Co-ordination and response / sensitivity Motor Neurone Living organisms are able to respond to both internal and external stimuli. Co-ordination is the process whereby a living organism gives the correct response at the correct time to a particular stimulus. This allows the organism to adapt, to change, and increase their chance of survival. For example, when animals/humans get hungry, they go to find food – so that their chance of survival may increase. myelin sheath axon A stimulus is a change in the environment. This can be internal (e.g. hunger) or external (e.g. light, sound). Many stimuli are forms of energy and are detected by organs. These organs have receptors or receptor cells. A receptor detects a stimulus/change in the environment. It sets up an electrical current in the form of a nerve impulse. The electrical current will travel to a coordinating centre (e.g. brain/spinal cord), which would relay the impulse to an effector. nerve fibre direction of impulse motor nerve endings in nerve muscle Effectors are either muscles or glands. stimulus (change in environment) Synapse (gap) nucleus receptor direction of impulse branches of one fibre near cell body of next nerve cell nerve fibre co-ordinating centre effector response cell body Co-ordination is achieved by: 1. 2. the nervous system the endocrine system The Nervous system Receptors change particular types of energy into a nerve impulse. Receptors are transducers (i.e. they change energy from one form to another). For example, the eyes, ears, nose, tongue and skin – all our sense – are receptors. In order to make it an efficient communication system, the messages must travel rapidly and directly. The general structure of the nervous system consists of: 1. Central nervous system (C.N.S.) - brain and spinal cord 2. Peripheral nervous system (P.N.S.) - paired nerves arising form spinal cord 3. Autonomic nervous system (A.N.S.) - the part of the nervous system that maintains a constant internal environment (e.g. heartbeat) The basic unit of the nervous system: the neurone – nerve cell 1. Sensory neurone transmits a nerve impulse from the receptor cell to the central nervous system 2. Motor neurone transmits nerve impulse from central nervous system to effector 3. Relay/link/intermediate neurone carries nerve impulses from a sensory neurone to a motor neurone All of these transmit electrical impulses. They are found in different parts of the nervous system. Their structure varies. Sensory neurone Motor neurone Cell body Side of axon At end of axon Cell body In white matter of spinal cord (outer part) In grey part of spinal cord (central) axon axon Cell body cell body cell body Nerve cells are up to 1 metre long and are very thin (about 0.0005 mm in diameter). This allows for less diffusion and so a more rapid transmission of the impulse. The nerve impulses travel at approximately 100 metres per second! Axon relays nerve impulses over long distances. They are surrounded by a myelin sheath. Myelin sheath insulates the neurone so that there is little/no lateral transmission. Node of Ranvier speeds up the nerve impulses as they jump from one neurone to another. This is where electrical and chemical changes take place. Cell body in a motor neurone, this is where the impulse stars from Dendrites these are thin, cytoplasmic extensions by which nerve impulses are carried from one axon to effectors or the cell bodies of other neurones. Motor end plate this is where the impulses end (when going to muscle) Synapse At the end of each neurone there is a gap (there is no physical connection between one neurone and the next) between it and the next nerve cell or effector. This gap is called the “synapse”. The dendrites on one neurone do not directly touch the dendrites on the next neurone. Transmission across synapse ACH (acetylcholine) is the transmitter substance/chemical this is released from what is called the “synaptic knob” it is released into the synaptic gap it diffuses across the synapse in one direction it then combines with receptor sites on the “post synaptic membrane” this makes the membrane permeable to Na+ ions (causes depolarisation) the process is terminated by an enzyme: acetylcholine esterase N.B.: There is no physical connection between one neurone and the next. Nerve impulses are transmitted by chemical diffusion to cause de-polarisation in the next neurone (i.e. to make the next neurone send the same impulse). What is the nerve impulse? The nerve impulse is the electro-chemical change in the axon. When Na+ goes in, K+ immediately leaves. This causes a disturbance further along. To restore this to normal, there is a pump. + + Na K axon Nerve A nerve is a “collection (or bundle) of nerve fibres bound by connecting tissue”. Nerves may be mixed (i.e. have sensory and motor neurones) An outline of the “reflex arc”: dorsal root ganglion receptor detecting stimulus cell body synapse sensory neurone white matter cell body relay neurone grey matter motor neurone effect created in muscle or gland Notice that all synapses are in the grey matter. Reflex action Reflex actions do not require the brain for its initiation. It is voluntary (i.e. unconsciously done). However, it can be overridden by the brain and conscious thought. Definition: “ Rapid, automatic response by an organ / system of organs in response to a stimulus which does not require the brain for its initiation. You must know: the reflex arc – including what each part is the definition of a reflex action how nerve impulses are transmitted across the synapse ” Reflex centres There are two reflex centres: 1. Brain The medulla oblongata. This controls the facial expressions such as blinking, dilation of the pupil, yawning (yes, it is a reflex – so tell that to a teacher which blames you for yawning...it is automatic!) and sneezing. The medulla also controls reflexes to do with homeostasis (i.e. reflexes which are required to keep everything in the same state) e.g. breathing, heart rate, peristalsis and blood pressure. 2. Spinal cord This redirects the sensory impulses from the sensory neurone directly to the motor neurones via reflectors. This is for bodily reflexes such as knee jerks and what happens when you place your hand on a hot plate. There are three types of response to a stimulus: Type of response What it is Control Involuntary cannot be consciously controlled medulla / spinal cord Voluntary result of a conscious decision brain – e.g. action of kicking a ball Conditioned response association of two unrelated stimuli story of dog...see below! Example of controlled response Stretch receptors in the muscle inform the brain of how relaxed/contracted the muscle is. A high degree of control is needed when two or more muscles are working in antagonistic harmony. Nerve fibres in the stretch receptors of the muscle send nerve impulses / information to the spinal cord to indicate the degree to which the muscle is being stretched. This is then relayed to the brain which sends an impulse telling the muscle to contract/relax. Example of conditioned response There once was a dog. The person who owned the dog always rang a bell when he/she wanted to give the dog food. At first, the dog did not produce saliva when it heard the food, but it salivated (i.e. produce saliva) when it saw the food. After a while, it began to salivate when it heard the bell and saw the food. Then, it salivated when the bell was rung without any food being there. This is a conditioned response. The dog thought that there would be food when the bell rang and so it started to prepare itself by producing saliva.