PRESCRIPTION ORDER FOR PATIENT CONTROLLED ANALGESIA (PCA) PUMP PATIENT INFORMATION Name: Date of Birth: (Last Name, First Name) Male Gender: (dd-mmm-yyyy) Female Address: City: Postal Code: **Patient Identifier is required upon delivery under Narcotics Safety and Awareness Act ** (http://www.health.gov.on.ca/en/public/programs/drugs/ons/) Health Card Number (Recommended): or Check One Identifier: Driver’s License Passport Birth Certificate Citizenship Card Military Other: No. on Identifier: or Exempt/Unable to Supply Identification to Prescriber Specify Reason: Note: If patient is unable to supply identification, the medication must be received/delivered to person directly Allergies: Discontinue all previous narcotic orders Medication: Morphine Concentration: Hydromorphone Other: mg/mL (The higher the concentration, the smaller the infusion volume for subcutaneous so site will last) Route: Subcutaneous Other: (If intravenous, basal rate volume must be minimum 0.5mL/hr) Infusion Rate: Minimum mg/hr; Maximum Breakthrough Bolus Doses: Minimum mg/hr; Starting mg; Maximum Breakthrough Bolus Interval: Every min prn Maximum: mg/hr mg; Starting mg doses/hr May increase both basal and bolus rates of infusion by mg each for pain greater than or greater than breakthrough used over 24 hour period AND notify MD/NP Reservoir Size: 100 mL Other: Total Quantity of Reservoirs: Dispense at each time: mL 10 (ten) 2 (two) /10 Other: Other: PHYSICIAN (Prescriber, please sign and date prescription) Name (PRINT): CPSO No. (Required): Address: Tel: After Hours Tel: Fax: Signature: Date: (dd-mmm-yyyy) Prescription Order for Patient Controlled Analgesia (PCA) Pump November 2015 Page 1 of 2 How-To-Guide – Starting a Continuous Subcutaneous Infusion Step 1: Step 2: Step 3: Determine the 24-hour oral dose of narcotics by adding up the amount of controlled-release per 24-hour and the average amount of breakthroughs used in a 24 to 48 hour period Determine which subcutaneous (subcut) medication you want to use (hydromorphone vs. morphine) Convert all current oral (PO) opioids to your drug of choice (in PO form first) Drug PO dose Ratio to morphine* Morphine 10 mg -Codeine 100 mg 10 : 1 Oxycodone 5 mg 1:2 Hydromorphone 2 mg 1:5 *When switching from one opioid to another, reduce dose by 20% - 50% for incomplete cross tolerance (30% reduction generally used) Morphine dose mg PO/24 hr** Transdermal (TD) fentanyl dose mcg/hr every 72 hr 25 – 59 12 60 – 134 25 135 – 179 37 180 – 224 50 225 – 269 62 270 – 314 75 315 – 359 87 360 - 404 100 **Does not require 30% reduction as already done in table **When switching from TD fentanyl to subcut infusion, discontinue patch and start pump 12 hr later. Rely on breakthrough doses to get patient through **Start PCA pump when next long acting opioid is due Example: Patient on 6 mg HydromorphCONTIN BID + Morphine 5 mg Breakthrough x2/day – switching to Hydromorphone = 12 mg Hydromorphone PO/24 hr + 10 mg Morphine PO/24 hr = 12 mg Hydromorphone PO/24 hr + 10 mg Morphine = 2 mg Hydromorphone = 1.4 mg Hydromorphone PO/24 hr (30% for cross tolerance) = 13.4 mg Hydromorphone PO/24 hr total daily dose Step 4: Step 5: Step 6: Step 7: Convert the 24 hour oral dose into equivalent subcut dose. This is a 2 : 1 ratio (PO : Subcut). Divide the total daily PO dose by 2 to get the subcut dose/24 hour. Divide the 24 hour subcut dose by 24 hours to get the hourly dose. The pump infuses hourly doses in milligrams per hour. Determine the breakthrough dose. The breakthrough dose is 10% of the total daily subcut dose. The breakthrough can be infused every hour, or alternatively broken into intervals of every 15 or 30 minutes Determine the concentration on the subcut medication you are using. The appropriate drug concentration is dependent on the dose being used. (Minimum infusion rate: 0.1 mL/hr; Maximum: 1 mL/hr) Standard Concentrations 1 mg/mL 2 mg/mL 10 mg/mL 50 mg/mL Recommended Subcutaneous Rates 0.1 – 2 mg/hour 2 – 5 mg/hour 2 – 30 mg/hour 10 – 150 mg/hour Adapted from: Pallium Canada. (2013). The Pallium Palliative Pocketbook: A peer-reviewed, referenced resource. Prescription Order for Patient Controlled Analgesia (PCA) Pump November 2015 Page 2 of 2