Ninth Grade Biology Unit 3 – Growth and Heredity Asexual and Sexual Reproduction: (SB2e) o o o o What is the role of DNA in storing and transmitting cellular information? How are genes, chromosomes and DNA related? What are the advantages of sexual reproduction and asexual reproduction in different environmental situations? How do sexual and asexual reproduction in organisms compare? Vocabulary: Genes Chromosomes Haploid nitrogenous bases (A,T,C,G) DNA RNA Diploid Binary Fission Sexual Reproduction Asexual Reproduction Conjugation Zygote Regeneration Differentiated Instructional Strategies: (References: Science Formative Assessment by Page Keeley; Differentiated Instructional Strategies by Gayle Gregory and Carolyn Chapman) o o o o Questionnaire- Students are given a short questionnaire to determine their prior knowledge of mitosis and meiosis, genes, and chromosomes(pre-assessment) Fun Bugs Activity- Illustrates mitosis, meiosis, sexual and asexual reproduction. ( Students must have prior knowledge of genes and chromosomes)(Comprehension) Group discussion panel on the advantages of sexual and asexual reproduction in various organisms in various environmental situations.(Evaluation)(Gifted) English Language Learners (ELL): Make a compare/contrast chart of organisms based on sexual or asexual reproduction. Suggested Laboratory Activities: (Reference: Biology, Glencoe) o Comparing Sexual and Asexual Reproduction o Reproduction lab- Protists and Fungi Internet Resources: o Asexual Reproduction o Detailed discussion of asexual reproduction in plants and animals o Venn Diagram on Asexual vs. Sexual Reproduction Blue indicates hyperlink to Internet Site Ninth Grade Biology Unit 3 – Growth and Heredity Cell Growth: (SB1a;SB2b) o o o o o What is the role of cell organelles in cell reproduction? Why is regulation of the cell cycle important? What causes uncontrolled cell growth? What is the difference between embryonic stem cells and adult stem cells? What is programmed cell death? Vocabulary: Cell cycle Mitosis Meiosis cyclins centriole spindle fiber chromosomes cell differentiation embryonic stem cell adult stem cell malignant tumor apoptosis crossing over Differentiated Instructional Strategies: (References: Science Formative Assessment by Page Keeley; Differentiated Instructional Strategies by Gayle Gregory and Carolyn Chapman) o o o o o Think-Pair-Share: Have students work with a partner and share prior knowledge of mitosis and meiosis(pre-assessment) Have students make flip books of mitosis and meiosis using yarn to represent the chromosomes.(Comprehension) Debate the use of adult versus embryonic stem cells for research (Debate Protocol) Prepare a presentation on current stem cell research.(Evaluation)(Gifted) English Language Learners (ELL): Make a foldable comparing mitosis and meiosis. (See Glencoe Resources) Suggested Laboratory Activities: (Reference: Biology, Glencoe) o Online Onion Root Tip Lab o Meiosis Lab Internet Resources: o Mitosis and Meiosis Activities o Meiosis Square Dance Video (free trial available- this video is worth it) o Apoptosis Blue indicates hyperlink to Internet Site Ninth Grade Biology Unit 3 – Growth and Heredity Mendelian Genetics: (SB2c) o o o Using Mendel’s laws, what is the role of meiosis in reproductive variability? How can genetic variations be hidden in one generation and expressed in the next? What are some patterns of gene expression? phenotype test cross Punnett Square Vocabulary: genotype probability karyotype Allele codominance trait homozygous Gene incomplete dominance homologous heterozygous Dominant Recessive hybrid Law of Dominance Law of Independent Assortment Law of Segregation Differentiated Instructional Strategies: (References: Science Formative Assessment by Page Keeley; Differentiated Instructional Strategies by Gayle Gregory and Carolyn Chapman) o o o o “Sticky Bars”- Teacher puts multiple choice questions on the board one at a time using Powerpoint or electronic whiteboard. Students write their answers anonymously on sticky notes and the teacher collects them and places them on the board to show the responses in a bar graph format. (Electronic voting may also be used) (pre-assessment) Read and discuss the article on the Blue People of Kentucky as a springboard for discussion on inheritance of traits. Have students write for two minutes on what they have learned from the article (formative assessment) List some common assumptions (misconceptions) about genetic inheritance. Give the scientific basis for your corrections.(Evaluation)(Gifted) English Language Learners (ELL): View a list of dominant and recessive traits and research which of your friends or members of your family have the same traits. Have students complete the "Handy Family Tree" activity (Spanish instructions included). Suggested Laboratory Activities: (Reference: Biology, Glencoe and Internet Resources) o Dragon Genetics Lab o Dominant and recessive traits lab o Solving Genetics Problems o Human genetics webquest o Karyotype and genetic traits lab o Pedigree Lab Internet Resources: o Punnett Squares o Mendelian Genetics Resource o Handout on dominant and recessive traits Blue indicates hyperlink to Internet Site Ninth Grade Biology Unit 3 – Growth and Heredity DNA and RNA Processes: (SB2a,b) o o o What are the differences between DNA and RNA? What is the role of DNA in the storing and transmitting of genetic information? What is the role of RNA in the transcription and translation of genetic information? transcription genes Vocabulary: translation tRNA DNA codon mRNA RNA anticodon rRNA Replication cDNA mtDNA Differentiated Instructional Strategies: (References: Science Formative Assessment by Page Keeley; Differentiated Instructional Strategies by Gayle Gregory and Carolyn Chapman) o o o o o o “No-Hands Questioning”- Teacher poses a question, practices wait time, and then calls on students to answer the question. Prepare questions ahead of time, including probe questions to extend student thinking. Make sure to practice the proper wait time for students to answer(pre-assessment) Class Activity: Making Codon Messages(DNA's Secret Message) Game: Codon Bingo Gifted Extension: Students prepare an annotated bibliography of current research on DNA and RNA (Evaluation) English Language Learners (ELL): Students make models of DNA using craft resources or make candy models of DNA. Build Your DNA and Eat It Too Suggested Laboratory Activities: (Reference: Biology, Glencoe and Internet Resources) o Building Origami DNA Models o Modeling DNA Replication o transcription and translation of DNA Internet Resources: o John Kyrk's Cell Biology Animation(Excellent) o DNA Replication Animation o mitochondrial DNA Blue indicates hyperlink to Internet Site o Animation of Transcription and Translation o Activities for Biotechnology o DNA Replication (Includes Quick Time Video animation) Ninth Grade Biology Unit 3 – Growth and Heredity Chromosomes and Mutations and Biological Resistance: (SB2d;SB4d;SB5e) o o o o How do mutations affect evolution? What are genetic diseases that are caused by mutations? What are the different types of mutations that can occur in organisms? What is the relationship of evolution to biological resistance? (pesticide and antibiotic resistance) Vocabulary: Single gene mutations Polygenic mutations Chromosomal mutations Mitochondrial DNA mutations nondisjunction insertion substitution deletion chromosomal translocation mutagenic factors (radiation, chemical) biological resistance point mutation Differentiated Instructional Strategies: (References: Science Formative Assessment by Page Keeley; Differentiated Instructional Strategies by Gayle Gregory and Carolyn Chapman) o o o o Working in groups, students write down the name of all the diseases that they believe are genetically related. The students will write their responses on a small piece of whiteboard or poster board. The teacher will call on each group to share their responses and discuss. As the discussion progresses, students may add or remove items from their list.(pre-assessment) Make an informational brochure for the public about a particular genetic disease.(Application) Gifted Extension: “What is the impact of overuse of antibiotics on biological resistance?”(Evaluation) English Language Learners (ELL): Have students choose a genetic disease to research and present a Powerpoint presentation. Suggested Laboratory Activities: (Reference: Biology, Glencoe and Internet Resources) o "Does Sunscreen Protect My DNA?"(Practical application Lab) o Mystery Yeast Mutation Lab o Gene Therapy Webquest Internet Resources: o Genetic Disorders o Development of Biological Resistance Blue indicates hyperlink to Internet Site Ninth Grade Biology Unit 3 – Growth and Heredity Genetic Engineering and Bioethics: (SB2f) o o o o How has genetic engineering influenced food and medicine? How is cloning currently used in food and medicine? How is stem cell research being used to benefit humans? What are the bioethics issues surrounding stem cell research and cloning? Vocabulary: Cloning Transgenic animals Stem Cells Bioethics Biological Resistance Differentiated Instructional Strategies: (References: Science Formative Assessment by Page Keeley; Differentiated Instructional Strategies by Gayle Gregory and Carolyn Chapman) o Questionnaire: Give students a short questionnaire to see what they know about genetic engineering (cloning, stem cells). Use this questionnaire as a guide to instruction on these topics. (pre-assessment) What Do You Know About Stem Cells? (Pre-assessment Activity) o Construct a timeline of cloning using the activity "You've Come a Long Way Dolly"(Analysis) o o o o o Students work in groups to explore the Bioethics of Human Cloning(Evaluation) (Comprehension) Have students make a hypothesis about biological resistance and the overuse of antibiotics (Analysis) Conduct a debate about stem cell research or cloning.(Synthesis)(Gifted) English Language Learners (ELL): Make a flow chart to show the cloning process or to illustrate how stem cells are used. Suggested Laboratory Activities: (Reference: Biology, Glencoe and Internet Resources) o Cloning In Focus Webquest o Bioethics of Gene Therapy o Embryos-R-Us Case Study (Bioethics) o Meeting In Mutantville Case Study (Bioethics) Internet Resources: o Build a Gel Electrophoresis Chamber Blue indicates hyperlink to Internet Site Ninth Grade Biology Unit 3 – Growth and Heredity DNA Technology (SB2f) o How is DNA fingerprinting used to identify a person? o What is the use of polymerase chain reactions (PCR)? o How is bacterial transformation used in medicine? o How is gel electrophoresis used in DNA technology? Vocabulary: Polymerase Chain Reaction Gel Electrophoresis Bacterial Transformation DNA Fingerprinting Southern Blotting Technique Differentiated Instructional Strategies: (References: Science Formative Assessment by Page Keeley; Differentiated Instructional Strategies by Gayle Gregory and Carolyn Chapman) o o o o “No-Hands Questioning”- Teacher poses a question, practices wait time, and then calls on students to answer the question. Prepare questions ahead of time, including probe questions to extend student thinking. Make sure to practice the proper wait time for students to answer(pre-assessment) Class Activity: Forensics Lab Activity Gifted Extension: Students design a webquest on DNA technology(Evaluation) English Language Learners (ELL): Students solve a crime by using DNA fingerprinting evidence: Forensics Lab Activity Suggested Laboratory Activities: (Reference: Biology, Glencoe and Internet Resources) o Simulated Gel Electrophoresis Lab o History of DNA Webquest (includes Griffith’s Transformation Experiment) Internet Sites: o Genetics Lesson Plan Ideas o Build a Gel Electrophoresis Chamber o Solving Crimes Using DNA Evidence Blue indicates hyperlink to Internet Site