Kentucky Pharmacy Preferred Drug List Effective December 5, 2012 GENERAL DEFINITION OF TERMS st 1 Tier Medications ($) – Typically preferred generic medications. A generic medication is identified by its chemical name, while a manufacturer assigns a brand name. Also, the price of the generic medication is usually lower than that of a brand name medication. Both generic and brand name medications may require PA. nd 2 Tier Medications ($$) – Typically preferred brand medications. Preferred brand medications may have generic equivalents. Once a branded medication is available as a generic alternative, the branded medication may move to non-preferred status and the generic medication may become the preferred medication. Some Tier 2 medications may require PA. rd 3 Tier Medications ($$$) – Typically, branded medications which are not 1st or 2nd Tier. Non-preferred medications are usually available at the highest copay tier for members. Prior authorization is required for all non-preferred medications. Clinical Criteria (CC) – Due to the nature of some medications, prior authorization may be required for the medication to be covered at any copay tier. Medications that require prior authorization will require that certain clinical criteria be met. Medications may require the use of preferred medications (subject to PDL), in addition to satisfying appropriate clinical criteria, before approval (prior authorization) can be considered. If a medication requires PA, the ordering physician should contact Magellan Medicaid Administration, the plan’s pharmacy benefit administrator. Also, prescriptions exceeding such plan limitations as Quantity Limits (QL), Step Therapy (ST), Maximum Duration (MD), Age Edit (AE), in addition to those subject to Clinical Criteria (CC), will also require PA. Step Therapy (ST) – Step therapy is an electronic PA process that takes place at t he time the pharmacy submits the claim. For example, in the case of medications considered “second-line” agents, the system will look at the member’s paid claims history, and if a claim(s) for the required “first-line” medication(s) is located, the system will approve the claim. If “first-line” medication(s) are not located, the system will not approve the claim, and will return a message to the pharmacy advising that the Step Therapy protocol has not been satisfied and prior authorization is required. At that time, the pharmacy may contact the physician and request that they contact Magellan Medicaid Administration for PA. Quantity Limits (QL) – Quantity limits have been placed on medications to be consistent with the maximum dosage that the Food and Drug Administration (FDA) has approved to be both safe and effective. Medications where the quantity exceed the FDA’s maximum daily dose will require PA. Prescriptions exceeding plan limitations will require PA. Medication with Maximum Duration (MD) – Medications indicated will be available for a defined period of days per rolling year (365 days) before requiring a new or additional PA. Age Edit (AE) – Medications indicated are available for members above or below XX age without PA. Maintenance Drugs – Maintenance medications in the following classes can be processed for up to a 92 day supply and 100 units: Antianginals Antiarrhythmics Antiarthritics Antidiabetics Antihypertensives Cardiac Glycosides Digestants Diuretics Oral Contraceptives Progesterones Thyroid Preparations AE – Age Edit Rev 11/28/2012 CC – Clinical Criteria MD – Medications with Maximum Duration QL – Quantity Limit ST – Step Therapy Page 1 of 32 Kentucky Pharmacy Preferred Drug List Effective December 5, 2012 MAGELLAN MEDICAID ADMINISTRATION/KENTUCKY WEBSITE: HTTPS://KENTUCKY.MAGELLANMEDICAID.COM/ MAGELLAN MEDICAID ADMINISTRATION CLINICAL SUPPORT CENTER: PHONE 800-477-3071; FAX 800-365-8835 I. CARDIOVASCULAR Drug Class Preferred Agents ACE Inhibitors benazepril captopril enalapril fosinopril lisinopril quinapril ramipril Angiotensin Modulators Lotrel® + CCB Combinations ACEI + Diuretic Combination benazepril/HCTZ captopril/HCTZ enalapril/HCTZ lisinopril/HCTZ quinapril/HCTZ Quinaretic® Angiotensin Receptor Blockers Diovan® losartan Angiotensin Receptor Blockers + CCB (DHP) Exforge® ST Exforge HCT® AE – Age Edit Rev 11/28/2012 ST ST CC – Clinical Criteria Relative Cost Non-Preferred Agents Relative Cost of Most Agents $ $ $ $ $ $ $ Accupril® Aceon® Altace® Capoten® Lotensin® Mavik® moexipril perindopril Prinivil® trandolapril Univasc® Vasotec® Zestril® $$$ $ amlodipine/benazepril Tarka® verapamil/trandolapril $$$ $ $ $ $ $ $ Accuretic® Capozide® fosinopril HCT Lotensin HCT® moexipril/HCTZ Prinzide® Uniretic® Vaseretic® Zestoretic® $$$ $$ $ Atacand® Avapro® Benicar® Cozaar® Edarbi™ eprosartan irbesartan Micardis® Teveten® $$$ $$ $$ Azor™ Tribenzor® Twynsta® $$$ MD – Medications with Maximum Duration QL – Quantity Limit ST – Step Therapy Page 2 of 32 Kentucky Pharmacy Preferred Drug List Effective December 5, 2012 MAGELLAN MEDICAID ADMINISTRATION/KENTUCKY WEBSITE: HTTPS://KENTUCKY.MAGELLANMEDICAID.COM/ MAGELLAN MEDICAID ADMINISTRATION CLINICAL SUPPORT CENTER: PHONE 800-477-3071; FAX 800-365-8835 I. CARDIOVASCULAR Drug Class Preferred Agents ST Relative Cost Non-Preferred Agents Relative Cost of Most Agents Angiotensin Receptor Blockers + Diuretic Diovan HCT® losartan/HCTZ $ $ Atacand HCT® Avalide® Benicar HCT® Edarbyclor™ Hyzaar® irbesartan/HCTZ Micardis HCT® Teveten HCT® valsartan/HCTZ $$$ Anti-Arrhythmics, Oral amiodarone 200 mg disopyramide flecainide mexiletine procainamide propafenone quinidine gluconate quinidine sulfate quinidine sulfate CR Tikosyn® $ $ $ $ $ $ $ $ $ $$ amiodarone 400 mg Cordarone® Multaq® Norpace® Norpace® CR Pacerone® Pronestyl® propafenone SR Rythmol® Rythmol® SR Tambocor® $$$ Direct Renin Inhibitors Amturnide™ ST Tekturna® ST Tekturna HCT® ST Tekamlo® $$ $$ $$ $$ N/A Beta Blockers acebutolol atenolol betaxolol bisoprolol fumerate metoprolol succinate ER metoprolol tartrate nadolol pindolol propranolol propranolol LA sotalol timolol $ $ $ $ $ $ $ $ $ $ $ $ Betapace® Betapace® AF Bystolic® Corgard® Inderal® LA InnoPran XL® Kerlone® Levatol® Lopressor® Sectral® Sorine® Tenormin® Toprol XL® Zebeta® $$$ Beta Blockers + Diuretic atenolol/chlorthalidone bisoprolol/HCTZ metoprolol/HCTZ nadolol/endroflumethiazide propranolol/HCTZ $ $ $ $ $ Corzide® Dutoprol™ Lopressor® HCT Tenoretic® Ziac® $$$ AE – Age Edit Rev 11/28/2012 ST CC – Clinical Criteria MD – Medications with Maximum Duration QL – Quantity Limit ST – Step Therapy Page 3 of 32 Kentucky Pharmacy Preferred Drug List Effective December 5, 2012 MAGELLAN MEDICAID ADMINISTRATION/KENTUCKY WEBSITE: HTTPS://KENTUCKY.MAGELLANMEDICAID.COM/ MAGELLAN MEDICAID ADMINISTRATION CLINICAL SUPPORT CENTER: PHONE 800-477-3071; FAX 800-365-8835 I. CARDIOVASCULAR Drug Class Preferred Agents Alpha/Beta Blockers carvedilol labetalol Relative Cost Non-Preferred Agents Relative Cost of Most Agents $ $ Coreg CR® Coreg® Trandate® $$$ Calcium Channel Blockers Afeditab® CR (DHP) amlodipine felodipine ER isradipine nicardipine HCl Nifediac® CC Nifedical® XL nifedipine IR nifedipine ER/SA/XL nimodipine $ $ $ $ $ $ $ $ $ $ Adalat CC® Cardene SR® Dynacirc CR® Nimotop® nisoldipine Norvasc® Plendil® Procardia XL® Procardia® Sular® $$$ Calcium Channel Blockers diltiazem (Non-DHP) diltiazem ER verapamil verapamil ER $ $ $ $ Calan® Calan SR® Cardizem® Cardizem CD® Cardizem LA® Covera-HS® Dilacor XR® Diltia XT® Tiazac® verapamil ER PM Verelan® Verelan PM® $$$ $$ N/A Vasodilator and Nitrate Combinations BiDil® Agents for Pulmonary Hypertension Adcirca™ Letairis™ Tracleer® Ventavis® CC $$ $$ $$ $$ Revatio™ Tyvaso™ Lipotropics: Bile Acid Sequestrants cholestyramine cholestyramine light WelChol® $ $ $$ Colestid® colestipol Prevalite® Questran® Questran Light® Lipotropics: Cholesterol Absorption Inhibitors Zetia® $$ N/A Lipotropics: Fibric Acid Derivatives gemfibrozil TriCor® Trilipix™ $ $$ $$ Antara™ fenofibrate Fibricor™ Lipofen™ Lofibra® Triglide™ AE – Age Edit Rev 11/28/2012 CC – Clinical Criteria MD – Medications with Maximum Duration CC $$$ $$$ $$$ QL – Quantity Limit ST – Step Therapy Page 4 of 32 Kentucky Pharmacy Preferred Drug List Effective December 5, 2012 MAGELLAN MEDICAID ADMINISTRATION/KENTUCKY WEBSITE: HTTPS://KENTUCKY.MAGELLANMEDICAID.COM/ MAGELLAN MEDICAID ADMINISTRATION CLINICAL SUPPORT CENTER: PHONE 800-477-3071; FAX 800-365-8835 I. CARDIOVASCULAR Drug Class Preferred Agents Lipotropics: Omega-3 Fatty Acids Lovaza® ST QL Lipotropics: High Potency atorvastatin QL Statins simvastatin Lipotropics: Statins QL fluvastatin QL Lescol XL® QL lovastatin QL pravastatin Lipotropics: Statin + CCB amlodipine/atorvastatin Combination CC Relative Cost Non-Preferred Agents Relative Cost of Most Agents $$ N/A $ $ Crestor® QL Lipitor® QL Livalo® QL Vytorin™ QL Zocor® $$$ $ $$ $ $ Advicor™ QL Altoprev® QL Lescol® QL Mevacor® QL Pravachol® QL $$$ $$ Caduet® $$$ QL Lipotropics: Niacin Derivatives Niaspan® Simcor® $$ $$ Niacor® $$$ Platelet Inhibitors Aggrenox® CC Brilinta™ clopidogrel cilostazol dipyridamole Effient™ ticlopidine $$ $$ $ $ $ $$ $ Persantine® Plavix® Pletal® $$$ Anticoagulants Fragmin® fondaparinux Jantoven® Lovenox® CC Pradaxa® warfarin Xarelto® $$ $ $$ $ $$ $ $$ Arixtra® Coumadin® enoxaparin Innohep® $$$ II. GASTROINTESTINAL Drug Class Oral Anti-Emetics: Anticholinergics AE – Age Edit Rev 11/28/2012 Preferred Agents meclizine prochlorperazine promethazine Transderm-Scop Patch® trimethobenzamide CC – Clinical Criteria Relative Cost $ $ $ $$ $ Non-Preferred Agents Antivert® Phenergan® Tigan® Univert® MD – Medications with Maximum Duration Relative Cost of Most Agents $$$ QL – Quantity Limit ST – Step Therapy Page 5 of 32 Kentucky Pharmacy Preferred Drug List Effective December 5, 2012 MAGELLAN MEDICAID ADMINISTRATION/KENTUCKY WEBSITE: HTTPS://KENTUCKY.MAGELLANMEDICAID.COM/ MAGELLAN MEDICAID ADMINISTRATION CLINICAL SUPPORT CENTER: PHONE 800-477-3071; FAX 800-365-8835 II. GASTROINTESTINAL Drug Class Preferred Agents Oral Anti-Emetics: 5-HT3 ondansetron Antagonists QL QL Oral Anti-Emetics: NK-1 Antagonists Emend® Oral Anti-Emetics: Δ-9THC Derivatives dronabinol CC, QL H2 Receptor Antagonists cimetidine famotidine ranitidine QL Relative Cost Non-Preferred Agents QL Relative Cost of Most Agents $ Aloxi® QL Anzemet® QL granisetron Granisol™ QL Kytril® CC, QL Sancuso® QL Zofran® Zuplenz® $$ N/A $ Cesamet® CC, QL Marinol® $$$ $ $ $ Axid® Pepcid® nizatidine Zantac® $$$ CC, QL QL $$$ Proton Pump Inhibitors Nexium® QL omeprazole QL pantoprazole $$ $ $ Aciphex® QL Dexilant™ QL lansoprazole QL omeprazole/sodium bicarb QL Prevacid® QL Prilosec® QL Protonix® $$$ Anti-Ulcer Protectants misoprostol sucralfate $ $ Carafate® Cytotec® $$$ Combination Products for H. pylori Helidac® QL Prevpac® QL Pylera™ $$ $$ Omeclamox-Pak® $$$ Antispasmodics/ Anticholinergics atropine sulfate dicyclomine glycopyrrolate hyoscyamine methscopolamine propantheline $ $ $ $ $ $ Anaspaz® Bentyl® Cantil® chlordiazepoxide/clidinium Cuvposa® Librax® Pamine® Pamine® Forte PB-Hyos® Quadrapax® Robinul® Robinul Forte® Sal-Tropine® Scopace® $$$ AE – Age Edit Rev 11/28/2012 QL CC – Clinical Criteria MD – Medications with Maximum Duration QL – Quantity Limit ST – Step Therapy Page 6 of 32 Kentucky Pharmacy Preferred Drug List Effective December 5, 2012 MAGELLAN MEDICAID ADMINISTRATION/KENTUCKY WEBSITE: HTTPS://KENTUCKY.MAGELLANMEDICAID.COM/ MAGELLAN MEDICAID ADMINISTRATION CLINICAL SUPPORT CENTER: PHONE 800-477-3071; FAX 800-365-8835 II. GASTROINTESTINAL Drug Class Preferred Agents Relative Cost Non-Preferred Agents Relative Cost of Most Agents 5-ASA Derivatives Apriso™ Asacol® balsalazide Canasa® mesalamine enemas sfRowasa® sulfasalazine $$ $$ $ $$ $ $$ $ Asacol HD® Azulfidine® Azulfidine EN® Dipentum® Lialda™ Pentasa® Rowasa® $$$ Antidiarrheals diphenoxylate with atropine loperamide $ $ Lomotil® Motofen® paregoric $$$ $$ $ $$ $$ $ $ $ $ $$ CoLyte® with flavoring Gavilyte-C® Gavilyte-G® Gavilyte-N® GoLytely® HalfLytely-Bisacodyl Bowel Kit® Kristalose® Miralax® NuLytely® with Flavor Packs OCL® CC Relistor® Suprep® Trilyte® with Flavor Packets $$$ CC Laxatives and Cathartics Amitiza® lactulose MoviPrep® OsmoPrep® PEG 3350/Electrolyte PEG 3350/Na Sulf, Bicarb, Cl/KCl polyethylene glycol Sod Chloride/NaHCO3/KCl/PEGS Visicol® III. RESPIRATORY Drug Class Antibiotics, Inhaled Antihistamines, Minimally Sedating AE – Age Edit Rev 11/28/2012 Preferred Agents TOBI® $$ cetirizine OTC (EXCEPT chewable tablets) loratadine OTC loratadine-pseudoephedrine OTC CC – Clinical Criteria Relative Cost $ $ $ Non-Preferred Agents Cayston® $$$ ST Allegra® Allegra-D® 12 Hr Allegra-D® 24 Hr ST cetirizine syrup ST Clarinex® Clarinex-D® 12 Hr Clarinex-D® 24 Hr desloratadine ST fexofenadine fexofenadine/pseudoephedrine 12Hour fexofenadine/pseudoephedrine 24Hour ST levocetirizine Semprex D® ST Xyzal® MD – Medications with Maximum Duration Relative Cost of Most Agents QL – Quantity Limit $$$ ST – Step Therapy Page 7 of 32 Kentucky Pharmacy Preferred Drug List Effective December 5, 2012 MAGELLAN MEDICAID ADMINISTRATION/KENTUCKY WEBSITE: HTTPS://KENTUCKY.MAGELLANMEDICAID.COM/ MAGELLAN MEDICAID ADMINISTRATION CLINICAL SUPPORT CENTER: PHONE 800-477-3071; FAX 800-365-8835 III. RESPIRATORY Drug Class Preferred Agents Relative Cost Non-Preferred Agents Relative Cost of Most Agents Antihistamines, Intranasal Astepro® azelastine $$ $ Astelin® Patanase™ $$$ Anticholinergics, Intranasal ipratropium nasal spray $ Atrovent® $$$ Beta Agonists: ShortActing albuterol inhalation solution albuterol oral QL ProAir HFA® QL Proventil® HFA terbutaline $ $ $$ $$ $ levalbuterol inhalation solution QL Maxair Autohaler® QL metaproterenol inhalation solution metaproterenol oral QL Ventolin HFA® QL Xopenex® QL Xopenex HFA® Beta Agonists: LongActing Foradil® Aerolizer® QL Serevent® Diskus $$ $$ Arcapta™ QL Brovana® QL Perforomist® Beta Agonists: Combination Products Advair Diskus ® QL Advair HFA® QL Dulera® QL Symbicort® $$ $$ $$ $$ N/A COPD Agents albuterol-ipratropium inhalation QL solution QL Atrovent® HFA QL Combivent® QL Combivent Respimat® QL ipratropium inhalation solution QL Spiriva Handihaler® $ Daliresp™ QL DuoNeb® QL QL QL Corticosteroids, Inhaled Asmanex® Twisthaler AE, QL budesonide respules QL Flovent Diskus® QL Flovent HFA® QL QVAR™ Corticosteroids, Intranasal fluticasone propionate QL Nasonex® Leukotriene Modifiers montelukast CC, QL zafirlukast AE – Age Edit Rev 11/28/2012 CC – Clinical Criteria QL CC, QL QL QL $$$ QL $$$ QL $$$ $$ $$ $$ $ $$ QL $$ $ $$ $$ $$ Alvesco® QL Pulmicort Flexhaler® QL Pulmicort Respules® $ $$ Beconase AQ® QL Flonase® QL flunisolide QL Nasacort AQ® QL Omnaris™ QL Qnasl™ QL Rhinocort Aqua® QL triamcinolone QL Veramyst® QL Zetonna® $ $ Accolate® CC, QL Singulair® Zyflo CR® QL MD – Medications with Maximum Duration QL QL – Quantity Limit $$$ $$$ $$$ ST – Step Therapy Page 8 of 32 Kentucky Pharmacy Preferred Drug List Effective December 5, 2012 MAGELLAN MEDICAID ADMINISTRATION/KENTUCKY WEBSITE: HTTPS://KENTUCKY.MAGELLANMEDICAID.COM/ MAGELLAN MEDICAID ADMINISTRATION CLINICAL SUPPORT CENTER: PHONE 800-477-3071; FAX 800-365-8835 III. RESPIRATORY Drug Class Preferred Agents Epi Pen® Epi Pen® Jr. Self Injectable Epinephrine IV. Relative Cost $$ $$ Non-Preferred Agents Relative Cost of Most Agents Non-Preferred Agents Relative Cost of Most Agents N/A CENTRAL NERVOUS SYSTEM Drug Class Preferred Agents Relative Cost Alzheimer’s: Cholinesterase Inhibitors Exelon® Patch/Solution donepezil rivastigmine $$ $ $ Aricept® Aricept ODT® galantamine Exelon® galantamine ER Cognex® Razadyne® Razadyne ER® Alzheimer’s: NMDA Receptor Antagonists Namenda® $$ N/A Antialcoholic Preparations naltrexone oral Depade® ReVia® Antabuse® Campral® CC Vivitrol® $ $ $ $$ $$ $$ N/A Antianxiety Agents alprazolam IR/ER buspirone chlordiazepoxide clonazepam clorazepate diazepam tablets halazepam hydroxyzine capsules oxazepam $ $ $ $ $ $ $ $ $ diazepam liquid® Buspar® Klonopin® Librium® CC Niravam® Serax® CC Tranxene® Valium® Vistaril® CC Xanax® CC Xanax XR® AE – Age Edit Rev 11/28/2012 CC – Clinical Criteria MD – Medications with Maximum Duration $$$ CC QL – Quantity Limit $$$ ST – Step Therapy Page 9 of 32 Kentucky Pharmacy Preferred Drug List Effective December 5, 2012 MAGELLAN MEDICAID ADMINISTRATION/KENTUCKY WEBSITE: HTTPS://KENTUCKY.MAGELLANMEDICAID.COM/ MAGELLAN MEDICAID ADMINISTRATION CLINICAL SUPPORT CENTER: PHONE 800-477-3071; FAX 800-365-8835 IV. CENTRAL NERVOUS SYSTEM Drug Class Preferred Agents Antidepressants: SSRIs citalopram HBr fluoxetine HCl fluvoxamine paroxetine HCl QL sertraline ST Viibryd® Antidepressants: SNRIs QL Relative Cost Non-Preferred Agents QL Relative Cost of Most Agents $ $ $ $ $ $$ Celexa® QL escitalopram QL fluoxetine weekly QL Lexapro® Luvox® Luvox™ CR paroxetine CR Paxil® Paxil CR® Pexeva® Prozac® QL Prozac Weekly® Sarafem® QL Zoloft® Savella™ venlafaxine venlafaxine XR $$ $ $ Cymbalta® Effexor® Effexor XR® Pristiq™ venlafaxine ER tablets $$$ Antidepressants: New Generation budeprion SR bupropion SR bupropion HCl bupropion SA maprotiline mirtazapine mirtazapine rapdis nefazodone HCl trazodone $ $ $ $ $ $ $ $ $ bupropion XL budeprion XL Aplenzin™ Forfivo XL® Desyrel® Oleptro® Remeron® Remeron SolTab® Wellbutrin® Wellbutrin SR® Wellbutrin XL® $$$ Antidepressants: Tricyclics amitriptyline amoxapine clomipramine desipramine doxepin imipramine nortriptyline protriptyline Anafranil® Norpramin® Pamelor® Sinequan® $ $ $ $ $ $ $ $ $$ $$ $$ $$ Asendin® Aventyl® Elavil® Surmontil® Tofranil® Tofranil-PM® Vivactil® $$$ Antidepressants: MISC. N/A AE – Age Edit Rev 11/28/2012 CC CC – Clinical Criteria CC EMSAM® MD – Medications with Maximum Duration QL $$$ $$$ QL – Quantity Limit ST – Step Therapy Page 10 of 32 Kentucky Pharmacy Preferred Drug List Effective December 5, 2012 MAGELLAN MEDICAID ADMINISTRATION/KENTUCKY WEBSITE: HTTPS://KENTUCKY.MAGELLANMEDICAID.COM/ MAGELLAN MEDICAID ADMINISTRATION CLINICAL SUPPORT CENTER: PHONE 800-477-3071; FAX 800-365-8835 IV. CENTRAL NERVOUS SYSTEM Drug Class Preferred Agents Non-Preferred Agents Relative Cost of Most Agents $$ $ $ $ $ $ $ $$ $ $$ $ $ $ Depakene® Depakote® Depakote ER® diazepam rectal gel Dilantin® Klonopin® Mebaral® Onfi™ Stavzor™ Zarontin® $$ CC $$ $ $ $ $ $ $$ $$ $ $ Felbatol® Keppra® Keppra XR® Lamictal™ Lamictal ODT™ Lamictal XR™ levetiracetam ER Neurontin® Potiga™ tiagabine Topamax® Vimpat® Zonegran® $$ Anticonvulsants: Carbamazepine Derivatives Carbatrol® carbamazepine carbamazepine XR Equetro® oxcarbazepine $ $ $ $$ $ carbamazepine ER Tegretol® Tegretol-XR® Trileptal® $$ Antipsychotics: Typical amitriptyline/perphenazine chlorpromazine fluphenazine haloperidol loxapine Moban® Orap® perphenazine thioridazine thiothixene trifluoperazine $ $ $ $ $ $$ $$ $ $ $ $ Loxitane® Navane® $$$ Anticonvulsants: First Generation Celontin® clonazepam DiaStat® divalproex sodium divalproex sodium ER ethosuximide CC mephobarbital Peganone® CC phenobarbital Phenytek® phenytoin primidone valproic acid Relative Cost Anticonvulsants: Second Banzel® Generation felbamate Gabitril® gabapentin lamotrigine levetiracetam CC Lyrica® CC Sabril™ topiramate zonisamide AE – Age Edit Rev 11/28/2012 CC – Clinical Criteria MD – Medications with Maximum Duration QL – Quantity Limit ST – Step Therapy Page 11 of 32 Kentucky Pharmacy Preferred Drug List Effective December 5, 2012 MAGELLAN MEDICAID ADMINISTRATION/KENTUCKY WEBSITE: HTTPS://KENTUCKY.MAGELLANMEDICAID.COM/ MAGELLAN MEDICAID ADMINISTRATION CLINICAL SUPPORT CENTER: PHONE 800-477-3071; FAX 800-365-8835 IV. CENTRAL NERVOUS SYSTEM Drug Class Preferred Agents Antipsychotics: Atypical Clozaril® CC, QL Geodon® CC, QL Invega® CC, QL Latuda® CC, QL Risperdal® CC, QL Seroquel® CC, QL Zyprexa Zydis® CC, QL Zyprexa® CC, QL $ $ $ $ $ $ $ $ Haldol® Decanoate CC, QL Zyprexa® CC, QL Zyprexa® Relprevv™ $ $ olanzapine/fluoxetine $$$ $ $ $ $ $ $$ $$ $$ $$ $$ $$ $$ $$ $$ Adderall® CC, QL Concerta® CC, QL Daytrana® CC, QL Desoxyn® CC, QL Dexedrine IR/ER® CC, QL Focalin® CC, QL Kapvay™ CC, QL Methylin Solution® CC, QL mixed amphetamine salts ER methylphenidate (Generic for CC, QL Metadate CD®) methylphenidate LA (Generic Ritalin® CC, QL LA) CC, QL modafinil CC, QL Nuvigil® CC, QL Procentra™ CC, QL Provigil® CC, QL Ritalin® IR/LA/SR Symbyax® CC, QL CC, QL Rev 11/28/2012 CC – Clinical Criteria CC, QL Relative Cost of Most Agents $ $ $ $ $ $ $ $ $ $ Antihyperkinesis Agents dexmethylphenidate IR CC, QL dextroamphetamine IR/ER CC, QL methylphenidate IR/SA/SR CC, QL mixed amphetamine salts IR CC, QL Adderall XR® CC, QL Dextrostat® CC, QL Focalin XR® CC, QL Intuniv™ CC, QL Metadate CD/ER® CC, QL Methylin® CC, QL Methylin Chewable® CC, QL Methylin ER® CC, QL Strattera® CC, QL Vyvanse™ AE – Age Edit Non-Preferred Agents CC, QL Abilify® CC, QL clozapine CC, QL Fanapt™ CC, QL FazaClo ODT® CC, QL olanzapine CC, QL quetiapine CC, QL risperidone CC, QL Saphris® CC, QL Seroquel XR® CC, QL ziprasidone Antipsychotics: Injectable Abilify® CC, QL chlorpromazine CC, QL fluphenazine decanoate CC, QL Geodon® CC, QL haloperidol decanoate CC, QL Invega® Sustenna™ CC, QL olanzapine CC, QL Risperdal Consta® Atypical Antipsychotic and SSRI Comb. Relative Cost $ CC, QL MD – Medications with Maximum Duration CC, QL QL – Quantity Limit $$$ ST – Step Therapy Page 12 of 32 Kentucky Pharmacy Preferred Drug List Effective December 5, 2012 MAGELLAN MEDICAID ADMINISTRATION/KENTUCKY WEBSITE: HTTPS://KENTUCKY.MAGELLANMEDICAID.COM/ MAGELLAN MEDICAID ADMINISTRATION CLINICAL SUPPORT CENTER: PHONE 800-477-3071; FAX 800-365-8835 IV. CENTRAL NERVOUS SYSTEM Drug Class Preferred Agents QL Non-Preferred Agents QL Relative Cost of Most Agents $ Amerge® QL Alsuma® QL Axert® QL Cambia™ QL Frova™ QL Imitrex® QL Maxalt® QL Maxalt MLT® QL naratriptan QL Relpax™ QL Sumavel ™Dosepro™ QL Treximet™ QL Zomig® $$$ pramipexole Non-Ergot Dopamine Receptor Agonists ropinirole The Preferred/NonPreferred status above is applicable to use for Restless Leg Syndrome ONLY. Both Requip and Mirapex are available without prior authorization when used for Parkinson's Disease. $ $ Mirapex® Mirapex ER® Requip® Requip® XL ropinirole XL $$$ Sedative Hypnotic Agents chloral hydrate QL estazolam QL flurazepam QL temazepam 15 mg, 30 mg QL triazolam QL zolpidem $ $ $ $ $ $ Ambien® QL Ambien CR® QL Doral® CC, QL Edluar® QL Halcion® QL Intermezzo® QL Lunesta™ QL Restoril® CC, QL Rozerem® QL temazepam 22.5 mg, 7.5 mg QL Silenor® Somnote® QL Sonata® QL zaleplon QL zolpidem ER QL Zolpimist™ $$ N/A Anti-Migraine: 5-HT1 Receptor Agonists Miscellaneous CNS Agents AE – Age Edit Rev 11/28/2012 sumatriptan Relative Cost Xyrem® QL CC – Clinical Criteria QL MD – Medications with Maximum Duration QL – Quantity Limit $$$ ST – Step Therapy Page 13 of 32 Kentucky Pharmacy Preferred Drug List Effective December 5, 2012 MAGELLAN MEDICAID ADMINISTRATION/KENTUCKY WEBSITE: HTTPS://KENTUCKY.MAGELLANMEDICAID.COM/ MAGELLAN MEDICAID ADMINISTRATION CLINICAL SUPPORT CENTER: PHONE 800-477-3071; FAX 800-365-8835 IV. CENTRAL NERVOUS SYSTEM Drug Class Preferred Agents QL Skeletal Muscle Relaxants baclofen QL chlorzoxazone QL cyclobenzaprine QL dantrolene QL methocarbamol QL orphenadrine QL orphenadrine compound QL orphenadrine compound forte QL tizanidine Tobacco Cessation bupropion SR QL, MD Chantix® QL, MD nicotine gum QL, MD nicotine lozenge QL, MD nicotine transdermal system V. Relative Cost Non-Preferred Agents QL, MD $ $ $ $ $ $ $ $ $ Amrix® QL, MD carisoprodol QL, MD carisoprodol compound ER QL, MD cyclobenzaprine QL Dantrium® QL, MD Fexmid® QL, MD Flexeril® QL Gablofen® QL Lioresal® QL metaxalone QL Norflex® QL Norgesic® QL Robaxin® QL Skelaxin® QL, MD Soma® QL tizanidine capsules QL Zanaflex® QL, MD Relative Cost of Most Agents $$$ QL, MD Commit Lozenge® QL, MD Nicoderm CQ® QL, MD Nicorette® QL, MD Nicorette Mini Lozenge® QL, MD Nicotrol® Inhaler QL, MD Nicotrol® NS QL, MD Zyban® ANALGESICS Drug Class Narcotic Agonist/ Antagonists AE – Age Edit Rev 11/28/2012 Preferred Agents butorphanol NS pentazocine/APAP pentazocine/naloxone CC – Clinical Criteria Relative Cost $ $ $ Non-Preferred Agents Stadol NS® Talacen® Talwin® Talwin NX® Zanaflex® MD – Medications with Maximum Duration Relative Cost of Most Agents $$$ QL – Quantity Limit ST – Step Therapy Page 14 of 32 Kentucky Pharmacy Preferred Drug List Effective December 5, 2012 MAGELLAN MEDICAID ADMINISTRATION/KENTUCKY WEBSITE: HTTPS://KENTUCKY.MAGELLANMEDICAID.COM/ MAGELLAN MEDICAID ADMINISTRATION CLINICAL SUPPORT CENTER: PHONE 800-477-3071; FAX 800-365-8835 V. ANALGESICS Drug Class Preferred Agents Narcotics: Short-Acting AE – Age Edit Rev 11/28/2012 butalbital compound/codeine MD codeine/APAP dihydrocodeine bitartrate/APAP/caffeine MD hydrocodone/APAP hydrocodone/ibuprofen hydromorphone meperidine morphine IR oxycodone MD oxycodone/APAP oxycodone/ibuprofen oxymorphone IR tramadol CC – Clinical Criteria Relative Cost CC $ $ $ $ $ $ $ $ $ $ $ $ $ Non-Preferred Agents Relative Cost of Most Agents All branded short-acting narcotics and $$$ narcotic combinations codeine Capital® Demerol® Dilaudid® Endodan® Hycet® Ibudone™ levorphanol Margesic H® Maxidone® Norco® Nucynta™ Opana® Oxecta® MD oxycodone/ASA Primlev® Reprexain™ Rybix™ ODT Synalgos DC® tramadolAPAP Trezix® Ultracet® Ultram® Xodol® Xolox® Zamicet™ Zolvit™ MD – Medications with Maximum Duration QL – Quantity Limit ST – Step Therapy Page 15 of 32 Kentucky Pharmacy Preferred Drug List Effective December 5, 2012 MAGELLAN MEDICAID ADMINISTRATION/KENTUCKY WEBSITE: HTTPS://KENTUCKY.MAGELLANMEDICAID.COM/ MAGELLAN MEDICAID ADMINISTRATION CLINICAL SUPPORT CENTER: PHONE 800-477-3071; FAX 800-365-8835 V. ANALGESICS Drug Class Preferred Agents CC, QL Narcotics: Long-Acting fentanyl transdermal QL Kadian® QL methadone QL morphine sulfate SA Narcotics: Fentanyl Buccal Products N/A AE – Age Edit Rev 11/28/2012 CC – Clinical Criteria Relative Cost $ $$ $ $ Non-Preferred Agents QL Avinza™ CC, QL Butrans™ QL ConZip™ QL Dolophine® CC, QL Duragesic® QL Embeda™ QL Exalgo™ methadone concentrate morphine sulfate SA (Generic QL Kadian®) QL MS Contin® QL Nucynta® ER QL Opana ER® QL Oramorph® SR QL oxycodone SR QL OxyContin® QL oxymorphone ER QL Ryzolt™ QL tramadol ER QL Ultram® ER fentanyl citrate lollipop CC, QL Abstral® CC, QL Actiq® CC, QL Fentora® CC, QL Onsolis™ MD – Medications with Maximum Duration CC, QL QL – Quantity Limit Relative Cost of Most Agents $$$ $$$ ST – Step Therapy Page 16 of 32 Kentucky Pharmacy Preferred Drug List Effective December 5, 2012 MAGELLAN MEDICAID ADMINISTRATION/KENTUCKY WEBSITE: HTTPS://KENTUCKY.MAGELLANMEDICAID.COM/ MAGELLAN MEDICAID ADMINISTRATION CLINICAL SUPPORT CENTER: PHONE 800-477-3071; FAX 800-365-8835 V. ANALGESICS Drug Class Non-Steroidal AntiInflammatory Drugs VI. Preferred Agents Celebrex® diclofenac potassium etodolac flurbiprofen ibuprofen indomethacin ketoprofen QL ketorolac tromethamine meloxicam tablets naproxen sodium naproxen tablets piroxicam sulindac Relative Cost $$ $ $ $ $ $ $ $ $ $ $ $ $ Non-Preferred Agents Anaprox® Anaprox® DS Ansaid® Arthrotec® Cataflam® Clinoril® Daypro® diclofenac sodium diclofenac SR diflunisal CC Duexis® etodolac SR Feldene® fenoprofen CC Flector® Indocin® indomethacin ER ketoprofen ER meclofenamate mefenamic acid meloxicam suspension Mobic® nabumetone Nalfon® Naprelan® EC naproxen suspension naproxen EC oxaprozin CC Pennsaid® Ponstel® CC Sprix™ tolmetin QL Vimovo™ CC Voltaren® Gel Voltaren® XR Zipsor™ Relative Cost of Most Agents $$$ ANTI-INFECTIVES Drug Class Antibiotics: st Cephalosporins 1 Generation AE – Age Edit Rev 11/28/2012 Preferred Agents cefadroxil cephalexin CC – Clinical Criteria Relative Cost $ $ Non-Preferred Agents Duricef® Keflex® MD – Medications with Maximum Duration Relative Cost of Most Agents $$$ QL – Quantity Limit ST – Step Therapy Page 17 of 32 Kentucky Pharmacy Preferred Drug List Effective December 5, 2012 MAGELLAN MEDICAID ADMINISTRATION/KENTUCKY WEBSITE: HTTPS://KENTUCKY.MAGELLANMEDICAID.COM/ MAGELLAN MEDICAID ADMINISTRATION CLINICAL SUPPORT CENTER: PHONE 800-477-3071; FAX 800-365-8835 VI. ANTI-INFECTIVES Drug Class Preferred Agents Relative Cost Non-Preferred Agents Relative Cost of Most Agents Antibiotics: nd Cephalosporins 2 Generation cefaclor cefprozil cefuroxime $ $ $ Ceclor® cefaclor ER Ceftin® Cefzil® Raniclor™ $$$ Antibiotics: rd Cephalosporins 3 Generation cefdinir cefditoren cefpodoxime Suprax® $ $ $ $$ Cedax® Omnicef® Spectracef® Suprax® chewable tablets Vantin® $$$ Antibiotics: GI Alinia® tablets metronidazole tablets vancomycin $$ $ $ Alinia® suspension Dificid® Flagyl® Flagyl® ER metronidazole capsules neomycin Neo-Fradin® Tindamax® tinidazole CC, QL Xifaxan® Vancocin® $$$ Antibiotics: Ketolides Ketek® $$ N/A Antibiotics: Macrolides azithromycin azithromycin pack azithromycin suspension clarithromycin clarithromycin suspension erythromycin erythromycin liquid erythromycin suspension erythromycin tablet ER/SA $ $ $ $ $ $ $ $ $ clarithromycin ER Biaxin® Biaxin® Suspension Biaxin XL® Zithromax® CC Dificid™ Zithromax® Pack Zithromax® Suspension Zmax® Antibiotics: Oxazolidinones Zyvox® $$ N/A Antibiotics: Penicillins amoxicillin amoxicillin/clavulanate amoxicillin/clavulanate ES-600 ampicillin dicloxacillin penicillin V $ $ $ $ $ $ All branded penicillins amoxicillin/clavulanate XR Amoxil® Amoclan® Augmentin® Augmentin ES-600® Augmentin XR® Moxatag™ Trimox® Veetids® AE – Age Edit Rev 11/28/2012 CC, QL CC, QL CC – Clinical Criteria MD – Medications with Maximum Duration QL – Quantity Limit $$$ $$$ ST – Step Therapy Page 18 of 32 Kentucky Pharmacy Preferred Drug List Effective December 5, 2012 MAGELLAN MEDICAID ADMINISTRATION/KENTUCKY WEBSITE: HTTPS://KENTUCKY.MAGELLANMEDICAID.COM/ MAGELLAN MEDICAID ADMINISTRATION CLINICAL SUPPORT CENTER: PHONE 800-477-3071; FAX 800-365-8835 VI. ANTI-INFECTIVES Drug Class Preferred Agents Antibiotics: Quinolones Non-Preferred Agents Relative Cost of Most Agents $ $ Avelox® ciprofloxacin ER Cipro® Cipro XR® Factive® Levaquin® levofloxacin solution Noroxin® ofloxacin Antibiotics: Tetracyclines demeclocycline doxycycline minocycline tetracycline $ $ $ $ All branded tetracyclines $$$ Adoxa®/Adoxa®Pak Adoxa® CK/Adoxa®TT Declomycin® Doryx® Dynacin® Minocin®/Minocin® Convenience Pack Monodox® Morgidox® Myrac® Nutri Dox® AE Oracea® MD Solodyn® Sumycin® Vibra-Tabs® Vibramycin® Antifungals: Oral clotrimazole fluconazole flucytosine griseofulvin CC itraconazole ketoconazole nystatin terbinafine Gris-Peg® Noxafil® voriconazole $ $ $ $ $ $ $ $ $ $$ $$ Ancobon® Diflucan® Diflucan® Grifulvin V® griseofulvin ultramicrosize Lamisil® Mycelex Troche® Mycostatin® Nizoral® Oravig® Sporanox® Vfend® $$$ Antivirals: Herpes acyclovir valacyclovir $ $ famciclovir Famvir® Valtrex® Zovirax® $$$ Antivirals: Influenza amantadine rimantadine Relenza® QL Tamiflu® $ $ $$ $$ Flumadine® $$$ AE – Age Edit Rev 11/28/2012 ciprofloxacin levofloxacin tablets Relative Cost CC – Clinical Criteria MD – Medications with Maximum Duration QL – Quantity Limit $$$ ST – Step Therapy Page 19 of 32 Kentucky Pharmacy Preferred Drug List Effective December 5, 2012 MAGELLAN MEDICAID ADMINISTRATION/KENTUCKY WEBSITE: HTTPS://KENTUCKY.MAGELLANMEDICAID.COM/ MAGELLAN MEDICAID ADMINISTRATION CLINICAL SUPPORT CENTER: PHONE 800-477-3071; FAX 800-365-8835 VI. ANTI-INFECTIVES Drug Class Preferred Agents Relative Cost Non-Preferred Agents Anti-Infective: Sulfonamides, Folate Antagonist sulfadiazine trimethoprim trimethoprim/sulfamethoxazole $ $ $ Bactrim® Bactrim DS® Primsol® Septra® Septra DS® Sulfatrim® Anti-Infectives: Hepatitis B Baraclude® Epivir-HBV® Hepsera® Tyzeka® $$ $$ $$ $$ N/A Hepatitis C: Oral Protease Incivek™ CC, QL Inhibitors Victrelis™ $$ $$ N/A CC, QL $$ $$ $$ $$ Infergen $$ $ Copegus® CC Rebetol® CC Ribasphere™ 600 mg CC RibaPak™ CC ribavirin capsules CC, QL Hepatitis C: Interferons PEGASYS® CC, QL PEGASYS ProClick® CC, QL PEGIntron™ CC, QL PEGIntron Redipen™ Hepatitis C: Ribavirins Ribasphere™ 400 mg CC ribavirin tablets VII. CC Relative Cost of Most Agents $$$ ® CC, QL CC $$ $$$ ENDOCRINE AND METABOLIC AGENTS Drug Class Diabetes: Injectable Insulins Preferred Agents Lantus® Vials Levemir® Novolin N® Vials Novolin R® Vials Novolin 70/30® Vials Novolog® Novolog Mix 70/30® Diabetes: Amylin Analog N/A AE – Age Edit Rev 11/28/2012 CC – Clinical Criteria Relative Cost $$ $$ $$ $$ $$ $$ $$ Non-Preferred Agents Apidra® Humalog® Humalog 50/50® Pen/KwikPen Humalog 75/25® Humulin N® Humulin R® Humulin 70/30® CC Lantus Solostar® Relion N® Relion R® Relion 70/30® Symlin® MD – Medications with Maximum Duration ST Relative Cost of Most Agents $$$ $$$ QL – Quantity Limit ST – Step Therapy Page 20 of 32 Kentucky Pharmacy Preferred Drug List Effective December 5, 2012 MAGELLAN MEDICAID ADMINISTRATION/KENTUCKY WEBSITE: HTTPS://KENTUCKY.MAGELLANMEDICAID.COM/ MAGELLAN MEDICAID ADMINISTRATION CLINICAL SUPPORT CENTER: PHONE 800-477-3071; FAX 800-365-8835 VII. ENDOCRINE AND METABOLIC AGENTS Drug Class Preferred Agents ST, QL Diabetes: DPP-4 Inhibitors Januvia® ST, QL Janumet® ST, QL Janumet® XR ST, QL Jentadueto™ ST, QL Juvisync™ ST, QL Kombiglyze™ XR ST, QL Onglyza™ ST, QL Tradjenta™ Diabetes: Incretin Mimetic Byetta® Diabetes: AlphaGlucosidase Inhibitors Relative Cost Non-Preferred Agents Relative Cost of Most Agents $$ $$ $$ $$ $$ $$ $$ $$ N/A $$ Bydureon® Victoza® $$$ acarbose Glyset® $ $$ Precose® $$$ Diabetes: Biguanides metformin metformin ER $ $ Fortamet® Glucophage® Glucophage XR® Glumetza® Riomet® $$$ Diabetes: Meglitinides nateglinide Prandin® $ $$ Prandimet® Starlix® $$$ Diabetes: Sulfonylureas and Combinations chlorpropamide glimepiride glipizide glipizide ER/XL glipizide/metformin glyburide glyburide micronized glyburide/metformin tolazamide tolbutamide $ $ $ $ $ $ $ $ $ $ Amaryl® Diabeta® Glucotrol® Glucotrol XL® Glucovance® Glynase PresTab® Metaglip® Micronase® $$$ Diabetes: Thiazolidinediones Actos® QL Avandia® $$ $$ pioglitazone Diabetes: Thiazolidinedione Combination ACTOplus Met® QL Avandamet® QL DuetAct® $$ $$ $$ Avandaryl® QL ActoPlus Met XR® pioglitazone/metformin Growth Hormones Genotropin® CC Norditropin® CC Norditropin Flexpro® CC Saizen® $$ $$ $$ $$ Humatrope® CC Nutropin® CC Nutropin AQ® CC Omnitrope® CC Serostim® CC Tev-Tropin® CC Zorbtive® AE – Age Edit Rev 11/28/2012 ST QL CC CC – Clinical Criteria QL QL MD – Medications with Maximum Duration CC QL – Quantity Limit $$$ $$$ ST – Step Therapy Page 21 of 32 Kentucky Pharmacy Preferred Drug List Effective December 5, 2012 MAGELLAN MEDICAID ADMINISTRATION/KENTUCKY WEBSITE: HTTPS://KENTUCKY.MAGELLANMEDICAID.COM/ MAGELLAN MEDICAID ADMINISTRATION CLINICAL SUPPORT CENTER: PHONE 800-477-3071; FAX 800-365-8835 VII. ENDOCRINE AND METABOLIC AGENTS Drug Class Preferred Agents Bone: Bisphosphonates alendronate Bone: Calcitonin QL Relative Cost Non-Preferred Agents QL Relative Cost of Most Agents $ Actonel® QL Actonel with Calcium® QL Atelvia® QL Boniva® QL Binosto® QL Boniva I.V.® Didronel® etidronate QL Fosamax® QL Fosamax Plus D® QL ibandronate Reclast® QL Skelid® QL $$$ Miacalcin® calcitonin-salmon $$ $ Fortical® $$$ Progestins for Cachexia megestrol acetate $ Megace® Megace® ES $$$ Pancreatic Enzymes Creon® pancrelipase Zenpep® $$ $ $$ Pancreaze™ $$$ Androgenic Agents Androderm® Androgel® $$ $$ Axiron® Fortesta® Testim® $$$ Oral Steroids cortisone dexamethasone budesonide hydrocortisone methylprednisolone prednisolone prednisolone sodium phosphate prednisone Zema-Pak® $ $ $ $ $ $ $ $ $$ Baycadron® Celestone® Cortef® DexPak® DexPak JR® Entocort EC® Millipred® AE Orapred ® AE Orapred ODT® Pediapred® Prelone® Veripred 20® $$$ AE – Age Edit Rev 11/28/2012 CC – Clinical Criteria MD – Medications with Maximum Duration QL – Quantity Limit ST – Step Therapy Page 22 of 32 Kentucky Pharmacy Preferred Drug List Effective December 5, 2012 MAGELLAN MEDICAID ADMINISTRATION/KENTUCKY WEBSITE: HTTPS://KENTUCKY.MAGELLANMEDICAID.COM/ MAGELLAN MEDICAID ADMINISTRATION CLINICAL SUPPORT CENTER: PHONE 800-477-3071; FAX 800-365-8835 VIII. IMMUNOLOGIC AGENTS Drug Class Preferred Agents CC, QL Relative Cost Non-Preferred Agents CC, QL Relative Cost of Most Agents Immunomodulators Cimzia® CC QL Enbrel® CC, QL Humira® $$ $$ $$ Actemra® CC, QL Amevive® CC, QL Kineret® CC, QL Orencia® CC, QL Remicade® CC, QL Simponi™ CC, QL Stelara™ $$$ Topical Immunomodulators Elidel® $$ Protopic® $$$ Multiple Sclerosis Agents Avonex® QL Avonex Administration Pack® QL Betaseron® QL Copaxone® QL Rebif® $$ $$ $$ $$ $$ Ampyra™ QL Extavia® QL Gilenya™ QL, CC $$$ Immunosuppressants $ $ $$ $ $$ $$ $ Azasan® Cellcept® Hecoria® Imuran® Neoral® Prograf® Sandimmune® Zortress® $$$ QL IX. azathioprine cyclosporine Gengraf® mycophenolate mofetil Myfortic® Rapamune® tacrolimus BLOOD MODIFIERS Drug Class Preferred Agents CC Hematopoietic Agents Aranesp® CC Epogen® CC Procrit® Thrombopoiesis Stimulating Agents Relative Cost Non-Preferred Agents $$ $$ $$ Omontys® Neumega® CC Promacta® $$ $$ Nplate™ Antihyperuricemics allopurinol probenecid probenecid/colchicine $ $ $ Phosphate Binders calcium acetate Fosrenol® Renagel® $ $$ $$ AE – Age Edit Rev 11/28/2012 CC CC – Clinical Criteria CC Relative Cost of Most Agents $$$ CC $$$ Colcrys™ CC Uloric® Zyloprim® CC $$$ Eliphos® PhosLo® Phoslyra™ Renvela™ $$$ MD – Medications with Maximum Duration QL – Quantity Limit ST – Step Therapy Page 23 of 32 Kentucky Pharmacy Preferred Drug List Effective December 5, 2012 MAGELLAN MEDICAID ADMINISTRATION/KENTUCKY WEBSITE: HTTPS://KENTUCKY.MAGELLANMEDICAID.COM/ MAGELLAN MEDICAID ADMINISTRATION CLINICAL SUPPORT CENTER: PHONE 800-477-3071; FAX 800-365-8835 X. OPHTHALMICS Drug Class Preferred Agents Relative Cost Non-Preferred Agents Relative Cost of Most Agents Ophthalmic Antivirals trifluridine Viroptic® Zirgan™ $ $$ $$ N/A Ophthalmic Antifungals Natacyn® $$ N/A Ophthalmic Antibiotics, Quinolone ciprofloxacin ophthalmic Moxeza™ ofloxacin Vigamox® $ $$ $ $$ Besivance™ Ciloxan® CC Iquix® levofloxacin Ocuflox® Quixin® Zymar® Zymaxid™ Ophthalmic Antibiotics, Macrolides erythromycin 0.5% ointment $ AzaSite® Romycin® $$$ Ophthalmic Antibiotics, Non-Quinolone bacitracin bacitracin/poly B gentamicin neomycin/bac/poly B neomycin/poly B/HC neomycin/bac/poly B/HC neomycin/poly B/dexamethasone neomycin/poly B/gramicidin polymyxin B/TMP sulfacetamide sodium tobramycin tobramycin/dexamethasone Blephamide® Pred-G® TobraDex® Ointment Zylet® $ $ $ $ $ $ $ $ $ $ $ $ $$ $$ $$ $$ AK-Poly Bac® AK-Trol® Bleph-10® Gentak® Gentasol® Maxitrol® Methadex® Neocidin® Neosporin® Polydex® Polytrim® sulfacetamide/prednisolone Sulfamide® Tobrex® TobraDex® Suspension TobraDex® ST $$$ Ophthalmic Antihistamines Alaway OTC® Pataday™ Zaditor OTC® $$ $$ $$ azelastine Bepreve™ Elestat™ Emadine® epinastine Lastacaft™ Optivar® Patanol® $$$ AE – Age Edit Rev 11/28/2012 CC – Clinical Criteria $$$ CC MD – Medications with Maximum Duration QL – Quantity Limit ST – Step Therapy Page 24 of 32 Kentucky Pharmacy Preferred Drug List Effective December 5, 2012 MAGELLAN MEDICAID ADMINISTRATION/KENTUCKY WEBSITE: HTTPS://KENTUCKY.MAGELLANMEDICAID.COM/ MAGELLAN MEDICAID ADMINISTRATION CLINICAL SUPPORT CENTER: PHONE 800-477-3071; FAX 800-365-8835 X. OPHTHALMICS Drug Class Preferred Agents Relative Cost Non-Preferred Agents Relative Cost of Most Agents Ophthalmic Beta Blockers betaxolol HCl carteolol HCl levobunolol metipranolol timolol maleate Betimol® Betoptic S® Combigan® Istalol® $ $ $ $ $ $$ $$ $$ $$ Betagan® OptiPranolol® Timoptic® Timoptic XE® $$$ Ophthalmic Carbonic Anhydrase Inhibitors dorzolamide dorzolamide/timolol Azopt® $ $ $$ Cosopt® Cosopt® PF Trusopt® $$$ Ophthalmic Decongestants phenylephrine tetrahydrozoline $ $ AK-Con® AK-Dilate® Mydfrin® $$$ Ophthalmic Mast Cell Stabilizers cromolyn sodium $ Alamast® Alocril® Alomide® $$$ Ophthalmic Mydriatics & atropine Mydriatic Combos cyclopentolate Isopto Hyoscine® tropicamide $ $ $$ $ AK-Pentolate® Cyclogyl® Cyclomydril® Isopto Atropine® Isopto Homatropine® Mydriacyl® Paremyd® Tropicacyl® $$$ Ophthalmic NSAIDs diclofenac flurbiprofen ketorolac $ $ $ Acular® Acular LS® Acuvail™ Bromday® bromfenac Nevanac® Ocufen® Voltaren® $$$ Ophthalmic Prostaglandin Agonists latanoprost $ Lumigan® QL Travatan Z® QL Xalatan® QL Zioptan® AE – Age Edit Rev 11/28/2012 QL CC – Clinical Criteria MD – Medications with Maximum Duration QL QL – Quantity Limit $$$ ST – Step Therapy Page 25 of 32 Kentucky Pharmacy Preferred Drug List Effective December 5, 2012 MAGELLAN MEDICAID ADMINISTRATION/KENTUCKY WEBSITE: HTTPS://KENTUCKY.MAGELLANMEDICAID.COM/ MAGELLAN MEDICAID ADMINISTRATION CLINICAL SUPPORT CENTER: PHONE 800-477-3071; FAX 800-365-8835 X. OPHTHALMICS Drug Class Preferred Agents Relative Cost Non-Preferred Agents Relative Cost of Most Agents Ophthalmic AntiInflammatory Steroids dexamethasone fluorometholone prednisolone acetate prednisolone sodium phosphate Flarex® Lotemax® Maxidex® Vexol® $ $ $ $ $$ $$ $$ $$ Alrex® Durezol™ FML® FML Forte® FML S.O.P.® Omnipred™ Pred Forte® Pred Mild® Retisert™ Triesence® $$$ Ophthalmic Glaucoma Direct Acting Miotics pilocarpine $ Isopto Carpine® Pilopine HS® $$$ Ophthalmic Sympathomimetics apraclonidine brimonidine tartrate $ $ Alphagan P® Iopidine® $$$ Ophthalmic Immunomodulators Restasis® $$ N/A XI. ST OTICS Drug Class Preferred Agents Relative Cost Non-Preferred Agents Relative Cost of Most Agents Otic: Quinolone Antibiotics ofloxacin otic CiproDex® $ $$ Cetraxal™ Cipro HC® $$$ Otic: Anti-Infective & Anesthetic acetic acid acetic acid in aluminum acetate antipyrine/benzocaine pramoxine/hydrocortisone $ $ $ $ acetic acid/hydrocortisone Neotic® Otic Care® Otozin™ Pramotic® HC PR Otic® Tregan® Vosol® HC Zinotic® Zinotic® ES $$$ Coly-mycin® S Cortisporin® Cortisporin® – TC Cortomycin® fluocinolone otic $$$ hydrocortisone/neomycin/polymyxinB $ Otic: Steroid and Antibiotic Combinations AE – Age Edit Rev 11/28/2012 CC – Clinical Criteria MD – Medications with Maximum Duration QL – Quantity Limit ST – Step Therapy Page 26 of 32 Kentucky Pharmacy Preferred Drug List Effective December 5, 2012 MAGELLAN MEDICAID ADMINISTRATION/KENTUCKY WEBSITE: HTTPS://KENTUCKY.MAGELLANMEDICAID.COM/ MAGELLAN MEDICAID ADMINISTRATION CLINICAL SUPPORT CENTER: PHONE 800-477-3071; FAX 800-365-8835 XII. RENAL AND GENITOURINARY Drug Class Preferred Agents Alpha Blockers for BPH alfuzosin doxazosin tamsulosin terazosin Androgen Hormone Inhibitors finasteride Urinary Tract Antispasmodics flavoxate QL oxybutynin QL Toviaz™ QL VESIcare® XIII. CC QL Relative Cost Non-Preferred Agents $ $ $ $ Cardura® Cardura XL® Flomax® Hytrin® Rapaflo™ Uroxatral® $ Avodart® CC Jalyn® CC Proscar® $ $ $$ $$ Detrol® QL Detrol LA® QL Ditropan XL® QL Enablex® CC, QL Gelnique™ QL oxybutynin ER QL Oxytrol™ QL Sanctura® QL Sanctura XR® QL tolterodine QL trospium Relative Cost of Most Agents $$$ CC $$$ QL $$$ DERMATOLOGICS Drug Class Preferred Agents Relative Cost Non-Preferred Agents Relative Cost of Most Agents Dermatologics: AntiVirals Abreva® Zovirax® ointment $$ $$ Denavir® cream Zovirax® cream Xerese® $$$ Dermatologics: Antiseborrheic Agents selenium sulfide Carmol® $ $$ Ovace® Ovace Plus® Seb-Prev® Selenos® Selseb® Scalp Treatment Kit® $$$ $ $ $ Altabax™ Bactroban® Centany® $$$ Dermatologics: Antibiotic bacitracin ointment Agents bacitracin zinc ointment bacitracin/neomycin/polymyxin B ointment bacitracin/neomycin/polymyxin B/ pramoxine ointment bacitracin/polymyxin B ointment gentamicin 0.1% cream, ointment mupirocin neomycin/polymyxin/pramoxine AE – Age Edit Rev 11/28/2012 CC – Clinical Criteria $ $ $ $ $ MD – Medications with Maximum Duration QL – Quantity Limit ST – Step Therapy Page 27 of 32 Kentucky Pharmacy Preferred Drug List Effective December 5, 2012 MAGELLAN MEDICAID ADMINISTRATION/KENTUCKY WEBSITE: HTTPS://KENTUCKY.MAGELLANMEDICAID.COM/ MAGELLAN MEDICAID ADMINISTRATION CLINICAL SUPPORT CENTER: PHONE 800-477-3071; FAX 800-365-8835 XIII. DERMATOLOGICS Drug Class Preferred Agents Relative Cost Non-Preferred Agents Relative Cost of Most Agents Dermatologics: Antiparasitics, Topical Eurax® malathion permethrin 5% cream $$ $ $ Acticin® Elimite® lindane Ovide® Natroba™ spinosad Ulesfia™ Miscellaneous Topical Treatments for Acne benzoyl peroxide benzoyl peroxide/clindamycin benzoyl peroxide/erythromycin clindamycin erythromycin salicylic acid sodium sulfacetamide sodium sulfacetamide/sulfur BenzaClin® Benzamycin® Lavoclen™ $ $ $ $ $ $ $ $ $$ $$ $ All brand benzoyl peroxide products $$$ All brand benzoyl peroxide/clindamycin products All brand benzoyl peroxide/erythromycin products All brand clindamycin products All brand erythromycin products All brand salicylic acid products All brand sodium sulfacetamide products All brand sodium sulfacetamide/sulfur products Acanya™ Aczone™ Avar® Azelex® Benprox® Benzac® AC/W BenzaClin CareKit® Benzashave® Benziq® benzoyl peroxide/urea BP® 10 BPO® Brevoxyl® Cerisa® Clarifoam® EF Claris® Clenia® Cllinac BPO® Clindacin Pac® Clinda-Derm® Clindagel® Clindamax® ClindaReach™ Desquam-X® Duac CS®QL Emgel® Evoclin™ AE – Age Edit Rev 11/28/2012 CC – Clinical Criteria MD – Medications with Maximum Duration $$$ QL – Quantity Limit ST – Step Therapy Page 28 of 32 Kentucky Pharmacy Preferred Drug List Effective December 5, 2012 MAGELLAN MEDICAID ADMINISTRATION/KENTUCKY WEBSITE: HTTPS://KENTUCKY.MAGELLANMEDICAID.COM/ MAGELLAN MEDICAID ADMINISTRATION CLINICAL SUPPORT CENTER: PHONE 800-477-3071; FAX 800-365-8835 XIII. DERMATOLOGICS Drug Class Preferred Agents Relative Cost Non-Preferred Agents Relative Cost of Most Agents Finacea®/Finacea Plus® Inova™ Klaron® NuOx® Oscion® Pacnex® Plexion® Prascion® RA Rosac® Rosaderm® Rosanil® Rosula® CLK Salkera® Foam Salacyn® Salvax® sodium sulfacetamide/sulfur/ urea/meradimate/titanium Suphera® Sumadan® Sumaxin® Topisulf® Triaz® Zacare™ Zaclir® Zetacet® Zoderm® AE – Age Edit Rev 11/28/2012 CC – Clinical Criteria MD – Medications with Maximum Duration QL – Quantity Limit ST – Step Therapy Page 29 of 32 Kentucky Pharmacy Preferred Drug List Effective December 5, 2012 MAGELLAN MEDICAID ADMINISTRATION/KENTUCKY WEBSITE: HTTPS://KENTUCKY.MAGELLANMEDICAID.COM/ MAGELLAN MEDICAID ADMINISTRATION CLINICAL SUPPORT CENTER: PHONE 800-477-3071; FAX 800-365-8835 XIII. DERMATOLOGICS Drug Class Preferred Agents Relative Cost Non-Preferred Agents Dermatologics: Antifungal Agents clotrimazole econazole ketoconazole shampoo nystatin cream/ointment nystatin/triamcinolone $ $ $ $ $ ciclopirox ciclopirox/nail lacquer remover Ciclodan Kit® CNL8™ Nail Kit clotrimazole/betamethasone Ertazczo® Exelderm® Extina® ketoconazole cream Ketodan® Kuric® Lamisil® Loprox® Lotrimin® Lotrisone® Mentax® Monistat-Derm® Myconel® Mycostatin® Naftin® Nizoral® Nyamyc® nystatin powder Nystop® Oxistat® Pedi-Dri® Pediaderm AF® Pedipirox-4 Nail® Penlac® Spectazole® CC Vusion® Xolegel® Xolegel Corepack® Xolegel Duo® Dermatologics: Oral Retinoids Amnesteem® Claravis® Soriatane® CK Sotret® $$ $$ $$ $$ N/A AE – Age Edit Rev 11/28/2012 CC – Clinical Criteria MD – Medications with Maximum Duration QL – Quantity Limit Relative Cost of Most Agents $$$ ST – Step Therapy Page 30 of 32 Kentucky Pharmacy Preferred Drug List Effective December 5, 2012 MAGELLAN MEDICAID ADMINISTRATION/KENTUCKY WEBSITE: HTTPS://KENTUCKY.MAGELLANMEDICAID.COM/ MAGELLAN MEDICAID ADMINISTRATION CLINICAL SUPPORT CENTER: PHONE 800-477-3071; FAX 800-365-8835 XIII. DERMATOLOGICS Drug Class Preferred Agents Relative Cost Non-Preferred Agents Relative Cost of Most Agents Dermatologics: Topical Retinoids adapalene Retin-A Micro® tretinoin $ $$ $ Atralin™ Avita® Differin® Epiduo™ Retin-A® Retin-A Micro® Pump CC Tazorac® Veltirn™ Ziana™ $$$ Dermatologics: Topical Steroids alclometasone amcinonide betamethasone dipropionate betamethasone valerate clobetasol propionate desonide fluocinolone fluocinonide fluticasone halobetasol hydrocortisone hydrocortisone butyrate hydrocortisone valerate mometasone nystatin-triamcinolone prednicarbate triamcinolone $ $ $ $ $ $ $ $ $ $ $ $ $ $ $ $ $ Aclovate® ApexiCon®/ApexiCon E® Beta-Val® Capex® Shampoo Clobeta + Plus® Clobex® Cloderm® Cordran® Tape Cormax® clotrimazole/betamethasone Cutivate® Derma-Smoothe/FS® Dermatop® Desowen® desoximetasone diflorasone diacetate Diprolene®/Diprolene AF® Elocon® fluocinolone scalp oil Halog® Halonate® Ketocon + Plus® Lokara® Lotrisone® Luxiq® Momexin™ Olux®/Olux-E® Olux-Olux E® Complete Pack Pandel® Temovate® Texacort® Topicort® Topicort LP® Ultravate® Vanos™ Verdeso™ Westcort® $$$ AE – Age Edit Rev 11/28/2012 CC – Clinical Criteria MD – Medications with Maximum Duration QL – Quantity Limit ST – Step Therapy Page 31 of 32 Kentucky Pharmacy Preferred Drug List Effective December 5, 2012 MAGELLAN MEDICAID ADMINISTRATION/KENTUCKY WEBSITE: HTTPS://KENTUCKY.MAGELLANMEDICAID.COM/ MAGELLAN MEDICAID ADMINISTRATION CLINICAL SUPPORT CENTER: PHONE 800-477-3071; FAX 800-365-8835 XIII. DERMATOLOGICS Drug Class Preferred Agents Dermatologics: Topical Agents for Psoriasis XIV. calcipotriene scalp solution calcipotriene ointment Dovonex® cream Relative Cost $ $ $ Non-Preferred Agents Calcitriol calcipotriene cream Dovonex® solution/ointment Psoriatec® Sorilux® Taclonex® CC Tazorac® Vectical™ Zithranol® Relative Cost of Most Agents $$$ ANTINEOPLASTIC AGENTS Drug Class Preferred Agents Oral Oncology Agents AE – Age Edit Rev 11/28/2012 QL Caprelsa® CC, QL Erivedge™ QL Gleevec® CC, QL Inlyta® QL Iressa® CC, QL Jakafi™ QL Nexavar® QL Sprycel® QL Sutent® QL Tarceva® QL Tykerb® CC, QL Xalkori® QL Xeloda® CC, QL Zelboraf™ CC, QL Zytiga™ CC – Clinical Criteria Relative Cost $$ $$ $$ $$ $$ $$ $$ $$ $$ $$ $$ $$ $$ $$ $$ Non-Preferred Agents QL Afinitor™ QL Tasigna® QL Votrient™ MD – Medications with Maximum Duration Relative Cost of Most Agents $$ QL – Quantity Limit ST – Step Therapy Page 32 of 32