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Quiz name: genomes and gene regulation 2 (KK)
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SOC-92595
Question 1 (Multiple Choice):
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Question: What are chromosomes made of?
Answer 1: DNA and proteins
Answer 2: DNA, RNA and proteins
Answer 3: DNA and euchromatin
Answer 4: DNA, heterochromatin and histones
Answer 5: DNA
Question 2 (Multiple Choice):
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Question: Transcription in eukaryotes requires in addition to RNA polymerase....
Answer 1: ribosomes and tRNA
Answer 2: start and stop codons
Answer 3: aminoacyl synthetase
Answer 4: several transcription factors
Answer 5: the protein product of the promoter
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Question: A eukaryotic transcript unit is 8000 nucleotides long, uses 1200 nucleotides to make a protein consisting of 400 amino acids. This is explained
Answer 1: there are terminators exons near the beginning of mRNA
Answer 2: nucleotides break off and are lost during transcription
Answer 3: there is redundancy in the genetic code
Answer 4: many non coding stretches of nucleotides are present in the DNA
Answer 5: mayn nucleotides are needed to code for each amino acid
Question 4 (Multiple Choice):
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Question: DNA methylation is used by eukaryotes to...
Answer 1: inactivate genes
Answer 2: cause apoptosis
Answer 3: increase transcription
Answer 4: terminate transcription
Answer 5: facilitate binding of DNA to enzymes
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Question: Why is gene expression more likely to be altered post-transcriptionally in eukaryotes than in prokaryotes?
Answer 1: prokaryotic genes are expressed as mRNAs that are more stable in the cell
Answer 2: eukaryotic mRNA is capped and contains polyA tails
Answer 3: prokaryotes use ribosomes of different structure and size
Answer 4: eukaryotic exons may be spliced in alternative patterns
Answer 5: Eukaryotic polypeptides often require cleaving of signal sequences before localization
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07.03.12 10:44
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Quiz name: Genregulation und Evolution (KK)
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SOC-92675
Question 1 (Short Answer):
Question: Welche Mechanismen sind dabei treibende Kräfte?
Question 2 (Multiple Choice):
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Question: In einem Experiment wurde das menschliche Chromosoms 21 in die Maus eingebracht und das Genexpressionsmuster dieses Chromosoms in de
Answer 1: Die Maus-DNA und die menschliche DNA sind so homolog, das humane DNA in Mauszellen exprimiert werden kann.
Answer 2: Regulatorische Elemente der DNA sind primär für die Genexpression verantwortlich.
Answer 3: Epigenetische Effekte regulieren die Expression der Gene auf dem Chromosom 21.
Answer 4: Transkriptionsfaktoren der Maus sind verantwortlich für die Regulation der Expression der menschlichen Gene.
Answer 5: Elemente auf der Maus-DNA können mit denen auf der menschlichen DNA wechselwirken, um die Genexpression zu regulieren.
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Question: The functioning of a CRE is an example of
Answer 1: a eukaryotic equivalent of prokaryotic promoter functioning.
Answer 2: a post-transcriptional mechanism to regulate mRNA.
Answer 3: the stimulation of translation by initiation factors.
Answer 4: transcriptional control of gene expression.
Answer 5: post-translational control that activates certain proteins.
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Question: Within a cell, the amount of protein made using a given mRNA molecule depends partly on
Answer 1: the presence of certain transcription factors.
Answer 2: the degree of DNA methylation.
Answer 3: the rate at which the mRNA is degraded.
Answer 4: the number of introns present in the mRNA.
Answer 5: the types of ribosomes present in the cytoplasm.
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07.03.12 10:45
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Quiz name: Krebsentstehung (KK)
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SOC-94458
Question 1 (Multiple Choice):
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Question: Which of the following would be most likely to lead to cancer?
Answer 1: failure of a proto-oncogene to produce a protein and amplification of a tumor-suppressor gene
Answer 2: hyperactivity of both a proto-oncogene and a tumor-suppressor gene
Answer 3: hyperactivity of a proto-oncogene and activation of a tumor-suppressor gene
Answer 4: amplification of a proto-oncogene and inactivation of a tumor-suppressor gene
Answer 5: failure of both a proto-oncogene and a tumor-suppressor gene to produce proteins
Question 2 (Multiple Choice):
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Question: All your cells contain proto-oncogenes, which can change into cancer-causing genes. Why do cells possess such potential time bombs?
Answer 1: Proto-oncogenes are necessary for the normal control of cell growth and division.
Answer 2: Cells produce proto-oncogenes as a by-product of mitosis.
Answer 3: Proto-oncogenes are unavoidable environmental carcinogens.
Answer 4: Proto-oncogenes are genetic junk that has not yet been eliminated by natural selection.
Answer 5: Proto-oncogenes protect cells from infection by cancer-causing viruses.
Question 3 (Multiple Choice):
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Question: Tumor-suppressor genes
Answer 1: are frequently overexpressed in cancerous cells.
Answer 2: are cancer-causing genes introduced into cells by viruses.
Answer 3: often encode proteins that stimulate the cell cycle.
Answer 4: can encode proteins that promote DNA repair or cell-cell adhesion.
Answer 5: do all of the above.
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Question: For a chemotherapeutic drug to be useful for treating cancer cells, which of the following is most desirable?
Answer 1: It is safe enough to limit all apoptosis.
Answer 2: It interferes with rapidly dividing cells.
Answer 3: It interferes with cells entering G0.
Answer 4: It only attacks cells that are density dependent.
Answer 5: It does not alter metabolically active cells.
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Question: You have a series of cells, all of which were derived from tumors, and you first need to find out which ones are malignant. What could you do?
Answer 1: See which ones are not overproliferating.
Answer 2: Measure metastasis.
Answer 3: Find out which ones have a higher rate of apoptosis.
Answer 4: Time their cell cycles.
Answer 5: Karyotype samples to look for unusual size and number of chromosomes
Question 6 (Multiple Choice):
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Question: What is true of all cancers?
Answer 1: They have escaped normal cell cycle controls.
Answer 2: They are caused by chemical carcinogens.
Answer 3: They are inherited.
Answer 4:
Answer 5:
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Question: The cell cycle control systems of cancer cells differ from those of normal cells. Select the best explanation for this fact.
Answer 1: Genetic changes alter the function of the cancer cell’s protein products.
Answer 2: Cancer cells divide excessively and invade other tissues.
Answer 3: Cancer cells are immortal.
Answer 4:
Answer 5:
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Quiz Name and Sharing
Quiz name: Entwicklung Mehrzelliger Organismen (KK)
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SOC-109665
Question 1 (Short Answer):
Question: Please enter your last name, first name (ex. West, Michael):
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Question: The first stage of embryonic development is _____. This process produces _____.
Answer 1: ovulation ... a zygote
Answer 2: parturition ... a fetus
Answer 3: gastrulation ... a three-layered embryo
Answer 4: neurulation ... a neurula
Answer 5: cleavage ... a cluster of cells
Question 3 (Multiple Choice):
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Question: Cells move to new positions as an embryo establishes its three germ tissue layers during
Answer 1: gastrulation.
Answer 2: fertilization.
Answer 3: cleavage.
Answer 4: determination.
Answer 5: induction.
Question 4 (Multiple Choice):
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Question: From earliest to latest, the overall sequence of early development proceeds in which of the following sequences?
Answer 1: organogenesis → neurulation → cleavage
Answer 2: gastrulation → organogenesis → cleavage
Answer 3: cleavage → gastrulation → organogenesis
Answer 4: cleavage → organogenesis → gastrulation
Answer 5: gastrulation → blastulation → neurulation
Question 5 (Multiple Choice):
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Question: How is it possible for a single zygote to give rise to all the cell types in a multicellular organism?
Answer 1: Some cells contain maternal chromosomes and some contain paternal chromosomes.
Answer 2: The DNA in each cell changes so that the appropriate proteins are produced.
Answer 3: Paternal effect genes begin the process of differentiation by providing positional information.
Answer 4: They differentiate through the process of mitosis.
Answer 5: Different genes are expressed so that different proteins are produced.
Question 6 (Multiple Choice):
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Question: Which of the following genes map out the basic subdivisions along the anterior-posterior axis of the Drosophila embryo?
Answer 1: homeotic genes
Answer 2: egg-polarity genes
Answer 3: morphogens
Answer 4: inducers
Answer 5: segmentation genes
Question 7 (Multiple Choice):
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Question: The product of the bicoid gene in Drosophila provides essential information about
Answer 1: the anterior-posterior axis.
Answer 2: the left-right axis.
Answer 3: the dorsal-ventral axis.
Answer 4: lethal genes.
Answer 5: segmentation.
Question 8 (Multiple Choice):
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Question: Mutations in which of the following genes lead to transformations in the identity of entire body parts?
Answer 1: homeotic genes
Answer 2: egg-polarity genes
Answer 3: morphogens
Answer 4: inducers
Answer 5: segmentation genes
Question 9 (Multiple Choice):
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Question: Muscle cells differ from nerve cells mainly because they
Answer 1: have different chromosomes.
Answer 2: contain different genes.
Answer 3: have unique ribosomes.
Answer 4: use different genetic codes.
Answer 5: express different genes.
Question 10 (Multiple Choice):
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Question: Which of the following statements about the DNA in one of your brain cells is true?
Answer 1: The majority of genes are likely to be transcribed.
Answer 2: It is the same as the DNA in one of your heart cells.
Answer 3: Many genes are grouped into operon-like clusters.
Answer 4: Each gene lies immediately adjacent to an enhancer.
Answer 5: Most of the DNA codes for protein.
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Quiz Name and Sharing
Quiz name: Gentechnologie (KK)
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SOC-127926
Question 1 (Multiple Choice):
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Question: Which "ingredients" for PCR and for the dideoxy chain-termination method of DNA sequencing are the same?
Answer 1: template DNA, reverse transcriptase, DNA primers
Answer 2: free nucleotides, DNA polymerase, DNA primers
Answer 3: nucleic acid probes, DNA polymerase, DNA ligase
Answer 4: RNA, reverse transcriptase, free nucleotides
Answer 5: enucleated eggs, reverse transcriptase, free nucleotides
Question 2 (Multiple Choice):
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Question: A gene that contains introns can be made shorter (but remain functional) for genetic engineering purposes by using
Answer 1: reverse transcriptase to reconstruct the gene from its mRNA.
Answer 2: RNA polymerase to transcribe the gene.
Answer 3: DNA polymerase to reconstruct the gene from its polypeptide product.
Answer 4: DNA ligase to put together fragments of the DNA that code for a particular polypeptide.
Answer 5: a restriction enzyme to cut the gene into shorter pieces.
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Question: For a particular microarray assay (DNA chip), cDNA has been made from the mRNAs of a dozen patients' breast tumor biopsies. The researchers will be looking for
Answer 1: a group of cDNAs that act differently from those on the rest of the grid.
Answer 2: a particular gene that is amplified in all or most of the patient samples.
Answer 3: a pattern of fluorescence that indicates which cells are overproliferating.
Answer 4: a pattern shared among some or all of the samples that indicates gene expression differing from control samples.
Answer 5: a group of cDNAs that match those in non-breast cancer control samples from the same population.
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Question: Which of the following tools of recombinant DNA technology is incorrectly paired with its use?
Answer 1: DNA polymerase-polymerase chain reaction to amplify sections of DNA
Answer 2: DNA ligase-cutting DNA, creating sticky ends of restriction fragments
Answer 3: reverse transcriptase-production of cDNA from mRNA
Answer 4: electrophoresis-separation of DNA fragments
Answer 5: restriction enzyme-analysis of RFLPs
Question 5 (Multiple Choice):
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Question: Which of the following would not be true of cDNA produced using human brain tissue as the starting material?
Answer 1: It could be used as a probe to detect genes expressed in the brain.
Answer 2: It could be used to create a complete genomic library.
Answer 3: It was produced from mRNA using reverse transcriptase.
Answer 4: It could be amplified by the polymerase chain reaction.
Answer 5: It lacks the introns of the human genes.
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Question: A principal problem getting an eukarytotic gene expressed in bacteria, is that
Answer 1: bacteria translate only mRNAs that have multiple messages.
Answer 2: bacterial DNA is not found in a membrane-bounded nucleus and is therefore incompatible with mammalian DNA.
Answer 3: bacteria cannot remove eukaryotic introns.
Answer 4: bacterial RNA polymerase cannot make RNA complementary to mammalian DNA.
Answer 5: prokaryotes use a different genetic code from that of eukaryotes.
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