Name ___________________________________________________________ Period ___________ Date _______________________ Lab: Online Karyotyping Activity From The Biology Project, University of Arizona (Warren, D. K. (1996). Web Karyotyping Activity. The Biology Project [Online], Available: http://www.biology.arizona.edu/human_bio/) Directions: Go to the website below: http://www.biology.arizona.edu/human_bio/activities/karyotyping/karyotyping.html Or search: Karyotyping Activity The Biology Project and select the first link to bring up the activity. Follow the online directions to determine the karyotype of three individuals with different genetic abnormalities. Answer the questions embedded in the activity on this paper as you go. Once finished, follow the directions to complete internet research and report your findings. Patient A: Patient A is the nearly full-­‐term fetus of a forty year old female. Chromosomes were obtained from fetal epithelial cells acquired through amniocentesis. Complete Patient A's Karyotype. A 1. What notation would you use to characterize Patient A’s karyotype? A 2. What diagnosis would you give patient A? A 3. What types of symptoms could Patient A expect based on your diagnosis? Do some research on other websites if necessary. Patient B: Patient B is a 28 year old male who is trying to identify a cause for his infertility. Chromosomes were obtained from nucleated cells in the patient's blood. Complete Patient B's Karyotype. B 1. What notation would you use to characterize Patient B’s karyotype? B 2. What diagnosis would you give patient B? B 3. What types of symptoms could Patient B expect based on your diagnosis? Do some research on other websites if necessary. Patient C: Patient C died shortly after birth, with a multitude of anomalies, including polydactyly and a cleft lip. Chromosomes were obtained from a tissue sample. Complete Patient C's Karyotype. C 1. What notation would you use to characterize Patient C’s karyotype? C2. What diagnosis would you give patient C? C 3. What types of symptoms could Patient C expect based on your diagnosis? Do some research on other websites if necessary. Final thoughts: Give two reasons why a pregnant woman would want a karyotype of her unborn baby. Give two reasons why a pregnant woman would NOT want a karyotype of her unborn baby.