USC CHEMIST
A Newsletter for Alumni and Friends of the Department
Department of Chemistry and Biochemistry College of Arts and Sciences University of South Carolina
Fall 2005
Creating the New College
By Dean Mary Anne Fitzpatrick
T
his semester we
have been celebrating the reformation of the College
of Arts and Sciences at the
University of South Carolina. We have marked this
occasion with public ceremonies, convocations, and Mary Anne Fitzpatrick
lectures. Through these celebrations, the members of our
community have recommitted to the principles
and values that guide us in our work. Rituals
like this serve to remind us that the faculty and
the staff across the college have the same goals:
to educate students, to create new knowledge,
and to transfer information to the public. Many
traditional small liberal arts colleges can educate
students, and many well-funded research institutes can create new knowledge, but it is only
a College of Arts and Sciences that takes on all
three of these goals as core to its mission.
Two hundred years after USC officially
opened its doors in January of 1805, the University of South Carolina opened the newly con-
solidated College of Arts and Sciences. Keeping
our traditional core of the study of the classics,
rhetoric, and mathematics, we have grown as a
consequence of innovation and responsiveness
to the intellectual and cultural world around us.
The scope of the college and the disciplines it
represents is a broad one, but the overriding
ambition of everyone in the college is to build
a great teaching and research institution by
attracting leading scholars and students from
around the country and the world. Driving this
success is our faculty. Because of their achievements, the college attracts outstanding graduate
and undergraduate students. Excellent senior
faculty recruit outstanding young faculty and
students.
The Department of Chemistry and Biochemistry is a cornerstone of the new College of Arts
and Sciences. With 27 faculty, the department
boasts world-class research programs in analytical, biochemistry, inorganic, organic, and physical chemistry, housed in a 158,000-square-foot
research building. As regular readers of the
newsletter know, the faculty in chemistry and
biochemistry continue to have their achieve-
ments recognized with major national and international honors. Based on numbers of doctorates awarded, the American Chemical Society
consistently lists the department as one of the
top 40 programs in the country. The department
is strong because it focuses on undergraduate
education as well. Last year, the department
generated 5.6 percent of all the undergraduate
credits in the college, demonstrating that students respond when faculty are accessible even
as they challenge students to hone their scientific reasoning and problem-solving abilities.
The College of Arts and Sciences holds in
trust the mandate to deliver general education
for the entire University. Ninety percent of the
freshman and sophomore credit courses are
taught by our faculty and staff. College faculty
members need to teach students to understand
the importance of disciplines in which they
have decided not to become experts. One cannot overstate the importance of the department
in the undergraduate curriculum for all students
at the University of South Carolina. One of the
core jobs for the department is to exercise leadership and innovation in designing those first
College cont. on pg. 7
Brewer Leads Freshman Forensics Course at USC
The spring 2005 section of Chemistry 107 was an
experience that USC students outside of science have
never had before. Dr. Bill Brewer led an “introduction to
forensic science for non-science majors.” This course was
designed to introduce modern scientific investigation
techniques to freshman-level students and those from
other colleges at USC.
An Introduction to Forensic Science was a team effort.
It was taught not only by Dr. Brewer, but also by coinstructors Dr. Demi Garvin and Dr. Gray Amick, both
with the Richland County Sheriff’s Department (RCSD), and Dr. Scott
Goode and Dr. Steve Morgan, both from USC’s Department of Chemistry
and Biochemistry. Several guest lecturers who specialized in particular
forensic science disciplines were also brought in. “What made the course
really unique was that we brought in experts from every
field—actual practicing forensic scientists from SLED, the
Sheriff’s Department, and the private sector. That made it one
of a kind, because we could talk about true case studies,” said
Dr. Brewer about the course. The course also used a Web site
to post lecture slides, laboratory assignments, and important
announcements.
The students were presented with information on many
different areas of crime scene investigation, including footprints, fingerprints, toxicology, hair and fibers, tire marks,
DNA, anthropology, and others. During each lecture, the students were
instructed in the process of finding the evidence and processing it. They
were given firsthand scenarios of actual cases and key forensic evidence
that helped solve them.
Forensics cont. on pg. 3
From the Chair
The 2004–2005 academic year brought many exciting changes to the
Department of Chemistry and Biochemistry. The year started with the
return of Jerry Odom to the department after seven years of serving
as Provost of the University. Jerry is back doing what he likes best,
teaching introductory chemistry. I can tell you that there are a lot of
lucky students out there who are happy that he is back. It ended with
the retirement of Roy Wuthier, who has been an outstanding teacher,
researcher, and role model for us all. Although retired, Roy continues
to run a well-funded and very productive research program.
A major change in organization of the University took place over
the winter with the merger of the College of Science and Mathematics
with the College of Liberal Arts to form the new College of Arts and
Sciences. The new college is led by Dean Mary Anne Fitzpatrick, who
comes to us from the University of Wisconsin with a broad range of
administrative experience. The merger has been a major undertaking, and now eight months down the road, the new college is clearly
forming its own identity.
Amidst this change, the Department of Chemistry and Biochemistry has undergone aggressive growth with outstanding support
from the dean, the vice president for research, and the provost.
We have hired four new tenure track assistant professors. Dr. Ben
Twining is a chemical oceanographer who did his graduate work at
Stony Brook University and postdoctoral work at Yale. This hire is a
unique opportunity for the Department of Chemistry and Biochemistry and fits well with the plans being formulated by the University
Environmental Research Initiative Committee of hiring new faculty
that carry out environmental research. In addition to bringing new
research opportunities to the University of South Carolina, Ben will
also strengthen our developing undergraduate curriculum in environmental chemistry. Dr. Caryn Outten is a biochemist who received
her Ph.D. degree at Northwestern in chemistry and was an NIH postdoctoral fellow at Johns Hopkins. She will bring a funded National
Institute of Environmental Health Sciences Transition to Independent
Positions (NIEHS) “starter” grant to USC. Dr. Wayne Outten, also a
biochemist, received his Ph.D. degree at Northwestern in biochemistry and was a postdoctoral fellow at NIH. Both of their research
programs are in the University thrust area of biomedical research. Dr.
Linda Shimizu, an organic chemist, received her Ph.D. degree at MIT
in chemistry and was a NIH postdoctoral fellow in toxicology, also at
MIT. She was working as a research assistant professor at USC and
has been awarded two NSF grants.
In addition to these tenure track hires, Dr. Sheryl Wiskur has been
hired as a research assistant professor. Sheryl has her Ph.D. from
the University of Texas and two years of postdoctoral experience
at MIT. She has expertise in the syntheses of bioorganic molecules
USC CHEMIST
A Newsletter for Alumni and Friends of the Department
and will also work on the syntheses of
molecules that are important to our strong
collaborations with the NOAA laboratory in
Charleston. Finally, starting Oct. 1, Dr. Tom
Vogt will join the department as a tenured
full professor and as the new director of the
University of South Carolina NanoCenter.
Tom comes to us from the Brookhaven
National Lab in New York with outstanding
credentials as a leader in the crystallography Dr. Daniel Reger
community and with over 200 publications.
He replaces Professor Richard Adams, who was the first director of
the NanoCenter and did an outstanding job getting the center going.
Among his many achievements was bringing Dr. Richard Webb to the
University of South Carolina; Webb is a renowned physicist who is
in the National Academy of Sciences. Dr. Adams returns to full-time
teaching and continues to direct an outstanding research program.
We are very pleased that these hires have substantially increased
the number of women on our faculty. This year Dr. Donna Chen
became the second female on our faculty to be granted tenure and
was also promoted to associate professor.
We also have hired a new staff member, Rebecca Yates, to look
over our complicated graduate program and produce the nice document you are reading. The faculty I have been bragging on above
are supported by outstanding staff who keep this complicated operation running smoothly.
Our undergraduate enrollments have continued to climb as the
size of the University grows, and in an interesting development, a
higher percentage of the student body now takes our courses. Peer
and student evaluations make it clear that we are doing a good job
of teaching these students. Our graduate program is flourishing, with
strong funding of our research programs. Demonstrating our strong
performance in all areas, Dr. Cathy Murphy won the University
Russell Award for Research, and Jerry Odom received the Educational Foundation Outstanding Service Award. In addition, Richard
Adams won the Carolina Trustees Professor Award, presented yearly
to the University’s best professor who demonstrates excellence in
a combination of research, teaching, and service. A clear indication
of the strength of the Department of Chemistry and Biochemistry is
that this award has been given for seven years, and four times now a
member of our department has won the award.
The USC Chemist is written and edited by Rebecca Yates, with help on this issue from Dr. Stephen Morgan,
Dr. Stephen Kister, and Dr. Delana Nivens. To contribute alumni news or to submit feedback, go to our
Web page, www.chem.sc.edu/news/alumni/alumniinfo, or follow the links from the chemistry department
homepage, www.chem.sc.edu. You may also e-mail chemgradoffice@mail.chem.sc.edu or write to
USC Chemist, Department of Chemistry and Biochemistry, University of South Carolina, Columbia, SC 29208.
Dr. Steven Kistler: 30 Years of Looking at Novel
Chromosomal Proteins in Spermatogenic Cells
As everyone knows, it takes genetic information from the father and the
mother to get the next generation started on the road to development of a new
individual. Not so many people are aware that the chromosomes arriving from
the male have been repackaged several times to make the smallest possible
package for the sperm to carry to the ovum. The Kistler lab has been interested in this process ever since Dr. Steven Kistler was one of the first to identify
novel DNA packaging proteins in male germinal cells in the 1970s.
Dr. Kistler joined the chemistry faculty in fall 1975. A year later he
was married to Malathi Kistler, whom he met while both were postdocs
at the University of Chicago. Shortly thereafter, the funding of an initial
grant from the National Institute of Child Health and Human Development
(NIH) made possible the start of a scientific collaboration that continues
today. Aided by a series of talented students and postdocs over the years,
they have been intrigued by several aspects of sperm development and
the mechanism of male hormones like testosterone. “The goal is primarily
academic: Can we understand the program of changes in gene expression
that convert a typical-looking cell with a normal chromosome count into
a vastly altered sperm cell that carries half the usual chromosome complement? This must involve hundreds of genes turning on and off according to
a well-defined program. We would like to identify examples of these genes,
and more importantly, identify the controlling factors that turn them on and
off,” says Kistler of his research. There is a practical side to this research as
well. With enough detailed knowledge of the molecular basis of spermatogenesis, one might be able to design drugs that turn spermatogenesis off or
ones that might overcome blocks to spermatogenesis in certain individuals
with infertility. The ultimate aim would be to help provide pharmacological
tools to ensure that fertility for a particular couple would be neither more
nor less than wanted.
“In the 1980s we spent some time trying to understand how steroids
like testosterone activate particular genes in the male reproductive tract,
and this focus provided our first push into the relatively new area of recombinant DNA and gene cloning. In fact, Malathi created our first cDNA
clone (messenger RNA copied into DNA) just days before she gave birth
to our first child.” Building on this experience, they then went on to clone
genes for several DNA packaging proteins such as histone H1t and testis
nuclear protein 1. The first of these appears during meiosis in the testis,
and helps reorganize chromosome packaging early in spermatogenesis.
The second appears much later, when haploid cells are beginning the final
morphological changes that will make them into
mature sperm. Interestingly, while both these proteins are completely specific to spermatogenesis,
neither is retained in the mature sperm nucleus,
where yet a different group of proteins, known
as protamines, are the major DNA-packaging
components. For many years H1t was unique as
a completely tissue-specific histone in mammals.
Recently an H1 variant unique to oocytes was also
discovered, so that novel linker-histones accomDr. Steven Kistler
pany gamete development in both male and female.
Kistler adds, “most recently we have been trying to uncover the regulatory proteins that control expression of the H1t gene. Fortunately, NIH
has supported this work continuously since the 1970s, and our main grant
will be in its 26th year in August.” Over a decade ago, a gene regulatory
protein, designated RFX2, was identified as part of a protein family related
to a protein that helps regulate genes in the immune system. However, no
target was identified for RFX2. “Two years ago we realized that RFX2 is
probably identical to a DNA binding protein we had identified that interacts
with the control region (promoter) of the histone H1t gene. This may be
an important contribution since we have now identified functional binding
sites for RFX2 in the promoters of some half a dozen other genes that are
active during meiosis in the male.” This may indicate that RFX2 is one of
the master gene regulatory proteins of spermatogenesis and fits with the
fact that the protein is greatly enriched in spermatogenic cells. “We hope to
be able to identify additional RFX2 targets and also to move on to discover
the factors that cause RFX2 itself to be up-regulated during spermatogenesis,” said Dr. Kistler.
“It has been great fun participating in molecular biology over several
decades and progressing from protein chemistry to gene analysis and regulation. It has been a period of almost unimaginable scientific progress.”
When Dr. Kistler came to USC, the sequence was not known for any
human gene and very few had even been mapped to specific chromosomes.
Now virtually the entire human genetic code has been sequenced and is
available to anyone with Internet access at several Web sites, such as www.
genome.ucsc.edu. “It is truly remarkable that we are a species that has
learned to read our own set of master instructions, though we certainly do
not know how to interpret them all yet.”
Forensics, from pg. 1
“I enjoyed every lecture, especially those of John Black (SLED senior
agent) and those in DNA and serology from John Barron (investigator,
Richland County Sheriff’s Department) and Dr. Gray Amick. Every lecturer wanted to be there and is dedicated to their field, which made the class
even more interesting,” says student Heather Herlong.
The class also had labs where the students could put the things they
learned into practice. There were labs on hair, DNA, toolmarks, footwear,
and firearms. During the firearms lab, a blank was fired from a gun, and
students were able to analyze the gunshot residue left on the hand of the
shooter. They were also able to estimate the distance the gun was fired
from a target by chemically analyzing the pattern of gunshot residue deposited on the target. In another session, students dusted and lifted fingerprints.
“I think their favorite class was the fingerprint analysis,” says Dr. Brewer.
Pictures and other evidence from true cases were used during the labs.
The students also learned how to view and evaluate fibers and other materials under microscopes. “I particularly enjoyed the lecture taught by Jeff
Hollifield on hair and fiber analysis,” said rising senior chemistry major
Katherine Nix. She took the class to prepare for Chemistry 622, an analytical forensics course.
“I found CHEM 107 very interesting. Dr. Brewer did a wonderful job
teaching as well as organizing the lectures and labs,” said Nix. “You will be
hard pressed to find a more interesting lab! I loved the course and hope that
it grows in interest,” agrees Herlong.
Morgan Lab Develops Cutting-Edge Forensic Fiber
Analysis Techniques for the FBI
Fiber evidence is frequently used in forensic
laboratories to associate a suspect with a victim or crime scene. “Questioned” fibers are
collected from the crime scene, and “known”
fibers are collected from the suspect. Evidence
fibers are collected through a combination of
picking, scraping, vacuuming, and sometimes
taping clothing and areas of the crime scene,
and they are mounted in a mounting material
on microscope slides for comparison and storage. Questioned and known fibers are compared using a series of microscopic techniques
to determine whether or not the fibers could
have come from the same source. For example,
polarized light microscopy (PLM) can be
employed to determine the generic fiber type
(polyester, acrylic, nylon, cotton, etc.); color,
fiber cross-sectional shape and fiber thickness
are also compared. This analysis is often followed by fluorescence imaging and UV-visible
and fluorescence microspectrophotometry. If
spectra of the known and questioned fibers
match, the hypothesis that the fibers originate
from a common source is not discredited. However, fiber evidence is class evidence (i.e., not
unique), and many fibers from different sources
are often indistinguishable.
With these techniques, fiber examiners can
determine whether a textile fiber is cotton,
polyester, nylon or acrylic, which comprises
more than 90 percent of all forensic fiber evidence collected from crime scenes. They can
also determine whether it is red, blue, yellow,
or green and whether the fiber is skinny, fat, or
has an irregular cross-section. Although this is
a lot of information about the fiber, the problem
is that a red polyester fiber, for instance, may
have been dyed using multiple combinations
of different dyes, and the fiber may have been
dyed by any of a large number of commercial
dyers. Until recently, the tools to distinguish
between such similarly colored fibers did not
exist.
Dr. Stephen Morgan, Dr. James Hendrix,
and a team of postdoctoral, graduate, and
undergraduate researchers have been developing analytical protocols to improve forensic
matching of fiber evidence. The Morgan Lab
research team has built up extensive experience
Undergraduates Allyson Wells (front) and Alison Bush
have mounted several thousand fibers for microspectroscopic analyses in the Morgan laboratory.
in the chemistry and application of dyes and
finishes to textile fibers, as well as in chemical
analysis of fibers and dyes using spectroscopy,
extraction, separations, and mass spectrometry.
With an initial $731,000 from the FBI during
2002–2003, they put together a fiber library that
comprises several thousand dyed textile fibers.
Undergraduates Elizabeth Enlow (presently a
graduate student at UNC Chapel Hill), Jennifer
Kennedy (now in medical school in Tennessee),
Alison Bush, and Allyson Wells have also contributed to these efforts. Multivariate statistics
software for rapid comparisons of fiber spectra
has also been delivered to the FBI for use in
casework and routine quality control. Using
these protocols, the FBI can now effectively discriminate fibers that appear to be the same color.
With $792,000 in FBI funding during 2003–
2004, the Morgan Lab has gone far beyond
forensic discrimination of fibers of the same
color. Graduate students Amy Stefan and Chris
Dockery and undergraduate Samantha Roberson
have employed combinatorial approaches with
a laboratory robot to extract dyes from fiber
samples as small as 2 millimeters in length.
Graduate student Brandi Clelland and postdoctoral researcher Dr. Brittany Hartzell-Baguley
then analyze these extracts by capillary electrophoresis/mass spectrometry. The amounts of
dyes present on a fiber sample and the chemical
identities of those dyes effectively constitute a
“fingerprint” of high discriminating power for
fiber identification.
Fiber evidence collected at crime scenes is
seldom in pristine condition. On the contrary,
textile products items are subjected to a broad
array of environmental conditions during
use. For instance, auto interiors may become
extremely hot in the summer and very cold
in the winter, and the environment may range
from arid to humid. Auto interiors, curtains,
carpeting, and items of apparel are exposed to
sunlight throughout their useful lives. Carpets
and upholstery get spot-cleaned, while items
of apparel are laundered or dry-cleaned many
times. During these “environmental exposures,”
dyes and finishes may be degraded or otherwise
changed in chemical form, or they may be partially or completely removed from a fabric. The
items may also pick up various contaminants,
such as soils and body fluids, and deposition of
refurbishment chemicals may occur during the
cleaning process (i.e., soaps, fabric softeners,
and fluorescent brighteners). As a result of these
environmental exposures, fibers from the same
source may, over time, show differences that the
forensic trace evidence examiners may need to
explain in testimony.
The fiber database is currently being extended to include spectra from a variety of singlecolor and tri-color fibers that have been exposed
to different environmental weathering conditions. With an additional $670,000 from the
FBI, a team of four graduate students (including
Tony Trimboli and Suzanna Heath Hall) and
10 undergraduates (eight from USC, including
Jacob Minsky, Jennifer Yiu, and Heather Taylor;
two from Clemson) contributed to these efforts
last summer. Undergraduates Rachel Hipp and
Drew Krena are correlating spectral differences
in weathered fibers with known photodegradation processes in dyes. For example, after
detergent washing of cotton and nylon fiber
samples, changes in fluorescence due to the
presence of fluorescent brighteners in detergents
can increase discrimination among fibers. This
ongoing work in the Morgan lab will result in
higher reliability matching of weathered fibers
found at a crime scene to pristine-condition
“known” fibers.
Two Faculty Members Retire in 2005
2005 marks the retirement of two revered members of the Department of Chemistry and Biochemistry faculty. Dr. Robert Bly and Dr. Roy
Wuthier will be missed by faculty, staff,
and students.
Dr. Wuthier came to
USC in 1975. He received
his BS in agriculture and
chemistry in 1954 from the
University of Wyoming,
Laramie. He then attended
the University of Wisconsin at Madison, where he
Wuthier
earned an MS in biochemistry. He also received his
Ph.D. in biochemistry from the University of
Wisconsin in 1960.
Throughout his years in the area of biochemistry, Dr. Wuthier has received many research
grants and awards. He has been invited to lecture
at numerous conferences, both in the United
States and abroad. Dr. Wuthier is also a member
of several professional organizations, such as the
American Chemical Society and the American
Society for Bone and Mineral Research.
His research has focused mainly on mineralization during bone development and, more
recently, anticancer agents. “In the past several
years I have taken great pleasure in introducing
a significant number of outstanding undergraduate students to basic research, particularly in the
development of FC101 as an anticancer drug.
The interest and response of these students
has been a major reward to me in itself,” says
Wuthier.
Dr. Wuthier has been an integral part of the
Department of Chemistry and Biochemistry. He
has been a Guy F. Lipscomb Professor of Biochemistry since 1996, and he has recently been
named Guy F. Lipscomb Distinguished Professor
Emeritus.
“He has had a remarkable career at USC.
His research has been cutting-edge as evidenced
by his nearly 30 years of continuous funding by
the NIH. This is an incredible record that can be
matched by few in the biomedical sciences in
this country. His contributions to our teaching
mission have been many,” says Dr. Sodetz, a
member of the biochemistry faculty. Dr. Wuthier
will be missed by the entire department.
Dr. Robert Bly is also retiring from USC.
Though he officially retired from the Department
of Chemistry and Biochemistry in 1995, he has
continued to teach courses each year during the
past decade. Dr. Bly earned his BS in 1951 from
Florida Southern College, and he received an MS
from Northwestern University in 1956. In 1958,
he was awarded a Ph.D. from the University of
Colorado. He was an NIH
postdoctoral fellow at MIT
from 1959 to 1960.
Dr. Bly came to the
University in 1961, and he
served as the head of the
Department of Chemistry
from 1970 to 1973. He
Bly
also held positions as visiting scholar for the Departments of Chemistry at the University of California, Berkeley (1973–1974) and the University of
Wisconsin, Madison (1984).
His research focused on organic and organometallic reaction mechanisms, and he directed
the work of 17 undergraduates, four master’s
candidates, 19 doctoral candidates, and seven
postdoctoral fellows. Dr. Bly was the program
chair of the South Carolina Section of the American Chemical Society from 1967 to 1969.
“Dr. Bly has always been well-liked by people,” says Dr. Willard Davis, former department
head and dean and personal friend of Dr. Bly.
“He and his wife were wonderful neighbors for
more than 40 years.” Dr. Bly and his wife Ruta,
who retired from USC’s Department of Chemistry and Biochemistry in 2002, plan to enjoy their
retirement. They recently spent a long holiday
biking in Europe.
In Memoriam
Dr. Oscar D. Bonner passed away on April 11, 2005. Bonner was born in Jackson, Miss., and attended Central High School there. He received a BS in chemistry in 1939 from Millsaps College, an MS from the University of Mississippi in
1948, and a Ph.D. in physical chemistry from the University of Kansas in 1951.
From 1942 to 1946, Bonner served in the United States Navy during World War
II, and he retired as a lieutenant commander. After completing his Ph.D., Dr.
Bonner became a professor at the University of South Carolina in 1951.
“We needed faculty members from the area of physical chemistry, and we
had been looking for a while,” remembers Dr. Willard Davis, who hired Bonner. “Back then, the president interviewed the entire faculty. Dr. Bonner was
a commander in the Navy, and President Norman Murray was an admiral. I
think that helped O.D.,” said Davis with a laugh.
Bonner was the acting head of the Department of Chemistry from 1959
to 1960 and the head of the Department of Chemistry from 1960 to 1970.
During his term as department head, the Department of Chemistry received
grants to subsidize the construction of the Jones Physical Science Center.
“Before the Jones Physical Science Center, we had one and one-half floors
of another building. We only had two telephones for the entire department.
Moving to the science center was a great change,” says Dr. Robert Bly, who
was hired by Dr. Bonner.
Dr. Bonner’s research during his time at USC represented a significant contribution in the areas of electrolyte solutions, ion exchange, ploy-electrolytes,
and the structure of solvents—particularly water. “He was a very active, loyal,
and hard working member of the faculty. He got along with everyone,” says
Dr. Davis.
Dr. Bonner held the R.L. Sumwalt Endowed Chair of Chemistry from 1970
until he retired as Distinguished Professor Emeritus in 1982.
Dr. Bonner was also active outside of the University of South Carolina. He
was a Fulbright Professor in Germany and South Korea. He also held visiting
professor positions at numerous universities in Europe, Australia, and Canada.
Dr. Bonner was a visiting scientist at Oak Ridge National Laboratory and the
Savannah River Laboratory. He led seminars at universities throughout the
United States.
For 50 years, he was a member of the American Chemical Society
(ACS), and he held positions in ACS at the state, regional, and national
levels. Dr. Bonner served as chair of a Gordon Research Conference on
Ion Exchange. He wrote and co-wrote more than 100 scholarly articles for
respected publications.
“He was always nice, friendly, and people liked him. He would invite
members of the faculty to his house for dinner, and he liked to play tennis with
faculty from physics and other departments at USC,” remembers Dr. Bly.
O.D. Bonner contributed greatly to the Department of Chemistry and
helped form it into what it is today. He directed numerous MS and Ph.D.
students and brought esteem and grants to the department during his time as
department head. We will always be grateful for the ways that Dr. Bonner contributed to the Department of Chemistry. He will be missed.
Department Welcomes New Faculty
The Department of Chemistry and Biochemistry
welcomes five new faculty members in 2005:
Drs. Wayne and Caryn Outten, who are involved
in organic and biochemistry; Dr. Linda Shimizu,
who specializes in organic and biochemistry;
Benjamin Twining, who researches in the area
of analytical chemistry; and Sheryl Wiskur, who
focuses on organic chemistry.
Dr. Caryn Outten
grew up in northeast Philadelphia. She received her
undergraduate degree in
chemistry and biology from
the College of William and
Mary in Williamsburg, Va.
She chose to work with Dr.
Tom O’Halloran at Northwestern University in
Evanston, Ill., for her graduate studies.
Dr. Outten completed postdoctoral studies
with Dr. Val Culotta’s group at Johns Hopkins
University. “Using saccharomyces cerevisiae, or
baker’s yeast, as a model system, my postdoctoral research focused on uncovering the mechanisms of hyperoxia-induced cellular damage and
the mitochondrial defense systems that guard
against oxidative stress.”
At USC, Dr. Outten plans to identify and
characterize antioxidant factors that contribute
to cellular redox homeostasis. “The goals of
my research are to understand how antioxidant
factors are targeted to different intracellular
compartments and how the cell maintains redox
balance in the face of endogenous stresses and
environmental insults. As such, these studies are
designed to improve our understanding of the
impact of oxidative stress on cell fitness, with
strong implications for disorders that perturb
redox balance.”
Dr. Wayne Outten is
from the Richmond, Va.,
area, and he received his BS
in chemistry from the College of William and Mary
in Williamsburg, Va. Dr.
Outten received his Ph.D.
from Northwestern University in Evanston, Ill. There he studied with
Tom O’Halloran. His research “was focused on
understanding copper transport and detoxification in bacteria.”
“At USC I will initially focus on how Fe-S
clusters in metalloenzymes are synthesized in
vivo during environmental stress conditions,
such as oxidative stress. This is a continuation of
work on the suf Fe-S cluster assembly pathway
that I began as a postdoctoral fellow,” says Outten of his plans for his research at USC. “I will
also begin to characterize metal homeostasis
systems in biofilms, which are complex threedimensional structures formed by bacteria in the
environment and during pathogenesis.”
He is looking forward to becoming a part of
the USC faculty. “My long-term goals at USC
are to build a productive research lab and to
become an integral part of the strong faculty
community in the Department of Chemistry and
Biochemistry.”
Drs. Wayne and Caryn Outten are married
and have a son, Bryce, who was born in March.
They will be living in the Shandon area with their
three cats. Caryn enjoys outdoor activities, such
as soccer, volleyball, biking, camping, windsurfing, and canoeing. She also likes to cook—especially sweets! Wayne also enjoys camping, hiking, and a number of outdoor activities. He also
enjoys “focusing [his] biochemistry expertise on
the fine art of home-brewing beer!”
Dr. Linda Shimizu is
no stranger to USC. She has
been a research assistant
professor at USC for several
years, during which time
she developed an externally
funded research program in
the area of supramolecular
chemistry. “The Department of Chemistry and
Biochemistry has been a wonderful intellectual
environment for me, allowing me the opportunity to develop my research interests,” says
Shimizu. She will continue to develop new
building blocks for supramolecular chemistry
while establishing new research objectives in the
area of antibacterial agents and tertiary organized
polymers.
Originally from New Jersey, Dr. Shimizu
received her undergraduate degree in chemistry and German language and literature from
Wellesley College in Wellesley, Mass. She completed her graduate work in the area of peptide
synthesis and conformation at Massachusetts
Institute of Technology with Professor Daniel
Kemp. Subsequently, Dr. Shimizu was an NIH
postdoctoral fellow with Prof. John Essigmann
in the toxicology division at Massachusetts Institute of Technology, where she worked on developing new drugs for prostate cancer.
Dr. Linda Shimizu is married to fellow faculty member Ken Shimizu, and they recently
moved to Shandon with their two children,
Emily and Michael. “With such busy schedules,
we really cherish our family time,” she says.
You might spot the family out biking or playing
at the parks nearby. The children are especially
impressed with all the tall trees in Shandon, and
Michael, 3, has decided that their new house “is
in the forest.”
Dr. Benjamin Twining
comes to USC from Yale
University. He received his
AB in 1997 in environmental science and public policy
from Harvard University in
Massachusetts. “I spent a
semester doing my senior
thesis research in the Turks and Caicos Islands
in the Carribbean, and this cemented my desire
to pursue graduate work in oceanography.” In
2003, he graduated with his Ph.D. in coastal
oceanography from Stony Brook University in
Stony Brook, N.Y. After graduating, Dr. Twining moved to Connecticut to do his postdoctoral
studies with Gaboury Benoit at Yale University.
“My research is focused on the interactions
between trace metals and plankton, single-celled
organisms found in aquatic environments,” says
Twining. “I have focused my efforts on adapting
and utilizing state-of-the-art analytical tools to
address questions of metal bioavailability, accumulation, trophic transfer, and recycling within
varied aquatic systems.”
At USC, Dr. Twining plans to expand on his
research. He is also excited about the opportunity to work with the students in the Department
of Chemistry and Biochemistry. “There will be
exciting opportunities for both undergraduate
and graduate students in my lab, including fieldwork in coastal and open ocean environments.”
Dr. Twining is married and has a 2-year-old
daughter and a son due in September. His wife,
Christine, will be starting an adult endocrinology
fellowship at the USC School of Medicine in
summer 2006. He enjoys cycling, soccer, tennis,
and windsurfing in his free time. He also enjoys
singing and would like to be involved with the
choral department at USC.
The Department of
Chemistry and Biochemistry also welcomes Dr.
Sheryl Wiskur. She grew
up in Michigan and began
her undergraduate studies at
the University of Michigan,
Flint. She graduated with
her BS in 1997 from Arizona State University.
After that, she moved to the University of
USC Creates the Jerome D. Odom
Fellowship in Chemistry
The Office of University Foundations and many individual donors
have joined together to create a
fellowship honoring Jerome D.
Odom, who has returned to the
Department of Chemistry and
Biochemistry this year. For the
past seven years, Dr. Odom served
as the vice president for academic
affairs and provost. The department
is very happy to have him back
full time. The fund was formed
to recognize Dr. Odom’s diligent
work in the areas of administration,
research, and instruction.
The fellowship is awarded by
Dr. Odom congratulates fellowship recipient Elizabeth Tucker
the Department of Chemistry and
Biochemistry Scholarship Committee to worthy undergraduate or
graduate students pursuing degrees in chemistry or biochemistry and conducting scholarly activities
consistent with the South Carolina Research Centers of Economic Excellence program in polymer
nanocomposites.
The first recipient of the Odom fellowship is Elizabeth Tucker. She is a first-year graduate student, and the fellowship enabled her to do summer research in Dr. Linda Shimizu’s lab. “I was very
surprised to learn that I was the recipient of the Jerome D. Odom Fellowship, and I am very grateful
for it. It was one of the factors that influenced my decision to attend USC. This summer I have been
working in Dr. Linda Shimizu’s lab trying to synthesize bis-urea macrocycles, and I am looking forward to beginning my studies at USC,” says Tucker.
Contributions or pledges to the Jerome J. Odom Fellowship in Chemistry can be sent to the
Department of Chemistry and Biochemistry.
Texas, Austin, where she earned a Ph.D. under
the direction of Eric Anslyn. “My work there
consisted of developing sensors for carboxylates and diols,” says Wiskur. From 2003–2005,
Dr. Wiskur completed postdoctoral studies at
the Massachusetts Institute of Technology. “I
worked with Greg Fu on palladium and asymmetric reactions.”
Dr. Wiskur’s research focuses on synthetic
organic methodology, “where organic reactions
are developed using small organic nucleophilic
catalysts. These modernized transformations
offer a replacement to traditionally metal catalyzed reaction, ultimately providing new tools
for synthetic chemists. Even though organocatalyzed processes have been known for quite some
time, only recently has an increased interest
been shown. The advantages of organocatalyzed
reactions are eliminating trace metal contaminants, reduction of cost, and functional group
compatibility. Some examples of small organic
catalysts are amino acids, guanidines, natural
product alkaloids, and thiazolium compounds.”
At USC, Dr. Wiskur plans to expand her
research. “In a collaborative project, we are also
exploring the synthesis and detection of marine
natural products that are of interest due to their
biological activity and prevalence in the marine
environment.”
In her free time, Dr. Wiskur enjoys running,
reading, cooking, watching movies, and, most of
all, relaxing!
The Department of Chemistry and Biochemistry welcomes our new faculty members and
looks forward to the research they will conduct
at USC.
College, from pg. 1
important years of a University education. The
department is charged with preparing students
not only to go on to success in their program
and major but also to attain success in other
undergraduate majors in the college as well as in
undergraduate professional school curricula in
pharmacy, nursing, and engineering. The department partners with its colleagues in other departments, schools, and colleges to create a dynamic
and vital undergraduate educational experience.
The Department of Chemistry and Biochemistry excels in teaching, in doctoral education,
and in research. The department is poised for
involvement in a number of the new faculty
hiring initiatives of the University. This year,
the department added new centenary professors and is involved in a number of new faculty
excellence initiatives and centers of economic
excellence proposals. The commitment to interdisciplinarity and cross-department and crosscollege collaboration makes the Department
of Chemistry and Biochemistry a prototype of
what the new college represents to the University. Indeed, we are building the new college on
the solid foundation Department like Chemistry
and Biochemistry.
On behalf of this new college, I promise that
we will work hard, and we will listen.
To our students, I promise an excellent
education.
To the faculty, I promise a context where
they can grow as scholars and teachers.
To our alumni and friends, I promise that we
will stay connected and welcome them when
they visit.
I look forward to creating the new college
with all of you. Our shared passion for combining great teaching and great research is helping
us build one of the great arts and sciences units
in the world.
Think of the possibilities.
Looking Back—Max Gergel
Max Gergel, who graduated with a BS in chemical engineering from USC in 1942, presented
a well-attended seminar on Feb. 17, 2005. The
seminar was titled “My 7 Years at the University of South Carolina and 58 Years in Organic
Chemistry—an Interim Report.” Gergel entertained and informed students with stories about
his life in the world of chemistry.
Gergel got his start in chemistry while he
attended Columbia High School. He was asked
by a teacher, Mr. Czarnitsky, about what he
wanted to do with his life. Czarnitsky suggested
chemistry, and Gergel ran with the idea. While
in high school, he and a group of friends were
involved in a challenge with USC students to
see who could make the greatest quantity of
luminal, a new substance at the time, in the
shortest amount of time. The high schoolers lost
the contest, but they found career goals. Gergel
notes that several other prominent members of
the medical and chemical fields were influenced
by Mr. Czarnitsky.
“I entered the University of South Carolina
in 1938 with the McKissick Fellowship,” says
Gergel. He worked with Dr. Copenhaver, who
Gergel fondly remembers as a father figure. His
favorite memory of his time here is this: “After
my freshman year, I didn’t think I would be able
to afford to return to USC, but Dr. Lipscomb
had taken notice of me and my hard work.
He offered me a job as an assistant in his lab.
That position usually went to a senior. I was so
grateful to him.” When asked about all of his
achievements, Gergel says that he is most proud
of graduating Phi Beta Kappa from USC. This
honor was almost unheard of for chemical engineering majors at the time.
In his senior year at Carolina, he began the
Columbia Organic Chemicals Company. In
the first year of the company’s existence, they
were contracted to work with the Manhattan
district engineers. They worked in the area of
research and production. Dr. Willard Davis
and Paul Tarrant (University of Florida) also
helped on the project.
During the past 30 years, Gergel has been a
consultant to a number of companies, including
Mitsui, Mitsubishi, Dead Sea Works, Fluorochem, and many others. He has also given more
than 300 lectures at companies and universities
throughout the United States, Europe, and the
Middle East. He has also written two books:
Excuse Me Sir, Would You Like to Buy a Kilo of
Isopropyl Bromide? and The Ageless Gergel.
Gergel has also been a member of the American
Chemical Society (ACS) for 65 years and has
lectured on three ACS tours. He is also active in
the American Institute of Chemists and Alpha
Chi Sigma.
Gergel claims that the key to his lifetime of
success has been the friendships he has made with
the people in his field. He mentions in his first
book that seeing friends at ACS meetings became
his “meat and bread” because of the business contacts he was able to meet through them.
The one piece of advice that Gergel wants
to pass on to chemistry students is to make the
most of their education. “Only the good are chosen. Broaden your education, and go as far in it
as you possibly can,” he says. He recommends
getting the highest degree possible and to learn
in a variety of places.
Gergel is still active in the world of chemistry. He currently has four consulting projects that
he is working on, including Prochem in Rock,
Ill., and he continues to lecture students like
he did this year at USC. He also has three new
books in the making: The Early Gergel, Volumes
I and II, and The Last Gergel.
His hard work and knowledge have made
him a successful businessman, but his friendliness and charming manner have made him a
successful person. Dr. Richard Adams of the
Department of Chemistry and Biochemistry
adds, “He is witty and charming and has written
some wonderful books about his experiences
at USC. He is very well liked by students and
faculty alike.”
Contribute to
“Looking Back”
If you’re an alum of the chemistry
department and would like to share the
story of your life in chemistry beyond
USC, please feel free to write us at
USC Chemist,
c/o Department of Chemistry and Biochemistry, University of South Carolina,
Columbia, SC 29208.
We look forward to hearing from you!
From Young Turk
to Old Goat
By Robert L. Cargill Jr.
When I joined the chemistry faculty at the University of South Carolina in 1962, I thought I
was pretty hot stuff. After all, I had a Ph.D. from
MIT and had just spent two years at UC Berkeley
as a postdoctoral fellow. I was made to understand that my success (tenure and promotion) at
Carolina would be dependent upon my research
(publications, grants).
One can imagine my reaction when on weekends, during home football games, and during
holiday periods, especially the long Christmas
recess, I would go to the University library to
prepare research proposals only to find the library
CLOSED.
I accosted the librarian, the dean, and the
provost. How could I be expected to write grant
proposals when I could not get in the library?
Naturally, I had other pressing duties during regular library hours. I expected the library to be available to me and to other aggressive young assistant
professors who wanted to launch brilliant careers
(the Young Turks) on a 24-hour basis every day,
including holidays.
My outbursts were met with what I view in
hindsight as remarkable patience, although my
view then was very different. I could not be made
to understand budgets and other administrative
problems. I just wanted to have my way. If this
sounds like the behavior of a spoiled child, it was
(and is not atypical of assistant professors).
When the University built a new Physical Sciences Center in 1967, Dean H.W. Davis led the
fight to have a Science Library in the new building. Little did I understand that part of his motivation was to teach me a lesson. I played into his
hands just as he expected. I pressed for the formation of a committee of users of the new Science
Library. The dean agreed and named me its chair.
My ego swelled beyond its already bloated size.
No later than a week after the dedication of the
new building and the opening of the new Science
Library, my colleagues, who only wanted what
I had pressed for, descended on me, demanding
longer hours, increased subscriptions, more, and
better service. I quickly learned how the dean
felt during my visits to demand more. I had to
explain to my now hostile colleagues why our
limited budget did not permit all those things
that we had demanded.
The brash Young Turk had become the Old
Goat.
Alumna Delana Nivens Speaks
About her Work in Nanotechnology
On Nov. 19, 2004, Dr. Delana Nivens (Ph.D.
1998) presented an education research seminar
titled “Implementation of Nanotechnology Vertical Threads into the Undergraduate Chemistry
Curriculum at AASU.” Dr. Nivens, an alumna of
Dr. Mike Angel’s lab, has been an assistant professor of analytical chemistry and biochemistry
at Armstrong Atlantic State University (AASU)
since 2001. Prior to this appointment, she was
a visiting assistant professor at AASU for one
year and a postdoctoral fellow for two years at
the Naval Research Laboratory under the direction of Dr. Frances S. Ligler and Dr. David W.
Conrad. Dr. Nivens is active as a reviewer for
the NSF in the areas of analytical and surface
science, small business innovative research,
nanoscale science and engineering education,
and course curriculum and laboratory improvement. She is also a panelist on the 2007 American Chemical Society Analytical Chemistry
Examination Committee. In 2004, she organized
a well-attended symposium at PITTCON titled
“Undergraduate Research and Education: A
Showcase of Faculty at Primarily Undergraduate
Institutions.”
The lecture was an overview of her work in
developing nanotechnology exercises for use at
all levels of the undergraduate chemistry and
non-science curriculum. The exercises consist
of both new experiments as well as modifications of traditional laboratory experiments to
give them a “nano” focus while still teaching the
same concepts. The introduction of nanotechnology concepts is via a series of “vertical threads”
where students can revisit a specific nano system
(such as magnetite, ZnS, CdS, MoS2 or CeO2)
a number of times in their various laboratory
courses from freshman to senior undergraduate
level. This allows the students to build on concepts related to nanoparticles they have learned
in previous courses. Work on this project by Dr.
Nivens and her Co-PIs, Dr. Will Lynch (AASU)
and Dr. Ron R. Williams (Saginaw Valley State
University), was funded by the National Science
Foundation Nanotechnology in Undergraduate
Education program (CHE/NUE 0303994), the
University System of Georgia, International
Paper Company, and the American Chemical
Society Project SEED program.
The goals of the NUE project are to introduce students to the nanoscale: the basic concepts of nanoscale science and how nanoparticles differ from bulk particles and how
nanoparticles might be used in industry and
research. In addition, the project aims to stimulate and fund undergraduate research projects in
the rapidly expanding area of nanotechnology.
For example, an instrumental analysis laboratory, which introduces students to UV-VIS,
IR, Fluorescence and GC/MS will first have
students collect UV-VIS spectra of nanoparticles during their formation. Subsequently,
the students use that information to calculate
particle size. Students compare the spectra and
the photocatalytic efficiency of bulk and nanobased materials. They later collect IR spectra of
dry nanoparticle powders containing stabilizing surfactants or polymeric coatings, collect
fluorescence spectra of the nanoparticles, and
even titrate the nanoparticles with fluorescence
quenchers or enhancers. In some instances,
they use the nanoparticles to perform a reaction
(typically as a photocatalyst) and monitor the
products by SPME-GC/MS. Similar experiments
have been designed for physical chemistry and
for inorganic chemistry courses.
Undergraduate research students are exploring not only the photodegradation of halogenated aromatics, but they also are investigating
nanotechnology at the interface of biology. First,
they are examining the effect of photocatalytic
semiconductor nanoparticles on both DNA and
bacteria. Results show that while nanoparticles
may be useful in catalyzing the degradation
of halogenated aromatics, they are quite toxic
to bacteria, especially when exposed to light.
These results could have positive implications
for decontamination of samples but also negative implications by harming naturally occurring
bacteria in the environment. Undergraduate
students are examining biological (green) methods for synthesizing nanoparticles. Dr. Nivens
is currently pursuing funding for these projects
through the NSF Nanoscale Science and Engineering Education program, the NSF’s Research
at Undergraduate Institutions program, and the
Environmental Protection Agency.
USC Welcomes NanoCenter Director
On July 28, 2005, Dr. Harris
Pastides, vice president for
research and health sciences
at USC, announced that Dr.
Thomas Vogt would assume
the position of USC NanoCenter director.
Vogt has a strong background in chemistry and physics, and he is an
expert in crystallography and structural and
synthetic chemistry, as well as diffraction techniques using neutrons and X-rays. His research
focuses on hydrogen storage materials, an area
that is essential to hydrogen fuel cell technology,
a focus of USC research.
Having received a doctorate from EberhartKarls Universität in Tübingen, Germany, Vogt
joined the Brookhaven National Laboratory in
1992. He helped plan the Brookhaven Center for
Functional Nanomaterials, which is scheduled to
begin operations in 2007.
Vogt is a member of the American Chemical
Society, American Physical Society, Electrochemical Society, and the American Association
for Advancement of Science Materials Research
Society. He has two U.S. patents and two pend
ing patent applications.
Vogt will also join the Department of Chemistry and Biochemistry as a tenured professor.
His appointment at the NanoCenter will begin
on Oct. 1, 2005. He will replace Dr. Richard
Adams, who successfully established the NanoCenter in 2001. The center is used by several
departments at USC and is essential to the
research of more than 40 professors.
This appointment reflects USC’s growth in
nanoscience and as a research institution, as well
as the state’s commitment to seek top research
scientists at its institutions.
Department
It’s New Science But Is
Alumna
It Patentable?
Receives Award By Dr. Jeff Lindeman
Mary Weir Lipton (Ph.D.
1993) received the University of South Carolina College of Arts and Sciences
Outstanding Young Alumna
Award in 2005. This award
is presented to an alumnus
40 years of age or younger.
It recognizes outstanding achievement in science, academia, government, and/or not-forprofit organizations, and/or outstanding contributions to society, and/or outstanding service to
the University.
Dr. Lipton received her Ph.D. in biochemistry under the instruction of Dr. Bruce Dunlap.
She is currently a senior research scientist at
Pacific Northwest National Laboratory, and she
serves as adjunct professor at Washington State
University (TriCities). She is best known for
her research in developing and applying new
mass spectrometry-based technologies for the
global proteomic characterization of biological
systems. These new methodologies represent
a major advance in the field of proteomics and
enable biological systems to be globally characterized without the need for two-dimensional
gels or other fractionation methods. Dr. Lipton’s
research has focused on characterizing both
environmental microbes important to bioremediation and energy production schemes and on
pathogenic microbes with relevance to developing detection technologies and vaccines.
Mary Lipton has authored and co-authored
more than 30 peer-reviewed publications and
is a member of numerous societies, including ACS, Radiation Research Society, and the
Association of Women in Science. In 2001 she
received the Battelle’s Woman of Achievement Award, and she earned six Outstanding
Performance Awards between 2000 and 2004.
Additionally, she received Radiation Research
Travel Awards in 1994 and 1995, and she has
been invited to lecture at many national and
international meetings. Her research has been
funded by grants from several institutes totaling
almost $5 million.
The Department of Chemistry and Biochemistry is very proud of Dr. Lipton and wishes her
continued success in her future research.
Dr. Jeff Lindeman presented a seminar titled “It’s
New Science But Is It Patentable?” on April 1,
2005, at USC. Lindeman graduated from USC
with a Ph.D. in 1988, and he received his JD
from Georgetown University Law Center in 1992.
Dr. Lindeman is a partner with Nixon Peabody in
Washington, .D.C., where he specializes in patents. He spoke to USC students about the patent
process, and he graciously submitted the following article for this publication.
Inventions come from solving problems. An
invention is new technology that solves a problem. In chemistry, this may be a new compound
to treat a disease or an improved process. Patents
are intellectual property rights in new technology, in inventions. While a patent is a legal
document, it is also a scientific document. Within
the legal framework of a patent an inventor
describes the invention and defines the technology property right. How one describes and defines
the invention often determines the strength and
worth of a patent.
There are two fundamental parts to a patent: the specification and the claims. Each has
a different function. The specification describes
the invention and includes a written description,
drawings and, typically, examples. The claims
delineate the patented invention thereby defining the intellectual property right. Whether or
not something infringes on a patent depends on
whether or not it comes within the scope of the
patent claims.
Understanding the invention and the scientific
principles underlying it is the first step to preparing a patent application. Knowing why the invention is different from what was done before is the
second. From that one builds a theory for patentability and establishes a theme for the patent to
describe the invention. To obtain broad patent
coverage, the patent claim should also embody
these scientific principles and themes.
The Patent Specification—35 USC § 112,
First Paragraph
The specification must “describe the invention.”
Typically a background section provides context
for the invention. The background section can
describe the problem the invention solves and discuss prior attempts to address the problem. The
specification contains the technical description of
the invention. It also functions as a “dictionary”
for the words in the patent claim.1 For that reason
10
the language of the technical description must be
carefully chosen and be consistent with that of
the patent claims.
The specification must also “enable” the
invention, that is, teach a person skilled in the art
how to make and use the invention. This is the
purpose of the written description. The specification is not written to the public at large but to
those skilled in the relevant art. Real working
examples of the invention are a good way to
enable the invention. The specification describes
different embodiments of the invention to support
broader claims, beyond the specific embodiments
in the examples. For instance, the examples may
show methyl and propyl derivatives, but the
specification can generally describe C1-C8 alkyl
derivatives. the claimed invention could then be
the C1-C6 alkyl derivative.
The Patent Claims—35 USC § 112,
Second Paragraph
Patent claims are the numbered paragraphs at
the end of a patent. The most important part of a
patent, they are the measure of the property right
in the patented technology. Patent claims do not
describe every aspect of the invention but, when
well written, describe only those aspects which
delineate the boundaries of the invention and differentiate it from the “prior art.” For patents, the
language of the claims controls. It is, therefore,
very important that the inventor review and be
satisfied with language on the patent claims.
By statute, the patent claims must particularly
point out and distinctly claim the subject matter which the applicant regards as his invention.
This is essentially a requirement for precision
and definiteness of claim language. The language
of the claims must make clear what they encompass.2 Stated somewhat differently, the claims
must be “sufficiently precise to permit a potential
competitor to determine whether or not he is
infringing.”3 Clarity in claim language does not
necessarily preclude broad patent protection. It
does give robust patent claims.
Although patent claims are first presented in
the patent application and then examined by the
patent examiner, the claims are often not fully
tested until a patent is litigated. During examination, the claims are given their broadest reasonable interpretation, consistent with the specification. The inventor and the patent examiner
discuss the meaning of the patent claims and the
ALUMNI NEWS
David B. Baily (Ph.D. 1980) resides in West
Chester, Ohio. He spent almost 18 years in
industrial research and development analytical settings. Seven years ago, David radically
changed his life and is now an Episcopal priest
in Cincinnati.
William G. Burns (MS 2004) works at Brockmann Ind. in Hilton Head Island, S.C. He is in
the technical sales department.
Matthew Laskoski (Ph.D. 2002) and Holly
Lynn Ricks (Ph.D. 2004) were married on May
7, 2005, in Abita Spring, La. Both are research
chemists with the Naval Research Laboratory in
Washington, D.C. They reside in Alexandria, Va.
Wendy Drane Plessinger (MS 1995) works
with Parenta Pharmaceuticals in West Columbia,
S.C. Parenta is a contract manufacturer of injectable medicines.
Jim Rogers (Ph.D. 1990) is the marketing manager for India Pacific. He works for Flint Ink in
the Melbourne, Australia, branch. He resides in
Black Rock, Australia.
scope of the invention they define. From the USPTO’s perspective, a patent applicant always has
the opportunity to amend the claims and broad
interpretations by the examiner, reducing the possibility that the claim, once a patent issues, will be
interpreted more broadly than is justified.4
In patent litigation, determining infringement
involves two-steps: (1) interpreting the claims and
(2) determining whether the accused object or
process is covered by the claims as interpreted.5
The interpretation of a patent claim is a question
of law for the court (the judge) to decide, not one
of fact for the jury to decide.6 In litigation, claim
language is to be interpreted as one reasonably
skilled in the art would have interpreted the claim
at the time of invention.7 The person of ordinary
skill in the art is deemed to read the terms of a
claim, not only in the context of the patent claim
but also in the context of the entire patent.8 The
importance of carefully choosing and consistently
using the language to describe and claim the
invention cannot be overemphasized. If the specification describes the invention in broader terms
Jeffry Schumm (Ph.D. 1993) is the global
director of Market, Applications & Business
Development for Industrial Dielectrics, Inc. of
Noblesville, Ind. He lives in Lafayette, Ind., with
his wife, Kim, and their three children.
Donald Sens (Ph.D. 1976) is currently a professor of surgery at the University of North Dakota.
His current NIH research involves the role of
metallothioneins and heat shock proteins in
heavy metal toxicity in the kidney and role of
metallothionein in neoplasia.
Mary Ann Sens (Ph.D. 1976) is currently professor and chair of pathology at the University
of North Dakota. She obtained her MD from
MUSC in 1981 and was trained in anatomic and
forensic pathology. She is now active in NIH
research in breast cancer, metallothioneins, and
the education of medical and health science
students. She is also the coroner of Grand Forks
County, N.D.
Tracie G. Sheehan (Ph.D. 1990) is currently
employed with the Sara Lee Corporation. She
resides in Cincinnati, Ohio.
Dimitra Stratis-Cullum (Ph.D. 2000) was married in 2001 to Brian Cullum (Ph.D. 1998).
Dimitra is a federal employee at the U.S. Army
Research Laboratory.
Carol Clark Stork (BS 1968, MAT 1973)
works at the University of South Carolina in
the Department of Chemical Engineering. She
resides in Columbia, SC.
Edmund William Svastits (Ph.D. 1986) currently lives in Gainesville, Fla. He is the senior
environmental data manager at CH2M HILL.
Xiaoyou Xu (Ph.D. 2004) lives in Humble,
Texas. He is working with NanoComposites
Inc., in Houston as a senior research scientist.
Muhammed Yousufuddin (BS 2000) received
his Ph.D. from the University of Southern California. He specializes in chemical crystallography, mainly solving the solid-state structures of
chemically interesting small molecules and proteins based on single crystal diffraction patterns
from X-rays and neutron beams.
than the patent claims, the claims are generally
interpreted as being outside the patent claims. The
unclaimed subject matter is available for public
use without infringing on the patent.
(Endnotes)
Conclusion
Inventions come from solving problems. A patent
secures an inventor’s intellectual property right
to an invention. A patent is not merely a legal
document; it is a scientific document as well.
You can’t leave the science out. By statute, the
patent specification must describe the invention
while the claims must particularly point out the
invention to be patented. Because they define the
patent property right, careful consideration must
be given to the language of the claims. To obtain
strong patent protection, the language used to
describe the invention in the specification should
be consistent with the language of the claims.
Inconsistency or differences in language can limit
the scope of the claims and, thereby, the patented
intellectual property.
3 Exxon Research and Engineering Corp. v. U.S., 265 F.3d
1371, 1375 (Fed. Cir. 2001) citing
11
1 Phillips v. AWH Corp., Nos. 03–1269 and 03–1286,—F.3d—,
2005 WL 1620331 (Fed. Cir. July 12, 2005).
2 PPG Industries, Inc. v. Guardian Industries Corp., 75 F.3d
1558, 1562 (Fed. Cir. 1996) (citations omitted).
Miles Labs., Inc. v. Shandon, Inc., 997 F.2d 870, 875 (Fed. Cir.
1993).
4 Manual of Patent Examining Procedure (MPEP) § 2111.
5 Omega Eng’g, Inc. v. Raytek Corp., 334 F.3d 1314 (Fed. Cir.
2003); Fromson v. Advance Offset Plate, Inc., 720 F.2d 1565,
(Fed. Cir. 1983).
6 Markman v. Westview Instruments, Inc., 517 U.S. 370, 384
(1996); Gechter v. Davidson, 116 F.3d 1454, 1457 (Fed. Cir.
1997); Vitronics Corp. v. Conceptronic, Inc., 90 F.3d 1576, 1582
(Fed. Cir. 1996).
7 Specialty Composites v. Cabot Corp., 845 F.2d 981, 986 (Fed.
Cir. 1988) (quoting Loctite Corp. v. Ultraseal Ltd., 781 F.2d
861, 867 (Fed. Cir. 1985)).
8 Phillips v. AWH Corp., Nos. 03–1269 and 03–1286,—F.3d—,
2005 WL 1620331 (Fed. Cir. July 12, 2005), slip op. p. 10.
2004–2005 Academic Year Highlights
Department of Chemistry and
Biochemistry
Appointment of New Faculty
Dr. Caryn Outten, assistant professor
Dr. Wayne Outten, assistant professor
Dr. Linda Shimizu, assistant professor
Dr. Benjamin Twining, assistant professor
Dr. Thomas Vogt, professor and director of USC
NanoCenter
Dr. Sheryl Wiskur, research assistant professor
Distinguished Professor
Appointments
Dr. Thomas Bryson, distinguished professor
Dr. Jerome Odom, distinguished professor
Dr. Roy Wuthier, Guy F. Lipscomb Sr. Distinguished Chair Emeritus
Reappointments of Distinguished Professors
Dr. John Dawson, Carolina Distinguished Professor
2005 State Service Awards
Dr. Richard Adams, 20 years of service
Mr. Bruce Corley, 20 years of service
Dr. Mark Berg, 10 years of service
Dr. Timothy Shaw, 10 years of service
Editorial Board Appointments
Dr. John Baynes was appointed to the Editorial
Board of the Journal of Biological
Chemistry for a four-year term.
Dr. Catherine Murphy was named to the Editorial Advisory Board for the American Chemical
Society (ACS) journal NanoLetters for 2005–
2007.
Dr. Qian Wang was named the America regional
editor for Letters in Organic Chemistry.
Faculty Awards and Honors
Dr. Richard Adams received the Carolina Trustee
Professorship.
Dr. Richard Adams was awarded the Henry J.
Albert Award sponsored by the International
Precious Metals Institute (IPMI) and the Engelhard Corporation.
Elsevier/Harcourt has announced the publication
of the second edition of Dr. John Baynes and
Dominiczak’s textbook: Medical Biochemistry.
The first edition, published in 1999, has been
translated into Chinese (Taiwan), Greek, Italian,
and Portuguese.
Dr. John Dawson was appointed chair of the
2005 Metals in Biology Gordon Research Conference held in Ventura, Calif., in January 2005.
Dr. Catherine Murphy was named to the Advisory Board for Chemical Communications for
2005–2006.
Dr. Catherine Murphy received the Russell
Research Award for Science, Math, and Engineering.
Dr. Jerome Odom received the USC Educational
Foundation’s Outstanding Service Award.
Dr. Ken Shimizu was awarded a fellowship from
the Japan Society for the Promotion of Science
(JSPS) to support his sabbatical work at Kobe
University, Japan.
Dr. Qian Wang and Dr. George Handy were
awarded the student-nominated Two Thumbs
Up Award. It is given to faculty members whose
efforts have made a difference in the success of
students with disabilities.
Dr. Hanno zur Loye was named president-elect
of the South Carolina Academy of Sciences.
Anthony Boccanfuso was elected “memberat-large” for the American Association for the
Advancement of Science Section (AAAS) on
Industrial Science and Technology.
Dr. zur Loye Introduces Chemistry to Third Graders
In April 2005, Dr. Hanno zur Loye visited Mrs. Burkett’s third grade class
at Hammond Lower School, where his son attends. He introduced chemistry to the students through fun experiments. Dr. zur Loye froze balloons,
racket balls, and gloves with liquid nitrogen. He made nylon and performed color-changing reactions. He also made silly putty that the students
were able to keep, and he gave out periodic tables. The letters below show
that Dr. zur Loye could have inspired several young chemists!
“I am so glad you came to Hammond third grade! My favorite thing
was when you froze the glove with nitrogen (liquid). I did not expect the
glove to break when it hit the floor! I had always wanted one of those
adorable little moles! P.S. I love chemistry!”
“I really enjoyed seeing all the chemical reactions. My favorite one was
the one that changed colors. I wish you could have showed us some more.
It was very fun!”
“Thank you for coming to our school. I really liked the experiment
where you made the balloons freeze and then blow back up. I think the
moles are real cool!”
“Thank you for coming to Hammond school. I loved every part of it. Is
your mascot a mole? It was cool when you made the long line of chemicals!”
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Student Highlights
2005 Science Fair Winners
Junior Division:
Sara Scoggins, First Place
Jessica Truesdale, Second Place
Brett Taylor, Third Place
Genevieve Lyke, Honorable Mention
Cole McCarter, Honorable Mention
Rhonda Brown, Honorable Mention
Senior Division:
Patrick Hankins, First Place
Melanie Clemenz, Second Place
Drew Carter, Third Place
Undergraduate Awards
American Institute of Chemists
Foundation, Inc. Award:
Ross Nesbit
American Chemical Society,
Division of Analytical Chemistry
Award: Jason Wheeler
College of Arts and Sciences
Senior Year Scholarship: Allyson
Wells
CRC Press Freshman Chemistry
Award: Christa Campbell
CRC Press Freshman Chemistry
(Honor) Award: Julie Richardson
Discovery Day 2005 Awards:
Rachel Hipp, Thomas Styslinger,
Mary Jo Manuse, Samantha
Roberson
Harper Award: Anne Ellefson
Hiram and Lawanda Allen
Award and the South Carolina
Section of the American Chemical Society for Performance as
the Senior Outstanding Undergraduate Chemistry Major
Award: Samantha Roberson
Howard Hughes Undergraduate
Research Summer 2005 Award:
David Smith
Hypercube Scholar Award:
Anand Pariyadath
Joseph W. and Julia L.
Bouknight Award: Christa
Campbell, Kristy Schleibaum
Merck Index Award:
Meredith Tershansy
May 2005
Lisa Alexander
Heather Bass
Kevin Brotherton
Jacquie Campbell
Brian Gander
Renee Genova
Katarzyna Glab
Neal Goodbar
Benjamin Holladay
Mary Jo Manuse
Eli Muniz
Ross Nesbit
Anand Pariyadath
Sharlee Reed
Samantha Roberson
Daniel Stevenson
Demetria Strauch
Elizabeth Sutton
Bryan Vasser
South Carolina Section of the
American Chemical Society Outstanding Undergraduate Award:
Katarzyna Glab
Victor W. Laurie Junior Year
Scholarship: Benjamin Garrett
Victor W. Laurie Senior Year
Scholarship: Danielle Sweetapple
The Outstanding Achievement
and Student Triumph Award
(TOAST): Mary Jo Manuse,
Kathryn Perrine, Samantha
Roberson, Bryan Vasser
2005 Phi Beta Kappa Nominees:
Stephen Barr
Alison Bush
Anne Ellefson
Amber Hatfield
Daniel Heenan
Lane Henderson
Jason Wheeler
Brian Gander
Ross Nesbit
Anand Pariyadath
Eugenia Senn
Demetria Strauch
Jonathan Wooten
Jennifer Yiu
Undergraduate
Scholarships
2004–2005
Alumni Scholarships
Anne Ellefson
Sally Stephens
Meredith Tershansy
Athletic Grant
Gregory Reece
Joseph W. and
Julia L. Bouknight Scholarship
Daniel Stevenson
2004–2005 American Chemical
Society (ACS) Officers
Mary Jo Manuse, Co-president
Samantha Roberson, Co-president
Bryan Vasser, Vice President
Kathryn Perrine, Secretary
Robert C. Byrd Scholarship
Elizabeth Enlow
Jason Wheeler
Jonathan Wooten
Chemistry BS Graduates
Carolina Scholars
Bradley Hocking
Elizabeth Sutton
Jason Wheeler
August 2004
Matthew Baker
Jonathan Coe
E. Joy Kingsford
Aubrey Lemley
Vu Hoa Van
Melanie Williams
Jovan Wright
Chemistry Discretionary
Scholarship
Anne Ellefson
Andrew Spencer
Engineering Scholarship
Benjamin Garrett
December 2004
Shayla Dorsey
Manushi Patel
Douglas Perkins
Kathryn Perrine
Nicholas Ruggiero
Estimated Scholarship Assistance
Monica Gaynor
Thuy Ho
Matthew Keidel
Kimberly Painter
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Douglas Perkins
Butch Sokolowski
Faculty/Staff Dependents Scholarship
Nathaniel Krueger
Anand Pariyadath
Allyson Wells
Kevin Yehl
Honors College Scholarship
Thomas Styslinger
Hope Scholarship
Jonathan Davis
James A. Hicks Scholarship
Kimberly McNeil
Legacy Scholarship
Mary Jo Manuse
Demetria Strauch
Heather Taylor
Jason Wheeler
Library Scholarship
David Coolidge
Kimberly McNeil
Julie Richardson
Andrew Spencer
LIFE Scholarship
Ashley Aylesworth
Anna Branham
Julie Brown
Alison Bush
Jacqueline Campbell
Walter Cantwell
Kristen Catchings
Dana Corum
Travis Deason
Thomas Edwards
Daniel Heenan
Rachel Hipp
Steven Jordan
Nathaniel Krueger
Christina Lockhart
Joshua Martin
Kimberly McNeil
Bryan Oliver
Cheri Perrine
Sharlee Reed
Samantha Roberson
Tyler Roberts
Berry Roberts
Da’Trice Sims
John Smith
Kristen Sprouse
Student Highlights (cont.)
Sally Stephens
Daniel Stevenson
Demetria Strauch
Bryan Vasser
Shakeena Wallace
SCAMP Grant
Shayla Dorsey
Christina Lockhart
Perry McGriff
McNair Scholarship
Kyle Raker
Science and Mathematics
Scholarship
Samantha Roberson
Men’s Soccer Scholarship
Gregory Reece
Springs Foundation Loan
Perry McGriff
National Merit Scholars
Benjamin Garrett
Trustees’ Endowment Scholar
Matthew Skiles
Navy ROTC Scholarship
Matthew Keidel
Tuition and Fees Scholarship
Douglas Perkins
Non-University Scholarship
Michael Bechtold
Christa Campbell
Anne Ellefson
Nathaniel Krueger
Ryan Lageman
Tessa Londre
Kyle Raker
Allyson Wells
Jason Wheeler
2005 Udall Scholar
Laura Sima
Palmetto Fellows Scholarship
Asma Baig
Michael Bechtold
Christa Campbell
Anne Ellefson
Brandon Floyd
Benjamin Garrett
Bradley Hocking
Melanie Hough
Ryan Lageman
Mary Jo Manuse
Perry McGriff
Kimberly Painter
Anand Pariyadath
Matthew Skiles
Elizabeth Sutton
Heather Taylor
Allyson Wells
Jason Wheeler
Jonathan Wooten
Kevin Yehl
South Carolina National Guard
Andrea Gooden
Jerome D. Odom Fellowship
Elizabeth Tucker
2005 Copenhaver Scholars
Heather Brooke
William Carroll
Christopher Cooper
William Pearl
Boyd Pritchard
Irina Puzdrjakova
Fundeberg/Copenhaver Scholar
Justin Jones
Murtiashaw/Copenhaver Scholar
Gagandeep Kaur
University Scholars
Asma Baig
Alison Bush
Christa Campbell
Travis Deason
Benjamin Garrett
Melanie Hough
Nathaniel Krueger
Ryan Lageman
Mary Jo Manuse
Kimberly Painter
Samantha Roberson
Daniel Stevenson
Demetria Strauch
Heather Taylor
Bryan Vasser
Allyson Wells
Kevin Yehl
The Outstanding Achievement
and Student Triumph Award
(TOAST): Jon Scaffidi, Timothy
Black, Jay Ratliff
Poster Competition Winners:
Brian Chiswell
Andrea Goforth
Robert Osborne
David Perkins
Gemini Industries Research
Grant: William Gemmill
Ph.D. and MS Graduates
2004–2005
2005 Graduate Student
Research Symposium
Guy F. Lipscomb Award:
Paula Colavita
IRIX Pharmaceuticals Award:
Nathaniel Greene
Oakwood Products Award:
Roshan Perera
Graduate Student Day 2005
Scholarly Posters Competition:
Linfeng Gou, Third Place
J.R. Durig Graduate Student
Travel Awards 2004–2005
Hannah Barnhill
Nathaniel Greene
Fang Xie
Valedictorian Scholars
Michael Bechtold
Anand Pariyadath
Jonathan Wooten
Cancer Research Travel Award
Winners 2004–2005
Leslie Lovelace
Roshan Perera
Graduate Organizations
Students for the Advancement
of Chemical Sciences (SACS)
2004–2005 Officers
Timothy Black, President
Garrison Reese, Vice President
Brandon Cash, Secretary
Jay Ratliff, Treasurer
Voridian Analytical Travel Award
Winners 2004–2005
Christopher Dockery
David Perkins
Luisa Profeta
Jie Qin
Graduate Fellowships
IRIX Fellowship
Jennifer McPhail
14
Spring 2005
Lisa Brodhacker
Jasmine Ervin
Lydia Gibson
Theppawut Israsena Na Ayudhya
Roger Rasberry
James Ruff
Other Awards
Graduate Student
Competitions
USC Employee Assistance
Scholarship
Valerie Kennedy
Bouknight Teaching Award
Fall 2004
Lydia Gibson
Jennifer McPhail
Craig Mooneyham
Roger Rasberry
Mitch Weiland
Ph.D. Graduates
August 2004
Geqing Chai
Jack Pender
Gregory Rushton
Radu Semeniuc
December 2004
John Berch
Anindya Dasgupta
Yuan Luo
Shaobin Miao
Alexander Nieuwland
Xiaoyou Xu
May 2005
Jinxin Gao
Jonathan Scaffidi
Roshan Perera
Jack Smith
MS Graduates
August 2004
William Burns
Ashley Reese
Frederick Parsons
December 2004
Kelly Hefner
Nanlin Li
Chunlian Shi
2004–2005 Donors
Friends of Chemistry
and Biochemistry
$500—Corporation
$150—Individual
$50—Retiree
3V, Inc.
Abbott Laboratories
Mr. Stanley C. Alford
Mr. William Andahazy
Mr. Steven Beckham
Dr. Elisabeth T. Bell Loncella
Mrs. Julia J. Belton
Dr. Rajiv John Berry
Dr. Ruta K. Bly and
Dr. Robert S. Bly
Dr. Anthony M. Boccanfuso
Borden Chemical, Inc.
Ms. Julia L. Bouknight
Dr. William E. Brewer
Dr. Patricia A. Brletic
Dr. William E. Bucy
The Honorable Mark W. Buyck Jr.
Central Carolina Community
Foundation
Coca-Cola Foundation, Inc.
Mr. William R. Cook Sr.
Dr. John H. Dawson
Dr. and Mrs. John J. Duffy
Dr. and Mrs. James R. Durig
Dr. Daniel G. Dyer
Eastman Chemical Company
Mr. William T. Fetner
Dr. Thomas J. Geyer
Dr. Benjamin M. Gimarc
Dr. Leon H. Ginsberg
Dr. and Mrs. William H. Green
Dr. and Mrs. Donald J. Greiner
Mr. and Mrs. Ronald J. Grey
Ms. Norah T. Grimball
Mr. R. Graham Harris
Dr. Barton K. Hawkins
Dr. Lee A. Henderson
Dr. Gregory L. Hillhouse
Hope Grey N.C.
Mr. John C. Houser
Dr. Beth A. Huggins and
Dr. Thomas G. Huggins Jr.
I.P. Research, Inc
IRIX Pharmaceuticals, Inc.
Mr. Michael H. Johnson
Mr. Theodore B. Johnson
Dr. Malathi K. Kistler and
Dr. W. Stephen Kistler Jr.
Dr. Gretchen E. Koehler and
Mr. John V. Skvoretz Jr.
Dr. Donald G. Kubler
Dr. T. Scott Little
Ms. Kathryn E. MacLeod
Dr. David M. Maryniak
Matrix Scientific
Mr. Rowland L. Matteson Jr.
Mr. William H. McCall Jr.
Mr. Ross S. McKenzie Sr.
Dr. and Mrs. Fred M. McLean
Mrs. Kelley R. Mintz
Dr. Robert F. Moates
Dr. Patricia G. Moody
Oakwood Products Incorporated
Dr. Jerome D. Odom
Para-Chem Southern, Inc.
Dr. Harris Pastides
Dr. Daniel L. Reger
Dr. Thomas C. Register
Mr. Edmond T. Richardson Jr.
Dr. and Mrs. Steven Riethmiller
Mrs. Virginia H. Rogers
Dr. Peter C. Sederberg
Dr. Donald W. Sink
Mr. Louis A. Silks III
Dr. Gordon B. Smith
Teleflex Foundation
The New York Times
Company Foundation
Dr. Suzanne R. Thorpe and
Dr. John W. Baynes
USC Business Partners Foundation
USC Development Foundation
USC Research Foundation
Dr. Gregory S. Welmaker
Dr. James N. Willis Jr.
Dr. Joann S. Wood
Mrs. Marian J. Woolsey
Dr. and Mrs. Ben W. Wright
Dr. John H. Yamamoto
Dr. Mary L. Zozulin and
Dr. Alexander J. Zozulin
Dr. Julia P. Baker
Dr. K.L. Ballington
Mr. Richard R. Barton
Dr. Ayse Batova
Mr. and Mrs. Vincent W. Batten
Dr. Janet C. Baxter
Ms. Syderis D. Burkett
Ms. Susan E. Butts
Ms. Ann C. Cameron
Dr. and Mrs. Roscoe O. Carter
Dr. John M. Casper
Mr. George Alexander Cherry
Dr. Yu-Chung Chou
Dr. Zissis Chroneos
Ms. Helga J. Cohen
Mr. William M. Coleman III
Dr. William E. Cotham
Dr. Frank O. Cox
Dr. James P. Deavor
Ms. Susanna B. DesJardien
Dr. John L. Edwards
Dr. Roger William Farmer
Dr. Skottowe B. Fishburne Jr.
Dr. Alan M. Gabrielli
Gartner
Dr. Dennis Jay Gerson
Mr. Rowland L. Girling
GlaxoSmithKline Foundation
Mrs. Sandra H. Greenwood
Mr. Harry L. Gregory Jr.
Dr. Walter Gunter
Dr. Tamela Hamilton and
Mr. Christopher Hamilton
Mrs. Marci Kunkle Harvey
Dr. and Mrs. Todd James Hizer
Dr. Janette Turner Hospital
Dr. Sarah J. Hudson and
Dr. Stephen Douglas Hudson
Mr. Derrick E. Huggins
Ms. Tammy P. Hyatt
IBM Corporation
Mr. Ray Dyer III
Ms. April Lavette Irby
Dr. Judith Iriarte-Gross
Dr. Robert D. Johnson
Dr. Michael Lee Junker
Dr. John M. Karriker
Dr. William Edward Kemnitzer
Mr. Jason Blair Knight
Mr. and Mrs. Jan Kochansky
Lt. Col. William. A. Krouse Jr.
Other Donors
Dr. Richard D. Adams
Alcoa Foundation
Alliant Techsystems
15
Dr. Marian M. Larisey and
Dr. W.H. Breazeale Jr.
Dr. John E. Mahaffey
Dr. Scott S. Mason
Dr. Ronald J. Mattson
Mr. J. Terrell May
Dr. Elaine S. Mayhall
Mega Concentrate, LLC
Mrs. Myra Beth Merrell Pryor
Dr. Anne C. Miller
Dr. Thomas F. Moore
Dr. Stephen L. Morgan
Dr. William A. Munroe
Dr. Alycen and Mr. Stephen Nigro
NCR Corporation
Dr. Sean O’Connor
Dr. James M. Overton
Dr. Chasta L. Parker
Dr. Kristen Sellers Pate
Dr. Karen L. Pompeo and
Dr. Michael Paul Pompeo
Dr. Matthew Przybyciel
Mr. Vitaly A. Rassolov
Mr. Douglas M. Reamer
Dr. James C. Rogers
Ms. Chrystel B. Rogers
Dr. Jamal J. Rossi
SBC Foundation
Dr. Harry E. Shealy Jr.
Mrs. Kathie K. Snyder
Dr. James M. Sodetz
Mrs. Sangeeta S. Sohoni
Dr. Everett Spell
Dr. Dale L. Stone
Dr. Zvi Szafran
Dr. Qun Tang
Ms. Julia Ann Thur
Dr. Marc E. Tischler
Dr. William H. Tolleson
Dr. Richard L. Veazey
Dr. Carrie Lynne Wagner and
Dr. Thomas Joseph Connick
Dr. Michael D. Walla
Dr. Aiying Wang
Waters Corporation
Mrs. Elizabeth L. Watkins
Dr. Ruilian Wu
Wyeth
Mr. Yong Zhang
Dr. Ming Zhao
left to right: Roger Sawyer, assistant dean of the
College of Arts and Sciences; Bill Floyd, Industrial
Advisory Board member; James Hendrix, Industrial
Advisory Board member and adjunct professor;
Daniel Reger, Carolina Distinguished Professor and
chair. Bill Floyd presents a donation to the Department of Chemistry and Biochemistry on behalf of the
Industrial Advisory Board. These funds will be used
to support CHEM 401, “A Chemistry Capstone Experience: Careers in Chemistry.” Donations were made
by Para-chem Southern, Borden Chemical, Inc., and
IRIX Pharmaceuticals Inc.
05485 University Publications 10/05
The University of South Carolina provides equal opportunity and affirmative action in education and employment for all qualified persons regardless of race, color, religion, sex, national origin, age, disability, sexual orientation, or veteran status.
NON PROFIT
ORGANIZATION
U.S. POSTAGE
Department of Chemistry and Biochemistry
Columbia, SC 29208
PAID
PERMIT #766
COLUMBIA, SC
16