CALIFORNIA, SANTA CRUZ UNIVERSITY OF CALIFORNIA, SANTA CRUZ 1156 High Street Santa Cruz, CA 95064 TEL: (831) 459-3155 FAX: (831) 459-2935 Web: www.chemistry.ucsc.edu Email: olof@chemistry.ucsc.edu Department of Chemistry and Biochemistry Olof Einarsdottir, Professor and Chair. Degrees Offered: B.A, B.S, M.S, Ph.D. Fields of Specialization: Organic, Physical and Inorganic Chemistry and Biochemistry. Interdisciplinary Program: Center for the Molecular Biology of RNA (Department of Molecular, Cell & Developmental Biology), Center for Biomolecular Science and Engineering (Department of Computer Science, Department of Molecular and Cell & Developmental Biology). ANDERSON, ROGER W. (b.1943) Professor. B.A, 1964, Carleton College; M.A, 1965, Harvard University; Ph.D, 1968, Harvard University. Chemical Physics; Theoretical Chemistry. Achromatic lenses for polar molecules; reaction mechanisms of light activated chemical vapor deposition and homogeneous nucleation; quantum calculations of energy transfer and reactions; small angle x-ray scattering by fractal clusters. TEL: (831) 459-2854 FAX: (831) 459-2935 Web: chemistry.ucsc.edu/faculty/anderson.html Email: anderso@chemistry.ucsc.edu anderso@ucsc.edu No publication information submitted for this edition. 1 infection in a phase 3 HIV-1 preventive vaccine trial, J. Infect. Dis, 191, 666-667 (2005). P. B. Gilbert, M. L. Peterson, D. Follmann, M. G. Hudgens, D. P. Francis, M. Gurwith, W. L. Heyward, D. V. Jobes, V. Popovic, S. G. Self, F. Sinangil, D. Burke and P. W. Berman, HIV-1 virologic and immunologic progression and initiation of antiretroviral therapy among HIV-1-infected subjects in a trial of the efficacy of recombinant glycoprotein 120 vaccine, J. Infect. Dis, 192, 974-983 (2005). D. V. Jobes, M. Daoust, V. Nguyen, A. Padua, S. Michele, M. D. Lock, A. Chen, F. Sinangil and P. W. Berman, High incidence of unusual cysteine variants in gp120 envelope proteins from early HIV Type 1 infections from a phase 3 vaccine efficacy trial, AIDS Res. Hum. Retroviruses, 22, 1014-1021 (2006). D. V. Jobes, M. Daoust, V. Nguyen, A. Padua, S. Michele, M. D. Lock, A. Chen, F. Sinangil and P. W. Berman, Longitudinal population analysis of dual infection with recombination in two strains of HIV type 1 subtype B in an individual from a phase 3 HIV vaccine efficacy trial, AIDS Res. Hum. Retroviruses, 22, 968-978 (2006). P. Pitisuttithum, P. Gilbert, W. Gurwith, W. Heyward, M. Martin, D. van Griensven, D. Hu, J. W. Tappero and K. Choopanya, Randomized, double-blind, placebo-controlled efficacy trial of a bivalent recombinant glycoprotein 120 HIV-1 vaccine among injection drug users in Bangkok, Thailand, J. Infect. Dis, 194, 1661-1671 (2006). BERNASCONI, CLAUDE F. (b.1939) Professor. M.S, 1963, Swiss Fed. Inst. Technology; Ph.D, 1965, Swiss Fed. Inst. Technology. Research Associate, 19651966, Swiss Federal Institute of Technology (ETH), Zürich; Research Associate, 1966-1967, Max-Planck Institute for Physical Chemistry, Göttingen. Organometallic Chemistry; Physical Organic Chemistry. Physical and mechanistic organic chemistry; proton transfers; nucleophilic addition to olefins and metal carbene complexes; nucleophilic vinylic substitution; ab initio calculations. TEL: (831) 459-2035 FAX: (831) 459-2935 Web: www.chemistry.ucsc.edu/faculty/bernasconi.html Email: bernasconi@chemistry.ucsc.edu Nicolas Winter and Ilan Benjamin, Molecular dynamics study of a model SN1 dissociation reaction at liquid/liquid interfaces: effect of liquid polarity, Isr. J. Chem, 47, 115-127 (2007). Ilan Benjamin, Solute rotational dynamics at the water liquid/vapor interface, J. Chem. Phys, 127, 204712/1-204712/ 11 (2007). Ilan Benjamin, Empirical valence bond model of an SN2 reaction in polar and nonpolar solvents, J. Chem. Phys, 129, 074508/1-074508/11 (2008). Ilan Benjamin, Structure and Dynamics of Hydrated Ions in a Water-Immiscible Organic Solvent, J. Phys. Chem. B, 112, 15801-15806 (2008). Nicolas Winter, John Vieceli and Ilan Benjamin, Hydrogen-Bond Structure and Dynamics at the Interface between Water and Carboxylic Acid-Functionalized Self-Assembled Monolayers, J. Phys. Chem. B, 112, 227-231 (2008). Ilan Benjamin, Solute orientational dynamics at the water/ carbon tetrachloride interface, J. Phys. Chem. C, 112, 89698975 (2008). Claude F. Bernasconi and Moises Perez-Lorenzo, Does Aromaticity in a Reaction Product Increase or Decrease the Intrinsic Barrier? Kinetics of the Reversible Deprotonation of Benzofuran-3(2H)-one and Benzothiophen-3(2H)-one, J. Am. Chem. Soc, 129, 2704-2712 (2007). Claude F. Bernasconi, Martin E. Zoloff Michoff, Rita H. De Rossi and Alejandro M. Granados, Kinetics of the Reactions of [p-Nitrophenoxy(phenyl)carbene]pentacarbonylchromium(0) with Aryloxide Ions, Hydroxide Ion, and Water in Aqueous Acetonitrile. Concerted or Stepwise?, J. Org. Chem, 72, 1285-1293 (2007). Claude F. Bernasconi, Shoshana D. Brown, Irina Eventova and Zvi Rappoport, Spectroscopic and Kinetic Evidence for an Accumulating Intermediate in an SNV Reaction with Amine Nucleophiles. Reaction of Methyl -Methylthio-␣-nitrocinnamate with Piperidine and Morpholine, J. Org. Chem, 72, 3302-3310 (2007). Claude F. Bernasconi, Moises Perez-Lorenzo and Shoshana D. Brown, Kinetics of the Deprotonation of Methyl nitroacetate by Amines: Unusually High Intrinsic Rate Constants for a Nitroalkane, J. Org. Chem, 72, 4416-4423 (2007). Claude F. Bernasconi, Moises Perez-Lorenzo and Sara J. Codding, Reactions of [Aryloxy(phenyl)carbene]pentacarbonylchromium(0) Complexes with Thiolate Ions. Decreasing Reactivity with Increasing Basicity of the Nucleophile, J. Org. Chem, 72, 9456-9463 (2007). Claude F. Bernasconi, Philip J. Wenzel and Mark L. Ragains, Proton Transfers in Aromatic and Antiaromatic Systems. How Aromatic or Antiaromatic Is the Transition State? An Ab Initio Study, J. Am. Chem. Soc, 130, 4934-4944 (2008). Miriam Karni, Claude F. Bernasconi and Zvi Rappoport, Role of Negative Hyperconjugation and Anomeric Effects in the Stabilization of the Intermediate in SNV Reactions, J. Org. Chem, 73, 2980-2994 (2008). BERMAN, PHILLIP W. (b.1948) Professor. A.B, BOGOMOLNI, ROBERTO A. (b.1942) Professor. 1971, UC Berkeley. Postdoctoral Fellowship, 19771981, The Salk Institute; Postdoctoral Fellowship, 19811982, UC San Francisco. Immunology; Virology. Development of products and methods for the diagnosis, prevention and treatment of infectious diseases, esp. HIV-1; analysis of the immune response to HIV-1 and the identification of epitopes recognized by broadly neutralizing antibodies; engineering cell lines for the large scale purification of recombinant glycoproteins. TEL: (831) 4593529 FAX: (831) 459-1970 Web: www.cbse.ucsc.edu/people/berman Email: pwb@soe.ucsc.edu Ph.D, 1972, University of California, Berkeley. Clinical Biochemist, 1964, University of Buenos Aires, Argentina, (professional degree in Pathology). Biophysics/Biophysical Chemistry; Photochemistry. Bacterial rhodopsin, structure and functional studies of retinal protein; pineal gland photoreceptor pigments, plant and microorganism blue-light receptors, flavoproteins and carotenoid pigments, and new time-resolved Raman and infrared techniques for detection of protein dynamics in the picoto-microsecond time scale. TEL: (831) 459-4294 FAX: (831) 459-2935 Web: www.chemistry.ucsc.edu/faculty/bogomolni.html Email: bogo@chemistry.ucsc.edu BENJAMIN, ILAN (b.1956) Professor. B.S, 1981, Hebrew University of Jerusalem, Israel; Ph.D, 1986, Hebrew University of Jerusalem, Israel. Weizmann Postdoctoral Fellowship, 1985-1987, University of Pennsylvania; Postdoctoral Fellowship, 1987-1989, University of California, San Diego. Computational Chemistry; Theoretical Chemistry. Chemical reaction dynamics in the condensed phase; molecular dynamics simulations and theory; application to liquid surfaces and interfaces. TEL: (831) 459-3152 FAX: (831) 459-2935 Web: www.chemistry.ucsc.edu/benjamin_i.html Email: benjamin@chemistry.ucsc.edu benjamin@ucsc.edu N. M. Flynn, D. N. Forthal, C. D. Harro, F. N. Judson, K. H. Mayer and M. F. Para, Placebo-controlled phase 3 trial of a recombinant glycoprotein 120 vaccine to prevent HIV-1 infection, J. Infect. Dis, 191, 654-665 (2005). P. B. Gilbert, M. L. Peterson, D. Follmann, M. G. Hudgens, D. P. Francis, M. Gurwith, W. L. Heyward, D. V. Jobes, V. Popovic, S. G. Self, F. Sinangil, D. Burke and P. W. Berman, Correlation between immunologic responses to a recombinant glycoprotein 120 vaccine and incidence of HIV- Eefei Chen, Trevor E. Swartz, Roberto A. Bogomolni and David S. Kliger, A LOV Story: The Signaling State of the Phot1 LOV2 Photocycle Involves Chromophore-Triggered Protein Structure Relaxation, As Probed by Far-UV TimeResolved Optical Rotatory Dispersion Spectroscopy, Biochemistry, 46, 4619-4624 (2007). John M. Christie, Stephanie B. Corchnoy, Trevor E. Swartz, Mark Hokenson, In-Seob Han, Winslow R. Briggs 1 and Roberto A. Bogomolni, Steric Interactions Stabilize the Signaling State of the LOV2 Domain of Phototropin 1, Biochemistry, 46, 9310-9319 (2007). Winslow R. Briggs, Tong-Seung Tseng, Hae-Young Cho, Trevor E. Swartz, Stuart Sullivan, Roberto A. Bogomolni, Eirini Kaiserli and John M. Christie, Phototropins and their LOV domains: versatile plant blue-light receptors, J. Integr. Plant Biol, 49, 4-10 (2007). Trevor E. Swartz, Tong-Seung Tseng, Marcus A. Frederickson, Gaston Paris, Diego J. Comerci, Gireesh Rajashekara, Jung-Gun Kim, Mary Beth Mudgett, Gary A. Splitter, Rodolfo A. Ugalde, Fernando A. Goldbaum, Winslow R. Briggs and Roberto A. Bogomolni, Blue-Light-Activated Histidine Kinases: Two-Component Sensors in Bacteria, Science (Washington, DC, U. S.), 317, 1090-1093 (2007). BRASLAU, REBECCA (b.1959) Associate Professor. B.A, 1982, Reed College; Ph.D, 1989, University of Wisconsin, Madison. Postdoctoral Fellowship with Dr. Bernd Giese, 1989-1991, Institut für Organische Chemie, Universität Basel, Switzerland. Materials Chemistry; Organic Chemistry. Organic synthesis, development of new synthetic methodologies, organic free radical chemistry, nitroxides, profluorescent nitroxides, nitroxide-mediated free radical polymerization, telechelic polymers; development of sensors and designed materials for biomedical and nanotechnological applications. TEL: (831) 4593087 FAX: (831) 459-2935 Web: www.chemistry.ucsc.edu/faculty/braslau.html Email: braslau@chemistry.ucsc.edu Jianfei Jiang, Igor Kurnikov, Natalia A. Belikova, Jingbo Xiao, Qing Zhao, Andrew A. Amoscato, Rebecca Braslau, Armido Studer, Mitchell P. Fink, Joel S. Greenberger, Peter Wipf and Valerian E. Kagan, Structural requirements for optimized delivery, inhibition of oxidative stress, and antiapoptotic activity of targeted nitroxides, J. Pharmacol. Exp. Ther, 320, 1050-1060 (2007). Jean Ruehl and Rebecca Braslau, A bidirectional ATRPNMRP initiator: the effect of nitroxide size on the rate of nitroxide-mediated polymerization, J. Polym. Sci., Part A: Polym. Chem, 45, 2015-2025 (2007). Nicole L. Hill and Rebecca Braslau, Synthesis of arylethylfunctionalized N-alkoxyamine initiators and use in nitroxidemediated radical polymerization, J. Polym. Sci., Part A: Polym. Chem, 45, 2341-2349 (2007). Greg O’Bryan, Aaron Nilsen and Rebecca Braslau, Ketone Functionalized Nitroxides: Synthesis, Evaluation of N-Alkoxyamine Initiators, and Derivatization of Polymer Termini, Macromolecules (Washington, DC, U. S.), 40, 7848-7854 (2007). Jean Ruehl, Aaron Nilsen, Stephen Born, Praveen Thoniyot, Li-Ping Xu, Shaowei Chen and Rebecca Braslau, Nitroxide-mediated polymerization to form symmetrical ABA triblock copolymers from a bidirectional alkoxyamine initiator, Polymer, 48, 2564-2571 (2007). J. Ruehl, N. Ningnuek, T. Thongpaisanwong and R. Braslau, Cyclic alkoxyamines for nitroxide mediated radical polymerization, J. Polym. Sci., Part A: Polym. Chem, 49, 80498069 (2008). Jean Ruehl, Nicole L. Hill, Eric D. Walter, Glenn Millhauser and Rebecca Braslau, A Proximal Bisnitroxide Initiator: Studies in Low-Temperature Nitroxide-Mediated Polymerizations, Macromolecules (Washington, DC, U. S.), 41, 19721982 (2008). G. O’Bryan, N. Ningnuek and R. Braslau, Cyclization of ␣- heterotelechelic polystyrene prepared by nitroxide-mediated radical polymerization, Polymer, 49, 5241-5248 (2008). J. Ruehl, C. Morimoto, D. J. Stevens, G. Millhauser and R. Braslau, Carboxylic acid and hydroxy-functionalized alkoxyamine initiators for nitroxide mediated radical polymerization, React. Funct. Polym, 68, 1563-1577 (2008). N. L. Hill, J. L. Jarvis, F. Pettersson and R. Braslau, Synthesis of thiol-derivatized initiators for nitroxide-mediated radical polymerization: Reversible disulfide formation, React. Funct. Polym, 68, 361-368 (2008). Wilson Chau, Rushia Turner and Rebecca Braslau, Ketone -functionalization of polymers prepared by nitroxide-mediated polymerization via addition to a benzyl enol ether, React. Funct. Polym, 68, 396-405 (2008). MariEllen Cottman, Optimization of a fluorescent detection method for urushiol. (M) Wilson Chau, Functionalization of polymers prepared by nitroxide mediated polymerization. (M) Gregory J. O’Bryan, Preparation of telechelic polymers via nitroxide mediated polymerization. (D) Jean K. Ruehl, Alkoxyamine initiators for nitroxide mediated radical polymerization: Synthesis, characterization, and applications. (D) Nicole Hill, Development of novel functionalized bis-nitroxide initiators for the preparation of designed polymers. (D) BRULAND, KENNETH (b.1946) Professor. B.A, 1968, Western Washington State College; Ph.D, 1974, University of California, San Diego. Marine Science. Marine geochemistry of trace elements and radionuclides. TEL: (831) 459-4587 FAX: (831) 459-4882 Web: oceansci.ucsc.edu/faculty/bruland.html 2 CALIFORNIA, SANTA CRUZ Email: bruland@ucsc.edu F. J. Black, K. W. Bruland and A. R. Flegal, Competing ligand exchange-solid phase extraction method for the determination of the complexation of dissolved inorganic mercury (II) in natural waters, Anal. Chim. Acta, 598, 318-333 (2007). K. Johnson, E. Boyle, K. Bruland, K. Coale, C. Measures, J. Moffett, A. Aguilar-Islas, K. Barbeau, B. Bergquist, A. Bowie, K. Buck, Y. Cai, Z. Chase, J. Cullen, T. Doi, V. Elrod, S. Fitzwater, M. Gordon, A. King, P. Laan, L. Baquer, W. Landing, M. Lohan, J. Mendez, A. Milne, H. Obata, L. Ossiander, J. Plant, G. Sarthou, P. Sedwick, G. Smith, B. Sohst, S. Tanner, S. Van den Berg and J. Wu, Developing standards for dissolved iron in seawater, EOS, 8, 131-132 (2007). K. N. Buck and K. W. Bruland, The physico-chemical speciation of dissolved iron in the Bering Sea, Alaska, Limnology and Oceanography, 52, 1800-1808 (2007). K. N. Buck, M. C. Lohan, C. J. M. Berger and K. W. Bruland, Dissolved iron speciation in two distinct river plumes and an estuary: Implications for riverine iron supply, Limnology and Oceanography, 52, 843-855 (2007). M. P. Hurst and K. W. Bruland, An investigation into the exchange of iron and zinc between soluble, colloidal, and particulate size-fractions in shelf waters using low-abundance isotopes as tracers in shipboard incubation experiments, Marine Chemistry, 103, 211-226 (2007). A. M. Aguilar-Islas, M. P. Hurst, K. N. Buck, B. Sohst, G. J. Smith, M. C. Lohan and K. W. Bruland, Micro- and macronutrients in the southeastern Bering Sea: Insight into ironreplete and iron-deplete regimes, Progress in Oceanography, 73, 99-126 (2007). M. C. Lohan and K. W. Bruland, Elevated Fe(II) and dissolved Fe in hypoxic shelf waters off Oregon and Washington: An enhanced source of iron to coastal upwelling regimes, Environ. Sci, Technol, 42, 6461-6468 (2008). M. P. Hurst and K. W. Bruland, The effects of the San Francisco Bay plume on trace metal and nutrient distributions in the Gulf of the Farallones, Geochimica and Cosmochimica, 72, 395-411 (2008). K. W. Bruland, M. C. Lohan, A. M. Aguilar-Islas, G. J. Smith, B. Sohst and A. Baptista, Factors influencing the chemistry of the near-field Columbia River plume: nitrate, silicic acid, dissolved Fe and dissolved Mn, J. Geophys. Res.: Oceans, 113 (2008). C. J. M. Berger, S. M. Lippiatt, M. G. Lawrence and K. W. Bruland, The application of a chemical leach technique for estimating labile particulate aluminum, iron, and manganese in the Columbia River plume and coastal waters off Oregon and Washington, J. Geophys. Res.: Oceans, 113 (2008). M. T. Brown and K. W. Bruland, An improved flow injection analysis method for the determination of dissolved aluminum in seawater, Limnology and Oceanography: Methods, 6, 87-95 (2008). Ana Aguilar-Islas, Sources and processes controlling dissolved manganese in the eastern boundary regions of the North Pacific and Bering Sea, and an insight into the iron-replete and iron-deplete regimes of the Bering Sea. (D) CAMPS, MANEL (b.1970) Assistant Professor. M.S, 1994, Autonomous University Barcelona; Ph.D, 2001, Stanford University. Research Fellow, 2001-2004, Univ. of Washington; Acting Instructor, 2004-2007, Univ. of Washington. Biomedical Engineering. Study of biological consequences of mutation, with emphasis on adaptation (ie generation of novel biochemical activities). Directed enzyme evolution of extended-spectrum beta-lactamase. Role of DNA polymerase I in DNA repair and ColE1 plasmid replication. TEL: (831) 459-5396 FAX: (831) 459-3524 Web: www.etox.ucsc.edu/fac_res/camps_lab.html Email: mcamps@ucsc.edu Manel Camps and Lawrence A. Loeb, Critical role of Rloops in processing replication blocks, Frontiers in Bioscience, 10, 689-698 (2005). Manel Camps, Asael Herman, Ern Loh and Lawrence A. Loeb, Genetic constraints on protein evolution, Crit. Rev. Biochem. Mol. Biol, 42, 313-326 (2007). Tam T. Van, Seon-Kyeong Kim, Manel Camps, John C. Boothroyd and Laura J. Knoll, The BSR4 protein is up-regulated in Toxoplasma gondii bradyzoites, however the dominant surface antigen recognized by the P36 monoclonal antibody is SRS9, Int. J. Parasitol, 37, 877-885 (2007). CHEN, SHAOWEI (b.1968) Associate Professor. B.S, 1991, University of Science and Technology of China; M.S, 1993, Cornell University; Ph.D, 1996, Cornell University. Research Associate, 1996-1998, University of North Carolina. Chapel Hill. Electrochemistry; Materials Chemistry. Synthesis, characterization and manipulation of novel functional nanomaterials, their long-range ordered assemblies and related nanoscale electron-transfer, applications in fuel cells, photovoltaics and electronic devices. TEL: (831) 459-5841 FAX: (831) 459-2935 Web: www.chemistry.ucsc.edu/faculty/chen.html Email: schen@chemistry.ucsc.edu Sulolit Pradhan, Li-Ping Xu and Shaowei Chen, Janus nanoparticles by interfacial engineering, Adv. Funct. Mater, 17, 2385 (2007). Wei Chen, Debraj Ghosh, Jia Sun, Moony C. Tong, Fengjun Deng and Shaowei Chen, Dithiocarbamate-protected ruthenium nanoparticles: Synthesis, spectroscopy, electrochemistry and STM studies, Electrochim. Acta, 53, 1150-1156 (2007). Sulolit Pradhan, Debraj Ghosh, Li-Ping Xu and Shaowei Chen, Interparticle Charge Transfer Mediated by - Stacking of Aromatic Moieties, J. Am. Chem. Soc, 129, 1062210623 (2007). Shaowei Chen, Discrete charge transfer in nanoparticle solid films, J. Mater. Chem, 17, 4115-4121 (2007). Wei Chen, Jaemin Kim, Li-Ping Xu, Shouheng Sun and Shaowei Chen, Langmuir-Blodgett Thin Films of Fe20Pt80 Nanoparticles for the Electrocatalytic Oxidation of Formic Acid, J. Phys. Chem. C, 111, 13452-13459 (2007). Wei Chen, Jaemin Kim, Shouheng Sun and Shaowei Chen, Composition Effects of FePt Alloy Nanoparticles on the Electro-Oxidation of Formic Acid, Langmuir, 23, 1130311310 (2007). Li-Ping Xu, Sulolit Pradhan and Shaowei Chen, Adhesion Force Studies of Janus Nanoparticles, Langmuir, 23, 85448548 (2007). Fengjun Deng and Shaowei Chen, Electrochemical Quartz Crystal Microbalance Studies of the Rectified Quantized Charging of Gold Nanoparticle Multilayers, Langmuir, 23, 936-941 (2007). Jean Ruehl, Aaron Nilsen, Stephen Born, Praveen Thoniyot, Li-Ping Xu, Shaowei Chen and Rebecca Braslau, Nitroxide-mediated polymerization to form symmetrical ABA triblock copolymers from a bidirectional alkoxyamine initiator, Polymer, 48, 2564-2571 (2007). Shaowei Chen, Li-Ping Xu, Sulolit Pradhan and Wei Chen, Temperature-modulated scanning tunneling spectroscopy of gold nanoparticle dropcast films, Solid State Commun, 144, 124-127 (2007). Eric P. Lee, Zhenmeng Peng, Wei Chen, Shaowei Chen, Hong Yang and Younan Xia, Electrocatalytic Properties of Pt Nanowires Supported on Pt and W Gauzes, ACS Nano, 2, 2167-2173 (2008). Chao Shi, He Yan, Claire Gu, Debraj Ghosh, Leo Seballos, Shaowei Chen, Jin Z. Zhang and Bin Chen, A double substrate “sandwich” structure for fiber surface enhanced Raman scattering detection, Appl. Phys. Lett, 92, 103107/1-103107/3 (2008). Chao Shi, Chao Lu, Claire Gu, Lei Tian, Rebecca Newhouse, Shaowei Chen and Jin Z. Zhang, Inner wall coating hollow core waveguide sensor based on double substrate surface enhanced raman scattering, Appl. Phys. Lett, 93, 153101 (2008). Debraj Ghosh, Sulolit Pradhan, Wei Chen and Shaowei Chen, Titanium Nanoparticles Stabilized by Ti-C Covalent Bonds, Chem. Mater, 20, 1248-1250 (2008). Debraj Ghosh and Shaowei Chen, Solid-state electronic conductivity of ruthenium nanoparticles passivated by metalcarbon covalent bonds, Chem. Phys. Lett, 465, 115 (2008). Wei Chen, Shaowei Chen, Feizhi Ding, Haobin Wang, Lauren E. Brown and Joseph P. Konopelski, NanoparticleMediated Intervalence Transfer, J. Am. Chem. Soc, 130, 12156-12162 (2008). Debraj Ghosh and Shaowei Chen, Palladium nanoparticles passivated by metal-carbon covalent linkages, J. Mater. Chem, 18, 755-762 (2008). Wei Chen, Debraj Ghosh and Shaowei Chen, Large-scale electrochemical synthesis of SnO2 nanoparticles, J. Mater. Sci, 43, 5291-5299 (2008). Tzarara Lopez-Luke, Abraham Wolcott, Li-ping Xu, Shaowei Chen, Zhenhai Wen, Jinghong Li, Elder De La Rosa and Jin Z. Zhang, Nitrogen-Doped and CdSe Quantum-DotSensitized Nanocrystalline TiO2 Films for Solar Energy Conversion Applications, J. Phys. Chem. C, 112, 1282-1292 (2008). Sulolit Pradhan, Shaowei Chen, Jing Zou and Susan M. Kauzlarich, Photoconductivity of Langmuir-Blodgett Monolayers of Silicon Nanoparticles, J. Phys. Chem. C, 112, 13292-13298 (2008). Wei Chen, Jaemin Kim, Shouheng Sun and Shaowei Chen, Electrocatalytic Reduction of Oxygen by FePt Alloy Nanoparticles, J. Phys. Chem. C, 112, 3891-3898 (2008). Sulolit Pradhan, Solid state charge transfer in nanoparticle solids. (D) CREWS, PHILLIP (b.1943) Professor. B.S, 1966, University of California, Los Angeles; Ph.D, 1969, University of California, Santa Barbara. NSF Postdoctoral Fellowship, 1969-1970, Princeton University. Natural Products Chemistry; Organic Chemistry. Application of nuclear magnetic resonance to organic structures marine natural products-structure determination of biologically important substances from marine macro- and microorganisms. TEL: (831) 459-2603 FAX: (831) 459-4197 Web: www.chemistry.ucsc.edu/faculty/crews.html Email: crewslab@chemistry.ucsc.edu phil@chemistry.ucsc.edu Joshua D. Deschamps, Jeffrey T. Gautschi, Stephanie Whitman, Tyler A. Johnson, Nadine C. Gassner, Phillip Crews and Theodore R. Holman, Discovery of platelet-type 12-human lipoxygenase selective inhibitors by high-throughput screening of structurally diverse libraries, Bioorg. Med. Chem, 15, 6900-6908 (2007). Xiaoyi Hu, Yongjun Dang, Karen Tenney, Phillip Crews, Chiawei W. Tsai, Katherine M. Sixt, Philip A. Cole and Jun O. Liu, Regulation of c-Src Nonreceptor Tyrosine Kinase Activity by Bengamide A through Inhibition of Methionine Aminopeptidases, Chem. Biol. (Cambridge, MA, U. S.), 14, 764-774 (2007). Tyler A. Johnson, Karen Tenney, Robert H. Cichewicz, Brandon I. Morinaka, Kimberly N. White, Taro Amagata, Balanehru Subramanian, Joseph Media, Susan L. Mooberry, Frederick A. Valeriote and Phillip Crews, Sponge-Derived Fijianolide Polyketide Class: Further Evaluation of Their Structural and Cytotoxicity Properties, J. Med. Chem, 50, 3795-3803 (2007). Sarah J. Robinson, Karen Tenney, Desiree F. Yee, Lizabeth Martinez, Joseph E. Media, Frederick A. Valeriote, Rob W. M. Van Soest and Phillip Crews, Probing the Bioactive Constituents from Chemotypes of the Sponge Psammocinia aff. bulbosa, J. Nat. Prod, 70, 1002-1009 (2007). Claudia M. Boot, Nadine C. Gassner, Jennifer E. Compton, Karen Tenney, Craig M. Tamble, R. Scott Lokey, Theodore R. Holman and Phillip Crews, Pinpointing pseurotins from a marine-derived Aspergillus as tools for chemical genetics using a synthetic lethality yeast screen, J. Nat. Prod, 70, 16721675 (2007). Sarah J. Robinson, Karen Tenney, Desiree F. Yee, Lizabeth Martinez, Joseph E. Media, Frederick A. Valeriote, Rob W. M. van Soest and Phillip Crews, Probing the bioactive constituents from chemotypes of the sponge Psammocinia aff. bulbosa. [Erratum to document cited in CA147:208190], J. Nat. Prod, 70, 1690 (2007). Paul Ralifo, Karen Tenney, Frederick A. Valeriote and Phillip Crews, A Distinctive Structural Twist in the Aminoimidazole Alkaloids from a Calcareous Marine Sponge: Isolation and Characterization of Leucosolenamines A and B, J. Nat. Prod, 70, 33-38 (2007). Nadine C. Gassner, Craig M. Tamble, Jonathan E. Bock, Naomi Cotton, Kimberly N. White, Karen Tenney, Robert P. St. Onge, Michael J. Proctor, Guri Giaever, Ronald W. Davis, Phillip Crews, Theodore R. Holman and R. Scott Lokey, Accelerating the Discovery of Biologically Active Small Molecules Using a High-Throughput Yeast Halo Assay, J. Nat. Prod, 70, 383-390 (2007). Ivette C. Pina, Kimberly N. White, Gustavo Cabrera, Eyleen Rivero and Phillip Crews, Bromopyrrole Carboxamide Biosynthetic Products from the Caribbean Sponge Agelas dispar, J. Nat. Prod, 70, 613-617 (2007). Brent K. Rubio, Rob W. M. Van Soest and Phillip Crews, Extending the Record of Meroditerpenes from Cacospongia Marine Sponges, J. Nat. Prod, 70, 628-631 (2007). Hou-Jin Li, Taro Amagata, Karen Tenney and Phillip Crews, Additional Scalarane Sesterterpenes from the Sponge Phyllospongia papyracea, J. Nat. Prod, 70, 802-807 (2007). Christopher J. Wegerski, Joshua Hammond, Karen Tenney, Teatulohi Matainaho and Phillip Crews, A Serendipitous Discovery of Isomotuporin-Containing Sponge Populations of Theonella swinhoei, J. Nat. Prod, 70, 89-94 (2007). Paul Ralifo, Laura Sanchez, Nadine C. Gassner, Karen Tenney, R. Scott Lokey, Theodore R. Holman, Frederick A. Valeriote and Phillip Crews, Pyrroloacridine Alkaloids from Plakortis quasiamphiaster: Structures and Bioactivity, J. Nat. Prod, 70, 95-99 (2007). Jeffrey T. Gautschi, Karen Tenney, Jennifer Compton and Phillip Crews, Chemical investigations of a deep water marine-derived fungus: Simple amino acid derivatives from an Arthrinium sp, Nat. Prod. Commun, 2, 541-546 (2007). Claudia M. Boot, Taro Amagata, Karen Tenney, Jennifer E. Compton, Halina Pietraszkiewicz, Frederick A. Valeriote and Phillip Crews, Four classes of structurally unusual peptides from two marine-derived fungi: Structures and bioactivities, Tetrahedron, 63, 9903-9914 (2007). Taro Amagata, Tyler A. Johnson, Robert H. Cichewicz, Karen Tenney, Susan L. Mooberry, Joseph Media, Matthew Edelstein, Frederick A. Valeriote and Phillip Crews, Interrogating the Bioactive Pharmacophore of the Latrunculin Chemotype by Investigating the Metabolites of Two Taxonomically Unrelated Sponges, J. Med. Chem, 51, 7234-7242 (2008). Brent K. Rubio, Sarah J. Robinson, Claudia E. Avalos, Frederick A. Valeriote, Nicole J. de Voogd and Phillip Crews, Revisiting the Sponge Sources, Stereostructure, and Biological Activity of Cyclocinamide A, J. Nat. Prod, 71, 1475-1478 (2008). Tyler A. Johnson, Taro Amagata, Allen G. Oliver, Karen Tenney, Frederick A. Valeriote and Phillip Crews, The Unexpected Isolation of CTP-431, a Novel Thiopyrone from the Sponge Cacospongia mycofijiensis, J. Org. Chem, 73, 7255-7259 (2008). Kimberly N. White, Taro Amagata, Allen G. Oliver, Karen Tenney, Philip J. Wenzel and Phillip Crews, Structure Revision of Spiroleucettadine, a Sponge Alkaloid with a Bicyclic Core Meager in H-Atoms, J. Org. Chem, 73, 8719-8722 (2008). Brent Rubio, Bioactive natural products for global health from Papua New Guinea marine sponges. (D) Christopher Wegerski, Chemistry under the sea: Secondary metabolites from marine sponges of Papua New Guinea. (D) DEAMER, DAVID W. (b.1939) Professor Emeritus. B.S, 1961, Duke University; Ph.D, 1965, Ohio State University. NIH Fellowship, 1965-1967, University of Cali- CALIFORNIA, SANTA CRUZ fornia, Berkeley. Biophysics/Biophysical Chemistry; Nanochemistry. Membrane biophysics. TEL: (831) 4595158 FAX: (831) 459-5158 Web: www.chemistry.ucsc.edu/faculty/deamer.html Email: deamer@chemistry.ucsc.edu Bernd R. T. Simoneit, Ahmed I. Rushdi and David W. Deamer, Abiotic formation of acylglycerols under simulated hydrothermal conditions and self-assembly properties of such lipid products, Adv. Space Res, 40, 1649-1656 (2007). David W. Deamer, Reay Dick, Wolfram Thiemann and Meir Shinitzky, Intrinsic asymmetries of amino acid enantiomers and their peptides: a possible role in the origin of biochirality, Chirality, 19, 751-763 (2007). Dongliang Yin, Evan J. Lunt, Mikhail I. Rudenko, David W. Deamer, Aaron R. Hawkins and Holger Schmidt, Planar optofluidic chip for single particle detection, manipulation, and analysis, Lab Chip, 7, 1171-1175 (2007). Seico Benner, Roger J. A. Chen, Noah A. Wilson, Robin Abu-Shumays, Nicholas Hurt, Kate R. Lieberman, David W. Deamer, William B. Dunbar and Mark Akeson, Sequencespecific detection of individual DNA polymerase complexes in real time using a nanopore, Nat. Nanotechnol, 2, 718-724 (2007). Helmut Zepik, Sudha Rajamani, Marie-Christine Maurel and David Deamer, Oligomerization of thioglutamic acid: Encapsulated reactions and lipid catalysis, Orig. Life Evol. Biosph, 37, 495-505 (2007). Robert M. Hazen and David W. Deamer, Hydrothermal Reactions of Pyruvic Acid: synthesis, Selection, and Self-Assembly of Amphiphilic Molecules, Origins Life Evol. Biospheres, 37, 143-152 (2007). Pierre-Alain Monnard, Andrej Luptak and David W. Deamer, Models of primitive cellular life: polymerases and templates in liposomes, Philos. Trans. R. Soc., B, 362, 17411750 (2007). Daniel Branton, David W. Deamer, Andre Marziali, Hagan Bayley, Steven A. Benner, Thomas Butler, Massimiliano Di Ventra, Slaven Garaj, Andrew Hibbs, Xiaohua Huang, Stevan B. Jovanovich, Predrag S. Krstic, Stuart Lindsay, Xinsheng Sean Ling, Carlos H. Mastrangelo, Amit Meller, John S. Oliver, Yuriy V. Pershin, J. Michael Ramsey, Robert Riehn, Gautam V. Soni, Vincent Tabard-Cossa, Meni Wanunu, Matthew Wiggin and Jeffery A. Schloss, The potential and challenges of nanopore sequencing, Nat. Biotechnol, 26, 11461153 (2008). Sudha Rajamani, Alexander Vlassov, Seico Benner, Amy Coombs, Felix Olasagasti and David Deamer, Lipid-assisted synthesis of RNA-like polymers from mononucleotides, Orig. Life Evol. Biosph, 38, 57-74 (2008). Trishool Namani and David W. Deamer, Stability of Model Membranes in Extreme Environments, Origins Life Evol. Biospheres, 38, 329-341 (2008). EINARSDOTTIR, OLOF (b.1956) Professor. B.S, 1980, University of Iceland, Reykjavik, Iceland; Ph.D, 1986, Colorado State University. Director’s Postdoctoral Fellow, 1986-1988, Los Alamos National Laboratory. Bioinorganic Chemistry; Biophysics/Biophysical Chemistry. Bioenergetics; heme-copper oxidases; the mechanism of electron transfer and proton translocation in respiration; exploration of photodissociable synthetic and biological O2 and NO carriers; synthesis and characterization of chemical analogs of the active site of cytochrome oxidase. TEL: (831) 459-3155 FAX: (831) 4592935 Web: www.chemistry.ucsc.edu/faculty/einarsdottir.html Email: olof@chemistry.ucsc.edu I. Szundi, J. Ray and Ó. Einarsdóttir, Flash photolysis of fully reduced and mixed-valence co-bound rhodobacter sphaeroides cytochrome c oxidase: Heme-heme spectral shifts, Biochemistry, 46, 12568-12578 (2007). K. N. White, I. Sen, I. Szundi, Y. R. Landaverry, L. E. Bria, J. P. Konopelski, M. M. Olmstead and Ó. Einarsdóttir, Synthesis and structural characterization of cross-linked histidine-phenol Cu(II)-complexes as models for the active site of cytochrome C oxidase, Chem. Commun, 31, 3252-3254 (2007). William J. McDonald and Olof Einarsdottir, Solvent Effects on the Vibrational Frequencies of the Phenolate Anion, the para-Cresolate Anion, and Their Radicals, J. Phys. Chem. A, 112, 11400-11413 (2008). FLEGAL, A. RUSSELL (b.1946) Professor. B.A, 1968, University of California Santa Barbara; M.S, 1976, California State University East Bay; Ph.D, 1979, Oregon State University. Research Fellow, 1979-1980, California Insitute of Technology. Environmental Chemistry; Toxicology. Biochemical cycles of trace elements, stable lead isotope geochemistry, mercury speciation and complexation. TEL: (831) 459-2093 FAX: (831) 459-3524 Web: www.etox.ucsc.edu/fac_res/flegal.html Email: flegal@metx.ucsc.edu Kuria Ndung’u, Sharon Hibdon and A. Russell Flegal, Lead in vinegar: determination and possible sources, Am. Lab. (Shelton, CT, U. S.), 39, 30,32,34 (2007). Frank J. Black, Kenneth W. Bruland and A. Russell Flegal, Competing ligand exchange-solid phase extraction method for the determination of the complexation of dissolved inor- 3 ganic mercury (II) in natural waters, Anal. Chim. Acta, 598, 318-333 (2007). Miguel Angel Huerta-Diaz, Ignacio Rivera-Duarte, Sergio A. Sanudo-Wilhelmy and A. Russell Flegal, Comparative distributions of size fractionated metals in pore waters sampled by in situ dialysis and whole-core sediment squeezing: implications for diffusive flux calculations, Appl. Geochem, 22, 2509-2525 (2007). Kristen N. Buck, John R. M. Ross, A. Russell Flegal and Kenneth W. Bruland, A review of total dissolved copper and its chemical speciation in San Francisco Bay, California, Environ. Res, 105, 5-19 (2007). Christopher H. Conaway, John R. M. Ross, Richard Looker, Robert P. Mason and A. Russell Flegal, Decadal mercury trends in San Francisco Estuary sediments, Environ. Res, 105, 53-66 (2007). Allison C. Luengen, Peter T. Raimondi and A. Russell Flegal, Contrasting biogeochemistry of six trace metals during the rise and decay of a spring phytoplankton bloom in San Francisco Bay, Limnol. Oceanogr, 52, 1112-1130 (2007). Celine Gallon, Jugdeep Aggarwal and A. Russell Flegal, Comparison of Mass Discrimination Correction Methods and Sample Introduction Systems for the Determination of Lead Isotopic Composition Using a Multicollector Inductively Coupled Plasma Mass Spectrometer, Anal. Chem. (Washington, DC, U. S.), 80, 8355-8363 (2008). Christopher H. Conaway, Frank J. Black, Thomas M. Grieb, Sujoy Roy and A. Russell Flegal, Mercury in the San Francisco Estuary, Rev. Environ. Contam. Toxicol, 194, 2954 (2008). and Theodore R. Holman, Substrate Specificity Changes for Human Reticulocyte and Epithelial 15-Lipoxygenases Reveal Allosteric Product Regulation, Biochemistry, 47, 7364-7375 (2008). Ritimukta Sarangi, Rosalie K. Hocking, Michael L. Neidig, Maurizio Benfatto, Theodore R. Holman, Edward I. Solomon, Keith O. Hodgson and Britt Hedman, Geometric Structure Determination of N694C Lipoxygenase: A Comparative Near-Edge X-Ray Absorption Spectroscopy and Extended XRay Absorption Fine Structure Study, Inorg. Chem. (Washington, DC, U. S.), 47, 11543-11550 (2008). Klaus van Leyen, Ken Arai, Guang Jin, Victor Kenyon, Bettina Gerstner, Paul A. Rosenberg, Theodore R. Holman and Eng H. Lo, Novel lipoxygenase inhibitors as neuroprotective reagents, J. Neurosci. Res, 86, 904-909 (2008). Allison Christine Luengen, Investigating the spring bloom in San Francisco Bay: Links between water chemistry, metal cycling, mercury speciation and phytoplankton community composition. (D) Frank J. Black, Method for investigating the complexation of inorganic mercury, and factors controlling the photo-degration of monomethyl mercury in natural waters. (D) Eefei Chen, Christina J. Abel, Robert A. Goldbeck and David S. Kliger, Non-Native Heme-Histidine Ligation Promotes Microsecond Time Scale Secondary Structure Formation in Reduced Horse Heart Cytochrome c, Biochemistry, 46, 12463-12472 (2007). Christina J. Abel, Robert A. Goldbeck, Ramil F. Latypov, Heinrich Roder and David S. Kliger, Conformational Equilibration Time of Unfolded Protein Chains and the Folding Speed Limit, Biochemistry, 46, 4090-4099 (2007). Eefei Chen, Trevor E. Swartz, Roberto A. Bogomolni and David S. Kliger, A LOV Story: The Signaling State of the Phot1 LOV2 Photocycle Involves Chromophore-Triggered Protein Structure Relaxation, As Probed by Far-UV TimeResolved Optical Rotatory Dispersion Spectroscopy, Biochemistry, 46, 4619-4624 (2007). Elsa C. Y. Yan, Jacqueline Epps, James W. Lewis, Istvan Szundi, Aditi Bhagat, Thomas P. Sakmar and David S. Kliger, Photointermediates of the Rhodopsin S186A Mutant as a Probe of the Hydrogen-Bond Network in the Chromophore Pocket and the Mechanism of Counterion Switch, J. Phys. Chem. C, 111, 8843-8848 (2007). Eefei Chen, Vanessa Van Vranken and David S. Kliger, The folding kinetics of the SDS-induced molten globule form of reduced cytochrome c, Biochemistry, 47, 5450-5459 (2008). Raymond M. Esquerra, Russell A. Jensen, Shyam Bhaskaran, Marlisa L. Pillsbury, Juan L. Mendoza, Benjamin W. Lintner, David S. Kliger and Robert A. Goldbeck, The pH Dependence of Heme Pocket Hydration and Ligand Rebinding Kinetics in Photodissociated Carbonmonoxymyoglobin, J. Biol. Chem, 283, 14165-14175 (2008). Terrie M. Williams, Mary Zavanelli, Melissa A. Miller, Robert A. Goldbeck, Michael Morledge, Dave Casper, D. Ann Pabst, William McLellan, Lucas P. Cantin and David S. Kliger, Running, swimming and diving modifies neuroprotecting globins in the mammalian brain, Proc. R. Soc. B, 275, 751-758 (2008). HOLMAN, THEODORE R. (b.1963) Professor. B.A, 1986, University of California, San Diego; Ph.D, 1991, University of Minneapolis, Minneapolis. Helen Hay Whitney Foundation Postdoctoral Fellowship, 1992, Harvard Medical School; Postdoctoral Fellowship, 1994, University of California, San Francisco. Biochemistry; Bioinorganic Chemistry. Use of biochemistry and inorganic chemistry to probe the biological function of metalloproteins from a rigorous chemical perspective. Current areas are structure/function and inhibitor studies of soybean and human lipoxygenases. TEL: (831) 459-5884 FAX: (831) 459-2935 Web: www.chemistry.ucsc.edu/faculty/holman.html Email: tholman@chemistry.ucsc.edu Alisha M. Thompson, Amit R. Reddi, Xiaoli Shi, Robert A. Goldbeck, Pierre Moeenne-Loccoz, Brian R. Gibney and Theodore R. Holman, Measurement of the Heme Affinity for Yeast Dap1p, and Its Importance in Cellular Function, Biochemistry, 46, 14629-14637 (2007). Joshua D. Deschamps, Jeffrey T. Gautschi, Stephanie Whitman, Tyler A. Johnson, Nadine C. Gassner, Phillip Crews and Theodore R. Holman, Discovery of platelet-type 12-human lipoxygenase selective inhibitors by high-throughput screening of structurally diverse libraries, Bioorg. Med. Chem, 15, 6900-6908 (2007). Yesseny Vasquez-Martinez, Rachana V. Ohri, Victor Kenyon, Theodore R. Holman and Silvia Sepulveda-Boza, Structure-activity relationship studies of flavonoids as potent inhibitors of human platelet 12-hLO, reticulocyte 15-hLO-1, and prostate epithelial 15-hLO-2, Bioorg. Med. Chem, 15, 7408-7425 (2007). Michael L. Neidig, Aaron T. Wecksler, Gerhard Schenk, Theodore R. Holman and Edward I. Solomon, Kinetic and Spectroscopic Studies of N694C Lipoxygenase: A Probe of the Substrate Activation Mechanism of a Nonheme Ferric Enzyme, J. Am. Chem. Soc, 129, 7531-7537 (2007). Claudia M. Boot, Nadine C. Gassner, Jennifer E. Compton, Karen Tenney, Craig M. Tamble, R. Scott Lokey, Theodore R. Holman and Phillip Crews, Pinpointing pseurotins from a marine-derived Aspergillus as tools for chemical genetics using a synthetic lethality yeast screen, J. Nat. Prod, 70, 16721675 (2007). Nadine C. Gassner, Craig M. Tamble, Jonathan E. Bock, Naomi Cotton, Kimberly N. White, Karen Tenney, Robert P. St. Onge, Michael J. Proctor, Guri Giaever, Ronald W. Davis, Phillip Crews, Theodore R. Holman and R. Scott Lokey, Accelerating the Discovery of Biologically Active Small Molecules Using a High-Throughput Yeast Halo Assay, J. Nat. Prod, 70, 383-390 (2007). Paul Ralifo, Laura Sanchez, Nadine C. Gassner, Karen Tenney, R. Scott Lokey, Theodore R. Holman, Frederick A. Valeriote and Phillip Crews, Pyrroloacridine Alkaloids from Plakortis quasiamphiaster: Structures and Bioactivity, J. Nat. Prod, 70, 95-99 (2007). Cyril Jacquot, Aaron T. Wecksler, Chris M. McGinley, Erika N. Segraves, Theodore R. Holman and Wilfred A. van der Donk, Isotope Sensitive Branching and Kinetic Isotope Effects in the Reaction of Deuterated Arachidonic Acids with Human 12- and 15-Lipoxygenases, Biochemistry, 47, 72957303 (2008). Aaron T. Wecksler, Victor Kenyon, Joshua D. Deschamps Alisha M. Thompson, Biochemical characterization of the heme binding protein dap1p. (D) KLIGER, DAVID S. (b.1943) Professor. B.S, 1965, Rutgers University; Ph.D, 1970, Cornell University. Postdoctoral Fellowship, 1970-1971, Harvard University. Biophysics/Biophysical Chemistry; Photochemistry. Time-resolved spectroscopic studies of transient species; photochemistry; biophysics; studies of the mechanism of visual transduction and heme protein functions; protein and peptide folding. TEL: (831) 459-2106 FAX: (831) 459-2760 Web: www.chemistry.ucsc.edu/faculty/kliger.html Email: kliger@chemistry.ucsc.edu Jacqueline Epps, Effects pf different environments on rhodopsin photochemistry. (D) KONOPELSKI, JOSEPH P. (b.1951) Professor. B.A, 1973, The Johns Hopkins University; M.A, 1973, The Johns Hopkins University; Ph.D, 1980, Stanford University. Postdoctoral Fellowship, 1981, Universite Louis Pasteur, Strasbourg, France; U.S.-France Exchange of Scientist Fellow, 1982, Universite Louis Pasteur, Strasbourg, France; Postdoctoral Fellowship, 19831984, University of Pennsylvania. Organic Chemistry; Synthesis. Natural products synthesis and synthetic methodology; asymmetric synthesis; heterocyclic chemistry; bioorganic chemistry. TEL: (831) 459-4676 FAX: (831) 459-2935 Web: www.chemistry.ucsc.edu/faculty/konopelski.html Email: joek@chemistry.ucsc.edu Kimberly N. White, Indranil Sen, Istvan Szundi, Yakira R. Landaverry, Lauren E. Bria, Joseph P. Konopelski, Marilyn M. Olmstead and Oloef Einarsdottir, Synthesis and structural characterization of cross-linked histidine-phenol Cu(II) complexes as cytochrome c oxidase active site models, Chem. Commun. (Cambridge, U. K.), 3252-3254 (2007). Jibo Xia, Lauren E. Brown and Joseph P. Konopelski, Welwistatin Support Studies: Expansion and Limitation of Aryllead(IV) Coupling Reactions, J. Org. Chem, 72, 68856890 (2007). Wei Chen, Shaowei Chen, Feizhi Ding, Haobin Wang, Lauren E. Brown and Joseph P. Konopelski, NanoparticleMediated Intervalence Transfer, J. Am. Chem. Soc, 130, 12156-12162 (2008). 4 CALIFORNIA, SANTA CRUZ Brian S. Gerstenberger, Jinzhen Lin, Yvette S. Mimieux, Lauren E. Brown, Allen G. Oliver and Joseph P. Konopelski, Structural Characterization of an Enantiomerically Pure Amino Acid Imidazolide and Direct Formation of the -Lactam Nucleus from an ␣-Amino Acid, Org. Lett, 10, 369-372 (2008). Jinzhen Lin, Brian S. Gerstenberger, Nhu Y. T. Stessman and Joseph P. Konopelski, Diazonamide Support Studies: Stereoselective Formation of the C10 Chiral Center in both the CDEFG and AEFG Fragments, Org. Lett, 10, 3969-3972 (2008). Brian S. Gerstenberger, Progress towards the total synthesis of diazonamide a and related new methodology. (D) Jibo Xia, Progress toward the total synthesis of N-methylwelwitindolinone C isothiocyanate: Expansion and limitation of aryllead(IV) coupling reactions. (D) Yakira R. Landaverry, Histidine-tyrosine side chain bonding: 1) Synthesis of cytochrome C oxidase active site model systems. 2) Synthetic methodology for the synthesis of the core histidine-tyrosine dipeptide assembly of the natural products aciculitins A-C, progress towa. (D) LI, YAT (b.1977) Assistant Professor. B.Sc, 1999, The University of Hong Kong; Ph.D, 2002, The University of Hong Kong. Postdoctoral Fellow, 2003-2007, Harvard University. Nanochemistry; Solid State Chemistry. Semiconductor nanowires and nanowire heterostructures; Metal-Organic Chemical Vapor Deposition (MOCVD) and Chemical Vapor Deposition (CVD); nanophotonics: nanowire-based multicolor light emitting and laser diodes; nanoelectronics: nanoscale field-effect transistors and high electron mobility transistors. TEL: (831) 4591952 FAX: (831) 459-2935 Web: chemistry.ucsc.edu/faculty/Li Email: yli@chemistry.ucsc.edu Andrew B. Greytak, Carl J. Barrelet, Yat Li and Charles M. Lieber, Semiconductor nanowire laser and nanowire waveguide electro-optic modulators, Appl. Phys. Lett, 87, 151103 (2005). Silvija Gradecak, Fang Qian, Yat Li, Hong-Gyu Park and Charles M. Lieber, GaN nanowire lasers with low lasing thresholds, Appl. Phys. Lett, 87, 173111 (2005). Fang Qian, Silvija Gradecak, Yat Li, Cheng-Yen Wen and Charles M. Lieber, Core/multishell nanowire heterostructures as multicolor, high-efficiency light-emitting diodes, Nano Lett, 5, 2287-2291 (2005). Yat Li, Fang Qian, Jie Xiang and Charles M. Lieber, Electronic and optoelectronic properties of nanowires, Material Today, 9, 18-27 (2006). Yat Li, Jie Xiang, Fang Qian, Silvija Gradecak, Yue Wu, Hao Yan, Douglas A. Blom and Charles M. Lieber, Dopantfree GaN/AlN/AlGaN radial nanowire heterostructures as high electron mobility transistors, Nano Lett, 6, 1468-1471 (2006). Hong-Gyu Park, Fang Qian, Carl J. Barrelet and Yat Li, Microstadium single-nanowire laser, Appl. Phys. Lett, 91, 251115/1-251115/3 (2007). Xiaocheng Jiang, Qihua Xiong, Sungwoo Nam, Fang Qian, Yat Li and Charles M. Lieber, InAs/InP Radial Nanowire Heterostructures as High Electron Mobility Devices, Nano Lett, 7, 3214-3218 (2007). Fang Qian, Yat Li, Silvija Gradecak, Hong-Gyu Park, Yajie Dong, Yong Ding, Zhong Lin Wang and Charles M. Lieber, Multi-quantum-well nanowire heterostructures for wavelength-controlled lasers, Nat. Mater, 7, 701-706 (2008). LININGTON, ROGER G. (b.1975) Assistant Professor. B.Sc, 1998, University of Leeds, UK; Ph.D, 2004, University of British Columbia, Canada. Postdoctoral Researcher, 2005-2007, Scripps Institution of Oceanography. Chemical Biology; Organic Chemistry. Marine natural products, drugs for neglected diseases, chemical biology, chemical probes. TEL: (831) 459-3014 FAX: (831) 459-2935 Web: chemistry.ucsc.edu/faculty/linington.html Email: rogerl@chemistry.ucsc.edu Roger G. Linington, Jose Gonzalez, Luis-David Urena, Luz I. Romero, Eduardo Ortega-Barria and William H. Gerwick, Venturamides A and B: Antimalarial Constituents of the Panamanian Marine Cyanobacterium Oscillatoria sp, J. Nat. Prod, 70, 397-401 (2007). Kerry L. McPhail, Jhonny Correa, Roger G. Linington, Jose Gonzalez, Eduardo Ortega-Barria, Todd L. Capson and William H. Gerwick, Antimalarial Linear Lipopeptides from a Panamanian Strain of the Marine Cyanobacterium Lyngbya majuscula, J. Nat. Prod, 70, 984-988 (2007). Roger G. Linington, Daniel J. Edwards, Cynthia F. Shuman, Kerry L. McPhail, Teatulohi Matainaho and William H. Gerwick, Symplocamide A, a Potent Cytotoxin and Chymotrypsin Inhibitor from the Marine Cyanobacterium Symploca sp, J. Nat. Prod, 71, 22-27 (2008). LOKEY, R. SCOTT (b.1967) Associate Professor. B.S, 1989, Trinity University; Ph.D, 1997, University of Texas, Austin. Post-doctoral fellow, 1997-1998, Genentech, Inc; Post-doctoral fellow, 1998-2001, Harvard Medical School. Bioorganic Chemistry; Chemical Biology. Actin cell biology. Diversity-oriented synthesis of cyclic peptide libraries for phenotype-based screening. Chemical genetics. TEL: (831) 459-1307 FAX: (831) 459-2935 Web: www.chemistry.ucsc.edu/faculty/lokey.html Email: lokey@chemistry.ucsc.edu Laura A. Schuresko and R. Scott Lokey, A practical solidphase synthesis of Glu7-phalloidin and entry into fluorescent F-actin-binding reagents, Angew. Chem., Int. Ed, 46, 35473549 (2007). Michael T. Nehil, Craig M. Tamble, David J. Combs, Douglas R. Kellogg and R. Scott Lokey, Uncovering genetic relationships using small molecules that selectively target yeast cell cycle mutants, Chem. Biol. Drug Des, 69, 258-264 (2007). Claudia M. Boot, Nadine C. Gassner, Jennifer E. Compton, Karen Tenney, Craig M. Tamble, R. Scott Lokey, Theodore R. Holman and Phillip Crews, Pinpointing pseurotins from a marine-derived Aspergillus as tools for chemical genetics using a synthetic lethality yeast screen, J. Nat. Prod, 70, 16721675 (2007). Nadine C. Gassner, Craig M. Tamble, Jonathan E. Bock, Naomi Cotton, Kimberly N. White, Karen Tenney, Robert P. St. Onge, Michael J. Proctor, Guri Giaever, Ronald W. Davis, Phillip Crews, Theodore R. Holman and R. Scott Lokey, Accelerating the Discovery of Biologically Active Small Molecules Using a High-Throughput Yeast Halo Assay, J. Nat. Prod, 70, 383-390 (2007). Paul Ralifo, Laura Sanchez, Nadine C. Gassner, Karen Tenney, R. Scott Lokey, Theodore R. Holman, Frederick A. Valeriote and Phillip Crews, Pyrroloacridine Alkaloids from Plakortis quasiamphiaster: Structures and Bioactivity, J. Nat. Prod, 70, 95-99 (2007). Rushia A. Turner, Allen G. Oliver and R. Scott Lokey, Click Chemistry as a Macrocyclization Tool in the SolidPhase Synthesis of Small Cyclic Peptides, Org. Lett, 9, 50115014 (2007). David J. Combs and R. Scott Lokey, Extended peptoids: a new class of oligomers based on aromatic building blocks, Tetrahedron Lett, 48, 2679-2682 (2007). Laura Schuresko, From toadstool to test tube: A phallotoxin tale. (D) Taha Rezai, The passive membrane permeability of cyclic peptides. (D) MASCHARAK, PRADIP K. (b.1953) Professor. B.Sc.(Hons.in Chem), 1971, University of Burdwan, India; M.S. (Inorg.Chem.Special), 1973, University of Burdwan, India; Ph.D, 1979, Indian Institute of Technology, Kanpur, India. Postdoctoral Fellowship, 1980, Stanford University; Postdoctoral Fellowship, 1981-1982, Harvard University; Bristol-Myers Research Associate, 1983-1984, Massachusetts Institute of Technology (MIT). Bioinorganic Chemistry; Medicinal and/or Pharmaceutical Chemistry. Synthetic analogue approach to active sites of metalloenzymes; studies on drug-receptor interactions at a molecular level; alkane oxidation by designed metal complexes as catalysts; synthesis of designed NO-donors for photodynamic therapy. TEL: (408) 459-4251 FAX: (408) 459-2935 Web: www.chemistry.ucsc.edu/faculty/mascharak.html Email: pradip@chemistry.ucsc.edu Aura A. Eroy-Reveles, C. Gianna Hoffman-Luca and Pradip K. Mascharak, Formation of a triply bridged -oxo diiron (iii) core stabilized by two deprotonated carboxamide groups upon photorelease of NO from a {Fe-NO}6 iron nitrosyl, Dalton Trans, 5268-5274 (2007). Michael J. Rose, Apurba K. Patra, Eric A. Alcid, Marylin M. Olmstead and Pradip K. Mascharak, Ruthenium Nitrosyls Derived from Polypyridine Ligands with Carboxamide or Imine Nitrogen Donor(s): Isoelectronic Complexes with Different NO Photo-lability, Inorg. Chem. (Washington, DC, U. S.), 46, 2328-2338 (2007). Genevieve M. Halpenny, Marilyn M. Olmstead and Pradip K. Mascharak, Incorporation of a Designed Ruthenium Nitrosyl in PolyHEMA Hydrogel and Light-Activated Delivery of NO to Myoglobin, Inorg. Chem. (Washington, DC, U. S.), 46, 6601-6606 (2007). Michael J. Rose, Marilyn M. Olmstead and Pradip K. Mascharak, Photosensitization via Dye Coordination: A New Strategy to Synthesize Metal Nitrosyls That Release NO under Visible Light, J. Am. Chem. Soc, 129, 5342-5343 (2007). Michael J. Rose, Marilyn M. Olmstead and Pradip K. Mascharak, Photoactive ruthenium nitrosyls derived from quinoline- and pyridine-based ligands: Accelerated photorelease of NO due to quinoline ligation, Polyhedron, 26, 4713-4718 (2007). Michael J. Rose and Pradip K. Mascharak, A photosensitive {Ru-NO}6 nitrosyl bearing dansyl chromophore: novel NO donor with a fluorometric on/off switch, Chem. Commun. (Cambridge, U. K.), 3933-3935 (2008). Michael J. Rose and Pradip K. Mascharak, Photoactive ruthenium nitrosyls: Effects of light and potential application as NO donors, Coord. Chem. Rev, 252, 2093-2114 (2008). Michael J. Rose and Pradip K. Mascharak, Fiat Lux: selective delivery of high flux of nitric oxide (NO) to biological targets using photoactive metal nitrosyls, Curr. Opin. Chem. Biol, 12, 238-244 (2008). Aura A. Eroy-Reveles, Yvonne Leung, Christine M. Bea- vers, Marilyn M. Olmstead and Pradip K. Mascharak, NearInfrared Light Activated Release of Nitric Oxide from Designed Photoactive Manganese Nitrosyls: Strategy, Design, and Potential as NO Donors, J. Am. Chem. Soc, 130, 44474458 (2008). Michael J. Rose, Nicole L. Fry, Rebecca Marlow, Lindsay Hinck and Pradip K. Mascharak, Sensitization of Ruthenium Nitrosyls to Visible Light via Direct Coordination of the Dye Resorufin: Trackable NO Donors for Light-Triggered NO Delivery to Cellular Targets, J. Am. Chem. Soc, 130, 88348846 (2008). Aura Alegra Eroy-Reveles, Synthesis of photoactive manganese nitrosyl compounds and materials for the light controlled release of nitric oxide. (D) MILLHAUSER, GLENN L. (b.1956) Professor. B.S, 1980, California State University Los Angeles; Ph.D, 1986, Cornell University. NIH Fellowship, 1988, Cornell University. Biophysics/Biophysical Chemistry; Neuroscience. Biophysical chemistry, prions, agouti-related protein, melanocortin receptors, electron spin resonance; time-domain ESR; nuclear magnetic resonance. TEL: (831) 459-2176 FAX: (831) 459-2935 Web: www.chemistry.ucsc.edu/faculty/millhauser.html Email: glennm@chemistry.ucsc.edu P. McCarthy, M. Chattopadhyay, G. L. Millhauser, N. V. Tsarevsky, L. Bombalski, K. Matyjaszewski, D. Shimmin, N. Avdalovic and C. Pohl, Nanoengineered analytical immobilized metal affinity chromatography stationary phase by atom transfer radical polymerization: Separation of synthetic prion peptides, Anal. Biochem, 366, 1-8 (2007). Glenn L. Millhauser, Copper and the prion protein: methods, structures, function, and disease, Annu. Rev. Phys. Chem, 58, 299-320 (2007). Leo Seballos, Nicole Richards, Daniel J. Stevens, Mira Patel, Laura Kapitzky, Scott Lokey, Glenn Millhauser and Jin Z. Zhang, Competitive binding effects on surface-enhanced Raman scattering of peptide molecules, Chem. Phys. Lett, 447, 335-339 (2007). Bin Yu and Glenn L. Millhauser, Chemical disulfide mapping identifies an inhibitor cystine knot in the agouti signaling protein, FEBS Lett, 581, 5561-5565 (2007). Eric D. Walter, Daniel J. Stevens, Micah P. Visconte and Glenn L. Millhauser, The Prion Protein is a Combined Zinc and Copper Binding Protein: Zn2+ Alters the Distribution of Cu2+ Coordination Modes, J. Am. Chem. Soc, 129, 1544015441 (2007). Jijun Dong, Jesse D. Bloom, Vladimir Goncharov, Madhuri Chattopadhyay, Glenn L. Millhauser, David G. Lynn, Thomas Scheibel and Susan Lindquist, Probing the Role of PrP Repeats in Conformational Conversion and Amyloid Assembly of Chimeric Yeast Prions, J. Biol. Chem, 282, 3420434212 (2007). Sophie I. Candille, Christopher B. Kaelin, Bruce M. Cattanach, Bin Yu, Darren A. Thompson, Matthew A. Nix, Julie A. Kerns, Sheila M. Schmutz, Glenn L. Millhauser, Gregory S. Barsh, C. C. Little and J. A. Kerns, A -Defensin Mutation Causes Black Coat Color in Domestic Dogs, Science (Washington, DC, U. S.), 318, 1418-1423 (2007). C. B. Kaelin, S. I. Candille, B. Yu, P. Jackson, D. A. Thompson, M. A. Nix, J. Binkley, G. L. Millhauser and G. S. Barsh, New ligands for melanocortin receptors, Int. J. Obes, 32, S19-S27 (2008). Jean Ruehl, Nicole L. Hill, Eric D. Walter, Glenn L. Millhauser and Rebecca Braslau, A proximal bisnitroxide initiator: Studies in low-temperature nitroxide-mediated polymerizations, Macromolecules, 41, 1972-1982 (2008). Bin Yu, Scaffold study of ASIP and AgRP: Antagonists of melanocortin system. (D) Daniel J. Stevens, Metal binding behavior of the prion protein and relevance to disease progression. (D) OLIVER, SCOTT R. J. (b.1969) Associate Professor. B.Sc, 1992, University of Toronto; Ph.D, 1997, University of Toronto. NSERC Postdoctoral Fellowship, 19971999, Harvard University. Materials Chemistry; Materials Science. Nanoporous materials for catalysis; polymer templation for dye-sensitized solar cells. TEL: (831) 459-5448 FAX: (831) 459-2935 Web: www.chemistry.ucsc.edu/faculty/oliver.html Email: soliver@chemistry.ucsc.edu Xiaojuan Fan, David L. Rogow, Claudia H. Swanson, Akhilesh Tripathi and Scott R. J. Oliver, Contact printed Co/insulator/Co molecular junctions, Appl. Phys. Lett, 90, 163114/ 1-163114/3 (2007). David L. Rogow, Gustavo Zapeda, Claudia H. Swanson, Xiaojuan Fan, Charles F. Campana, Allen G. Oliver and Scott R. J. Oliver, A Metal-Organic Framework Containing Cationic Inorganic Layers: Pb2F2[C2H4(SO3)2], Chem. Mater, 19, 4658-4662 (2007). Onyango M. Tedmann, Stanley K. Madan, Peter Y. Zavalij and Scott R. J. Oliver, Crystal structure and fluorescence of a europium(III) complex: EuCl3(2,2’-bipyridine-N,N’-dioxide) ·2CH3OH, Inorg. Chim. Acta, 360, 3408-3413 (2007). Xiaojuan Fan, David P. Demaree, Jessica M. St. John, Akhilesh Tripathi and Scott R. J. Oliver, Double-layer porous CALIFORNIA, SANTA CRUZ TiO2 electrodes for solid-state dye-sensitized solar cells, Appl. Phys. Lett, 92, 193108/1-193108/3 (2008). Claudia H. Swanson, Harris A. Shaikh, David L. Rogow, Allen G. Oliver, Charles F. Campana and Scott R. J. Oliver, Antimony Oxide Hydroxide Ethanedisulfonate: a Cationic Layered Metal Oxide for Lewis Acid Applications, J. Am. Chem. Soc, 130, 11737-11741 (2008). RUBIN, SETH M. (b.1976) Assistant Professor. B.A, 1998, Columbia University; Ph.D, 2003, University of California, Berkeley. Postdoctoral Fellow, 2003-2006, Memorial Sloan-Kettering Cancer Center. Biochemistry; Structural Biology. Biochemistry and biophysical chemistry; molecular mechanisms of cell cycle regulation, nuclear magnetic resonance, x-ray crystallography. TEL: (831) 459-1921 FAX: (831) 459-2935 Web: www.chemistry.ucsc.edu/faculty/srubin.html Email: srubin@ucsc.edu No publication information submitted for this edition. SCHLEICH, THOMAS W. (b.1938) Professor. B.S, 1960, Cornell University; Ph.D, 1966, Rockefeller University. Resident Associate, 1967, Dartmouth College; Resident Associate, 1968; Helen Hay Whitney Foundation Fellowship, 1969, University of Oregon. Biophysics/ Biophysical Chemistry; NMR Spectroscopy. In vivo magnetic resonance spectroscopy; magnetic resonance imaging; development of NMR techniques for metabolite spectral editing and quantitation; development of NMR techniques for metabolite rotational diffusion in vivo. Application of MRS and MRI to human muscle pathophysiology. TEL: (831) 459-2067 FAX: (831) 459-2935 Web: www.chemistry.ucsc.edu/faculty/schleich.html Email: schleich@chemistry.ucsc.edu No publication information submitted for this edition. SCOTT, WILLIAM G. (b.1963) Associate Professor. B.S, 1985, Bates College; Ph.D, 1992, University of California, Berkeley. American Cancer Society Fellowship, 1993-1996, M. R. C. Laboratory of Molecular Biology, Cambridge, UK. Crystallography; Structural Biology. Structural basis of ribozyme catalysis and the origin of life. TEL: (831) 459-5367 FAX: (831) 459-2935 Web: www.chemistry.ucsc.edu/faculty/scott.html Email: wgscott@chemistry.ucsc.edu William G. Scott, Morphing the minimal and full-length hammerhead ribozymes: implications for the cleavage mechanism, Biol. Chem, 388, 727-735 (2007). William G. Scott, Ribozymes, Curr. Opin. Struct. Biol, 17, 280-286 (2007). Tai-Sung Lee, Carlos Silva-Lopez, Monika Martick, William G. Scott and Darrin M. York, Insight into the Role of Mg2+ in Hammerhead Ribozyme Catalysis from X-ray Crystallography and Molecular Dynamics Simulation, J. Chem. Theory Comput, 3, 325-327 (2007). Michael P. Robertson and William G. Scott, The structural basis of ribozyme-catalyzed RNA assembly, Science (Washington, DC, U. S.), 315, 1549-1553 (2007). Michael P. Robertson and William G. Scott, A general method for phasing novel complex RNA crystal structures without heavy-atom derivatives, Acta Crystallogr., Sect. D: Biol. Crystallogr, D64, 738-744 (2008). Tai-Sung Lee, Carlos Silva Lopez, George M. Giambasu, Monika Martick, William G. Scott and Darrin M. York, Role of Mg2+ in hammerhead ribozyme catalysis from molecular simulation, J. Am. Chem. Soc, 130, 3053-3064 (2008). Monika Martick, Lucas H. Horan, Harry F. Noller and William G. Scott, A discontinuous hammerhead ribozyme embedded in a mammalian messenger RNA, Nature (London, U. K.), 454, 899-902 (2008). Young-In Chi, Monika Martick, Monica Lares, Rosalind Kim, William G. Scott and Sung-Hou Kim, Capturing hammerhead ribozyme structures in action by modulating general base catalysis, PLoS Biol, 6, 2060-2068 (2008). William G. Scott, Hammerhead ribozyme crystal structures and catalysis, Ribozymes RNA Catal, 48-65 (2008). Daniel J. Koslover, Anastasia J. Callaghan, Maria J. Marcaida, Elspeth F. Garman, Monika Martick, William G. Scott and Ben F. Luisi, The Crystal Structure of the Escherichia coli RNase E Apoprotein and a Mechanism for RNA Degradation, Structure (Cambridge, MA, U. S.), 16, 1238-1244 (2008). SINGARAM, BAKTHAN (b.1950) Professor. B.Sc, 1969, University of Madras, India; M.Sc, 1971, University of Madras; Ph.D, 1977, University of Madras. Postdoctoral Fellowship, 1977-1980, Purdue University; Postdoctoral Fellowship, 1980-1982, University College, Swansea, U. K; Associate Research Scientist, 19821989, Purdue University. Organic Chemistry. Exploratory synthetic organic chemistry; asymmetric synthesis; development of synthetic methods and organometallic reagents for the synthesis of optically active organic compounds of biological and medicinal significance; utilization of modified hydrides. TEL: (831) 459-3154 FAX: (831) 459-2935 Web: www.chemistry.ucsc.edu/faculty/singaram.html Email: singaram@chemistry.ucsc.edu David B. Cordes, Aaron Miller, Soya Gamsey and Bakthan Singaram, Simultaneous use of multiple fluorescent reporter dyes for glucose sensing in aqueous solution, Anal. Bioanal. Chem, 387, 2767-2773 (2007). Soya Gamsey, Aaron Miller, Marilyn M. Olmstead, Christine M. Beavers, Lacie C. Hirayama, Sulolit Pradhan, Ritchie A. Wessling and Bakthan Singaram, Boronic Acid-Based Bipyridinium Salts as Tunable Receptors for Monosaccharides and ␣-Hydroxycarboxylates, J. Am. Chem. Soc, 129, 12781286 (2007). Lubov Pasumansky, Christopher J. Collins, Lawrence M. Pratt, Ngan Van Nguyen, B. Ramachandran and Bakthan Singaram, Solvent and Temperature Effects on the Reduction and Amination Reactions of Electrophiles by Lithium Dialkylaminoborohydrides, J. Org. Chem, 72, 971-976 (2007). Christian T. Goralski, Dennis L. Hasha, Bakthan Singaram and Derek Steiner, Scale-Up of the Preparation of (1R,2R,4S)-1-Methyl-4-(1-methylethenyl)-2-(4-morpholinyl) cyclohexanol, Org. Process Res. Dev, 11, 776-779 (2007). Zachary Sharrett, Soya Gamsey, Jonathan Fat, Daniel Cunningham-Bryant, Ritchie A. Wessling and Bakthan Singaram, The effect of boronic acid acidity on performance of viologen-based boronic acids in a two-component optical glucose-sensing system, Tetrahedron Lett, 48, 5125-5129 (2007). Scott Eagon, Jinsoo Kim, Katie Yan, Dustin Haddenham and Bakthan Singaram, Asymmetric reductions using the chiral boronic ester TarB-H: a practical and inexpensive procedure for synthesizing chiral alcohols, Tetrahedron Lett, 48, 9025-9029 (2007). Alexander Schiller, Boaz Vilozny, Ritchie A. Wessling and Bakthan Singaram, Recognition of phospho sugars and nucleotides with an array of boronic acid appended bipyridinium salts, Anal. Chim. Acta, 627, 203-211 (2008). Lubov Pasumansky, Dustin Haddenham, Jacob W. Clary, Gary B. Fisher, Christian T. Goralski and Bakthan Singaram, Lithium aminoborohydrides 16. Synthesis and Reactions of Monomeric and Dimeric Aminoboranes, J. Org. Chem, 73, 1898-1905 (2008). Caitlin M. Binder, Darryl D. Dixon, Erik Almaraz, Marcus A. Tius and Bakthan Singaram, A simple procedure for C-C bond cleavage of aromatic and aliphatic epoxides with aqueous sodium periodate under ambient conditions, Tetrahedron Lett, 49, 2764-2767 (2008). Zachary Sharrett, Soya Gamsey, Paul Levine, Dan Cunningham-Bryant, Boaz Vilozny, Alexander Schiller, Ritchie A. Wessling and Bakthan Singaram, Boronic acid-appended bis-viologens as a new family of viologen quenchers for glucose sensing, Tetrahedron Lett, 49, 300-304 (2008). Terra D. Haddad, Lacie C. Hirayama, Philip Taynton and Bakthan Singaram, Asymmetric indium-mediated Barbiertype allylation reactions with ketones to form homoallylic alcohol products, Tetrahedron Lett, 49, 508-511 (2008). Lacie Hirayama, Novel reactions of organoindium compounds: The synthesis of chiral alcohols, allylboron reagents and identification of the reactive intermediates. (D) Zachary Sharrett, Design and synthesis of substituted boronic acid containing mono-viologen and bis-viologen quenchers: Optimization of the two-component saccharide sensing system. (D) SMITH, DONALD R. (b.1957) Professor. B.A, 1980, University of California, Santa Cruz; M.A, 1985, San Francisco State University; Ph.D, 1991, University of California, Santa Cruz. Postdoctoral Fellow in Toxicology, 1992-1993, University of Maryland Medical School. Neuroscience; Toxicology. Fundamental mechanisms underlying the responses and adaptations of organisms to toxic exposures; efficacy of clinical treatments for metal toxicity; toxicology and metabolism of metals. TEL: (831) 459-5041 FAX: (831) 459-3524 Web: natsci.ucsc.edu/acad/etox/faculty.html Email: smith@etox.ucsc.edu Diane E. Stangle, Donald R. Smith, Stephane A. Beaudin, Myla S. Strawderman, David A. Levitsky and Barbara J. Strupp, Succimer chelation improves learning, attention, and arousal regulation in lead-exposed rats but produces lasting cognitive impairment in the absence of lead exposure, Environ. Health Perspect, 115, 201-209 (2007). Myra E. Finkelstein, Keith A. Grasman, Donald A. Croll, Bernie R. Tershy, Bradford S. Keitt, Walter M. Jarman and Donald R. Smith, Contaminant-associated alteration of immune function in black-footed albatross (Phoebastria nigripes ), a North Pacific predator, Environ. Toxicol. Chem, 26, 1896-1903 (2007). Daniel R. Crooks, Manik C. Ghosh, Michelle Braun-Sommargren, Tracey A. Rouault and Donald R. Smith, Manganese targets m-aconitase and activates iron regulatory protein 2 in AF5 GABAergic cells, J. Neurosci. Res, 85, 1797-1809 (2007). Stephane A. Beaudin, Diane E. Stangle, Donald R. Smith, David A. Levitsky and Barbara J. Strupp, Succimer chelation normalizes reactivity to reward omission and errors in leadexposed rats, Neurotoxicol. Teratol, 29, 188-202 (2007). Daniel R. Crooks, Nicholas Welch and Donald R. Smith, Low-level manganese exposure alters glutamate metabolism in GABAergic AF5 cells, NeuroToxicology, 28, 548-554 (2007). 5 Molly E. Church, Roberto Gwiazda, Donald R. Smith, Robert W. Risebrough, Kelly Sorenson, C. Page Chamberlain, Sean Farry, William Heinrich and Bruce A. Rideout, Response to Comment on “Ammunition is the Principal Source of Lead Accumulated by California Condors Re-Introduced to the Wild, Environ. Sci. Technol, 42, 1809-1811 (2008). STONE, MICHAEL D. (b.1975) Assistant Professor. B.A, 1997, University of Pennsylvania; Ph.D, 2003, University of California, Berkeley. Postdoctoral Fellowship, 2004-2007, Harvard University. Biochemistry; Biophysics/Biophysical Chemistry. Single-molecule biophysics and enzymology; dynamics of protein-nucleic acid interactions and mechanism of biological motors; structure, function, and assembly of the telomerase ribonucleoprotein, Fluorescence Resonance Energy Transfer (FRET), optical/magnetic trapping, sub-diffraction optical imaging of telomeres and the nucleus. TEL: (831) 459-2845 FAX: (831) 459-2935 Web: chemistry.ucsc.edu/faculty/Stone.html Email: mstone@chemistry.ucsc.edu J. Gore, Z. Bryant, M. D. Stone, M. Nollmann, N. R. Cozzarelli and C. Bustamante, Mechanochemical analysis of DNA gyrase using rotor bead tracking, Nature, 439, 100-104 (2006). Marcelo Noellmann, Michael D. Stone, Zev Bryant, Jeff Gore, Nancy J. Crisona, Seok-Cheol Hong, Sylvain Mitelheiser, Anthony Maxwell, Carlos Bustamante and Nicholas R. Cozzarelli, Multiple modes of Escherichia coli DNA gyrase activity revealed by force and torque, Nat. Struct. Mol. Biol, 14, 264-271 (2007). Michael D. Stone, Mariana Mihalusova, Catherine M. O’Connor, Ramadevi Prathapam, Kathleen Collins and Xiaowei Zhuang, Stepwise protein-mediated RNA folding directs assembly of telomerase ribonucleoprotein, Nature (London, U. K.), 446, 458-461 (2007). SWITKES, EUGENE (b.1943) Professor. A.B, 1965, Oberlin College; M.A, 1970, Harvard University; Ph.D, 1970, Harvard University. NSF Postdoctoral Fellowship, 1970-1971, Cambridge University. Physical Chemistry; Theoretical Chemistry. Electronic structure of molecules; mechanism of visual accommodation; visual information processing; color vision; diabetes; evoked potentials. TEL: (831) 459-2000 FAX: (831) 459-2935 Web: www.chemistry.ucsc.edu/faculty/switkes.html Email: switkes@chemistry.ucsc.edu switkes@ucsc.edu E. Switkes, Contrast salience across three-dimensional chromoluminance space, Vision Research, 48, 1812-1819 (2008). WIPKE, W. TODD (b.1940) Professor. B.S, 1962, University of Missouri, Columbia; Ph.D, 1965, University of California, Berkeley. Postdoctoral Fellowship, 1967-1969, Harvard University; Assistant Professor, 1969-1975, Princeton University; Associate Professor, 1975-1981, University of California, Santa Cruz; Alexander von Humboldt Fellowship, 1987-1988, Technical University, Munich. Bioinformatics; Computational Chemistry. Computer-assisted design of combinatorial chemistry; computer design of drugs; molecular engineering; supramolecular chemistry; computer-assisted instruction. TEL: (831) 459-2397 FAX: (831) 459-2935 Web: www.chemistry.ucsc.edu/faculty/wipke.html Email: wipke@chemistry.ucsc.edu No publication information submitted for this edition. ZHANG, JIN Z. (b.1962) Professor. B.S, 1983, Fudan University, Shanghai, China; Ph.D, 1989, University of Washington, Seattle. Postdoctoral Fellow, 1989-1992, University of California, Berkeley. Materials Chemistry; Physical Chemistry. Design, synthesis, characterization and applications of semiconductor, metal and metal oxide nanomaterials; femtosecond laser spectroscopy and ultrafast dynamics at liquid-solid interfaces; sensing and detection of cancer biomarkers; surface-enhanced Raman scattering (SERS); charge and energy transfer on surface and at interfaces; solar energy conversion and hydrogen generation. TEL: (831) 459-3776 FAX: (831) 459-2935 Web: www.chemistry.ucsc.edu/faculty/zhang.html Email: zhang@chemistry.ucsc.edu Yi Zhang, C. Shi, C. Gu, L. Seballos and J. Z. Zhang, Liquid core photonic crystal fiber sensor based on surface enhanced raman scattering, Appl. Phys. Lett, 90, 193504193506 (2007). Yi Zhang, Chao Shi, Claire Gu, Leo Seballos and Jin Z. Zhang, Liquid core photonic crystal fiber sensor based on surface enhanced Raman scattering, Appl. Phys. Lett, 90, 193504/1-193504/3 (2007). Philip Measor, Leo Seballos, Dongliang Yin, Jin Z. Zhang, Evan J. Lunt, Aaron R. Hawkins and Holger Schmidt, Onchip surface-enhanced Raman scattering detection using integrated liquid-core waveguides, Appl. Phys. Lett, 90, 211107/ 1-211107/3 (2007). 6 CALIFORNIA, SANTA CRUZ S. M. Dybiec, A. Chornokur, S. Ostapenko, A. Wolcott, D. Ortiz, J. Z. Zhang, A. Zajac, C. Phelan and T. Sellers, Photoluminescence spectroscopy of bio-conjugated CdSe/ZnS quantum dots, Appl. Phys. Lett, 90, 263112 (2007). Nadejda Rozanova, Jin Z. Zhang and Diane E. Heck, Catalytic therapy of cancer with porphyrins and ascorbate, Cancer Lett. (Amsterdam, Neth.), 252, 216-224 (2007). Leo Seballos, Nicole Richards, Daniel J. Stevens, Mira Patel, Laura Kapitzky, Scott Lokey, Glenn Millhauser and Jin Z. Zhang, Competitive binding effects on surface-enhanced Raman scattering of peptide molecules, Chem. Phys. Lett, 447, 335-339 (2007). Nadejda Rozanova (Torshina), Jin Z. Zhang and Diane E. Heck, Catalytic therapy of cancer with ascorbate and extracts of medicinal herbs, Evidence-based Complementary and Alternative Medicine, 4, 1-10 (2007). Adam M. Schwartzberg, Tammy Y. Olson, Chad E. Talley and Jin Z. Zhang, Gold nanotubes synthesized via magnetic alignment of cobalt nanoparticles as templates, J. Phys. Chem. C, 111, 16080-16082 (2007). A. M. Schwartzberg, C. D. Grant, Tony van Buuren and J. Z. Zhang, Reduction of HAuCl4 by Na2S revisited: The case for Au nanoparticle aggregates and against Au2S/Au core/ shell particles, J. Phys. Chem. C, 111, 8892-8901 (2007). Fanxin Wu, Jung Ho Yu, Jin Joo, Taeghwan Hyeon and Jin Z. Zhang, Ultrafast electronic dynamics of monodisperse PbS and CdS nanoparticles/nanorods: Effects of size on nonlinear relaxation, Opt. Mater, 29, 858-866 (2007). Fanxin Wu, Jung Ho Yu, Jin Joo, Taeghwan Hyeon and Jin Z. Zhang, Ultrafast electronic dynamics of monodisperse PbS and CdS nanoparticles/nanorods: effects of size on nonlinear relaxation, Opt. Mater. (Amsterdam, Neth.), 29, 858-866 (2007). Zilu Wu, Anindya Ghosh-Roy, Mehmet Fatih Yanik, Jin Z. Zhang, Yishi Jin and Andrew D. Chisholm, Caenorhabditis elegans neuronal regeneration is influenced by life stage, ephrin signaling, and synaptic branching, Proc. Natl. Acad. Sci. U. S. A, 104, 15132-15137 (2007). Leo Seballos, Rebecca Newhouse, Jin Z. Zhang, Eric Majzoub and Ewa Roennebro, Temperature-dependent Raman scattering study of LiAlH4 and Li3AlH6, Proc. SPIE-Int. Soc. Opt. Eng, 6650, 66500N/1-66500N/6 (2007). Rebecca Newhouse, Leo Seballos, J. Z. Zhang, Eric Majzoub and Ewa Ronnebro, Temperature dependent Raman scattering study of LiAlH4 and Li3AlH6, SPIE Proc, 6650, 0N1-0N6 (2007). Y. Zhang, C. Shi, C. Gu, B. Chen, L. Seballos, A. M. Schwartzberg and J. Z. Zhang, Molecular probes based on microstructured fibers and surface enhanced raman scattering, SPIE Proc, 6698, 0U1-0U11 (2007). Kenneth L. Knappenberger, Jr., Daryl B. Wong, Wei Xu, Adam M. Schwartzberg, Abraham Wolcott, Jin Z. Zhang and Stephen R. Leone, Excitation-Wavelength Dependence of Fluorescence Intermittency in CdSe Nanorods, ACS Nano, 2, 2143-2153 (2008). J. Z. Zhang and C. D. Grant, Optical and dynamic properties of semiconductor nanomaterials, Ann. Rev. of Nano Research, 2, 1 (2008). Chao Shi, He Yan, Claire Gu, Debraj Ghosh, Leo Seballos, Shaowei Chen, Jin Z. Zhang and Bin Chen, A double substrate “sandwich” structure for fiber surface enhanced Raman scattering detection, Appl. Phys. Lett, 92, 103107/1-103107/3 (2008). Chao Shi, Chao Lu, Claire Gu, Lei Tian, Rebecca Newhouse, Shaowei Chen and Jin Z. Zhang, Inner wall coated hollow core waveguide sensor based on double substrate surface enhanced raman scattering, Appl. Phys. Lett, 93, 153101 (2008). Nadejda Rozanova and Jin Z. Zhang, Metal and magnetic nanostructures for cancer detection, imaging and therapy, J. Biomed. Nanotechnol, 4, 377-399 (2008). Tammy Y. Olson and Jin Z. Zhang, Structural and optical properties and emerging applications of metal nanomaterials, J. Mater. Sci. Technol, 24, 443-446 (2008). C. Shi, Y. Zhang, C. Gu, B. Chen, L. Seballos, T. Olson and J. Z. Zhang, Molecular fiber sensors based on surface enhanced raman scattering (SERS), J. Nanosci. Nanotech, 9, 2234-2246 (2008). F. Wu, J. Zaug, C. E. Young and J. Z. Zhang, Pressure-induced phase transition in Thiol-capped CdTe Nanoparticles, J. Nanosci. Nanotech, 8, 6528-6532 (2008). A. Escobedo Morales, R. Aceves, U. Pal and J. Z. Zhang, Low temperature photoluminescence characteristics of chemically synthesized indium doped zinc oxide nanostructures, J. Nanosci. Nanotech, 8, 6538-6544 (2008). Adam M. Schwartzberg and Jin Z. Zhang, Novel Optical Properties and Emerging Applications of Metal Nanostructures, J. Phys. Chem. C, 112, 10323-10337 (2008). Tzarara Lopez-Luke, Abraham Wolcott, Li-ping Xu, Shaowei Chen, Zhenhai Wen, Jinghong Li, Elder De La Rosa and Jin Z. Zhang, Nitrogen-Doped and CdSe Quantum-DotSensitized Nanocrystalline TiO2 Films for Solar Energy Conversion Applications, J. Phys. Chem. C, 112, 1282-1292 (2008). T. Lopez-Luke, A. Wolcott, Liping Xu, Shaowei Chen, Zhenhai Wen, Jinghong Li, Elder de La Rosa-Cruz and J. Z. Zhang, Nitrogen doped and CdSe quantum dot sensitized nanocrystalline TiO2 films for solar energy conversion applications, J. Phys. Chem. C, 112, 1282-1292 (2008). Tammy Y. Olson, Adam M. Schwartzberg, Christine A. Orme, Chad E. Talley, Breanna O’Connell and Jin Z. Zhang, Hollow Gold-Silver Double-Shell Nanospheres: Structure, Optical Absorption, and Surface-Enhanced Raman Scattering, J. Phys. Chem. C, 112, 6319-6329 (2008). Geng Wang, Da Chen, Hao Zhang, Jin Z. Zhang and Jinghong Li, Tunable Photocurrent Spectrum in Well-Oriented Zinc Oxide Nanorod Arrays with Enhanced Photocatalytic Activity, J. Phys. Chem. C, 112, 8850-8855 (2008). Marites P. Melancon, Wei Lu, Zhi Yang, Rui Zhang, Zhi Cheng, Andrew M. Elliot, Jason Stafford, Tammy Olson, Jin Z. Zhang and Chun Li, In vitro and in vivo targeting of hollow gold nanoshells directed at epidermal growth factor receptor for photothermal ablation therapy, Mol. Cancer Ther, 7, 1730-1739 (2008). Chao Shi, Yi Zhang, Claire Gu, Leo Seballos and Jin Z. Zhang, Manipulation and light-induced agglomeration of carbon nanotubes through optical trapping of attached silver nanoparticles, Nanotechnology, 19, 215304/1-215304/6 (2008). J. Z. Zhang and C. Noguez, Plasmonic optical properties and applications of metal nanomaterials, Plasmonics, 3, 127150 (2008). Chao Shi, Yi Zhang, Claire Gu, Leo Seballos and Jin Z. Zhang, Low concentration biomolecular detection using liquid core photonic crystal fiber (LCPCF) SERS sensor, Proc. SPIE, 6852, 685204/1-685204/8 (2008). A. Wolcott, W. A. Smith, T. R. Kuykendallc, Y. P. Zhao and J. Z. Zhang, Photoelectrochemical generation of hydrogen from water splitting based on dense and aligned TiO2 nanorod arrays, Small, 5, 104-111 (2008). Leo B. Seballos, Raman and surface enhanced raman scattering of biomolecules and materials for hydrogen storage and delivery. (D)