FOR THE
21ST
SCIENTIFIC PROGRAM
INTERNATIONAL CHARLES HEIDELBERGER SYMPOSIUM
ON CANCER RESEARCH
Wednesday, May 25, 2016
Introductory Session: Chairmen: Dr. Lyudmilla Gulyaeva, Novosibirsk State
University, Novosibirsk, Russia, and Dr. Sergei Kovalenko, Novosibirsk, Institute of
Biophysics and Molecular Biology, Novosibirsk, Russia.
8:30 – 8:40 A. M. Dr. Lyudmila Gulyaeva, Conference Chair: Introductory Remarks.
8:40 – 8:50 A. M. Dr. Sergei Kovalenko
8:50 – 9:10 A. M. Introduction of Important Officials of Hosting University
9:10 – 9:25 A. M. Dr. Eliezer Huberman -
Introduction to the First Charles Heidelberger Symposium on Cancer Research
9:25 – 9:45 A. M. Dr. Joseph R. Landolph, Jr.- Introduction to the Career of Dr. Charles
Heidelberger, the Charles and Patricia
Heidelberger Foundation for Cancer Research, and Continuing Heidelberger
Symposia on Cancer Research
9:45 A. M. – 10:15 A. M.
Coffee Break
Session I: Cancer Cause and Prevention; Chairman: Dr. Xiao Nong Zou, National
Cancer Center and Cancer Institute of CAMS, Beijing, The People’s Republic of
China, and Dr. David Zaridze, Blokhin Russian Cancer Research Centre, Moscow,
Russia
10:20 A. M. – 10:50 A. M.
Dr. David Zaridze, Blokhin Russian Cancer Research
Centre, Moscow, Russia: “Epidemiology and Prevention of
Cancer”
10:50 A. M. – 11:20 A. M.
Dr. Xiao Nong Zou, National Cancer Center, Cancer Institute of CAMS, Beijing, People’s Republic of China: “Increased Lung cancer Mortality Rate in the Chinese Population from l973-l975 to 2004-20045: An Adverse Health
Effect of Exposure to Smoking”.
Plenary Lecture I: Chairman: Dr. Curtis Harris, National Cancer Institute,
National Institutes of Health, Bethesda, Maryland, U. S. A.
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11:20 A. M. – 12:20 P. M. Dr. Sir Colin Berry, University of London, London,
England, United Kingdom: Plenary Lecture I: “Problems
in the Regulatory Evaluation of Potential Carcinogens.”
12:30 P. M. – 2:00 P. M.
Lunch
Session II: Molecular Carcinogenesis. Chairmen: Dr. Joseph R. Landolph, Jr.,
University of Southern California, Los Angeles, Calif.,
U. S. A., and Dr. Max Costa, New York University,
Tuxedo, New York, U. S. A.
2:00 P. M. – 2:30 P. M.
Dr. Max Costa, School of Medicine, New York University,
Tuxedo, New York: “Arsenic Induces the Highly Carcinogenic Polyadenylation of Canonical Histone mRNA by
Down-Regulating Stem-Loop Binding Protein”
2:30 P. M. – 3:00 P. M.
Dr. Aage Haugen, Dept. of Toxicology, National Institute
of Occupational Health, Oslo, Norway: “Inflammatory and
Epigenetic Regulation in Lung Cancer.”
3:00 P. M. – 3:30 P. M.
Dr. Joseph R. Landolph, Jr., USC/Norris Comprehensive
Cancer Center, University of Southern California, Los
Angeles, California, U. S. A. “Insoluble Carcinogenic
Nickel Compounds Induce Morphological and Neoplastic
Transformation and Global Disruption of Gene Expression
in C3H/10T1/2 Mouse Embryo Fibroblasts”.
3:30 P. M. – 4:00 P. M.
Coffee Break
4:00 P. M. – 4:30 P. M.
Dr. Herman Autrup, Aarhus Universitetet, Arhus,
Denmark: “Genotoxicity of Nanomaterials”
4:30 P. M. – 5:00 P. M.
Dr. Yoshimi Homma, School of Medicine, Fukushima University, Fukushima, Japan: “Enhanced Metabolic ROS
Production by a Loss of Protein Phosphorylation in Mitochondria”
5:00 P. M. – 6:00 P. M.
Networking Time and Free Time
6:00 P. M. – 8:00 P. M.
Dinner
Thursday, May 26, 2016
Session III: Cancer Biology. Chairmen: Dr. Lyudmila Gulyaeva, Institute of
Molecular Biology and Biophysics, Novosibirsk State University, Novosibirsk,
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Russia, and Dr. Wei Li, USC/Norris Comprehensive Cancer Center, Keck School of
Medicine, University of Southern California, Los Angeles, California, U. S. A.
8:30 A. M. – 9:00 A. M.
Dr. Ping Gao, University of Science and Technology of
China, Heifei University, Heifei, Peoples’ Republic of
China: “Regulation of Cancer Metabolic Reprogramming”
9:00 A. M. – 9:30 A. M.
Dr. Lyudmila Gulyaeva, Institute of Molecular Biology
and Biophysics and Novosibirsk State University, Novosibirsk, Russia: “Role of MicroRNA in Mechanisms of
Hormonal Carcinogenesis”
9:30 A. M. – 10:00 A. M.
Dr. Irina Demidova Moscow Oncological Hospital #62,
Moscow, Russia: “Genetic Disorder in Non-Small Cell
Lung Cancer”
10:00 A. M. – 10:30 A. M.
Coffee Break
10:30 A. M. – 11:00 A. M.
Dr. Mikhail Krasil’kikov, N. N. Blokhin Russian Cancer
Research Center, Moscow, Russia: “Cell Signaling and the
Development of the Resistant Phenotype of Tumor Cells”
11:00 A. M. – 11:30 A. M.
Dr. Wei Li, USC/Norris Comprehensive Cancer Center,
Keck School of Medicine, University of Southern California, Los Angeles, California, U. S. A. “The Extra-Cellular
Function and Mechanisms of Action by Heat Shock Protein-90 alpha (HSP90α)”
11:30 A. M. – 12:00 P. M.
Dr. Arne Klungland, Center for Molecular Biology and
Neuroscience, BIG CAS-OSLO Genome Research Corporation, and University Hospital, Rikshospitalet, Oslo, Norway: “Reversible Modifications in RNA”
12:00 P. M. – 12:30 P. M.
Dr. Miwako K. Homma, School of Medicine, Fukushima
Medical University, Fukushima, Japan: “Function of
protein kinase CK2 on cell cycle progression”
12:30 P. M. – 2:00 P. M.
Lunch
Plenary Lecture 2. Chairman: Dr. Aage Haugen, Dept. of Toxicology,
National Institute of Occupational Health, Oslo, Norway
2:00 P. M. – 3:00 P. M.
Dr. Curtis Harris, National Cancer Institute, National
Institutes of Health, Bethesda, Maryland, U. S. A.
Plenary Lecture 2: “Aging and Cancer”
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Session IV: Cancer Diagnostics. Chairmen: Dr. Sergei P. Kovalenko, Institute of
Molecular Biology and Biophysics, Novosibirsk, Russia, and Dr. Sergey Shevchenko, Surgical Pathology Unit, Novosibirsk State University, and Head and Neck
Surgery Department, Novosibirsk Clinical Hospital No. 1, Novosibirsk, Russia
3:00 P. M. – 3:30 P. M.
Dr. Maxim Filipenko, Institute of Chemical Biology and
Fundamental Medicine, Novosibirsk, Russia: “Digitizing
of Onco-markers in Clinical Diagnostics”
3:30 P. M. – 4:00 P. M
Coffee Break
4:00 P. M. – 4:30 P. M.
Dr. Sergei P. Kovalenko, Institute of Molecular Biology
and Biophysics, Novosibirsk, Russia: “NGS in Hereditary
Cancer Diagnostics”
4:30 P. M. – 5:00 P. M.
Dr. Sergey Shevechenko, Surgical Pathology Unit,
Novosibirsk State University, Head and Neck Surgery
Dept., Novosibirsk Clinical Hospital No. 1, Novosibirsk,
Russia: “Clinical and Molecular-Genetic Approaches to
Diagnostics and Treatment of Thyroid Cancer”
5:00 P. M. – 5:30 P. M.
To Be Determined
6:00 P.M. – 8:00 P. M.
Dinner
Friday, May 27, 2016
Session V.
Neuro-Oncology. Chairman: Dr. Clark Chin-Chung Chen, Division
of Neurosurgery, Dept. of Surgery, University of California at San
Diego, San Diego, U. S. A. and Dr. Mihkail F. Chernov, Dept. of
Neurosurgery, Tokyo Women’s Medical University, Tokyo , Japan
8:30 A. M. – 9:00 A. M.
Dr. Marina G. Sergeeva, A.N. Belozersky Institute of
Physico-Chemical Biology, Moscow State University,
Moscow, Russia: “Coexpression Network Analysis of
Glioma Transcriptome”
9:00 A. M. – 9:30 A. M.
Dr. Clark Chin-Chun Chen, Division of Neurosurgery,
Dept. of Surgery, Univ. of California at San Diego, San
Diego, California: “Micro-Vesicles as a Platform for
Glioma Diagnostic and Therapeutic Development”
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9:30 A. M. – 10:00 A. M.
Dr. Ian E. McCutcheon, Dept. of Neurosurgery, University
of Texas M. D. Anderson Cancer Center, and Dept of
Neurosurgery, Baylor College of Medicine, Houston,
Texas: “Rational Clinical Trials of Targeted Kinase
Therapy for Hemangioblastoma”
10:00 A. M. – 10:30 A. M. Dr. Mihkail F. Chernov, Dept. of Neurosurgery,
Tokyo Women’s Medical University, Tokyo, Japan:
“Radiosurgery for Management of Brain Tumors
10:30 A. M. – 11:00 A. M. Dr. Alexei L. Krivoshapkin, Neurosurgery Department,
Novosibirsk State Medical University, Novosibirsk, Russia,
and Neurosurgery Dept., European Medical Center, Moscow, Russia: “Computerized Technologies for Cerebral
Malignant Glioma Maximum Safe Resection and PostOperative Assessment”
11:00 A. M. – 11:30 A. M.
Coffee Break
Session VI. Breast Cancer. Chairmen: Dr. Gloria Calaf, University of Tarapaca,
Arica, Chile and Columbia University, New York, New York, U. S. A., and Dr.
Debra Tonetti, College of Pharmacy, University of Illinois at Chicago, Chicago,
Illinois, U. S. A.
11:30 A. M. -12:00 A. M.
Dr. Gloria Calaf, Instituto de Alta Investigacion,
Universidad de Tarapaca, Arica, Chile and Center for
Radiological Research, Columbia University, New York,
New York, U. S. A.: “5-Fluorouracil and Curcumin Inhibit
The Epithelial-Mesenchymal Transition in Breast Carcinogenesis”
12:00 A. M. – 12:30 P. M.
Dr. Debra Tonetti, College of Pharmacy, University of
Illinois at Chicago, Chicago, Illinois, U. S. A.:” Selective
Estrogen Mimics for the Treatment of Tamoxifen-Resistant
Breast Cancer Using PKCα as a Predictive Biomarker”
12:30 P. M. – 1:30 P. M.
Lunch
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Plenary Session III: Chairman: Dr. Eliezer Huberman, CEO, Nova Drug, LLC,
and School of Pharmacy, University of Illinois at Chicago, Chicago, Illinois, U. S. A.
1:30 P. M. – 2:30 P. M.
Dr. Israel Vlodavsky, Cancer and Vascular Biology
Research Center, Rapaport Faulty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel. Plenary Lecture III: “Heparanase and Cancer Metastasis”
Session VII. Viral Chemotherapy and Cancer Chemotherapy. Chairmen: Dr. Eliezer Huberman, NOVA Drug, LLC and University of Illinois at Chicago, Chicago,
Illinois, and Dr. Karl-Heinrich Link, Surgical Center and Asklepios Tumor Treatment Center, Asklepios Paulinen Klinik, Weisbaden, Germany
2:30 P. M. – 3:00 P. M.
Dr. Evgeny N. Imyanitov, Dept. of Medical Genetics and
N. N. Petrov Institute of Oncology, St. Petersburg Pediatric
Medical Academy, and Dept. of Oncology, I. I. Mechnikov
North-Western Medical University, Saint Petersburg,
Russia: “Hereditary Cancer Syndrome: From Molecular
Biology of Specific Therapy”
3:00 P. M. – 3:30 P. M.
Dr. Eliezer Huberman, NOVA Drug, LLC and School of
Pharmacy, University of Illinois at Chicago, Chicago,
Illinois, U. S. A.: “Potential Drugs to Control Hazardous
Viruses, Including Some Involved in Human Malignancies”
3:30 P. M. – 4:00 P. M.
Dr. Karl-Heinrich Link, Surgical Center and Asklepios
Tumor Treatment Center Rhein/Main (ATC), Asklepios
Paulinen Klinik (APK), Weisbaden, Germany: “Modern
Surgical Oncology in General and Visceral Surgery”
4:00 P. M. – 4:30 P. M.
Coffee Break
4:30 P. M. – 5:00 P. M.
Dr. Marko Kornmann, Department of General and Visceral
Surgery, University of Ulm, Ulm, Germany: “The Role of
Predictive Biomarkers in the Treatment of Advanced Colorectal Cancer”
5:00 P. M. – 5:30 P. M.
Dr. Nadezhda V. Cherdyntseva, Dept. of Molecular Oncology and Immunology, Tomsk Cancer Research Institute,
Tomsk, Russia: “The Tumor Microenvironment as a Promising Target to Anti-Tumor Therapy”
5:30 P. M. – 6:00 P. M.
Coffee Break
6:00 P. M. – 6:30 P. M.
Dr. Robert Ladner, School of Medicine and the Cancer
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Center, Queen’s University, Belfast, Ireland, United
Kingdom: “Title to be determined.”
6:30 P. M. – 6:45 P. M.
Dr. Joseph R. Landolph, Jr. Concluding Remarks Summarizing Key Scientific Points of the Talks of the 21st Heidelberger Symposium.
6:45 P. M. – 7:00 P. M.
Dr. Lyudmila Gulyaeva. Final Statements and Concluding
Remarks Closing the 21st International Charles
Heidelberger Symposium.
7:00 P. M. – 9:00 P. M.
Dinner
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