Online Appendix for the following October 20, 2009, JACC article
TITLE: Is a Pre-Operative Brain Natriuretic Peptide or N-Terminal Pro–B-Type
Natriuretic Peptide Measurement an Independent Predictor of Adverse Cardiovascular
Outcomes Within 30 Days of Noncardiac Surgery? A Systematic Review and MetaAnalysis of Observational Studies
AUTHORS: Ganesan Karthikeyan, MD, DM, Ross A. Moncur, BSC, Oren Levine,
BSC, Diane Heels-Ansdell, MSC, Matthew T. V. Chan, MD, MSC, Pablo AlonsoCoello, MD, MSC, Salim Yusuf, MBBS, DPHIL, Daniel Sessler, MD, Juan Carlos
Villar, MD, PHD, Otavio Berwanger, MD, PHD, Matthew McQueen, MB, CHB, PHD,
Anna Mathew, MD, Stephen Hill, PHD, Simon Gibson, MD, Colin Berry, MD, HueiMing Yeh, MD, P. J. Devereaux, MD, PHD
APPENDIX
Search strategy
Searches were performed using the OvidSP search engine (Ovid Technologies, Inc.,
2008). The databases selected were as follows:
1. Ovid version of MEDLINE (Ovid MEDLINE In-Process and other NonIndexed Citations and Ovid MEDLINE, 1950 to April week 3, 2008)
2. EMBASE (1980 to 2008, week 15)
3. Cochrane Central Register of Controlled Trials (first quarter 2008)
4. Cochrane Database of Systematic Reviews (first quarter 2008)
5. ACP Journal Club (1991 to March/April 2008)
Search terms
1
2
3
(BNP or NT Pro-BNP or N-Terminal pro-Brain Natriuretic
Peptide or Brain Natriuretic Peptide).mp.
(Surgery or non-cardiac surgery or pre-operative or postoperative).mp.
1 and 2 (articles for title and abstract screening)*
Number of
references
12274
1284669
564
*Includes an additional article identified by screening reference lists and 2
dissertations that were identified by a separate search of ProQuest.