Remediation Template: Medication Content Drugs for Neurological Disorders: Parkinsonism and Alzheimer's Disease Topic Descriptor Anticholinergics Review Module Chapter 23 Medication biperiden HCI (Akineton) Expected Pharmacological Action Blocks acetylcholine's action at cholinergic receptor sites. This action restores the brains normal dopamine and acetylcholine balance, which relaxes muscle movement and decreases rigidity and tremors. Biperiden amy also inhibit dopamine reuptake and storage, which prolongs dopamine's action. Therapeutic Uses All types of parkinsonism Side / Adverse Effects Dry mouth, blurred vision, drowsiness, muscle weakness, and constipation. Medication / Food Interactions None mentioned. Note: Information obtained from text. Nursing Interventions / Client Education Nursing Interventions / Client Education Monitor vital signs, urine output, and bowel Encourage patient to ingest foods high in fiber sounds. Caution patient to avoid driving and and increase fluid intake to avoid constipation. other activities until biperiden's CNS affects are Client may use hard candy for dry mouth. known. Emphasize the need for periodic eye examinations and intraocular pressure Note: Information obtained from text. measurement because biperiden may cause Nursing Administration narrow angle glaucoma and increase intraocular pressure. use diseaseAs an adjunct to treatSuggest all formsthe of client Parkinson's sunglasses in direct because Tablets: Adult 2 mg sunlight t.i.d. or q.i.d. up toof16 mg daily. photophobia. To control extrapyramiddal symptoms (except tardive dyskinesia) caused by phenoththiazines and other Note: Information neuroleptic drugs-obtained from 2012 Nurse's Drug Handbook Tablets: Adults 2and mgText. one to three times a daily. I.V. or I.M. 2 mg repeated every 30 min. until symptoms resolve or maximum of four consecutive doses in 24 hour is reached. Evaluation of Medication Effectiveness Assess muscle rigidity and tremor as baseline. Then check improvement, indicating biperiden's Note: Information obtained from 2012 Nurse's Drug Handbook effectiveness. Note: Information obtained from 2012 Nurse's Drug Handbook www.atitesting.com © 2010 Assessment Technologies Institute®, LLC