and shortens, or contracts, the whole muscle. . Muscular System 6 Increase or Loss of Muscle Tissue: Hypertrophy Muscles grow when they are exposed to ____________ __________ causing microscopic damage. When this happens the body releases __________________that activate the immune system telling the body to repair the damage. The repetitive process of damage and repair eventually makes muscles _____________ & _______________. This increase in mass due to exposure to increased resistance is called __________________. The body’s ability to repair muscle is also affected by __________________________________________ __________________________________________ __________________________________________ Atrophy When muscles are not exposed to resistance they _________. This process is known as ______________. Isotonic Contractions There _______ movement with isotonic exercise. Isotonic contractions __________muscle tissue. Isometric Contractions Isometric contractions are ______________ exercises. There ___________movement with isometric exercise. Isometric contractions ____________muscle tissue. Muscular System 7 Major Muscles and Functions Reference Sheet Muscular System 8 Major Muscles and Functions Work Sheet