DKA CASE STUDY Sam, a 39-year-old, 63 kg (140 lb) African-American man, was admitted to the hospital with diabetic ketoacidosis (DKA). After admission to the emergency room, he had multiple episodes of emesis. Sam said he had been vomiting for the past 2 days and admitted to skipping several doses of insulin recently. He mentioned that he had feverish feelings at home and reported an occasional cough. Sam’s assessment revealed the following: pain throughout all abdominal quadrants with “cramping” reported in all four abdominal quadrants. He was extremely lethargic and difficult to arouse at times. He complained of severe thirst. His skin was extremely dry. Electrocardiogram (ECG) showed a sinus tachycardia at 120 bpm. Lungs were clear bilaterally, but respirations were deep and rapid. There was an acetone smell to Sam’s breath. He denied alcohol and illicit drug use and could recall no drug or food allergies. He did report that his father and two aunts have insulin-dependent diabetes. Sam’s psychosocial history revealed the following pertinent information. He works parttime as a janitor and intends to start a second job but only for 2 ½ hours a week. He stated, “I’m on a fixed income, and my medicine runs out sometimes.” During the past year, Sam has been admitted to the hospital with the diagnosis of DKA on March 2 nd, June 29th, and November 8th. In addition, he had failed to keep his follow up appointments on July 18 th and November 23rd. Sam’s diagnostic data are: BP HR Respirations Temperature 12480 122 bpm 32 / min 35.8 degrees C (96.3 degrees F) (Oral) Hematologic Studies Hgb Hct Cholesterol Ca++ Phosphorus Na+ K+ LDH Alkaline phosphatase ClCreatinine BUN Glucose Acetone AST (SGOT) CK 14.5 g/dl 58% 338 mg/dl 8.8 mmol/L 6.8 mg/dl 126 mmol/L 5.3 mmol/L 38 U/L 132 U/L 95 mmol/L 4.9 mg/dl 52 mg/dl 560 mg/dl moderate 248 U/L 34/35 IU/L Arterial Blood Gases pH 7.19 Po2 100 mm Hg HCO3 7.5 mmo/L Pco2 20 mm Hg Sao2 98% (room air) Urine Specific gravity 1.015 Ketones 4+ Leukocytes few Glucose 4+ Nitrates 0 RBCs many Home Medications AM 16 U 70/30 insulin PM 12 U 7030 insulin 1. What is insulin’s function in the body? What is the most significant basic defect in the development of DKA ? Describe the interplay of factors necessary for the development of DKA. 2. List the classic signs and symptoms of DKA. 3. Sam’s pH of 7.19 indicates severe acidosis. Discuss Sam’s arterial blood gases (ABGs) in regard to acid-base balance. 4. Discuss the possibility of an infection in Sam’s case and the effect sepsis or infection would have on a diabetic patient. 5. What are the goals of treatment for DKA? 6. Identify Sam’s abnormal laboratory values and describe the treatment modalities used with a patient with DKA in regard to these values. 7. What are four major complications associated with DKA and its treatment? 8. Review Sam’s history and laboratory values to determine the diabetic complications to which Brady is most predisposed. 9. What nursing considerations are important in planning Sam’s discharge?