11.1 BASIC PATTERNS OF HUMAN INHERITANCE NAME__________________________HR___
APPLICATION NOTES
 REVIEW VOCAB
DEFINE:
gene __________________________________________________________________________________
carrier _________________________________________________________________________________
 RECESSIVE/ DOMINANT GENETIC DISORDERS
COMPARE/CONTRAST recessive and dominant genetic disorders. PROVIDE 2 examples for each type of disorder.
RECESSIVE GENETIC DISORDERS DOMINANT GENETIC DISORDERS
1- _______________________________ 1- ______________________________
2- _______________________________ 2- ______________________________
EXPLAIN why recessive disorders are more common than dominant disorders.
IDENTIFY the disorder for each description and IDENTIFY whether it is a recessive/dominant disorder
DISORDER DESCRIPTION
-caused by altered genes; results in lack of skin pigmentation
-characterized by body’s inability to tolerate galactose
-gene found on chromosome 15;characterized by lack of enzyme that breaks down fatty acids
-affects the nervous system; no treatment; breaks down part of brain; rare dom allele
D R
PREDICT:
-affects mucus-producing glands, digestive enzymes, sweat glands
-affects height and body size
1-Show a cross between two heterozygous individuals using a Punnett square.
-what is the probability that 2 carriers of cystic fibrosis will have a child with CF.
2-Can 2 normal height parents have a child with achondroplasia? _______________
-Can 2 individuals with achondroplasia have a child that is normal height? _______________
-COMPLETE Punnett squares to support your answer.

 PEDIGREES
SUMMARIZE pedigree symbols by naming them then drawing the symbol in the table.
INFO DESCRIPTION SYMBOL male female affected male affected female carrier=known heterozygous parents generation represented
 STEPS for INTERPRETING PEDIGREES
1-DETERMINE if the pedigree is showing AUTOSOMAL or X-LINKED disorder
-AUTOSOMAL: _____________________________________________________
-X-LINKED: ________________________________________________________
2-DETERMINE if the disorder is DOMINANT or RECESSIVE
-DOMINANT: ______________________________________________________
-RECESSIVE: _______________________________________________________
 ANALYZING PEDIGREES
EVALUATE the inheritance of achondroplasia shown in the pedigree
-parent with achondroplasia
-# of children with achondroplasia
-genotype of younger son
____________________
__________
__________
ANALYZE / RESPOND to each question using the pedigree below by placing an  in the correct response.
-RECALL if the trait is recessive or dominant based on the following information:
-In the pedigree, individuals I-1 and I-2 are unaffected by have affected child
 RECESSIVE  DOMINANT
-SPECIFIY if parents II-1 and II-2, who have an affected child, are carriers of that trait
 CARRIER  NOT A CARRIER
-TELL whether there is a dominant gene in the genotype of II-4
 NONE
-Individual II-1is in generation 2.
 A LEAST ONE
 TRUE  FALSE
THINK / RESPOND for each statement below,  true or false
 TRUE  FALSE -A scientist uses a pedigree to study family history
 TRUE
 TRUE
 TRUE



FALSE
FALSE
FALSE
-A pedigree traces the inheritance of a particular trait through only two generations
-In a pedigree, one who does not express the trait is represented by a darkened circle/square
-In a pedigree, a horizontal like between 2 symbols shows that these individuals are the parents
of the offspring.
Suppose both parents can roll their tongues but their son cannot.
 DRAW a pedigree showing this trait
 LABEL each symbol with the appropriate genotype