BI217 – Human Physiology II January 2015
B217- Human Physiology II: Structure, Function & Integration
Course Instructor: Dr. Michael Wilkie, Science N3021H, ext. 3313, Email: via MyLS
Office Hours: Tuesday 1430-1630, N3021H
Lab Coordinator: Dr. Tom Singer, Science N3031, ext. 3397, Email: tsinger@wlu.ca
Lectures: T, R – 1130-1250, BA208. Laboratories: Wednesday, N3032
Required Course Materials:
(1)
(2)
Principles of Human Physiology – 5 th
Edition by C. L. Stanfield
Web Access to PhysioEx 9.0 for Human Physiology by Zao et al.
(3)
(4)
InterActive Physiology - a CD-ROM version is included with the text (limited term online software access is also included with the purchase of a new text)
Access to MyLearningSpace (MyLS)
The goal of this course is to delve further into the concept of homeostasis, which is defined as the ability of the body to maintain a relatively constant internal environment. Particular emphasis will be placed on the roles that the nervous and endocrine systems play in the control of human physiological processes at the genetic, cellular, tissue, organ and whole body levels of organization. Beginning with a review of cell structure and function, a mechanistic approach will be used to illustrate how processes mediated by cell membranes are essential for regulating physiological systems in the body. This will be followed by a discussion of how the nervous system functions to rapidly coordinate the body’s voluntary and involuntary activities, with an emphasis on the cardiovascular, renal, respiratory and reproductive control systems. The role of the endocrine system in the longer-term control of physiological processes will be explored by discussing how the pituitary gland and hypothalamus, thyroid hormones, and insulin and glucagon regulate growth, development, metabolism, and other functions. The course will conclude by addressing the essential roles that hormones play in regulating male and female reproductive physiology.
The purpose of laboratory sessions is to provide students with an opportunity to perform physiological experiments and observe demonstrations that have been designed to complement, enhance understanding of, and expand upon the lecture material. Laboratory exercises involve a problem-based approach and collaborative learning. Each laboratory exercise lists related readings from both the course text and the
Interactive Physiology CD ROM/website. Many laboratory exercises will incorporate PhysioEx
TM computer simulations. In some instances, the computer simulations are based on experiments that until recently could only be completed using live animal preparations. Online access to PhysioEx 9.0
 is included with purchase of a new course text. Some lab exercises will also involve recording physiological data from volunteer human subjects with a PowerLab system. Students are also expected to check MyLS prior to the first lab period of each week for any lab manual updates and following the completion of the last lab period of the week for typical results and additional information related to the current week’s lab exercises.
Two problem-based tutorial sets will be assigned to further your understanding of human physiology in health and disease. You will have 1-2 weeks to complete these problem sets, which will be taken up and discussed in tutorial sessions scheduled during your laboratory period. Problems will be similar to those that will appear on your mid-term and the final exam. You are strongly encouraged to complete ALL
QUESTIONS on these assignments, and to raise any questions that you have in the tutorial sessions before the mid-term and the final exam, or via discussion groups on MyLS. You will also write a short (2 page) pathophysiology paper describing the underlying mechanisms and treatments of a specific disease that affects one of the above physiological systems. Possible topics will be posted on MyLS, and you will indicate your choice of disease on a sign-up sheet during your laboratory. Late papers will be penalized at a rate of minus 10 % per day.
You are also responsible for all of the material in chapter readings that is assigned to you. To pass this course, ALL components must be completed satisfactorily.
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BI217 – Human Physiology II January 2015
GRADING*
(1) Mid-term - 15 % (Thursday, February 12, 1130-1250)
(2) Pathophysiology Paper - 15 % (Research Summary Due on Tuesday, February 24; Final
Paper Due on Thursday, March 26, 11:30 AM)
(3) Laboratories - 35 %
- Weekly quizzes (15%), Weekly Assignments (10 %), Two Problem Sets (10 %)
(4) Final Exam (cumulative) – 35 %
* This proposed grading scheme may change at the discretion of the course instructor.
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BI217 – Human Physiology II January 2015
Lecture TOPIC
Part I – Review of the Concept of Physiology & Homeostasis
Independent Cell structure, functional organization of the body
Study (Review material for which you are responsible)
Part II – Membrane Physiology
1 Introduction to Human Physiology
2, 3
4, 5
Cell membrane transport
Chemical Messengers
Part III – The Nervous System
6 Nerve Cells & Electrical Signaling
7 Autonomic Nervous System (ANS) and the Adrenal Medulla
Part IV - Cardiovascular Control
8, 9 Cardiovascular System I The Human Heart: Nature’s Perpetual Pump
10 Cardiovascular System II - Blood, Blood Flow, & Blood Pressure
11 Cardiovascular System III – Regulation, Shock and Exercise
Mid-term – Thursday, February 12, 1130-1250 (Lectures 1-11)
Part V – Respiration
12 Respiratory System I - Breathing Mechanics
13 Respiratory System II - Gas Exchange & the Regulation of Breathing
Part VI – The Excretory System - Fluid, Electrolyte and Acid-Base Balance
14 Overview of Kidney Function & the Body Fluids
15, 16 Control of Electrolyte, Osmotic, & Acid-Base Balance
20
21
22
Part VII – The Endocrine System & Reproduction
17 Introduction to Endocrinology
18
19
Pituitary Hormones & the Hypothalamus
Thyroid hormones, Insulin & Glucagon
Reproduction & Hormones in Males
Female Reproductive Endocrinology Before Pregnancy
Pregnancy, Child-birth & Lactation
Part VIII – Integrative Physiology
23 Life in Extreme Environments: Human Survival & Adaptation
Chapter
1, 2
22
22
22
6
21
21
1
4
5
7
11
13
14, 15
14
16
17
18
17, 19
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BI217 – Human Physiology II January 2015
Adding and Dropping
Important Dates for Course Adding/Dropping and Tuition charges for the Fall 2014 Term, please see this link: http://www.wlu.ca/calendars/dates.php?cal=1&t=210&y=61
Important Dates for Course Adding/Dropping and Tuition charges for the Winter 2015 Term, please see this link: http://www.wlu.ca/calendars/dates.php?cal=1&t=211&y=61
Examination Deferrals
The Academic Date section of the Calendar (Printed and Web Site Versions) clearly states the examination date period for each semester.
Students must note that they are required to reserve this time in their personal calendars for the examinations. The Fall examination period is:
December 6-19, 2014 . The Winter examination period is: April 9-28, 2015.
Students who are considering registering to write MCAT, LSAT or
GMAT or a similar examination, should select a time for those examinations that occurs outside the University examination period. For additional information that describes the special circumstances for examination deferment, please check the following web page: http://www.wlu.ca/page.php?grp_id=1&p=17294 – Faculty of Science: Request for Deferred Final Examination.
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