Mezei Zsuzsa Lívia An Introduction to Basic Medical English Terminology 2 Coursebook for Students of Medicine Lektorálta: Krasznai Mónika A segédanyagot készítették: Szabóné Enyedi Gabriella, Papp Eszter, John Graham, Farkas János, Hajdu Zita, Dr. Nyilas Istvánné Dr. Laczkóné Rácz Edit, Louis J. Mattia, Major Judit, George Seel TÁMOP-4.1.2.D-12/1/KONV-2012-0008 Debrecen 2014 1 CONTENTS UNIT 1. DIGESTIVE SYSTEM I. (DIGESTIVE PROCESS, ORAL CAVITY, STOMACH, DISEASES OF THE STOMACH) ................................................................................................................................... 7 1.1 UNDERSTANDING HOW THE DIGESTIVE SYSTEM WORKS...................................................... 8 1.1.1 Introduction to the digestive tract (L)..................................................................................... 8 1.1.2 Overview of the digestive system (V) ..................................................................................... 8 1.1.3 The digestive process (R) ...................................................................................................... 10 1.1.4 Speaking about the digestive process (S) ............................................................................. 11 1.1.5 Digestive health (W) ............................................................................................................. 12 1.2 THE ORAL CAVITY .............................................................................................................. 13 1.2.1 Parts of the oral cavity (V) .................................................................................................... 13 1.2.2 The oral cavity: overview (R) ................................................................................................ 14 1.2.3 Permanent teeth (R) ............................................................................................................. 15 1.2.4 Tooth anatomy (V)................................................................................................................ 16 1.2.5 Oral health (V) ...................................................................................................................... 17 1.2.6 Dental care (S) ...................................................................................................................... 18 1.3 THE STOMACH .................................................................................................................. 18 1.3.1 Stomach - Quiz (R) ................................................................................................................ 18 1.3.2 Stomach Anatomy and Histology (R) .................................................................................... 19 1.3.3 Oral summary of the stomach (S) ......................................................................................... 22 1.3.4 Latin word roots (V) .............................................................................................................. 23 1.4 DISEASES OF THE STOMACH .............................................................................................. 23 1.4.1 Heartburn (R) ........................................................................................................................ 23 1.4.2 Foods to eat and avoid for heartburn (V) ............................................................................. 25 1.4.3. Student-patient communication (S) .................................................................................... 26 1.4.4 Other diseases of the stomach (R) ........................................................................................ 27 1.4.5 Answering patient’s email (W) ............................................................................................. 29 1.4.6. Endoscopy (L) ....................................................................................................................... 30 1.4.7 Explaining endoscopy to the patient (S) ............................................................................... 30 UNIT 2. DIGESTIVE SYSTEM II. (SMALL AND LARGE INTESTINES, LIVER) ......................................... 31 2.1 SMALL AND LARGE INTESTINES.......................................................................................... 32 2.1.1 Small Intestine (R) ................................................................................................................. 32 2.1.2 Large Intestine (R) ................................................................................................................ 34 2 2.1.3 Appendix and appendicitis (L)............................................................................................... 35 2.1.4 Asking questions about the large intestine (W) ................................................................... 36 2.1.5 Important vocabulary of the small and large intestines (V) ................................................. 37 2.2 DISEASES OF THE SMALL AND LARGE INTESTINES ............................................................... 38 2.2.1 Collecting ideas to food poisoning (V) .................................................................................. 38 2.2.2 FAQs about food poisoning (S) ............................................................................................. 38 2.2.3 Food poisoning facts (R) ....................................................................................................... 39 2.2.4 Doctor-patient conversation (S) ........................................................................................... 40 2.2.5 Diarrhoea (L) ......................................................................................................................... 40 2.2.6 Other common gastrointestinal diseases (R)........................................................................ 41 2.2.7 Doctor-patient conversations (S) .......................................................................................... 42 2.2.8 Most common gastrointestinal diseases: an essay (W) ....................................................... 43 2.3 THE LIVER ......................................................................................................................... 43 2.3.1 FAQs about the liver (S) ........................................................................................................ 43 2.3.2 Anatomy of the liver (V)........................................................................................................ 44 2.3.3 Functions of the liver (L) ....................................................................................................... 45 2.3.4 An interview about the diseases of the liver (W) .................................................................. 46 2.3.5 Facts about the liver (R)........................................................................................................ 47 2.3.6 Talking about the liver (S) ..................................................................................................... 48 2.5 VOCABULARY .................................................................................................................... 49 UNIT 3. NERVOUS SYSTEM .......................................................................................................... 52 3.1 THE CENTRAL NERVOUS SYSTEM ....................................................................................... 53 3.1.1 Brain Quiz (R) ........................................................................................................................ 53 3.1.2 Brain Anatomy (R) ................................................................................................................ 53 3.1.3 Important vocabulary of the CNS (V).................................................................................... 55 3.1.4 Basic structures of the brain (S) ............................................................................................ 56 3.1.5 Brain Anatomy Diagram (R) ................................................................................................. 56 3.1.6 Lobes of the brain (W) .......................................................................................................... 57 3.2 CRANIAL NERVES............................................................................................................... 58 3.2.1 Cranial Nerve Song (L) .......................................................................................................... 58 3.2.2 List of the cranial nerves (R) ................................................................................................. 59 3.2.3 Scatter (V) ............................................................................................................................. 61 3.3 SPINAL NERVES ................................................................................................................. 62 3.3.1 Revision (S) ........................................................................................................................... 62 3 3.3.2 Spinal nerves (R) ................................................................................................................... 62 3.3.3 Spinal Nerves - oral summary (S) .......................................................................................... 64 3.3.4 Coverings & spaces (V) ......................................................................................................... 64 3.4 COMMON DISEASES OF THE CENTRAL NERVOUS SYSTEM................................................... 65 3.4.1 FAQS (S) ................................................................................................................................ 65 3.4.2 Neurological diseases (R)...................................................................................................... 65 3.4.3 Talking about common neurological diseases (S) ................................................................ 69 3.4.4 Seizure first Aid (W) .............................................................................................................. 70 3.5 OLD AGE AND ALZHEIMER’S DISEASE ................................................................................. 73 3.5.1 Brainstorming – Old Age (V) ................................................................................................. 73 3.5.2 Caring for the elderly (S) ....................................................................................................... 73 3.5.3 Difficulties of the elderly (W) ................................................................................................ 74 3.5.4 Alzheimer’s disease facts (R) ................................................................................................ 75 3.5.5 Stages of Alzheimer’s (L)....................................................................................................... 76 3.5.6 Doctor-patient conversation (S) ........................................................................................... 77 3.6 THE PERIPHERAL NERVOUS SYSTEM .................................................................................. 78 3.6.1 The peripheral nervous system – Key points (V) ................................................................... 78 3.6.2 The neuron (R) ...................................................................................................................... 79 3.6.3 Parts of the PNS (S) ............................................................................................................... 81 3.7 MENTAL DISEASES............................................................................................................. 81 3.7.1 What is mental illness? (R) ................................................................................................... 81 3.7.2 Symptoms (V) ....................................................................................................................... 83 3.7.3 Common mental illnesses (R) ............................................................................................... 84 3.7.4 Tourette syndrome (R) .......................................................................................................... 86 3.7.5 List of tics (V) ........................................................................................................................ 87 3.7.6 Seasonal Affective Disorder (L) ............................................................................................. 87 3.7.7 Stigma of Mental Illnesses (S)............................................................................................... 88 3.8 VOCABULARY .................................................................................................................... 90 UNIT 4. RESPIRATORY SYSTEM .................................................................................................... 93 4.1 ANATOMY OF THE RESPIRATORY SYSTEM .......................................................................... 94 4.1.1 Introduction to the Respiratory System (L) ........................................................................... 94 4.1.2 Organs of the respiratory system (R).................................................................................... 95 4.1.3 Summary of the Respiratory System (W) ............................................................................. 98 4.1.4 Medical terms vs. common English names about the respiratory system (V)...................... 99 4 4.1.5 Identifying and speaking about the structures of the respiratory system (S) .................... 100 4.2 MUSCLES OF RESPIRATION, PHYSIOLOGY OF THE RESPIRATORY SYSTEM ...........................101 4.2.1 Respiration (R) .................................................................................................................... 101 4.2.2 Health effects of smoking (S) .............................................................................................. 104 4.2.3 Decreasing smoking rates (W)............................................................................................ 105 4.2.4 Types of cough (S) ............................................................................................................... 105 4.3 DISEASES OF THE RESPIRATORY SYSTEM ...........................................................................106 4.3.1 Lung cancer (R) ................................................................................................................... 106 4.3.2 COPD (V) ............................................................................................................................. 107 4.3.3 Chronic Obstructive Pulmonary Disease causes (L) ............................................................ 108 4.3.4 COPD Quiz (R) ..................................................................................................................... 109 4.3.5 Doctor- Patient conversation (S) ........................................................................................ 110 4.4 OTHER LUNG CONDITIONS AND ASTHMA .........................................................................110 4.4.1 Other lung conditions (R) .................................................................................................... 110 4.4.2 Asthma (L)........................................................................................................................... 113 4.4.3 Doctor-Patient conversation (S) ......................................................................................... 114 4.5 VOCABULARY ...................................................................................................................115 UNIT 5. THE IMMUNE SYSTEM ...................................................................................................117 5.1 OVERVIEW OF THE IMMUNE SYSTEM ...............................................................................118 5.1.1 Brainstorming – Immune System (V) .................................................................................. 118 5.1.2 Basic terms (V) .................................................................................................................... 118 5.1.3 Function and location of the Immune System (R)............................................................... 119 5.1.4 Immune Response to Bacteria (L) ....................................................................................... 121 5.1.5 Immune System Boosters and Busters (S) .......................................................................... 122 5.2.1 Getting to know about autoimmune diseases (R) .............................................................. 123 5.2.2 Multiple sclerosis (L) ........................................................................................................... 125 5.2.3 Living with MS (S) ............................................................................................................... 128 5.2.4 Coping with MS diagnosis (L).............................................................................................. 129 5.2.5 Giving advice (W)................................................................................................................ 130 5.2.6 Talking about MS (S)........................................................................................................... 131 5.3. ORGAN TRANSPLANTATION ............................................................................................131 5.3.1 Background Vocabulary (V) ................................................................................................ 131 5.3.2 Organ Transplantation - Frequently Asked Questions (S) .................................................. 132 5.3.3 The Immune System and Organ Transplant (R).................................................................. 132 5 5.4 FOOD ALLERGY.................................................................................................................134 5.4.1 Major allergenic foods (V) .................................................................................................. 134 5.4.2 Understanding food allergy (L) ........................................................................................... 135 5.4.3. Food Allergy – Everything you need to know (R) ............................................................... 136 5.4.4 Type-1 Hypersensitivity: IgE mediated food allergy (L) ...................................................... 138 5.4.5. Communicating with the patient (S).................................................................................. 139 5.4.6 Celiac disease (R) ................................................................................................................ 141 5.4.7 Celiac disease: giving advice (S) ......................................................................................... 142 5.5. AIDS ...............................................................................................................................143 5.5.1 FAQ (S) ................................................................................................................................ 143 5.5.2 Frequent words in connection with AIDS (V) ...................................................................... 144 5.5.3 Everything you need to know about AIDS (L) ..................................................................... 144 5.5.4 Talking about AIDS (S) ........................................................................................................ 145 5.6 VOCABULARY ...................................................................................................................146 L = listening activity; R = reading activity; S = speaking activity; W = writing activity; V = vocabulary development activity 6 UNIT 1. DIGESTIVE SYSTEM I. (DIGESTIVE PROCESS, ORAL CAVITY, STOMACH, DISEASES OF THE STOMACH) Aims of the Unit In this unit you will learn about: the digestive process, the oral cavity, the stomach and diseases of the stomach. 7 1.1 UNDERSTANDING HOW THE DIGESTIVE SYSTEM WORKS LISTENING 1.1.1 Introduction to the digestive tract (L) 1. Listen to the recording about digestion of food and tick (√) the words you hear in the text. Source: http://www.youtube.com/watch?v=44sf_AL8pfw digest ______ mouth______ teeth ______ mince______ gland ______ esophagus______ sphincter muscle______ nutrients______ ear ______ liver______ pancreas______ large intestine______ stomach______ chyme______ bones ______ swallow______ grind ______ mastication______ saliva______ small intestine______ valve______ 2. Listen again and answer the questions below. 1) What are the life giving nutrients for the body? 2) What is the job of the teeth? 3) What is mastication? 4) What is the function of saliva? 5) What organ does food passes through from the mouth into the stomach? 6) What can be found at the lower end of the esophagus? 7) What is the function of the sphincter muscle? 8) What is food texture like once it is ready to leave the stomach? What is it called? VOCABULARY DEVELOPMENT 1.1.2 Overview of the digestive system (V) 1. Match the words in the box with the definitions. mouth rectum anus appendix stomach pancreas esophagus gall bladder small intestine liver large intestine 8 _________________: the opening at the end of the digestive system from which feces exit the body. _________________: a small sac located near the start of the large intestine. _________________: the long tube between the mouth and the stomach. It uses rhythmic muscle movements (called peristalsis) to force food from the throat into the stomach. _________________: a small, sac-like organ located by the duodenum. It stores and releases bile (a digestive chemical which is produced in the liver) into the small intestine. _________________: the long, wide tube that food goes through after it goes through the small intestine. _________________: a large organ located above and in front of the stomach. It filters toxins from the blood, and makes bile (which breaks down fats) and some blood proteins. _________________: the first part of the digestive system, where food enters the body. Breaking down the food by chewing and salivary enzymes are the beginning of the digestive process. _________________: an enzyme-producing gland located below the stomach and above the intestines. Enzymes produced here help in the digestion of carbohydrates, fats and proteins in the small intestine. _________________: the lower part of the large intestine, where feces are stored before they are excreted from the body. _________________: the long, thin winding tube that food goes through after it leaves the stomach. _________________: a sack-like, muscular organ that is attached to the esophagus. When food enters this organ, it is churned in an acid bath. http://www.enchantedlearning.com/subjects/anatomy/digestive/labeleasy/ 3. Label the diagram with the words from the box above. http://www.enchantedlearning.com/subjects/anatomy/digestive/labeleasy/ 9 READING 1.1.3 The digestive process (R) 1. Read the text and answer the questions below! The digestive process The start of the process - the mouth: The digestive process begins in the mouth. Food is partly broken down by the process of chewing and by the chemical action of salivary enzymes (these enzymes are produced by the salivary glands and break down starches into smaller molecules). On the way to the stomach: the esophagus - After being chewed and swallowed, the food enters the esophagus. The esophagus is a long tube that runs from the mouth to the stomach. It uses rhythmic, wave-like muscle movements (called peristalsis) to force food from the throat into the stomach. This muscle movement gives us the ability to eat or drink even when we're upside-down. In the stomach - The stomach is a large, sack-like organ that churns the food and bathes it in a very strong acid (gastric acid). Food in the stomach that is partly digested and mixed with stomach acids is called chyme. In the small intestine - After being in the stomach, food enters the duodenum, the first part of the small intestine. It then enters the jejunum and then the ileum (the final part of the small intestine). In the small intestine, bile (produced in the liver and stored in the gall bladder), pancreatic enzymes, and other digestive enzymes produced by the inner wall of the small intestine help in the breakdown of food. In the large intestine - After passing through the small intestine, food passes into the large intestine. In the large intestine, some of the water and electrolytes (chemicals like sodium) are removed from the food. Many microbes (bacteria like Bacteroides, Lactobacillus acidophilus, Escherichia coli, and Klebsiella) in the large intestine help in the digestion process. The first part of the large intestine is called the cecum (the appendix is connected to the cecum). Food then travels upward in the ascending colon. The food travels across the abdomen in the transverse colon, goes back down the other side of the body in the descending colon, and then through the sigmoid colon. The end of the process - Solid waste is then stored in the rectum until it is excreted via the anus. 1) Where does the digestive process start? __________________________________________ 2) What are salivary enzymes? ____________________________________________________ 3) How is food forced from the throat into the stomach? _______________________________ 4) What is chyme? ______________________________________________________________ 10 5) What are the parts of the small intestine? _________________________________________ 6) What are produced in the small intestine? _________________________________________ 7) What are removed from food in the large intestine? ________________________________ 8) What are the parts of the large intestine? _________________________________________ 9) How does the process end? ____________________________________________________ http://www.enchantedlearning.com/subjects/anatomy/digestive/ http://www.bing.com/images/search?q=the+digestive+process&FORM=HDRSC2#view=detail&id=A1B4CAFEC5AF98DE96BB7175CD1A973CFDADE8A0&selecte dIndex=1 SPEAKING 1.1.4 Speaking about the digestive process (S) Write down the most important information from the text above then with the help of your notes speak about the digestive process. Mouth Esophagus Stomach Small intestine Large intestine Rectum 11 http://www.ellies-whole-grains.com/human-digestive-system.html#axzz37BNYG6YF WRITING 1.1.5 Digestive health (W) You read the following article in a magazine. Write an essay (180-200 words) about how to improve your digestive health. How to improve your digestive health Many people suffer from digestive issues, such as constipation, diarrhea, irritable bowel syndrome, bloating, nausea, intolerance and celiac disease. Some of these conditions can be avoided by following a healthy, doctorrecommended diet. If you have digestive issues, you may consider slowly changing your eating habits. http://www.wikihow.com/Improve-Your-Digestive-Health 12 In your essay write about: foods that a healthy diet should contain (probiotics, fibers etc.) foods and unhealthy habits to avoid the amount of food eaten per meals tips to lose weight, importance of exercise importance of proceeding gradually in changing diet 1.2 THE ORAL CAVITY VOCABULARY DEVELOPMENT 1.2.1 Parts of the oral cavity (V) Match the words (a-f) with the definitions (1-6). a a) b) c) d) e) f) 1. 2. 3. 4. 5. b c d e f oral cavity vestibule hard palate soft palate uvula cheeks The fleshy part of either side of the face below the eye and between the nose and ear which form the lateral walls of the oral (and buccal) cavity The relatively hard, vaulted anterior portion of the palate forming the anterior portion of the roof of the mouth The small, conical, fleshy mass of mucosal tissue suspended from the center of the soft palate; it assists in completing the closure of the nasal cavity by the soft palate during swallowing or sucking The first portion of the gastrointestinal tract, the opening through which food is taken in and vocalizations emerge, it is bounded by the lips, cheeks, palate, and tongue, and ends where it merges with the oropharynx The movable fold, consisting of skeletal muscular fibers enclosed in a mucous membrane, 13 6. which is suspended from the rear of the hard palate and closes off the nasal cavity from the oral cavity during swallowing or sucking; the uvula depends from it In general, a cavity, chamber, or channel which leads to or is an entrance to another cavity; in the oral cavity, it is the medial continuation of the buccal cavity, located between the jaws and teeth and the labia http://apbrwww5.apsu.edu/thompsonj/Anatomy%20&%20Physiology/2020/2020%20Exam%20Reviews/Exam %203/CH23%20Oral%20Cavity%20I%20-%20Walls.htmREADING READING 1.2.2 The oral cavity: overview (R) 1. Complete the text with the missing words. The first letter is given in each word. The oral cavity represents the first part of the digestive tube. Its primary function is to serve as the entrance of the 1. a________________ tract and to initiate the digestive process by salivation and propulsion of the alimentary bolus into the 2. p________________. It also serves as a secondary respiratory 3. c________________, a site of sound modification for the production of speech and a chemosensory organ. The mobility of the 4. l________________ is also critical to speech production, whistling, singing, the playing of wind and brass musical instruments, and human behavioral communication (e.g. kissing, smiling, pouting). The oral cavity is oval shaped and is separated into the oral vestibule and the oral cavity. It is bound by the lips anteriorly, the 5. c________________ laterally, the floor of the mouth inferiorly, the oropharynx posteriorly, and the 6. p________________ superiorly. The oropharynx begins superiorly at the 7. j_______________ between the hard palate and the soft palate, and inferiorly behind the circumvallate papillae of the 14 tongue. The oral cavity includes the lips, gingivae, retromolar trigone, teeth, hard palate, cheek mucosa, mobile tongue, and floor of the mouth. The major salivary glands are in close relation with oral cavity structures, although they are not part of the oral cavity. The 8. t_______________ is part of the oral cavity. The palatine tonsils, soft palate, tongue base, and posterior pharyngeal walls are part of the oropharynx; the oropharynx is not part of the oral cavity. http://emedicine.medscape.com/article/1899122-overview 2. Answer the following questions. 1) What are the functions of the oral cavity? 2) Why is the mobility of the lips vital? 3) What shape is the oral cavity? 4) What are the two parts of the oral cavity? 5) What is the oral cavity bound by anteriorly, posteriorly, laterally, inferiorly and superiorly? READING 1.2.3 Permanent teeth (R) 1. Read the definitions then label the permanent teeth on the diagram. Humans have two sets of teeth, the baby teeth (also called the primary teeth) and the permanent teeth. Children have 20 primary teeth; they are replaced by the permanent teeth by about age 13. Adults have 32 permanent teeth. canine (also called cuspid) - the pointy tooth located between the incisors and the premolars. A canine tooth has 1 root. Adults have 4 canine teeth (2 in the top jaw and 2 in the bottom jaw). Canine means, "of or like a dog." incisors - the front teeth, used for cutting food. An incisor has 1 root. Adults have 8 incisors (4 in the top jaw and 4 in the bottom jaw). premolars (also called bicuspids) - the teeth located between the canine and the molars. A premolar tooth has 1 root. Bicuspids have two points (cusps) at the top. Adults have 8 premolars (4 in the top jaw and 4 in the bottom jaw). molars - the relatively flat teeth located towards the back of the mouth, used for grinding food. Molars in the top jaw have 3 roots; molars in the lower jaw have 2 roots. Adults have 12 molars (6 in the top jaw and 6 in the bottom jaw). 15 http://www.enchantedlearning.com/subjects/anatomy/teeth/labelteeth/ VOCABULARY DEVELOPMENT 1.2.4 Tooth anatomy (V) Do the following tooth quiz with the help of the picture and definitions. Cementum - a layer of tough, yellowish, bone-like tissue that covers the root of a tooth. It helps hold the tooth in the socket. The cementum contains the periodontal membrane. Crown - the visible part of a tooth. Dentin - the hard but porous tissue located under both the enamel and cementum of the tooth. Dentin is harder than bone. Enamel - the tough, shiny, white outer surface of the tooth. Gums - the soft tissue that surrounds the base of the teeth. Nerves - nerves transmit signals (conveying messages like hot, cold, or pain) to and from the brain. Periodontal membrane/ligament - the fleshy tissue between tooth and the tooth socket; it holds the tooth in place. The fibers of the periodontal membrane are embedded within the cementum. Pulp - the soft center of the tooth. The pulp contains blood vessels and nerves; it nourishes the dentin. Root - the anchor of a tooth that extends into the jawbone. The number of roots ranges from one to four. 16 1) The visible part of the tooth is called the ____________________________ 2) What is the name of the hard, white, outer layer of a tooth? __________________________ 3) What is the name of the tissue just below this outer layer? ____________________________ 4) The bottom part of the tooth that anchors it in the gums and jawbone is called the ____________________________ 5) What is the name of the soft center of a tooth? ____________________________ 6) What does this soft area contain? ____________________________ 7) What is the name of the soft tissue that surrounds the base of teeth? ___________________ 8) What is the name of the tough outer layer of the roots? ____________________________ http://www.enchantedlearning.com/subjects/anatomy/teeth/toothanatomy.shtml http://www.enchantedlearning.com/subjects/anatomy/teeth/toothquiz.shtml VOCABULARY DEVELOPMENT 1.2.5 Oral health (V) 1. Collect words and expressions that come to your mind concerning ‘oral health’. Oral Health 2. Name the following items in English. a._______________ e._______________ b._______________ c._______________ f._______________ d._______________ g._______________ h._______________ 17 SPEAKING 1.2.6 Dental care (S) 1. With a partner, discuss the following questions. 1) 2) 3) 4) 5) 6) How should you take good care of your teeth according to dentists? How often is it advised to visit a dentist? Why are regular checkups important? What kind of problems can a dentist detect? How does a dentist treat you if tooth decay is detected? What ensures the treatment is not painful? 2. Speak about the following topics in your own words with the help of the given prompts. role of the teeth dangers of bad teeth how to keep your teeth clean problems treated by dentists how is a tooth decay treated 1.3 THE STOMACH READING 1.3.1 Stomach - Quiz (R) 1. Do the quiz below! Decide if the following statements are True (write T) or False (write F). 1) 2) 3) 4) 5) 6) 7) 8) Absorption doesn’t get place in the abdomen. _____ You cannot contract the stomach. _____ Stomach dimension relay to body size/weight. ______ Exercise cannot modify the dimension of our stomach. _____ It doesn’t kill bacteria. ______ It is a muscular organ. _____ When you blush, the lining of your stomach also turns red! _____ Your stomach produces a new layer of mucous every two weeks. _____ 18 9) Without stomach life is simply not possible. _____ 10) Stomach acid is corrosive. _____ http://whatthafact.com/interesting-facts-about-stomach/ http://www.softschools.com/facts/human_body/the_stomach_facts/341/ http://science-facts.top5.com/5-fascinating,-terrifying-things-about-the-human-stomach/ READING 1.3.2 Stomach Anatomy and Histology (R) 1. Match the words (1-5) with the definitions (A-E). 1) 2) 3) 4) 5) 6) A B C D E F _____ sphincter _____ ruga(e) _____ pyloric _____ pepsinogen _____ secrete _____ gastrin a zymogen secreted by the chief cells of the gastric glands and converted into pepsin in the presence of gastric acid or of pepsin itself A hormone secreted in the stomach that is involved in the production of gastric acid. Overproduction of gastric acid contributes to peptic ulcer formation. a ridge or fold, such as the rugae of the stomach, which are large folds in the mucous membrane of that organ A ringlike muscle that normally maintains constriction of a body passage or orifice and that relaxes as required by normal physiological functioning. pertaining to the pylorus or to the pyloric part of the stomach to produce a liquid substance 2. What do the following words refer to? Explain them in your own words. 1. fluidisation 2. secretion 3. gland 4. to break up 3. Read the text and answer the questions below. 19 The stomach is a muscular 'j'-shaped organ located on the left side of the upper abdomen. The stomach receives food from the esophagus. As food reaches the end of the esophagus, it enters the stomach through a muscular valve called the lower esophageal sphincter. The stomach secretes acid and enzymes that digest food. Ridges of muscle tissue called rugae line the stomach. The stomach muscles contract periodically, churning food to enhance digestion. The pyloric sphincter is a muscular valve that opens to allow food to pass from the stomach to the small intestine. The stomach has four regions- the cardia, fundus, body and pylorus. Each region performs different functions; the fundus collects digestive gases, the body secretes pepsinogen and hydrochloric acid, and the pylorus is responsible for mucus, gastrin and pepsinogen secretion. The stomach has five major functions; Temporary food storage Control the rate at which food enters the duodenum Acid secretion and antibacterial action Fluidisation of stomach contents Preliminary digestion with pepsin, lipases etc. The Stomach – Histology G- mucosa containing glandular tissue; different areas of the stomach contain different types of cells which secrete compounds to aid digestion. The main types involved are: o parietal cells which secrete hydrochloric acid o chief cells which secrete pepsin o enteroendocrine cells which secrete regulatory hormones. MM- muscularis mucosae SM- submucosa The stomach contains three layers of involuntary smooth muscle which aid digestion by physically breaking up the food particles; o o o OM- inner oblique muscle CM- circular muscle LM- outer longitudional muscle 20 http://www.le.ac.uk/pa/teach/va/anatomy/case6/frmst6.html 1) What shape is the stomach? 2) What are the regions of the stomach? 3) What are the functions of the different regions of the stomach? 4) What are the functions of the stomach? 5) Where does food enter the stomach? 6) Where does food leave the stomach? 7) What kind of cells does the stomach contain to aid digestion? 8) What kind of muscles does the stomach contain to aid digestion? 4. Label the diagram with the words from the box. Pyloric Region of the stomach Duodenum of the small intestine Rugae Cardiac region of the stomach Pyloric Sphincter Valve Fundus Cardiac Sphincter Valve Body of the stomach Esophagus 21 http://anatomycorner.com/main/anatomy-topics/digestive-system/stomach-label/ SPEAKING 1.3.3 Oral summary of the stomach (S) In pairs, speak about the stomach. The prompts may help you. Take turns. shape of the stomach regions of the stomach functions of the different regions of the stomach functions of the stomach cells of the stomach muscles that aid digestion 22 VOCABULARY DEVELOPMENT 1.3.4 Latin word roots (V) Match the words in A to the words in B and write the solutions into the table below. A B 1 rrhagia a excessive flow of gastric secretion 2 pept b inflammation of the stomach and intestines 3 Gastrorrhea c digestion 4 gastr/o d inflammation of the stomach 5 enter e inflammation 6 gastroenteritis f bleeding 7 -ic g stomach 8 -rrhea h abnormal flow 9 gastritis i pertaining to 10 -itis j small intestine 1 2 3 4 5 6 7 8 9 10 1.4 DISEASES OF THE STOMACH READING 1.4.1 Heartburn (R) 1. Do the following quiz on ‘Heartburn’, write (T) for true or (F) for false or choose the correct answer. Then read the text below and check your answers. 1. Heartburn hurts your heart. _____ 2. Chewing gum can help heartburn. _____ 3. Using a lot of pillows when you sleep can make heartburn better. _____ 23 4. If you are overweight, the best way to stop heartburn is to drop some pounds. _____ 5. You are most likely to have heartburn when you: a) Wear tight pants b) Lie down after a meal c) Both the above 6. Taking antacids too much can cause: a) leg cramps b) constipation c) fatigue 7. How long should you wait between dinner and going to bed? a) 1 to 2 hours b) 2 to 3 hours c) 3 to 4 hours 8. Can you have GERD (gastroesophageal reflux disease) without having heartburn? _____ http://www.webmd.com/heartburn-gerd/rm-quiz-heartburn-myths-and-facts 2. Read the text and answer the questions below. If you’ve had heartburn, you know that burning feeling in your lower chest. But despite what it’s called and where it hurts, the pain has nothing to do with your heart. Heartburn happens when a muscle at the end of your esophagus doesn’t close properly. Stomach acid creeps back up that pipe, causing irritation. It’s a common problem: About 40% of adults in the United States have heartburn at least once a month. Along with discomfort, you may also have a bitter or sour taste in your mouth and throat. Symptoms can last from a few minutes to a few hours. When you chew gum, your mouth makes more spit. That acts as a buffer to acid. You also swallow more when you chew gum, and that pushes acid down. Smoking can make things worse. You’re likely to make less spit and more stomach acid. If your heartburn is worse when you lie down, try raising the head of your bed so your head and chest are higher than your feet. But don’t do it with pillows. That can put your head at an angle that can put more pressure on your stomach, making things worse. Instead, try putting 6-inch blocks under the bed posts at the head of the bed. Sleeping on your left side also can help. Studies show lying on your right side can make heartburn worse. The left position seems to put less pressure on the muscle connecting your stomach and esophagus. Numbers on the scale matter more than what you eat. Pressure on your stomach from too much weight can allow acid up into your esophagus. A study by doctors at Stanford University who reviewed more than 2,000 studies about heartburn found no evidence that giving up foods makes it better. But losing a few pounds really does help. If you know something gives you heartburn, don’t eat or drink it. 24 You set yourself up for heartburn when you overeat, and lying down after a meal makes it worse. Tight clothing, control top panty hose, and body shapers can also put pressure on your tummy, so if you’re worried about it, wear loose-fitting, comfortable clothes. Antacids that you can buy at the drugstore can give you quick relief, but if you depend on them too much, they may cause other problems: constipation or diarrhea. Look for the kinds that contain magnesium hydroxide or aluminum hydroxide. They are less likely to cause digestion problems. It’s never a good idea to go to bed on a full stomach. Spreading out the time between dinner and hitting the sack will give stomach acid time to settle. Don’t rush your meals, and don’t eat so much that you are uncomfortable. Try eating four or five smaller meals instead of three large ones. If you have heartburn more than twice a week, you might have something called GERD (gastroesophageal reflux disease). Heartburn is a symptom of GERD, but not always. Hoarseness, a dry cough, trouble swallowing and asthma symptoms are also signs of GERD. Many people take nonprescription antacids for mild or occasional heartburn. Antacids neutralize some of the stomach acid for 30 minutes to 2 hours. Antacids work faster than acid reducers (H2 blockers), but their effect does not last more than 1 to 2 hours. Acid reducers, also called histamine receptor (or H2) blockers can provide relief for up to 12 hours. They decrease the amount of acid that the stomach makes, which may reduce irritation to the stomach lining and decrease heartburn. http://www.webmd.com/heartburn-gerd/features/11-meal-planning-tips-prevent-heartburn 1) 2) 3) 4) 5) 6) 7) 8) When does heartburn happen? What are the symptoms of heartburn? What can make the symptoms better or worse? Why shouldn’t you sleep with a lot of pillows when you have heartburn? Why can sleeping on your left help when you have heartburn? What is the connection between heartburn and overweight? What are the signs of GERD? How can mild heartburn be treated? VOCABULARY DEVELOPMENT 1.4.2 Foods to eat and avoid for heartburn (V) What can you eat and what should you avoid if you have heartburn. Put the following foods into the correct column. 1. banana 6. fish & chips 11. alcoholic beverages 2. tomato sauce 7. orange juice 12. ginger 16. butter 17. fennel 3. herbal tea 8. bean 13. caffeinated drinks (coffee, tea) 18. couscous and rice 4. vinegar 9. chili 14. chewing gum 5. oat 10. milk 15. chocolate 19. celery/parsley 20. ice cream http://www.webmd.com/heartburn-gerd/ss/slideshow-heartburn-foods 25 You should eat You should avoid SPEAKING 1.4.3. Student-patient communication (S) 1. With a partner discuss the possible questions a doctor may ask about symptoms regarding duration, severity, location, causes, timing of the symptoms, past medical history, medication, allergies/adverse reactions, smoking/drug and alcohol history, screening tests. Write your questions into the table then in groups discuss them. POSSIBLE QUESTIONS Duration Severity Location Causes Timing Past medical history Medication 26 Allergies/adverse reactions Smoking/drug and alcohol history Screening tests http://www.rightdiagnosis.com/diagnosis/questions-doctor-ask.htm 2. With a partner, act out the roles below. Student A: Számoljon be orvosának éjszaka jelentkező gyomorégéséről. Nagyon stresszes életmódot folytat. Nem táplálkozik rendszeresen és leginkább gyorsételeket fogyaszt. Ön dohányzik és túlsúlyos is. Kérje ki orvosa véleményét a helyes táplálkozással kapcsolatban. Student B: Ön orvos. Kérdezze ki beszédpartnerét a tünetekről, étkezési szokásairól, életmódjáról. Javasoljon néhány készítményt a panaszok enyhítésére, illetve adjon tanácsot a probléma megelőzéséhez. Sorolja fel azokat az ételeket, melyeket szabad fogyasztani, illetve azokat, amiket el kell kerülni. Javasolja betegének, hogy kezdjen el fogyókúrázni, mozogjon rendszeresen. READING 1.4.4 Other diseases of the stomach (R) 1. Find the description to each condition. Write the correct number into the table. 1) Inflammation of the stomach, often causing nausea and/or pain. It can be caused by alcohol, certain medications, H. pylori infection, or other factors. 2) It refers to painful sores in the lining of the stomach or first part of the small intestine, called the duodenum. 3) It is a disease in which stomach cells become malignant (cancerous) and grow out of control, forming a tumor. 27 4) It occurs when stomach contents flow back up into the esophagus—the muscular tube that carries food and liquids from the mouth to the stomach. It is also called acid reflux or acid regurgitation, whereas GERD is a disease that includes acid reflux as a symptom. 5) People who have this disease develop tumors known as gastrinomas in the pancreas and duodenum. The gastrinomas secrete the hormone gastrin. Because gastrin creates excessive stomach acid, patients can also develop stomach and duodenal ulcers. Condition Description Symptoms GER(D) Gastric ulcer (Stomach ulcer)/ Peptic ulcer Gastritis Stomach (Gastric) cancer Zollinger-Ellison syndrome (ZES) http://digestive.niddk.nih.gov/ddiseases/pubs/gerd/#GERD http://www.webmd.com/digestive-disorders/digestive-diseases-peptic-ulcer-disease http://www.webmd.com/digestive-disorders/digestive-diseases-gastritis http://www.webmd.com/cancer/understanding-stomach-cancer-basics http://www.webmd.com/cancer/stomach-gastric-cancer http://digestive.niddk.nih.gov/ddiseases/a-z.aspx 2. Match the symptoms with the diseases above. Some symptoms can fit more than one disease. a. A gnawing or burning pain in the middle or upper stomach between meals or at night b. Hiccups e. Black, tarry stools f. Nausea or vomiting i. Difficulty swallowing (dysphagia) j. Vomiting blood c. Chest pain g. Regurgitation of food or sour liquid k. Bloating in the stomach after eating d. Hoarseness or sore throat h. Recurrent upset stomach l. Weakness or/and fatigue 28 WRITING 1.4.5 Answering patient’s email (W) You are working for Patients’ Forum Europa. You get the following email from a patient. Reply the email in which you try to calm her down tell him/her possible diseases she may have the need for urgent medical help tests needed to identify the problem (blood test, ultrasound, endoscopy) Dear Dr. Patients’ Forum Europa, I am feeling very ill. I have a pain on my right side, just under the ribs, I also have a gentle burning sensation across my lower abdomen. There has been a slight change in my bowel movements, either slightly constipated or else a little loose, some are mostly normal but have darker greyish patches and some are very dark all over. My main problem is extreme weakness, I can do very little some days without having to lie down. Some days I feel sick and have difficulty eating. I have nause and sometimes vomiting. I am not sure, but last time it looked like blood. I am terrified that I have cancer, but could it be a bleeding ulcer, just can't understand this extreme weakness and it'sreally getting me down. I would really appreciate any help or advice. Many thanks Julie Dear Julie, _________________________________________________________________________________ _________________________________________________________________________________ _________________________________________________________________________________ _________________________________________________________________________________ _________________________________________________________________________________ _________________________________________________________________________________ _________________________________________________________________________________ Regards Dr. Patients’ Forum Europe http://www.patient.co.uk/forums/discuss/bleeding-ulcer-and-fatigue-103875 29 LISTENING 1.4.6. Endoscopy (L) Listen to the recording and answer the questions below. 1) 2) 3) 4) 5) What is an upper GI endoscopy? What does this surgical procedure involve? What does an endoscope consist of? Why can this procedure be necessary? How is the operation performed? Write down the steps. Step 1: Step 2: Step 3: Step 4: Step 5: Step 6: Step 8: Step 9: Source: http://www.youtube.com/watch?v=pBCtwHNrGYM SPEAKING 1.4.7 Explaining endoscopy to the patient (S) With a partner, act out the roles below. Student A: You are a doctor. Your patient (Student B) has to undergo endoscopy because he/she shows signs and symptoms of stomach ulcer. Explain him/her: what is endoscopy why there is need for endoscopy the procedure itself Student B: You are a patient. You need endoscopy. You are very afraid of the procedure. You aks your doctor about: reasons procedure if sedation is applied (to avoid pain, discomfort) 30 UNIT 2. DIGESTIVE SYSTEM II. (SMALL AND LARGE INTESTINES, LIVER) Aims of the Unit In this unit you will learn about: the small and the large intestines, diseases of the small and large intestines and the liver. 31 2.1 SMALL AND LARGE INTESTINES READING 2.1.1 Small Intestine (R) 1. Read the text about the small intestine and complete the sentences below with the missing information. Chyme released from the stomach enters the small intestine, which is the primary digestive organ in the body. Not only is this where most digestion occurs, it is also where practically all absorption occurs. The longest part of the alimentary canal, the small intestine is about 3.05 meters long in a living person. Since this makes it about five times longer than the large intestine, you might wonder why it is called “small.” In fact, its name derives from its relatively smaller diameter of only about 2.54 cm, compared with 7.62 cm for the large intestine. In addition to its length, the folds and projections of the lining of the small intestine work to give it an enormous surface area, which is approximately 200 m2, more than 100 times the surface area of your skin. The small intestine is subdivided into three regions. From proximal (at the stomach) to distal, these are the duodenum, jejunum, and ileum. The shortest region is the 25.4-cm duodenum. It takes in semi-digested food from your stomach through the pylorus, and continues the digestion process. The duodenum also uses bile from your gallbladder, liver, and pancreas to help digest food. The jejunum is about 0.9 meters long (in life) and runs from the duodenum to the ileum. Jejunum means “empty” in Latin and supposedly was so named by the ancient Greeks who noticed it was always empty at death. It carries food through rapidly, with wave-like muscle contractions, towards the ileum. Ileum is the last section is the longest part of your small intestine, measuring about 1.8 meters in length. It is thicker, more vascular, and has more developed mucosal folds than the jejunum. The ileum joins the cecum, the first portion of the large intestine, at the ileocecal sphincter (or valve). The ileum is where most of the nutrients from your food are absorbed before emptying into the large intestine. The small intestine has three features which allow it to have such a huge absorptive surface area packed into a relatively small space: Mucosal folds: The inner surface of the small intestine is not flat, but thrown into circular folds. This not only increases the surface area, but helps regulate the flow of digested food through your intestine. 32 Villi: The folds form numerous tiny projections which stick out into the open space inside your small intestine (or lumen), and are covered with cells that help absorb nutrients from the food that passes through. Microvilli: The cells on the villi are packed full of tiny hairlike structures called microvilli. This helps increase the surface of each individual cell, meaning that each cell can absorb more nutrients. http://cnx.org/content/m46512/latest/ http://cnx.org/content/m46512/latest/ The small intestine is the organ in the body where 1.____________________ and 2.____________________ occur. The small intestine is about 3.____________________ long and 4. ____________________ wide. Its entire surface is approximately 5.____________________. The small intestine is made up of three segments: 6.____________________, 7.____________________, 8.____________________. The shortest region is the duodenum. It takes in 9.____________________ from your stomach through the 10.____________________, and continues the digestion process. To help digest food it uses 11.____________________ from your gallbladder, liver, and pancreas. The jejunum carries food through rapidly, with 12. ____________________, towards the ileum. The ileum is where 13.____________________ before emptying into the large intestine. The features, which increase the absorptive surface area of the small intestine include: 14.____________________, 15.____________________, 16. ____________________. 2. Talk about the small intestine with the help of the prompts below. function size parts function of the parts the absorptive surface of the small intestine 33 READING 2.1.2 Large Intestine (R) Read the text about the large intestine and label the diagram. The large intestine is the terminal part of the alimentary canal. The primary function of this organ is to finish absorption of nutrients and water, synthesize certain vitamins, form feces, and eliminate feces from the body. The large intestine runs from the appendix to the anus. It frames the small intestine on three sides. The large intestine is subdivided into four main regions: the cecum, the colon, the rectum, and the anus. The ileocecal valve, located at the opening between the ileum and the large intestine, controls the flow of chyme from the small intestine to the large intestine. The cecum is a pouch-like dead-end passage that branches inferiorly from the end of the ileum. Fecal matter entering the large intestine from the ileum passes into the cecum before being pushed superiorly into the ascending colon. The appendix is attached to the inferior end of the cecum and is believed to store beneficial bacteria that help break down undigested food. Fecal matter passes from the cecum into the colon, the largest region of the large intestine. The ascending colon carries feces superiorly from the cecum to the transverse colon. The transverse colon then carries feces transversely from the right side of the abdomen to the left side, where it enters the descending colon. Next, the descending colon carries the feces inferiorly to the S-shaped sigmoid colon and rectum. The rectum stores feces until they are ready to be defecated. During defecation, the anal sphincter muscles of the anal canal relax to allow feces to exit the body. http://cnx.org/content/m46512/latest/ 34 LISTENING 2.1.3 Appendix and appendicitis (L) 1. Discuss the following questions. What is the function of the appendix? What kind of disease is appendicitis? 2. Some researchers say, they have found the true function of the appendix. Watch the video and find it out. https://www.youtube.com/watch?v=a2BtkMSijUc 3. Listen to the recording about appendicitis and answer the questions below. 1) When can appendicitis happen? 2) What are the symptoms of appendicitis? 3) What is the cause of appendicitis? 4) How many types of surgery are there for appendicitis? 5) What can happen when the inflamed appendix is not removed? 6) What is the infection in the lining of the abdomen called? https://www.youtube.com/watch?v=xmBtu7S4fgI 35 WRITING 2.1.4 Asking questions about the large intestine (W) Write questions to the answers. 1. ______________________________________________________________________________ The primary function of the large intestine is to finish absorption of nutrients and water, synthesize certain vitamins, form feces, and eliminate feces from the body. 2. ______________________________________________________________________________ The cecum, the colon, the rectum, and the anus. 3. ______________________________________________________________________________ The flow of chyme from the small intestine to the large intestine. 4. ______________________________________________________________________________ It stores beneficial bacteria that help break down undigested food. 5. ______________________________________________________________________________ Ascending colon, transverse colon, descending colon, sigmoid colon and rectum. 6. ______________________________________________________________________________ It stores feces. 7. ______________________________________________________________________________ The anal sphincter muscles of the anal canal relax to allow feces to exit the body. http://cnx.org/content/m46512/latest/ 36 VOCABULARY DEVELOPMENT 2.1.5 Important vocabulary of the small and large intestines (V) 1. Label the following diagram. http://www.enchantedlearning.com/subjects/anatomy/digestive/ 2. Match the words (a-l) with the explanations (1-12). a a) b) c) d) e) f) g) h) i) j) k) l) b c d e f g h i j k l bacterial flora appendix ascending colon cecum colon circular fold duodenum gastrocolic reflex ileum jejunum microvillus villus 37 1) 2) 3) 4) 5) 6) 7) 8) 9) 10) 11) 12) small projection of the plasma membrane of the absorptive cells of the small intestinal mucosa coiled tube attached to the cecum end of the small intestine between the jejunum and the large intestine middle part of the small intestine between the duodenum and the ileum projection of the mucosa of the small intestine pouch forming the beginning of the large intestine deep fold in the mucosa and submucosa of the small intestine first part of the small intestine, which starts at the pyloric sphincter and ends at the jejunum first region of the colon part of the large intestine between the cecum and the rectum bacteria in the large intestine propulsive movement in the colon activated by the presence of food in the stomach http://www.enchantedlearning.com/subjects/anatomy/digestive/ 2.2 DISEASES OF THE SMALL AND LARGE INTESTINES VOCABULARY DEVELOPMENT 2.2.1 Collecting ideas to food poisoning (V) Collect words and expressions to the term ‘food poisoning’ then compare your ideas in groups of 3. Food Poisoning SPEAKING 2.2.2 FAQs about food poisoning (S) Work in pairs. Discuss the following questions. 1) 2) 3) 4) 5) 6) 7) What is food poisoning? When do the signs and symptoms appear? What are the most common symptoms of food poisoning? What foods are more susceptible to contamination? How can food become contaminated? How is mild food poisoning treated? Do you know any home remedies? When do you need to visit your GP? 38 READING 2.2.3 Food poisoning facts (R) Read the text about food poisoning and check your answers above. Food poisoning is an illness caused by eating contaminated food. Most people get better without the need for treatment. In most cases, food that causes food poisoning is contaminated by bacteria, such as salmonella or Escherichia coli (E. coli), or a virus, such as the norovirus. The symptoms of food poisoning usually begin 1-3 days after eating contaminated food. They include: feeling sick vomiting diarrhoea stomach cramps Some toxins can cause food poisoning within a much shorter time. In these cases, vomiting is the main symptom. Foods particularly susceptible to contamination if not handled, stored or cooked properly include: raw meat and poultry raw eggs raw shellfish unpasteurised milk 'ready to eat' foods, such as cooked sliced meats, soft cheeses and pre-packed sandwiches How is food contaminated? Food can become contaminated at any stage during production, processing or cooking. For example, food poisoning can be caused by: not cooking food thoroughly not storing food that needs to be chilled at below 5°C correctly leaving cooked food for too long at warm temperatures someone who is ill or who has dirty hands touching the food eating food that has passed its ‘use by’ date cross-contamination (the spread of bacteria, such as E. coli, from contaminated foods) Treating food poisoning Most people with food poisoning get better without the need for treatment. To help relieve your symptoms you should rest and drink plenty of fluids. It is best to avoid food until you feel much better. When you start eating again, choose foods that are easily digested, such as toast. It's important that you do not become dehydrated because it will make you feel worse and lengthen your recovery. Try to drink as much water as you can, even if you can only sip it, particularly every time you pass diarrhoea. Oral rehydration salts (ORSs) are recommended for people vulnerable to the effects of dehydration, such as the elderly and those with another health condition. Visit your GP or accident and emergency (A&E) department if you are severely dehydrated – for example, if you have sunken eyes and you are unable to urinate. Antibiotics may be prescribed if test results show 39 the source of your food poisoning was bacterial, and your symptoms are severe or last longer than 3– 4 days. http://www.nhs.uk/Conditions/Food-poisoning/Pages/Introduction.aspx SPEAKING 2.2.4 Doctor-patient conversation (S) With a partner, act out the roles below. Student A: You are a patient. You have severe food poisoning. Talk about: Student B: You are a doctor. After asking about the symptoms talk to Student B about: the symptoms onset of the symptoms what you ate, suspect food explain briefly what food poisoning is possible causes treatment recommendations to avoid further poisoning treatment suggestions LISTENING 2.2.5 Diarrhoea (L) Listen and complete the text with the missing words. Source: https://www.youtube.com/watch?v=4XS0SbCGJCk Hello, I'm Dr Rupal Shah. I'm a GP at the Bridge Lane Group Practice in Battersea in London. A practical way to define diarrhoea is 1. ________________ ________________ which are looser or more frequent than is usual for you. If the diarrhoea's caused by an infection, you might find that you also have a fever or nasty stomach 2. ________________. Diarrhoea can cause a problem if it's very frequent and it results in you becoming dehydrated, so it's always important to make sure you are maintaining an adequate 3. _______________ _______________ whilst you're suffering from the symptoms. There's many causes of diarrhoea and it's difficult to list all of them. There's different causes according to how old you are, for example. A lot of diarrhoea is caused by an infection which you can pick up from food or from contact with somebody else who's 4.________________ If you're quite unwell with the diarrhoea, for example if there's blood in the diarrhoea or if you have a high 40 fever or are generally unwell, then it's worth 5. _______________ a second opinion. Although there are many different causes of diarrhoea in children, the most common cause is certainly infections. It's important to remember that treatments which can be used safely in adults, like Imodium, shouldn't be given to children. For adults and children, if the diarrhoea's 6. _______________ for more than a few days or seems particularly severe, then it's worth going to see your GP. Your GP might want to do further tests, they might want to send a sample of stool off to the lab, they might want to 7. ______________ for you to have some blood tests. It depends on your particular circumstances. Most cases of diarrhoea are 8. _______________. They last for a few days and then get better. It's embarrassing and unpleasant whilst it lasts, but rarely serious. http://www.nhs.uk/Conditions/Diarrhoea/Pages/Introduction.aspx READING 2.2.6 Other common gastrointestinal diseases (R) Match the common gastrointestinal diseases (1-4) with the descriptions (A-D). 1) 2) 3) 4) Crohn’s disease Ulcerative Colitis Celiac disease IBD A. ________________________________________ It is a functional gastrointestinal disorder, meaning symptoms are caused by changes in how the GI tract works. People with a functional GI disorder have frequent symptoms; however, the GI tract does not become damaged. It is a group of symptoms that occur together, not a disease. The most common symptoms are abdominal pain or discomfort, often reported as cramping, along with changes in bowel habits. B. ________________________________________ It is a disease that causes inflammation, or swelling, and irritation of any part of the digestive tract. The part most commonly affected is the end part of the small intestine, called the ileum. In this disease, inflammation extends deep into the lining of the affected part of the GI tract. Swelling can cause pain and can make the intestine empty frequently, resulting in diarrhea. Chronic - or long-lasting inflammation may produce scar tissue that builds up inside the intestine to create a stricture. The cause of Crohn’s disease is unknown, but researchers believe it is the result of an abnormal reaction by the body’s immune system. Researchers believe that in this disease the immune system attacks bacteria, foods, and other substances that are actually harmless or beneficial. C. ________________________________________ It is a chronic, or long-lasting, disease that causes inflammation and sores, called ulcers, in the inner lining of the large intestine, which includes the colon and the rectum—the end part of the colon. Normally, the large intestine absorbs water from stool and changes it from a liquid to a solid, but the inflammation causes loss of the lining of the colon, leading to 41 bleeding, production of pus, diarrhea, and abdominal discomfort. The cause of it is unknown though theories exist. According to these people have abnormalities of the immune system, but whether these problems are a cause or a result of the disease is still unclear. D. ________________________________________ It is a digestive disease that damages the small intestine and interferes with absorption of nutrients from food. People cannot tolerate gluten, a protein in wheat, rye, and barley. When foods or products are eaten that contain gluten, the immune system responds by damaging or destroying villi. Without healthy villi, a person becomes malnourished, no matter how much food one eats. Symptoms may occur in the digestive system or in other parts of the body. Common digestive symptoms include: abdominal bloating and pain, chronic diarrhea, vomiting, constipation, weight loss. http://digestive.niddk.nih.gov/ SPEAKING 2.2.7 Doctor-patient conversations (S) With a partner, act out the roles below. Student A: You are a doctor. Ask Student B about: onset of the symptoms the symptoms food eaten Talk to Student B about: possible causes refer him/her to blood test, colonoscopy Student B: You are a patient. You turn to your GP for advice. You have suffered from abdominal discomfort and gastric symptoms for several weeks. You get diarrhoea, constipation, mucousy stools. Your stomach makes constant noises and gurgling, and you have occasional vomiting. Answer the doctor’s questions. 42 WRITING 2.2.8 Most common gastrointestinal diseases: an essay (W) Write an essay (250-300 words) about the most common gastrointestinal diseases, possible causes, symptoms, treatments, prevention. __________________________________________________________________________________ __________________________________________________________________________________ __________________________________________________________________________________ __________________________________________________________________________________ __________________________________________________________________________________ __________________________________________________________________________________ __________________________________________________________________________________ __________________________________________________________________________________ __________________________________________________________________________________ __________________________________________________________________________________ __________________________________________________________________________________ __________________________________________________________________________________ __________________________________________________________________________________ __________________________________________________________________________________ __________________________________________________________________________________ __________________________________________________________________________________ __________________________________________________________________________________ __________________________________________________________________________________ __________________________________________________________________________________ __________________________________________________________________________________ 2.3 THE LIVER SPEAKING 2.3.1 FAQs about the liver (S) With a partner discuss the questions below. 1) 2) 3) 4) What are the major functions of the liver? What causes liver damage? Do you know any diseases of the liver? Do you know any food that cleans the liver? 43 VOCABULARY DEVELOPMENT 2.3.2 Anatomy of the liver (V) 1. Label the diagram with the help of the words in the box. right and left hepatic gall bladder duct liver right lobe pancreatic duct stomach esophagus duodenum common hepatic duct falciform ligament liver lobe liver left lobe cystic duct pancreas http://en.wikipedia.org/wiki/Liver 2. Find out the functions of the liver. Complete the expressions with the verbs from the box. produce (2x) store 1) 2) 3) 4) 5) 6) 7) 8) 9) 10) maintain fight make metabolize excrete aid break down _______________ digestion _______________ vital nutrients _______________ waste materials _______________ the breakdown products of digestion _______________ iron _______________ the hormonal balance _______________ infections _______________ cholesterol and other fats _______________ the stored glycogen into glucose _______________ bile 44 LISTENING 2.3.3 Functions of the liver (L) Read the text about the liver and complete it with the missing words. The first letter is given in each word. Then listen and check your answers. Source: http://www.youtube.com/watch?v=O71niTozP-o Liver is the most used internal part of the human body. One can understand how the liver functions and aids the digestion of food in humans, apart from it producing vital nutrients and helping any 1. e _______________ (9letters) of waste material from the body. The liver is the largest organ in the human body. The liver alone weighs about one and a half to three kilograms in the body. The liver occupies much of the upper right quadrant of the 2. a_______________(6letters) to the right of the stomach and immediately below the 3. d_______________(9letters). The liver is divided into two unequal lobes: a large right lobe and a smaller left lobe. Liver plays a number of vital roles such as metabolizing the breakdown products of digestion and detoxifying substances that are 4. h_______________(7letters) to the body. The liver also provides essential energy-producing substances and supplies vital 5. v_______________(8letters) including iron, vitamin B12 and copper. Liver controls the production and excretion of cholesterol and metabolizes alcohol into mild toxin. It also performs many important functions including storing iron, maintaining the hormonal balance, producing immune factors to fight infections, regulating 6. b_______________(5letters) clotting and producing bile. The hepatic portal veins, triplet vessels that carry blood from the gastro-intestinal tract and spleen to the liver pick-up nutrients, send toxins from the stomach and intestines for processing. The hepatic ducts in gallbladders send the processed bile to the 7. d_______________(8letters), which is about 25 cm long and meaty. The stomach opens up to the deudenum through the pyloric sphincter, a muscle the acts as a valve that controls the passage of food from the stomach into the small intestine. The abdominal aorta and hepatic veins supply and return blood in the liver. One of the most important functions of the liver is to produce 8. b_______________(4letters). This digestive juice dissolves fat into watery contents much like detergents dissolves grease. This juice is stored in the gall bladder until it is needed, then it is sweezed out of the gall bladder through the bile ducts and into the intestines to mix with the fat in the blood through the bile ducts. When food, medicines, etc. are 9. c_______________(8letters) are digested, the cells within the liver that contain a number of powerful enzymes break them down into many toxins. Ammonia, a toxin product arising from the digestion of the proteins, is converted into the less toxic urea by liver. During exercise, the liver quickly breaks down the stored glycogen into glucose, which is released into the blood stream to be used by muscles as a source of 10. e_______________(6letters). Another function of the liver is to make cholesterol and other fats that are needed by the body. Maintaining a healthy digestive system is essential for the health of the liver and other organs so that they can continue to perform their daily tasks. 45 WRITING 2.3.4 An interview about the diseases of the liver (W) Read the following interview with one of the leading experts of liver diseases. Play the role of the reporter and find out the questions for the answers. Rep.: Good Morning. Our guest is today Dr. George Smith, leading U.S. expert of liver diseases. Thank you very much for accepting our invitation. Dr. G.S.: Good Morning. I am glad to be here today to talk about this very serious topic which affets millions of U.S. citizens. Rep.: My first question is a general one. 1. _____________________________________________ Dr. G.S.: Liver disease is any abnormal process that affects the liver. The more severe the liver disease, the greater the effect on liver function. It is true that with the loss of 75% of the liver's function the liver cannot keep up with its required functions and it begins to fail. Rep: 2. _____________________________________________ Dr. G.S.: Alcohol abuse is the most common cause of liver disease in North America. Alcohol is directly toxic to liver cells and can cause inflammation, referred to as alcoholic hepatitis and cirrhosis due to extreme scarring of the liver. Rep: 3. _____________________________________________ Dr. G.S.: Jaundice is a sign of liver, gallbladder, or certain blood disorders. Bilirubin, which is normally removed from the blood by the liver and excreted in bile and stool, increases in the blood. The skin and the eyes become yellow due to the buildup of bilirubin. The urine becomes dark from the excretion of bilirubin, and the stool becomes clay-colored due to the absence of bilirubin. Rep: 4. _____________________________________________ Dr. G.S.: Acetaminophen in excess can cause liver failure that often is permanent and results in death. Numerous antibiotics and statins may cause liver inflammation and failure. Excessive amounts of vitamin A can cause hepatitis, cirrhosis, and liver failure. Additionally, many mushrooms are poisonous to the liver, and eating unidentified mushrooms gathered in the woods can be lethal due to liver failure. Rep: 5. _____________________________________________ Dr. G.S.: Yes, hepatitis is a form of liver disease. The term hepatitis means "inflammation of the liver," and liver cells can become inflamed for many reasons, including alcohol, drugs, toxins, and infections. Rep: 6. _____________________________________________ Dr. G.S.: Cirrhosis is a late-stage of liver disease. Diseases that lead to cirrhosis injure and kill liver cells. Inflammation and repair associated with the dying liver cells causes scar tissue to form. Progressive scarring leads to cirrhosis. Liver failure and liver cancer are complications of cirrhosis. Rep: 7. _____________________________________________ Dr. G.S.: Liver biopsy, in which a sample of liver tissue is removed and analyzed under the microscope, is the only test that can confirm a diagnosis of cirrhosis. Rep: 8. _____________________________________________ Dr. G.S.: Hepatitis C is the most common cause of chronic viral hepatitis in the U.S. It is passed from person to person sexually, particularly through male homosexual activities and by use of illicit, injectable drugs. It also may be passed from mother to infant at the time of birth. Hepatitis B is the 46 second most common cause of chronic hepatitis in the U.S. Hepatitis D is a chronic viral infection of the liver but occurs only in a small proportion of individuals with chronic hepatitis B. Hepatitis A and E cause primarily acute hepatitis and not chronic hepatitis. Rep: 9. _____________________________________________ Dr. G.S.: The liver is a critical organ for many bodily functions. Interference with liver function results in excessive bleeding, jaundice, sensitivity to the effects of drugs, and toxic effects on the brain. Interference with the production of blood proteins and the elimination of water and salt result in the accumulation of fluid in the tissues of the body, referred to as edema. Rep: 10. _____________________________________________ Dr. G.S.: The liver itself does not sense pain. Because of this, the liver can be cut, burned, or compressed without causing the sensation of pain. Inside the tissue that encapsulates the liver, there are pain fibers which are stimulated when the liver is stretched. This means that anything the causes the liver to stretch can cause liver pain. Rep: Dr Smith, thank you very much for your detailed explanations. Dr. G.S.: You are welcome. Thank you for the invitation. http://www.medicinenet.com/liver_disease_quiz/quiz.htm READING 2.3.5 Facts about the liver (R) Decide if the statements are true or false. 1. The liver is the second largest organ in the human body. True__ False__ 2. Bile is a liquid made in the liver that helps break down fats and other nutrients. True__ False__ 3. Just like the heart and kidneys, under no circumstances can the liver ever regenerate itself. True__ False__ 4. The liver makes protein and it also stores glucose, vitamin B12 and iron. True__ False__ 5. The liver is located under the ribs on the left side. True__ False__ 6. Even though it does its best, the liver is unable to save up energy. True__ False __ 7. Shaped like a football that is flat on one side, the adult liver weighs about three pounds. True__ False__ 8. Although it is capable of doing a lot of things, the liver plays no role in stopping someone from bleeding. True__ False__ 9. Alcohol can damage or destroy liver cells, but a person who has liver disease can still practice moderation by drinking a glass or two of alcohol every day. True__ False__ 10. If someone is overweight or obese, it doesn’t affect the health of that person’s liver. True__ False__ 11. The health of a person’s liver is determined by conducting various blood tests. True__ False__ 12. It may be difficult to believe, but the liver helps to build muscle. True__ False__ 47 13. In a polluted environment, the liver isn’t able to protect a person’s body. True__ False __ 14. Primary liver cancer (cancer that starts in the liver) is one of the few cancers on the rise in the United States. True__ False __ 15. Basic over-the-counter medicines can’t affect the liver. True__ False _ http://www.liverfoundation.org/education/liverlowdown/ll0913/tfliverinfo/ http://ubcclf.com/liveright-blog-series-challenge-your-misconceptions SPEAKING 2.3.6 Talking about the liver (S) In pairs talk about the liver with the help of the prompts. Take turns. place weight lobes functions dieseases of the symptoms/treatment) prevention of liver diseases liver (causes, 48 2.5 VOCABULARY absorption appendix alimentary bolus alimentary tract antrum ascending colon bicuspid bilirubin bloating body bolus bounded by buccal canine cardia cecum cementum chief cell circular fold circular muscle cirrhosis cleft lip coiled colon conduit conical cuspid cystic duct defecate dentin descending colon detoxicate duct duodenum dysphagia edema enamel enteroendocrine cell esophagus excrete expectoration falciform ligament fatigue flatus fold frenulum felszívódás féregnyúlvány táplálkozási bolus tápcsatorna antrum, tágulat, kamra felszálló vastagbél kétcsücskű bilirubin puffadás gyomortest megrágott étel hátáros valamivel szájüreg, száji szemfog gyomorszáj vakbél fogcement fősejt (pepszintermelő sejt) cirkuláris redők cirkuláris simaizom májzsugorodás nyúlszáj összecsavart, összetekercselt vastagbél csatorna, cső kúp alakú, kónikus szemfog epehólyag kivezető csöve ürít dentin leszálló vastagbél méregtelenít vezeték, kivezető cső nyombél/patkóbél nyelési zavar ödéma zománc enteroendokrin sejt nyelőcső kiválaszt köpet, köpés sarló alakú szalag fáradtság orv. szél gyűrődés, ránc szalagocska 49 fundus gastrin gastrinoma gingiva glandular gums hard palate hepatichiatal hernia hoarseness ileocecal valve ileum illicit incisor inner oblique muscle interference jaundice jawbone jejunum junction lesion lining lipase lobe longitudional muscle mastication mesentery molar mucosa mucus noma oral vestibule oropharynx palate pancreatic duct papilla parietal cell periodontal periodontal (gum) disease portal vein pouch pout premolar propulsion pulp pus pylorus rear fundus gasztrin gasztrinóma fogíny mirigyes, mirigyszerű íny kemény szájpadlás máj rekeszizomsérv rekedtség ileocoecalis billentyű csípőbél tiltott metszőfog belső ferde hasizom beavatkozás, zavaró hatás sárgaság állkapocs-csont éhbél érintkezés, elágazás sérülés, károsodás barázda lipáz lebeny hosszanti izom rágás bélfodor örlőfog, zápfog, záp-, örlőnyálkahártya nyálka noma szájüreg előcsarnoka száj-garat szájpadlás hasnyálmirigy kivezető csöve papilla parietális sejt periodontális fogágybetegség májkapu-véna, kapuvéna erszény, zacskó ajkat biggyeszt előzápfog, kisőrlőfog előre mozgatás, hajtás pulpa, lágy szövet genny gyomorzár hátsó rész 50 regurgitation respiratory conduit rugae salivation sigmoid colon soft palate sore specimen sphincter statin stricture submandibular gland tonsil transverse colon trigone urea uvula vascular membrane vaulted verstibule zymogen felöklendezés légúti csatorna nyálkahártyaredők nyálképződés szigmabél lágy íny fekélyes seb minta záróizom sztatin szűkület submandibularis mirigy mandula haránt vastagbél trigonum karbamid uvula, nyelvcsap érrendszeri membrán íves, boltíves vestibulum, bejárat zimogén 51 UNIT 3. NERVOUS SYSTEM Aims of the Unit In this unit you will learn about: the central nervous system, cranial and spinal nerves, common diseases of the central nervous system such as Alzheimer’s disease, peripheral nervous system and mental illnesses. 52 3.1 THE CENTRAL NERVOUS SYSTEM READING 3.1.1 Brain Quiz (R) How much do you know about the human brain? Do the quiz. Write T (True) or F (False). 1) The average human brain is made up of water up to 80%. __________ 2) After age 30, the brain shrinks exactly 25% in mass each year. __________ 3) The brain feels pain compared to the rest of the body. __________ 4) The energy used by the brain is enough to light a 25 watt light bulb. __________ 5) Your skull is made up of 28 bones. __________ 6) When you laugh eight differenct areas in our brain are in action. __________ 7) The differences in brain weight and size change mental abiltiy. __________ 8) The human brain is so soft that a table knife would be more than enough to slice through it. __________ 9) Every time you recall a memory or have a new thought a new connection is made. __________ 10) The brain is the fattiest part of the body with a fat content of around 60%. __________ +1. The brain can stay alive 1-3 minutes without any oxygen. __________ http://www.proprofs.com/quiz-school/story.php?title=true-false-brain-quiz#READING VOCABULARY DEVELOPMENT 3.1.2 Brain Anatomy (R) Complete the text with the missing words from the box. sulcus secretion internal clock spinal cord bundle cranial nerves skull nuclei white matter hemispheres 53 The nervous system is divided into central and peripheral systems. The central nervous system (CNS) is composed of the brain and 1. _______________. These structures are protected by bone and cushioned from injury by the cerebrospinal fluid (CSF). The peripheral nervous system connects the central nervous system to the rest of the body. The brain is a mass of soft nerve tissue, which is encapsulated within the 2. _______________. It is composed of the cerebrum, cerebellum, and brainstem. The cerebrum is the largest part of the brain and is composed of right and left 3. _______________. It performs higher functions like interpreting touch, vision and hearing, as well as speech, reasoning, emotions, learning, and fine control of movement. The peripheral or outer part of the cerebrum is separated into lobes. Frontal, Parietal, Temporal, Occipital. The cerebellum is located under the cerebrum. Its function is to coordinate muscle movements, maintain posture, and balance. The brainstem includes the midbrain, pons, and medulla. It acts as a relay center connecting the cerebrum and cerebellum to the spinal cord. It performs many automatic functions such as breathing, heart rate, body temperature, wake and sleep cycles, digestion, sneezing, coughing, vomiting, and swallowing. Ten of the twelve 4. _______________ originate in the brainstem. The surface of the cerebrum has a folded appearance called the cortex. The cortex contains about 70% of the 100 billion nerve cells. The nerve cell bodies color the cortex grey-brown giving it its name – gray matter. Beneath the cortex are long connecting fibers between neurons, called axons, which make up the 5. _______________. Each fold is called a gyrus, and each groove between folds is called a 6. _______________. The right and left hemispheres of the brain are joined by a 7. ______________ of fibers called the corpus callosum that delivers messages from one side to the other. Each hemisphere controls the opposite side of the body. Not all functions of the hemispheres are shared. In general, the left hemisphere controls speech, comprehension, arithmetic, and writing. The right hemisphere controls creativity, spatial ability, artistic, and musical skills. The deep structures of the brain are the following: Hypothalamus - is located in the floor of the third ventricle and is the master control of the autonomic system. It plays a role in controlling behaviors such as hunger, thirst, sleep, and sexual response. It also regulates body temperature, blood pressure, emotions, and 8. _______________ of hormones. Pituitary gland - known as the “master gland,” it controls other endocrine glands in the body. It secretes hormones that control sexual development, promote bone and muscle growth, respond to stress, and fight disease. Pineal gland - is located behind the third ventricle. It helps regulate the body’s 9. ________________ and circadian rhythms by secreting melatonin. It has some role in sexual development. Thalamus - serves as a relay station for almost all information that comes and goes to the cortex. It plays a role in pain sensation, attention, alertness and memory. Basal ganglia - includes the caudate, putamen and globus pallidus. These 10. ________________ work with the cerebellum to coordinate fine motions, such as fingertip movements. Limbic system is the center of our emotions, learning, and memory. Included in this system are the cingulate gyri, hypothalamus, amygdala (emotional reactions) and hippocampus (memory). 54 http://www.mayfieldclinic.com/PE-AnatBrain.htm#.U8o7fPl_sgV http://sehati.org/index/patientresources/normalanatomy.html VOCABULARY DEVELOPMENT 3.1.3 Important vocabulary of the CNS (V) 1. Translate the highlighted words into Hungarian. central nervous system peripheral nervous system cerebrum cerebellum brain stem cortex gray matter neuron axons gyrus corpus callosum hypothalamus ventricle pituitary gland pineal gland thalamus basal ganglia caudate putamen globus pallidus limbic system cingulate gyri hypothalamus amygdala hippocampus 55 SPEAKING 3.1.4 Basic structures of the brain (S) Label the basic structures of the brain then talk about them. cerebellum, brainstem, cerebrum http://lrrpublic.cli.det.nsw.edu.au/lrrSecure/Sites/LRRView/7700/documents/5657/5657/applets/001_04_1sa _ap01.htm READING 3.1.5 Brain Anatomy Diagram (R) Read the definitions below then label the brain anatomy diagram. 56 Cerebellum - the part of the brain below the back of the cerebrum. It regulates balance, posture, movement, and muscle coordination. Corpus Callosum - a large bundle of nerve fibers that connect the left and right cerebral hemispheres. In the lateral section, it looks a bit like a "C" on its side. Frontal Lobe of the Cerebrum - the top, front regions of each of the cerebral hemispheres. They are used for reasoning, emotions, judgment, and voluntary movement. Medulla Oblongata - the lowest section of the brainstem (at the top end of the spinal cord); it controls automatic functions including heartbeat, breathing, etc. Occipital Lobe of the Cerebrum - the region at the back of each cerebral hemisphere that contains the centers of vision and reading ability (located at the back of the head). Parietal Lobe of the Cerebrum - the middle lobe of each cerebral hemisphere between the frontal and occipital lobes; it contains important sensory centers (located at the upper rear of the head). Pituitary Gland - a gland attached to the base of the brain (located between the Pons and the Corpus Callosum) that secretes hormones. Pons - the part of the brainstem that joins the hemispheres of the cerebellum and connects the cerebrum with the cerebellum. It is located just above the Medulla Oblongata. Spinal Cord - a thick bundle of nerve fibers that runs from the base of the brain to the hip area, running through the spine (vertebrae). Temporal Lobe of the Cerebrum - the region at the lower side of each cerebral hemisphere; contains centers of hearing and memory (located at the sides of the head). http://www.enchantedlearning.com/subjects/anatomy/brain/label/lateralbrain/label.shtml WRITING 3.1.6 Lobes of the brain (W) 1. Which lobe of the brain does the man in the pictures point at? Write the names below the pictures. 1. __________________ 2. __________________ 3. __________________ 4. __________________ https://faculty.washington.edu/chudler/lobe.html 57 2. The functions of the lobes are listed here. Write the name of the correct lobe after each function. 1) Understanding language (Wernicke’s area) __________ 2) Speech: speaking and writing (Broca’s area) __________ 3) Interprets vision (color, light, movement) __________ 4) Personality, behavior, emotions __________ 5) Spatial and visual perception __________ 6) Sequencing and organization __________ 7) Intelligence, concentration, self-awareness __________ 8) Interprets language, words __________ 9) Body movement (motor strip) __________ 10) Sense of touch, pain, temperature (sensory strip) __________ 11) Interprets signals from vision, hearing, motor, sensory and memory __________ 12) Judgment, planning, problem solving __________ http://lrrpublic.cli.det.nsw.edu.au/lrrSecure/Sites/LRRView/7700/documents/5657/5657/applets/001_04_01_1tl_ap01_text.htm http://www.chakras.org.uk/chakra_yoga_health_mind_brain_lobes.htm 3.2 CRANIAL NERVES LISTENING 3.2.1 Cranial Nerve Song (L) Listen to the recording. Try to remember the correct pronounciation of the cranial nerves then in pairs practise saying them. https://www.youtube.com/watch?v=0lbwshg_Kj4 58 READING 3.2.2 List of the cranial nerves (R) Study the list of the cranial nerves then cover the table and do the test below. The brain communicates with the body through the spinal cord and twelve pairs of cranial nerves. Ten of the twelve pairs of cranial nerves that control hearing, eye movement, facial sensations, taste, swallowing and movement of the face, neck, shoulder and tongue muscles originate in the brainstem. The cranial nerves for smell and vision originate in the cerebrum. Name I Olfactory II. Optic III - Oculomotor IV - Trochlear V - Trigeminal VI - Abducens VII - Facial VIII - Vestibulocochlear (Auditory) IX - Glossopharyngeal X - Vagus XI - Accessory XII - Hypoglossal Distribution Smell Vision Eyelid & eyeball movement Innervates superior oblique turns eye downward & laterally. Chewing, face & mouth touch & pain Turns eye laterally Controls most facial expression, Secretion of tears & saliva Taste Hearing, Equilibrium sensation Taste, Pharynx contraction Heart, lung and Viscera Contracts the neck and shoulder muscles Controls tongue movements http://www.mayfieldclinic.com/PE-AnatBrain.htm#.U8o7fPl_sgV 59 1. Which cranial nerve controls the following? 1) 2) 3) 4) Turns eye laterally _________________________ Vision _________________________ Heart, lung and viscera _________________________ Controls most facial expressions, secretion of tears, saliva, taste _________________________ 2. Find the pairs. 1) I - Olfactory 2) XI - Accessory 3) VIII - Vestibulocochlear 4) IX – Glossopharyngeal a) b) c) d) Contracts the neck and shoulder muscles Smell Taste, pharynx contraction Hearing, Equilibrium sensation 3. Choose the correct answer. 1. Innervates superior oblique turns eye downward & laterally. a) b) c) d) II – Optic VII – Facial IV – Trochlear V – Trigeminal 2. Controls tongue movements a) b) c) d) XII – Hypoglossal II – Optic X – Vagus VII – Facial 3. Eyelid & eyeball movement a) b) c) d) III – Oculomotor II – Optic XI – Accessory I – Olfactory 4. Chewing, face & mouth touch & pain a) b) c) d) VI – Abducens V – Trigeminal IV – Trochlear VII - Facial 60 4. True or False? 1. VII - Facial → Vision True False 2. IX - Glossopharyngeal → Taste, Pharynx contraction True False 3. V - Trigeminal → Chewing, Face & mouth touch & pain True False 4. I Olfactory → Contracts the neck and shoulder muscles True False www.quizlet.com VOCABULARY DEVELOPMENT 3.2.3 Scatter (V) Match the corresponding items. www.quizlet.com 61 3.3 SPINAL NERVES SPEAKING 3.3.1 Revision (S) With a partner discuss the following questions. 1) 2) 3) 4) 5) Name the five sections of the spine! How many vertebrae are in each of the sections? What are the functions of each section of the spine? What are the two functions of the intervertebral discs? Name the two types of bony process which protrude from each vertebra! READING 3.3.2 Spinal nerves (R) Complete the text with the missing prepositions from the box. on through Thirty-one pairs according to off of spinal nerves alongside down branch back across near from 1. __________the spinal cord. The spinal nerves act as “telephone lines,” carrying messages 2. __________ and forth between your body and spinal cord to control sensation and movement. Each spinal nerve has two roots. The ventral (front) root carries motor impulses 3. __________ the brain and the dorsal (back) root carries sensory impulses to the brain. The ventral and dorsal roots fuse together to form a spinal nerve, which travels 4. __________ the spinal canal, 5. __________ the cord, until it reaches its exit hole - the intervertebral foramen. Once the nerve passes 6. __________ the intervertebral foramen, it branches; each branch has both motor and sensory fibers. The smaller branch (called the posterior primary ramus) turns posteriorly to supply the skin and muscles of the back of the body. The larger branch (called the anterior primary ramus) turns anteriorly to supply the skin and muscles of the front of the body and forms most of the major nerves. 62 The spinal nerves are numbered 7. ___________ the vertebrae above which it exits the spinal canal. The 8 cervical spinal nerves are C1 through C8, the 12 thoracic spinal nerves are T1 through T12, the 5 lumbar spinal nerves are L1 through L5, and the 5 sacral spinal nerves are S1 through S5. There is 1 coccygeal nerve. The spinal nerves innervate specific areas and form a striped pattern 8. ___________ the body called dermatomes. Doctors use this pattern to diagnose the location of a spinal problem based 9. _________ the area of pain or muscle weakness. For example leg pain (sciatica) usually indicates a problem 10. __________ the L4-S3 nerves. A dermatome pattern shows which spinal nerves are responsible for sensory and motor control of specific areas of the body. http://www.mayfieldclinic.com/PE-AnatSpine.htm#.U-ytyvl_sgU 63 SPEAKING 3.3.3 Spinal Nerves - oral summary (S) In pairs answer the questions on the basis of the text above. 1) Name the roots of the spinal nerve. 2) What kind of impulses do they carry? 3) What is the spinal cord covered by? 4) How does the spinal nerve travel? 5) Where does it exit? What happens after this? 6) How are the spinal nerves numbered? 7) What does the word dermatome refer to? 8) What does the dermatome pattern show? VOCABULARY DEVELOPMENT 3.3.4 Coverings & spaces (V) 1. Match the words 1-5 with the definitions a-e. 1) 2) 3) 4) 5) _____ arachnoid mater _____ lumbar puncture _____ meninges _____ subarachnoid space _____ pia mater a) the three membranes that cover the brain and spinal cord (singular: meninx) b) one of the meninges, it is the delicate innermost membrane enveloping the brain and spinal cord. c) a delicate fibrous membrane forming the middle of the three coverings of the central nervous system d) the space between the arachnoidea and pia mater filled with cerebrospinal fluid e) it is a procedure whereby spinal fluid is removed from the spinal canal for the purpose of diagnostic 2. Complete the text with the words above. The spinal cord is covered with the same three membranes as the brain, called 1. ___________. The inner membrane is the 2. ___________, which is intimately attached to the cord. The next membrane is the 3. ___________. The outer membrane is the tough dura mater. Between these 64 membranes are spaces used in diagnostic and treatment procedures. The space between the pia and arachnoid mater is the wide 4. ____________, which surrounds the spinal cord and contains cerebrospinal fluid (CSF). This space is most often accessed when performing a 5. ___________ to sample and test CSF or during a myelogram to inject contrast dye. The space between the dura mater and the bone is the epidural space. This space is most often accessed to deliver anesthetic numbing agents, commonly called an epidural, and to inject steroid medication. 3.4 COMMON DISEASES OF THE CENTRAL NERVOUS SYSTEM SPEAKING 3.4.1 FAQS (S) With a partner, discuss the following questions. What does the term neurological disease refer to? What kind of common diseases of the central nervous system do you know? What are the symptoms of these diseases? How can you prevent nervous system diseases? Do you know any age related, stress related nervous system diseases? Are there any treatments for nervous system diseases? How are nervous system diseases diagnosed? Do you know any degenerative diseases? READING 3.4.2 Neurological diseases (R) Read the description of the following major types of neurological diseases (1-4) then decide which disease the people below are talking about (A-D). 1. Huntington's disease (HD) is an inherited disease that causes certain nerve cells in the brain to waste away. People are born with the defective gene, but symptoms usually don't appear until middle age. Early symptoms of HD may include uncontrolled movements, clumsiness, and balance problems. Later, HD can take away the ability to walk, talk, and swallow. Some people stop recognizing family members. Others are aware of their environment and are able to express emotions. If one of your parents has Huntington's disease, you have a 50 percent chance of getting it. A blood test can tell you if have the HD gene and will develop the disease. There is no cure. Medicines can help manage some of the symptoms, but cannot slow down or stop the disease. http://www.nlm.nih.gov/medlineplus/huntingtonsdisease.html 65 2. Stroke It is a medical emergency. Strokes happen when blood flow to your brain stops. Within minutes, brain cells begin to die. There are two kinds of stroke. The more common kind, called ischemic stroke, is caused by a blood clot that blocks or plugs a blood vessel in the brain. The other kind, called hemorrhagic stroke, is caused by a blood vessel that breaks and bleeds into the brain. "Ministrokes" or transient ischemic attacks (TIAs), occur when the blood supply to the brain is briefly interrupted. Symptoms of stroke are: sudden numbness or weakness of the face, arm or leg (especially on one side of the body) sudden confusion, trouble speaking or understanding speech sudden trouble seeing in one or both eyes sudden trouble walking, dizziness, loss of balance or coordination sudden severe headache with no known cause Acute stroke therapies try to stop a stroke while it is happening by quickly dissolving the blood clot or by stopping the bleeding. Post-stroke rehabilitation helps individuals overcome disabilities that result from stroke damage. Drug therapy with blood thinners is the most common treatment for stroke. http://www.ninds.nih.gov/disorders/stroke/stroke_backgrounder.htm 3. Epilepsy It is a brain disorder that causes people to have recurring seizures. The seizures happen when clusters of nerve cells, or neurons, in the brain send out the wrong signals. People may have strange sensations and emotions or behave strangely. They may have violent muscle spasms or lose consciousness. Epilepsy has many possible causes, including illness, brain injury, and abnormal brain development. In many cases, the cause is unknown. Doctors use brain scans and other tests to diagnose epilepsy. It is important to start treatment right away. There is no cure for epilepsy, but medicines can control seizures for most people. When medicines are not working well, surgery or implanted devices such as vagus nerve stimulators may help. Special diets can help some children with epilepsy. http://nanda-nurse-diary.blogspot.hu/2012/11/nursing-diagnosis-for-epilepsy.html http://www.nlm.nih.gov/medlineplus/epilepsy.html 66 4. Meningitis It is inflammation of the thin tissue that surrounds the brain and spinal cord, called the meninges. There are several types of meningitis. The most common is viral meningitis, which you get when a virus enters the body through the nose or mouth and travels to the brain. Bacterial meningitis is rare, but can be deadly. It usually starts with bacteria that cause a cold-like infection. It can block blood vessels in the brain and lead to stroke and brain damage. It can also harm other organs. Pneumococcal infections and meningococcal infections can cause bacterial meningitis. Anyone can get meningitis, but it is more common in people whose bodies have trouble fighting infections. Meningitis can progress rapidly. You should seek medical care quickly if you have a sudden fever a severe headache a stiff neck. Early treatment can help prevent serious problems, including death. Vaccines can prevent some of the bacterial infections that cause meningitis. Parents of adolescents and students living in college dorms should talk to a doctor about the vaccination. http://sehati.org/index/patientresources/normalanatomy.html http://www.nlm.nih.gov/medlineplus/meningitis.html A) ___________________________________ My father, 66, a wonderful man, on holiday with my mom woke up in the morning, complained of not being able to move his left side, my mom helped him out of bed, & he collapsed. The hotel immediately called 911, he was conscious on his way to the ER, but once there, they put him into a medically induced coma. They say that it was good that he remained conscious & was yelling my mom's name. But, the bleeding&swelling in his brain was so severe that the Dr. said if he was 10 years older they wouldn't have operated. They had to wait a day or two to perform surgery, I assume to allow some of the swelling to go down. They removed a large clot & felt they stopped most of the bleeding. Sarah http://www.stroke-survivors.co.uk/stroke-forum/messages.aspx?TopicID=305 67 B) ___________________________________ I guess when it really was noticeable was 2 1/2 years ago he was fired from working in the log woods cause his boss said he had become very clumsy and didn't have the reaction time he needed and he would just do stuff that was really dangerous that he knew better. He seemed to get worse but it was so slow that it became normal everyday until this year. He began in the summer to have just extreme sudden outburst of anger and would scream and yell and throw the biggest fits. It was very out of character for him. He became very aggressive and argumentive on a daily basis. He began accusing me of cheating on him to an extreme everyday. We would fight for days about it. Finally in July I couldn't take anymore. He was constantly yelling at me and putting me down and I told him if he didn't get some help I was leaving him. I made him an appt. and after talking to the neurologist we were sure he had this disease. Mary http://www.hdlf.org/phorum/read.php?5,83917 C) ___________________________________ Started with extreme hedache that was in the back of the head and neck. Headache was almost manageable with pinkillers but persisted. Pain then moved to excruciating pain in a wide band across lower back, up spine and neck and back of head, accompanied by nausea. No fever. Came to ER both times. Both times treated with intravenous Acyclovir. Pain managed by morphine and also given something for nausea. Worst syptoms over in 24 hours, feeling woozy for a week and less than perfect for a while- maybe a month or so. George http://www.patient.co.uk/forums/discuss/second-bout-of-viral-meningitis13218 68 D) ___________________________________ HI! I’m new to this forum but I’m desperate for help. I’ve been suffering with seizures or black outs since I was 5 years old. This has been happening on and off throughout my child hood. My first big and most violent seizure happened six months ago. I had numbness in the right side off my face, I couldn't stop shaking. I lost my ability to read and right for a short while too. However, my blood test and MRI came back all normal. However, for the last two months I’ve suffered with shaking (left hand) and painful headaches, and I’m tiered all the times. I can sleep for 20 hours or more. and I have trouble remembering things. Last week however I had like a twitch in my neck, and all off a sudden this passed through all my body (like tremors) and I passed out. I woke up in hospital. I had the same tests done again and they all come back normal. I still shake uncontrollably from my head to uper back non stop since, my head aches are getting worse. PLEASE IF ANYONE HAS HEARD OF OR SUFFER WITH SIMILAR SYMPTOMS PLEASE WRITE BACK, IM LOOSING CONTROL. Jessica http://www.patient.co.uk/forums/discuss/please-advise-134492 SPEAKING 3.4.3 Talking about common neurological diseases (S) With the help of the prompts speak about the following diseases. Huntington’s disease: cause, onset, symptoms, way of diagnosis, treatment Stroke: cause, types, „mini-stroke”, symptoms, therapy Epilepsy: cause, symptoms, diagnosis, treatment Meningitis: types of meningitis, symptoms, complications, treatment, prevention 69 WRITING 3.4.4 Seizure first Aid (W) What do you have to do for a person who has a seizure? Look at the pictures! What do they demonstrate? http://www.epilepsyheartland.org/Current/about%20epilepsy/aid.php WRITING 3.4.5 Questions about Epilepsy (W) 1. Can you think of any questions a patient with epilepsy can ask his/her doctor? Work in pairs. Collect your ideas. __________________________________________________________________________________ __________________________________________________________________________________ __________________________________________________________________________________ __________________________________________________________________________________ __________________________________________________________________________________ __________________________________________________________________________________ __________________________________________________________________________________ __________________________________________________________________________________ __________________________________________________________________________________ 70 2. You found the following article about epilepsy on the Internet. Read it and do the exercise below. What is the best first aid for a seizure? Here are some tips if you or someone you love has epilepsy. Always carry medical identification. If an emergency happens, knowledge of your seizure disorder can help the people around you keep you safe and provide the appropriate treatment. Make sure your family, friends, and co-workers know what to do if you have a seizure. Avoid potential dangers of high places or moving machinery at home, school, or work if you have active seizures. Though there is less risk if your seizures are under control, you should focus on the specific risks of certain activities (such as mowing, working around farm machinery, hot appliances, etc.). It is important for you to stay active, but you should choose your sports and other activities wisely. You may want to avoid contact sports, but if your seizures are well controlled, you can lead a normal life. The buddy system works well, so have another person with you who knows you have seizures and what to do if you have one. Activities such as baseball, bike riding, canoeing, horseback riding, or hockey can be made safer by wearing helmets and life jackets and by having another person with you -- but this is true for all people. If you take anticonvulsant medication, do not suddenly stop taking it or change the dosage without consulting your doctor. The type of anticonvulsant medication you are prescribed depends on the type of epilepsy you have, and the dose is determined by your weight, age, gender, and other factors. Be alert to the risks of possible drug interactions between your anticonvulsant drugs and other medications you may take, including over-the-counter drugs. Avoid alcohol, as it can interfere with the effectiveness of your medication and may lower the brain's seizure threshold. Doctors advise patients with seizures that they should not drive until their seizures are under control. This may be after six months or a year depending on the state. If a well-controlled person has a seizure after the doctor changes the medication, the patient may or may not be able to continue driving. What Should I Do for a Person Who Is Having a Seizure? If someone is having a seizure: Loosen clothing around the person's neck. Do not try to hold the person down or restrain them. This can result in injury. Do not insert any objects in the person's mouth. This can also cause injury. Reassure concerned bystanders who may be upset and ask them to give the person room. Remove sharp objects (glasses, furniture, and other objects) from around the person to prevent injury. After the seizure, it is helpful to lay the person on their side to maintain an open airway and prevent the person from inhaling any secretions. After a seizure, the person may be confused and should not be left alone. In many cases, especially if the person is known to have epilepsy, it is not necessary to call 911. Call 911 if the seizure lasts longer than 5 minutes, or if another seizure begins soon after the first, or if the person cannot be awakened after the movements have stopped. If you are concerned that 71 something else may be wrong, or the person has another medical condition such as heart disease or diabetes, you should contact a doctor immediately. http://www.webmd.com/epilepsy/guide/seizures-driving http://www.webmd.com/epilepsy/guide/first-aid-seizures 3. You got the following email from a patient with epilepsy on Epilepsy Forum UK. Answer it with the help of the text above. Dear Dr. Smith, I have epilepsy. It was diagnosed a month ago. I need urgent advice. I have so many questions. Could you please help me. I am so desparate. My questions are the following: What safety measures do I need to take at home or at work to prevent injuries when I have a seizure? Who else should know about my epilepsy? Is it okay for me to drive? Are there any sports activities that I should not do? Do I need to wear a helmet for any type of activities? Can I drink any alcohol with my medications? What should others do with me when I am having a seizure? After the seizure is over, what should they do? When should they call the doctor? When should we call 911? Thank you very much for your help in advance. Tom T. Dear Tom, ___________________________________________________________________________ ___________________________________________________________________________ ___________________________________________________________________________ ___________________________________________________________________________ ___________________________________________________________________________ ___________________________________________________________________________ ___________________________________________________________________________ 72 ___________________________________________________________________________ ___________________________________________________________________________ ___________________________________________________________________________ ___________________________________________________________________________ ___________________________________________________________________________ ___________________________________________________________________________ ___________________________________________________________________________ ___________________________________________________________________________ Regards Dr. Smith 3.5 OLD AGE AND ALZHEIMER’S DISEASE VOCABULARY DEVELOPMENT 3.5.1 Brainstorming – Old Age (V) What do you associate with old age? Collect and write down your ideas. Old Age SPEAKING 3.5.2 Caring for the elderly (S) 1. Think of an old person you know well or who stands close to you and answer the questions below. How healthy is he/she? Where does he/she live? Does he/she need help with daily tasks? If yes, with what? How does he/she keep mentally fit? 73 How does he/she keep physically fit? What worries him/her? How happy is he/she? 2. With a partner discuss the questions about care home. Would you like to live in a care home when you are old? Why/Why not? Make a list of advantages and disadvantages of a care home. + - 3. In small groups discuss how to have a happy, healthy and spiritually fulfilled old age? Present your ideas to the other groups. WRITING 3.5.3 Difficulties of the elderly (W) What difficulties do elderly people face? Use the words in the box, and write sentences. daily tasks food getting around shopping health recovery medication personal hygiene home __________________________________________________________________________________ __________________________________________________________________________________ __________________________________________________________________________________ __________________________________________________________________________________ __________________________________________________________________________________ __________________________________________________________________________________ __________________________________________________________________________________ __________________________________________________________________________________ __________________________________________________________________________________ 74 READING 3.5.4 Alzheimer’s disease facts (R) Read the text and decide if the following statements are true (T) or false (F). http://www.medindia.net/patients/patientinfo/infographic s-on-Alzheimers.htm 1) Memory loss is a symptom of Alzheimer’s disease. _____ 2) Alzheimer’s disease can appear before the age of 65. _____ 3) As Alzheimer’s disease is a progressive disease, symptoms get better over time. _____ 4) In its late stage, patients are not able to communicate any more. _____ 5) After the symptoms are noticed, Alzheimer’s patients survive 4-8 years. _____ 6) There is no medicine available which can cure Alzheimer’s. ____ Alzheimer's is the most common form of dementia, a general term for memory loss and other intellectual abilities serious enough to interfere with daily life. The majority of people with Alzheimer's are 65 and older. But Alzheimer's is not just a disease of old age. Up to 5 percent of people with the disease have early onset Alzheimer's (also known as younger-onset), which often appears when someone is in their 40s or 50s. Alzheimer's worsens over time. Alzheimer's is a progressive disease, where dementia symptoms gradually worsen over a number of years. In its early stages, memory loss is mild, but with late-stage Alzheimer's, individuals lose the ability to carry on a conversation and respond to their environment. Alzheimer's is the sixth leading cause of death in the United States. Those with Alzheimer's live an average of eight years after their symptoms become noticeable to others, but survival can range from four to 20 years. Alzheimer's has no current cure, but treatments for symptoms are available and research continues. Although current Alzheimer's treatments cannot stop Alzheimer's from progressing, they can temporarily slow the worsening of dementia symptoms and improve quality of life for those with Alzheimer's and their caregivers. http://www.alz.org/alzheimers_disease_what_is_alzheimers.asp 75 2. Find the words from the text with these meanings. 1) a serious mental disorder caused by brain disease or injury, that affects the ability to think, remember and behave normally _______________ 2) the beginning of something, especially something unpleasant _______________ 3) happening or developing steadily _______________ 4) to become or make something worse than it was before _______________ 5) slowly, over a long period of time _______________ 6) to give a spoken or written answer to somebody/something _______________ 7) a person who takes care of a sick or old person at home _______________ LISTENING 3.5.5 Stages of Alzheimer’s (L) How many stages does Alzheimer’s have? Listen to the recording and write down the part of the brain that Alzheimer’s affects and the damage it does to it. Source: https://www.youtube.com/watch?v=7_kO6c2NfmE STAGES PART OF THE BRAIN AFFECTED/DAMAGE 1. 2. 3. 4. 5. 6. 7. 76 SPEAKING 3.5.6 Doctor-patient conversation (S) With a partner, act out the roles below. Student A: Your grandfather has been diagnosed with Alzheimer’s. You do not know much about the disease. Consult your doctor about: the disease itself the stage your grandfather is at medication treatment suggestions (As you are mother of 3 you cannot supervise your grandfather in 24 hours) Student B: You are a doctor. One of your Alzheimer’s patient’s relative ask you about: the diseases itself the stage your grandfather is at (stage 2.) medication (no cure, but slows down down the progression) treatment suggestions (need for long-term care, assisted living, nursing home) 77 3.6 THE PERIPHERAL NERVOUS SYSTEM VOCABULARY DEVELOPMENT 3.6.1 The peripheral nervous system – Key points (V) Read the text about the peripheral nervous system then do the exercise below. https://www.boundless.com/image/the-nervous-system/ 78 The peripheral system connects the central nervous system to the rest of the body. The main divisions of the PNS are: The autonomic nervous system — which controls the automatic functions of the body: the heart, smooth muscle (organs) and glands. It is divided into the “fight-or-flight” system (sympathetic nervous system) and the “resting and digesting" system (parasympathetic nervous system). The somatic nervous system — which allows us to consciously or voluntarily control our skeletal muscles. The somatic system contains 12 cranial nerves and 31 spinal nerves. https://www.boundless.com/psychology/the-brain-and-behavior/the-nervous-system/the-peripheral-nervoussystem-pns/ Match the terms with the definitions. 1) 2) 3) 4) 5) 6) Neurons Nerve impulses Neurotransmitters Dendrites Axons Synapse Chemicals released by one neuron to excite a neighbouring one Messenger cells in your nervous system Fibres that carry information away from it, called axons Fibres that carry information towards the cell body Electrical signals carrying messages The point at which a nervous impulse passes from one neuron to another READING 3.6.2 The neuron (R) Read the text then locate and identify the structures of a neuron. dendrite cell body axon dendrite, cell body, axon 79 http://lrrpublic.cli.det.nsw.edu.au/lrrSecure/Sites/LRRView/7700/documents/5657/5657/applets/neuronesdn d.html Nerves which are made up of special cells called neurons. Neurons are comprised of a dendrite, a cell body and an axon. Impulses travel to the dendrite into the cell body and then onto the axon. A special sheath called myelin, which increases the conductivity of the neuron, covers some nerves. As messages travel from one neuron to the next they move across a synapse. At each synapse there is a chemical releases called a neurotransmitter. At various parts of the body specific neurotransmitters facilitate communication, for example dopamine (motor function), serotonin (mood) and endorphins (painkillers). Sensory neurons carry messages from a receptor to the brain. The brain then interprets the message. Motor neurons then send the message to an affector in muscles and glands. Receptor (sensory organ) sends a signal to the sensory neuron which sends a signal to the brain/spinal chord which sends a signal to the motor neuron which sends a signal to the affector (muscle/gland). http://www.bbc.co.uk/science/humanbody/body/factfiles/nervecellsandnerves/nerve_cells_and_nerves.shtml https://www.boundless.com/psychology/the-brain-and-behavior/the-nervous-system/the-peripheral-nervous-system-pns/ 2. What are the differences between the axons and the dendrites? Put the number of each feature to the correct place in the table. 1) 2) 3) 4) 5) 6) 7) 8) 9) 10) 11) 12) Take information away from the cell body Have a rough surface Many dendrites per cell No myelin Branch far from the cell body No ribosome Only one axon per cell Bring information to the cell body Have ribosome Branch near the cell body Have myelin Have a smooth surface Axons Dendrites http://www.gwinnett.k12.ga.us/LilburnES/PromoteGA/biochemistry/Neuron_a_and_d.html 80 SPEAKING 3.6.3 Parts of the PNS (S) In your own words speak about the following parts of the PNS. sympathetic nervous system parasymphatetic nervous system somatic nervous system autonomic nervous system 3.7 MENTAL DISEASES READING 3.7.1 What is mental illness? (R) 1. With a partner discuss, who is mentally ill. A person is mentally ill, if …… 2. Read the text about mental illnesses then do the task below. A mental illness is a medical condition that disrupts a person's thinking, feeling, mood, ability to relate to others and daily functioning. Just as diabetes is a disorder of the pancreas, mental illnesses are medical conditions that often result in a diminished capacity for coping with the ordinary demands of life. Serious mental illnesses include major depression, schizophrenia, bipolar disorder, obsessive compulsive disorder (OCD), panic disorder, posttraumatic stress disorder (PTSD) and borderline personality disorder. The good news about mental illness is that recovery is possible. Mental illnesses can affect persons of any age, race, religion or income. Mental illnesses are not the result of personal weakness, lack of character or poor upbringing. Mental illnesses are treatable. Most people diagnosed with a serious mental illness can experience relief from their symptoms by actively participating in an individual treatment plan. http://www.nami.org/Template.cfm?Section=By_Illness 81 2. Which of these people do you think may have a mental illness? Discuss each one with your partner. a. Stephen Gough (born c. 1959), also known as Steve Gough and the Naked Rambler, is an activist, and a British former Royal Marine. In 2003-2004, he walked the length of Great Britain naked. He did it again in 2005-2006, but was arrested in England and in Scotland. He subsequently spent six years in prison, having been repeatedly rearrested for public nudity within a short period, each time he was released. http://en.wikipedia.org/wiki/Stephen_Gough b. By the time Susan Smith goes to bed, she will have cleaned the house over 10 times a day. She doesn’t feel good when she cleans the house once but instead she finds herself continuously repeating the same task over and over. http://www.helpguide.org/mental/obsessive_compulsive_disorder_ocd.htm c. John Davis has difficulty sustaining attention in academic or work tasks and activities. He is often bored and indifferent. He does not pick up on other people’s mood, feelings (e.g., may say the wrong thing at the wrong time). He has extreme mood swings, irritability or a persistently depressed mood. http://www.nesca-news.com/2013/09/your-teenagers-behavior-what-to-expect.html d. Jeniffer Parkson thinks she is in danger and that is why she does not leave her home. She believes that other people are trying to harm her. She doubts the commitment, loyalty, or trustworthiness of others, believing others are using or deceiving her. http://www.webmd.com/mental-health/paranoid-personality-disorder 82 e. Andy Park, 43, known as Mr Christmas, has celebrated Christmas every day for 15 years. Every day since 1993 the divorced electrician has breakfasted on mince pies and sherry, before opening the presents he has bought for himself. Then he eats a full roast turkey lunch and watches the Queen's Speech on video. http://www.dailymail.co.uk/news/article-506249/Mr-Christmas-The-man-celebrated-festive-season-365days-year--15-years.html f. When John Taylor gets into his car, he becomes a real monster. He makes rude gestures, verbal insults, he drives in an unsafe or threatening manner. http://en.wikipedia.org/wiki/Road_rage VOCABULARY DEVELOPMENT 3.7.2 Symptoms (V) Match the words (1-10) with the definitions (a-j). Write your answers in the chart below. 1. hallucination 2. paranoia 3. mania 4. delusion 5. disoriented 6. anxiety 7. euphoria 8. mood 9. malingering 10. echolalia a. the state of feeling nervous or worried that something bad is going to happen b. an extremely strong feeling of happiness and excitement that usually lasts only a short time c. to pretend to be ill/sick, especially in order to avoid work d. the way you are feeling at a particular time e. feeling confused f. something that is seen or heard when it is not really there g. a false belief or opinion about yourself or your situation h. the act of repeating everything somebody says, as a result of a mental disorder i. a person may wrongly believe that other people are trying to harm them, that they are somebody very important, etc. j. somebody has an obsession about something that makes them extremely anxious, violent or confused 83 http://www.oxfordlearnersdictionaries.com/definition/english/landmark 1 2 3 4 5 6 7 8 9 10 READING 3.7.3 Common mental illnesses (R) Which disease is described below? Match the names 1-6 with the explanations A-F. 1. 2. 3. 4. 5. 6. Bipolar disorder Obsessive-compulsive disorder Panic disorder Major depression Borderline Personality Disorder Schizophrenia A. ______________________________ It is a mood state that goes well beyond temporarily feeling sad or blue. It affects one’s thoughts, feelings, behavior, mood and physical health. It is a life-long condition in which periods of wellness alternate with recurrences of illness. It involves some combination of the following symptoms: depressed mood (sadness), poor concentration, insomnia, fatigue, appetite disturbances, excessive guilt and thoughts of suicide. Left untreated, it can lead to serious impairment in daily functioning and even suicide. http://www.nami.org/template.cfm?section=Depression B. ________________________________ It is a serious mental illness. It most often appears in men in their late teens or early twenties, while it appears in women in their late twenties or early thirties. Interfering with a person's ability to think clearly, manage emotions, make decisions and relate to others, it impairs a person's ability to function to their potential when it is not treated, because the illness may cause unusual, inappropriate and sometimes unpredictable and disorganized behavior. The apparent erratic behavior is often caused by the delusions and hallucinations that are symptoms of this condition. http://www.nami.org/Template.cfm?Section=schizophrenia9 84 C. ________________________________ It is a chronic illness with recurring episodes of mania and depression that can last from one day to months. It causes unusual and dramatic shifts in mood, energy and the ability to think clearly. Cycles of high (manic) and low (depressive) moods may follow an irregular pattern that differs from the typical ups and downs experienced by most people. The symptoms of this disorder can have a negative impact on a person’s life. Damaged relationships or a decline in job or school performance are potential effects, but positive outcomes are possible. http://www.nami.org/Content/NavigationMenu/Mental_Illnesses/Bipolar1/Home_-_What_is_Bipolar_Disorder_.htm D. _______________________________ It is an anxiety disorder characterized by uncontrollable, unwanted thoughts and repetitive, ritualized behaviors you feel compelled to perform. If you have this condition, you probably recognize that your obsessive thoughts and compulsive behaviors are irrational – but even so, you feel unable to resist them and break free. It causes the brain to get stuck on a particular thought or urge. http://www.nami.org/Template.cfm?Section=By_Illness&Template=/ContentManagement/ContentDisplay.cfm&ContentID=142546 E. _______________________________ It is an uncontrollable and terrifying response to ordinary, nonthreatening situations. People have recurrent panic attacks, persistent anxiety or fear regarding their panic attacks and change their behavior in an attempt to avoid further panic attacks. Individuals with this disease are likely to experience some combination of the following symptoms during a panic attack: sweating, hot or cold flashes, choking or smothering sensations, racing heart, labored breathing, trembling, chest pains, faintness, numbness, nausea or disorientation. They may feel like they are dying, losing control or losing their mind. http://www.nami.org/Template.cfm?Section=By_Illness&Template=/ContentManagement/ContentDisplay.cfm&ContentID=23050 F. ______________________________ It is a mental illness that causes intense mood swings, impulsive behaviors, and severe problems with self-worth. It can lead to troubled relationships in every area of a person's life. Most of the time, signs of the disorder first appear in childhood. But problems often don't start until early adulthood. The most common symptoms include: Harmful, impulsive behaviors. These may include things like substance abuse, binge eating, out-of-control spending, risky sexual behavior, and reckless driving. Relationship problems. You may see others as either "good" or "bad" and may shift from one view to the other suddenly, for minor reasons. Low self-worth. A frantic fear of being left alone (abandoned). 85 Aggressive behavior. Hurting yourself, such as cutting or burning yourself. http://www.nami.org/Template.cfm?Section=By_Illness&Template=/ContentManagement/ContentDisplay.cfm&ContentID=44780 READING 3.7.4 Tourette syndrome (R) Read the text about Tourette syndrome and answer the questions! 1. What are the typical features of the disease? 2. Where does its name come from? 3. When does Tourette syndrome first appear? 4. When are the worst tics experienced? 5. What makes the symptoms worse? 6. Can tics be controlled? 7. What other problems may people with Tourette syndrome have? Tourette syndrome (TS) is a neurological disorder characterized by repetitive, stereotyped, involuntary movements and vocalizations called tics. The disorder is named for Dr. Georges Gilles de la Tourette, the pioneering French neurologist who in 1885 first described the condition in an 86year-old French noblewoman. The early symptoms of TS are typically noticed first in childhood, with the average onset between the ages of 3 and 9 years. TS occurs in people from all ethnic groups; males are affected about three to four times more often than females. It is estimated that 200,000 Americans have the most severe form of TS, and as many as one in 100 exhibit milder and less complex symptoms such as chronic motor or vocal tics. Although TS can be a chronic condition with symptoms lasting a lifetime, most people with the condition experience their worst tic symptoms in their early teens, with improvement occurring in the late teens and continuing into adulthood. Motor and vocal tics are classified as either simple or complex. Tics are often worse with excitement or anxiety and better during calm, focused activities. Certain physical experiences can trigger or worsen tics, for example tight collars may trigger neck tics, or hearing another person sniff or throatclear may trigger similar sounds. Tics do not go away during sleep but are often significantly diminished. Although the symptoms of TS are involuntary, some people can sometimes suppress, or otherwise manage their tics in an effort to minimize their impact on functioning. However, people with TS often report a substantial buildup in tension when suppressing their tics to the point where they feel that the tic must be expressed (against their will). Tics in response to an environmental trigger can appear to be voluntary or purposeful but are not. 86 Many individuals with TS experience additional neurobehavioral problems that often cause more impairment than the tics themselves. These include inattention, hyperactivity and impulsivity (attention deficit hyperactivity disorder—ADHD); problems with reading, writing, and arithmetic; and obsessive-compulsive symptoms such as intrusive thoughts/worries and repetitive behaviors. http://www.nami.org/Template.cfm?Section=By_Illness&Template=/ContentManagement/ContentDisplay.cfm &ContentID=23053 VOCABULARY DEVELOPMENT 3.7.5 List of tics (V) This is a list of some tics. Decide which one is a motor (write M) or a vocal (write V) tic. motor tics = short-lasting sudden movements vocal tics = short-lasting uttered sounds Tics clapping kicking muttering spitting hiccupping swearing blinking chewing clothes licking things offensive gestures somersaulting M/V Tics belching stuttering shivering shouting sniffing throwing things sticking out the tongue making faces scratching smelling things frowning M/V http://www.tourette-london.ca/ae0016.htm LISTENING 3.7.6 Seasonal Affective Disorder (L) Listen to the following text on Seasonal Affective Disorder and decide if the following statements are true (write T) or false (write F)! Source: https://www.youtube.com/watch?v=JP7T2q3yeUM 1. In autumn when days get shorter people may experience seasonal depression. 2. The main symptoms are high energy and bad mood, sadness, lethargy, apathy. 3. 10-15% of Canadian people suffer from a severe form of seasonal affective disorder. 87 4. Those who have the ’winter blues’ feel that winter is a terrible time and they want to stay at home. 5. There are more women than man suffering from seasonal affective disorder. 6. Light therapy is the least commonly used type of treatment option for this condition. 7. Exposure to natural light can be very effective to treat winter mood changes if it is feasible. 8. Doing sport is not considered a preventative or maintenance treatment if patients are better. 9. Seasonal depression can be linked with the obesity epidemic. 10. It is better to see a doctor, if you experience signs of depression at this time of the year. SPEAKING 3.7.7 Stigma of Mental Illnesses (S) 1. Do you know these people? What is common in all of them? http://www.health.com/health/gallery/0,,20526304_6,00.html http://www.health.com/health/gallery/0,,20526304_9,00.html http://www.health.com/health/gallery/0,,20526304_15,00.html 2. In small groups discuss the questions below. 1. What is mental health stigma? 2. Why are people with mental illness stigmatized? 3. What kinds of characteristics are attributed to a person with mental illness? 88 4. How can people who are stigmatized feel? 5. Can famous people help remove this stigma of mental illness? 6. Are there any psychiatric illnesses in your country which are stigmatized? 7. Are public attitudes changing or have they been the same for a long time? 8. How would you change people’s opinion to look at mental illnesses in a more positive way as a health care professional? http://apt.rcpsych.org/content/6/1/65.full 89 3.8 VOCABULARY abducens nerve amygdala anticonvulsant anulus arachnoid mater atlas autonomic nervous system axon basal ganglion - ganglia brain stem bundle cartilage caudate cerebellum cerebralcerebrospinal fluid (CSF) cerebrum cervical cervix cingulate gyri circadian rythm clumsiness coccygeal coccyx compromise corpus callosum cortex cranial nerve cushion dendrite dermatome dorsal (back) root dura mater endocrine facial nerve frontal lobe ganglion/ganglia globus pallidus glossopharyngeal nerve gray matter/substance gyrus hemisphere hemorrhagic stroke hippocampus hypoglossal nerve hypothalamus szemtávolító ideg amygdala (a szociabilitásért felelős agyi terület) görcsoldó körgyűrű pókhálóhártya atlascsigolya vegetatív, autonóm idegrendszer efferens nyúlvány bazális ganglion agytörzs köteg porc farok kisagy agy gerincfolyadék agy nyaki nyak gyrus cinguli, övtekervény napi ritmus ügyetlenség, balkezesség farokcsonti farokcsont veszélyeztet kérgestest kéreg agyi ideg kipárnáz, beágyaz afferens nyúlvány bőrszelvény, dermatoma dorsális gyökér kemény agyhártya belső elválasztású, endokrin arcideg homloklebeny idegdúc, központ globus pallidus/pallidum nyelv- és garatideg szürkeállomány agytekervény agyélteke haemorrhagiás stroke (vérzéssel járó) hippocampus nyelv alatti ideg hipotalmusz 90 iliac innervate interpretative intervertebral disc intervertebral foramen ischemic stroke limbic system lumbar lumbar puncture mastication medulla oblongata melatonin meninges meningitis meninx motor nerve motor neurone myelin myelin sheath myelogram nerve root neuron neurotransmitter node nucleus - nuclei nucleus pulposus nucleus/nuclei oblique muscle occipital lobe occipital lobe oculomotor nerve odontoid olfactory nerve optic nerve parasymphatetic nervous system parietal lobe pedicle peg pia mater pineal gland pituitary gland plaque plexus pons process putamen reabsorb rear csípőstimulál értelmező porckorong csigolyák közötti nyílás, foramen intervertebrale ischaemiás stroke limbikus rendszer ágyéki lumbálpunkció, gerinccsapolás rágás nyúltagy, nyúltvelő melatonin agyhártyák agyhártyagyulladás agyhártya mozgató ideg mozgató sejt mielin, velő, (Schwannsejtek hártyájának anyaga mielinhüvely, idegrostot körülvevő védőburok csontvelő sejtjeinek megoszlása ideggyök idegsejt neurotranszmitter csomó sejtmag csigolák kozti lemezek rostos porcos központja sejtmag ferde hasizom tarkólebeny nyakszirti lebeny szemmozgató ideg fog alakú szaglóideg látóideg paraszimpatikus idegrendszer fali lebeny kocsány ék lágy agyhártya tobozmirigy hipofízis plakk idegfonat pons, híd nyúlvány belső hártya elnyel hátsó része valaminek 91 ribosome sacral sacrum sciatica seizure somatic nervous system spasm spinal accessory nerve spinal cord spinal nerve spinous process subarachnoid space sulcus symphatetic nervous system synapse temporal lobe thoracic transient ischemic attacks transient transverse process trigeminal nerve trochlear nerve vagus/vagi ventral root ventricle vertigo vestibulocochlear nerve viscera visceral waste away white matter/substance wreak havoc riboszóma keresztcsonti keresztcsont ischias syndroma roham szomatikus idegrendszer görcs járulékos ideg gerincvelő gerincvelői ideg csigolya-tövisnyúlvány, processus spinosus subarachnoidalis tér agybarázda szimpatikus idegrendszer szinapszis halántéklebeny mellkasi tranziens ischaemiás attack átmeneti, múló, tranziens csigolya-harántnyúlvány, processus transversus háromosztatú ideg sodorideg bolygóideg ventrális gyökér agykamra szédülés egyensúly- és hallóideg zsiger zsigeri elsorvad fehérállomány elpusztít 92 UNIT 4. RESPIRATORY SYSTEM Aims of the Unit In this unit you will learn about: the anatomy of the respiratory system, muscles of respiration, physiology of the respiratory system and diseases of the respiratory system such as lung cancer, COPD, asthma etc. 93 4.1 ANATOMY OF THE RESPIRATORY SYSTEM LISTENING 4.1.1 Introduction to the Respiratory System (L) Listen to recording about the respiratory system and complete the text with the missing words. Then watch the video. Source: https://www.youtube.com/watch?v=o2OcGgJbiUk The respiratory system moves air through the nose, pharynx, larynx, trachea and bronchus to the alveoli where the gas exchange between oxygen and carbon dioxide occurs. 1. ____________ are the openings to the nose. The nasal cavity is lined with 2. ___________, mucous membranes and blood capillaries. The air is filtered by cilia, 3. __________ by mucous membranes and warmed by the blood. Air moves into the pharynx or throat, the common passageway for food and air. Air continues on to the larynx. The epiglottis, a 4. ____________ of tissue in front of the larynx, closes off the larynx when swallowing to prevent food from entering. The larynx or voice box contains the 5. ___________ __________. The trachea or windpipe connects the larynx to the 6. __________ __________. The cartilage rings of the trachea prevent the trachea from collapsing. Lungs are spongy tissue with alveoli and blood capillaries. Breathing occurs because of the expansion and 7. ___________ of the lungs. The bronchi carrying the air subdivide into smaller branches called 8. __________. At the end of each bronchiole are the alveolar sacs. The alveolar sacs are surrounded by blood capillaries and contain millions of single layer 9. __________ __________ where the gas exchange takes place. Oxygenated air goes through the nose to the pharynx, larynx, trachea, bronchus and alveoli. By the process of the fusion, oxygen in the air moves from the alveoli to the capillaries. Carbon dioxide moves from the capillaries into the alveoli and is 10. ___________. This process is called respiration. There are 3 major parts of the respiratory system: the airway, the lungs, and the muscles of respiration. The airway, which includes the nose, mouth, pharynx, larynx, trachea, bronchi, and bronchioles, carries air between the lungs and the body’s 11. ___________ . The lungs act as the functional units of the respiratory system by passing oxygen into the body and carbon dioxide out of the body. Finally, the muscles of respiration, including the diaphragm and intercostal muscles, work together to act as a 12. ___________, pushing air into and out of the lungs during breathing. http://users.rcn.com/jkimball.ma.ultranet/BiologyPages/P/Pulmonary.html 94 READING 4.1.2 Organs of the respiratory system (R) Write the letter of the most suitable sentence (1-8) in the text below. There is one extra sentence, which you do not need. 1) 2) 3) 4) 5) 6) 7) 8) the structure of the walls of the airway begins to change due to the heart pointing to the left side of the body allow it to remain open to air at all times but the oral cavity can be used to supplement or replace the nasal cavity’s functions which is often referred to as the Adam’s apple the sinuses provide resonance for the voice to warm, moisturize, and filter air entering the body before it reaches the lungs that acts as a switch between the trachea and the esophagus Nose and Nasal Cavity The nose is a structure of the face made of cartilage, bone, muscle, and skin that supports and protects the anterior portion of the nasal cavity. The nasal cavity is a hollow space within the nose and skull that is lined with hairs and mucus membrane. The function of the nasal cavity is 1. ________________________________ . Hairs and mucous lining the nasal cavity help to trap dust, mold, pollen and other environmental contaminants before they can reach the inner portions of the body. Air exiting the body through the nose returns moisture and heat to the nasal cavity before being exhaled into the environment. http://www.naturalhealthschool.com/nose_sinuses.html Mouth The mouth, also known as the oral cavity, is the secondary external opening for the respiratory tract. Most normal breathing takes place through the nasal cavity, 2. ________________________________ when needed. Because the pathway of air entering the body from the mouth is shorter than the pathway for air entering from the nose, the mouth does not 95 warm and moisturize the air entering the lungs as well as the nose performs this function. The mouth also lacks the hairs and sticky mucus that filter air passing through the nasal cavity. Pharynx The pharynx is a muscular funnel that extends from the posterior end of the nasal cavity to the superior end of the esophagus and larynx. The pharynx is divided into 3 regions: the nasopharynx, oropharynx, and laryngopharynx. The epiglottis is a flap of elastic cartilage 3. ________________________________ . Because the pharynx is also used to swallow food, the epiglottis ensures that air passes into the trachea by covering the opening to the esophagus. During the process of swallowing, the epiglottis moves to cover the trachea to ensure that food enters the esophagus and to prevent choking. http://en.wikipedia.org/wiki/Pharynx Larynx The larynx is a short section of the airway that connects the laryngopharynx and the trachea. The larynx is located in the anterior portion of the neck, just inferior to the hyoid bone and superior to the trachea. Several cartilage structures make up the larynx and give it its structure. Inferior to the epiglottis is the thyroid cartilage, 4. ________________________________ as it is most commonly enlarged and visible in adult males. The thyroid holds open the anterior end of the larynx and protects the vocal folds. Inferior to the thyroid cartilage is the ring-shaped cricoid cartilage which holds the larynx open and supports its posterior end. In addition to cartilage, the larynx contains special structures known as vocal folds, which allow the body to produce the sounds of speech and singing. The vocal folds are folds of mucous membrane that vibrate to produce vocal sounds. Trachea The trachea is a 5-inch long tube made of C-shaped hyaline cartilage rings. The trachea connects the larynx to the bronchi and allows air to pass through the neck and into the thorax. The rings of cartilage making up the trachea 5. ________________________________. The main function of the trachea is to provide a clear airway for air to enter and exit the lungs. In addition, the epithelium lining the trachea produces mucus that traps dust and other contaminants and prevents it from reaching the lungs. Cilia on the surface of the epithelial cells move the mucus superiorly toward the pharynx where it can be swallowed and digested in the gastrointestinal tract. 96 http://www.webmd.com/lung/picture-of-the-trachea Bronchi and Bronchioles At the inferior end of the trachea, the airway splits into left and right branches known as the primary bronchi. The left and right bronchi run into each lung before branching off into smaller secondary bronchi. The secondary bronchi carry air into the lobes of the lungs - 2 in the left lung and 3 in the right lung. The secondary bronchi in turn split into many smaller tertiary bronchi within each lobe. The tertiary bronchi split into many smaller bronchioles that spread throughout the lungs. Each bronchiole further splits into many smaller branches less than a millimeter in diameter called terminal bronchioles. Finally, the millions of tiny terminal bronchioles conduct air to the alveoli of the lungs. As the airway splits into the tree-like branches of the bronchi and bronchioles, 6. ______________________________. The primary bronchi contain many C-shaped cartilage rings that firmly hold the airway open and give the bronchi a cross-sectional shape like a flattened circle or a letter D. As the bronchi branch into secondary and tertiary bronchi, the cartilage becomes more widely spaced and more smooth muscle and elastin protein is found in the walls. The main function of the bronchi and bronchioles is to carry air from the trachea into the lungs. http://www.nytimes.com/health/guides/disease/asthma/print.html 97 Lungs The lungs are a pair of large, spongy organs found in the thorax lateral to the heart and superior to the diaphragm. Each lung is surrounded by a pleural membrane that provides the lung with space to expand as well as a negative pressure space relative to the body’s exterior. The negative pressure allows the lungs to passively fill with air as they relax. The left and right lungs are slightly different in size and shape 7. ______________________________. The left lung is therefore slightly smaller than the right lung and is made up of 2 lobes while the right lung has 3 lobes. The interior of the lungs is made up of spongy tissues. The alveoli are cup-shaped structures found at the end of the terminal bronchioles and surrounded by capillaries. The alveoli are lined with thin simple squamous epithelium that allows air entering the alveoli to exchange its gases with the blood passing through the capillaries. http://www.innerbody.com/anatomy/respiratory http://www.abc.net.au/health/library/stories/2010/07/29/2967396.htm WRITING 4.1.3 Summary of the Respiratory System (W) Complete the summary of respiratory system with the help of the text above. Then talk about it in your own words. 1) The nasal cavity is lined with ______________________________________. 2) The functions of the nasal cavity ______________________________________. 3) The pathway of air from the mouth to the lung ____________________________________ and as opposed to the nose ______________________________________. 4) The mouth also lacks the hairs and sticky mucus that ________________________________. 5) The pharynx is divided into 3 regions: ______________________________________. 6) The epiglottis is ______________________________________. 7) The larynx connects ______________________________________. 8) Vocal folds are special structures within the larynx, which ____________________________. 98 9) The trachea connects the larynx to the bronchi and its main function is _________________. 10) Furthermore, the epithelium lining the trachea produces mucus that ___________________. 11) The trachea splits into left and right branches, the primary bronchi. The left and right bronchi branch off into smaller secondary bronchi. The secondary bronchi in turn split into many smaller tertiary bronchi within each lobe. The tertiary bronchi split _____________________ and further splits into ______________________________________. Finally, ___________. 12) The lung is made up ______________________________________. 13) The interior of the lungs is made up of spongy tissues containing ______________________. VOCABULARY DEVELOPMENT 4.1.4 Medical terms vs. common English names about the respiratory system (V) Match the medical terms and common English names about the respiratory system. A B 1) 2) 3) 4) 5) 6) 7) 8) nasal cavity oral cavity trachea pharynx larynx thyroid cartilage thorax pulmonary a) b) c) d) e) f) g) h) mouth throat Adam’s apple nose chest lung windpipe voice box 2. Work in pairs. Student A reads out the description in Column A for Student B. Student B has to find out which word is meant. The solutions can be found in the Answer Key. Student B reads out the description in Column B for Student A. Student A has to find out which word is meant. The solutions can be found in the Answer Key. One correct answer is worth one score. The one who has more scores is the winner. Column A 1. LINED WITH MUCOUS MEMBRANE AND FINE HAIRS. IT ACTS LIKE A FILTER TO MOISTEN AND WARM THE ENTERING AIR. 2. PARTITION SEPARATING THE RIGHT AND LEFT NASAL CAVITIES. 99 3. SERVES AS FOOD AND AIR PASSAGEWAY. AIR ENTERS FROM THE NASAL CAVITIES AND PASSES THROUGH THE PHARYNX TO THE LARYNX. FOOD ENTERS THE PHARYNX FROM THE MOUTH AND PASSES INTO THE ESOPHAGUS. 4. LYMPHOID TISSUE LOCATED BEHIND THE MOUTH. 5. LOCATION OF THE VOCAL CORDS. AIR ENTERS FROM THE PHARYNX (VOICE BOX). 6. FLAP OF CARTILAGE THAT AUTOMATICALLY COVERS THE OPENING OF AND KEEPS FOOD FROM ENTERING THE LARYNX DURING SWALLOWING. 7. ONE OF TWO BRNACHES FROM THE TRACHEA THAT CONDUCTS AIR INTO THE LUNGS, WHERE IT DIVIDES AND SUBDIVIDES. THE BRANCHINGS RESEMBLE A TREE; THEREFORE, THEY ARE REFERRED TO AS A BROCHIAL TREE. Column B 1. SMALLEST SUBDIVISION OF THE BRONCHIAL TREE. 2. AIR SACS AT THE END OF THE BRONCHIOLES. OXYGEN AND CARBON DIOXIDE ARE EXCHANGED THROUGH THE ALVEOLAR WALLS AND THE CAPILLARIES. 3. TWO SPONGE LIKE ORGANS IN THE THORACIC CAVITY. THE RIGHT LUNG CONSISTS OF THREE LOBES, AND THE LEFT LUNG HAS TWO LOBES. 4. DOUBLE-FOLDED SEROUS MEMBRANE COVERING EACH LUNG AND LINING THE THORACIC CAVITY WITH A SMALL SPACE BETWEEN, CALLED THE PLEURAL CAVITY, WHICH CONTAINS SEROUS FLUID. 5. MUSCULAR PARTITION THAT SEPARATES THE THORACIC CAVITY FROM THE ABDOMINAL CAVITY. IT AIDS IN THE BREATHING PROCESS BY CONTRACTING AND PULLING AIR IN, THEN RELAXING AND PUSHING AIR OUT. 6. PASSAGEWAY FOR AIR TO THE BRONCHI 7. THE LARGEST CARTILAGE OF THE LARYNX, HAVING TWO BROAD PROCESSES THAT JOIN ANTERIORLY TO FORM THE ADAM’S APPLE http://www.cram.com/flashcards/2010-respiratory-therapist-kaplan-medical-terminology-organs-of-therespiratory-system-chapter-5-1263039 SPEAKING 4.1.5 Identifying and speaking about the structures of the respiratory system (S) Identify the structures at number 1-10 then speak about how the air travels in the body. sinuses trachea bronchus pharynx nasal passages diaphragm lung external nares larynx epiglottis 100 http://www.highlands.edu/academics/divisions/scipe/biology/faculty/hargett/b2122/2122rev3/rspdia.htm 4.2 MUSCLES OF RESPIRATION, PHYSIOLOGY OF THE RESPIRATORY SYSTEM READING 4.2.1 Respiration (R) Read the text and answer the questions below. 1) 2) 3) 4) 5) 6) 7) 8) 9) 10) Define the diaphragm in simple terms. What are the sections of the intercostal muscles? How do the sections of the intercostal muscles work? Define pulmonary ventilation in simple terms. What is used to achieve pulmonary ventilation? What is gas exchange facilitated by? What happens during inspiration? Is expiration an active or passive process? Why? What is external respiration in simple terms? What is internal respiration in simple terms? 101 Surrounding the lungs are sets of muscles that are able to cause air to be inhaled or exhaled from the lungs. The principal muscle of respiration in the human body is the diaphragm, a thin sheet of skeletal muscle that forms the floor of the thorax. Between the ribs are many small intercostal muscles that assist the diaphragm with expanding and compressing the lungs. These muscles are divided into 2 groups: the internal intercostal muscles and the external intercostal muscles. The internal intercostal muscles are the deeper set of muscles and depress the ribs to compress the thoracic cavity and force air to be exhaled from the lungs. The external intercostals are found superficial to the internal intercostals and function to elevate the ribs, expanding the volume of the thoracic cavity and causing air to be inhaled into the lungs. http://paramedicine101.com/2010/10/17/respiratory-system/ Pulmonary Ventilation Pulmonary ventilation or breathing is the process by which gases are exchanged between the atmosphere and lung alveoli. The exchange of gases is facilitated by changes in pressure between the atmosphere and the lung alveoli. The respiratory system uses both a negative pressure system and the contraction of muscles to achieve pulmonary ventilation. The volume of the lungs is increased during inspiration. During inspiration; The diaphragm contracts and flattens which increases the vertical dimension of the thoracic cavity. The chest wall lifts up and out increasing the horizontal dimension of the thoracic cavity. In turn the pleural cavity increases causing a drop in intrapleural pressure. Therefore the parietal pleura are pulled outwards by the expanding thoracic cavity. The parietal pleura also pull the visceral pleura and the lungs out with them. 102 Expiration Expiration or breathing out also occurs due to changing pressure gradients. For expiration to occur the opposite conditions to inspiration must occur, i.e. the pressure in the lungs must be greater than the atmospheric pressure. Expiration, unlike inspiration, is a passive process, i.e. no muscle contractions are involved. Expiration therefore occurs due to the elastic recoil of the chest wall and lungs, both of which spring back to their original shape after being stretched. http://everything2.com/title/Pulmonary+ventilation http://g09respirationr3a.wikispaces.com/(4)%09+Breathing+%26+gas+exchange External Respiration External respiration is the exchange of gases between the air filling the alveoli and the blood in the capillaries surrounding the walls of the alveoli. The net result of external respiration is the movement of oxygen from the air into the blood and the movement of carbon dioxide from the blood into the air. The oxygen can then be transported to the body’s tissues while carbon dioxide is released into the atmosphere during exhalation. Internal Respiration Internal respiration is the exchange of gases between the blood in capillaries and the tissues of the body. The net result of internal respiration is the diffusion of oxygen into the tissues and the diffusion of carbon dioxide into the blood. http://everything2.com/title/Pulmonary+ventilation 103 SPEAKING 4.2.2 Health effects of smoking (S) 1. What is the connection between the pictures? Work in pairs. You should talk about your ideas. You can develop a talk by commenting the pictures or raising problems related to them. http://www.livescience.com/26063-smokers-quit-new-years-resolution.html http://en.wikipedia.org/wiki/Tobacco_smoking http://diseasespictures.com/lung-cancer/ http://dailymuslims.com/wp-content/uploads/2013/07/smoking-danger.jpg http://www.sharp-smoker.com/e-cigarette-dangers-s/128.htm 2. With a partner answer the following questions. What kind of addictions do you know? Why do people smoke? Give reasons. What diseases can be related to the harmful effects of smoking? What should be done to reduce smoking among young people? What is an E-cigarette? What do you think about it? Do you think that ’no-smoking days’ and anti-smoking campaigns are effective? Justify your opinion. What would you do to prevent your children from smoking? What tips would you give to smokers to help them quit smoking? What is nicotine replacement therapy? 104 WRITING 4.2.3 Decreasing smoking rates (W) Read and discuss the following text in groups of 3, then make and write suggestions on how to decrease smoking rates. Each group will then write 2 of their suggestions on the board when ready. Tobacco is the single largest avoidable health risk in the EU, accounting for nearly 700 000 premature deaths each year. Around 50% of smokers die prematurely (on average 14 years earlier). In addition, smokers have more life years in poor health. Many cancers, cardiovascular and respiratory diseases are linked to tobacco use, which causes more problems than alcohol, drugs, high blood pressure, excess weight or high cholesterol. Despite considerable progress, the number of smokers in the EU is still high – 28% of the population and even 29% of young Europeans aged 15-24. Because tobacco is so addictive and 94% of smokers start smoking before they turn 25, policy should focus on preventing young people from starting smoking. http:/ec.europa.eu/health/tobacco/introduction/index_en.htm SPEAKING 4.2.4 Types of cough (S) Read the text about cough then with a partner discuss what the common causes for acute, subacute and chronic coughs are? Write your ideas into the table. A cough is a natural reflex that protects your lungs. Coughing helps clear your airways of lung irritants, such as smoke and mucus. This helps prevent infections. A cough can also be a symptom of a medical problem. A cough can be acute, subacute, or chronic, depending on how long it lasts. An acute cough lasts less than 3 weeks. A subacute cough lasts 3 to 8 weeks. A chronic cough lasts more than 8 weeks. Types of caugh acute Conditions subacute chronic http://www.nhlbi.nih.gov/health/health-topics/topics/cough/ 105 4.3 DISEASES OF THE RESPIRATORY SYSTEM READING 4.3.1 Lung cancer (R) 1. Read the text and fill in the table with the most important information about lung cancer. Lung cancer is surely deadliest of all other types of cancer and each year thousands of people die of lung cancer. Very often it develops on adults who are above 50 years. Lung cancer has every possibility to spread to brain, adrenal glands and liver causing death. The types of lung cancer are small celled lung cancer and non-small cell lung cancer. Non small type of cancer develops in almost 85% of lung cancer people. Metastatic lung cancer is the one which starts in any part of the body and subsequently spreads to lungs. The main cause of lung cancer is smoking. Smoking tobacco in any form can cause lung cancer. But there are thousands of people with lung cancer who have not even smoked once in life. Working in asbestos prone environment and exposure to strong chemicals like beryllium, gasoline, nickel chromates and chloro-methyl ether certainly will increase the risk of lung cancer. People who have COPD (Chronic Obstructive Pulmonary Disease) have increased chance of getting lung cancer. People who are subjected to a high level of air pollution, who drink water that has high arsenic content are at risk of developing lung cancer. Lung cancer will not produce symptoms initially. Some people may get chest pain, persistent cough, and blood with cough. Loss of appetite, loss of weight, wheezing and breathing problems are common later. During advanced stages there may be joint pains, facial paralysis, eyelid drooping, bone pains, should and nail problems. Since these signs are also indicative of other small diseases, you need to consult your doctor for preventing the risk. Doctors will ask you to take X-ray and CT scan or bronchoscopy for checking the lung cancer. Treatment is available in several forms like surgery, radiotherapy, chemotherapy, photo dynamic therapy and radiofrequency ablation. Surgery involves removal of cancer causing tumor from the lungs. Depending on the size of tumor and its position, surgeons will open the chest wall and will remove the cancer portion of the lobe and also the lymph nodes in the lungs. Radiation therapy is best suited for both types of lung cancer, which uses high power radiation for killing cancerous cells inside. Radiation therapy is combined with surgery or chemotherapy for getting the best results. In chemotherapy drugs are given for stopping the growth of cancerous cells inside. http://diseasespictures.com/lung-cancer/ http://kisbyto.blogspot.hu/2012/11/lung-cancer-awareness-month.html 106 Risk group Types of lung cancer Causes of lung cancer Symptoms Diagnosis Treatment 2. With the help of your notes above talk about lung cancer. VOCABULARY 4.3.2 COPD (V) Match the words (1-6) with the definitions (a-f). 1) 2) 3) 4) 5) 6) springy __________ inflate __________ deflate__________ ephysema __________ chronic bronchitis __________ ebolectomy__________ a) in this disorder any irritant reaching the bronchi and bronchioles will stimulate an increased secretion of mucus, the air passages become clogged with mucus, and this leads to a persistent cough b) in this disorder the delicate walls of the alveoli break down, reducing the gas-exchange area of the lungs c) emergency surgical removal of emboli which are blocking blood circulation d) to become filled with gas or air e) returning quickly to the original shape after being pushed, pulled, stretched f) to become smaller because of air or gas coming out http://en.wikipedia.org/wiki/Embolectomy 107 LISTENING 4.3.3 Chronic Obstructive Pulmonary Disease causes (L) Watch the video and answer the questions. Source: https://www.youtube.com/watch?v=2nBPqSiLg5E 1. What is COPD? 2. What are your airways and alveoli normally like? 3. What do the air sacs do when you inhale and exhale? 4. What is the leading cause of COPD? 5. What are the other causes of COPD? 6. What are the 2 main conditions of COPD? 7. What are the symptoms of emphysema? 8. What are the symptoms of chronic bronchitis? 9. Is damage done to the lung by COPD reversible? 10. What is the treatment for COPD? http://www.tabletsmanual.com/wiki/read/pulmonary_emphysema_and_bronchitis 108 READING 4.3.4 COPD Quiz (R) Test your knowledge about COPD. Circle the correct letters. Question 1. COPD is a lung disease that: A. usually starts during childhood and develops quickly B. makes it hard to breathe and gets worse over time C. is passed from person to person Question 2. In the United States, the term "COPD" describes two main conditions in the lungs: A. emphysema and pulmonary hypertension B. cystic fibrosis and chronic bronchitis C. emphysema and chronic bronchitis Question 3. The most common lung irritant that causes COPD is: A. allergens B. cigarette smoke C. air pollution Question 4. Common signs and symptoms of COPD include: A. fever B. an ongoing cough, or a cough that produces large amounts of mucus, and shortness of breath C. a racing heartbeat Question 5. If you have COPD, which steps can you take to prevent complications and slow the progress of the disease? A. quit smoking and avoid secondhand smoke B. avoid other lung irritants, such as air pollution, chemical fumes, and dust C. follow your treatment plan for COPD exactly as your doctor prescribes D. all of the above http://www.nhlbi.nih.gov/health/health-topics/quizzes/copd-quiz.html 109 SPEAKING 4.3.5 Doctor- Patient conversation (S) With a partner, act out the roles below. Student A: You are a doctor. Student B has been diagnosed with COPD. You have to explain: the condition the severity of the disease (Student B has been a chain smoker for 5 years) treatment options tips to help him/her give up smoking (nicotine replacement therapy etc.) Student B: You are a patient. You are at your doctor’s office. You want to know the diagnosis for your constant cough, wheezing and chest tightness. You ask about: the condition the severity of the disease if the disease can be healed advice on how to give up smoking 4.4 OTHER LUNG CONDITIONS AND ASTHMA READING 4.4.1 Other lung conditions (R) Read the description of the following lung conditions and match them with their names. asthma pulmonary embolism tuberculosis bronchiectasis pneumonia 110 1.____________________ It is an infection in one or both of the lungs. Many germs—such as bacteria, viruses, and fungi—can cause it. The infection inflames your lungs' air sacs. The air sacs may fill up with fluid or pus, causing symptoms such as a cough with phlegm, fever, chills, and trouble breathing. http://www.nhlbi.nih.gov/health/health-topics/topics/pnu/ 2.____________________ is a sudden blockage in a lung artery. The blockage usually is caused by a blood clot that travels to the lung from a vein in the leg. A clot that forms in one part of the body and travels in the bloodstream to another part of the body is called an embolus. http://www.nhlbi.nih.gov/health/health-topics/topics/pe/ http://healthcare.utah.edu/healthlibrary/related/doc.php?type=85&id=P01308 3. ____________________ chronic (long-term) lung disease that inflames and narrows the airways. It causes recurring periods of wheezing (a whistling sound when you breathe), chest tightness, shortness of breath, and coughing. The coughing often occurs at night or early in the morning http://www.nhlbi.nih.gov/health/health-topics/topics/asthma/ 111 4. ____________________ is a bacterial infection that can spread through the lymph nodes and bloodstream to any organ in your body. It is most often found in the lungs. The bacteria causing the disease can live in an inactive form in the body. But if the immune system weakens, these bacteria can become active. In their active state, they cause death of tissue in the organs they infect. Common symptoms include: a cough with thick, cloudy, and sometimes bloody mucus from the lungs for more than 2 weeks, fever, chills, and night sweats. http://www.webmd.com/lung/tc/tuberculosis-tb-symptoms 5.____________________ This is a condition in which damage to the airways causes them to widen and become flabby and scarred. This prevents the airways from properly moving mucous out of your lungs. An infection or other condition that injures the walls of the airways usually causes this disease . http://www.nhlbi.nih.gov/health/health-topics/topics/cough/causes.html Asthma http://www.nlm.nih.gov/medlineplus/magazine/issues/fall11/articles/fall11pg4.html 112 LISTENING 4.4.2 Asthma (L) 1. Listen to the recording about asthma. Number the prompts in the order you hear them in the text. Source: https://www.youtube.com/watch?v=7EDo9pUYvPE _______ severity of symptoms _______ asthmatic triggers _______ the part of the body asthma affects _______ what asthma causes _______ onset of asthma _______ what happens during breathing 2. Listen again and complete the sentences with the missing information. a) Asthma is a 1._________________________, long-term condition that can be managed but 2. _________________________ b) It causes 3. _________________________ resulting in wheezing and difficulty breathing. c) In asthma the airways are 4. _________________________ and easily irritated by certain triggers called asthmatic triggers. d) Most people with asthma are described 5. _________________________ meaning they have an allergic-type reaction to external triggers. e) External triggers are 6. _________________________, pollen, cigarette smoke, animal fur and chest infections. f) For some people the onset of asthma is 7. _________________________ and may be caused by anxiety, stress or even laughter. g) An asthmatic trigger causes the airway walls to swell and the muscles around the airways to 8. _________________________. h) The airways narrow and breathing through them produces a whistling sound called 9. _________________________. i) Symptoms of asthma can be 10. _________________________ or life threatening, where hospital treatment is needed. 113 SPEAKING 4.4.3 Doctor-Patient conversation (S) With a partner, act out the roles below. Student A: You are a family doctor. Your patient seems to have asthma. You ask him/her about: family history of asthma when and how often the symptoms occur what factors seem to trigger the symptoms recommend some tests which are needed to make a diagnosis (x-ray, ECG, allergy test, spirometry* Student B: You turn to your family doctor with asthma symptoms. You are especially worried as your mother has asthma, too. Talk about: your complaints (wheezing, caugh, difficulty breathing, 4 times a week, after doing physical exercise or when you are stressed) treatments to diagnose your problem *spirometry: Spirometry measures how much air you breathe in and out and how fast you blow it out. This is measured two ways: peak expiratory flow rate (PEFR) and forced expiratory volume in 1 second (FEV 1). PEFR is the fastest rate at which you can blow air out of your lungs. FEV1 refers to the amount of air you can blow out in 1 second. During the test, a technician will ask you to take a deep breath in. Then, you'll blow as hard as you can into a tube connected to a small machine. The machine is called a spirometer. http://www.nhlbi.nih.gov/health/health-topics/topics/lft/types.html 114 4.5 VOCABULARY ablation air passages alveolar alveolus/alveoli benign bronchial bronchiole bronchitis bronchus/bronchi cartilage cilium/cilia cricoic cartilage diaphragm elastin emphysema epiglottis epithelium esophagus flabby frontal sinus glottis hyaline hyoid bone intercostal muscles larynx malignant metastatic mucous membrane nares nostril pharynx pleura pus ribcage scarred sinus sphenoid sphenoid sinus squamous sternum superior concha tertiary eltávolítás légutak léghólyagocskákra vonatkozó léghólyagocska jóindulatú hörgőbronchiolus, apró hörgő hörghurut hörgő porc csilló gyűrűporc rekeszizom elasztin tüdőtágulás gégefedő hám nyelőcső ernyedt homloküreg hangrés hialin nyelvcsont bordaközti izmok gége rosszindulatú áttétes nyálkahártya orrlyuk orrlyuk, orrcimpa garat mellhártya genny bordakosár forradásos, sebhelyes melléküreg ékcsont sinus sphenoidalis pikkelyes szegycsont felső orrkagyló harmadlagos, tercier 115 thorax thyroid cartilage trachea tuberculosis turbinates mellkas pajzsporc légcső gümőkór orrkagylók 116 UNIT 5. THE IMMUNE SYSTEM Aims of the Unit In this unit you will learn about: the immune system, autoimmune diseases, organ transplantation, celiac disease and AIDS. 117 5.1 OVERVIEW OF THE IMMUNE SYSTEM VOCABULARY DEVELOPMENT 5.1.1 Brainstorming – Immune System (V) In pairs, collect ideas to the topic ’Immune System’. IMMUNE SYSTEM VOCABULARY DEVELOPMENT 5.1.2 Basic terms (V) Match the words (1-10) with the definitions (a-j) 1 2 1) 2) 3) 4) 5) 6) 7) 8) 9) 10) 11) 12) 3 4 5 6 7 8 9 10 11 immune response natural killer cell (NK cell) stem cells immunocompromised extracellular fluid lymphocytes B cell thymus T cell immunological memory immune tolerance autoimmune disease a) A state in which a person's immune system is weakened or absent. b) A small white blood cell (leukocyte) that plays a large role in defending the body against disease. They are responsible for immune responses. 118 c) A type of white blood cell and, specifically, a type of lymphocyte. These cells make antibodies that attack bacteria and toxins. d) A type of white blood cell that attacks body cells themselves. e) Any reaction by the immune system f) A cell that can react against and destroy another cell without prior sensitization to it, it is part of our first line of defense against cancer cells and virus-infected cells. g) They are primitive cells that have the potential to differentiate, or develop into, a variety of specific cell types. h) The capacity of the body's immune system to remember an encounter with an antigen due to the activation of B cells or T cells having specificity for the antigen and to react more swiftly to the antigen by means of these activated cells in a later encounter. i) An organ that is located in the upper chest behind the breastbone and in front of the lower neck in which the immune cells called T lymphocytes mature and multiply in early life. j) Body fluid that is not contained in cells. It is found in blood, in lymph, in body cavities lined with serous membrane, in the cavities and channels of the brain and spinal cord, and in muscular and other body tissues. k) An illness that occurs when the body tissues are attacked by its own immune system. Some examples include systemic lupus erythematosus, Sjogren syndrome, Hashimoto thyroiditis, rheumatoid arthritis, juvenile (type 1) diabetes etc. l) A state of unresponsiveness to a specific antigen or group of antigens to which a person is normally responsive. It is achieved under conditions that suppress the immune reaction. The T cell "tolerates" the antigen. http://www.medicinenet.com/stem_cells/article.htm#what_are_stem_cells http://search.medicinenet.com http://www.britannica.com READING 5.1.3 Function and location of the Immune System (R) Read and complete the text with the missing words from the box. pervasive lymphocytes immune response innate immune cells release microbes stems cells infection immunocompromised autoimmune disease lymph precursors The immune system is a network of cells, tissues, and organs that work together to protect the body from 1. ____________________. The human body provides an ideal environment for many 2. ____________________, such as viruses, bacteria, fungi, and parasites, and the immune system prevents and limits their entry and growth to maintain optimal health. The overall function of the immune system is to prevent or limit infection. An example of this principle is found in 3. ____________________ people, including those with genetic immune disorders, immune-debilitating infections like HIV, and even pregnant women, who are susceptible to a range of microbes that typically do not cause infection in healthy individuals. 119 The immune system can distinguish between normal, healthy cells and unhealthy cells by recognizing a variety of "danger" cues called danger-associated molecular patterns (DAMPs). Cells may be unhealthy because of infection or because of cellular damage caused by non-infectious agents like sunburn or cancer. Infectious microbes such as viruses and bacteria 4. ____________________ another set of signals recognized by the immune system called pathogen-associated molecular patterns (PAMPs). When the immune system first recognizes these signals, it responds to address the problem. If an 5. ____________________ cannot be activated when there is sufficient need, problems arise, like infection. On the other hand, when an immune response is activated without a real threat or is not turned off once the danger passes, different problems arise, such as allergic reactions and 6. ____________________. The immune system is complex and 7. ____________________. There are numerous cell types that either circulate throughout the body or reside in a particular tissue. Each cell type plays a unique role, with different ways of recognizing problems, communicating with other cells, and performing their functions. All immune cells come from 8. ____________________in the bone marrow and develop into mature cells through a series of changes that can occur in different parts of the body. Skin: The skin is usually the first line of defense against microbes. Skin cells produce and secrete important antimicrobial proteins, and immune cells can be found in specific layers of skin. Bone marrow: The bone marrow contains 9. ____________________ that can develop into a variety of cell types. The common myeloid progenitor stem cell in the bone marrow is the precursor to 10. ____________________ —neutrophils, eosinophils, basophils, mast cells, monocytes, dendritic cells, and macrophages—that are important first-line responders to infection. The common lymphoid progenitor stem cell leads to adaptive immune cells—B cells and T cells—that are responsible for mounting responses to specific microbes based on previous encounters (immunological memory). Natural killer (NK) cells also are derived from the common lymphoid progenitor and share features of both innate and adaptive immune cells, as they provide immediate defenses like innate cells but also may be retained as memory cells like adaptive cells. B, T, and NK cells also are called 11. ____________________. Bloodstream: Immune cells constantly circulate throughout the bloodstream, patrolling for problems. When blood tests are used to monitor white blood cells, another term for immune cells, a snapshot of the immune system is taken. If a cell type is either scarce or overabundant in the bloodstream, this may reflect a problem. Thymus: T cells mature in the thymus. Lymphatic system: The lymphatic system is a network of vessels and tissues composed of 12. ____________________, an extracellular fluid, and lymphoid organs, such as lymph nodes. The lymphatic system is a conduit for travel and communication between tissues and the bloodstream. Immune cells are carried through the lymphatic system and converge in lymph nodes, which are found throughout the body. Lymph nodes are a communication hub where immune cells sample information brought in from the body. Spleen: It is important for processing information from the bloodstream. Immune cells are enriched in specific areas of the spleen, and upon recognizing blood-borne pathogens, they will activate and respond accordingly. Mucosal tissue: Mucosal surfaces are prime entry points for pathogens, and specialized immune hubs are strategically located in mucosal tissues like the respiratory tract and gut. http://www.niaid.nih.gov/topics/immuneSystem/Pages/overview.aspx 120 http://jo-dieta-sikeres-fogyas.hupont.hu/8/immunrendszer LISTENING 5.1.4 Immune Response to Bacteria (L) Listen to the recording and decide if the following statements are true (T) or false (F). Source: http://www.youtube.com/watch?v=skPtWocTKdU 1) 2) 3) 4) 5) 6) 7) 8) Tiny cuts on the skin can start an infection. _____ Inflammation at the wound site releases chemical signals. _____ Inflammation is a type of defense. _____ One layer below the damaged skin we can find neutrophils, which are a type of red blood cells. _____ Neutrophils circulate in the blood stream looking for signals of infection and kill harmful bacteria. _____ Outside the phagosome, the isolated bacteria are surrounded by swirling granules which release killing elements into the phagosome. _____ Protein complexes generate clouds of deadly agents to help kill the bacteria, while other granules continue to fuse with the phagosome, releasing many other different agents that also contribute to killing the bacteria. _____ Within some minutes, the immediate threat to the body has been eliminated. _____ 121 SPEAKING 5.1.5 Immune System Boosters and Busters (S) In pairs, discuss the following questions. 1. What kind of good habits can help keep your immune system healthy? 2. What are immune-boosting foods? Can you name them? Can you list some more? 1. _________________________ 2. _________________________ 3. _________________________ 4. _________________________ 5. _________________________ 6. _________________________ http://www.webmd.com/cold-and-flu/10-immune-system-busters-boosters 3. Why does our immune system get weak? 4. What nutrients boost the immune system? 5. What nutrients make harm to the immune system? 122 5.2 AUTOIMMUNE DISEASES READING 5.2.1 Getting to know about autoimmune diseases (R) 1. How much do you know about autoimmune diseases? Can you name the conditions in the pictures? http://www.bing.com/images/search?q=psoriasis&FORM=HDRSC2#view=detail&id=D5D6CBE6B85FB900930AB6FFFBC4BE79D5954AF7&selectedIndex=8 http://healthtohappinies.blogspot.hu/2012/02/identify-disease-diabetes-mellitus-dm.html http://www.bing.com/images/search?q=First+Symptoms+Lupus&Form=IQFRDR#view=detail&id=592A25FA45B8DF714218296CBC4F67454867FA4A&selectedI ndex=0 http://www.bing.com/images/search?q=Graves%27+Disease+Eye+Symptoms&Form=IQFRDR#view=detail&id=C895FCD242198623996DF1E1E1269CC2B483E9 91&selectedIndex=12 2. Can you name some more autoimmune diseases? 3. Test your knowledge about autoimmune diseases. Do the quiz below. 1. Which of these is an autoimmune disease? A. Type 1 diabetes B. Rheumatoid arthritis C. Psoriasis D. AIDS E. A, B, and C 123 2. If a person has an autoimmune disease, what happens with the immune system? A. The person's immune cells die B. Antibodies from the person's immune system mistakenly attack tissues in the body C. The person's immune system produces too many immune cells D. None of the above 3. Autoimmune diseases strike which group more often? A. Children younger than 12 B. Men older than 40 C. Women of childbearing age D. Women older than 50 4. What tissues, organs, or body systems can be affected by autoimmune diseases? A. Skin B. Joints C. Thyroid D. All of the above 5. Lupus is more common among women in which ethnic group? A. Caucasians B. African-Americans C. Hispanics D. B and C 6. How does a person develop an autoimmune disease? A. It may be triggered by a virus, such as mumps B. It may be a complication of an existing infection, such as strep throat C. It may be caused by exposure to an environmental agent D. Most do not have an obvious cause E. All of the above 7. Why are some autoimmune diseases difficult to diagnose? A. Symptoms may be vague B. No specific lab tests exist to confirm a diagnosis C. Symptoms may come and go, making it hard to pinpoint the problem D. All of the above 8. Which of these autoimmune diseases can be cured? A. Lupus B. Multiple sclerosis C. Scleroderma D. None of the above http://www.urmc.rochester.edu/encyclopedia/document.aspx?ContentTypeID=40&ContentID=AutoimmuneDiseaseChrQui z 124 http://maciociaonline.blogspot.hu/2013/01/the-treatment-of-autoimmune-diseases.html LISTENING 5.2.2 Multiple sclerosis (L) 1. Read the text about multiple sclerosis and try to complete it with the missing words. Then listen to the recording and check your answers. Source: https://www.youtube.com/watch?v=qgySDmRRzxY Multiple sclerosis, MS is a disease that affects the central nervous system, the CNS, which consists of the 1. _______________ , spinal cord, optic nerves. Everything we do, whether taking a step, solving a problem or simply breathing relies on the proper functioning of the CNS. To understand how MS may impact the CNS, we must explore the disease at the 2. _______________ level. In the brain millions of nerve cells called 3. _______________ continually send and receive signals. Each signal is a minute but necessary part of intricate CNS orchestrations that culminate in the actions, sensations, thoughts and 4. _______________ that comprise the human experience. Normally, the path over which a nerve signal travels is protected by a type of insulation called the myelin sheath. This insulation is essential for nerve signals to reach their 5. _______________ . In MS the myelin sheath is eroded and the underlying wirelike nerve fiber is also damaged. This leads to a breakdown in the ability of the nerve cells to 6. _______________ signals. It is believed that the loss of the myelin is the result of mistaken 7. _______________ by immune cells. Immune cells protect the body against foreign substances such as bacteria and 8. _______________, but in MS something goes awry. Immune cells infiltrate the brain and spinal cord, seek out the myelin and attack as ongoing 125 inflammation and tissue 9. _______________ occurs. Nerve signals are disrupted, this causes unpredictable symptoms that range from numbness to blindness and paralysis. These losses may be temporary or 10. _______________ . 2. What is MS due to? Explain it in your own words. 3. Read the text below about types and diagnosis of MS then sum it up in your own words. Types of Multiple Sclerosis Multiple sclerosis may appear in several forms. The types of MS include: Relapsing-remitting: This form of multiple sclerosis comes and goes over time. Symptoms can be severe for a time but then disappear. About 85 percent of multiple sclerosis patients develop onset of the disease in this manner (Murray, T., et al., 2013). Secondary-progressive: After the initial attack, the disease may begin to progress in a more deliberate way. In this type of MS, symptoms do not subside. Before new therapies were created, about 50 percent of people with multiple sclerosis entered a progressive stage. However, the effectiveness of the new therapies has not been fully evaluated (Murray T., et al, 2013). Primary-progressive: People who develop this form of the disease generally do so later in life. They decline slowly, without many ups and downs. Progressive relapsing: In this form of multiple sclerosis, symptoms initially progress slowly but eventually worsen over time. How Is Multiple Sclerosis Diagnosed? There is no definitive diagnosis for multiple sclerosis. Doctors determine whether you have it by ruling out other illnesses. They do this by evaluating your symptoms, performing a clinical exam, and ordering tests. Tests that may point to a possible multiple sclerosis diagnosis include: Magnetic resonance imaging (MRI): MRIs allow doctors to identify lesions in your brain or spinal cord, which could indicate myelin loss. Spinal tap: The fluid in your spine can offer clues about whether your body is experiencing an immune response. Spinal fluid abnormalities are often present in a diagnosis of the disease. Evoked potential test: This test uses visual cues or electrical impulses to determine how efficiently your brain responds to stimuli. Blood tests: Blood tests may rule out other disorders. http://www.healthline.com/health/multiple-sclerosis 126 http://www.medimiss.net/2013/12/common-symptoms-of-multiple-sclerosis.html http://www.jennifersweeney.ca/2013/09/14/my-first-clear-sign-of-multiple-sclerosis/ 127 4. Listen to the recording about ’How to manage symptoms of relapsing-remitting MS’ and fill in the table with the information from the audio. Source: http://www.youtube.com/watch?v=sOKKT--eC4c Symptoms The most common form of MS/severity of symptoms Areas of life MS may affect Treatment Activities to help ease MS Most important things to do 5. With the help of your notes speak about ’How to manage relapsing-remitting MS’. SPEAKING 5.2.3 Living with MS (S) In pairs, discuss the following questions. How can people feel diagnosed with MS? What can their reactions be? How can their parents, partners, children react to the diagnosis? Is there a right/wrong time or way to tell the diagnosis to parents, partners and children? What kind of questions would you expect as a doctor from your patient after being diagnosed with MS? 128 LISTENING 5.2.4 Coping with MS diagnosis (L) 1. Watch the video about ’Coping with a diagnosis of MS’. What do the people in this video talk about? Source: https://www.youtube.com/watch?v=_cyjphUUNVE#t=210 2. Watch the video again and answer the questions below! How did the people in the video react to the diagnosis? Give examples. How did their family members, friends react? What kind of changes did they have to do in their lives? 3. Was there anything in the video that surprised you? If yes, what? 129 WRITING 5.2.5 Giving advice (W) You have just read Lucy’s letter on Patient.co.uk discussion forum. She finds it very difficult to tell her parents that she has MS. Reply to her in 170-180 words. Mention the reasons why she should tell her parents that she has MS the possible reactions that her parents might have the changes she will have to make over time in her life and the role of the family in that some good advice on how to relate to her condition Ok, this is what I'm most concerned about for a different reason to what you may all be thinking!! I've had severe arthritis in my knees and spine for the last 32yrs, since I was a child - it absolutely disables and floors me, completely!! Turns out, that this could actually have been MS all along....now along the way I've had a few problems with my health and whenever I've actually tried to say anything to my parents - They've always been sicker than me, in more pain than me, on more pills than me....it has got to the point where I haven't even told them about all of my tests over the last 3 years; the biopsies due to bleeding and pain 'downstairs', the XRays, the ECG's, the many different Specialists appointments....and lastly, the more scary....the Brain Scan!! Very Scary!! I have my Husband with me at every appointment, which is all I need.....but I'm working myself up about telling my Parents!! My whole life I've been talked over by her & ignored and it has left me not wanting to tell them anything really! I've been left with no choice because I know that she is talking about me behind my back to the family - that I don't do anything to help them etc., but I'm in such a state every time I've helped them - even the 3hr round trip to see them makes me so ill......what do you all suggest....I've already got it into my head to tell them not to interrupt me while I tell them something......it's driving me insane! Lucy 523 http://www.patient.co.uk/forums/discuss/how-did-you-all-tell-your-parents-that-you-had-ms-145026 130 SPEAKING 5.2.6 Talking about MS (S) With the help of the prompts, talk about Multiple Sclerosis. part of the body it affects damage done to the nerves types of MS common symptoms diagnosis treatment recommended activities for MS patients to ease the symptoms 5.3. ORGAN TRANSPLANTATION VOCABULARY DEVELOPMENT 5.3.1 Background Vocabulary (V) Match the words (1-9) with the definitions (a-h). 1 1) 2) 3) 4) 5) 6) 7) 8) 9) 2 3 4 5 6 7 8 9 transplantation donor recipient graft/transplant implantation HLA (human leukocyte antigen) antigen „match” rejection donation a. The insertion of an organ or tissue in a new site in the body. b. They are proteins that are located on the surface of the white blood cells and other tissues in the body, determining graft/host tissue compatibility (by identification of ’self’ or ’non self’ tissue moieties) and allowing tissue typing. 131 c. When two people share the same Human Leukocyte Antigens, that is, their tissues are immunologically compatible with each other. d. To transfer tissue or an organ from one body or body part to another. e. One who receives a blood transfusion, or a tissue or organ graft. f. Any tissue or organ for implantation or transplantation. i. An individual from whom blood, tissue, or an organ is taken for transfusion, implantation, or transplantation. g. The act of giving. h. The immune reaction of a recipient to a graft after transplantation. http://medical-dictionary.thefreedictionary.com SPEAKING 5.3.2 Organ Transplantation - Frequently Asked Questions (S) In pairs, discuss the following questions. What organs can be donated for transplantation? Is there a need for organ and tissue donors? Who can become a donor? What is living donation and what organs can be donated while one is alive? Is there an age limit for donating organs? Will the identity of the recipients be revealed to the donor family? What is meant by brain death? What do you personally think about donating organs? Would you become a donor? READING 5.3.3 The Immune System and Organ Transplant (R) Read the text about ‘Organ Transplant’ and answer the questions below. Some people may have diseases that lead to organ failure, or they may have suffered an injury that would require an organ transplant. Major organs that may be transplanted include: Heart Lungs Kidneys Pancreas 132 Liver Intestines While many organ transplants are successful, there is still a chance that the recipient's immune system will reject the transplanted organ. Before a patient can have an organ transplant, they will take a blood test that will allow doctors to perform tissue typing. This lets doctors check the compatibility between donor and recipient tissues by comparing HLA markers. Because everyone’s HLA markers are different, with the exception of identical twins, matches must be as close as possible. Without a close match, the organ will be rejected, and T cells will begin their attack. There are three types of organ rejection: Hyperacute rejection — Rare, but can occur within minutes of a transplant. Acute rejection — Can occur a few weeks after a transplant, but the greatest risk is within the first six months after the transplant. Chronic rejection — Can occur months after a transplant. The cause is unknown, but it may be linked to non-adherence to antirejection medications. Regardless of how well-matched a donor and recipient are, the recipient’s body will still try to reject the new organ since it is made completely of foreign cells. Fortunately, there are ways for patients and doctors to work together to prevent rejection or infection. While treatments and health care will vary depending on the organ transplanted and the patient, most recovery programs will involve similar care. To prevent rejection, immunosuppressant drugs will be given to decrease the body’s normal immune response. These drugs will need to be taken for the rest of the patient’s life. Since these drugs reduce the immune system’s ability to fight other types of infections, a combination of antiviral, antifungal, and antibiotic medications may also be prescribed. Medications may have a number of side effects, such as headache, nausea, and weight gain. They may also cause problems such as high blood pressure or high cholesterol. There is also an increased risk of cancer as a result of suppressing the immune system. However, the risk of cancer may vary depending on different factors such as which medications are chosen, age, or whether there is a family history of cancer. Some women worry about becoming pregnant after an organ transplant. While there are risks involved, particularly during the first year after surgery when the risk of rejection is highest, many women have successfully had children after their transplant. Those who plan to receive organ transplants are required to stop smoking or using other drugs and alcohol in order to stay on the waiting list for an organ transplant. After surgery, some may find it hard to avoid old habits. http://www.med.nyu.edu/content?ChunkIID=524642 1) In what cases may an organ transplant be necessary? 2) What do doctors do before a patient can get an organ transplant? 3) Whose HLA markers are the same? 4) What kind of organ rejections are there? 5) What is expected after an organ transplant? 6) How is rejection pervented? 7) What are the dangers of immunosuppresant drugs? 8) What additional health concerns can occur after an organ transplant? 133 5.4 FOOD ALLERGY VOCABULARY DEVELOPMENT 5.4.1 Major allergenic foods (V) A group of the eight major allergenic foods is often referred to as the Big-8. What does it comprise? Look at the pictures. Can you name them? 1. _________________ 2. _________________ 3. _________________ 4. _________________ 5. _________________ 6. _________________ 134 7. _________________ 8. _________________ http://farrp.unl.edu/informallbig8 LISTENING 5.4.2 Understanding food allergy (L) 1. Decide if the following statements are true (T) or false (F). 1) Food allergies are not real. _______ 2) Food allergies are not life threatening. _______ 3) Food additives and artificial flavors cause the majority of food allergic reactions. _______ 4) Each allergic reaction to food becomes increasingly worse. _______ http://farrp.unl.edu/resources/gi-fas/food-allergy-myths 2. Listen to the following recording about ’food allergy’ and answer the questions below. Source: http://www.youtube.com/watch?v=AKVjKC3u9hk 135 1) What kind of antibody does the immune system make if you have food allergy? 2) What kind of cells are mast cells or basophils? 3) What happens when a food allergen attaches to the IgE antibody? 4) When does an allergic reaction occur? 5) What is the most severe kind of allergic reaction is called? 6) Who are more susceptible to severe reactions? 7) What is an anaphylactic episode is treated with? 8) What kind of medical device is prescribed to people diagnosed with food allergy? 9) What is the best way to manage allergic reactions? 10) What should a patient do who is accidentally exposed to a food allergen? READING 5.4.3. Food Allergy – Everything you need to know (R) Read the text about ’Food Allergy’ and fill in the table below then talk about food allergy with the help of your notes. The job of the body’s immune system is to identify and destroy germs (such as bacteria or viruses) that make you sick. A food allergy results when the immune system mistakenly targets a harmless food protein – an allergen – as a threat and attacks it. Unlike other types of food disorders, such as intolerances, food allergies are “IgE mediated.” This means that your immune system produces abnormally large amounts of an antibody called immunoglobulin E — IgE for short. IgE antibodies fight the “enemy” food allergens by releasing histamine and other chemicals, which trigger the symptoms of an allergic reaction. An allergic reaction to food can affect the skin, the gastrointestinal tract, the respiratory tract, and, in the most serious cases, the cardiovascular system. Reactions can range from mild to severe, including the potentially life-threatening condition known as anaphylaxis. Symptoms typically appear within minutes to several hours after eating the food to which you are allergic. A person with a food allergy cannot tolerate even small amounts of the culprit food, as is the case with peanuts. Mild symptoms may include one or more of the following: hives (reddish, swollen, itchy areas on the skin), eczema (a persistent dry, itchy rash), redness of the skin or around the eyes, nausea or vomiting, diarrhea, stomach pain, nasal congestion or a runny nose, sneezing, slight, dry cough, odd taste in mouth, uterine contractions 136 Severe symptoms may include one or more of the following: obstructive swelling of the lips, tongue, and/or throat, trouble swallowing, shortness of breath or wheezing, turning blue, drop in blood pressure, loss of consciousness, chest pain. The first step an allergist will take to diagnose a food allergy is a thorough medical history. The allergist will ask questions to determine if food allergy may be causing your symptoms and to identify the culprit food(s), and will then perform a physical exam. Next, the allergist may conduct tests to help identify a food allergy. These tests may include: Skin prick test Blood test Oral food challenge Trial elimination diet Several factors make diagnosis difficult. The reaction may depend on the amount of food consumed, the presence of other foods that can slow digestion, and medications such as antihistamines that may hide reactions. The proteins -- the antigens within the food or drink that cause the allergy -- may be altered by cooking or processing in some way. The antigens may be in only part of the food, such as the skin of an apple. Some are present only at a particular stage of ripeness. The treatment or management of IgE-mediated food allergies can be approached in two different ways. First, allergic reactions can be treated pharmacologically to resolve the symptoms. But, second and preferably, the avoidance of the allergenic food(s) will prevent the occurrence of allergic reactions. For patients at risk of experiencing a severe reaction (anaphylaxis), epinephrine is prescribed. Epinephrine is the only medication that can reverse the symptoms of anaphylaxis. From 3 percent to 8 percent of children have reactions to some foods. Only 1 percent to 2 percent have true food allergies. Some children seem to grow out of their sensitivity to certain foods, often by age 4. Allergies to peanuts, tree nuts and shellfish usually do not go away, though. From 1 percent to 2 percent of adults have true food allergies. But people of any age can have sudden allergic reactions to a food that had previously not been a problem for them. http://www.aafa.org/display.cfm?id=9&sub=20&cont=286 http://www.foodallergy.org/diagnosis-and-testing FOOD ALLERGY Onset of symptoms Amount of food eaten Causes Symptoms 137 Severity of symptoms Diagnosis Treatment Prevalence in population LISTENING 5.4.4 Type-1 Hypersensitivity: IgE mediated food allergy (L) Listen to the recording and complete the text with the missing words. Source: https://www.youtube.com/watch?v=gafekFEbUg4 Some people develop an allergic reaction or hypersensitivity when exposed to substances such as dust, pollens, 1. ____________________ or penicillin. This hypersensitivity is mediated by IgE. Sensitization occurs when the antigen makes contact with some part of the body. The antigen is taken up, processed by 2. ____________________ and presented on a class II MHC to T-helper cells. Tissues under the mucous membranes are rich in B cells committed to IgE production and IgE producing cells are more abundant in person 3. ____________________ to allergies. The T-helper 138 cells produce cytokines which stimulate these B cells to 4. ____________________ and differentiate into IgE producing plasma cells. As IgE is produced in different parts of the body, the IgE molecules attached via their constant regions to 5. ____________________ on nearby mast cells. Mast cells contain granules packed with chemicals that 6. ____________________ a hypersensitivity response. Once attached to the IgE, molecules can survive for many weeks. The individual is now sensitized to the antigen. When exposed to the antigen for a second time, the antigen binds to the IgE antibodies on the mast cells. To trigger a response, two cell bound IgE molecules must react with a specific antigen. Within seconds of the reaction, the mast cell 7. _____________________ histamine and other mediators of the inflammatory response from the granules triggering a variety of symptoms: capillary dilation, 8. _____________________, mucus secretion, pain, itching. SPEAKING 5.4.5. Communicating with the patient (S) 1. Read the following sentences and write D after the ones that are said by a doctor or P said by a patient. Your test results have come in. _____ I'm afraid the prognosis isn't good. _____ You have a long road to recovery. _____ I don't understand what this means. _____ Am I going to need surgery? _____ We have several options to discuss. _____ When will the tests results come in? _____ How long do I have to stay in the hospital? _____ The blood test came back negative. _____ The transfusion was a success. _____ It looks like you're ready to go home. _____ Is it good news or bad? _____ I'd like to keep you here over night. _____ We'll know more in a few days. _____ You're not in the clear yet. _____ We've ruled out diabetes. _____ I'm hoping to get to the bottom of this soon. _____ What is the success rate? _____ Are they going to run more tests? _____ Is this a common problem for people my age? _____ I'm going to get a second opinion. _____ 139 2. Read the sample conversation and answer the questions below. Doctor: Patient: Doctor: Patient: Doctor: Patient: Doctor: Patient: Doctor: Patient: Doctor: Patient: Doctor: Patient: Doctor: Patient: Doctor: Hi Jessica. How are you feeling today? A bit better. That's good to hear. Are you still feeling nauseous? No, I haven't felt sick to my stomach since you switched my medication. Great. Say, your test results came in this morning. It's about time. Is it good news or bad? I guess it's a bit of both. Which do you want first? Let's get the bad news over with. Okay. It looks like you're going to need surgery to remove the tumour from your leg. After the operation you're going to have to stay off your feet for at least three weeks. That means no soccer. I was afraid you were going to say that. Now for the good news. The biopsy shows that the tumour is benign, which means it's not cancerous. We're going to take it out anyway just to be on the safe side. Wow, that's a load off my mind. Thanks Doctor. Don't get too excited. We still need to get to the bottom of all of this weight loss. I've probably just been so worried about this stupid lump. These things often are stress related, but we're still going to do a few blood tests just to rule a few things out. Things like what? Cancer? Actually, I'm thinking more along the lines of a food allergy. 1) Why did the woman have to switch medication? 2) What bad news does the doctor give the patient? 3) What medical procedure did the patient already undergo? http://www.englishclub.com/english-for-work/medical-diagnosis.htm 3. With a partner, act out the roles below. Student A: Miután tejtermékeket fogyaszt erős hasi görcs, hasmenés, hasfájás, puffadás jelentkezik Önnél. A tünetek fél-2 óra elteltével jelentkeznek. Most az orvosához fordul tanácsért. Mondja el a panaszát és érdeklődjön a lehetséges vizsgálatok, kezelések felől. Student B: Ön orvos. Betege laktóz érzékenységre utaló panaszokról számol be. Utalja be a megfelelő vizsgálatokra, és amíg az eredmények meg nem érkeznek, javasoljon diétát. Kérje meg betegét, hogy vezessen naplót arról, amit eszik, megjelölve a tünetek jelentkezését, súlyosságát. Mondja el, hogyan lehet a tejtermékeket helyettesíteni, hol lehet ilyen termékeket beszerezni. * 140 *Get a Diagnosis: to keep a diary of the foods you eat Hydrogen Breath Test: Normally, people have very little hydrogen in their breath. If your body doesn't digest lactose, though, hydrogen builds in your intestines, and after a while it's in your breath. This test measures how much hydrogen is in your breath after you have a lactose-loaded drink several times in a few hours. Lactose Tolerance Test: When your body breaks down lactose, it releases sugar into your blood. This test shows how much sugar is in your blood. http://www.webmd.com/digestive-disorders/lactose-intolerance-14/diagnosing READING 5.4.6 Celiac disease (R) Read the text below and complete it with the missing words from the box. gluten-free grow out ingestion epilepsy dermatitis herpetiformis gluten predisposed villi Celiac disease is an autoimmune disorder that can occur in genetically 1. ____________________ people where the 2. ____________________ of gluten leads to damage in the small intestine. When eaten by someone with the disease, gluten damages the small finger-like protrusions, or 3. ____________________, that make up the lining of our small intestines (see illustration below). Celiac disease can develop at any age after people start eating foods or medicines that contain 4. ____________________. Left untreated, celiac disease can lead to additional serious health problems. These include the development of other autoimmune disorders like Type I diabetes and multiple sclerosis (MS), 5. ____________________ (an itchy skin rash), anemia, osteoporosis, infertility and miscarriage, neurological conditions like 6. ____________________and migraines, short stature, and intestinal cancers. Currently, the only treatment for celiac disease is lifelong adherence to a strict 7. ____________________ diet. The amount of time it takes to feel better after going gluten-free is different for every person. Some people feel the results right away, but others need weeks or months to feel results. Unfortunately, it is not possible to 8. ____________________ celiac disease. 141 http://celiac.org/celiac-disease/what-is-celiac-disease/ http://archive.constantcontact.com/fs141/1102093008750/archive/1114178442128.html SPEAKING 5.4.7 Celiac disease: giving advice (S) With a partner, act out the roles below. Student A: You are a doctor. Student B’s child has been diagnosed with celiac disease. Talk to him/her about: the disease long term health effects where to buy gluten-free products the importance of avoidance diet*, grains that have gluten Student A should have a gluten test himself/herself Student B: Your child has been diagnosed with celiac disease. You consult your doctor about: the disease the diet (which grains have gluten vs. safe grains) where to buy such products how much gluten is too much should you be tested yourself if the disease can be outgrown (*people with celiac disease can handle up to 10 milligrams of gluten — the equivalent of 1/8th of a teaspoon of flour without any harm even on a daily basis, more than that on a daily basis can add up 142 causing severe diarrhea and vomiting, and increase villous atrophy. Wheat, barley, and rye should be avoided.) http://celiacdisease.about.com/od/PreventingCrossContamination/f/How-Much-Gluten-Can-Make-MeSick.htm 5.5. AIDS SPEAKING 5.5.1 FAQ (S) In small groups, discuss the following questions. 1) What does the abbreviation AIDS stand for? 2) What causes AIDS? 3) What is HIV? 4) What does HIV stand for? 5) How do you get HIV or AIDS? Look at the pictures. They can give you clues. http://aids.gov/hiv-aids-basics/hiv-aids-101/how-you-get-hiv-aids/ 6) How long does it take HIV to cause AIDS? 7) What is the connection between HIV and other sexually transmitted diseases? 8) What means would you use in order to minimize the risk of AIDS? 9) How many people have HIV and AIDS? 10) If a pregnant woman is HIV+, the baby will be HIV+ too. Is it true or false? 11) Can mosquitoes transmit the HIV virus? 12) When is World AIDS Day observed? http://www.aids.org/topics/aids-faqs/ 143 VOCABULARY DEVELOPMENT 5.5.2 Frequent words in connection with AIDS (V) Find the matching pairs. Write the correct numbers into the table below. a b c deficiency needle breastfeed 1 2 3 d e f transmit saliva stage 4 5 6 g lesion 7 h affect 8 i motor loss 9 j dementia 10 a b c d a separate part that a process, etc. is divided into to attack somebody or a part of the body a serious mental disorder caused by brain disease or injury, that affects the ability to think, remember and behave normally the state of not having something that is essential it is a disorder that affects the ability to move a very thin, pointed piece of steel used on the end of a syringe for putting a drug into somebody's body, or for taking blood out of it the liquid that is produced in your mouth that helps you to swallow food when a woman feeds her baby with milk from her breasts damage to the skin or part of the body caused by injury or by illness to pass something from one person to another e f g h i j LISTENING 5.5.3 Everything you need to know about AIDS (L) Listen to the recording about AIDS and complete the sentences with the missing information. The lines indicate the number of words missing. Source: https://www.youtube.com/watch?v=rv0yIICeg-E AIDS stands for ’Acquired Immune Deficiency Syndrome’, which means deficient immune system. You get AIDS after becoming infected with the HIV virus. You get infected with the virus by unsafe sex, 1. __________ __________ __________ of an infected person, for example by using a contaminated injection needle. From mother to child during 2. _______________, childbirth or breastfeeding. Because the virus is transmitted through: blood, sperm, vaginal fluids, pre-seminal fluids,3. ________________. You don’t have the risk of becoming infected with the virus by saliva or shaking hands. When you have HIV virus, but aren’t symptomatic yet, you are ’sero-positive’. That means that there are HIV 4. __________ __________ ____________ __________. You don’t need to have any signs of disease yet. An HIV infection passes through four stages. In the first stage, the body can show signs of disease like 5. __________ __________ and swollen glands, 144 while some people, who are infected, remain asymptomatic in the first stage. In the second stage, recurring 6. __________ infections, skin, mouth, and genital lesions often occur. In the third stage, you may have complaints like prolonged diarrhea, excessive 7. __________ __________, tuberculosis in the lungs, and other serious infections like meningitis. Finally, besides serious infections, the nervous system may be affected in the fourth stage, which can result in motor loss or AIDS related dementia. It may take 8. ______ _______ ______ ______ before you know that you have got AIDS. This is because it sometimes takes longer for symptoms to occur. HIV and AIDS can be treated with 9. ___________ , but can’t be cured. Antiretrovirals slow down the multiplication of the virus, but doesn’t kill it. To support the treatment, AIDS patients often get medications to 10. ___________ the immune system and fight against infections. You can prevent AIDS by having safe sex and using clean needles. SPEAKING 5.5.4 Talking about AIDS (S) With the help of the prompts talk about AIDS. meaning of AIDS/HIV route of transmission risk groups early symptoms stages treatment prevention 145 5.6 VOCABULARY animal dander atrophy basophil converge crustacean define dilation extracellular fluid food challenge go awry granule hub induce ingestion insulation lupus lymph lymphocytes lymphoid mast cell moiety neutrophil obstructive optic nerve phagocytosis platelet precursor prevalence prick progenitor proliferate serous susceptible swirling thymus uterine állati szőr sorvadás bazofil összefut héjas állat korlátoz, határt szab tágulás extracelluláris folyadék ételpróba, ételterhelés fonákul üt ki, rosszul megy granula, szemcse csomópont indukál, előidéz fogyasztás, elfogyasztás szigetelés, szigetelőanyag lupus nyirok limfociták nyirokhízósejt felerész neutrophil, neutrophil leukocyta obstruktív, gátló, akadályozó látóideg fagocitózis trombocita, vérlemezke prekurzor, elővegyület előfordulás gyakorisága, prevalencia szúrás ős, előd osztódással szaporodik, osztódik savós hajlamos, fogékony örvénylő csecsemőmirigy méh- 146 147