Animal Tissues and Organ Systems Chapter 32 Impacts, Issues Open or Close the Stem Cell Factories? Only embryonic stem cells can differentiate into any specialized cell in the body; engineered stem cells are not yet safe for humans Homeostasis in Animals Body parts must interact to perform many tasks • Coordinate and control individual parts • Acquire and distribute raw materials to cells and dispose of wastes • Protect tissues against injury or attack • Reproduce, nourish and protect offspring through early growth and development • Maintain the internal environment (homeostasis) 32.1 Organization of Animal Bodies Tissue • Interacting cells and extracellular substances that carry out one or more specialized tasks Organ • Structural unit of two or more tissues organized in a specific way to carry out specific tasks Organ systems • Two or more organs and other components interacting in a common task Animal Cells are United by Cell Junctions Tight junctions • Prevent fluid from seeping between epithelial cells; fluid must pass through cells Adhering junctions • Hold cells together at distinct spots Gap junctions • Permit ions and small molecules to pass from cytoplasm of one cell to another 32.1 Key Concepts Animal Organization All animals are multicelled, with cells joined by cell junctions Typically, cells are organized in four tissue types: epithelial tissue, connective tissue, muscle tissue, and nervous tissue Organs, which consist of a combination of tissues, interact in organ systems 32.2 Epithelial Tissue Epithelium (epithelial tissue) • A sheet of cells that covers the body’s outer surface and lines its internal ducts and cavities Basement membrane • A secreted extracellular matrix that attaches the epithelium to the underlying tissue Microvilli • Fingerlike projections of absorptive epithelia General Structure of Simple Epithelium free surface of a simple epithelium basement membrane (material secreted by epithelial cells) underlying connective tissue Fig. 32-3, p. 541 Describing Epithelial Tissues Thickness • Simple epithelium: One cell thick • Stratified epithelium: More than one cell thick Cell shape • Squamous: Flattened • Cuboidal: Cube-shaped • Columnar: Tall Types of Epithelial Tissues Simple squamous epithelium • Lines blood vessels, the heart, and air sacs of lungs • Allows substances to cross by diffusion Fig. 32-4a, p. 541 Fig. 32-4b, p. 541 Simple cuboidal epithelium • Lines kidney tubules, ducts of some glands, oviducts • Functions in absorption an secretion, movement of materials Fig. 32-4b, p. 541 Fig. 32-4c, p. 541 Simple columnar epithelium mucus-secreting gland cell • Lines some airways, parts of the gut • Functions in absorption and secretion, protection Fig. 32-4c, p. 541 Glandular Epithelium Glands • Organs that release substances onto the skin, or into a body cavity or interstitial fluid Exocrine glands (glands with ducts) • Deliver secretions to an external or internal surface (saliva, milk, earwax, digestive enzymes) Endocrine glands (no ducts) • Secrete hormones which are carried in blood 32.3 Connective Tissues Connective tissues consist of cells and the extracellular matrix they secrete Connective tissues connect body parts and provide structural and functional support to other body tissues Soft Connective Tissues Loose connective tissue • Fibroblasts secrete a matrix of complex carbohydrates with fibers dispersed widely through the matrix Dense connective tissue (dense collagen fibers) • Dense irregular: Supports skin, internal organs • Dense regular: Ligaments and tendons Specialized Connective Tissues Cartilage: Rubbery extracellular matrix, supports and cushions bones Adipose tissue: Fat filled cells, stores energy, cushions and protect organs Bone: Rigid support, muscle attachment, protection, mineral storage, blood production Connective Tissues Connective Tissues Fig. 32-5a, p. 542 Fig. 32-5b, p. 542 Fig. 32-5c, p. 542 Fig. 32-5d, p. 542 Fig. 32-5e, p. 543 Fig. 32-5f, p. 543 Cartilage and Bone Tissue cartilage at the end of long bone compact bone tissue spongy bone tissue Fig. 32-6, p. 543 A Fluid Connective Tissue Blood: Plasma, blood cells and platelets white blood cell red blood cell platelet Fig. 32-7, p. 543 32.4 Muscle Tissues Muscle tissue is made up of cells that contract when stimulated, requires ATP energy Three Types of Muscle Tissues Skeletal muscle tissue • Moves the skeleton (voluntary) • Long, striated cells with many nuclei Cardiac muscle tissue • Heart muscle (involuntary) • Striated cells with single nuclei Smooth muscle tissue • In walls of hollow organs (involuntary) • No striations, single nuclei 32.5 Nervous Tissue Nervous tissue • Consists of specialized signaling cells (neurons) and cells that support them (neuroglial cells) Nervous tissue detects internal and external stimuli, and coordinates responses to stimuli Neurons Neurons • Excitable cells with long cytoplasmic extensions • Send and receive electrochemical signals Three types of neurons • Sensory neurons are excited by specific stimuli • Interneurons integrate sensory information • Motor neurons relay commands from brain and spinal cord to muscles and glands A Motor Neuron Coordination of Nervous Tissue and Skeletal Muscle 32.2-32.5 Key Concepts Types of Animal Tissues Epithelial tissue covers the body’s surface and lines its internal tubes Connective tissue provides support and connects body parts Muscle tissue moves the body and its parts Nervous tissue detects internal and external stimuli and coordinates responses 32.6 Overview of Major Organ Systems In vertebrates, organs arise from three embryonic germ layers • Ectoderm (outermost layer) forms nervous tissue and epithelium of skin • Mesoderm (middle layer) forms muscle, connective tissue, and lining of body cavities • Endoderm (innermost layer) forms epithelium of gut and lungs Body Cavities and Directional Terms Body Cavities and Directional Terms Body Cavities and Directional Terms cranial cavity spinal cavity thoracic cavity diaphragm abdominal cavity pelvic cavity Fig. 32-11a, p. 546 Dorsal Surface transverse midsagittal ANTERIOR POSTERIOR frontal Ventral Surface Fig. 32-11b, p. 546 SUPERIOR (of two body parts, the one closer to head) frontal plane (aqua) midsagittal plane (green) ANTERIOR (at or near front of body) distal (farthest from trunk or from origin of a body part) proximal (closest to trunk or to point of origin of a body part) POSTERIOR (at or near back of body) INFERIOR (of two body parts, the one farthest from head) transverse plane (yellow) Fig. 32-11c, p. 546 Animation: Human body cavities Animation: Directional terms and planes of symmetry Eleven Vertebrate Organ Systems Eleven Vertebrate Organ Systems Integumentary System Protects body from injury, dehydration, and some pathogens; controls its temperature; excretes certain wastes; receives some external stimuli. Nervous System Detects external and internal stimuli; controls and coordinates responses to stimuli; integrates all organ system activities. Muscular System Moves body and its internal parts; maintains posture; generates heat by increases in metabolic activity. Skeletal System Supports and protects body parts; provides muscle attachment sites; produces red blood cells; stores calcium, phosphorus. Circulatory System Rapidly transports many materials to and from interstitial fluid and cells; helps stabilize internal pH and temperature. Endocrine System Hormonally controls body functioning; with nervous system integrates shortand long-term activities. (Male testes added.) Fig. 32-12a, p. 547 Lymphatic System Respiratory System Digestive System Collects and returns some tissue fluid to the bloodstream; defends the body against infection and tissue damage. Rapidly delivers oxygen to the tissue fluid that bathes all living cells; removes carbon dioxide wastes of cells; helps regulate pH. Ingests food and water; mechanically, chemically breaks down food and absorbs small molecules into internal environment; eliminates food residues. Urinary System Maintains the volume and composition of internal environment; excretes excess fluid and bloodborne wastes. Reproductive System Female: Produces eggs; after fertilization, affords a protected, nutritive environment for the development of new individuals. Male: Produces and transfers sperm to the female. Hormones of both systems also influence other organ systems. Fig. 32-12b, p. 547 Animation: Human organ systems 32.6 Key Concepts Organ Systems Vertebrate organ systems compartmentalize the tasks of survival and reproduction for the body as a whole Different systems arise from ectoderm, mesoderm, and endoderm, the primary tissue layers that form in the early embryo 32.7 Vertebrate Skin— Example of an Organ System Skin is the body’s interface with the environment • Sensory receptors, barrier against pathogens, internal temperature control, water conservation Vertebrate skin is made up of all four tissue types arranged in two layers: • Outer epidermis contain keratinocytes • Deeper dermis contains nerves, blood and lymph vessels, hair follicles and glands Skin Structure Skin Structure Skin Structure hair epidermis dermis hypodermis oil gland hair follicle blood vessels sensory neuron sweat gland smooth muscle Fig. 32-13a, p. 548 outer flattened epidermal cells cells being flattened dividing cells dermis Fig. 32-13b, p. 548 hair’s cuticle one hair cell keratin macrofibril keratin polypeptide chain Fig. 32-13c, p. 548 Animation: Structure of human skin Animation: Hair fine structure Frog Skin Amphibians may have glands that secrete mucus, distasteful chemicals, or poisons • Pigmented cells in dermis warn predators Fig. 32-14b, p. 549 mucous gland poison gland pigmented cell Fig. 32-14b, p. 549 Sunlight and Human Skin Melanocytes in skin make a brown pigment (melanin) which affects skin color and tanning Melanin protects against UV radiation • A little UV promotes vitamin D production • A lot of UV damages DNA and promotes cancer 32.8 Farming Skin Commercially grown skin substitutes are already in use for treatment of chronic wounds Skin may be a source of stem cells that could be used to grow other organs 32.7-32.8 Key Concepts A Closer Look at Skin Skin is an example of an organ system It includes epithelial layers, connective tissue, adipose tissue, glands, blood vessels, and sensory receptors It helps protect the body, conserve water, control temperature, excrete wastes, and detect external stimuli Animation: Altering hair structure Animation: Cell junctions Animation: Functional zones of a motor neuron Animation: Muscle tissues Animation: Organization of animal cells Animation: Soft connective tissues Animation: Specialized connective tissues Animation: Structure of an epithelium Animation: Types of simple epithelium ABC video: A Saving Graft ABC video: New Hands Video: Stem Cells