Abbott Nutrition Abbott House Vanwall Business Park Vanwall Road Maidenhead Berkshire SL6 4XE Tel: +44 (0)1628 773355 Fax: +44 (0)1628 644510 www.abbottnutrition.co.uk September 2013 IMPORTANT PRODUCT UPDATE Reformulation of Nepro sip and tube feed to Nepro HP Dear Customer, We are writing to inform you of an important product update. Throughout October and November 2013, the current formulation of Nepro will be discontinued, and we are delighted to announce that a new formulation (Nepro HP) will be launching in its place. This new product has a number of important differences that you need to be aware of and it will require you to review and adjust your patients’ feeding regimens as appropriate, and inform the patient’s GP as necessary. These important changes are: The product name Nepro is changing to Nepro HP Protein content will increase to 8.1g per 100ml (from 7.0g per 100ml) Energy density will reduce slightly to 1.8kcal/ml (from 2.0kcal/ml) Addition of a new slow release carbohydrate blend Minor reformulation of the micronutrients Improved palatability1* Introduction of ‘easy to use’ 220ml recloseable plastic bottles2 Nepro 500ml Ready to hang (RTH) & 200ml tetrapak presentations Nepro HP 500ml Ready to hang (RTH) & new 220ml recloseable plastic bottle (RPB) presentations What has changed? Nepro will be discontinued, and a new formulation (Nepro HP) will be launching in its place. The HP stands for High Protein, and this is to signify the increased protein content in this new formulation. Protein: based on customer feedback, protein levels have been increased from 7.0g (Nepro) to 8.1g (Nepro HP) per 100ml, to meet the increased protein requirements of renal patients. Carbohydrate: a new slow release carbohydrate blend has been used, which may aid the control of blood glucose levels. Energy: the energy content has decreased slightly from 2.0kcal/ml to 1.8kcal/ml. Micronutrients: there have been multiple minor formulation changes. Palatability: based on research with renal patients, the palatability of Nepro HP is preferred overall to Nepro1*, which may aid compliance. Presentation: we are delighted to announce that the 200ml tetrapaks will be replaced by 220ml easy to use2 recloseable plastic bottles, in both vanilla and strawberry flavours. When will this transition happen? Current stocks of Nepro will be depleted during October and November 2013, and overlapping supplies of Nepro HP will become available to patients at the same time. We expect a period of 1-2 months where both products will be available in the market, and we will be working closely with wholesalers, pharmacies, and GPs to make sure this transition is as seamless as possible. What do I need to do? Please review the nutritional profiles of both Nepro and Nepro HP (see appendix) and adjust your patients’ feeding regimens as appropriate. Please inform the patient’s GP regarding the name change and any other change in prescription as necessary. If you wish to arrange a meeting, or to receive further information on Nepro HP, please do not hesitate to contact your local Abbott Nutrition representative, visit our website at www.abbottnutrition.co.uk or call our Freephone Nutrition Helpline on 0800 252882. 1. Data on file. Abbott Laboratories Ltd., 2012 (Palatability research). 2. Data on file. Abbott Laboratories Ltd., 2007 (Bottle ease of use). * Based on a comparison between Nepro vanilla flavour with Nepro HP vanilla flavour and Nepro HP strawberry flavour Nepro HP ordering information (from October 2013 onwards) Pack Size NHS (FP10) Price Nepro HP (Vanilla flavour) 15 x 500ml RTH £87.60 Nepro HP (Vanilla flavour) 30 x 220ml RPB Nepro HP (Strawberry flavour) 30 x 220ml RPB Pack Yours sincerely, Mark Roylance (BSc Hons) Business Development Manager List No PIP Code EAN Code S55101514 381-6436 5013158781832 £86.70 S55103014 381-6428 5013158781856 £86.70 S55203014 381-6410 5013158781870 Appendix: Comparison of Nepro and Nepro HP Nutrition Information Energy Protein Carbohydrate Fat Fibre of which FOS Vitamins Vitamin A (RE) Vitamin D Vitamin E (αTE) Vitamin C Thiamin (vitamin B1) Riboflavin (vitamin B2) Niacin (NE) Vitamin B6 Folacin (folic acid) Vitamin B12 Biotin Pantothenic acid Vitamin K Minerals Sodium Calcium Phosphorus (phosphate) Iron Magnesium Zinc Iodine Potassium Chloride Copper Manganese Selenium Chromium Molybdenum Taurine Carnitine Choline RXANI130269 Date of Preparation: August 2013 Units Per 100 ml New formulation (Nepro HP) kJ kcal g g g g g Current formulation (Nepro) 838 200 7.0 20.6 9.6 1.56 1.56 µg µg mg mg mg mg mg mg µg µg µg mg µg 63.4 0.21 3.4 10.5 0.26 0.29 3.4 0.86 105 0.65 8 1.7 9 95 1.2 3.4 10.5 0.42 0.5 3.4 0.5 60 0.85 9 1.6 9 84.5 (3.67) 137 (3.43) 69 (2.21) 1.9 21 (0.88) 2.2 16 106 (2.72) 101 (2.85) 210 0.55 8 0 0 16 16 63.5 70 (3.04) 106 (2.64) 72 (2.32) 1.9 21 (0.86) 1.9 16 106 (2.71) 84 (2.37) 210 0.21 7.4 4.5 8 16 26.5 63.5 mg (mmol) mg (mmol) mg (mmol) mg mg (mmol) mg µg mg (mmol) mg (mmol) µg mg µg µg µg mg mg mg 746 180 8.1 14.7 9.77 1.26 0.84