EJISST2008 June 8~10
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TABLE OF CONTENTS
MESSAGES ................................................................................................................ 11
MINSTER OF HIGHER EDUCATION AND STATE FOR SCIENTIFIC RESEARCH, EGYPT .. 12
FIRST UNDERSECRETARY FOR CULTURAL AFFAIRS AND SCIENTIFIC MISSIONS,
MINISTRY OF HIGHER EDUCATION AND STATE FOR SCIENTIFIC RESEARCH, EGYPT . 13
AMBASSADOR OF THE ARAB REPUBLIC OF EGYPT TO JAPAN .................................... 14
CULTURE COUNSELOR, CULTURE, EDUCATION AND SCIENCE BUREAU, THE EMBASSY
OF THE ARAB REPUBLIC OF EGYPT IN JAPAN ............................................................ 15
CULTURAL ATTACHÉ, CULTURE, EDUCATION AND SCIENCE BUREAU, THE EMBASSY
OF THE ARAB REPUBLIC OF EGYPT IN JAPAN ............................................................ 16
PATRONS AND HONORARY ADVISORS .......................................................... 17
ORGANIZATION COMMITTEE .......................................................................... 19
JOINT PROJECTS AND INVITED TALKS ......................................................... 22
- EJUST：A Breakthrough University of Science and Technology - .................. 23
Heat-Directed Composite Materials: From Concept to Aerospace Applications
.............................................................................................................................. 23
Conservation Activities of "Egyptian-Japanese Mission for the Mastaba Idout"
(2005-2007).......................................................................................................... 24
Stability Investigation of Mother Rock in a Pharaonic Mastaba (Saqqara) for its
Conservation of Mural Paintings......................................................................... 24
Towards academic exchange and cooperation between NWRC and TU ............ 25
Seismological Observation in and around the Southern Part of the Gulf of Suez,
Egypt .................................................................................................................... 25
A window to the ancient Earth: Pan-African ophiolites of Proterozoic age from
Southeastern Desert, Egypt .................................................................................. 26
Future World Water Assessment through System Dynamics ............................... 26
Liver Cancer in Egypt and an Experience of Collaboration in Cancer Treatment
.............................................................................................................................. 27
MEMS/MS and Assembly as Key Components and Technology for Advanced
System .................................................................................................................. 27
Nucleosides, nucleotides and nucleic acids: chemistry and biology ................... 28
Characterization and Expression of the Insect-Specific Scorpion Neurotoxins for
Pest Control ......................................................................................................... 29
Tumor Necrosis Factor Receptors on Lymphoma Cells in Enzootic Bovine
Leukosis................................................................................................................ 30
Optical Sum Frequency Microscopy for Botanical Analysis ............................... 30
Atomic scale flattening of oxide thin film formed on metals ................................ 31
Possible applications of solid electrolyte to lithium secondary battery, sensor
and supercapacitor .............................................................................................. 31
Electrostatic precipitation, as an important environmental technology ............. 32
Experience with Plastic Surgery In Ain Shams University and prospects of
cooperation with the Japanese Universities ........................................................ 33
EJISST2008 June 8~10
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ABSTRACTS.............................................................................................................. 34
SESSION 1: NANOTECHNOLOGY MATERIALS, PROCESS AND PRODUCTS ................ 35
Design of low Young’s modulus Ti alloys with high UTS for biomedical
applications .......................................................................................................... 35
Characterization of Electrodeposited Hydroxyapatite Coating on Nanoporous
Anodized Titanium ............................................................................................... 35
Electrochemical behavior of anodic film on AZ31 mg alloy in 1M NaOH solution
.............................................................................................................................. 36
Ion Dynamics and Giant Dielectric Constant in Pb1-xSnxF2 Solid Solutions....... 36
Investigation of Self Assembly Monolayer (SAM) by using Second Harmonic
Microscopy (SHM) and Sum Frequency Microscopy (SFM) .............................. 37
Application of Pulsed Power Technology to Water-Solubilization of Carbon
Nanotubes ............................................................................................................ 37
Novel pH-Sensitive Nanospheres for Colon-Specific Drug Delivery .................. 38
Preparation of new nanocomposite materials based on layered double hydroxide
.............................................................................................................................. 38
Formation of SiC MMC layer on Al alloys by friction stir processing ................ 39
Iterative Learning Control based nonlinear friction modeling in fast and precise
positioning control ............................................................................................... 39
Ion Transport Behavior in Diffusion Layer of New Designed Ion ExchangeMosaic Composite Polymer Membrane ............................................................... 40
SESSION 2: NEW AND RENEWABLE ENERGY .......................................................... 41
-SOLAR, -WIND, AND BIO-ENERGY ........................................................................... 41
IMPACTS OF WIND FARMS ON THE POWER SYSTEM QUALITY AND
STABILITY ........................................................................................................... 41
A Methodology for Designing and Evaluating Biomass Utilization Networks ... 41
DESIGN OF RENEWABLE ENERGY SYSTEM IN AN EGYPTIAN SITE .......... 42
Laser Induced Magnesium Oxide Reduction for Renewable Energy Cycle with
Solar Power ......................................................................................................... 42
Electrochemical deposition of indium sulfide thin films for solar cell application
.............................................................................................................................. 43
Development of a DMFC Employing a Novel Electrode Structure ..................... 43
Intelligent Wind Turbine ...................................................................................... 44
SESSION 3: MANUFACTURING AND QUALITY - FABRICATION OF ELECTRONIC
COMPONENTS ........................................................................................................... 45
Application of the repulsive type magnetic bearing technology based on digital
control implementation for manufacturing a micro mass measurement system.. 45
Development of low noise RF front–end for ultra-wideband (UWB) systems on
0.18um CMOS Technology .................................................................................. 45
Noise Reduction of Randomly Switched DC-DC Converters by Digital Controller
.............................................................................................................................. 46
SESSION 4: BIOTECHNOLOGY - AGRICULTURE - FOOD (1) ...................................... 47
Indirect 15N isotope techniques for estimating rice N uptake from poultry manure
and sewage sludge ............................................................................................... 47
Towards Integrated Water Management for Sustainable Agricultural
Development in North Sinai, Egypt ..................................................................... 47
Application of Congo red agar to detect Streptococcus dysgalactiae subsp.
dysgalactiae isolated from diseased fish.............................................................. 48
Characterization of Cytochrome P450 CYP1A in Ungulates .............................. 49
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Nanotechnology meets plant biotechnology: Carbon Nanotubes deliver DNA and
elicit biochemical responses in plants ................................................................. 49
Reconstruction of Iron-Oxidation Enzyme System from the Rusticyanin, c-Type
Cytochrome and aa3-Type Cytochrome c Oxidase of Sulfur-Grown
Acidithiobacillus ferrooxidans ATCC 23270 ....................................................... 50
First Characterization and Emergence of SHV-60 in Raw Milk of a Healthy Cow
in Japan................................................................................................................ 50
Taxonomic study of the subgenus Lasioglossum s. str. of the genus Lasioglossum
(Hymenoptera, Halictidae) in Japan ................................................................... 51
Anti-babesial ellagic acid rhamnosides from the bark of Elaeocarpus parvifolius
.............................................................................................................................. 51
Identification and expression analysis of a novel interleukin 8(IL-8)in
carp(Cyprinus carpio, L) ..................................................................................... 52
Functional characterization of the promoter of a juvenile hormone-regulated
gene, Vitellogenin-2, from the cockroach Periplaneta americana ...................... 52
Studies on lactic acid production from xylan by novel strains of marine lactic
acid bacteria, Halolactibacillus miurensis .......................................................... 53
Studies on lactic acid production from polysaccharides by novel lactic acid
bacteria ................................................................................................................ 53
Effects of anti-oxidative nutrients on unloading-mediated expression of
atrogenes .............................................................................................................. 54
Monitoring Changes in the Arthropods Biodiversity in Satoyama area with
special reference to Carabid Beetles as Bioindicators ........................................ 54
Performance of the Cotton Leaf Worm Spodoptera littoralis (Boisd.)
(Lepidoptera: Noctuidae) fed Cotton Plant Leaves Gossypium barbadens
(Malvaceae) grown under Ambient 350 ppm and Enriched 700 ppm CO2
Regimes ................................................................................................................ 55
Dynamics of carbon and nitrogen derived from 13C and 15N dual-labeled
compost in continuously application in a vegetables soil .................................... 55
Utilization of biotechnology for improving abiotic stresses in cereals ............... 56
Fermented milk product prepared with probiotic bacteria affects the onset of
obesity in rats ....................................................................................................... 56
SESSION 5: BIOTECHNOLOGY - MEDICINE (1) ........................................................ 57
Branchial Sodium- Potassium ATPase enzyme activity of Mitochondrion-rich
cells In Mozambique tilapia in response to Osmotic changes ............................. 57
Monocarboxylate Transporter 1 (MCT1) in the Gastrointestinal Tract of
Ruminants ............................................................................................................ 57
Pathological study on the scuticociliatosis affecting natural and farmed Bastard
Halibut (Paralichthys olivacus)in Tottori prefecture, Japan .............................. 58
In Vitro Expression of Natriuretic Peptides in Cardiomyocytes Differentiated
from Monkey Embryonic Stem Cells .................................................................... 58
Ki-67, p53 and Epidermal Growth Factor Receptor expression in early laryngeal
cancer treated with radiotherapy......................................................................... 59
Evidence of linkage on chromosomes 4q28 and 7q in a genome-wide linkage
scan for comitant strabismus susceptibility loci among Japanese families ......... 59
Molecular Characterization of PVL-Positive Staphylococcus aureus isolated
from Egypt ............................................................................................................ 60
Deep brain simulation for Parkinson disease ...................................................... 60
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Analyses of the propagation of canine distemper viruses (CDVs) in HmLu
hamster cells ........................................................................................................ 61
Characterization of a minor human NK cell sub-population, CD56dim16-cells... 61
Molecular epidemiological study on Hepatitis viruses in Ismailia Egypt ........... 62
AP-1 and NF-κB are key regulators of Toll-Like Receptor 3 signaling pathway:
an in silico prediction .......................................................................................... 62
Identification of cells that have hematopoietic activity in the placenta of mouse
embryo.................................................................................................................. 63
Effect of local soft x-ray irradiation on rat skin: to establish radiation-impaired
wound healing model ........................................................................................... 63
The Detection of Autophagy and Apoptosis in Pancreatic Beta Cells to
Investigate the Contribution of Autophagy for Islets to Survive During Isolation
and Transplantation ............................................................................................. 64
The role of PROPELLER Diffusion Weighted Imaging and Apparent diffusion
coefficient in the diagnosis of sellar and parasellar lesions................................ 64
Migration inhibitory factor and neuclear factor kabba B expression after
laparotomy and pneumoperitoneum .................................................................... 65
Species differentiation of eimerian oocysts in farms where no clinical coccidiosis
is noted ................................................................................................................. 65
Some morphological studies on the visual system of albino and pigmented rat . 66
The significance of rDNA sequence and lipopolysaccharide in the pathology and
biotechnology of Agrobacterium species ............................................................. 66
SESSION 6: BIOTECHNOLOGY - PHARMACY ............................................................ 67
Total Synthesis of Kahalalide F Toward Elucidation of the biological function
concerning the oceanic production reason of active peptides which are recently
discovered ............................................................................................................ 67
Plasmodium falciparum Guanosine Monophosphate Kinase:A New Target for
the Development of Anti-Malarial Drugs ............................................................ 67
Prolongation of residence time of liposome by surface- modification with mixture
of hydrophilic polymers ....................................................................................... 68
Proteome approach for identification of Schistosomiasis japonica vaccine
candidate antigen ................................................................................................. 68
Two new biologically active compounds from marine fungi ............................... 69
A novel approach using functional peptides for efficient nasal absorption of
insulin................................................................................................................... 69
Highly sensitive and selective HPLC method with peroxyoxalate
chemiluminescence detection for the determination of doxorubicin and its
metabolite doxorubicinol in rat plasma ............................................................... 70
Antitumor hydrolysable tannins from wildly growing plant, Tamarix nilotica, in
the Egyptian oases ............................................................................................... 70
Amidophosphane–Copper(I)-Catalyzed Asymmetric Conjugate Addition of
Dialkylzincs to Racemic 6-Substituted Cyclohexenones to Form 2,5-Di- and
2,2,5-Trisubstituted Cyclohexanones ................................................................... 71
MODULATION OF GENE EXPRESSION BY HUMAN CYTOSOLIC tRNase ZL
THROUGH SMALL NONCODING RNA ............................................................ 71
Synthesis and properties of 1’-disubstituted Nucleoside Analogues ................... 72
Modulatory effects of 5-Fluorouracil on the rhythmic expression of circadian
clock gene: a possible mechanism for chemotherapy-induced circadian rhythm
disturbances ......................................................................................................... 72
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Importance of D-Amino Acid Oxidase Enzyme in Biotechnology ....................... 73
The effects of extracellular acidic environments on T-cell differentiation .......... 73
New sesquiterpene lactones from Daucus glaber (Forssk.) Tell. F. Umbelliferae
.............................................................................................................................. 74
Role of β-Hydroxy--Trimethylammonium Butyrate and Ubiquinone in
Combating the Deteriorative Effect Induced by CCl4 in Rat’s Liver .................. 74
Diagnosis of human malaria parasites in mosquitoes ......................................... 75
Total Synthesis of Aza Analogues of Flustramide alkaloids by Using Aza PausonKhand Reaction .................................................................................................... 75
Utilization of cell penetrating peptides for enhancing intracellular delivery of
nucleic acids encapsulated into liposomes: Octaarginine versus octalysine ...... 76
A new Route to Synthesis of Biologically Active Azaindoles ............................... 76
Recombinant Human Growth Hormone (rHGH) Production ............................. 77
SESSION 7: HUMAN SCIENCE.................................................................................. 78
For Interchange and Collaboration between Islamic Economics and Buddhist
Economics ............................................................................................................ 78
Policy Networks and Public Policy Making Process: A Comparative Analysis to
the Education Policy Reforms and the ODA Policy Reforms in Japan during the
1980s and the 1990s............................................................................................. 78
Social policies in Egypt and how subsidies system can be rationalized to benefit
the poor ................................................................................................................ 79
Environmental Security in the International Politics: A Comparative Study
between Japanese and American Policies ........................................................... 79
A Study about Interference of Mother Language and Misuse Analysis in the
Second Language Acquisition. ............................................................................. 80
中世文学における地獄と浄土の夢.................................................................. 81
宮沢賢治の文学における「孤独感」.............................................................. 81
Japanese Studies at Kansai University: Globalizing Our Campus ..................... 82
Japanese Language Culture - Language ............................................................. 82
Modern Literature and Gender- Japanese Literature ......................................... 83
Higher Education Privatization and the Planning for Educational Reform:
Malaysia as a Case Study 1996-2006 .................................................................. 83
福沢諭吉とムハンマド･アブドウの教育思想................................................ 84
“Continuity and Discontinuity in Japanese Foreign Policy toward the Middle
East: The Persian Gulf Wars” as a case study .................................................... 84
Japanese demonstratives ..................................................................................... 85
イスラム教．仏教における死後の世界.......................................................... 85
日本語とアラビア語の慣用表現の意味と概念的メタファーのメカニズム
.............................................................................................................................. 86
SESSION 8: BIOTECHNOLOGY - AGRICULTURE - FOOD (2) ...................................... 87
Microbiological, Chemical, sensory and shelf life evaluation of sliced salmon
treated with salts of organic acids ....................................................................... 87
Colistin susceptibility, pharmacokinetics, and residues in broilers and laying
hens ...................................................................................................................... 87
Implementation Degree of Agricultural Decisions in the farm Level: Comparison
Study between Egypt and Japan........................................................................... 88
EVALUATION OF NATURAL ANTIOXIDANTS EXTRACTED FROM
DIFFERENT AGRO-INDUSTRIAL BY PRODUCTS.......................................... 88
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Regulation of developmental timing by transcription factors in Drosophila
melanogaste ......................................................................................................... 89
A 450-kb B chromosome in a filamentous ascomycete Nectria haematococca
mating population I (anamoph, Fusarium solani f. sp. cucurbitae) .................... 89
Expression and functions of retinol binding protein 4 in bovine adipocytes ....... 90
New Selective cytotoxic compounds from zizyphus spina christi L ..................... 90
Bio-surface modification of some oxide minerals and its application in minerals
separation ............................................................................................................ 91
Biotechnological studies on halophilic bacteria isolated from Egyptian salt lakes
.............................................................................................................................. 91
Effect of high temperature on sex differentiation and germ cell population in
medaka, Oryzias latipes ....................................................................................... 92
Immunohistochemical investigation for arthropod brain design and the
functional relationship to the mid gut system ...................................................... 92
Characterization of a novel dehalogenase involved in 2-chloroacrylic acid
metabolism in Pseudomonas sp. YL ..................................................................... 93
Establishment of regeneration and transformation protocol for Anthurium
andreaum ............................................................................................................. 93
Development of live attenuated vaccine for Edwardsiella tarda infection in fish
.............................................................................................................................. 94
Microbiological Quality of Some Egyptian Meat Products ................................. 94
SESSION 9: BIOTECHNOLOGY - MEDICINE (2) ........................................................ 95
Gene Expression Profiles in High and Low Metastatic Potential Lung Cancer
Cell Lines, a cDNA Microarray-Based Study ...................................................... 95
An efficient in-vitro model for the study of natural Hepatitis C virus infection .. 96
Increased Intestinal Endotoxin Absorption during Enteric Nematode but not
Protozoal Infections through a Mast Cell-Mediated Mechanism ........................ 96
The role of membrane type1- matrix metalloproteinase ( MT1-MMP) in cancer
ivasion and metastasis ......................................................................................... 97
Chk1 is a histone H3-T11 kinase that regulates DNA damage-induced
transcriptional repression .................................................................................... 97
Virological and clinical implication of core promoter C1752/V1753 and
T1764/G1766 mutations in hepatitis B virus genotype D infection ..................... 98
Facial Nerve Injury induces activation of NF-kB in rat facial nucleus ............... 98
Effect of two housing systems and stocking density on White New Zealand Rabbit
.............................................................................................................................. 99
Treatment of scaphoid nonunion with dorsal transplantation of vascularized
bone grafts ........................................................................................................... 99
Comparative Study between Open and Laparoscopic Distal Pancreatectomy . 100
Caspase activation role in the antiviral treatment response in chronic hepatitis C
virus infection..................................................................................................... 100
The role of CFTR protein in intestinal epithelial cell function and cystic fibrosis
............................................................................................................................ 101
Expression of cytokine genes in head kidney and spleen cells of Japanese
flounder infected with N. seriolae ...................................................................... 101
SESSION 10: HEALTH - CLINIC AND PRACTICE (1-2) ............................................ 102
Photoprotective effects of chemical peeling agents against ultraviolet-induced
photoaging in hairless mice ............................................................................... 102
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Predictors of short and long-term survival after adult living donor liver
transplantation ................................................................................................... 102
Immunohistochemical expression of ATX and AGK in Prostate Cancer with
relevance to Clinicopathological parameters .................................................... 103
Human scavenger receptor class B type I is regulated by activators of
Peroxisome proliferators-activated receptor- in hepatocytes .......................... 103
The Sex Differences of Cerebrospinal Fluid levels of Interleukin-8 and
Antioxidants in Asphyxiated Newborns ............................................................. 104
Novel role of HMG-CoA reductase inhibitor in keratinocyte proliferation and
migration ............................................................................................................ 104
Molecular biological studies on cancer gene therapy: regulation of apoptosis
and metabolosim ................................................................................................ 105
Pediatrics cardiology ......................................................................................... 105
Evaluation of Coronary Calcium Score by Multidetector Computed Tomography
in Relation to Endothelial Function and Inflammatory Markers in Asymptomatic
Individuals.......................................................................................................... 106
Utilization of Polymethyle-methacrylate (PMMA) interposition as an alternative
to the different modalities of cervical interbody fusion for treatment of single
level cervical disc disease .................................................................................. 106
Various reconstructive modalities for diabetic foot ulcer ................................. 107
Two different techniques for donor hepatic transection: CUSA with Bipolar
cautery versus CUSA with TissueLink™. A randomized controlled trial ......... 107
SESSION 11: HEALTH DIAGNOSIS AND HEALTH MANAGEMENT (1) ..................... 108
Research on genetics of respiratory diseases in Japanese and Egyptian
populations, Lung mucus , regeneration with HGF and stem cells ................... 108
Mechanisms of Enhancement of TRAIL Tumoricidal Activity Against Human
Cancer Cells of Different Origin by Dipyridamole ........................................... 108
Bacteriocin production in the compost process ................................................. 109
Percutaneous Treatment of HCC ....................................................................... 109
NERVE TRANSFER TO DELTOID MUSCLE USING THE MOTOR BRANCHES
OF THE TRICEPS MUSCLE AFTER UPPER BRACHIAL PLEXUS AVULSION
INJURIES ........................................................................................................... 110
Analyses of Fluourotelomer alcohols (FTOHs) in surface waters using Gas
chromatography- Mass spectrometry (GC-MS) ................................................ 110
SESSION 12: HEALTH DIAGNOSIS AND HEALTH MANAGEMENT (2) ..................... 111
Endoscopic Ultrasound Fine Needle Aspiration (EUS-FNA) and Endoscopic
Retrograde Cholangiopanreatography (ERCP) Brush Cytology in Diagnosis of
Biliary and Pancreatic Duct Strictures.............................................................. 111
A New Era for the Dry Eye Diagnosis ............................................................... 111
Predictive factors of worsening of esophageal varices after balloon-occluded
retrograde transvenous obliteration in patients with gastric varices ................ 112
Chemoprevention and theraputic treatment of basal cell carcinoma (BCC) .... 112
SESSION 13: INFORMATION & COMMUNICATIONS TECHNOLOGY(ICT) AND
SUPERCOMPUTING .................................................................................................. 114
Embedded Systems Design and Technology ...................................................... 114
Material Classification using Spectral Reflectance Information....................... 114
Meta-Heuristics Programming: Memetic Programming................................... 115
Design and Evaluation of Data-Parallel Algorithms on a Matrix Processor ... 115
Cross-Layer Design for Power Efficient Wireless Ad Hoc Networks................ 116
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Access Point Allocation in Indoor Environments for Wireless Mesh Networks 116
Comparative Study between Three Types of Down-Conversion Mixers Giving
Emphasis on Sampling Mixer for Wireless Applications ................................... 117
Voice over IP-Networks Performance Analysis and Enhancement ................... 117
Router- based Defense against DDoS Attack .................................................... 118
Two models for electro-magnetic wave amplifier utilizing traveling electron
beam ................................................................................................................... 118
A Dynamic Channel Assignment Problem for Wireless Internet-access Mesh
Networks ............................................................................................................ 119
Automatic Building of New Field Association Word Candidates Using Search
Engine ................................................................................................................ 119
An Automatic Filtering Method for Field Association Words by Deleting
Unnecessary Words ........................................................................................... 120
Contents Aware Network Security for JPEG 2000 Encoded Images ................ 120
Towards a novel all-optical switch, design, fabrication and characterization . 121
A method to improve the precision of search engines using Ranking of Field
Association terms using Co-word analysis ........................................................ 121
Mutual Intention in Human Robot Teammate Situations .................................. 122
SESSION 14: INFORMATION & COMMUNICATIONS TECHNOLOGY(ICT) ............... 123
Decision Support System for Ubiquitous Learning Environments .................... 123
Security Analysis of a Crypto-Compression Algorithm for Medical Images ..... 123
An Intelligent Recommender System Using Particle Swarm Optimizer (PSO) and
Artificial Immune System (AIS) .......................................................................... 124
An Intelligent Framework for Image Understanding ........................................ 124
Participation Enhancement in Urban Planning, Decision-Making Process Using
Virtual Reality Techniques ................................................................................. 125
Reconstruction algorithms for tomographic imaging ........................................ 125
Load Voltage Regulation and Line Loss Minimization of Loop Distribution
System Using UPFC .......................................................................................... 126
Automatic Human Body Modeling for Vision-Based Motion Capture .............. 126
Face Recognition under varying illumination using self-organizing Map ........ 126
Architecture and Synthesis of a Two-Fingered Micro-Nano Hybrid Manipulator
............................................................................................................................ 127
Blind image and video super-resolution based on mixed-norm ........................ 127
Earthquake Onset Detection using Spectro-Ratio on Multi-Threshold TimeFrequency Sub-Band .......................................................................................... 128
Multiple Object Tracking Using Local PCA...................................................... 128
Similarity Measurement Approaches Using Association Keywords .................. 129
A new Algorithm based on Geometric Analysis for Task Scheduling in
Multiprocessor systems ...................................................................................... 129
Computer-Aided Diagnosis System for Liver Cancer Using Multi Slice CT
images ................................................................................................................ 130
Video Coding Using Motion Estimation and Compensation Techniques .......... 130
Efficient Face Detection and Recognition System ............................................. 131
Automatic Text categorization for Arabic Documents....................................... 131
A STUDY FOR AUTOMATED VISUAL INSPECTION OF TEXTILE
MATERIALS BY IMAGE PROCESSING ........................................................... 132
SESSION 15: CIVIL AND ENVIRONMENTAL ENGINEERING-EARTHQUAKE
GEOTECHNICAL, AND AIR POLLUTION .................................................................... 133
EJISST2008 June 8~10
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DESIGN AND CONSTRUCTION CHALLENGES OF LONG SPAN BRIDGES
CONCEPT IN EGYPT ....................................................................................... 133
High Performance Ferrocement-Grouted Mortar Composites for Sustainable
Development of Construction Materials ............................................................ 133
Innovative Design of Calibration Chamber for Geotechnical Physical Modeling
............................................................................................................................ 134
Groundwater seepage into an abandoned mining site in Egypt ........................ 134
Evaluation of Geo-environmental Impact for the Application of Industrial Waste
Materials in Geotechnical Problems ................................................................. 135
Geophysical Structures of Several Geothermal Fields in Egypt and Conceptual,
Numerical Models of Their Geothermal System ................................................ 135
Chemical compounds effect on critical shear stress and erodability of volcanic
ash soil ............................................................................................................... 136
Numerical Simulation of Debonding Failure of Reinforced Concrete Beam
Strengthened with Externally Bonded FRP and Development of Rational
Prediction Method ............................................................................................. 136
Advanced bifurcation analysis of truss structures ............................................. 137
Borehole ground penetrating radar technique for subsurface fracture
characterization and its application to geothermal energy extraction .............. 137
Evaluation of Crack Elongation Performance of UHP-SHCC as a Surface
Repairing Material............................................................................................. 138
Modifed linear viscoelastic model for elimination of the tension force in the
linear viscoelastic .............................................................................................. 138
SEISMIC ANALYSIS OF CABLE-STAYED BRIDGE STEEL TOWERS ........... 139
Shear Cracking Behavior in Reinforced Concrete Members ............................ 139
Using Ground Penetrating Radar for Environmental and Archaeological
Investigation in Egypt ........................................................................................ 140
Recoverability of Existing Bridge Columns under Moderate to Strong
Earthquake ......................................................................................................... 140
Hydrous peridotite with Ti-rich chromian spinel "a low-temperature peridotite
overlying slab" ................................................................................................... 141
STUDY OF THE BEHAVIOR OF PILE GROUPS UNDER LATERAL LOADING
............................................................................................................................ 141
CRACK DETECTION in CONCRETE STRUCTURES – THEIR
STRENGTHENING USING CFRP .................................................................... 142
Inverse CFD Modeling as a Tool to Identify Pollution Source Locations in
Outdoor Environments: Application of Reversed Time Marching Method ....... 142
Numerical Predictions of Pollutant Dispersion near Buildings: Effect of Cell
Geometry ............................................................................................................ 143
Regional Environment Simulator: Atmosphere, land surface Ocean Interactions
............................................................................................................................ 143
SESSION 16: CIVIL AND ENVIRONMENTAL ENGINEERING – .................................. 144
AIR POLLUTION ...................................................................................................... 144
Analysis on Urban Expansion Issues of Developing Cities in Egypt................. 144
Distributed Water Balance Model in Watershed Coupled With River Flow
Routings ............................................................................................................. 144
Preparation of Carbon Coated W18O49 with Iron and Its Photoactivity under
Visible Light ....................................................................................................... 145
Observation of Coastal Morphology Using X-band Radar ............................... 145
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Homogenization theory application as up-scaling technique for the hydrological
parameters in the arid and semiarid areas, Wadi Assiut as case study ............ 146
Laboratory tests on the occurrence of fluoride rich groundwater of Tono area,
Japan .................................................................................................................. 146
Stiffness Degradation Process during Liquefaction Applied to the Port Island
Site during the 1995 Hyogo-ken Nambu (Kobe) Erathquake ............................ 147
“The habitus-Field networking model” an alternative subcontracting
arrangement in Japan: Evidence from subcontracting clusters in Higashiosaka
district ................................................................................................................ 147
SESSION 17: MECHANICAL ENGINEERING ............................................................ 148
Laser Welding of High strength Steel ................................................................ 148
Numerical Simulation of a Hydrogen Leakage Jet ............................................ 148
Modeling of fatigue performance of structures strengthened with externally
bonded CFRP composites .................................................................................. 149
Control of Flexible Manipulators Using Visual Data ....................................... 149
Design and Simulation of a Tactile Sensor for Soft-Tissue ............................... 150
Circular Path Estimation of a Rotating Four-Legged Robot Using a Hybrid
Genetic Algorithm LSM ..................................................................................... 150
Influence of Micro-Bubbles on the Heat Transfer and Pressure Drop of Water
Flows in A Helical Pipe ..................................................................................... 151
Spray Behavior near the Nozzle of a DISI Multi-Hole Injector Using Phase
Doppler Anemometer ......................................................................................... 151
Transient Spray from Port Fuel Injector ........................................................... 152
Punching Shear Strength of Concrete Slab Strengthened with FRP under Various
Environments ..................................................................................................... 152
Assuming the Crystallization Age and Thermal events affected the Basement
Complex, Abu Zenima area West-Central Sinai, Egypt ..................................... 153
Fabrication of aluminum nitride coatings by plasma spraying ......................... 153
On the discrepancies among seismic wave velocities in soft sediments obtained
using different measuring techniques ................................................................ 154
APPENDIX 1: SYMPOSIUM VENUE .................................................................. 155
APPENDIX 2: SYMPOSIUM SCHEDULE.......................................................... 159
APPENDIX 3: PRESENTER LIST ....................................................................... 196
EJISST2008 June 8~10
MESSAGES
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EJISST2008 June 8~10
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Dr. Hany Helal
Minster of Higher Education and State for
Scientific Research, Egypt
It is my pleasure to address this statement to the Egyptian professors
and postgraduate students on the isles of Japan at the present time.
Acquiring knowledge has been and will always be the apex of man’s
activities. No better example than where you all are now in Japan; a
country where the first and utmost capacity and resource is knowledge.
For long, since 1862, Egypt and Japan have been wondering on how to
prosperous and able to achieve well being for their country people! Japan
with its modern industrial and economical leadership since the early
seventies of the last century has been Mecca for more than 1300 Egyptian
graduates and well above 400 postgraduate right now. It is through you
and your determination, Egypt aims to learn the good lessons of Japan in
how human development with competency drive can be sophisticated.
Your universities back home, research institutes and work places except
you to be selective too in thinking, planning and deciding on how your
present courses of studies and degrees can benefit every needy spots in
Egypt.
As you may all know, there is a year of science and technology
between Japan and Egypt throughout the year of 2008, and the eminent
establishment of Egypt-Japan university of science and technology, EJUST in New Borg El Arab city in the nearest future. I look forward for
your involvement in these fronts and much more to take strive as a part of
success endeavour.
EJISST2008 June 8~10
13
Dr. Ahmed B. Khairy
First Undersecretary for Cultural Affairs and
Scientific Missions, Ministry of Higher
Education and State for Scientific Research,
Egypt
Japan and Egypt relations have enjoyed steady development in the
recent years in various fields. Considering the importance of the Decade
for Science and Technology in Egypt, both governments have decided to
make this year "Japan-Egypt Science and Technology Year 2008
(JESTY-08).
JESTY-08 is going to be a platform for increased scientific
cooperation between Egypt and Japan, and is expected to bring the
peoples of Japan and Egypt much closer.
It is crucial for developing and emerging economics, like Egypt to
have people who are skilled at solving complex problems, thus enabling
their nations to create and exploit research, development and innovation.
The education and training of science, engineering, technology and
medical graduates are essential for success.
I hope this International Symposium can bring together scientists from
Egypt and Japan to discuss and share innovative ideas in fields of mutual
interest, and to present the most recent achievements in science and
technology that can improve the quality of life of our citizens and those
of other nations.
I would like to thank WASEDA University for hosting this
Symposium, the Japanese professors for their valuable work and
supervision of Egyptian scholars. Last but not lease, I would like to thank
those who collaborated in preparing these wonderful proceedings which I
hope, bear witness that the goal of this Symposium has been fulfilled.
EJISST2008 June 8~10
14
Dr. Walid Mahmoud Abdelnasser
Ambassador of the Arab Republic of Egypt
to Japan
It is indeed a great pleasure for me to witness the materialization of the
First Egypt Japan Symposium on Science and Technology 2008 (EJSST
2008). This event represents in fact a coronation for many decades of
scientific and technological exchanges between Egypt and Japan,
especially with the number of Egyptian students and researchers in Japan
reaching for the first time in the history of cultural exchange between the
two countries more than 400 students.
It is a fact that as all those students serve as Ambassadors for their
country in Japan by promoting Egypt and shaping its image in the
Japanese mind, they also acquire during their stay, in addition to the
scientific knowledge, a whole set of constructive cultural and social
values which they transmit later to their country. This kind of healthy
interaction represents in a way or another a bridge between two of the
most ancient civilizations, which will help eventually find more common
ground and shared values between our countries, cultures and peoples.
This event is held while the overall bilateral relations between Egypt
and Japan are witnessing an unprecedented degree of maturity especially
in the scientific and technological field. Such maturity is reflected in the
agreement of both Governments of Egypt and Japan in late 2007 to
launch the “Egypt-Japan Year of Science and Technology 2008”
initiative. However, I am confident that a huge potential still remains and
that your contributions will add a new momentum to our excellent
bilateral relations, especially in the scientific field, which has witnessed
the most tangible and tremendous progress over the last years.
EJISST2008 June 8~10
15
Dr. Karam Khalil
Culture Counselor, Culture, Education and
Science Bureau, the Embassy of the Arab
Republic of Egypt in Japan
It is my great pleasure to announce that The First" Egypt-Japan
International Symposium on Science and Technology 2008" organized by
the Culture, Education and Science Bureau of the Embassy of the Arab
Republic of Egypt in Tokyo and hosted by WASEDA University will be
held from 8th to 10th of June 2008 under the year of " Japan-Egypt
Science and Technology Year 2008 " (JESTY-o8).
I hope that this Symposium will bring together Egyptian doctoral
candidate students and Egyptian post doctoral fellow researchers and
their Japanese professors in Japan for exchanging scientific experiences.
This Symposium will be a good platform for increasing scientific
cooperation between Japan and Egypt . It will serve to strengthen the
scientific ties between the two countries to improve scientific
cooperation, and to encourage joint Egyptian-Japanese research activities.
I am happy to announce that more than three hundred papers have
been submitted to EJISST2008 and about two hundred and twenty papers
have been accepted for oral presentation. The Symposium will cover
many fields of science that are of common interest for Egyptian and
Japanese scientists, with special focus on the following thematic research
areas: Nanotechnology, Biotechnology, Information and Communication
Technology, Space Technology, New & Renewable Energy, Health,
Micro electro Mechanical systems (MEMS), Manufacturing & Quality,
Civil and Environmental Engineering, Mechanical Engineering,
Humanities and Social Science (Egyptology, Japanese Studies and
Islamic Studies) .
Lastly , I would like to wish all the participants a constructive and
fruitful symposium.
Best Regards, Thank you.
EJISST2008 June 8~10
16
Dr. Ahmed EL-Salmawy
Cultural Attaché, Culture, Education and
Science Bureau, the Embassy of the Arab
Republic of Egypt in Japan
Science and technology play an exceedingly prominent role in our
world today. They are considered an everlasting source of development
and they ensure the well-being of mankind. It is believed that science and
technology are the heart of the ceaseless ongoing development
worldwide. In fact they have become the main channel and the core
objective of the various sectors of all advanced and developing societies.
In this regard the contribution of Japan in the promotion of science and
the development of innovative technology remains eminent.
Accordingly the scientific cooperation between Egypt and Japan is of
great significance. The First Egypt-Japan International Symposium on
Science and technology (EJISST2008) is an offshoot of a long endeavor
and persistent concern of the Egyptian policy toward enhancing and
effectively employing science and technology in the current reforming
process in Egypt.
EJISST2008 goes beyond founding a common ground for the two
countries to exchange views and implement joint research. It indicates the
firmness of the strong mutual relations and foreshadows a promising
wider fruitful cooperation.
It is noteworthy that both countries, Japan and Egypt, have declared
2008 to be the year of Japan-Egypt Science and Technology (JESTY-08).
Coordinated scientific programs and activities are designed to be carried
out throughout the year. A great deal has been accomplished in this
respect and further accomplishments are expected to be done.
The inauguration of the Egypt-Japan University of Science and
Technology (E-JUST) in Egypt next year will definitely put both
countries on the threshold of a new phase that will enrich and reinforce
the mutual collaboration in all directions.
EJISST2008 June 8~10
PATRONS AND
HONORARY
ADVISORS
17
EJISST2008 June 8~10
PATRONS
His Excellency Dr. Hany Helal
Minister of Higher Education and State for Scientific
Research, Egypt
His Excellency Dr. Walid Abdelnasser
Ambassador of Egypt to Japan
HONORARY ADVISORS
Dr. Ahmed B. Khairy
First Under-Secretary for Cultural Affairs and Missions,
Ministry of Higher Education and State for Scientific
Research, Egypt
Dr. Katsuhiku Shirai
President of WASEDA University
Dr. Tisato Kajiyama
President of Kyushu University
Dr. Yasushi Saito
President of Chiba University
18
EJISST2008 June 8~10
19
ORGANIZATION
COMMITTEE
EJISST2008 June 8~10
20
General Chair:
Chair: Dr. Ahmed B. Khairy
Co-Chair: Dr. Seinosuke Narita (Advisor, Foreign Affairs Office, Senior Researcher,
Information Technology Research Organization)
Secretary General:
Dr. Karam Khalil
(Culture Counselor, Culture, Education and Science Bureau,
the Embassy of the Arab Republic of Egypt in Japan)
Dr. Ahmed Elsalmawy (Culture Attaché, Culture, Education and Science Bureau,
the Embassy of the Arab Republic of Egypt in Japan)
Egyptian Technical Program and Coordination Chairs:
Dr. Ahmed Mounir EL Sayed
(Associate Professor, Kyushu University)
Dr. Shehata Eldabie Abdel Raheem (JSPS Fellow, DrEng., Hokkaido University)
Japanese Technical Program Committee:
Dr. Masao Hattori
Dr. Kousuke Kurokawa
Dr. Seinosuke Narita
Dr. Matsuo Gen
Dr. Towhata Ikuo
Dr. Hiroko Isoda
Dr. Kotera Hidetoshi
Dr. Yoshimura Sakuji
Dr. Susuki Sadami
Dr. Kitamura Toshiharu
Dr. Yamauchi Masayuki
Dr. Iwao Odomari
Dr. Miyashita Mitsumasa
Dr. Hatta Hiroshi
Dr. Toshio Fukuda
Dr. Takaji Kokusho
Dr. Kato Shinsuke
Dr. Tabata Osamu
Dr. Hasegawa So
Dr. Haita Kawakatsu
Dr. Itagaki Yuzo
Secretariat:
Ayman Haggag (Former Head of the Egyptian Students’ Association in Japan-ESAJ )
Egyptian Symposium Organizing Committee:
Dr. Ahmed Mounir EL Sayed
Dr. Shehata Eldabie Abdel Raheem
Ayman Haggag
Moushir M. El- Bishouty
Ahmed Afifi
Saleh Haridy
(Kyushu University)
(Hokkaido University)
(Chiba University)
(Tokushima University)
(Chiba University)
(Kyushu University)
Proceedings Editor:
Moushir M. EL- Bishouty
System Administrators:
Ahmed Afifi
Saleh Haridy
(Former ESAJ Vice Head for Culture Affairs)
EJISST2008 June 8~10
Local Arrangement Head:
Hassan Safi (Head of the Egyptian Students’ Association in Japan- ESAJ)
Egyptian Students’ Association in Japan (ESAJ) Representatives:
Hokkaido Coordinators:
Mabrouk Attia Abd El Daim (ESAJ Vice Head for Financial Affairs)
Ahmed Abderabu
Tohoku Coordinators:
Moataz Mahmoud Mohammed Mekawy
Walid Ibrahim
Kanto Coordinators:
Hassan Safi Hemaid Ahmed (ESAJ Head)
Ayman Haggag (Former ESAJ Head)
Mohamed Abdelrahman Eshaiba
Chubu Coordinators:
Mahmoud Abdalla Hafiz Mostafa
Ahmed Atef
Nagoya Coordinator:
Mahmoud Abd El-Naby
Kinki Coordinators:
Mohamed Mohamed Abdel-Daim (ESAJ Vice Head for Culture Affairs)
Mostafa Thabet (Former ESAJ Vice Head for Financial Affairs)
Chugoku Coordinators:
Tamer Hashem Farag
Mostafa Sarhan (Former ESAJ Head)
Tamer Shehata
Shikoku Coordinators:
Ahmed Kamal Osman
Moushir M. EL- Bishouty (Former ESAJ Vice Head for Culture Affairs)
Kyushu Coordinator:
Saleh Kamal Haridy
21
EJISST2008 June 8~10
22
JOINT
PROJECTS AND
INVITED TALKS
EJISST2008 June 8~10
23
International Cooperation between Egypt and Japan:
- EJUST：A Breakthrough University of Science and Technology Manabu TSUNODA, Dr. Eng.
Senior Advisor (Higher and Technical Education),
Japan International Cooperation Agency (JICA),
2-1-1 Yoyogi, Shibuya-ku, Tokyo, 151-8558, Japan
Tel: 03-5352-5442, Fax: 03-5352-5320, http://www.jica.go.jp
Tsunoda.Manabu@jica.go.jp
1) What is JICA ?
Since its establishment in Aug.1974, JICA has supported socio-economic and human resource
development in order to facilitate the autonomous, sustainable development of developing countries, as
one of Japan’s Official Development Assistance implementing bodies. JICA is now making a new start
to improve its international cooperation work even further with warm-heartedness of human beings.
2) General View of International Cooperation to Egypt
JICA’s major priority programs in Egypt are summarized as follows; ①Realization of sustainable
economic growth and creation of employment, ② Poverty alleviation and improvement of living
standards and quality, and ③Promotion of regional stability. The cooperation to Egypt has a long
history such as the Cairo University Pediatric Hospital (1980-2002), Third Country Training Projects
(more than 20yrs), and A Variety of Projects in the field of Transportation and Environment (more
than10-20yrs). Under the rapidly expanded population of younger generation in Egypt now, support to
higher education is also becoming crucial issue including brain-gain.
3) New Challenging University: EJUST
Egypt and Japan are at present establishing Egypt-Japan University of Science and Technology
(EJUST) at New Borg El-Arab City, Suburbs of Alexandria. Based on a series of discussions and the
site studies by both countries, the following basic concepts of EJUST were confirmed; ①A first class,
leading university, ② Research oriented, graduate focused university, ③ Japanese style approach,
④Unique academic programs, ⑤National university based partnership between Egypt and Japan, and
⑥Role model for Egypt’s 21st century universities. Details on EJUST such as vision/mission, working
plan, uniqueness and structure of education and research are to be explained clearly at the Symposium.
EJUST emphasizes on outstanding human resource development for Egypt. Although there are still
many challenging things to realize the above, once it is established, it could be “breakthrough” of
Science and Technology for Egypt, Arab Countries and Africa.
Heat-Directed Composite Materials: From Concept to Aerospace
Applications
Mohamed S. Aly-Hassan 1,2,3)
1)
2)
Kyoto Institute of Technology, Matsugasaki, Sakyo-ku, Kyoto 606-8585 Japan
Institute of Space and Astronautical Science (ISAS), Japan Aerospace Exploration Agency (JAXA),
3-1-1Yoshinodai, Sagamihara-Shi, Kanagawa-Ken 229-8510, Japan
3)
On Leave of Absence of Faculty of Engineering, Assiut University, Assiut 71516, Egypt
hassan@kit.ac.jp & hassan@isas.jaxa.jp
Recently, increasing demands for smarter and smaller products calls for the development of
multifunctional composites. These materials are used not only as structural materials but also satisfy
the needs for additional functionalities such as thermal, electrical, magnetic, optical, chemical,
biological, etc. In the aerospace applications, the efficient consumption of the limited amount of energy
on the bored is very important for the design requirements (e.g. weight, cost, etc.) and for the
environment. Therefore, maximizing thermal efficiency of the heat transfer applications is one of the
main keys to achieving effective energy utilization, which includes reducing global warming, and
EJISST2008 June 8~10
24
ultimately managing the consumption of energy. In this research, we have been introduced novel
multifunctional composite materials can help with both sides of the equation of consumption of energy
and environment. These composites have additional thermal functionality, called heat-directed
property. This heat-directed capability can conduct the majority of the transferred heat by conduction to
the preferred area or direction of the thermal structure. This distinctive property can be attained by
varying the in-plane thermal conductivity of the composites. The research of these novel composites
has grown to have different composite systems with different micro carbon fibers (PAN-based and
Pitch based), different matrix types (epoxy, phenolic and carbon) and different carbon
nanotubes/nanofibers as fillers in the matrix. These novel composite materials offer sustainable
solutions for the hot structures problems, such as improving the heat transfer efficiency, saving energy
and reducing the thermal stresses, etc.
Conservation Activities of "Egyptian-Japanese Mission for the Mastaba
Idout" (2005-2007)
Hiroshi Suita1, Tadateru Nishiura2, Masaaki Sawada2, Iwataro Oka3, Ahmed S. Shoeib4 and
Adel. I. Akarish5
1
Kansai University , 2Kokushikan University , 3Oka Bokkodo Co., Ltd., 4Cairo University,
5
The National Research Center - Egypt
horus@ipcku.kansai-u.ac.jp
In 2005, “Egyptian-Japanese Mission for the Mastaba Idout” started the conservation and restoration
works of mural painting of burial chamber of Idout, Saqqara. The mastaba of Idout dates back to 2360
B.C. and it was discovered in 1927. The mural painting is located at a subterranean burial chamber,
which was hewn in local hill of Saqqara area. The painted plaster was fragmented and some of them
were peeled off to much degree. Even so, the painting at the burial chamber keeps the original shining
of its colors. Then, we have decided to rescue it by the method of detachment. A feature of our works is
in using non health-hazardous materials as far as possible. The burial chamber we worked in is a close
room located under ground, which allowed little air to circulate through a small door. The synthetic
solvents (Acetone or Toluene), common in this work, were limited to the inevitable usage. Here, we
used Japanese materials, i.e. some kinds of papers and Funori, gloiopeltis glue, made of seaweed. The
aim of the presentation is to focus on the steps and processes of the restoration works, starting from the
fixation of paintings on the walls, the consolidation of the pigments, facing layers, detachment of the
painted plaster layers, backing, and the final fixation of some fragments on their original supports.
Stability Investigation of Mother Rock in a Pharaonic Mastaba (Saqqara)
for its Conservation of Mural Paintings
Tatsuaki Nishigata1, Atsushi Ito1, Tadateru Nishiura2, Ahmed S. Shoeib3, Adel I. Akarish4 and
Hiroshi Suita1
1
Kansai University, 2Kokushikan University, 3Cairo University, 4The National Research Centre
nisigata@ipcku.kansai-u.ac.jp
In the Mastaba Idout, located at the south of the Step Pyramid in Saqqara, the restoration of the mural
paintings of the burial chamber goes under “the Egyptian-Japanese Mission for the Mastaba Idout”.
The mastaba dates back to the beginning of the Sixth Dynasty, Old Kingdom (B.C. 2360). While the
ground part of the mastaba is restored in comparatively good condition, many parts of the beautiful
mural paintings in the burial chamber were seriously damaged, and some parts of the painting were
exfoliated from the mother rock with gypsum plaster. The burial chamber is about 10m depth of the
limestone plateau with the size of 10.4m in length, 4.3m in width, 3.1m in height, and several large
cracks are observed on the mother rock. The condition of weathered rock surface is considerably
worse, and the exfoliation of the rock surface on the ceiling is extremely serious. For restoration of the
mural paintings, we performed investigation to examine the stability of the mother rock and a
reinforcement method for the stabilization of the weathered rock surface. We examined the
stratification of the ground, and measured the displacements of the cracks on the walls and ceiling.
Furthermore, recording the temperature and the humidity inside and outside of the burial chamber, we
EJISST2008 June 8~10
25
are carrying the examination for the ground stabilization method such as rock bolt driving and mortar
injection to the cracks.
Towards academic exchange and cooperation between NWRC and TU
Hattori Kunio and Waleed H. Abou El Hassan
Department of Irrigation & Drainage Water Management,
Tottori University, Tottori, Japan
hattori@muses.tottori-u.ac.jp
Academic Exchange and Cooperation agreement between the National Water Research Center
(NWRC) of Egypt and Tottori University (TU) of Japan was signed in June 2004. The Agreement will
apply for promoting Academic Exchange and Cooperation in the fields of research between the two
institutions. “Strategic Fund for Establishing International Headquarters in Universities” is a new
initiative of the Japanese Ministry of Education. Tottori University (TU) has adopted a project entitled
“International Strategies to Prevent Desertification-Towards a Framework for a Sustainable Society in
Harmony with Nature. NWRC (Egypt), Center for Biological Research of Northwest Mexico
(CIBNOR), Northeast Agricultural University (China) and Xin-Jian Agricultural University (China)
have been selected to promote these strategies. Tottori University delegates led by the President, Prof.
Takayuku Nose, have visited NWRC, Egypt from 2 to 6 of June, 2007. The primary objective of the
visit was to officially open Tottori University’s education and research office at NWRC and sign the
memorandum of agreement on the establishment of the office. However, the group, made important
discussions with officials and researchers of NWRC and had a brief meeting with His Excellency Prof.
Dr. / M. Abu Zied, (Minster of Ministry of Water Resources and Irrigation), the ministry to which
NWRC belongs. The discussions in general focused on how to effectively use the newly opened office
and further strengthen the cooperation between NWRC and TU. Regarding for the cooperation between
NWRC and TU, there is 5 years plan which consists of:

Propose Academic Exchange Program for Promoting Knowledge and Experiences in the Field
of Water Resources Problems and Related Subjects,

Initiate Joint Applied Research Projects for Specific Real Life Field Problems of Mutual
Concerns and Interests for Both Sides,

Develop Joint Training Programs for Appropriate Technology Transfer to Raise the Technical
Skills of Young Researchers, and Increase Awareness of Professionals, and

Develop Consultancy Activities in the Arab and African Regions. Team of Experts from Both
Sides (NWRC and TU) to be Formed According to Needs Driven Activities.
Finally, technical visit of Tottori University research staff to National Water Research Center in Egypt
to point out the technical future strategies for the cooperation was in January 2008.
Seismological Observation in and around the Southern Part of the Gulf
of Suez, Egypt
Nobuo Hurukawa
International Institute of Seismology and Earthquake Engineering (IISEE), Building Research Institute,
Tsukuba, Japan
hurukawa@kenken.go.jp
We have established a seismological network in the southern part of the Gulf of Suez, at the northern
end of the Red Sea. The network consists of 10 satellite stations: five in the southern tip of the Sinai
Peninsula, four on the African continent, and one on Shadwan Island, where a M 6.6 earthquake
occurred in March 1969. The first six stations were installed in August 1994, and the remaining four
were added by June 1996. All data are radio transmitted to a central station in the city of Hurghada. We
found that almost all earthquakes had occurred at the center of the Gulf of Suez, the center of the
northern end of the Red Sea, and the Gulf of Aqaba, where old and new plate boundaries exit between
the African and Arabian plates.
EJISST2008 June 8~10
26
This close relationship between Japan and Egypt had established by the International Training on
Seismology and Earthquake Engineering, which had started in 1960 and held at the IISEE with JICA’s
support. The IISEE accepts total 74 participants from Egypt. The main counterpart in Egypt is the
National Research Institute for Astronomy and Geophysics (NRIAG), from which we accepted many
participants including the present president.
A window to the ancient Earth: Pan-African ophiolites of Proterozoic age
from Southeastern Desert, Egypt
Shoji Arai
Kanazawa University, Japan
ultrasa@kenroku.kanazawa-u.ac.jp
Our Earth has been evolving for 4.6 billion years from its birth, forming and modifying its structure.
We now know that the Earth has been cooled down from the initial fire-ball stage. To understand our
Earth’s dynamics, we should examine various kinds of rocks of various ages from the Earth. Our
understanding of the Earth’s interior (the mantle) is dependent on particular geologic bodies, called
ophiolites, made by particular geologic events such as plate collision. The surface part of the earth
(crust + uppermost mantle) is rigid and divided into more than 10 portions, called plates, which move
independently. They sometimes collide, and one of them may thrust over the other, producing the
ophiolite where we can see deep-seated rocks otherwise inaccessible. The ophiolites are almost young,
formed after 0.5 to 0.6 billion years ago.
The ophiolites exposed in the Southeastern Desert of Egypt (= so-called Pan-African ophiolites) are
particularly old (0.7 to 0.8 billion years old, included in the Proterozoic era of Earth’s history), and we
can see the deep-seated rocks of old Earth there. The mantle section of the Egyptian Proterozoic
ophiolites is composed of the peridotites (called harzburgites) that are very poor in magmatic
components. The Proterozoic peridotites are more depleted on average tha younger peridotites, which
may mean that the former experienced an event producing larger amounts of melts than the latter
(younger ophiolites). This situation is available if ambient temperature was higher in the Proterozoic or
some flux was more available at that time.
Future World Water Assessment through System Dynamics
Toshiharu Kojiri, Junpei Nakatuska and Teng-Sheng Chong
Water Resources Research Center, DPRI, Kyoto University
Gokasho, Uji, Kyoto, Japan, 611-0011
tkojiri@wrcs.dpri.kyoto-u.ac.jp
Freshwater withdrawals by human activities have increased dramatically over the years. Already, at the
beginning of the 21st century, one-sixth of the world’s population was without access to improved
water supply while two-fifths lacked access to improved sanitation. Problems of water resources have
also become much discussed issues in international conferences and multi-national organizations.
This research addresses the problem of growing shortage of water resources by modeling of the socioenvironmental changes. There are two main objects; namely (i) to simulate and predict trends in the
development of human civilization in different continents taking into account the effects of limited
water resources through feedback links between water availability and the human society, and (ii) to
identify the important roles and effects of water resources that have on the growth of the world so as to
aid in the planning of scenarios and policies for sustainable development. A model exploring water
needs of the various continents is developed using System Dynamics. Identification of continents with
acute water shortage and development limitations will also be possible with this model. Besides
focusing on the effects of water on each continent, the model is characterized by its treatment on the
various continents as inter-dependant blocks.
EJISST2008 June 8~10
27
Liver Cancer in Egypt and an Experience of Collaboration in Cancer
Treatment
Hiroshi Maeda, Professor,
Faculty of Pharmaceutical Science, Sojo University, Kumamoto, Japan
hirmaeda@ph.sojo-u.ac.jp
Egypt is one of the country with very high hepatitis virus carrier incidence. The incidence rate may be
as high as 10 times of Japan. Further, incidence of Schistosomiasis mansoni, river water-borne paracyte
infection among population of Nile delta is also amazingly high. Consequently, these two microbial
infections and chronic imflammatory state result in very high incidence of liver cancer in Egypt.
I was asked to collaborate with doctors at International Medical Center in Cairo to provide our
therapeutic strategy against the liver cancer (hepatoma) in Egypt. The Center is one of the top medical
centers in Egypt at World class standard. Hepatoma is, however, one of the most difficult kind of
cancer to cure. Despite several therapeutic options, which are available for the treatment of hepatoma
such as resection, embolization, ethanol infusion, cryo-needle treatment, or high electric frequency
treatment, they can accomplish only very limited success, or many patients are not eligible for these
treatment because they have too large tumor mass (>3cm) to treat, or multinoduler spread are beyond
the point of no return and far from cure. Also, some of these treatments are so painful, or costly, not to
mention of liver transplantation.
Our option is to provide a new strategy using pin-point targeted polymeric drug, SMANCS, which has
been approved in Japan since 1994, that is administered into the tumor feeding artery in the liver (into
the hepatic artery) using lipid contrast agent (Lipidol) as a carrier under X-ray guidance and followed
by evaluation by the CT scan.
By this method we can accomplish a truly pin-pointed drug delivery to tumor, that also warrant highly
intensified tumor imaging in CT scan. The method yielded excellent tumor regression(>90%) without
serious side effects: no hair loss, no blood transfusion due to nor liver/ kidney toxicity was observed.
We extended the treatment also to metastatic liver cancer (from stomach or colon cancer etc.) as well as
cholangio cell carcinoma and cancers of the kidney, etc. I found Egyptian doctors became familiarized
with the procedure of this angiographic procedure for arterial injection, and it was a rewarding
experience.
During this collaborative project I had a few opportunities to give lectures on our new finding on
cancer treatment which utilizes altered vascular pathophysiology in solid tumor. This tumor specific
phenomenon was coined, “enhanced permeability and retention (EPR) effect,” and that can be utilized
for tumor targeted macromolecular drug delivery. The pin-pointed tumor selective targeting of
SMANCS in Lipiodol as described above is an example of EPR-effect. Further, another subject area of
my lectures covered carcinogenesis from chronic infection that involves endogenously generated free
radicals in vivo, which damage DNA and lead to inflammation and cancer. This means, I presented,
preventive measures using free radical scavengers become possible. During the course of this project
many Egyptian doctors and scientists showed great enthusiasm for future collaboration although fund
for this was very limited.
MEMS/MS and Assembly as Key Components and Technology for
Advanced System
Osamu Tabata
Graduate School of Engineering, Kyoto University
tabata@me.kyoto-u.ac.jp
In this presentation, MEMS (Micro Electro Mechanical Systems) and MS (Micro Systems) will be
introduced as a key component to realize advanced systems, and an assembly including packaging will
be raised as a key technology to be addressed as a field to carry out collaborative research and
development between Egypt and Japan. MEMS/MS have been expected to open up new applications in
various fields such as environmental monitoring, chemical analysis, medical diagnostics,
EJISST2008 June 8~10
28
transportation, aerospace, communication and robotics. This is because a concept of MEMS/MS as a
small complex system makes it possible to realize new device/system with higher performance with
lower cost in which various interdisciplinary phenomena interact in a small area across the scale from
millimeter to nanometer. Although many microfabrication technologies have been developed for
MEMS/MS, there are still problems to be addressed as follow; (1) an assembly technology to
incorporate nano scale functional elements into MEMS/MS, (2) a packaging technology to expose
MEMS/MS to real world. Some research examples for these two technologies will be introduced and
future research direction will be discussed.
Nucleosides, nucleotides and nucleic acids: chemistry and biology
Yukio Kitade1,2,3
1
United Graduate School of Drug Discovery and Medicinal Information Sciences,
2
Center for Advanced Drug Research,
3
Department of Biomolecular Science, Faculty of Engineering,
Gifu University, Yanagido, Gifu 501-1193, Japan
ykkitade@gifu-u.ac.jp
RNase L is activated by binding of unusual 2’,5’-linked oligoadenylates (2-5A) and acts as the effecter
enzyme of the 2-5A system, an interferon-induced anti-virus mechanism.1) Recently, RNase L was
identified as a candidate for the hereditary prostate cancer gene HPC1 by a positional cloning approach.
2)
These findings suggest that the activation of RNase L by 2-5A itself might be a novel
chemotherapeutic approach to infectious diseases and cancers. However, natural 2-5A is not suitable as
a chemotherapeutic agent because of its shorter biological half-life due to rapid degradation by
phosphatases and nucleases.
In order to prepare more effective 2-5As and to understand the structure-activity relationship of 2-5As,
a variety of 2-5A analogs with base, sugar and/or linkage modifications were synthesized. On the other
hand, we have recently elucidated the crystal structure of the 2-5A binding ankyrin repeat domain of
human RNase L complexed with 2NH 2
5A.3) On binding 2-5A at the ankyrinN
N
O
O
O
repeat domain, RNase L forms a
NH 2
N
N
HO P O P O P O
O
N
homodimer and removes the ankyrinN
OH OH OH
O
repeat domain from the nuclease
N
NH 2
N
HO
O P O
O
N
domain to become the active form. 4,5)
N
OH
For the purpose of new drug
discovery and
development
for
infectious diseases and cancers, this
paper describes synthesis of facile 2-5A
analogs and the structure-activity
relationship of 2-5As.
HO
O
O P O
OH
2-5A Tetramer
N
NH 2
N
O
HO
N
O
O P O
OH
N
N
N
O
(ppp5'A2'p5'A2'p5'A2'p5'A)
HO
OH
References
1) Player, M.R. et al. (1998) The 2-5A system: modulation of viral and cellular processes through acceleration of RNA
degradation, Pharmacol. Ther., 78, 55-113.
2) Carpten, J., et al. (2002) Germline mutations in the ribonuclease L gene in families showing linkage with HPC1, Nat. Genet.,
30, 181-184.
3) Tanaka, N., et al. (2004) Structural basis for recognition of 2’,5’-linked oligoadenylates by human ribonuclease L, EMBO J.,
23, 3929-3938.
4) Nakanishi, M., et al. (2005) 2-5A induces a conformational change in the ankyrin-repeat domain of RNase L, Proteins, 60,
131-138.
5) Nakanishi, M., et al. (2005) Functional characterization of 2-5A binding determinant of human RNase L. J. Biol. Chem., 280,
41694-41699.
EJISST2008 June 8~10
29
Characterization and Expression of the Insect-Specific
Scorpion Neurotoxins for Pest Control
Mohamed A. Abd El-Rahman1 and Hitoshi Ueda2,3
2
1
Zoology Department, Faculty of Science, Suez Canal University, Ismailia 41522, Egypt. The
3
Graduate School of natural Science and Technology, and Department of Biology, Faculty of Science,
Okayama University, 3-1-1 Tsushima-naka, Okayama 700-8530, Japan.
dr_moh_71@hotmail.com & hueda@cc.okayama-u.ac.jp
Arthropod pests destroy about 25% of the world’s annual crop production, contribute to the loss of
nearly 20% of stored food grains, damage human structures to the cost of millions of dollars, and
transmit an array of human and veterinary pathogens. Considering the cost induced by disease
transmission alone, there has long been strong impetus to develop effective means to control these
pests, and in recent decades because of the increased development of pest resistance to chemical
pesticides, the search for alternative methods has received tremendous attention. Since the evolution of
insecticide resistance, and awareness of environmental and human health impact of some chemical
pesticides, the impetus to produce alternative control methods and new biopesticides has brought to
light a splendid array of compounds originating from insect predators (such as wasps, predacious mites,
cone snails, spiders and scorpions) and pathogens, and from plant defensive compounds. Baculoviruses
are insect-specific viruses that have a narrow host range that qualifies them as benign to the
environment. The narrow host range and restricted specificity ensure that baculoviruses will not harm
nontarget insects. Several scorpion-derived insecticidal toxins have been used to produce recombinant
baculoviruses come from the venom of the scorpions Leiurus quinquestriatus, Buthus eupeus and
Androctonus australis. However the usage of toxin genes to genetically improve baculoviruses
gradually decreases their yield (due to the cytopathic effect of toxins to the insect host cells), several
attempts such as RNAi were used to solve this problem. We had promising results with the
toxicological effects of the crude venom of the Egyptian scorpion Scorpio maurus palmatus on adult
cockroach Periplanita americana. The crude venom inhibited the activity of acetylcholinesterase
(AChE) followed by spastic paralysis and death in the treated insects. Moreover, our results showed
that Scorpio venom has the ability to induce oxidative stress in the treated insect groups. The main
objectives of this study are: (i) cloning and functional characterization of two insect neurotoxins
(Maurocalcine (MCa) and Maurotoxin (MTX) from the Egyptian scorpion Scorpio maurus palmatus;
(2) gaining insight into the toxicological effects of Scorpio toxins and understanding the mode of action
of the expressed toxins through establishing transgenic fly lines (Drosophila melanogaster) which can
express various Scorpio toxin genes MCa and MTX under the control of GAL4-UAS system and heat
shock promoter; (3) improving the baculoviruses as friendly effective environment bioinsecticides by
constructing Autographa californica Nuclear Polyhedrosis Virus (AcMNPV) which can express the
Scorpio toxin genes in insect host cells; and (4) increasing the yield/potency of recombinant
baculoviruses expressing Scorpio toxins MTX & MCa using RNAi technology and selecting the
appropriate promoters to express the toxin genes in insect host cells. The present study will help in the
bioinsecticides field, the gene expression field and the RNAi studies in both Drosophila melanogaster
and Lepidoptera cells.
EJISST2008 June 8~10
30
Tumor Necrosis Factor Receptors on Lymphoma Cells in Enzootic
Bovine Leukosis
KOSUKE OKADA1,2), MANABU IKEDA1,2), SATORU KONNAI3), MISAO ONUMA3),
NAOTAKA ISHIGURO1), and MASANOBU GORYO1,2)
1)
Department of Pathogenic Veterinary Science, The United Graduate School of Veterinary Sciences,
Gifu University, 2)Department of Veterinary Pathology, Faculty of Agriculture, Iwate University, and
3)
Laboratory of Infectious Diseases, Department of Disease Control, Graduate School of Veterinary
Medicine, Hokkaido University,
kosuke@iwate-u.ac.jp
Enzootic bovine leukosis (EBL) is a disease complex of cattle associated with B lymphocytotropic
retrovirus, bovine leukemia virus (BLV). Since it takes a long period for the disease to develop, it is
believed that BLV and host immune responses are closely related. A recent study suggested that TNF is
a key factor in the disease progression. The purpose of this study was to report the expressions of TNF
receptors (TNF-Rs) on tumor cells obtained from cattle with EBL, discuss the relationship among
TNF-Rs expression, phenotype of tumor cells and cellular morphology, and attempt to clarify the
pathogenesis of EBL. Obtained lymphomas in animals with EBL were histopathologically classified
into three types. Immunohistochemically, the lymphomas were classified into three phenotypes. The
results of TNF-Rs expression, all tumor cells in EBL uniformly expressed the TNF-RII, but not TNFRI. TNF-a is a pleiotropic cytokine, which is involved in diverse biological processes including
immune and inflammatory reactions. Furthermore, TNF-a plays a critical role in the elimination of
some infectious agents. On the other hand, its function may promote disease progression. Most biologic
responses of TNF-a, such as the induction and suppression of apoptosis, are considered to be mediated
by two functionally different cell surface receptors, TNF-RI and TNF-RII. In this study, EBL tumor
cells expressed TNF-RII, but not TNF-RI. These results suggest that TNF-RII carries out important
functions in BLV-induced leukemogenesis. We conclude that TNF-Rs play most important role in the
malignant proliferation of B cells and formation of lymphomas in EBL.
Optical Sum Frequency Microscopy for Botanical Analysis
Goro Mizutani, Yoshihiro Miyauchi, and Haruyuki Sano
School of Materials Science, Japan Advanced Institute of Science and Technology, 1-1 Asahidai,
Nomi, Ishikawa 923-1292, Japan,
CREST, Japan Science and Technology Agency, 4-1-8, Honcho, Kawaguchi, Saitama 332-0012, Japan
mizutani@jaist.ac.jp
We demonstrate that non-destructive chemical analysis of starch granules in a water plant Chara
fibrosa can be performed by using optical sum frequency microscopy with visible and infrared
excitation. In measuring the images the luminescence by the visible excitation was subtracted and the
compensation for the excitation intensity distribution. SF light is generated only in the oogonium,
containing a large number of starch granules. The plant cells contain a lot of substances other than
starch, such as cell nuclei, chlorophyll, mitochondria and so on. However, starch has been identified as
the origin of the signals. We have also observed SF intensity images of this oogonium over the whole
spectral range of the C-H stretching vibration (2750~3100cm-1) to obtain its vibrational spectra.
Comparing the SF intensity spectra of the oogonium of Chara fibrosa with those of several saccharides
we conclude that amylopectin is the dominant saccharide component. The selective observation of
asymmetric species in materials is the most useful advantage of SF microscopy, and it cannot be
achieved by other vibrational microscopies such as Raman or IR absorption microscopy. Nonlinear
optical microscopy can be developed as a powerful tool for investigating bioprocesses such as the
photosynthesis associated with starch production in a living plant. In the future this technique can be
applied to many materials from living tissue to semiconductors.
EJISST2008 June 8~10
31
Atomic scale flattening of oxide thin film formed on metals
Hiroshi Nanjo and Fathy M. Bayoumi
RC-CCP, AIST, Japan
hi-nanjo@aist.go.jp
Corroded materials and their systems must be replaced. It takes a large amount of energy to remake the
new material systems and would produce a large amount of CO2. It is known that corrosion resistance
is improved by the surface flatness of metals. We are developing atomically flat oxide surface of
industrial materials by electrochemical and physicochemical methods. The main electrochemical
method is passivation and the high passivation potential in the passive region and the high solution
temperature at 60 ºC are preferable. A cyclic voltammetry and a linear slow increase in the potential are
also good ways. As physical methods, after passivation, UV and IR irradiation and a furnace heat
treatment assists to expand the atomic scale flat region. There is a preferable direction of expanding the
flat terrace. Although the terrace width on a pure iron expanded to 12 nm by passivation at 800 mV vs.
Ag/AgCl and then furnace heating at 50 ºC for 120 min, the terrace length easily reached several ten
nanometers on pure iron, pure titanium, nickel-chromium alloys and type 304 stainless steel. By the
flattening of these metals, the corrosion resistance of the oxide films was improved as about nine times
longer as compared with the case of no treatment. The results were evaluated by the times up to the
film breakdown at an open circuit potential in a 0.1 M hydrogen chloride solution.
Possible applications of solid electrolyte to lithium secondary battery,
sensor and supercapacitor
Koji Yamada
Applied Molecular Chemistry
College of Industrial Technology, Nihon University
Izumi-cho 1-2-1, Narashino, Chiba 275-8575, JAPAN
k5yama@cit.nihon-u.ac.jp
We have been interested in the conduction mechanism of the superionic conductors (solid electrolyte),
due to lithium ion, fluoride ion and proton. Several new superionic conductors have bee reported from
our group. In our fundamental investigations, the processes of the phase transition to their high
temperature superionic phases and the mechanisms of the ionic migration have been studied on the
basis of the structures. In recent years, however, our sustainable society requires the development of
energy devices, such as fuel cell, secondary battery and capacitor. The development of these energy
devices depends strongly on the constituent materials (electrode and electrolyte). Among them the
development of the solid electrolyte having a high ionic conductivity is a key technology for the safety
and compact devises.
In this short summary, two possible applications of the fluoride will be described, an oxygen gas sensor
and a super-capacitor. Superionic fluoride KBiF4 having fluorite structure has been reported to have
conductivity of the order of 10-4 Scm-1 at the ambient temperature. This is due to the fact that the
octahedral site formed by cations is vacant in this fluorite structure. Furthermore, KBiF 4 tends to react
with an ambient oxygen gas to form oxyfluoride. This reactivity together with its high ionic
conductivity leads to a sensing device of oxygen gas sensor. 2nd expected application is a supercapacitor, in which solid electrolyte with a high ionic conductivity forms an electric double layer at the
interface between electrode and electrolyte.
EJISST2008 June 8~10
32
Joint Research Work between:Toyohashi University of Technology and
Assiut University
Electrostatic precipitation, as an important environmental technology
Akira Mizuno
Toyohashi University of Technology
mizuno@eco.tut.ac.jp
For many years, I have been collaborating with Professor M. Abdel-Salam, Dept. Electrical
Engineering, Assiut University, in the field of high voltage, electrostatics and its application in
environment. Prof. M. Abdel-Salam was invited through JSPS fellowship, visiting professor to
Toyohashi University of Technology, and visiting researcher for Industrial Safety Research Institute. I
supervised a PhD student through channel system and attended his phD defense at Assiut. At present, I
am supervising two phD students in Assiut. One will visit this September to Toyohashi through the
Channel system.
High voltage engineering is considered to be related to electrical power generation and transmission,
but not as environmental technology in common. Electrostatic precipitation, one of an important
application of high voltage engineering, has been contributing for cleaning industrial air exhaust,
including large boilers for power generation, furnace in iron industries and cement industries.
Electrostatic precipitation will also be used to control microbes and viruses suspended in air. In
electrostatic precipitation, corona discharge is used. Using wire-to-plate electrode, and with application
of high voltage to a wire, corona discharge takes place around a wire electrode. Air around the wire is
ionized, and ions are emitted towards the plate electrode. Suspended particles are charged by these
ions, and are collected onto the plate electrode. Fundamental mechanisms on starting conditions of
corona discharge, effect of electrode geometries have been jointly studied as listed in the literatures[14].
With corona discharge, radicals are produced. Chemically active species are called radicals, and ionic
ozone and ionic oxygen molecules are typical radicals produced by corona discharges in air. They can
oxidize biological particles. Using E-coli and yeast, mechanism of the lethal effect by corona discharge
has been jointly investigated and published. Electrostatic precipitation can be used to control indoor air
to reduce change of airborne infection. Ozone works to kill bacteria, however, is harmful if exhausted
in indoor air. Fundamental research on ozone production as well as suppression of ozone generation
has been made jointly, and successful results have been obtained, as indicated in literatures[5-8]. At
present, joint research is going to be made on plasma chemical reactions using intense corona discharge
to produce dense radicals, for diesel exhaust cleaning and for biomass processing.
Literatures of the joint work
[1] M. Abdel-Salam, M. Nakano, and A. Mizuno, "Corona-induced pressures, potentials, fields and currents in electrostatic
precipitator configurations," Journal of Physics D: Applied Physics, vol. 40, pp. 1919-1926, 2007.
[2] M. Abdel-Salam, M. Nakano, and A. Mizuno, "Electric fields and corona currents in needle-to-meshed plate gaps," Journal
of Physics D: Applied Physics, vol. 40, pp. 3363-3370, 2007.
[3] M. Abdel-Salam, A. Hashem, A. Yehia, A. Mizuno, A. Turky, and A. Gabr, "Characteristics of corona and silent discharges
as influenced by geometry of the discharge reactor," Journal of Physics D: Applied Physics, vol. 36, pp. 252-260, 2003.
[4] M. Abdel-Salam, A. Mizuno, and K. Shimizu, "Ozone generation as influenced by gas flow in corona reactors," Journal of
Physics D: Applied Physics, vol. 30, pp. 864-870, 1997.
[5] A. Yehia, M. Abdel-Salam, and A. Mizuno, "On assessment of ozone generation in dc coronas," Journal of Physics D:
Applied Physics, vol. 33, pp. 831-835, 2000.
[6] A. Yehia and A. Mizuno, "Calculation of the electrical power dissipated in silent discharge reactors," Journal of Applied
Physics, vol. 98, pp. 1-7, 2005.
[7] A. Yehia, A. Mizuno, and K. Takashima, "On the characteristics of the corona discharge in a wire-duct reactor," Journal of
Physics D: Applied Physics, vol. 33, pp. 2807-2814, 2000.
[8] A. Yehia and A. Mizuno, "Suppression of the ozone generation in the positive and negative dc corona discharges,"
International Journal of Plasma Environmental Science and Technology, vol. 2, pp. 44-49, 2008.
EJISST2008 June 8~10
33
Experience with Plastic Surgery In Ain Shams University and prospects
of cooperation with the Japanese Universities
Amr Mabrouk
Professor of Plastic surgery, Ain Shams University, Egypt
amrmabrouk2000@yahoo.com
This presentation will give an idea of the work done in Ain Shams University Plastic surgery dpartment
one of the oldest departments in Egypt dating since 1959.It will show the type of research going on in
the dpartment and will try to present common problems of intrest that can be the basis of cooperation
with the Japanese Universities.
EJISST2008 June 8~10
ABSTRACTS
34
EJISST2008 June 8~10
35
SESSION 1: Nanotechnology Materials, Process and Products
EJISST-ID 195
Design of low Young’s modulus Ti alloys with high UTS for biomedical
applications
Mohamed Abdel-Hady and Masahiko Morinaga
Nagoya University
Central Metallurgical R&D Institute (CMRDI)
geprell@yahoo.com
The design of novel Ti-based alloys for biomedical applications aims at providing structural materials
which are characterized by a high strength-to-weight ratio, low elastic modulus, low cytotoxicity and a
negligible tendency to provoke allergic reactions. The above mentioned properties are met together in
the type Ti alloys which use the most biocompatible elements, i.e. Ta, Nb and Zr, as alloy
ingredients for stabilizing the bcc phase. This work aimed to design alloys with the low elastic
modulus and high UTS based on the control of phases stability. It is stressed also on the effect of
various alloying elements on the texturing tendency of the alloys after clod rolling. For this study,
across the single phase boundary, two series of alloys, namely A and Z, were designed without and
with 20 mol% Zr-content, respectively. Both Fe and O were added to stabilize phase of the alloys.
Each alloy was tested after 90% cold rolling reduction and after subsequent solution treatment at
1223K for 1.8ks. From the XRD results, the  and the "-martensite phases are suppressed by O
addition to the alloys. It was found that the higher -phase stability led to the formation of the stronger
rolling texture. The UTS of the alloys is readily increased with O- and/or Fe-addition into them. The
UTS after cold rolling reached 1100 and 1350 MPa in A and Z alloys, respectively. Moreover, the
Young’s modulus of the alloys after solution treatment reached as low as 60 and 55 GPa in A and Z
alloys, respectively.
EJISST-ID 219
Characterization of Electrodeposited Hydroxyapatite Coating on
Nanoporous Anodized Titanium
Fathy M. Bayoumi, Madiha A. Shoeib and Hiroshi Nanjo
National Research Institute of Advanced Industrial Science and Technology, RCCCP, Japan
Central Metallurgical Research and Development Institute, Egypt
fathy.bayoumi@aist.go.jp
The surface of pure titanium was treated by electrochemical anodization in 0.50 M H 3PO4 + 0.14 M
NH4F solution. This treatment has generated titania nanotubes. Hydroxy apatite (HAP) was implanted
into the nanotubes using electrochemical deposition. Adsorbed phosphate ions, after the anodization,
facilitated the nucleation of calcium phosphate material inside the nanotubes that resulted in vertical
growth of apatite crystals. This process was followed by post treatment in 1.0 M NaOH at 100 0C for 1
hr. Bond strength of the coating was found to be good and cohesive mode of failure of the coating was
observed after tensile testing. The electrochemical studies in Ringer’s solution revealed that the coated
samples exhibit higher corrosion resistance than the bare metal. The coated samples have nobler open
circuit potential (OCP) values and higher breakdown and protection potentials. The smaller size of the
loops obtained indicates the stability of HAP/Ti interface against corrosion attack and the faster
repassivation tendency of the HAP coatings.
EJISST2008 June 8~10
36
EJISST-ID 233
Electrochemical behavior of anodic film on AZ31 mg alloy in 1M NaOH
solution
S. A. Salman, R. Ichino and M. Okido
Nagoya University
Al-Azhar University
sa.salman@hotmail.com
Magnesium is widely distributed in the earth; it is the eight rich elements in order to both terrestrial and
cosmic plenty. The use of magnesium and magnesium-based alloys in engineering applications has
increased steadily in recent years. However, the materials are of high chemical reactivity and the
inadequate corrosion resistance limited their use. To improve corrosion resistance and the paintadhesion properties of magnesium alloys, further surface treatment is needed to achieve the resistance
necessary for many applications. Anodizing, painting and electroplating are among the current ways to
treat the surface of magnesium and its alloys. Anodizing can produce a relatively thick, dense, hard,
adherent, abrasion-resistant and durable film to improve one or more surface properties, including
chemical, mechanical, electrical or optical properties. In the chemical industry, chromate solution is
typically used to anodize magnesium alloys. However, chromate solutions are hazardous for both the
environment and are difficult to recycle. In this work, the anodic behavior of AZ31 (3% Al, 1% Zn)
magnesium alloy in NaOH solution was investigated. Moreover, the effect of applied potential,
solution temperature and some inorganic additives on the surface morphology and the anti-corrosion
property was examined. Change of the applied potential affect the film properties of coating materials.
Anodizing at high temperature improves the anti-corrosion resistance from anodic polarization
measurement in 17 mM NaCl and 0.1 M Na2SO4 solution at 298 K.
EJISST-ID 283
Ion Dynamics and Giant Dielectric Constant in Pb1-xSnxF2 Solid
Solutions
Mohamad M Ahmad and Koji Yamada
Nihon University
Assiut University
mma7@yahoo.com
Solid solutions of Pb1-xSnxF2 fluoride ion conductors (with x = 0.2, 0.3, 0.5) have been prepared by
mechanochemical milling technique. The as-prepared materials show cubic fluorite-type structure with
small grain size between 25 - 29 nm. The ionic conduction and dielectric properties of these materials
have been investigated by impedance spectroscopy measurements over wide ranges of frequencies and
temperatures. The conductivity spectra, the frequency dependence of the real part of the conductivity,
are analyzed by Almond-West power-law model. The estimated values of the hopping rates and the dc
conductivity of different compositions are thermally activated with almost the same activation energy.
The calculated values of the concentration of mobile ions are almost independent of temperature.
Surprisingly, the investigated materials are found to exhibit giant values of the dielectric constant,
similar to oxide perovskite materials such as CaCu3Ti4O12. The dielectric constant reaches values of >
100000 that is independent of temperatures and frequencies over wide ranges. The giant values of the
dielectric constant are suggested to be due to some internal effects in the materials, rather than from
surface barrier layer capacitance (SBLC) effects at the sample/electrode interface. Interestingly, the
dielectric constant of the current samples is found to increase with decreasing grain size, a behavior
that is quite opposite to what usually observed in giant dielectric oxide materials, where the dielectric
constant is enhanced with substantial growth of the grain size.
EJISST2008 June 8~10
37
EJISST-ID 073
Investigation of Self Assembly Monolayer (SAM) by using Second
Harmonic Microscopy (SHM) and Sum Frequency Microscopy (SFM)
Ahmed El Basaty and Goro Mizutani
Japan Advanced Institute of Science and Technology JAIST
Helwan University
Ahmedbakr@jaist.ac.jp
Many experimental techniques exist for surface studies, but only a few can give quantitative
information about molecular orientation at the interface. Recently, second-harmonic generation (SHG)
and sum frequency generation (SFG) have been developed into very useful surface analytical probes.
They possess all the common advantages of optical techniques, namely, nondestructive, highly
sensitive with good spatial, temporal, and spectral resolution, and applicable to any interfaces
accessible by light. Being second-order nonlinear optical processes, they are forbidden in media with
inversion symmetry, but allowed at interfaces where the inversion symmetry is necessarily broken.
Consequently, they are intrinsically surface specific for interfaces between centrosymmetric media. If
the input or output frequency is tuned over resonances the output is expected to be resonantly
enhanced. Thus, SHG and SFG can also serve as surface spectroscopic tools. While SHG has been used
to probe electronic transitions, IR visible SFG allows studies of surface vibrational resonances. In both
cases, the process is governed by a rank-three second-order nonlinear susceptibility tensor that
characterizes the nonlinear response of the surface. Because of to these advantages of SFG and SHG
we have used them to examine the Self-Assembled Monolayers (SAMs) deposited on a glass substrate ,
and have studied the molecular structure of SAMs after ablations by Femtosecond laser light
irradiation. In this study, we can obtain the detailed information about laser ablation mechanism by
observing SH and SF images of the irradiation area of the SAMs with SH and SF microscopy systems.
EJISST-ID 080
Application of Pulsed Power Technology to Water-Solubilization of
Carbon Nanotubes
Usama Khaled and Junya Suehiro
Kyushu University
South Valley University,
usamakhaled2003@yahoo.com
Carbon nanotubes (CNTs) is one of the very promising nanomaterials in a variety fields. The poor
solubility of CNTs in water or organic solvents limits their use in many potential applications,
especially in biochemical science and engineering. Single walled carbon nanotubes (SWCNTs) were
treated by a microplasma in aqueous solutions with the different pH and conductivities. The
microplasma was achived by generating pulsed streamer discharges, which were triggered by applying
multiple square high voltage pulses to a wire-to-plane or needle-to-plane electrode system immersed in
the CNTs suspension. An advantage of this proposed method is that it is very useful for the preparation
of water –soluble CNTs because it does not need any particular chemical agents or additives for
solubilization. We have recently found that radical formation using microplasma in water and resultant
surface functionalization of carbon nanotubes are considerably influenced by electrical conductivity
and pH of carbon nanotubes suspension. The SWCNTs were highly solubilized in basic solution after
the microplasma treatement compared to the solubility in distilled water. In acid solution, the SWCNTs
were not solubilized and hence aggregated. So, the high pH solution is more effective for the watersolubility of SWCNTs. On the other hand, at lower solution conductivity, a weak streamer discharge
propagated straightly between electrodes. When the conductivity was increased, the streamer discharge
channels were gradually propagated toward more radial direction. As a result, the phenomena of pulsed
streamer discharge and the radical generation intensity were affected by the solution conductivity.
EJISST2008 June 8~10
38
EJISST-ID 158
Novel pH-Sensitive Nanospheres for Colon-Specific Drug Delivery
Abdallah Mahmoud Makhlof and Hirofumi Takeuchi
Gifu Pharmaceutical University
Assiut University
makhlof78@yahoo.com
Novel pH-sensitive nanospheres designed for colon-specific drug delivery were prepared using
polymeric mixtures of poly (lactic-co-glycolic) acid and pH-sensitive methacrylate copolymers.
Budesonide, a topically active corticosteroid, was entrapped as a model drug. The influence of the type
and ratio of pH-sensitive polymer on the physicochemical properties, drug entrapment, and release
profiles of the nanospheres was investigated. The therapeutic efficacy of the prepared nanospheres was
assessed using the trinitrobenzenesulfonic acid-induced colitis rat model, in comparison with
conventional enteric microparticles. Nanospheres prepared with a polymeric blend of PLGA and
Eudragit® S100 (1:1 w/w ratio) showed optimum physicochemical properties and high drug entrapment
(92.7%). Drug release was strongly pH-dependent with about 20 and 28% released at pH 1.2 and 6.8,
respectively, followed by a sustained-release phase from the PLGA matrix when the pH was shifted to
7.4. Animal experiments revealed that oral administration of the new nanosphere system significantly
reduced the clinical activity score, colon/bodyweight ratio, and myeloperoxidase activity when
compared with control animals receiving oral saline. Furthermore, the nanosphere treated animals
showed statistically different results from the microparticle treated group when the data was measured
7 days after the last drug administration. In conclusion, the proposed nanosphere system combined the
properties of pH-sensitivity, controlled release, and particulate targeting that could be useful for colonspecific delivery.
EJISST-ID 176
Preparation of new nanocomposite materials based on layered double
hydroxide
Mohamed Reda Berber and Keiji Minagawa
University of Tokushima
Tanta University
mrberber@sy34.chem.tokushima-u.ac.jp
Layered double hydroxides or anionic clays are deserving an increasing interest due to their numerous
applications and their easy and cheap procedures to prepare them. Their structure consists of layers of
edge-sharing hydroxyl octahedral, in which each magnesium ion being surrounded by six hydroxide
groups while each hydroxide spans three magnesium ions. Replacement of some fraction of the
divalent ions by a trivalent ion of comparable size, results in a net positive charge on the layers
balanced by anions in the interlayer. The nature of the cations in the layers and of the anion in the
interlayer can be changed in a very wide range (giving rise to the so-called hydrotalcite-type materials).
If the layer cations are Mg2+ and Al3+ and the interlayer anion is carbonate the compound thus resulting
is Mg1-xAlx(OH)2 (CO3)x/2·m H2O. These materials provide many interesting applications; anion
exchange properties due to the weak interactions between the interlayer anions and the positively
charged layers, gas adsorption and bio-nanocomposites based on the fact that most of biopolymers
interact strongly with calcium ions. Because of their biocompatibility, these inorganic solids can be
used as host materials to create nanocomposite materials .In the present study, monodisperse particles
of LDH was synthesized by a precipitation method using urea hydrolysis. Here the effect of urea molar
ratio on the LDH properties was studied upon heating.. The structures and properties of the prepared
LDHs have extensively been investigated for advanced materials applications. The synthesis of LDHs
with controlled particle size and uniformity is vital for optimum performance of the functional LDHs.
EJISST2008 June 8~10
39
EJISST-ID 170
Formation of SiC MMC layer on Al alloys by friction stir processing
Essam Rabea Ibrahim Mahmoud and Kenji IKEUCHI
Osaka University
Central Metallurgical Research and Development Institute
essamibrahim2@yahoo.com
Friction stir processing has been applied to the formation of surface composite by uniformly
distributing SiC particles 1.25 µm in size into a surface layer of 5 mm thick Al 1050-H24 sheets. The
SiC particles was filled into a groove cut on the aluminum sheet, covered by 2 mm Al sheet and a
rotating tool was penetrated from the cover sheet so that the probe tip reached depth beyond the groove
bottom. The effects of process parameters (rotation speed and traveling speed) on the homogeneity of
SiC particles in the stirred zone were investigated. The effects of groove size and its position relative to
the tool probe were also investigated. In addition, the effects of applying multiple passes on the stir
zone characteristics were also studied. Applying multiple passes has a great effect on the homogeneity
of the SiC particles. At rotation speeds 3000 - 2000 rpm, the SiC particles clustered in some places in
the stir zone. By decreasing rotation speeds to 1500 - 1000 rpm, the SiC particles were distributed well
in all the stir zone area. On the other hand, the stirring action of FSP can not distributed SiC particles in
the groove 3 X2 mm homogenously. By shifting the groove position towards the advancing side of the
tool probe, the distribution of the SiC particles in the stir zone became better. The defect-free stir zone
with homogenous SiC particles was obtained in sample of rotation speed of 1500 rpm for 1 st pass and
1250 rpm for 2nd and 3rd passes. Microhardness of the surface composite layer was significantly
improved to a level as high as 41 HV for groove 2 x 1.5 mm at 1000 rpm, 46 HV for groove 3 x 1.5
mm at 1500 rpm, and as 55 HV for groove 3 x 1.5 mm at 1250 rpm.
EJISST-ID 204
Iterative Learning Control based nonlinear friction modeling in fast and
precise positioning control
Esam H. Abd-Elhameed and Makoto Iwasaki
Nagoya Institute of Technology
South Valley University
esam@position.elcom.nitech.ac.jp
For many industrial applications, the demand for high-precision servo systems has received great
attention due to the progress of nano-technology in recent years. For the robot arm linear positioning
systems, ball-screw-driven system, in microscopic displacement its friction behavior, which is known
as the stick-slip phenomenon, dominates the resulting performance due to it has high nonlinearity. In
this paper Iterative Learning Control (ILC) is used to model the friction dynamics of the ball-screwdriven system in order to provide high-precision performance of the system in case of microscopic
displacement. The control scheme is composed of two types of control methodology: a 2 Degree of
Freedom (2DOF) mechanism and a feedback learning strategy. At each iteration, the 2DOF provides
stability of the system and keeps its state errors within uniform bounds. The iterative learning rule, on
the other hand, tracks a desired experimental output over a sequence of iterations. The proposed model
results and the experimental results demonstrate that, a sufficient friction model was achieved for
microscopic displacement of the ball-screw-driven system.
EJISST2008 June 8~10
40
EJISST-ID 266
Ion Transport Behavior in Diffusion Layer of New Designed Ion
Exchange-Mosaic Composite Polymer Membrane
A. Mounir EL Sayed and Akira Yamauchi
Kyushu University, Japan
National Institute for Standards, Egypt
mounir_99@yahoo.com
New designed ion exchange-mosaic composite polymer membrane (MM/AEM) was proposed in this
study. The new membrane was made from anionic exchange polymer gel (AEM) that coated onto
mosaic polymer membrane to form AEM/MM polymer composite membrane system. Also, AEM
membrane without mosaic membrane layer was used as reference commercial ion exchange membrane.
The electrochemical properties of new design composite polymer membrane system (MM/AEM) and
non-composite one (AEM) were investigated by chronopotentiometry measurements (CP) and currentvoltage curves (I-V). In the presence of KCl solution, the limiting current density of new designed
composite MM/AEM was higher than that of commerical AEM. In other words, at the same current
density, the transition time of composite AEM was shorter than that of commercial AEM, and also
diffusion layer thickness of composite MM/AEM was smaller than that of commercial AEM. It can be
concluded that the new designed composite anionic exchange polymer membrane provides relatively
good ion transport and other good membrane properties. In addition, the production of this new
designed composite polymer membrane can be used in industry, like electrodialysis, as an alternative
membrane instead of the commercial ion exchange membrane, which suffers from low limiting current
density.
EJISST2008 June 8~10
41
SESSION 2: New and Renewable Energy
-Solar, -Wind, and Bio-Energy
EJISST-ID 056
IMPACTS OF WIND FARMS ON THE POWER SYSTEM QUALITY AND
STABILITY
Omar Noureldeen and Takashi Hiyama
Kumamoto University
South Valley University
omar_noureldeen@yahoo.com
Transient stability assessment is one of the important aspects of modern power system planning, design
and operation. It provides an assessment to the ability of the system to withstand such disturbances.
Nowadays, most of the wind turbines are induction generator wind turbines. The power captured by the
wind turbine converted into electrical power by the induction generator and transmitted to the grid by
the stator winding which is connected directly to the grid. The induction generator requires reactive
power to be supplied from the grid. It is therefore necessary to provide reactive power locally as close
as possible to the demand level. Many new wind power plants are equipped advanced technology
which enables them to provide good service while producing clean power for the grid. The advances in
power electronics have allowed many power system applications to become more flexible and reliable.
Applications such as reactive power compensation, static transfer switches, energy storage, and
variable-speed generations are commonly found in modern wind power plants. This paper investigates
the effect of wind turbine transients on the power system quality and stability. The Matlab software and
Simulink toolbox are used to model transient events of wind turbine on power systems stability.
EJISST-ID 142
A Methodology for Designing and Evaluating Biomass Utilization
Networks
Nasser Mohamed Abdelwahab Ayoub and NakaYuji
Tokyo Institute of Technology, Japan
Helwan University, Egypt
n_ayoub@yahoo.com
This paper presents a methodology for designing and evaluating Biomass Utilization Networks, BUN,
in local areas. Therefore, the proposed methodology assumes the great importance of establishing the
BUN superstructure for the area under study, which relates the biomass resources to their products,
available processes and possible future processes of utilization. Using the developed network
superstructure, the quantitative data of the local biomass resources, the bioproducts demands, the
redundant resources and processes, due to low amount, low demand, or technical problems, are
excluded. Then two types of network structures were set upped, the first is the reference models that
show the current situation with its possibilities for improvements and the second type is future network
structures that can be established excluding, or partly including, the current utilization strategy. The
resulted network structures are used as a blue print for different scenarios of integrated biomass
utilization systems that can be evaluated in comparison to the reference scenario. Optimizing the
different scenarios allows us to define the bottlenecks in the biomass utilization system that limits its
total throughput. Solving the optimization problem of the selected network structure in the local level
needs high rank of details where each resource’s supply chain includes wide range of Unit Processes,
UPs, that meet domestic circumstances e.g. logistics, production facilities, and so on. The GA was used
to solve this optimization problem as a powerful tool in solving such combinatorial problems
EJISST2008 June 8~10
42
considering three optimization criterions, e.g. costs, emissions, energy consumption to congregate the
different economical and environmental burdens of the established BUN.
EJISST-ID 245
DESIGN OF RENEWABLE ENERGY SYSTEM IN AN EGYPTIAN SITE
Abou-Hashema M. El-Sayed
Kyushu University, Japan
El-Minia University, Egypt
dr_mostafa555@yahoo.com
Energy source problems are becoming more serious world-wide. Development of alternative energy
source for the post-petroleum age is being promoted in all countries triggered by the first oil crisis in
1973 and the subsequent oil problems accompanied by individual societal and economic backgrounds.
This is the same in Egypt, and development of alternative energy sources has been accelerated
especially since the second oil crisis in 1978. Several new alternative energy sources are nearing
practical application of these sources, fuel cells, photovoltaic power, wind power and storage batteries
are classified as distributed power sources. Therefore, this paper aims to use renewable energy (Solar
energy) source to overcome the difference between the required power today and that after 10 years in
Elminia site. Elminia site is located at the south of Egypt. Its latitude is 28.08 N. From the peak loads
at Elminia substation recorded during the last ten years, and by analyzing these loads, it is found that
the excess factor may be taken as 2. The photovoltaic power system, PVPS, has been designed to be
interconnected with utility grid, UG, and supply these excess loads through the UG. It is taken into
consideration that the power produced from the designed PVPS must be satisfied to overcome the new
loads. Different three selected types of solar cells have been examined to represent the generation
device of the designed PVPS. Then the suitable solar cells type has been determined. Finally the
construction and reliability of the designed PVPS have been investigated.
EJISST-ID 014
Laser Induced Magnesium Oxide Reduction for Renewable Energy Cycle
with Solar Power
T. Yabe, S. Uchida, M.S. Mohamed, C. Baasandash, Y. Sato, Y. Mori, and H. Sato
Tokyo Institute of Technology, Japan
Minia University, Egypt
Mohamed.s.aa@mech.titech.ac.jp
In order to restore renewable energy as chemical energy, we succeeded in producing magnesium from
MgO without reducing agent using high power cw laser. Magnesium in turn can react with water to
produce hydrogen, heat and MgO, thus natural recourses can be stored as chemical energy in
magnesium. As a preliminary analysis, a focused CO2 laser irradiated MgO target in atmospheric
condition, and the presence of Mg lines, MgO lines and O + lines was confirmed by spectral analysis of
ablated vapor from MgO target. Subsequently, the focused CO2 laser irradiated MgO target in vacuum,
high temperature is exerted in tiny spot thus Mg production in equilibrium is achievable. Ar or He gas
flows across the ablated vapor to cool and direct it to the copper collector. The resultant Mg vapor is
deposited on Cu plate and analyzed by EPMA (electron probe micro analysis); the results showed
points of more than 30% mol fraction of Mg deposited, with an average of 8 mol%. So far bulk
analysis results showed that 6 mol% of Mg is obtained as solid deposit, which can be translated to
energy conversion efficiency of 0.35 mg/kJ. These experiments showed that our scheme can be used
for magnesium production with higher efficiency and large throughput.
EJISST2008 June 8~10
43
EJISST-ID 076
Electrochemical deposition of indium sulfide thin films for solar cell
application
Ashraf Abdel Haleem and M. Ichimura
Nagoya Institute of Technology
Fayoum uinversity
ashraf_ahaleem@yahoo.com
Indium sulfide thin films have been successfully deposited on indium-tin-oxide (ITO)-coated glass
from an aqueous solution containing Na2S2O3 and In2 (SO4) 3 by electrochemical deposition using a
periodic 2-step voltage. The films have been annealed in nitrogen atmosphere for one hour at different
temperatures. Then, the as-grown and annealed films were characterized structurally, optically and
electrically. The photosensitivity of the films was observed by means of photoelectrochemical
measurements, which confirmed that the indium sulfide showed n-type conduction. Moreover, a novel
heterostructure solar cell, possessing indium sulfide as a buffer layer and tin sulfide as an absorber, was
fabricated and characterized.
EJISST-ID 131
Development of a DMFC Employing a Novel Electrode Structure
Mohammad Abdelkareem and Nobuyoshi Nakagawa
Gunma university
El Minia University
abdelkareem3031@yahoo.com
Direct methanol fuel cells (DMFCs) are expected as power units with high energy densities that are
suitable for mobile electric devices. The amount of energy released by a given volume of methanol is
orders of magnitude larger than even highly compressed hydrogen. However, at the current level of the
technology, the energy density of the DMFCs is still far from that expected due to large permeation of
methanol through the proton-exchange electrolyte membrane, which is known as the methanol
crossover (MCO). Other problems include the management of carbon dioxide evolved at the anode.
The authors have demonstrated that a passive DMFC with a novel electrode structure, a porous carbon
plate (PCP) was placed on the anode surface, significantly reduced the methanol transport from the
methanol reservoir to the anode surface. The effect of placing the PCP under closed circuit conditions
on the performance, methanol and water transport across the membrane electrode assembly (MEA) was
investigated. Moreover the effect of the pore structure and thickness of the PCP, as well as the CO 2 gas
barrier layer, thickness, pressure, and the discharging route whether through the PCP or not on the
methanol transport and the performance of a passive DMFC were also investigated. Results show that
using of PCP significantly reduced the methanol crossover and increase both of the fuel efficiency and
the power density of the DMFC. The CO2 gas layer formed between the MEA and the PCP was
essential for significantly limiting the methanol transport to the anode surface where the gaseous
methanol diluted in the CO2 gas. The main factors for controlling the methanol transport were the
barrier of the gas layer with CO2, and the properties of the PCP. At high current densities, CO 2 bubbles
were evolved through the PCP, and different resistances to the methanol transport were observed
depending on the PCP pore structure and thickness. The discharging of CO2 bubbles across the PCP
enhanced methanol transport in case of large pore diameter PCP.
EJISST2008 June 8~10
44
EJISST-ID 243
Intelligent Wind Turbine
Ahmed Mohamed Galal and Toshiaki Kanemoto
Kyushu Institute of Technology
Mansoura University
ahmadgalal2007@yahoo.com
Growing energy demand and environmental global warming have re-evoked human interest in
Renewable Energy. Wind energy is a clean and home grown resource of electric power generation,
which has been positively/effectively utilized to cope with the warming global environment. Although
propeller wind turbines are so effective, but the conventional turbines may have some weak points such
as that the large-sized wind rotor does not operate at the weak wind, the power generation of the smallsized wind rotor is low, and it is necessary to be equipped with the brake and/or the pitch control
mechanisms, to suppress the abnormal rotation and the generated overload at the stronger wind, and to
keep good quality of the electric power. To overcome the above weak points, the authors have invented
the superior wind turbine generator, which was called the “Intelligent Wind Turbine Generator” by the
authors, as the rotational speeds of the tandem wind rotors are adjusted pretty well in cooperation with
the two armatures of the generator in response to the wind speed.This unit is composed of the tandem
wind rotors and the double rotational armature type generator without the conventional stator. The
large-sized front wind rotor and the small-sized rear wind rotor drive respectively the inner and the
outer armatures of the generator, in keeping the rotational torque counter-balanced. Such operating
conditions enable to make the output higher than the conventional turbine and to keep the output
constant in the rated operation mode without using the brake and/or the pitch control mechanisms. This
report discusses the wonderful advantages in the generating mode and prepares preliminarily
optimization to the rotor profiles, accompanying with the experimental results.
EJISST2008 June 8~10
45
SESSION 3: Manufacturing and Quality - Fabrication of
Electronic Components
EJISST-ID 183
Application of the repulsive type magnetic bearing technology based on
digital control implementation for manufacturing a micro mass
measurement system
Alaa A. Hussien, Sotoshi Yamada, and Masayoshi Iwahara
Kanazawa University, Japan
El-Minya University, Egypt
alaahazem1@yahoo.com
The repulsive-type magnetic bearing technology is becoming attractive for many applications in recent
years, specially, for the high precision instruments. The most important feature of magnetic bearing in
general is the contact-free operation. In addition, the repulsive type specially offers many other
advantages such as, small number of electromagnets and a simplified scheme are needed for control, it
also have a soft and constant stiffness to the passive control axis. So, this type of bearing is right suited
for many applications. In this research, the repulsive type magnetic bearing based on digital control
implementation is employed to manufacture a balance system which can measure micro masses. The
mass measurement devices which have high measuring sensitivity to detect the minute change of a
sample mass are necessary for performing kind of material characterization analysis. In some
applications, that change sometimes reaches the order of micro-grams or even nano-grams. So, high
sensitivity measuring instruments are needed The proposed system consists of an axial shaft and a
balance beam, the shaft is levitated along the radial direction by the repulsive forces of the magnetic
bearing section and along the axial direction by a controlled electromagnet. The beam is kept at an
equilibrium horizontal position. The principle operation depends on transferring the mass value to the
current of a controlled actuator. The function of the system as a mass measuring device is confirmed by
measuring some samples, and evaluating the system measurement characteristics such as sensitivity,
control current hysteresis and linearity.
EJISST-ID 206
Development of low noise RF front–end for ultra-wideband (UWB)
systems on 0.18um CMOS Technology
Ahmed I. A. GALAL, R. K. Pokharel, H. Kanaya and K. Yoshida
Kyushu University
Minia University
Galal@yossvr3.ed.kyushu-u.ac.jp
In recent years ultra-wideband (UWB) radio technology has attracted enormous attention because it can
transmit the data over a wide frequency bands for short ranges with low power and even higher data
rate compared to narrow-band systems. Numerous methods have been proposed for ultra-wideband
(UWB) communication systems. One of the most critical components in an UWB radio system is the
front-end low-noise amplifier (LNA) because it needs to provide low noise figure and high gain over a
very broad frequency range. There are two major challenges for the UWB LNA design. The first one is
to achieve the optimal noise matching and gain matching simultaneously. The second one is to
implement the matching network over a wide frequency band. In this research, a 3.1-10.2GHz UWB
LNA has been designed and fabricated on TSMC 0.18um CMOS 1P6M process. The simulated results
using Advanced Design System (Agilent, ADS) demonstrate that the proposed LNA yields a high gain
and a low noise figure over a wide bandwidth. The proposed architecture consists of cascode amplifier
EJISST2008 June 8~10
46
for high gain over wideband, an input matching, inter-stage network and a inductive peaking to expand
the frequency range and resistor shunt feedback. This technique can provide good impedance matching
and improve gain flatness at the expense of gain. The proposed LNA delivers 19.7dB gain, noise figure
3.1dB over a range from 3.1 to 10.2 GHz. and dissipates 25mW of power.
EJISST-ID 210
Noise Reduction of Randomly Switched DC-DC Converters by Digital
Controller
Gamal M. Dousoky, Masahito Shoyama and Tamotsu Ninomiya
Kyushu University, Japan
Minia University, Egypt
{gamal, shoyama, ninomiya }@ees.kyushu-u.ac.jp
DC-DC converters are important in portable electronic devices such as cellular phones , laptop
computers, and electric vehicles, which are supplied with power from a DC power source such as
batteries, photovoltaic cells, or fuel cells. Such electronic devices often contain several sub-circuits
with each sub-circuit requiring a unique voltage level different from that supplied by the source
(sometimes higher or lower than the source voltage, and possibly even negative voltage). Switching
power converters have been reported to generate common-mode and differential-mode conduction
noise in addition to radiated noise. They may cause serious problems by generating such switching
noise. Although switching converters produces significant amounts of switching noise, they are also
required to operate inside electromagnetic interference (EMI) sensitive applications. This research aims
to reduce the switching noise produced by DC-DC Converters. Traditional tools for EMI suppression
are related to the use of filters and shielding techniques. But these tools are bulky and require expensive
passive components, which makes them unsuitable for space-limited and price-sensitive portable
devices. Alternative, random-switching technique eliminates the need for EMI filters by spreading the
switching-mode power supply (SMPS) noise over frequency range. This is typically achieved by
randomly varying the switching frequency of the SMPS. Random-switching control is effective for
suppressing the peak level of switching-noise spectrum. A field-programmable gate array (FPGA) has
made substantial improvements in price and performance throughout the past few years. Although
FPGA implementation is now widespread in a range of military and defense, signal processing
applications such as sonar, radar, and image processing. It is much flexible than analog control,
becoming lower cost, and applicable for power supply applications. The implementation of SMPS has
been accomplished by using FPGA digital control. Breadboard has been built-up for testing the effect
of random-switching control in DC-DC Converters. It includes DC-DC power switching circuit, power
switch driver, analog to digital conversion circuit, FPGA advanced digital controller, and interface
between the FPGA digital controller and the driver. Low noise digitally controlled converter has been
developed.
EJISST2008 June 8~10
47
SESSION 4: Biotechnology - Agriculture - Food (1)
EJISST-ID 165
Indirect 15N isotope techniques for estimating rice N uptake from poultry
manure and sewage sludge
Adel Ghoneim and Hideto Ueno
Ehime University, Japan
Rice Research & Training Center, Egypt
adel.ghoneim@yahoo.com
Continuous use of chemical fertilizers for long time may accelerate the depletion of organic matter. It
has been shown that crop N recovery from organic inputs such as poultry manure and sewage sludge or
manures is often less than 20%. However, has been widely accepted that organic inputs play a
significant role in the long-term build up of soil organic matter and associated soil stabilization. The
use of poultry manure and domestic sewage sludge in agriculture is being considered as one of the
methods for recycling of these wastes in an environmental beneficial manner. An investigation was
undertaken to investigate the influence of added poultry manure and sewage sludge on N dynamics and
rice N uptake. The experiment was set up as a completely randomized block design with five
replications and the following treatments: control (C), chemical fertilization (CF), sewage sludge (SS)
and poultry manure (PM). Nitrogen fertilizer was applied at rate of 8.0 g m -2 (14N) applied three splits
at different rice growth stage. The application rate of SS and PM was 160 and 200g FW m-2,
respectively, added at full just before transplanting. Sewage sludge and poultry manure traced with 2.0
% atom 15NH4Cl labeled only @ 0.30 g N m-2. The nitrogen uptake was positively influenced by
different treatments and the highest N uptake was obtained with chemical fertilizer. At maturity, the N
uptake of PM was significantly higher than SS. The relative efficiency was varied with organic
materials. No significant difference was observed between PM and SS in the N remaining in the soil
and N lost from soil-plant system.
EJISST-ID 202
Towards Integrated Water Management for Sustainable Agricultural
Development in North Sinai, Egypt
W. H. Abou El Hassan, Y. Kitamura and K. Shimizu
Tottori University, Japan
National Water Research Center, Egypt
wwaleed975@hotmail.com
Egypt faces the strategic challenge of improving the productivity and sustainability of water use, rather
than increasing water supply. Also, Egypt have a per capita availability of renewable fresh water
resources of 891 m3 per annum and this is projected to decline to 650 m3 per annum by 2017. The new
updated for horizontal expansion plan of agricultural land, to be completed by 2017, aims at adding
1.43 million ha to the existing agricultural area. The climate of the investigated study area is belonging
to the arid zone, characterized by a short dry period. The source of water for project area is the River
Nile (Damietta branch) mixed with drainage water (1:1 ratio) from El Serw and Hadous drains in the
Nile Delta. However, the information on the effect of water and land management for sustainable
development in North Sinai Development Project is scanty and not well documented. Also, evaluation
of water productivity and water use efficiencies is scanty. This paper presents to illustrate the potential
of water and land management for saving water to sustain the development of North Sinai. Key words:
Integrated irrigation and drainage, sustainable agriculture development, Sinai Peninsula.
EJISST2008 June 8~10
48
EJISST-ID 012
Application of Congo red agar to detect Streptococcus dysgalactiae
subsp. dysgalactiae isolated from diseased fish
Mohamed Abdelsalam and Terutoyo Yoshida
University of Miyazaki
University in Cairo
ng2704u@student.miyazaki-u.ac.jp
The strong clinical similarity between Lancefield group C Streptococcus dysgalactiae subsp.
dysgalactiae (GCSD) and Lactococcus garvieae, characterized by the development of necrotic lesions
in the caudal peduncle, has prevented these 2 strains from being identified. Furthermore, a mixed
infection of GCSD with L. garvieae has been observed in fish farms. Consequently, rapid and accurate
diagnosis of diseased fish in fish farms is urgently required to diagnose the GCSD. Congo red binding
and bacterial adhesions to hydrocarbon tests are commonly used as markers of cell hydrophobicity in
pathogens. The GCSD strains indicated hydrophobic cell surface with significant Congo red binding
ability than L. garvieae strains. A presumptive identification and isolation of GCSD obtained from
diseased fish was performed using Todd-Hewitt agar containing 30 μg/ml of Congo red dye (TH-CR).
The TH-CR agar was also applied to detect and presumptively identify GCSD obtained from artificially
or naturally infected fish. The results revealed orange GCSD colonies on TH-CR agar, distinguishing
them from the L. garvieae colonies. Therefore, the TH-CR agar can be used as one of tools to detect
and identify GCSD obtained from infected fish.
EJISST2008 June 8~10
49
EJISST-ID 044
Characterization of Cytochrome P450 CYP1A in Ungulates
Wageh Sobhy AbdElrahem, Mayumi Ishizuka, Kentaro Sakamoto and Shoichi Fujita
Hokkaido University
Zagazig University
wagehdarwish@yahoo.ca
[Introduction] Cytochrome P450 (CYP) 1A have been extensively studied in laboratory animals and
humans but the expression of CYP1A in meat producing animals either domestic such as cattle and
camel or exotic like deer and horse has received little attention. CYP1A profile in the liver of these
animals will facilitate an appreciation of potential species differences in biotransformation, and thereby
this will support the evaluation of the risk associated with the presence of drugs, procarcinogens and
other contaminant residues like insecticides in edible tissues. The aim of this study is to characterize
CYP1A in the following Ungulates, cattle, deer, horse, camel and rat as reference species. [Materials
and Methods]We collected three female liver samples from each species with an age range of one to
two years and from 9 weeks old wistar rats as control. Liver microsomes were prepared from liver of
cattle, deer and horses to detect CYP1A expression using Western blotting analyses, and to measure
CYP1A-dependent ethoxyresorufin O-deethylase (EROD) activity, methoxyresorufin O-demethylase
(MROD) activity and Ames Mutagenicity Assay. [Result and Discussion] We detected the CYP1A-like
proteins in the liver microsomes from various ungulates using anti-rat CYP1A1 antibody. In addition,
we analyzed kinetic parameters of EROD in liver microsomes of Ungulates. Especially, the equine
microsomes had the highest EROD activities among the examined species; horse liver showed 6-fold
higher than that of rats at the substrate concentration of 20 μM, followed by cattle and deer
respectively. The same findings were obtained using both of MROD activity and Ames mutagenicity
assay.
EJISST-ID 046
Nanotechnology meets plant biotechnology: Carbon Nanotubes deliver
DNA and elicit biochemical responses in plants
Maged Fouad, Noritada Kaji, Manabu Tokeshi and Yoshinobu Baba
Nagoya University
Zagazig University
fmaget@mail.apchem.nagoya-u.ac.jp
In this contribution, we show that cup-stacked carbon nanotubes (CNT) with cellulase immobilized on
their sidewalls and tips can serve as an efficient DNA delivery system for plant cells in cell suspension
culture. A GFP-plasmid strongly adsorbed to CSCNT leading to its cytoplasmic translocation.
Transfection efficiency was recorded to be 6% using 750ng of plasmid for 10 5 Arabidopsis thaliana
cells. This approach circumvents the removal of the entire cell wall in case of protoplast
transformation and may provide a powerful tool for highly efficient gene transfer into a variety of plant
cells, especially hard-to-transfect cells. CNT were found to act as abiotic elicitors when added to
Arabidopsis thaliana callus culture. Qualitative and quantitative estimation of total glucosinolates was
achieved using microchip capillary electrophoresis/MALDI-TOF-MS and showed about 5.5 folds
increase in case of cultures containing CNT compared to normal cultures. Seven different
glucosinolates were identified in normal cultures, while ten different glucosinolates were identified in
cultures containing CNT. CNT were found to participate in the dehrogenative polymerization of
coniferyl alcohol (an important biochemical reaction in lignin biosynthesis) by acting as an electron
acceptor in the polymerization process. CNT were easily detected in the structure of tracheids formed
naturally in Arabidopsis cell suspension culture. Results were confirmed via confocal and atomic force
microscopy. These studies suggest CNT to be a valuable biotechnology tool that can serve as a new and
promising agent for plant DNA transfection and cell biology studies and elicit the plant defense
network leading to production of valuable phytochemicals.
EJISST2008 June 8~10
50
EJISST-ID 161
Reconstruction of Iron-Oxidation Enzyme System from the Rusticyanin,
c-Type Cytochrome and aa3-Type Cytochrome c Oxidase of SulfurGrown Acidithiobacillus ferrooxidans ATCC 23270
Taher M. Taha, Tadayoshi Kanao, Fumiaki Takeuchi, and Tsuyoshi Sugio
Okayama University
Al-Azhar University
tahery1@yahoo.com.
Bioleaching is an outstanding biotechnological method for extracting precious metals from their
refractory sulfide ores. This process is promoted by special microbial consortia including iron- and/or
sulfur-oxidizing microorganisms. The key reaction in this process is the oxidation of non soluble
sulfides to soluble sulfates. Understanding of the mechanism of sulfur oxidation by iron and sulfur
oxidizers will strongly help in optimizing the bioleaching process to get the highest efficiency. In this
study we tried to study one of the most argumentative points in sulfur oxidation of A. ferrooxidans
namely, an involvement of iron oxidation system in sulfur oxidation. A. ferrooxidans ATCC 23270
cells grown in sulfur medium without ferric iron for successive generations showed high ferrous iron
oxidizing activity comparable to that of the iron-grown cells. This activity is localized in plasma
membranes and it was found to be dependent on protein and ferrous iron concentrations. The inhibitors
of aa3 type cytochrome c oxidase strongly inhibited this activity. Cytochrome c, aa3 cytochrome
oxidase and blue copper protein rusticyanin, the components of iron oxidation enzyme system, have
been isolated in partially purified forms from sulfur-grown cells. The ferrous iron oxidation activities
of these components separately or in combinations were tested. The presence of the three components
was absolutely needed for the reconstruction of iron oxidation activity. The reconstruction of iron
oxidation enzyme system from proteinous components of sulfur-grown cell strongly supports the
proposal of the involvement of iron oxidation system in sulfur oxidation.
EJISST-ID 055
First Characterization and Emergence of SHV-60 in Raw Milk of a
Healthy Cow in Japan
Ahmed Moustafa Hammad and Tadashi Shimamoto
Hiroshima University
Minufyia University
ahmedhmmd@yahoo.com
During screening of raw milk samples of healthy animals in the farm of Hirohima University for
presence of antibiotic resistant bacteria, one isolate of Klebsiella pneumoniae found to be resistant to
aztroneme, cefoperazone, ampicillin, streptomycin and naldixic acid but susceptible to cefotaxime,
cefoxitin, cefotetan, ceftazidime, kanamycin and ciprofloxacin. It was found to produce ß-lactamase
with isoelectric point 7.6. In order to characterize the ß-lactamase synthesized by this strain, blaSHV ,
blaTEM , blaOXY , blaOXA , blaCTXM and blaCMY genes tried to be amplified using PCR. A positive
amplicon was obtained only for SHV ß-lactamase gene. Southern hybridization using the whole blaSHV
gene as a probe showed that the gene is located on the chromosome. The combination of the two
mutations by which SHV-60 differs from SHV-1, namely, L35Q and A187T, has not been described
before. It must be expected that this strain will spread further among food-producing animals and
thereby constitute a reservoir of this resistant strain and resistance gene that can transfer to and cause
treatment problems for humans. This study confirms the hypothesis that novel ESBL producers, which
have the potential to cause treatment problems in humans may initially emerge from food-producing
animals and reports for the first time of such an emergence in Japan. Surveys are needed to assess
whether this is a unique situation on a single farm or if ESBL-mediated resistance may be emerging
within animal populations in Japan.
EJISST2008 June 8~10
51
EJISST-ID 075
Taxonomic study of the subgenus Lasioglossum s. str. of the genus
Lasioglossum (Hymenoptera, Halictidae) in Japan
Mohamed A. Shebl, Ryuki Murao and Osamu Tadauchi
Kyushu University, Japan
Suez Canal University, Egypt
mohamedshebl2002@hotmail.com
The subgenus Lasioglossum belongs to the genus Lasioglossum in the family Halictidae (Insecta,
Hymenoptera). This subgenus is known to occur in the Holarctic Region, and about 162 species are
recorded. The bees of this subgenus visit flowering plants for the purpose of collecting pollen and
nectar for their progeny. Therefore, they may be useful when utilize for pollinator of crops and fruit
trees. In spite of its importance for pollination, Lasioglossum s. str. has not been satisfactorily studied
in Japan, 15 species of this subgenus have been fragmentarily described and recorded. However, they
are often difficult to identify due to the lack of adequate taxonomic information for each species and a
useful identification system such as key to species. The purpose of our study is aimed to revise the
Japanese Lasioglossum s. str. as the following topics: 1) clarify the Japanese fauna; 2) redescribe
previously described species from Japan; 3) construct a useful identification system; 4) accumulate
biological information such as flight and flower records for each species, 5) accumulate data of DNA
barcoding for each species. In our presentation, we report a result of the first topic.
EJISST-ID 087
Anti-babesial ellagic acid rhamnosides from the bark of Elaeocarpus
parvifolius
Ahmed Elkhateeb and Hideyuki Matsuura
Hokkaido University
National Research Center in Egypt
elkhateb@chem.agr.hokudai.ac.jp
The infection of dogs with the parasite Babesia gibsoni is a worldwide problem, and in recent years the
geographic range of the infection has spread. B. gibsoni proliferates within erythrocytes by lysing the
cells, which results in the induction of anemia in infected animals. The drug diminazene aceturate
(Ganaseg) has been shown to be effective against B. gibsoni infection but causes side effects such as
weakness, irritability, paralysis, non-responsiveness to stimuli and fatal central nervous system
hemorrhage. Because of this, production of the drug was recently stopped, and an alternative
chemotherapeutic agent with few side effects is urgently needed for the treatment of B. gibsoni
infection. It is possible that the investigation of plant extracts may provide an affordable treatment.
Bioassay-guided investigation of the bark of Elaeocarpus parvifolius led to the isolation of three new
ellagic acid derivatives, 4-O-methylellagic acid 3'-α-rhamnoside (2), 4-O-methylellagic acid 3'-(3"-Oacetyl)- α-rhamnoside (3), and 4-O-methylellagic acid 3'-(4"-O-acetyl)- α-rhamnoside (4) in addition to
one known ellagic acid derivative, 4-O-methylellagic acid 3'-(2",3"-di-O-acetyl)- α-rhamnoside (1).
Their structures were elucidated on the basis of 1H NMR, 13C NMR, HMQC, HMBC and MS spectral
data. Compounds 1-4 were evaluated for their growth-inhibitory effect on Babesia gibsoni in vitro.
Compounds 2 and 4 showed very weak activity, while compounds 1 and 3 showed moderate activity,
with IC50 values of 28.5 and 52.1 µg/ml, respectively.
EJISST2008 June 8~10
52
EJISST-ID 097
Identification and expression analysis of a novel interleukin 8(IL-8)in
carp(Cyprinus carpio, L)
Nevien Kamel Mohamed and Miki Nakao
Kyushu University
Mansoura University
neevy2003@yahoo.com
Interleukin 8 (IL-8) is a CXC-type cytokine with a chemotactic activity mainly on neutrophil and play a
key role in promoting inflammation. In teleosts, some CXC chemokines have been cloned and
characterized as members of CXC-chemokines lineage. In the present study a novel interleukin 8 (IL8)-like chemokine designated as caIL-8 has been found in the expressed sequence tags (EST) of carp
gills, and identified as the closest ortholog of mammalian IL-8. The caIL-8 transcript consists of a 66
bp 5-UTR, a 297 bp open reading frame (ORF) encoding 99 amino acids, and a 374 bp 3-UTR.
Multiple sequence alignment drawn by using ClustalW revealed a distribution of the four-cysteine
residues conserved among caIL-8 and other CXC chemokines. Phylogenetic tree constructed by
neighbor-joining method showed that caIL-8 clustered with mammalian IL-8 orthologs, whereas the
previously reported teleosts IL-8 clusters together in a distinct clade. Expression pattern of caIL-8 was
analyzed by RT-PCR from various organs and compared with those of the previously reported carp
CXCa and CXCb. In which carp CXCa and CXCb were expressed in most organs of nonstimulated
fish, whilst tissue distribution of caIL-8 mRNA was limited in gills, head kidney, spleen and peripheral
blood leukocytes.
EJISST-ID 104
Functional characterization of the promoter of a juvenile hormoneregulated gene, Vitellogenin-2, from the cockroach Periplaneta
americana
Azza Elgendy and Makio Takeda
Kobe University
Cairo University
azzajapan1@yahoo.com
The Periplaneta americana vitellogenin (Vg) genes are subject to sex- tissue- and stage-specific
regulation, and are expressed exclusively in the adult female fat body cells under the hormonal control.
Juvenile hormone (JH) and 20-hydroxyecdysone (20E) are involved in transcriptional regulation and
inhibition of Vg genes in P. americana, respectively. To elucidate the regulatory mechanisms of Vg2
gene, the upstream region of 1841 bp was cloned and characterized. To better understand the role of
different response elements, 10 different constructs of the Vg2 promoter sequence were used with the
luciferase assay system in Sf9 cells to screen for the minimal sequence motif required for Vg2
activation and suppression by the JHIII and 20E, respectively. We found that a 204 bp fragment is
sufficient to support JHIII for Vg2 induction, but not 20E for inhibition. Furthermore, we investigated
the luciferase activity under this minimum promoter length using different doses of JHIII at different
time intervals. Our results demonstrate that Vg2 is indirectly induced or inhibited by the JHIII and 20E.
Also we identified a 14 bp direct repeat (DR2) with 2 spacer overlapped with 10 bp inverted repeats
(IR). Work is in progress to identify these hormone response elements using mutagenesis techniques,
luciferase assay and EMSA protocols.
EJISST2008 June 8~10
53
EJISST-ID 126
Studies on lactic acid production from xylan by novel strains of marine
lactic acid bacteria, Halolactibacillus miurensis
Amira M. Hamdan and Kenji Sonomoto
Kyushu University
Alexandria University
Amira_ahmed1314@yahoo.com
Novel strains of marine lactic acid bacteria, Halolactibacillus miurensis M23-1~5, isolated from
marine organisms (living sponge, decaying alga and raw shellfish), in Oura Beach, Kanagawa
Prefecture, Japan, were used for direct lactic acid production from xylan. In screening for the most
promising strain of H. miurensis, different sources of xylan [β-1,4 xylan (birchwood and oat-spelt) and
β-1,3 xylan (green seaweed)] were tested. M23-4 strain showed the highest yield of lactic acid from
different sources of xylan and was selected to continue further work. In optimizing the conditions of
the pre-culture medium for M23-4 strain, different carbon and nitrogen sources were tested. It was
found that, in presence of sorbitol (10 g/l) and both fish extract and polypeptone (5 g/l for each) in the
pre-culture medium, highly activated the xylan-degrading activity of M23-4 strain for main cultures.
Also in a survey for choosing the best buffer solution for the enzyme assay, Glycine-NaOH buffer (pH
8.5) was selected for further work. Crude extracellular enzyme preparations showed high stability upon
storage for longer periods at both -30ºC and -80ºC. Extracellular and intracellular enzyme preparations
from M23-4 cultures grown on both xylose and birchwood xylan contained primarily exo-1,4-βxylanase and β-xylosidase, respectively. In a survey for the best medium for lactic acid production
from xylan, different media and conditions were tested. The results showed that shaked flasks of
GYPFK media (pH 8.5) containing 10 g/l xylan, gave the highest yield of lactic acid than static ones or
other types of media. For testing the optimum inoculum size for high cell density jar fermentation, 120% cell inoculum were tested after concentrating 9 liters culture medium 45 times using hollow-fiber
microfiltration module. The results showed that 10% cell inoculum succeeded in producing 3.41 g/l
lactic acid directly from 10 g/l xylan after 24-h incubation at 37ºC and initial pH 8.5.
EJISST-ID 127
Studies on lactic acid production from polysaccharides by novel lactic
acid bacteria
Abd El-Rahman, M.A, Keisuke Shibata, Takeshi Zendo and Kenji Sonomoto
Kyushu University, Japan
Al-Azhar University, Egypt
Mohamedali_micro@yahoo.com
A study was conducted to isolate, screen and identify bacteria for the production of lactic acid from
cellulosic biomass as it represents an abundant natural renewable carbon resource and the production of
value-added products from such renewable feedstock is a present need and perhaps economically and
environmentally feasible process. Nine natural sources; Takana pickle, wood, cuttle fish pickle, radish
pickle, dry radish, cucumber pickle, fish and soil were evaluated for the isolation of lactic acid bacteria
(LAB). A total of 164 isolates were obtained by using MRS and CMG broth media supplemented with
2% glucose, 0.5% cellobiose or 0.5% carboxymethyl cellulose (CMC) in addition to use of 2.0%
glucose plus 10% NaCl in the case of isolation from Takana pickle. By sequential screening for
catalase activity and lactate production, 63 strains were determined to be LAB. Furthermore, 412
isolates from stocked strains in Laboratory of Microbial Technology, Faculty of Agriculture, Kyushu
University were grown on MRS- and CMG-cellobiose agar medium supplemented with 0.5% CaCO3,
out of which 157 strains were determined to be cellobiose-utilizing lactate producers by showing a
zone of clearance in cellobiose agar plates. A separate hydrolysis and fermentation (SHF) bioprocess
scheme was used for lactate production with CMC, where enzymatic pretreatment was carried out by
cellulase (Onozuka-R10) for 20 min at 50oC. A quantitative screening test for L-lactic acid production
EJISST2008 June 8~10
54
for a total of 220 strains was carried out by MRS and CMG broth media supplied with 0.5% cellobiose
or enzymatically pretreated CMC. Many strains produced a relatively high L-lactate by utilization of
supplied sugars, with the highest yield up to 3.36 g/L after 72 h of fermentation which corresponded to
82 % conversion, on the base of consumed cellobiose, whereas the maximum lactate obtained from
CMC-hydrolyzate was reached up to 1.07 g/L, which corresponded to 76% conversion of the utilized
sugar. Based on the highest L-lactate production, 25 strains were considered as the most potent lactate
producers and selected for screening of the desirable traits such as homofermentative ability,
production of single isomeric form of lactic acid, etc.
EJISST-ID 138
Effects of anti-oxidative nutrients on unloading-mediated expression of
atrogenes
Dalia Hemdan and Takashi Nikawa
Tokushima University
Menshawi Hospital, Ministry of Health, Egypt
mbmd74@yahoo.com
Skeletal muscles are vulnerable to marked atrophy under microgravity. This phenomenon is due to the
transcriptional alteration of skeletal muscle cells to weightlessness. Muscle atrophy results primarily
from accelerated protein degradation and is associated with increased expression of two musclespecific ubiquitin ligases (E3s): atrogin-1 and muscle ring finger 1 (MuRF1). Previous researches
reported that unloading, including spaceflight as well as tail suspension, stimulated ubiquitination of
various proteins, including myosin heavy chain (MHC), and accumulation of MHC degradation
fragments in atrophied rat gastrocnemius muscle. Researchers also found that unloading induced
expression of several ubiquitin ligases, such as atrogin-1, MuRF-1 and Cbl-b which are rate-limiting
enzymes in muscle protein degradation. In this study, we investigate whether “anti-oxidative nutrients",
such as epicatechin (EC), epigallocatechin (EGC), epicatechin gallate (ECG) and epigallocatechin
gallate (EGCG) can prevent expression such as atrogenes induced by 3D-clinorotation. Our results
suggest that catechins may prevent unloading-induced muscle atrophy through suppressing atrogin-1
and MuRF-1 expression.
EJISST-ID 140
Monitoring Changes in the Arthropods Biodiversity in Satoyama area
with special reference to Carabid Beetles as Bioindicators
Wael Mahmoud El-Sayed and Nakamura Koji
Kanazawa University
Cairo University
wael_elsayed88@yahoo.com
Changes in the Biodiversity in Satoyama area in Kanazawa were detected. Mainly, there were four
different sampling areas representing different habitat types in Satoyama. These areas were Kakuma,
Kitadan, Zontan and Grassland areas around Kanazawa University, Ishikawa Prefecture. Changes in
the biodiversity of Arthropod, including carabids, were detected and monitored monthly from May till
November. Anthropogenic, restoration activities and other factors affecting habitat characteristics were
periodically monitored and their effects on Arthropods biodiversity were analyzed. Carabids were
selected for the study for their high sensitivity to land restoration and chronological habitat change.
These carabids were used as bioindicators for each habitat. The biodiversity was analyzed and
determined using different diversity indices including Shannon, Simpson, Berger-Parker, McIntosh,
Camargo indices with trends in applying new indices. The similarity among the different communities
was estimated using two different modules. The number of species was estimated using specific species
index and it was clear that the number of species increased among years in some habitats while the total
EJISST2008 June 8~10
55
abundance together with the total number of species decreased. The Evenness was also estimated using
the proper index of Evenness.
EJISST-ID 141
Performance of the Cotton Leaf Worm Spodoptera littoralis (Boisd.)
(Lepidoptera: Noctuidae) fed Cotton Plant Leaves Gossypium barbadens
(Malvaceae) grown under Ambient 350 ppm and Enriched 700 ppm CO2
Regimes
Shahenda Abu El-Ela Ali and Nakamura Koji
Kanazawa University
Cairo University
shosho_ali76@yahoo.com
Cotton leaf worm is a serious pest attacking many crop and economically important plants. One of the
most economically fiber plant is the Gossypium barbadens. Cotton leaf worm, Spodoptera littoralis,
was raised in the laboratory and fed on both cotton leaves grown under two different carbon dioxide
regimes, one is the ambient concentration (350ppm) and the other was raised on enriched carbon
dioxide concentration (700ppm). Plant shoot analysis including the nitrogen, phenolics, carbohydrates,
soluble and insoluble sugars, non-reducing sugars, proteins, carbon: nitrogen ratios were performed.
Life tables, The Approximate digestibility, Amount of ingested food and other indices were estimated.
The main destructive stages were confined mainly to the late instar larvae which show a voracious
feeding pattern and drastic damage to the plant shoot. It was clear that larvae fed cotton plant leaves
grown under enriched carbon dioxide regime consumed much leaves than those fed leaves grown under
ambient carbon dioxide regime. Moreover, leaves of cotton plant grown under enriched carbon dioxide
regimes have comparatively low nutritional values than those grown under ambient carbon dioxide
regimes.
EJISST-ID 166
Dynamics of carbon and nitrogen derived from 13C and 15N dual-labeled
compost in continuously application in a vegetables soil
Azza Ebid and Hideto UENO
Ehime University, Japan
Ministry of Justice, Egypt
azzaebid2002@yahoo.com
As well known, application of organic fertilizers decrease the need for inorganic fertilizers and mitigate
environmental degradation. Experiment was conducted to investigate the nitrogen and carbon dynamics
in upland soil for radish, komatsuna, and chingensai cultivation by using 13C (1.256 atom%) and 15N
(1.098 atom%) dual-labeled maize residue compost (MRC). The vegetables were grown over 3
consecutive growing seasons over 4 months; compost was applied at the rate of 24 g kg -1 soil. Nitrogen
uptake and yield of vegetables were significantly higher with the recommended inorganic N treatment.
The values of the N uptake derived by fertilizer application to the plant exhibited significant
differences among different vegetables. Nitrogen recovered by komatsuna and chingensai from MRC
was (7.3, 6.6%), (2.7, 1.8%), and (2.3, 1.7%) in first, second, and third crop, respectively. Radish,
komatsuna, and chingensai recovered significant amounts of C from MRC in the first and second crops,
with negligible C recovery in the third crop. The initial loss of fertilizer C in soil at first crop indicates
that the microbial decomposition decoupled substantial amounts of 13C/15N labeled compounds early in
plant development, thus giving the microorganisms a pre-emptive competitive advantage in the
acquisition of easily available 13C/15N labeled substrates. It is concluded that a combination of compost
and inorganic N did not supply sufficient plant-available N to increase vegetables yields or N uptake
over those of fertilizer alone. The data suggested that higher productivity of vegetables might be
achieved after the accumulation of a certain amount of residual compost-N.
EJISST2008 June 8~10
56
EJISST-ID 162
Utilization of biotechnology for improving abiotic stresses in cereals
Alhosein Hamada Abd-El-Azeem and Takatoshi Tanisaka
Kyoto University
Assiut University
Alhosein1@yahoo.com
Introduction: Stress conditions, such as drought, heat and salinity, are major problems that adversely
affect cereal crop production. Improvement of stress tolerance through classical breeding approaches is
a historically particularly difficult task, and progress is shown to be relatively slow in most cases. The
time has come when new strategies based on molecular-biological technologies are available for
improving stress tolerance. Objectives: Identify primary, fundamental causes of stress-induced yield
and growth reduction. Evaluate different genotypes of cereals under certain stress conditions.
Determine genetic factors for stress tolerance (gene identification). Identify stress impact on gene
expression. Improve DNA marker system for marker-assisted selection. Steps of study: Quantifying
effects of morphological and physiological characters that influence yield and quality under stress
conditions. Different DNA markers will be applied to screen effective genotypes for stress tolerance.
QTL mapping will be done to identify chromosomal regions responsible for stress tolerance. QTL
cloning will be done for the previous item to investigate gene function for stress tolerance. Outcome of
the study: The outcome of our study will help the plant breeder to select tolerant genotypes using
accurate selection at the molecular level, and to develop stress tolerant germplasm.
EJISST-ID 052
Fermented milk product prepared with probiotic bacteria affects the
onset of obesity in rats
Essam M. Hamad, Ibrahim I. Abd El-Gawad and Katsumi Imaizumi
Kyushu University
Cairo University
essam_hamad@yahoo.com
While many previous studies have reported the health-promoting effects of fermented milk and
probiotics, their effect on the growth of adipose tissue remains unexplored. To investigate the effects of
fermented milk products produced by Lactobacillus gasseri SBT2055 on adiposity, we fed four-weekold male Sprague-Dawely rats a diet containing skim milk (control diet) or skim milk fermented by
Lactobacillus gasseri SBT2055 (LGSP diet) for 4 weeks. Their body weight gain, adipose tissue
weight, adipocyte size distribution profile, blood and hepatic lipids, and serum leptin, glucose and
adiponectin levels were determined. The average of adipocyte size in mesenteric white adipose tissue
was significantly reduced (P=0.004). Also, the rats fed the LGSP diet displayed greater numbers of
small adipocytes from mesenteric and retroperitoneal adipose tissues than did those on the skim milk
diet. While there was not any different in the adiponectin concentrations between the groups, serum
leptin concentrations were decreased to 32% (P=0.031) in the LGSP diet group compared with the
control group. Concentrations of serum glucose and lipids, and liver lipids, except for the liver
triacylglycerol level, were similar in the two groups. Although the underlying mechanisms remain to be
unraveled, our results suggest a novel role of fermented milk in the regulation of adipose tissue growth.
EJISST2008 June 8~10
57
SESSION 5: Biotechnology - Medicine (1)
EJISST-ID 062
Branchial Sodium- Potassium ATPase enzyme activity of Mitochondrionrich cells In Mozambique tilapia in response to Osmotic changes
Sameh Magdeldin Mohamed and Yamamoto tadashi
Niigata University, Japan
Suez Canal University, Egypt
samehmagd@yahoo.com
Changes in cellular activities of mitochondrion -rich cells (MRCs) and its Sodium- Potassium
Adinosintriphosphatase (Na+/K+-ATPase) enzyme mRNA transcripts were examined in Oreochromis
mossambicus (O. mossambicus) adapted to freshwater (FW) and 180% seawater (SW) environments
for 2 week . Plasma osmolality showed excellent adaptability of both groups. Na+/K+-ATPase mRNA
gene expression was significantly higher (P<0.01) in 180% SW adapted group than fish adapted in FW.
Immunocytochemical staining of MRCs using antiserum specific to α-subunit of Na+/K+-ATPase
enzyme revealed remarkable significant elevation (P<0.05) in the highly stained MRCs in fish adapted
to 180% SW. In contrast, moderately stained cells were significantly higher (P<0.05) in FW group,
while low affinity-stained MRCs were non-significant between both groups. Numerical quantification
of immunoreactive MRCs (irMRCs) showed the existence of 69.2% of high reactive cells in 180% SW
adapted fish while it was only 30.8% in FW adapted. Moderately reactive cells were 18% in SW
adapted fish and 41.2% in FW adapted group while low reactive cells were 12.8 % and 28% in 180%
SW and FW groups, respectively. Our findings indicating that excellent salinity tolerance of O.
mossambicus is attributed to the Na+/K+-ATPase activity of MRCs especially in hypertonic
environment.
EJISST-ID 214
Monocarboxylate Transporter 1 (MCT1) in the Gastrointestinal Tract of
Ruminants
Doaa Kirat and Seiyu Kato
Rakuno Gakuen University, Japan
Zagazig University, Egypt
doaakirat@hotmail.com
Despite the significance of short chain fatty acids (SCFA) in maintaining the ruminant physiology, the
cellular mechanism(s) for their absorption from the gastrointestinal epithelia are still incompletely
known. Therefore, the present work illustrates the possible involvement of monocarboxylate
transporter 1 (MCT1) in the SCFA transport across the ruminant gastrointestinal tract. To achieve this
goal, our studies were designated to fulfill the following three main aspects: studying the expression,
distribution and cellular localization of MCT1 along the entire length of the gastrointestinal tract in
various ruminants species using RT-PCR, Western blotting and immunohistochemistry; exploring the
physiological role of MCT1 in the ruminant gastrointestinal tract using both in vivo and in vitro
functional studies on the rumen and cecum epithelium; and studying the co-localization of MCT1 and
its chaperone ancillary protein, CD147, using double immunofluorescence confocal laser-scanning
microscopy. The overall outcomes of this work are: firstly, describing the expression, regional
distribution and precise cellular localization of MCT1 along the entire gastrointestinal tract of
ruminants; secondly, providing evidence, for the first time in ruminants, that MCT1 has a direct role in
the transepithelial transport and efflux of the SCFA and their metabolites toward the blood side;
thirdly, confirming significant differences in the level of MCT1 protein of the stomach between milkfed calf and adult cattle, which strongly support the up-regulation of MCT1 by the substrate and age-
EJISST2008 June 8~10
58
related metabolic changes; and lastly, verifying the fact that CD147 is required for the proper
localization of MCT1 in the ruminant gastrointestinal epithelial cells.
EJISST-ID 238
Pathological study on the scuticociliatosis affecting natural and farmed
Bastard Halibut (Paralichthys olivacus)in Tottori prefecture, Japan
EMAN M. MOUSTAFA, A. SHIMADA, and T. MORITA
Tottori University, Japan
Kafr El-Sheikh University, Egypt
emantarek2002@yahoo.com, emantottori2010@yahoo.com
There are reports of occurrence of the scuticociliatosis in both natural and farmed fishes throughout the
world including Japan, Korea and Spain. Precise mechanism of the infection, disease process and
detailed pathology are yet to be resolved. In addition, there are conflicts in the identification of the
ciliates. This work was carried out to study the effect of scuticociliatosis on natural and farmed Bastard
Halibut (Paralichthys olivacus ) in Tottori prefecture, Japan. So, we collected 10 samples from Tottori
(the fish culture center of Tottori Prefecture) suffering from cutaneous ulcers, darkened skin,
swimming behaviour alterations, and abdominal distention to identify the causative histophagus ciliate.
In addition to about 150 samples for the experimental infection to study pathogenecity, route of
infection, target organs, disease process, presence of the secondary infection, ways of rapid
dissemination in the body, cause of death. Histopathological results revealed severe encephalitis and
meningitis , degeneration of the muscle fibers, accumulation of histophagus ciliates inside the blood
vessels, hyperplasia of the branchial epithelium, and vascular and perivascular inflammation. In some
cases, parasites were surrounded by abundant monocytic and lymphocytic infiltrate. It is concluded that
the route of infection is either the nasal route leading to initial infection of olfactory rosette and then
migration along the olfactory nerve to the brain, or through the penetration of the periorbital skin and
the cause of death is accumulation of ciliates in the branchial blood vessels leading to obstruction effect
on lamellar capillary network hindering uptake of oxygen ending by asphyxia.
EJISST-ID 013
In Vitro Expression of Natriuretic Peptides in Cardiomyocytes
Differentiated from Monkey Embryonic Stem Cells
Essam Mohamed Abdelalim and Ikuo Tooyama
Shiga University of Medical Science
Suez Canal University
essam_abdelalim@yahoo.com
Embryonic stem cells (ES cells) are the most attractive source of cell replacement therapy. ES cells
allow the replacement of nonfunctional cardiomyocytes and scar tissue with new fully functional
contracting cells, and improve cardiac function. Physiological functions of cardiomyocytes
differentiated from ES cells are important for transplantation therapy and several questions need to be
addressed before clinical application of ES cell-derived cardiomyocytes. It is of importance to clarify
their abilities to function as normal cardiomyocytes, which is not investigated in detail. One of the
crucial functions of cardiomyocytes is a production of atrial and brain natriuretic peptides (ANP, BNP),
which have important endocrine, autocrine and paracrine functions. Therefore, in the present study, we
differentiated monkey ES cells into functional cardiomyocytes expressing ANP and BNP in vitro.
Spontaneously contracting cells appeared as clusters of beating cells in the differentiated embryoid
body (EB) outgrowth at differentiation day 20 to 26, and then the obtained beating cells were
propagated in vitro. The contracting cells showed nodal-like action potentials (pacemaker cells), and
expression of cardiac markers. ANP and BNP expressions were detected by RT-PCR and
immunocytochemistry. Interestingly, ANP and BNP expressions were detected as immunoreactive
granules in the perinuclear area and these signals appeared to co-localize with trans-Golgi network.
EJISST2008 June 8~10
59
These findings suggest that monkey ES cells were able to differentiate into cardiomyocytes with
functional characteristics, which can be enriched in vitro and therefore can be used as a useful model
for developing ES cell-based therapy and for basic study of early cardiogenesis.
EJISST-ID 035
Ki-67, p53 and Epidermal Growth Factor Receptor expression in early
laryngeal cancer treated with radiotherapy
Wael A. Ahmed and Kenji Suzuki
Fujita Health University
Sohag University
waelmonaem@hotmail.com
Purpose: To evaluate the prognostic significance of immunohistochemical expression of Ki-67, p53
and Epidermal Growth Factor Receptor (EGFR) in predicting the response of early glottic anterior
commissure (AC) carcinoma to radiotherapy and analysis the impact of thyroid cartilage invasion by
tumor cells at the AC as anatomical cause of irradiation failure. Methods: - Twenty-four patients with
laryngeal glottic cancer involving the AC were treated with radiotherapy as the primary line of
treatment. The mean age of the patients was 64.92 years. Six patients had T1a, 12 had T1b and 6 had
T2. Radiotherapy was done with the same technique for all patients using linear accelerator device with
the beam energy of 4-MV photons. Biopsies were taken before the treatment started.
Immunohistochemical staining was performed using Avidine-Biotine-Peroxidase technique with
antibodies to Ki-67, p53 and EGFR. Recurrent or persistent cases after radiotherapy had either open or
endoscopic CO2 laser salvage therapy. Surgical specimens from patients who had open salvage surgery
were subjected to histopathological examination for presence of cartilage invasion. Results: - We
identified an overexpression of KI-67 as a predictive marker of radio sensitivity with the results
showing significant difference between radiosensitive and radioresistent tumors. Thyroid cartilage
invasion by the tumor cells was confirmed only in 21.43% of patients who had open salvage surgery.
Conclusions: - Ki-67 could be a predictive marker of radio sensitivity. Thyroid cartilage invasion by
tumor cells was not the main cause of local failure after radiotherapy.
EJISST-ID 040
Evidence of linkage on chromosomes 4q28 and 7q in a genome-wide
linkage scan for comitant strabismus susceptibility loci among
Japanese families
Sherin Elsayed Shaaban and Toshihiko Matsuo
Okayama University
Mansoura University
sherinshaaban@yahoo.com
Purpose: Aiming at identifying chromosomal susceptibility loci for comitant strabismus, we performed
a genome wide linkage analysis study among 57 Japanese families. Methods: 57 families were
recruited, in which two or more family members have been diagnosed as either comitant esotropia or
exotropia. Genomic DNA was isolated from peripheral blood, 400 microsatellite markers with ~10 cM
(centimorgans) resolution were amplified by PCR (polymerase chain reaction). Samples were analyzed
by ABI PRISM 310 Genetic Analyzer. Using GENEHUNTER software, NPL (non parametric linkage)
scores, P-values and HLOD (heterogeneity logarithm of the odds) scores were calculated. We further
stratified the families according to phenotype (esotropia or exotropia) to investigate whether the results
would remain consistent among both groups. Results: Regions with the highest peaks suggestive of
linkage were found at D1S413 (HLOD=2.1, NPL=2.19), D1S207 (HLOD=2.07, NPL= 1.96), D7S484
(HLOD=2.32, NPL=2.32), D7S486 (HLOD=2.32, NPL=2.7), D8S284 (HLOD=2.83, NPL=2.28),
D11S1320 (HLOD=1.97, NPL=1.87) and D20S195 (HLOD=2.01, NPL=2.39). Significant evidence of
linkage was found at D4S1575 (HLOD=3.62, NPL=2.68) and at 107.28cM on chromosome 7p between
EJISST2008 June 8~10
60
markers D7S657 and D7S515 (HLOD= 4.4, NPL=2.45). After stratifying the families to an esotropia
and exotropia subgroup, suggestive evidence of linkage was obtained in the esotropia subgroup at
6q27, 8q24.21, 10q22.2, 15q22.2 and 17p13.1. Only one locus at 14q21.3 reached suggestive evidence
of linkage in the exotropia subgroup. Conclusion: Our results suggest several susceptibility loci for
comitant strabismus. The inconsistency of results among the subgroups might suggest a different
genetic base between esotropia and exotropia.
EJISST-ID 048
Molecular Characterization of PVL-Positive Staphylococcus aureus
isolated from Egypt
Shymaa Enany and Tatsuo Yamamoto
Niigata University, Japan
Suez Canal University, Egypt
Shymaa21@yahoo.com
Staphylococcus aureus is a common pathogen worldwide. It expresses a variety of exoproteins,
including Panton Valentine leukocidin (PVL). The data about molecular characteristics of PVL+
methicillin sensitive and methicillin resistant S. aureus (MSSA and MRSA) has been widely reported,
but it is still limited for Egypt. The aim of this study was to screen the presence of PVL+ S. aureus
strains in Egypt and to analyze their molecular characteristics. S. aureus strains were isolated during
2007. The presence of PVL, enterotoxins, exfoliative toxins, adhesions, hemolysins, and mecA genes
were analyzed by PCR. MLST, agr, SCCmec, and spa types were also detected. MIC testing was done
by agar dilution method. The prevalence of MRSA was 80.8%, and PVL+ was 19.23%. From PVL+
strains 20% was MSSA and 80% was MRSA. One MSSA was agr (II), the new spa (824), and the new
ST assigned as ST (1009). PVL+ MRSA was susceptible to non beta lactames, has low MIC values of
oxacillin and carried mecA gene. One of MRSA was agr (IV), spa (312), the new ST assigned as ST
(1010), and the new SCCmec type and 2 MRSA isolates had new spa types. PVL+ MRSA isolated for
the first time in Egypt. One strain resembled ST30 clone, globally spread worldwide, but this time
possessing SCCmec V. Also the new SCCmec type was detected, thus further analysis are still required
in Egypt.
EJISST-ID 082
Deep brain simulation for Parkinson disease
Mohamed Ali, Youichi Saitoh, Koichi Hosomi Haruhiko Kishima, Satoru Oshino, Masayuki
Hirata and Toshiki Yoshimine
Osaka University
Mansura University
drmoali@hotmail.com
BACKGROUND: Deep brain stimulation for the treatment of Parkinson disease has markedly
increased in popularity over the past 15 years. METHODS: We review our results in 16 patients
Parkinson disease with who were operated upon on Osaka university hospital focusing on applications
and efficacy of DBS. A multidisciplinary team consisting of a movement disorders neurologist, a
functional neurosurgeon, and a neuropsychologist optimally selects patients for Deep brain stimulation.
Patients must be significantly disabled despite optimal medical therapy and be cognitively healthy
without significant psychiatric disorders. Deep brain stimulation was done using Leksell stereotactic
frame under microelectrode guidance. RESULTS: Deep brain stimulation of the subthalamic nucleus
significantly improves motor performance, activities of daily living, and quality of life in advanced
Parkinson disease. In addition, it allows for marked reductions of antiparkinsonian medications.
Stimulation of the ventralis intermedius nucleus of the thalamus is an effective treatment for essential
tremor with sustained long-term effects. CONCLUSIONS: Deep brain stimulation is an effective
minimally invasive surgical treatment for Parkinson disease with sustained long-term benefits.
EJISST2008 June 8~10
61
EJISST-ID 112
Analyses of the propagation of canine distemper viruses (CDVs) in
HmLu hamster cells
Serag El-Deen Sultan and Kazushige Kai
Yamaguchi University
South Valley University
serageldeens@yahoo.com and kzkai@yamaguchi-u.ac.jp.
The propagation of 007Lm strain, one of the Asia 2 strains of CDV, in HmLu cells was studied in
comparison with Onderstepoort and Ac96I strain (Asia 1). The 007Lm strain could grow in HmLu cells
as Onderstepoort but not Ac961, and induced abnormal cytopathic effect (CPE) during passages of
infected cells shedding virus at low rate, and extending the infected cells gradually in the culture,
unlike the case of Onderstepoort. The abnormal CPE were revealed to develop slowly from infected
cells keeping normal morphology to giant cells which resulted by not only cell fusion but also nuclear
fusion. In the plaques formed by overlaying Vero-DST cells, colonies of infected HmLu cells were
found, indicating that the fusion events did not occur between the two cell lines. The 007Lm viruses
produced from HmLu cells at various passages revealed to be changed slightly in the relative
infectivity to HmLu cells versus Vero-DST cells (infectivity index). Also, a mutation leading to an
amino acid change was found in F but not in H gene of CDV in the virus sample produced at the 7 th
passage. Comparison of the infectivity index with HmLu, rat NRK, mouse NIH3T3 or ddY mouse
embryo cells revealed that 007Lm scored a relatively high index in HmLu cells but not in the other
cells. These results indicated that the Asia 2 strains but not Asia 1 strains can grow in HmLu cells and
hamsters but neither rats nor mice can be natural host to Asia 2 strain of CDV.
EJISST-ID 122
Characterization of a minor human NK cell sub-population, CD56dim16cells
Omar Dessouki and Seiji Okada
Kumamoto University, Japan
Suez Canal University, Egypt
dromarof@hotmail.com
Natural killer (NK) cells consist of CD56bright, CD56dim16-/+, and CD56-16+ subsets. CD56 dim16- subset
is a new minor subset that is found in both peripheral blood (PB) and cord blood (CB). We compared
this subset to different NK subsets in both CB and PB, regarding percentage, adhesion molecules,
functional molecules, degranulation activity, and cytokine secretion. CD56 dimCD16- subset appeared to
be harboring both, degranulation activity, and cytokine secretion abilities. The expression levels of
Granzyme A, B and PFN were decreased in the order of CD56 dim16+>CD56dimCD16->CD56bright cells.
In contrast, CD94 and Granzyme K expression levels were increased. NK stimulation with K562 cells,
stimulated secretion of IFN-γ by CD56dimCD16- subset only. There was significant difference between
CB NK and PB NK CD56dimCD16- subset expression of IFN-γ, with PB NK subset secreting higher
amounts. We analyzed CD107a as a marker of degranulation and cytotoxic activity. CD56dimCD16subset showed the highest expression level of CD107a, compared to other subsets. Degranulation level
was higher in PB than CB. Our results suggest that CD56 dimCD16- subset might be an intermediate
maturation stage in the NK development, and that higher secretion of IFN-γ by this subset in PB might
be playing a role in PB NK higher cytotoxic activity.
EJISST2008 June 8~10
62
EJISST-ID 125
Molecular epidemiological study on Hepatitis viruses in Ismailia Egypt
Ahmed Ibrahim Youssef and Yoshitak Hayashi
Kobe University
Ismailia University
ahmedyoussef22@yahoo.com.au
Background: Hepatitis virus exists throughout worldwide and is a major global public health problem,
because sometimes induce acute and chronic liver diseases. The prevalence of viral carriers and clinical
characters are geographically different. Although Egypt is a hyper endemic area of viral hepatitis, the
carrier rate and viral genotypes have not been sufficiently evaluated. Objectives: Our aims are to
examine the prevalence of carriers of hepatitis B (HBV), hepatitis C (HCV), hepatitis D (HDV) and
hepatitis E (HEV) viruses among patients having high liver enzyme in Ismailia University Hospital.
Additionally, we focused on the genetic variability and genotype-related differences in each hepatitis
virus. Study design: In the present study, we investigated serological and molecular-based
epidemiological survey of hepatitis viruses among 214 patients having elevated liver enzymes in
Ismailia province, Egypt. Viral RNA/DNA was extracted and genotypes of HBV, HCV and HDV were
identified by PCR-direct sequencing and phylogenic analysis. Results: Of 214 individual tested, HBVDNA was detected in 131 cases (61.2%), though 10 cases (4.7%) were positive for HBV surface
antigen. HCV-RNA was detected in 90 cases (42%) and 156 cases (72.9%) were positive for anti-HCV
antibody. HDV-RNA was detected in 24 cases (11.2%). 5 cases (2.3%) were positive for anti-HEV
antibody, but HEV-RNA was not detected. The most common genotypes were HBV-genotype C
(80%), HCV-genotype 4a (84%) and HDV-type I. Conclusion: Our results suggest that HBV and HCV
are widespread in Ismailia Province and have led to a high incidence of liver diseases. Moreover there
is a genotypic variability that may be characteristic to the Suez canal area or even the North East part of
Egypt, that may be differ that other areas of Egypt .
EJISST-ID 123
AP-1 and NF-κB are key regulators of Toll-Like Receptor 3 signaling
pathway: an in silico prediction
Mohamed Helmy, Masaru Tomita, Masa Tsuchiya and Kumar Selvarajoo
Keio University, Japan
Al-Azhar University, Egypt
kumar@ttck.keio.ac.jp, tsuchiya@ ttck.keio.ac.jp
Toll-Like Receptor (TLR) 3, an intracellular pattern recognition receptor, invokes an innate immune
response upon recognition of viral dsRNA or Poly I: C (dsRNA synthetic analog), and plays a crucial
role in defending the body against viral infections. Stimulated TLR3 triggers a TRIF-dependant
response leading to the activation of transcription factor (TF) NF-κB, AP-1 and IRF3/7 resulting in
induction of pro-inflammatory cytokines such as TNF- and IL-6. The malfunction of this signaling
contributes to pathogenesis of many viruses e.g. influenza A and major illnesses e.g. autoimmune
diseases. Although there have been extensive studies on TLR3 pathways, understanding the dynamic
behavior and the regulation mechanism of this signaling remain major challenge. In this study, we
adopted systemic approach integrating computational simulation and time-course experimental data to
understand and control the pro-inflammatory response in TLR3 signaling, using an in silico TLR3
model to simulate the time-course activation profiles of TFs; NF-κB, AP-1 and IRF3/7 and induction of
key pro-inflammatory cytokines TNF-α and IL-6 and compare the model simulation with similar
experimental results. In order to find the best target to regulate the malfunction pro-inflammatory
response, we performed in silico knock-outs and knock-downs of all known molecules in TLR3
pathway and found double downregulation, but not abolishment, of AP-1 and NF-κB gives the
-α and IL-6 in Poly I:C response. These results suggest that AP-1 and NF-
EJISST2008 June 8~10
63
κB are key transcription factors of TLR3 signaling as well as IRF3/7. Therefore, double targeting of
AP-1 and NF-κB should be considered for controlling viral and pro-inflammatory diseases.
EJISST-ID 129
Identification of cells that have hematopoietic activity in the placenta of
mouse embryo
Gomaa Ahmed and Taga Tetsuya
Kumamoto University
Suez Canal University
arsgomaa@gmail.com
The discovery of a major hematopoietic stem cell (HSC) pool in midgestation mouse embryo has
defined the placenta as an important anatomical site that participates in HSC development. Placental
hematopoietic activity culminates in a rapid expansion of the definitive HSC pool, which enables
placenta to harbor a large pool of hematopoietic stem cells especially during midgestation (embryonic
days (E) 12.5-E13.5). In this study, we examine the flow cytometric pattern of placenta cells, in the
view of CD45 and c-Kit expression, in the E10.5 to E15.5 and determine which type of these cells have
the highest ability to differentiate into hematopoietic cells by both co-culture with OP9 stromal cells
and performing colony forming assay in methylcellulose. We found the placenta of mouse embryo in
the E10.5 to E15.5, that, only propidium iodide (PI) negative CD45 +c-Kit+ cells when co-cultured with
OP9 stromal cells have the ability to form cobble stone colonies which believed to have hematopoietic
differentiating ability. When cultured in methylcellulose only PI -CD45+c-Kit+ population have the
ability to differentiate into hematopoietic colonies. In the E12.5 placenta in comparison with other
embryonic days, PI-CD45+c-Kit+ cells have the highest ability to differentiate into hematopoietic
colonies when co-cultured with OP9 stromal cells and in methylcellulose. Taken together, in the
placenta of mouse embryo, we can conclude that, PI -CD45+c-Kit+ cells from E10.5 to E15.5 have the
ability to form cobble stone colonies and to differentiate into hematopoietic colonies, and that the
E12.5 PI-CD45+c-Kit+ placenta cells have the highest ability to form cobble stone colonies and
differentiate into hematopoietic colonies .
EJISST-ID 148
Effect of local soft x-ray irradiation on rat skin: to establish radiationimpaired wound healing model
Ayman Atiba, Hiroshi Ueno and Yuji Uzuka
Gifu University
Kafr El-Sheikh University
Ayman_atiba2000@yahoo.com
Background/objective: Soft x-ray has a delayed effect on wound healing. The objective of this study is
to develop a model of soft x-ray irradiation-impaired healing using a full thickness skin wound excision
on rat. Methods: Wistar rats were exposed to a single dose of soft x-ray irradiation (6Gy in group I and
3Gy in group II) at a well-defined area on the back of each animal. All rats were anaesthetized and a
full thickness wound excision (15 x 15 mm) was made on the center of the well-defined area. All
wounds were digital photographed on 0, 3, 6 and 10 days, and the area of each wound was measured
using image analysis system. The effect of the two doses was evaluated by the change in wound size,
which was calculated as the percentage of wound area relative to the original wound area (0 day).
Results: The percentage of the healed area in 3Gy group was 23.32% on 3 day, 60.28% on 6 day and
92.49% on 10 day. While in 6 Gy group, it was 13.5% on 3 day, 44.7% on 6 day and 82.5% on 10 day.
Conclusion: The higher doses of soft x-ray irradiation were still associated with delayed wound
healing. We would like to study more valuable doses of soft x-ray and their relation to the mechanisms
of delayed wound healing. After establishing a soft x-ray impaired wound healing model, we can study
the effect of new material to accelerate delayed wound healing.
EJISST2008 June 8~10
64
EJISST-ID 147
The Detection of Autophagy and Apoptosis in Pancreatic Beta Cells to
Investigate the Contribution of Autophagy for Islets to Survive During
Isolation and Transplantation
Hamed Elgendy, Teru Okitsu and Kazuhiko Fukuda
Kyoto University Hospital
Assiut University
hamed@kuhp.kyoto-u.ac.jp
Introduction: Autophagy is known to be an ordinary reaction in a normal cell under the stressful
condition and have an effect to protect the cell to degrade their constituents, which could prevent the
cell to die. However, the relationship between autophagy and cell death is not clarified yet. To
investigate this issue, we first needed to establish the simple system to detect autophagy and apoptosis.
Method: Using MIN6 that is a mouse pancreatic beta-cell line, we tested whether (MDC or acridine
orange stains) and DAPI staining to work to detect autophgy and apoptosis, respectively. Result: MIN6
cells showed MDC-stain positive even without any artificial stress and became significantly more
MDC stain-positive after two-hour nutrient starvation. MIN 6 cells started to show significantly DAPIstain positive after 24-hour nutrient starvation. Conclusion/Discussion: Staining with (MDC or acridine
orange) and DAPI could be the simple system to detect autophagy and apoptosis in pancreatic beta cell
line, MIN6. After confirming their reliability using western blot with LC3 antibody for autophagy and
flow cytometory with Annexin V staining for apoptosis, we are planning to apply this system to
investigate the possible contribution of autophagy in pancreatic beta cells of islets to their survival
during the isolation procedure and the grafting phase in islet transplantation.
EJISST-ID 085
The role of PROPELLER Diffusion Weighted Imaging and Apparent
diffusion coefficient in the diagnosis of sellar and parasellar lesions
Omar Mostafa Mahmoud and Kaoru Kurisu
Hiroshima University
Assiut University
omarmostafa2008@yahoo.com
Background: Measurements of apparent diffusion coefficient (ADC) from diffusion weighted imaging
(DWI) for differential diagnosis of intracranial lesions are now well established. Periodically rotated
overlapping parallel lines with enhanced reconstruction (PROPELLER) DWI is a multishot Fast spin
echo (FSE) sequence using the advantage of both FSE methods which have far less B0-related artifacts
and PROPELLER MRI which is oversampling of the region in the center of k-space. Objective: The
aim of this study is to evaluate the role of ADC using PROPELLER DWI weighted imaging in the
differentiation between various sellar and parasellar lesions. Materials and Methods: We
retrospectively studied the sellar and parasellar lesions that were newly diagnosed and operated
between October 2006 and November 2007 in Hiroshima University Hospital. This study population
consists of 54 patients: 38 pituitary adenomas (24 non hemorrhagic and 14 hemorrhagic), 7 Rathke’s
cleft cysts, 5 meningiomas and 4 craniopharyngiomas. A 3.0 Tesla MRI was used to obtain
conventional images and PROPELLER DWI. The ADC was measured by manually placing regions of
interest (ROI) on lesions. Results: The mean ADC value of hemorrhagic pituitary adenomas was lower
than the mean ADC value of non hemorrhagic pituitary adenomas (P<0.01) and that of Rathke’s cleft
cysts (P<0.01). The mean ADC value of meningioma was lower than the mean ADC value of non
hemorrhagic pituitary adenomas (P<0.05).There was no statistical difference between the ADC values
of Rathke’s cleft cysts, cystic pituitary adenomas and craniopharyngiomas. Conclusion: ADC is helpful
in differentiation between various sellar and parasellar lesions.
EJISST2008 June 8~10
65
EJISST-ID 167
Migration inhibitory factor and neuclear factor kabba B expression after
laparotomy and pneumoperitoneum
Anwar Tawfik Amin Ali and S. Kitano
Oita University
Assiut University
anwartawfik2010@yahoo.com
Background: Migration inhibitory factor (MIF) and proteolysis inducing factor (PIF) affect cell
proliferation and tumor progression by activation of nuclear factor kappa B (NFkB). We evaluated
pneumoperitoneum versus laparotomy on expression of MIF and NFkB. Methods: We used 4
experiments to evaluate the effect of laparotomy and Co 2 Pneumoperitoneum on MIF mRNA and
NFkB protein expression, tumor growth, weight loss and survival in mouse malignant peritoneal
dissemination model. Results: MIF mRNA, NFkB protein expression and total tumor weight were
significantly higher after laparotomy than pneumoperitoneum. Weight loss was significantly less and
survival was significantly longer after pneumoperitoneum than laparotomy. Conclusion: CO 2
pneumoperitoneum had a beneficial effect on tumor growth and survival compared with laparotomy.
This may be associated with less expression of MIF and NFkB after CO 2 pneumoperitoneum.
EJISST-ID 209
Species differentiation of eimerian oocysts in farms where no clinical
coccidiosis is noted
Nabila Osman and Hiroshi Sato
Yamaguchi University
South Valley University
Nabila_75@lycos.com and sato7dp4@yamaguchi-u.ac.jp
Chicken coccidiosis is an intestinal infection caused by the intracellular protozoan parasite of the genus
Eimeria, having a major economic impact upon the poultry industry worldwide including Egypt. To
reduce the economic loss due to coccidiosis, prophylactic feed medication or application of live
attenuated vaccines is generally recommended. In Japan, clinical coccidiosis became rare in big poultry
farms. In the present study, we examined the prevalence of coccidian infection in big poultry farms
where clinical coccidiosis is absent without use of prophylactic feed medication or application of live
attenuated vaccines. Examined 5 farms localized in Yamaguchi Pref. kept broiler chickens on litter
(3,000 – 5,000 chickens per pen), and more than 10 deposited fecal samples per pen were collected at
60 days of age. Coccidian oocysts were found in 86.7% of broiler fecal samples (105 / 121), and 38%
of positive samples contained more than 100 oocysts per gram. Since species differentiation by
ordinary microscopical examinations is not definitive, molecular species diagnosis using polymerase
chain reaction was applied to these oocyst samples. All 5 farms possess 2 to 3 Eimeria species such as
E. acervulina, E. tenella, E. maxima and E. mitis, and E. tenella believed to be highly pathogenic was
the most prevalent species in individual pens and found in all 5 farms. The study is in progress to
elucidate the reason(s) why clinical coccidiosis is well-controlled in Japanese big poultry farms in spite
of the presence of highly pathogenic coccidian species.
EJISST2008 June 8~10
66
EJISST-ID 218
Some morphological studies on the visual system of albino and
pigmented rat
Safwat A. M. A., T. Imagawa and M. Uehara
Tottori University, Japan
Menoufiya University, Egypt
Safwatali13@yahoo.com
There are many studies on the classification and distribution of retinal cells in rats. In scientific work,
albino rats are generally used as experimental animals. However, albino animals have some
abnormalities including visual system. In albino mammals, the retina and visual systems develop
abnormally. It has been believed that ganglion cell density is reduced in the central retina and rod cells
actually are deficient. However, albino animal’s retina is easily damaged by light. Thus, the reduced
ganglion cell density of albino animals may be caused by postnatal cell death. My study aims to
compare the visual system between albino and pigmented rats. As first step I am working to observe
the distribution of ganglion cells and cones of both albino and pigmented rat using whole mount retina.
Samples collect from both albino and pigmented rats of about 30 days old raised up in dark condition.
The whole mount retina is stained with toluidine blue or cresyl violet for ganglion cells, and
immunohistochemically with peanut lectin for cone cells. Whole mount preparations are advantageous
for examination of the spatial distributions and densities of the retinal cells.
EJISST-ID 229
The significance of rDNA sequence and lipopolysaccharide in the
pathology and biotechnology of Agrobacterium species
Hussam Hassan Arafat Hassan1, J-ney Bautista-Zapanta1, Katsuyuki Tanaka1 Hiroyuki
Sawada2 and Katsunori Suzuki1
1
2
Hiroshima University
National Institute of Agrobiological Sciences, Tsukuba
El-Minia University
hussamhassan77@yahoo.co.uk
The pathogenic Agrobacterium strains cause crown gall and/or hairy root diseases on broad range of
dicot plants. To manage disease in farm fields and greenhouses, it is sometimes required to track the
contamination route of the causative agents by classification below the species level. To develop plantbiotechnologically useful Agrobacterium strains from pathogenic strains, information on the variability
of strains as a whole, and each member within the species is very helpful. Thereby, we analyzed rDNA
sequence in 36 strains belonging to the three major pathogenic Agrobacterium species; A. tumefaciens,
A. rhizogenes and A. vitis. 16S rRNA gene sequence was highly conserved among each species.
Internal transcribed spacer (ITS) was much more variable than 16S rRNA gene but was well
distinguishable among the strains of each species. In addition, we analyzed lipopolysaccharide (LPS), a
major component of the outer membrane in Grame-negative bacteria. A. tumefaciens and A. rhizogenes
strains had high and low molecular weight LPS molecules (LPS I and LPS II, respectively). On the
contrary, every A. vitis strains had only a single LPS II band. Two A. tumefaciens strains exceptionally
contained no LPS I similarly with the A. vitis strains. Interestingly, the two exceptional A. tumefaciens
strains were contained in a small group in the ITS-based phylogenetic tree in which the exceptional
ITS-harbouring A. vitis strains were also contained. These results indicate that combination of ITS
sequence and LPS profile is a powerful tool to characterize Agrobacterium strains and tracking the
causative strains in the farm fields.
EJISST2008 June 8~10
67
SESSION 6: Biotechnology - Pharmacy
EJISST-ID 185
Total Synthesis of Kahalalide F Toward Elucidation of the biological
function concerning the oceanic production reason of active peptides
which are recently discovered
Mostafa Ahmed Sabet Ahmed Hammam and Uemura Daisuke
Nagoya University, Japan
National Research Center, Egypt
mostafa13sabet@yahoo.com
Kahalalides are a diverse family of peptides isolated form sacoglossam mollusk Elysia rufescens. The
family includes a variety of cyclic (Kahalalide A-F, K, O) and acyclic skeletons (Kahalalide H-J), but
its most relevant member is kahalalide F. The latter exhibits an interesting cytotoxic activity against
several solid tumor cell lines. In particular, hormone-independent prostate tumors have shown
sensitivity to kahalalide F both in vitro and in vivo phase I trial for prostate cancer and is currently in
phase II clinical trials for hepatocellular carcinoma, non-small cell lung cancer (NSCLC), melanoma,
lung and prostate cancers. Anti-infective activity against several bacteria, viruses and fungi has also
been described for kahalalide F, and could also find application in the treatment of opportunistic
infections related to AIDS. Kahalalide F and its synthetic analogues are the most promising compounds
of the Kahalalides family. To investigate the biological property of Kahalalide and its derivatives, an
efficient synthetic route is required which utilize a solid-phase synthetic strategy. Using these features
to synthesize organic molecules of complicated structure can be done efficiently. And it is possible to
promote the synthesis of the physiological active peptides and characteristic chemical compounds
powerfully. we would like to aim the elucidation of the biological function concerning the oceanic
production reason toward active peptides which are recently discovered. Via the research of the
boundary territory of biochemistry, you can say that it is the research which conceals the possibility of
developing new field.
EJISST ID 011
Plasmodium falciparum Guanosine Monophosphate Kinase:A New
Target for the Development of Anti-Malarial Drugs
Mahmoud Kandeel and Yukio Kitade
Gifu University, Japan
Kafr ElShekh University, Egypt
mkanelpharma@yahoo.com
For developing antimicrobial drugs, it might be suitable to select targets from pathways that are present
in the parasite but absent in human; however, even if the target was present in a parasite and a host,
slight structural differences will be beneficial to new drug optimization. The rational way of drug
development starts with the identification of new molecular targets critical for parasite life. In order to
find a new target for the development of anti-malaria agents, we identified and characterized guanosine
monophosphate (GMP) kinase from Plasmodium falciparum. The gene encoding this enzyme was
obtained by PCR, cloned into the appropriate sites in pQE30 plasmid, and heterologous expression was
carried out in E. coli. The enzyme was purified by affinity chromatography and enzyme kinetics,
substrate specificity and enzyme inhibition were measured. The obtained results, supported by aminoacids alignment, molecular modeling and site directed mutagenesis, indicates that Plasmodium
falciparum GMP kinase is structurally and biochemically distinct from other guanylate kinases. These
differences can be targeted to develop an efficient and selective inhibitor drugs.
EJISST2008 June 8~10
68
EJISST-ID 015
Prolongation of residence time of liposome by surface- modification
with mixture of hydrophilic polymers
Tamer Mohamed Shehata, Ken-ichi Ogawara, Kazutaka Higaki and Toshikiro Kimura
Okayama University, Japan
Zagazig University, Egypt
tamershehataa@yahoo.com
The objective of this study is to evaluate the biodistribution characteristics of liposomes surfacemodified with the mixture of polyethylene glycol (PEG) and polyvinyl alcohol (PVA) as a drug carrier
for passive targeting of drugs. The liposomes (egg phosphatidylcholine:cholesterol = 55:40, molar
ratio) modified with both PEG and PVA (4:1 molar ratio) (PEG4%/PVA1% liposome) provided the
largest AUC, which could be attributed to the smallest hepatic clearance of the liposomes. The liver
perfusion studies clearly indicated that lower hepatic disposition of PEG4%/PVA1% liposome was
ascribed to the decrease in its hepatic uptake via receptor-mediated endocytosis. Furthermore, the
amounts of whole serum proteins and of opsonins such as complement C3 and immunoglobulin G
adsorbed on PEG4%/PVA1% liposome were significantly smaller than those on the liposome solely
modified with PEG (PEG5% liposome). On the other hand, several proteins were adsorbed at larger
amount on PEG4%/PVA1% liposome than PEG5% liposome, and the protein identification by LCMS/MS suggested that some of those proteins including albumin might function as dysopsonins. The
decrease in the adsorbed amount of several opsonins and the increase in the adsorbed dysopsonins
would be responsible for its lower affinity to the liver and long residence in the systemic circulation of
PEG4%/PVA1% liposome.
EJISST-ID 033
Proteome approach for identification of Schistosomiasis japonica
vaccine candidate antigen
Ekhlas Hamed Abdel-Hafeez and Kenji Hirayama
Nagasaki University, Japan
Minia University, Egypt
ekhlash@yahoo.com
Experimental vaccination with radiation-attenuated cercariae (RAC) confers possible practical levels of
resistance to challenge infection by humoral and by cellular mechanism. Here, we aimed to identify
candidate vaccine antigens by using specific IgG antibody from RAC vaccinated miniature pig. Two
milligrams of crude soluble egg antigen (SEA) or schistosomal worm antigen preparation (SWAP) had
been fractionated using liquid two dimensional systems (proteome PF2D) consisted of high
performance chromatofocusing (HPCF) and high resolution reversed phase chromatography (HPRP).
Out of 42 HPCF fractions of SEA or of SWAP, 26 (61.9%) or 15 (35.7%) showed positive dot blot
reaction with RAC vaccinated serum respectively. Those positive fractions were applied to the second
HPRP column. One hundred and seven out of 26 x 96 of SEA fractions and 18 out of 15 x 96 SWAP
fractions reacted with RAC vaccinated serum. From positive fractions we chose 17 of SEA and 10 of
SWAP that had no reactivity to normal cercariae infected (NCI) sera and had single peak of 214 nm
and were sent to automated N-terminal amino acid sequencer based on in situ Edman Reaction. Four
sequences were obtained and applied to the homology search in NCBI data base. Totally eight
candidate genes were listed up and their cDNA clones from schistosomula stage were obtained. Two of
the recombinant proteins (AAW27472.1 and AXX25883.1) showed strong reactivity with the RAC
vaccinated serum but marginal with NCI serum.
EJISST2008 June 8~10
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EJISST-ID 078
Two new biologically active compounds from marine fungi
Ahmed Atef El-beih, Sachiko Tsukamoto and Tomihisa Ohta
Kanazawa University, Japan
National Research Center, Egypt
aae2eg@yahoo.com
Recently, marine environment were recognized as a potent source for new metabolites. In our search
for new biologically active compounds from marine environment, we isolated two new compounds
from marine derived fungus. The first of which is (3S,4aR,5S,6R)-6-hydroxy-5-methylramulosin (1): a
new ramulosin derivative isolated from a marine-derived sterile mycelium together with three known
compounds (-)-5-methylmellein (2), (-)-5-hydroxymethylmellein (3) and (-)-(3R,4R)-cis-4-hydroxy-5methylmellein (4). The second one is Monodictyquinone (5): a new antimicrobial anthraquinone
isolated from a sea urchin-derived fungus Monodictys sp. together with three known compounds
pachybasin (6), chrysophanol (7) and emodin (8). Structure elucidation of the above mentioned
compounds was done using 1D and 2D NMR techniques including COSY, HMQC, HMBC and NOE.
Compound 1 showed cytotoxic activity of 65% against HeLa cells at a concentration of 50 µg/ml while
compound 5 didn’t show such activity but it exhibited antibacterial activity.
EJISST-ID 107
A novel approach using functional peptides for efficient nasal
absorption of insulin
El-Sayed Abdou Khafay Mariko Morishita and Kozo Takayama
Hoshi University
Suez Canal University
khafagy_elsayed@yahoo.com
Nasal insulin delivery has been widely investigated as an alternative route to subcutaneous injection for
peptides and proteins, such as insulin. Nevertheless, one of the major limitations of insufficient nasal
bioavailability of insulin is the low permeability through the nasal mucosa. Recent reports using
functional peptides referred to as cell-penetrating peptides (CPP), such as octaoligoarginine (R8) and
Penetratin (Pen), have been used to internalize different bioactive compounds into cells. The aim of this
study was to evaluate whether R8 and Pen can improve nasal absorption of insulin in rats. No insulin
absorption was observed following nasal administration of insulin solution alone; however, insulin
absorption increased after coadministration of the L- and D-form of R8 (L- and D-R8), and the D- and
L-form of Penetratin (D- and L-Pen). The effects on insulin absorption were more pronounced for Pen
more than for R8. L-Pen showed the strongest enhancing effect on insulin absorption. Dose-dependent
study showed direct relationship between L-Pen concentration and nasal insulin bioavailability. In
contrast, insulin bioavailability was dramatically decreased up on D-Pen concentration. Pretreatment by
the effective dose of L-Pen did not induce lactate dehydrogenase leakage, suggesting that L-Pen has no
untoward effect on the nasal mucosa. Our data demonstrate that coadministration of L-Pen increases
nasal insulin absorption markedly without causing detectable damage in cellular integrity. We conclude
that L-Pen is likely to become powerful tools for overcoming the low permeability of insulin through
the epithelial cell membrane, the major barrier to nasal insulin delivery.
EJISST2008 June 8~10
70
EJISST-ID 108
Highly sensitive and selective HPLC method with peroxyoxalate
chemiluminescence detection for the determination of doxorubicin and
its metabolite doxorubicinol in rat plasma
Sameh Abdel-Raouf Ahmed and Naotaka Kuroda
Nagasaki University
Assiut University
sameh_aa@yahoo.com
Doxorubicin (DXR) is a cytotoxic anthracycline antibiotic that has been used in the treatment of a
variety of neoplastic diseases. However, the clinical values of doxorubicin are limited by a cumulative
dose-dependent cardiomyopathy. DXR is rapidly metabolized in liver to the secondary alcohol
metabolite doxorubicinol (DXR-ol) that has been demonstrated to be cardiotoxic. In this work, we
developed a highly sensitive and selective HPLC method for the determination of DXR and DXR-ol in
rat plasma with peroxyoxalate chemiluminescence (PO-CL) detection. The method was based on
ultraviolet (UV) irradiation (254 nm, 15 W) of DXR and DXR-ol, which are fluorescent quinones, to
produce hydrogen peroxide in presence of a hydrogen atom donor such as ethanol and DXR or DXR-ol
was regenerated. The generated hydrogen peroxide and DXR or DXR-ol were monitored through POCL reaction by mixing with aryloxalate. The separation of DXR and DXR-ol by HPLC was
accomplished isocratically on an ODS column within 15 min. The method involves a simple one step
protein precipitation by methanol. The detection limits (S/N = 3) were 4.5 and 3.8 fmol for DXR and
DXR-ol, respectively. The recoveries of DXR and DXR-ol were greater than 91 % and the inter- and
intra-assay RSD values in rat plasma were 2.5–8.9 %. The method has been successfully used to study
pharmacokinetic profiles of DXR and its metabolite DXR-ol in rats after a single dose injection of 5
mg/kg DXR.
EJISST-ID 110
Antitumor hydrolysable tannins from wildly growing plant, Tamarix
nilotica, in the Egyptian oases
Mohamed A. A. Orabi, Shoko Taniguchi and Tsutomu Hatano
Okayama University
Al-Azahar University
M_a_orabi@yahoo.com
Tamarix nilotica, a common wildly growing plant in Egypt, is a member of the family Tamaricaceae
which produce unique class of hydrolysable tannins. Tannin-rich plants have been long used in leather
making, and as folk medicines as haemostatic, antidiarrheic, diuretic, antiseptic...etc and as consumed
food and beverages in Asia, Europe, North America and Africa. Recently found antitumor,
antiperoxidation, antivirus, hepatoprotective and other activities of tannins, which are largely
dependent on the structure of each tannin, enhanced the need for careful investigation of tannin-rich
plants. The unique linkages and structural diversity of hydrolysable tannins of family Tamariceae
promoted us to investigate Tamarix nilotica as one of its member for isolation, structural elucidation of
their tannin content and study of their biological importance. Five monomeric hydrolysable tannins
(Gemin-D, Remurin-A, Remurin-B, Tellimagrandin I and Tellimagrandin II), four dimeric
hydrolysable tannins (Hirtellin-A, Hirtellin-B, Hirtellin-E and Tamarixinin-A) were isolated for the
first time from Tamarix nilotica growing in Egypt. Identification of these compounds were carried out
based on 1H-, 13C- , two dimensional NMR spectroscopy and comparison with published data.
Hirtellin-B and Tamarixinin-A were reported to have significant host-mediated antitumor activity,
while Remurin-A and Remurin–B were reported to have potent immunopotentiator. The
biotechnological production of hydrolysable tannins using tissue culture of related species (Tamarix
tetrandra) was considered. Growth induction and establishment of the Tamarix tetrandra cultured
tissue have also achieved.
EJISST2008 June 8~10
71
EJISST-ID 113
Amidophosphane–Copper(I)-Catalyzed Asymmetric Conjugate Addition
of Dialkylzincs to Racemic 6-Substituted Cyclohexenones to Form 2,5Di- and 2,2,5-Trisubstituted Cyclohexanones
Khalid B. Selim and Kiyoshi Tomioka
Kyoto University
Mansoura University
Khbselim2000@yahoo.com
With the trend towards single-enantiomer pharmaceutical and chemical compounds, feasible laboratory
methods for the production of optically active intermediates and building blocks are of increasing
importance. Therefore, our laboratory has developed reactions utilizing a racemic mixture of
substituted cyclohexenones as substrates giving enantiomerically enriched substituted cyclohexanone
derivatives.1-3 We describe herein that asymmetric conjugate addition of dialkylzinc reagents to racemic
6-substituted cyclohexenones under the catalysis of chiral amidophosphane–copper(I) complexes gave
a mixture of nearly equal amounts of the corresponding trans- and cis-disubstituted cyclohexanones
with extremely high catalyst-controlled enantioselectivity.4 Epimerization with 1,8diazabicyclo[5.4.0]undec-7-ene (DBU) led to the conversion of these mixtures into the
thermodynamically more stable trans-2,5-disubstituted cyclohexanone as the major product with up to
96% ee in up to 96% yield. The regio- and stereoselective alkylation of the disubstituted cyclohexanone
products via the thermodynamically favored enolate gave 2,2,5-trisubstituted cyclohexanones with a
quaternary asymmetric carbon atom in good yield.
1) Q. Chen, M. Kuriyama, T. Soeta, X. Hao, K. Yamada, and K. Tomioka, Org. Lett., 2005, 7, 4439-4441.
2) T. Soeta, K. Selim, M. Kuriyama, and K. Tomioka, Adv. Synth. Catal., 2007, 349, 629-635.
3) T. Soeta, K. Selim, M. Kuriyama, and K. Tomioka, Tetrahedron, 2007, 63, 6573-6576.
4) K. Selim, T. Soeta, K. Yamada, K. Tomioka, Chem. Asian J., 2008, 3, 342-350.
EJISST-ID 135
MODULATION OF GENE EXPRESSION BY HUMAN CYTOSOLIC tRNase
ZL THROUGH SMALL NONCODING RNA
Reyad Elbarbary and Masayuki Nashimoto
Niigata University of Pharmacy and Applied Life Sciences
Tanta University
riadelbarbary@yahoo.com
The long form of mammalian tRNA 3′ processing endoribonuclease (tRNase ZL) can cleave any target
RNA at any desired site by recognizing a pre-tRNA-like or micro-pre-tRNA-like complex formed
between the target RNA and artificial small guide RNA (sgRNA), and can downregulate gene
expression in the cells. The recent discovery of hook-type sgRNA, the length of which is ~25 nt similar
to that of miRNA, inspired us to investigate whether miRNA can also function as hook-type sgRNA
(3). Here we show that a subset of human miRNAs can form hook structures and that hook-type
miRNAs can guide target RNA cleavage by human tRNase ZL in vitro. If these miRNAs really work as
sgRNAs in the cells, tRNase ZL would need to exist in cytosol and a part of miRNA molecules would
need to exist in a pool free from RISC. We found that indeed tRNase ZL exists ubiquitously in a cell
and also detected miRNA molecules in the free pool. We also present in vivo data indicating that
miRNA downregulates gene expression through directing mRNA cleavage by cytosolic tRNase ZL.
Furthermore, we discovered in human kidney 293 cells extracts various new small non-coding RNAs
(ncRNAs) including piRNA-like 5′-half-tRNAs and 28S rRNA fragments, co-immunoprecipitated with
tRNase ZL, and demonstrated that these ncRNAs also work as sgRNAs for tRNase ZL in vivo as well as
in vitro. Taken together, the present data suggest that human cytosolic tRNase ZL modulates gene
expression through various types of small ncRNAs.
EJISST2008 June 8~10
72
EJISST-ID 155
Synthesis and properties of 1’-disubstituted Nucleoside Analogues
Tamer M. Nasr, Yosuke Taniguchi and Shigeki Sasaki
Kyushu University, Japan
Helwan University, Egypt
pharmtamer@yahoo.com
Nucleoside analogues constitute an important class of compounds with a variety of biological activities
such as antitumor and antiviral activity. They have also attracted much attention as a useful component
of synthetic oligonucleotides, which are used in a variety of studies relating to gene expression and so
on. As an approach to discover new nucleoside analogues for duplex and triplex formation, we are
interested in the synthesis of 1’-disubstituted nucleoside analogues to study their hybridization
behavior to nucleic acids or recognition properties in enzyme reactions due to their unique features in
base stacking and shape-recognition ability. In this work, we describe the synthesis of 1’-phenyl
substituted nucleoside analogues. We applied the conventional N-glycosidation method to the 1’phenyl-substituted D-ribose derivative to produce 1’-disubstituted nucleoside analogues with adenine,
guanine, cytosine and thymine nucleobases. Stereochemistry of these nucleoside analogues was
determined by 1H-COSY and NOESY measurements. However, these N-glycosidated compounds were
decomposed under mild acidic or basic conditions without cleavage of the protecting groups.
Stabilization of anomeric cation by the phenyl group may be responsible to instability. Further study is
now ongoing along this line to construct stable 1’-phenyl substituted carbocyclic thymidine analogues,
which can be incorporated into oligonucleotides for evaluation of its ability for duplex and triplex
formation.
EJISST-ID 175
Modulatory effects of 5-Fluorouracil on the rhythmic expression of
circadian clock gene: a possible mechanism for chemotherapy-induced
circadian rhythm disturbances
Ahmed M. Hamdan and Ohdo Shigehiero
Kyushu University
Misr International University
Ahmed_hamdan2004@yahoo.com
The circadian clock system is necessary to adapt endogenous physiological functions to daily variations
in environmental conditions. Abnormality in circadian rhythms, such as the sleep-wake cycle and the
timing of hormonal secretions, is implicated in various physiological and psychiatrical disorders.
Recent molecular studies have revealed that the oscillation in the transcription of specific clock genes
plays a central role in the generation of twenty four hour cycles of physiology and behavior. It has been
noticed that patients receiving chemotherapeutic agents experience disturbances in their behavioral and
physical performances including circadian rhythms. To explore underlying mechanism of
chemotherapeutic agent-induced disturbance of the rhythms, we investigated the influence of 5flourouracil, one of the most widely used a chemotherapeutic agent for treatment of cancers, on the
expression of clock genes. Treatment of cultured NIH3T3 cells with 5-flourouracil for forty eight hours
resulted in significant reduction of mRNA levels of Period1 and Period2 without affecting the cell
variability. However, treatment with the same amount of Uracil, a structural analog of 5-flourouracil,
had little effect on the expression of clock genes. Consistent with its inhibitory actions, continuous
administration of 5-flourouracil into mice attenuated the oscillation in the expressions of Period1 and
Period2 in the liver and suprachiasmatic nuclei, the center of the mammalian circadian clock. These
results reveal a possible pharmacological action by chemotherapeutic agent 5-flourouracil on the
circadian clock mechanism, which is the underlying cause of its adverse effects on twenty four hour
rhythms in physiology and behavior.
EJISST2008 June 8~10
73
EJISST-ID 227
Importance of D-Amino Acid Oxidase Enzyme in Biotechnology
Rabab M. Abou El-Magd and Kiyoshi Fukui
The University of Tokushima, Japan
Mubarak City for Science and Technology, Egypt
rabab.abou.elmagd@gmail.com
Recombinant proteins are widely accepted as an effective and innovative class of therapeutics. Because
of their biological specificity, protein therapeutics can provide exceptional potency with minimal side
effects and develop a new treatment of unmanageable diseases, like different types of cancer, CNS
diseases and HIV. D-Amino acid oxidase (DAO) catalyzes oxidative deamination of D-amino acids
(steroisomers of naturally occurring L-amino acids), producing 2-oxo acids, hydrogen peroxide and
ammonia. In higher animals DAO is mainly present in the kidney, liver and brain. However, since its
substrates (D-amino acids) are considered very rare in higher animals, the physiological role of DAO
has been enigmatic, especially in human brain, since its discovery in 1935. Human DAO has been
recently established to be involved in the oxidation of D-serine, an allosteric activator of the NMDAtype glutamate receptor in the brain, and to be associated with the onset of schizophrenia. This enzyme
has several current and potential biotechnological applications, for instance, the production of keto
acids, chiral intermediates for antihypertensive drugs, biosensors, many semi-synthetic cephalosporins
and anticancer drugs. The aims of the recent study are: (1) Production of human DAO on shake-flask
level. (2) Test the effect of different antischizophrenic drugs on the activity of h-DAO. (3) Examine its
structure-activity relationship using site-directed mutagenesis. (4) Bioprocess development of the
production of h.DAO on the bioreactor level.
EJISST-ID 200
The effects of extracellular acidic environments on T-cell differentiation
Amany abdelrehim bekhit and Hiroshi Kobayashi
Chiba University
Minia University
umkareem05@yahoo.com
Metabolic acidosis is among the most common abnormalities seen in inflammatory loci or solid
tumors. In the recent studies there are some evidences suggesting that acidic condition has effect on the
immune response in mammalian cells. In immune system, T cells especially play a key role in
regulation of other immune cells. Therefore, we have focused in our study the influence of lower pH on
the differentiation of T-helper (Th) cells in Jurkat T cells towards Th1 or Th2 cells. The development
regulation of T helper cell is critically important to form and effectiveness of acquired immunity upon
stimulation with antigen, they begin a process of differentiation that including production of a specific
pattern of cytokine. The Th1 cell population is characterized by the production of interferon-γ (IFN-γ)
and directly cell-mediated immunity against intracellular pathogens, whereas the Th2 cell population
transcribes the linked cytokine genes encoding interleukin (IL-4), IL-5, and IL-13 that are involved in
defense against extracellullar parasites and allergic reaction. Recently, several transcription factors that
control Th1/Th2 cell differentiation were identified. Among them, GATA-binding protein-3(GATA3)
appears to be a key factor for Th2 cell differentiation. While Th1 cell is regulated by transcription
factors T-box expressed in T-cells (T-bet). In the present study, we analyzed the expression of those
transcription factors by RT-PCR using total RNA isolated from Jurkat T cell under neutral and acidic
conditions. Our data shown that T-bet transcriptional level was no significantly changed in acidic
medium compared to neutral medium .whereas, GATA3 transcriptional level was appear to be high in
acidic medium than neutral medium. Next, we sought to confirm further these result with Western blot
analysis. So, these studies will lead us to know how T cell differentiate under acidic environments.
EJISST2008 June 8~10
74
EJISST-ID 217
New sesquiterpene lactones from Daucus glaber (Forssk.) Tell. F.
Umbelliferae
Amal Ahmed Atwa Sallam and Koichi Takeya
Yokyo University of Pharmacy and Life Sciences
Monsoura University
amal14sallam@yahoo.com
[Objective]: Isolation and structural elucidation of new compounds from Daucus glaber (Forssk.) Tell.
[Material and Method]: The aerial parts of the herb were collected at the flowering stage from The
Northern region of The Nile Delta, Egypt where it grows wildly. The n-hexane fraction of the
methanolic extract yielded a white precipitate during evaporation. This precipitate was further purified
by a series of Rp-HPLC steps. Structural elucidation was carried out depending on NMR experiments
besides x-ray crystallography. [Results]: A series of sesquiterpene lacones of the guaianolide type,
DG1-DG8 were isolated. DG1 and DG4 are known while the other 6 sesquiterpene lactones are new.
EJISST-ID 220
Role of β-Hydroxy--Trimethylammonium Butyrate and Ubiquinone in
Combating the Deteriorative Effect Induced by CCl4 in Rat’s Liver
Asmaa M. Bayoumi , Atef E. Abd El-Baky, Sanaa A. Ali and Laila M. Faddah
Kyushu University, Japan
Minia University, Egypt
semsembio2004@yahoo.com
Cirrhosis is a chronic and irreversible condition, in which liver cells are progressively destroyed. It can
lead to loss of liver function and eventually, death. This research provides an information about the
mechanisms of liver injury induced by CCl4, and determines the influence of administration of Lcarnitine or/and CoQ10 as prophylactic agents against CCl4 deteriorative effect. The study was carried
out on 80 adult male albino rats divided into eight groups, 10 animals each, as follows: four normal
groups (control, treated with L-carnitine, treated with CoQ10, and treated with a combination of Lcarnitine and CoQ10) and four cirrhotic groups treated with CCl4 (control, treated with L-carnitine,
treated with CoQ10, and treated with a combination of L-carnitine and CoQ10).Liver cirrhosis was
induced by s.c. injection of a single dose of CCl 4 (1 ml/kg). L-carnitine (50 mg/kg/day) was given i.p.
for four successive days 24 hours before CCl4 injection, and CoQ10 (200 mg/kg) was given as a single
i.p. dose 24 hours before CCl 4 injection. Animals were sacrificed 24 hours after CCl 4 injection, blood
samples were withdrawn and liver tissue samples were homogenized. The levels of the following
parameters were determined: hepatic reduced glutathione, serum ALT and AST, hepatic lipid
peroxides, hepatic vitamin C, hepatic and serum total protein, serum albumin, serum sialic acid, serum
nitrite, and serum and hepatic total LDH activities and LDH isoenzymes. The obtained data revealed
that CCl4 injection produced a significant decrease in reduced glutathione content, vitamin C, total
protein and albumin levels. However, there was a significant increase in serum ALT and AST
activities, lipid peroxides, sialic acid, nitric oxide, serum and hepatic total LDH activities. On the other
hand, groups treated with L-carnitine or/and CoQ10 prior to CCl4 injection showed an improvement in
most parameters when compared with cirrhotic control group. It has been concluded that L-carnitine
and coenzyme Q10 have a pronounced prophylactic effect against liver damage induced by halogenated
alkanes such as carbon tetrachloride.
EJISST2008 June 8~10
75
EJISST-ID 303
Diagnosis of human malaria parasites in mosquitoes
Omar Sayed Omar and Yusuke wataya
Okayama University
AlAzhar University
marzoukmo@yahoo.com
Since the discovery of malaria parasites by Laveran in 1880, traditionally malaria has been diagnosed
by microscopically examining Gemisa-stained blood films. This conventional malaria diagnostic
method, is simple, does not require highly equipped facilities and in most cases enables differentiation
among the four species of malaria parasites. Nevertheless, this method is labor-intensive and requires
highly trained microscopists for accurate identification especially when the number of parasites is very
low. We have developed a simple diagnostic method "microtiter plate-hybridization" (MPH) for the
purpose of detecting human malaria parasites by those without experience in identifying 4 species of
human malaria parasites, or detecting low-grade parasitemia. In this method, the target DNA sequence
of the 18S ribosomal RNA gene is amplified by polymerase chain reaction and hybridized with the
species-specific probes immobilized on a microtiter well. The PCR products bound on a well are
visualized by the biotin-streptavidin system and the following chromogenic reaction. In this
symposium, I will introduce our research results about detection and distinguish of the malaria
parasites in the mosquitoes using MPH technique.
EJISST-ID 234
Total Synthesis of Aza Analogues of Flustramide alkaloids by Using Aza
Pauson-Khand Reaction
Yaseen A. Mosa and C. Mukai
Kanazawa University
Al-Azhar University
yaseenorganic@yahoo.com
Flustramide alkaloids have the pyrrolidinoindoline ring system as a core framework. These alkaloids
display interesting biological activities. For example, flustramide bearing two prenyl substituents at C 3
and N8 was found in marine bryozoan flustra foliacea exhibits muscle relaxant activity affecting
skeletal and smooth muscle while debromoflustramine which was detected in the skin of the
ASustralian frog pseudophyrne semimarmorata is known antibacterial agent active against vancomycin
resistant Entercocci and methicillin-resistant Staphylococcus aureus. This work is aimed to prepare
several aza analogues of flustramide (5) by using newly developed procedure based on Pauson-Khand
reaction. Treatment of 2-amino-3-iodopyridine (1) with trimethylsilylacetylene under the Sonogashira
conditions would afford the coupling product (2), which will be subsequently treated with triphosegene
to give the pyridine-fused alkyneurea derivatives (3). This intermediate will be transformed into the
corresponding alkynecarbodimide (4). The aza Pauson-Khand reaction of (4) will afford compound (5)
which will be treated with NaCNBH3 under acidic conditions in the presence of 3-methyl-2-butenal to
provide the N-prenylated analogue (6). The hydroxyl group of (6) is activated by acetylation (7),
followed by subsequent exposure to lithium di-ter-butylbiphenylide at -75 oC must furnish the target
molecule (8).
EJISST2008 June 8~10
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EJISST-ID 240
Utilization of cell penetrating peptides for enhancing intracellular
delivery of nucleic acids encapsulated into liposomes: Octaarginine
versus octalysine
Ayman El-Sayed 1,2,4, Ikramy A Khalil 1, Kentaro Kogure 3 and Hideyoshi Harashima 1,2.
1
Faculty of Pharmaceutical Sciences, Hokkaido University, Japan, 2Graduate School of Life Science,
Hokkaido University, Japan, and 3Kyoto Pharmaceutical University, Japan
4
Alexandria University, Egypt
ayman@pharm.hokudai.ac.jp.
Recently, we adopted a technology to package nucleic acids into liposomes followed by liposome
surface modification with various devices for efficient intracellular delivery of nucleic acids. In this
study we compared the effect liposome surface modification with two cationic cell penetrating peptide,
octaarginine (R8) and octalysine (K8), on the intracellular trafficking of liposomes encapsulating
nucleic acids. The extent and mechanism of liposome uptake were studied using flow cytometry, and
the transfection activity of liposomes encapsulating luciferase plasmid DNA was determined in NIH
3T3 cells in the absence or presence of chloroquine. Intracellular trafficking of liposomes and the
endosomal escape efficiency of the nucleic acid cargo was quantified using confocal laser scanning
microscopy. Silencing effect of liposomes encapsulating anti-luciferase siRNA was tested in HeLa
cells stably expressing luciferase. Modification of liposome surface with K8 (K8-Lip) increased gene
expression levels by 20-fold over unmodified liposomes. Interestingly, modification with R8 (R8-Lip)
enhanced gene expression 320-fold over unmodified liposomes and 17-fold over K8-Lip.Regarding the
uptake, R8-Lip and K8-Lip were taken up primarily via macropinocytosis with comparable efficiency.
The extent of escape of plasmid DNA encapsulated in R8-Lip from endocytic vesicles to the cytosol
was double that of K8-Lip. Anti-luciferase siRNA encapsulated in R8-Lip resulted in higher gene
silencing than that encapsulated in K8-Lip. In conclusion, compared to K8, R8 on the liposome surface
allowed efficient escape of nucleic acids encapsulated in liposomes from endocytic vesicles to the
cytosol. The study proved the utility of R8-Lip for cytosolic and nuclear delivery of nucleic acids.
EJISST-ID 188
A new Route to Synthesis of Biologically Active Azaindoles
Montaser Shaykoon Ahmed and C. Mukai
Kanazawa University
Al Azhar University
monoceutical@yahoo.com
Instead of hag number of therapeutic agents continuously introduced to market, most of this agents
suffering from many drawbacks such as unwanted pharmacological action. The looking for potent and
safe without or with minimum unwanted pharmacological action attracted the attention of many
research groups. Azaindole derivatives have attracted much attention due to their physicochemical and
pharmacological properties. Azaindole can be considered as bioisostere of indole moiety. Based on the
above finding the objective of this work is synthesis and evaluation of biological activity of 5, 6 and 7azaindole derivatives using newly developed procedure, in an attempt to develop more potent and safe
therapeutic agents. Stille coupling reaction of 2-Amino-3-iodopyridine derivative 1 with stannyl allene
2 provide the coupling product 3, which was subsequently transformed into 7-azaindole derivative 4 by
base treatment. According to this newly developed procedure, we are now trying to prepare other types
of biologically active azaindole derivatives such as 5-and 6- azaindoles.
EJISST2008 June 8~10
77
EJISST-ID 321
Recombinant Human Growth Hormone (rHGH) Production
Hanna Hammad
Theodour Bilharz Research Institute, Egypt
hanna_hammad2004@yahoo.com
This study aims to analyze the main synthetic and purification strategies that will be used for the
production of (rHGH) giving special consideration for utilization of the method in the Biotecnology
industry. To achieve this goal,our proposed protocol included cloning of human growth hormone gene
into expression vector, production of its protien in prokaryotic system and using modern separation
techniques to obtain high yield with great purity for clinical application. The human growth hormone
gene cluster is located on the long arm of chromosome 17 and consists of five highly sequencesconserved genes aligned in the same transcriptional orientation. Placental and pituitary 22-kDahGH
show similar somatogenic activity, but the placental isoform has reduced lactogenic activity.In contrast
with the hGH-Ngene, the use of the alternative splice site generating a20-kDa isoform has been
documented for the hGH-V gene. Instead , a different splicing pathway in which interon D is retained
in the processed messenger RNA (mRNA) has been identified,predicting a 230- amino acid protein
called hGH-V2.This 26-kDa isoform of the the hGH-V gene shows complete sequence divergence in
the carboxy- terminus compared with 22-kDahGH-V and it is presumably a membrane- bound protein.
In this study, two new transcripts of the hGH-V gene are described.One of the transcripts uses the same
alternative splices acceptor site within exon 3 as seen in the hGH-N gene predicting a 20-kDa isoform
of the hGH-V gene. the other transcript, which we refer to as hGH-V3 is generated by the use of an
alternative splice donor site near the end of the fourth exon causing a 4-bp deletion. The hGH V3
transcript predicts a 24-kDa protein with 219 amino acids, in which the first 124 amino acids are
identical to those of placental 22-kDa hGH,wherese theremaining carboxyterminal residuse shows a
complete sequence divergence.
EJISST2008 June 8~10
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SESSION 7: Human Science
INVITED-TALK
For Interchange and Collaboration between Islamic Economics and
Buddhist Economics
Hiroyuki Akashi
Professor, (Former Director of International Center of Komazawa University),
Faculty of Business Administration, Komazawa University,
akashi@komazawa-u.ac.jp
On the 14th January 2008, “AGREEMENT FOR COLLABORATION IN RESEARCH, EDUCATION
AND TRAINING BETWEEN CAIRO UNIVERSITY AND KOMAZAWA UNIVERSITY” was
concluded at Cairo University. Komazawa University (KU) is one of the main Japanese Buddhist
universities. The “Spirit of Foundation” of KU is based upon “the Doctrine of Buddhism and the Spirit
founded by Soto School”. KU has a unique institution named BUKKYOKEIZAI KENKYUJO (The
Institute of Zen Buddhism and Economics). This institute was established in 1966. The purpose of the
institute is the “Research on Buddhist Economy, especially Economy tied to Zen”. I hope that the
Agreement will contribute to new collaboration between Egypt and Japan. I also hope that the
Agreement will contribute to understanding between Arabic, African and Islamic Areas and Buddhist
Areas. There is one more hope connected to this Agreement. It is a new born opportunity of
interchange and collaboration between Islamic Economics and Buddhist Economics. Both Economics
have been developing from the time of the latter half, especially the last quarter of 20th Century. The
interchange and collaboration between the both academic areas has a possibility of new development of
Economics or Economic Sociological Studies. I would like to investigate this new possibility for
scientific and practical development in my report.
EJISST-ID 043
Policy Networks and Public Policy Making Process: A Comparative
Analysis to the Education Policy Reforms and the ODA Policy Reforms
in Japan during the 1980s and the 1990s
Ahmed M. Abd Rabou
Hokkaido University
Cairo University
Abdraboh2004@yahoo.com
During my masters work I have studied the topic of "Policy Networks and Public Policy Making
Process: A Case of Education Reforms in Japan During the 1980s". Questions like: How, When, in
What mechanisms, and to What extent can a political actor influence the policy making process in
order to get its policy, its priorities, its aims, and its interests adopted by a given political system?,
explain the main problems I dealt with in my research. The aim of my research was to discover the
main ways, tactics, and techniques by which a given political actor is able to control the policy making
process. My research project will be a continuation to my master work. However, the research main
target has focused on a limited period, the 1980s, and analyzed only one dimension of the public policy
making process, namely the internal public policies, which is the education reform in my case.
Therefore, it is the aim of my research project to extend the analysis of the master work on two
dimensions; horizontally and vertically. Horizontally the project aims to analyze the policy making
process in Japan in both the 1980s and the 1990s. The analysis of the master project focused mainly on
the 1980s, however, in the 1990s more political as well as economic changes occurred in the Japanese
political system. Economically, the booming Japanese economy has slowed down to some extent
EJISST2008 June 8~10
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causing a variety of constrains on the Japanese decision makers. Politically, the decision making
context in Japan has witnessed some changes since the Liberal Democratic Party lost power after a long
period of manipulating the decision making context, even though this loss of power was for a very
short time (1993-96), it affected the traditional balance of power within the Japanese political system
and gave new fuel to the pluralistic theory of policy making in Japan.
EJISST-ID 065
Social policies in Egypt and how subsidies system can be rationalized to
benefit the poor
Maha Ahmed Khalil and Tanaka Hideaki
National Graduate Institute for Policy Studies, Japan
Cairo University, Egypt
mahafeps_2004@yahoo.com
Social policies and welfare state, two controversial debates prevailed on many academic fields and on
the state level. Especially in the era of a globalization, and most of the world countries are transforming
to capitalist market economies, which implies limited role of the state. Therefore, the traditional view
of the state role in providing many social services went under revision. Consequently this raised a
growing interest in the academic arena to investigate what are the best social policies that the state has
to maintain for the poor. Also, many of world countries are facing continues budget deficit and this
shall put more pressure on government social expenditure. Notwithstanding, many of those countries,
OECD countries, are maintaining high levels for social expenditure for social security and safety
networks. In this context as the Egyptian government introduced free market economy since the late
1970s. Gradually that trend implied the state withdrawal of providing many services in favor of the
private sector. However, under the imperfect market mechanism this implies that many of the poor
can’t have the access to such services. The state committed to protect the lower income classes and
poor by providing. Subsidies on food goods, education, and fuel price. However, a growing debate
prevails in Egypt suspecting the beneficiary of subsidizing policy. As the lower income classes and
poor don’t benefit from the subsidies or at least the poverty levels didn’t decrease. So, the main
question how the Egyptian government can rationalize the subsidizing policy in a way that makes the
real stakeholders benefit of it?
EJISST-ID 066
Environmental Security in the International Politics: A Comparative
Study between Japanese and American Policies
Nilly Kamal El-Amir and Fukagawa Yukiko
Waseda University
Cairo University
nkamalm@yahoo.com
As a result of the increasing awareness of protecting environment on the local, regional and
international levels, since 1970s the security studies have been expanded to include new dimensions
and concepts such as: human security, energy security and environmental security… Currently there is
little coherence around the world about environmental security’s definition, threats, and policy
responsibilities. However, it can be defined as: “The relationship between security concerns such as
armed conflicts and the natural environment”. In this respect, the project aims at introducing and
analyzing definitions of the concept of environmental security and its related concepts, as: Greens,
environmentalism…Also, it will try to explore the perspectives of government, business community
and Nongovernmental organizations (NGOs) of both US and Japan in environmental security. The
study raises the following question: To what extent can the mutual interests between Japan and the US
lead to a coordinated environmental (policy) perspective between the two countries? As Kyoto Protocol
is the world's first treaty to attempt to address global warming by limiting greenhouse gas
EJISST2008 June 8~10
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emissions, the period from 1997 to 2007 which followed the beginning of Kyoto Protocol negotiations
will be covered..
EJISST-ID 124
第二言語習得における母語干渉と誤用分析の研究
―エジプト人の日本語学習時の母語としてのアラビア語干渉とそれによる誤用の場合―
A Study about Interference of Mother Language and Misuse Analysis in
the Second Language Acquisition.
－in the case of Interference of Arabic language for Egyptians when studying
Japanese and the misuse caused by that－
Mohammad Ebdel-Rahman Eshiba and Satoshi MIYAZAKI
Waseda University
Ain shams University
moh_egypan27@hotmail.com
本研究は、筆者が母国であるエジプトの大学で行われている日本語教育から反省した課題に
ついての研究である。筆者はエジプト人の日本語学習時における母語としてのアラビア語干
渉というテーマに関心を持ち、母語干渉とそれによる誤用などが学習過程において、大きな
障害になることが十分考えられるということを主張したい。筆者は、日本語とアラビア語の
特徴が大きく違い、最も語構成が違う言語になっており、アラビア語と日本語の両言語を対
象にした研究が多くなされていないため、本テーマについて研究しようと考えたのである。
本論では、日本語とアラビア語の特徴を調べ、比較した結果を参考にしながら、アラビア語
を母語とする日本語学習者の日本語学習時の母語干渉とそれによる誤用について考察する。
一般には母語による発音面の干渉も極めて大きく、文法面、語彙面そして表現面の誤用も少
なからずあるが、ここでは文法面における誤用に絞って研究していきたいと考えている。
本稿でアラブ人の日本語学習過程における母語の影響について考察し、研究するために、実
際のデータを収集する。研究の参考になるのは、次である。
１．実際にアラブ人日本語学学習者を対象にして行うアンケート調査である。
２．筆者がエジプトの日本語教育の現場に入って行う学習者の日本語会話、そして教室での
実際の日本語使用の収録とそれの文字化と分析である。
３．本課題に関連する先行研究があれば、それを参考にする。
この研究の成果を使って何ができるのか、日本語教育に応用し、提言できることは何かを明
らかにしたい。そして今後の課題として、このような研究をして母語の影響による問題の解
決ができるようになれるかどうかという応用と実践の面、そして母語干渉などによる誤用を
防ぐことができるかどうかという点も取り上げたい。最後に、今後の最も重大な課題として、
母語干渉による誤用をなくし、または少なくするために、とられるべき対策、そして学習者
と教師に求められる役割は何かということについても真剣に考えるべきであることを強調し
たい。
EJISST2008 June 8~10
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EJISST-ID 295
中世文学における地獄と浄土の夢
Yousra Ashraf Mohamed Anwar and Tanaka Takako
Konan University
Ain shams university
babynonnastar@yhoo.com
「専願案養樂 莫忘三途苦」一遍の上人語録にはそういう歌がある。
一般的に、人々の生き方は、死んだ後の世界の概念に影響を与えていると考えられている。
死後の世界について古代の日本人は、黄泉の国というものを考えていたようであるが、仏教
の特に浄土教の考え方が日本に入ってきてから、地獄と極楽という二つの世界を考えるよう
になった。私は日本人が地獄と極楽をどのようなものとして考えていたかということに興味
を持ったので、卒業論文では、源信の『往生要集』を使って、その地獄と極楽の描写を調べ、
それとイスラムの地獄と天国のイメージを比較してみた。日本人の考え方を分かるためとか、
いろいろな習慣を説明するためには、この地獄と極楽について理解する必要があると思う。
いうまでもなくすべての点を調べることは困難である。これからの研究ではその文学的な描
写にしぼって研究するつもりである。つまり研究テーマは日本語文学における地獄と浄土の
描写である。
日本の地獄と浄土の描写は常におなじものではなく、だんだん変わってきた。これからの研
究では古代の資料から室町時代の資料まで使うつもりである。古代の作家はどうしてその描
写を書いたか、そして、この描写を通して何を伝えたかったであろうか。
これからの研究のために、今のところ『日本霊異記』、『日本往生極楽記』、『聖徳太子
伝』、『篁物語』『今昔物語集』、『目連救母経』、などにある描写に基づいて書くつもり
である。また、このテーマに関係がある和歌が見つかったら、それも使うつもりである。そ
して地獄草紙や浄土の絵巻などにある描写も研究するつもりである。
EJISST-ID 312
宮沢賢治の文学における「孤独感」
Amira Said Aly and Hiraishi Noriko
Tsukuba University
Cairo University
theprincessa1@hotmail.com
宮沢賢治は子供 . 大人を対象に多くの詩や小説を書いた、有名な作家である。賢治の文学を
取り上げ、分析した研究論文が数え切れないほど発表されたのは不思議ではない。様々な視
点からそれらの分析が試みられているものの、宮沢賢治の文学における「孤独感」という点
からの考察が不十分だと思う。筆者はこのテーマ「宮沢賢治の文学における孤独感」を追求
し、考察してみた。第一に、賢治の生涯における孤独感を、第二に『セロ引きのゴーシュ』
に託した孤独感、第三に『風のまた三郎』に託した孤独感を具体的に分析してきたと思う。
EJISST2008 June 8~10
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INVITED-TALK
Japanese Studies at Kansai University: Globalizing Our Campus
Yuriko Kite
Director, Center for International Affairs,
Professor, Institute of foreign Language Education and Research,
Kansai University
ykite@ipcku.kansai-u.ac.jp
Kansai University (KU) is one of Japan’s largest comprehensive universities with over six hundred
faculty members and twenty-seven thousand students: Faculty of Letters [BA and MA programs],
Faculties of Engineering (Engineering Science, Environmental and Urban Engineering, Chemistry
Materials and Bioengineering) [BS and MS programs] to name a few. Its Center for International
Affairs promotes exchanges of students and faculty, and provides Japanese as a Second Language as
well as Japanese studies programs for international students (470 per a year). KU has 43 university
partnerships in Asia, North Americas, Europe and Africa. KU and a university in Egypt have recently
begun a partnership. The partnership grew out of long term research and project collaborations between
scholars related to these two universities. Though small in number, the potential of this partnership is
large. There are many opportunities for expansion that can be explored within the interdisciplinary
projects involving Egyptologists, engineers, and archeologists to bring about an active student and
scholar exchange. In this presentation some of the ingredients that underpin this partnership’s potential
will be noted: The vision of a globalized KU campus, the commitment by the current administration,
research and project focus, and urban campus environment and facilities which support these new
projects. The talk will conclude with plans for the future including significant exchanges, especially in
branches of science and Japanese language or culture, between Kansai University and Egyptian
universities. The challenges we face in pursuit of our goals will also be pointed out.
EJISST-ID 313
Japanese Language Culture - Language
Hala Mahmoud Abd Elazim and Matsumura Yoshiko
Kyushyu University
Ain Shams University
halamimi@yahoo.com
日本語を話すエジプト人と断面調査した結果、ほとんどが微妙な点で日本語を完全に伝えら
れず、時には違った翻訳、通訳をしている事実を知った。聞いた言葉をそのまま訳してしま
うと話手が意図している意味とは違ってくることが多くある。それは日本語の微妙なニュア
ンスを理解せずしては完璧な日本語の情報伝達は不可能であるから。しかし言われている意
味と捕らえられている意味が違って来ると双方に誤解が生じることになる。なぜそのような
誤解が起こるかと調べるのに、「相手待遇理解」また「待遇コミュニケション」との研究に
進みたいと思っている。「待遇理解」は表現主体が表現した「文話」を理解する相手の理解
を考察することである。「待遇表現」は「表現主体」がある「表現」を「相手」「理解主
体」に使う表現である。しかし、場合によって、「表現」は理解されない、あるいは理解さ
れにくいことがある。この研究ではその「相手」がどのように「待遇表現」を理解したかと
「相手」の捉え方を考察する。私が専攻したい「待遇理解」は言語としてはマクロ的に思わ
れるが、この研究なくして日本語の曖昧な表現、表記を伝えることは困難であると思われる。
EJISST2008 June 8~10
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EJISST-ID 314
Modern Literature and Gender- Japanese Literature
Mohamed Momtaz Mohamed and Hirata Yumi
Osaka University
Ain Shams University
mmomtaz2002@yahoo.com
川端文学を批評するこれまでには膨大な数の研究があるのは周知のことである。特に、作者
が様々な角度から人生模様を織り成す多様性に富んでいる『山の音』は分析的な読みの意欲
をそそる作品である。川端作品の中で女性が初めて主人公の個性を発揮させる副次的な役割
を果たすのだけでなく、ちゃんとそれぞれの特有の性格を持っていて立体的に描かれている
女性が最も多く登場するにも関わらず、『山の音』に関するその先行研究の多くは男の主要
人物を中心に行われ、脇役の女性群を論じるの極めて少ない。また、『山の音』の評論文で
は女性に言及しても、ほんの少しのことで、作品の社会背景や家庭構成や主人公の心理描写
にとどまるだろう。それゆえに、私は本論で、『山の音』をはじめ、作家川端康成の女性に
対する考え方はいかなるものであったか、また彼にとって女性はどういう存在であったかを
代表的な作品を通じて追及し、戦後、川端氏の理想とする女性像を探っていきたいのである。
すなわち、素材となっている女性を抽出し、分析することによって、作者の特異な女性像を
つかみだすの本論の目的である。
EJISST-ID 316
Higher Education Privatization and the Planning for Educational Reform:
Malaysia as a Case Study 1996-2006
Ahmed Mohamed Nabawy and Kleinschmidt Harald
Tsukuba University, Japan
NCERD, Egypt
ahmednabawyjapan@yahoo.com
This paper deals with the Malaysian privatization experience. It will tackle three main issues; the
factors behind the establishment of domestic private universities, the privatization model applied in
Multimedia University and Universiti Tenaga Nasional, and the different types of privatization applied
to private universities in Malaysia. It will explain in detail the various forces that stood behind allowing
private universities to operate inside Malaysia. The analysis of key documents relating to the Malaysian
government policies of privatizing higher education institutions reveals the predominance of concerns
for maintaining equal access to higher education under the constraints enforced by the Asian economic
crisis. The government boosted privatization efforts for the purpose of reducing its financial burdens
while increasing the number of study places. The result has been a further rapid expansion of the
university system. Equity concerns overwhelmed the other aspects of providing higher education.
Although the privately operating universities professed to adherence to rigid quality standards,
achievement has been far from obvious. Much teaching could only be offered by hastily recruited
foreign faculty. Thus the dilemma reoccurred that had already haunted colonial higher education
institutions. Foreign faculty, mostly recruited from English speaking countries, have brought with them
their knowledge and educational habits and have been prone to organize teaching in accordance with
their training and personal experience. They have also restored much of the dependence of Malaysian
higher education institutions on western models, even though these models are no longer exclusively
colonial. Many newly founded private universities are focusing on teaching, predominantly at the
undergraduate level, rather than research. Quality measured in terms of educational autonomy has thus
suffered as a result of privatization. Last but not least, the total absence of government concerns for
social cohesion as a goal of education is telling. Under budgetary constraints, the government has not
EJISST2008 June 8~10
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only revoked the affirmative action policies that had benefited Malays, but has been reluctant to
support universities as potential facilitators of a public sphere.
EJISST-ID 311
福沢諭吉とムハンマド･アブドウの教育思想
-教育と政治の分立論をめぐって
Harb Hassan Kamal and Takamitu Shimamoto
Osaka University
Cairo University
harbosaka@yahoo.com
この研究では、19 世紀半ば以降、歴史的、社会的、政治的な背景を探りながら、日本とエジ
プトの近代における教育家、福沢諭吉（1835－1901）とムハンマド･アブドウ（1849－1905）
の教育思想を考察していく。とりわけ福沢諭吉とムハンマド･アブドウの、伝統思想との対決
の仕方の違いと西洋思想の受け止め方の違いなどを明確にすることを通して、福沢とアブド
ウの教育思想における共通性と差異、およびその理由を明らかにしようとするところに研究
の中心的なねらいがある。本論文は、両者の教育と政治の分立論を取り扱う。福沢は教育を
政治から分離するように主張するのに対して、アブドウは教育に政治が関わるべきであると
述べている。筆者は、福沢とアブドウの教育と政治の分立論を論じるに際して、教育・政
治・財政などの側面を検討することによって、最終的には日本とエジプトの近代化の問題の
一端が明らかになるのではないかと考えている。
EJISST-ID 317
“Continuity and Discontinuity in Japanese Foreign Policy toward the
Middle East: The Persian Gulf Wars” as a case study
Abeer yassin and Masataka kimura
Ibaraki University
Al- Ahram center for political and strategic studies
abeeryassin@yahoo.com
I am planning to study something like “Continuity and Discontinuity in Japanese Foreign Policy
toward the Middle East: The Persian Gulf Wars” as a case study. Accordingly, I would deal with some
issues like:

How Japan thinks about its foreign and security policies,

Japan’s role in the world in general and in the Middle East in particular,

Factors affecting Japanese foreign policy toward the Middle East comparing with
Japanese foreign policy toward the last two Gulf wars,

Factors which have the greatest impact on the decision-making of Japanese foreign
policy,

Impact of Japanese foreign policy on Arab-Japanese relations.
Dealing with issues of foreign and security policies are very important in having a clear vision of what
is desirable for the Japanese point of view. The following topics will be considered: policy-making
institutions, political parties, interest groups, public opinion, media, etc. Main contingent factors
affecting Japan’s foreign policy: economic, political, human values, national interests which we can
understand in a better way when we deal with one topic "war" in the same place "Gulf region" with the
same countries "mainly Iraq and the United States" in various regional, domestic, and international
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conditions. So, we can judge in a better way the importance of each factor (domestic, international on
one hand, economic, political, human values on the other hand.
EJISST-ID 184
Japanese demonstratives
Yasmine Samy Gamal ElDin and Ken Machida
Nagoya University
Ain Shams University
bonbon_83@hotmail.com
世界の諸言語には、二系列、三系列、あるいはそれ以上の系列を持つ指示詞があるが、日本
語の指示詞は三系列の範疇に入るのに対し、アラビア語の指示詞は二系列の範疇に入る。エ
ジプト人は日本語を学ぶ際、日本語の指示詞は「これ、それ、あれ」という三つに分けられ、
「これ」が話し手に近い物、「それ」が聞き手に近い物、「あれ」が話し手と聞き手の両方
から遠い物を指という風に教わる。しかし、現実に日本語の指示詞はそれほど単純なもので
はない。このことを踏まえ、本稿では日本語の指示詞「コ、ソ、ア」の特徴について議論す
る。
EJISST-ID 315
イスラム教．仏教における死後の世界
Reem Ahmed Saleh and Shimazono Susumu
Tokyo University
Cairo University
shiroi_kojika@hotmail.com
本研究テーマは「イスラム教．仏教における死後の世界」である。イスラム教ではどのよう
な見方や視点等から「死後の世界」がとらえられているかということについて深く研究しょ
うと思う。特に、エジプト人イスラム教徒研究者による「天国」および「自国」についての
研究や調査等を具体的に取り上げて考察したいと思う。その一方で、仏教、特に日本におけ
る仏教はどのように「死後の世界」をとらえているかという点についても調査しようと思う。
言い換えれば、具体的に日本の仏教思想における「自国」と「極楽」について本研究を進め
ていきたいと思う。最後に、本研究テーマについての両宗教における同類点も相違点も比較
的に明らかにした上で、果たして現代エジプト人イスラム教徒それから現代日本仏教徒はど
のような程度まで「死後の世界」についての教え等の影響を受けているかという疑問点で本
研究の結論を出そうと思う。
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EJISST-ID 318
日本語とアラビア語の慣用表現の意味と概念的メタファーのメカニズム
―生、死、時、喜、哀を中心に―
Almoamen Abdalla
Gakushuin University
Daito Bunka University
moamen_a@hotmail.com
慣用表現は私たちの日常生活の中に深く浸透している。また、慣用表現はレトリックの観点
から見ると、全般的に比喩性を持っていることは周知のことである。そのためかえって気づ
かずにいることがよくある。しかし、それらの表現は日常生活の中で、ごく当たり前のよう
に、自動的にそして多くは無意識に用いられるのは一体どうしてだろうか。
このことについて、ジョージ・レイコフとマーク・ターナー（1994）は次のように述べてい
る。「我々は人生を理解するための多くの基本的な隠喩を無意識的かつ自動的に習得してい
る・・・略」とある。つまり、メタファーの作用は、単なる言葉遣いの上だけの問題ではな
く、むしろ人間の認識や思考に宿った既成概念によるものであると考えた。
彼ら はこのよ うに思考の中に 存在 して いるメタファー を概念的 メタファー（ conceptual
metaphor）と呼んでいる。
本稿では、慣用表現の中に端的に見出される比喩（メタファー）の基本的メカニズムを探っ
ていく。慣用表現の比喩性を分析することによってその言語共同体がある事象、事柄をどの
ように捉えているのかなど、慣用表現の意味の成立を比喩の視点から調べてみたいと思う。
また、比喩といっても様々な種類があるが、この研究ではメタファーの視点から考察したい。
また、両言語の「生」「死」「時」「喜」「哀」に関する慣用表現では、メタファーが慣用
表現の意味形成において概念的にどのように作用しているか、またどのような解釈プロセス
を経て解されるかを整理・考察することを目的とする。さらに、「生」「死」「時」「喜」
「哀」の理解にあたっては、一連の概念的メタファーが存在することを前提に、両言語それ
ぞれの「生」「死」「時」「喜」「哀」に関する概念的メタファーの共通点と相違点を明ら
かにしようとする試みである。
EJISST2008 June 8~10
87
SESSION 8: Biotechnology - Agriculture - Food (2)
EJISST-ID 215
Microbiological, Chemical, sensory and shelf life evaluation of sliced
salmon treated with salts of organic acids
Khalid Ibrahim Sallam
National Institute of Advanced Industrial Sciences and Technology (AIST), Japan
Mansoura University, Egypt
khsallam@hotmail.com
This study was carried out to evaluate the shelf life, microbiological quality, chemical changes and
sensory attributes of fresh salmon slices treated by dipping in 2.5% (w/v) aqueous solution of sodium
acetate (NaA), sodium lactate (NaL), or sodium citrate (NaC) during refrigerated storage at 1 ºC. The
microbial results revealed that these salts were efficient (P < 0.05) against the proliferation of various
categories of spoilage microorganisms; including aerobic and psychrotrophic populations,
Pseudomonas spp., H2S-producing bacteria, lactic acid bacteria, and Enterobacteriaceae. The general
order of antibacterial activity of the different organic salts used was; sodium acetate > sodium lactate >
sodium citrate. The chemical analyses demonstrated significant reduction in K value, hypoxanthine
(Hx) concentration, total volatile base nitrogen (TVB-N), and trimethylamine (TMA) in treated salmon
slices when compared with the control. Lipid oxidation, as expressed by peroxide value (PV) and
thiobarbituric acid (TBA) value, was significantly (P < 0.05) delayed in NaA- and NaC-treated
samples. The antioxidant activity followed the order: NaC > NaA > NaL. Sensory scores of treated
salmon were in a typical category for appearance, juiciness and tenderness compared with the control.
Only minor changes in the sensory attributes were recognized by few panellists in NaA- and NaLtreated samples. A shelf life of 12, 12 and 15 days has been estimated for salmon treated with NaL,
NaC, and NaA, respectively, versus 8 days for control. Therefore, sodium acetate, sodium lactate, and
sodium citrate can be utilized as safe organic preservatives for fish under refrigerated storage.
EJISST-ID 228
Colistin susceptibility, pharmacokinetics, and residues in broilers and
laying hens
Waleed Fathy Khalil, Dalia H. Mansour and Shimoda Minoru
Tokyo University of Agriculture and Technology
Suez Canal University
wkhalil68@hotmail.com
One hundred and twenty four Escherichia coli isolates were obtained from autopsied chickens showing
lesions of avian colibacillosis in Egypt. Antibiograms showed that the majority of E. coli isolates were
highly susceptible to colistin sulphate (65.3%), neomycin (54.8%) and spiramycin (51.6%). Oppositely,
all isolates were resistant to oxytetracycline and amoxicillin (100% resistance). After single i.v. (1
mg/kg) or oral (25 mg/kg b.w.) administration of colistin sulphate to broiler and laying hens, colistin
could be detected in broiler plasma longer than in laying hen plasma. Following i.v. injection of colistin
sulphate, elimination half-lives (t0.5 β) showed no significant difference between broilers and laying
hens (1.82 and 2.61 hours, respectively). Total body clearances (Cltot) were 0.21 and 0.18 L/h.kg in
broiler and laying hens respectively. Areas under curves (AUC) were 2.93 and 2.75 μg/ml.h in broiler
and laying hens, respectively. After oral administration of colistin sulphate to broiler and laying hens,
absorption have-lives (t0.5 ab) and elimination half-lives (t0.5 β) were 0.60 and 0.41, 1.19 and 1.21 hours
respectively. Oral bioavailabilities (Foral) were 3.72 and 2.60% in broiler and laying hens respectively.
No detectable levels of colistin could be measured in muscles or egg after single oral administration of
colistin.
EJISST2008 June 8~10
88
EJISST-ID 237
Implementation Degree of Agricultural Decisions in the farm Level:
Comparison Study between Egypt and Japan
Adel I. Ali and Teuraki Nanseki
Kyushu University, Japan
KafrElsheikh University, Egypt
a_elhamoly@yahoo.com
This research will describe the degree of implementing some agricultural decisions (IAD) in the farm
level in Egypt and Japan. The Egyptian data in this research was derived from systematic random
sample of 335 farmers from graduates areas, El-Hamoul district, Kafr El-Sheikh governorate. The
statistical methods for data analysis included: frequencies, percentage, mean, standard deviation, t-test
and LSD (least of significant differences). Results of Egyptian sample indicated that: 55%of farmers
implemented their agricultural decisions and continued the implementation, 11% implemented their
agric. decisions but they stopped implementation. Also, 34% of farmers can not implement these
decisions in their farms. The farmers declared that the main reasons for not implementing agric.
decision were: unavailability of manufacture (100%),unavailability of supervision on the
implementation (95.5%), low of the available facilities (92%), unavailability of industrial crops(91%),
and training centers so far from farmers villages(85%).The Egyptian data showed also that the most
important agric. information sources were the family(89.3%), friends (80%), neighbors(70.4%), agric.
society director (67.2%) and agric. requirements shops & companies (60.3%).In addition,58% of
farmers declared that they wasn’t have any agric. services centers in their areas . The Egyptian data
declared that 21.5% of the farmer’s have a low degree of implementing their agricultural decisions, and
62.4% of them have moderate implementation degree, and finally 16.1% of them have high
implementation degree to their agric. decisions.
EJISST-ID 263
EVALUATION OF NATURAL ANTIOXIDANTS EXTRACTED FROM
DIFFERENT AGRO-INDUSTRIAL BY PRODUCTS
Sahar R. Abd El-Hady and Tashiro Matsui
Kyushu University
Kafr EL-Sheikh University
saharabdelhady@yahoo.com
This investigation was carried out to study the possibility of extraction of some natural antioxidative
phenolic compounds from some agro-industrial by products (defatted black and white rice brans, sweet
potato peels and potato peels). The extracted phenolic compounds were tested as natural antioxidants
using cotton seed oil comparing with synthetic antioxidants butylated hydroxytoluene (BHT) after deep
frying of potato for 25 hours. In this respect, the polyphenols were extracted from Agro-industrial by
products using several solvents. The chemical composition of the total polyphenolic compounds was
characterized by high performance liquid chromatography (HPLC) method. The oxidative rancidity of
cotton seed oil containing various concentration of polyphenols (100, 200 and 400 part per mellion
(ppm)) was followed by rancimate method. Another set of nutritional experiemtns were performned to
elucidate the extent at which the polyphenols are safe for human being. Several solvents (chloroform,
Acetone, methanol and ethanol) were used to extract the natural antioxidants from different agroindustrial by products (defatted black and white rice brans, sweet potato and potato peels. The results
indicated that methanol was the best solvent for extracting polyphenols compound. However, amount
of polyphenolic compounds were as follow: 1050.12, 890.15, 930.50 and 680.25 (ppm) from defatted
black rice bran, defatted white rice bran, sweet potato peels and potato peels respectively. HPLC
analysis for the total polyphenmols extracted from the Agro-industrial by products indicated to
presence of chlorogenic, caffeic, ferulic, elagic protocatechuic and vanillic acid. The total polyphenols
extracted at 400 ppm possessed superior antioxidant effect.
EJISST2008 June 8~10
89
EJISST-ID 213
Regulation of developmental timing by transcription factors in
Drosophila melanogaste
Moustafa Mohamed Hemida Sarhan and Ueda Hitoshi
Okayama University
Alazahr University
moustafar@yahoo.com
During animal development, regulatory processes must be properly timed so that cell growth and
differentiation are appropriate for the particular life stage of the animal. In insects including Drosophila
melanogaster developmental transitions occur at regularly defined intervals. These transitions include
metamorphosis, a stunning transformation in which the immature larva changes into the reproductively
mature adult. These changes are mediated to a large extent by small circulating steroid hormones that
bind and activate transcription factors of the nuclear receptor superfamily. Although the genetic
hierarchy that controls responses to 20E has received considerable attention, little is presently known
about the regulatory mechanisms that control the timing of these responses during development. We
are interested in elucidating the mechanisms that regulate the ftz-f1 gene expression as a means of
gaining insight into the issue of developmental timing. We focused our attention on its promoter region
and dissected it to identify new factors which can bind to this region. We have identified dBlimp-1 as a
new transcription factor induced directly by 20E and works as a repressor for the ftz-f1 gene. Our longrange plans include a study to show that dBlimp-1 is a timer protein which can determine the precise
timing for prepupal to pupal transition. These studies should enable us to learn more about how key
cellular and morphological changes are programmed to occur at appropriate times during development.
In addition, since all insects are supposed to require the ftz-f1 gene for normal development, these
studies may provide targets for the development of novel agents to control insect populations that have
both agricultural and biomedical impact.
EJISST-ID 196
A 450-kb B chromosome in a filamentous ascomycete Nectria
haematococca mating population I (anamoph, Fusarium solani f. sp.
cucurbitae)
Ahmed Mohamed Mahmoud and Masatoki Taga
Okayama University
Alazhar University
amkasem@yahoo.com
Pulsed field gel electrophoresis and Southern blotting analysis on N. haematococca mating population I
(MPI) showed that a certain strain has a ca. 450-kb extra DNA band with TTAGGG telomere
sequences in its genome. Subsequent cytological observation on mitotic metaphase revealed this DNA
band to represent a minute B chromosome of almost 0.4-0.6μm in length and occur as a single copy in
the genomes of somatic nuclei. Chromosome painting FISH using total DNA of 450-kb band as probe
suggested that this chromosome was not the derivative of A chromosomes. In the crossing experiments
performed between the strain harboring that chromosome and another strain without any B
chromosomes, tetrad and random ascospore analyses showed that this chromosome was transmitted to
the progenies through meiosis in a regular Mendelian manner, which seems peculiar compared with
other B chromosomes found in different organisms. Because of its small size, this 450-kb B
chromosome is though to be easy to manipulate with genetic engineering techniques, and therefore,
may be a promising candidate for constructing artificial chromosome in filamentous fungi.
EJISST2008 June 8~10
90
EJISST-ID 226
Expression and functions of retinol binding protein 4 in bovine
adipocytes
Mabrouk A. Abd Eldaim and Kazuhiro Kimur
Hokkaido University, Japan
Menofiua University, Egypt
mabroukatia@yahoo.com
Retinol binding protein 4 (RBP4) is a plasma protein that transports retinol; know as vitamin A, to
support a variety of physiological functions such as vision. In addition, retinol is known to suppress
adipogenic differentiation and affect meat quality like the degree of marbling. However, expression and
functions of RBP 4 in bovine adipocytes remains to be elucidated. First, we examined localization of
RBP4 mRNA in the tissues from Holstein cows. RT-PCR analysis revealed that RBP4 mRNA
expressed richly in the liver and adipose tissue, and also lung to a lesser extent, but not in kidney, heart,
spleen and skeletal muscle, in accordance with the RBP4 expression in other species. To examine the
regulatory mechanisms of RBP4 expression in bovine adipose tissue, stromal vascular fractions were
prepared from Holstein subcutaneous adipose tissue and from subcutaneous and intramuscular adipose
tissues of Japanese black steers (J.S.C.& J.I.M.). These cells were cultured separately with or without
inducing adipogenic differentiation, and the degree of the differentiation was confirmed by
accumulation of triglyceride and expression of adipocyte-type of fatty acid binding protein (aP2) gene.
Northern blot analysis showed that the cells before and after the induction of adipogenic differentiation
expressed RBP4 and s J.I.M. preadipocytes expressed RBP4 higher than J.S.C preadipocytes. In
addition western blot analysis reveled that both preadipocytes and mature adipocytes secrete RBP4 into
the medium and J.I.M. preadipocytes secreted RBP4 higher than mature J.I.M. adipocytes. The
additional studies are ongoing to reveal the expression and functions of RBP4 in bovine adipocytes.
EJISST-ID 178
New Selective cytotoxic compounds from zizyphus spina christi L
Mahmoud Abdalla, Fumihide Takano and Tomihisa Ohta
Kanazawa University, Japan
Al-Azhar University, Egypt
mahmcognosy@yahoo.com
There is increasing evidence that certain natural compounds found in plant may be useful as cancer
chemotherapeutics agent. In our search for selective antitumor compounds from indigenous Egyptian
plant species, there are several studies indicated that betulinic acid (triterpene) present in Zizyphus
species is a selective inhibitor of human melanoma, malignant brain tumors and ovarian carcinoma.
Thus, the purpose of this study was to search for new selective cytotoxic compounds from Zizyphus
spina Christi L. The bioassay-guided fractionation of the methanolic extract of zizyphus spina christi
leaves led to isolation of two new cytotoxic compounds, Lupan-4-ol-28-oic-2,3-epoxytriterpene (1) and
3-O-[β-D-glucopyranosyl(1-3)-α-L-arabinopyranosyl]-20-O-α-L-rhamnopyranosyljujubogenin
(2).
Their structures were acomplished by extensive spectroscopic methods including application of 1D
(1H, 13C, 13C Dept), 2D NMR expermints (HMQC, HMBC, COSY) and HRESIMS analysis. Their
cytotoxic acivity were evaluated against two types of tumor cell line, HeLa cell and THP1. At the same
concentrations, normal bone marrow cells were unaffected indicating a selective effect of these
compounds.
EJISST2008 June 8~10
91
EJISST-ID 231
Bio-surface modification of some oxide minerals and its application in
minerals separation
Mohsen Mohammad Farahat and Tsuyoshi Hirajima
Kyushu University, Japan
CMRDI, Egypt
mohsen_farhat@yahoo.com
Adsorption experiments of SIP (Silica Induced Protein) E. coli bacterium on quartz and hematite
minerals were conducted. The results showed that, the number of adsorbed cells is high at acidic pH
and gradually decreases with increasing pH to the neutral and the alkaline regions for both minerals.
The Interaction between SIP E. coli bacterium and minerals resulted in a significant change on the
surface chemistry of minerals especially for quartz where, after such treatment, the IEP (Iso Electric
Point) for quartz was shifted from pH <2 to pH 4.3 and quartz particles rendered relatively more
hydrophobic properties. SIP E. coli was found to be acting as a collector for quartz since about 80% of
quartz could be floated using bacterium only without any other reagents at low pH. The interaction of
SIP E. coli with hematite minerals does not affect on its floatability. Using SIP E. coli, it was possible
to separate quartz from hematite-quartz mixture with Newton’s efficiency 0.7 and the grade of hematite
increased from 48% to 80 % with 88% recovery.
EJISST-ID 072
Biotechnological studies on halophilic bacteria isolated from Egyptian
salt lakes
Omneya Abd El Hafez and Shinichi Nagata
Kobe University
Alexandria University
omneya_ahmed@yahoo.com
A group of halophilic strains were isolated from solar saltern lakes in Alexandria city, Egypt. One of
the isolated strains, strain EG6 was identified by 16S rDNA gene sequencing as a member of the genus
Halomonas. Strain EG6 produced ectoine as the main compatible solute for osmotic stress adaptation
and we subjected strain EG6 to osmotic downshock treatment from 2 M to 0-0.7 M to determine how
much NaCl concentration is optimum for the highest total yield of ectoine. Strain EG6 was able to
compensate the loss of ectoine during osmotic downshock with high efficiency and the highest yield of
ectoine, 3.7 g/L, was totally released after 7 days of osmotic downshock from 2 M to 0.3 M NaCl.
From this data, we can conclude that strain EG6 is a good source for high yield of ectoine. Further
work is needed to investigate strain EG6 new characters. Another part of my study is a survey of heavy
metal tolerance of halophilic strains and its relation to the existence of plasmid. 24 halophilic strains
were grown in the presence of different concentrations of toxic metals such as Zn2+, Pb2+, Cu2+, Co2+,
Ag+, Ni2+, AsO43-, Hg2+ and CrO42- to determine the minimum inhibitory concentration of growth
(MIC). Those strains showed different heavy metal resistant ability as most of them can grow up to100
mM of Na2HAsO4 and 1-2 mM or up to 9 mM of the other tested metal ions. Eleven strains harbored
plasmid of different size which might be correlated to heavy metal tolerance. Further work is needed to
clarify the mechanism of heavy metal tolerance and identify strains with high tolerance ability which
can be used for bioremediation of pollutant areas.
EJISST2008 June 8~10
92
EJISST-ID 208
Effect of high temperature on sex differentiation and germ cell
population in medaka, Oryzias latipes
Khaled M. Selim, Ai Shinomiya, Hiroyuki Otake, Satoshi Hamaguchi and Mitsuru Sakaizumi
Niigata University, Japan
Zagazig University, Egypt
khaledselim2000@yahoo.com
Medaka, Oryzias latipes, has an XX/XY sex determination sysytem with DMY as the sex determining
gene. Previous studies confirmed that the process of sex determination in medaka is sensitive to the
effects of high temperature. In this study fertilized eggs of two inbred strains were divided into four
groups, two of them exposed to 27 and 32 + 0.2◦C and others were shifted reciprocally between 32 and
27◦C at stage 25 until hatching to examine sex ratio as well as gonadal development. XX sex reversal
ratio in Hd-rR and HNI was 17.2 and 54.2% at 32◦C, and 3.8 and 66.7% in the shifted group from 27 to
32◦C, respectively. While incubation at 27◦C and shifted from 32 to 27◦C resulted in no sex reversals in
Hd-rR, it resulted in 10 and 29.9% sex reversal in HNI. This result showed that the sensitive period of
sex reversal was mainly after stage 25 although the effects of the exposure during earlier stages could
not be neglected. The sex reversal ratio in GFP transgenic fish was similar to that in Hd-rR. In this
strain gonadal sex reversal was detected at the time of hatching, which was judged by the absence of
both leucophores on the body surface and the GFP signals in the gonad. Fish with GFP signals at 0 dah
developed ovary in elder stages. High temperature had a clear effect on XX fish with unmarked effect
on XY fish. In treated groups of Hd-rR at 32◦C, some XX fish at 0, 5 and 10 dah had very low number
of gonia cell similar to normal XY fish; others showed lower number of germ cell with little effect on
germ cell population as well as some fish not affected. In HNI, in which the number of germ cell was
more numerous and variable at hatching, developing oocytes appeared earlier and effect of high
temperature was clearer than Hd-rR. These data suggested that high temperature leads to inhibition of
proliferation of germ cells and development of oocytes, and then induced gonadal and phenotypic sex
reversal.
EJISST-ID 264
Immunohistochemical investigation for arthropod brain design and the
functional relationship to the mid gut system
Maged Fouda
Kobe University
Al-Azhar University
aaaamaged2000@yahoo.com.sg
Feeding behavior is regulated not only by the CNS but also by the peripheral tissues including positive
and negative sensory feed back, local hormonal regulation, gastric and intestinal digestion, and the
effect of nutrients. In mammals, several neuropeptides such as cholecystokinin, orexin and
neuropeptide Y are involved in the regulation of feeding behavior. These neuropeptides are produced in
gut endocrine cells as well as in the nervous system. However, molecular and/or functional aspects of
midgut neuropeptides have not been well characterized.Crustacean cardioactive peptide (CCAP) is an
unusual cyclic nonapeptide and its sequence does not resemble that of any other known neuropeptide.
CCAP has Multifunction in regulation of gut tissue as both a neuropeptide and novel midgut factor for
the following lines of evidences. It leads to increase in α-amylase and protease activity in mid gut; it
regulates the activity of digestive enzymes, responsible for regulation of digestion of proteins as well
starch; it acts centrally as proximal trigger of ecdysis behavior at the larval pupal molt in M. sexta. We
employed various arthropods including crustaceans, insects and spiders to investigate arthropod brain
design and the functional relationship to the mid gut system. Our results indicated that CCAP
immunoreactivity was confined to a strong band at a position of about 12.2 kDa and a weak band at
about 6.0 kDa in spider, Nephila clavata and a strong band of about 10.0 KDa and a weak band about
EJISST2008 June 8~10
93
6.0 KDa in isopoda, Armadillidium vulgare. Furthermore we recently succeeded to clone a partial
sequence of CCAP from isopoda, A. vulgare. Interestingly, it shows about 100% similarity at amino
acid level with that of insect CCAP cloned from Periplaneta Americana. On the other hand, by using
immunohistochemistry techniques we detected CCAP signals in isopod and spider brain. The complete
investigation of arthropod brain design and the functional relationship to the mid gut system are now
under way.
EJISST-ID 265
Characterization of a novel dehalogenase involved in 2-chloroacrylic
acid metabolism in Pseudomonas sp. YL
Amr Mohammed Hassan and ESAKI, Nobuyoshi
Kyoto university
Mansoura University
drammr79@yahoo.com
Various microorganisms are known to produce dehalogenases that detoxify halogenated organic
compounds by cleaving carbon-halogen bonds. These enzymes are attracting a great deal of attention
from the viewpoint of environmental technology. Dehalogenases are also useful for stereospecific or
regiospecific conversion of halogenated compounds into valuable compounds. There is a broad range
of dehalogenases which can be classified in different protein superfamilies and have fundamentally
different catalytic mechanisms. In this study we report the presence of a novel dehalogenase in 2chloroacrylic acid (2-CAA) utilizable bacterium Pseudomonas sp. YL. This enzyme named CAA67 YL
is inducibly synthesized in the presence of 2-CAA as a sole carbon source in the growth medium.
CAA67 YL gene was cloned and shown to encode 547 amino acid residues (Mr 59,301), which shared
a high sequence similarity with another 2-CAA inducible protein from Burkholderia sp. WS. Both of
them have a weak but significant sequence similarity with L-aspartate oxidase from Escherchia coli and
fumarate reductase (subunit A) from Wolinella succinogenes. CAA67 YL was overproduced in E. coli.
This protein was suggested to catalyze the FADH2 dependant dehalogenation of 2-CAA.
EJISST-ID 280
Establishment of regeneration and transformation protocol for
Anthurium andreaum
Nader ahmed mohmed darwish and Masahiro Mii
Chiba university
Alexandria university
drnader_darwish@yahoo.com
To establish an effective technique to regenerate an in vitro plant for anthurium andreaum, cvs Vivaro,
Pink champion and White champion ( Dutch cultivars) .leaf, spathe, flowering stalk and leaf petiole
were cultured on MS medium and modified MS medium supplemented with of 0.1- 0.2 mg/l 2,4 -D
and 1- 2 mg/l BA . Results showed that the best concentration is 0.2 mg/l 2, 4-D with 2 mg/l BA for
MS medium and 0.1 mg /l 2,4-D and 1mg/l BA for modified MS medium. The four different tested
explants induced callus within 30-40 days in case of MS medium and 21-30 days in case of the
modified one. Pink champion showed the highest response to the culture, fowled by Vivaro and White
champion. Callus proliferation, formation of shoots and roots are still under the observation.
Anatomical studies showed the organogenic nature of these calli.
EJISST2008 June 8~10
94
EJISST-ID 282
Development of live attenuated vaccine for Edwardsiella tarda infection
in fish
Alkhateib Y. Gaafar and Toshihiro Nakai
Hiroshima University, Japan
National Research Center, Egypt
alkhateibyg@yahoo.com
Edwardsiella tarda is the causative agent of a septicemic disease known as edwardsiellosis. E. tarda
affects a wide range of host including birds, reptiles, amphibians and animals as well as humans.
Edwardsiellosis represents a great threat to aquaculture including freshwater and saltwater fish
worldwide. Some virulence factors of this pathogen have been proposed. However, their exact role in
pathogenesis is still vague. Several trials for developing a vaccine to control the disease have been
conducted; but no widely accepted commercial vaccine is available so far. The current work was
directed to investigate the use of some mutants as live vaccine against E. tarda infection.
EJISST-ID 300
Microbiological Quality of Some Egyptian Meat Products
Mahmoud Mohammed, Takeshi Honda and Mohammed Elgazzar
Osaka University
Mansoura University
mahmoudmahros@yahoo.com
As a task of our Meat Hygiene concerning about the microbiological quality of meat and meat
products, a total of 60 samples of meat products collected from different localities in Mansoura city,
were subjected to the microbiological analysis. The total bacterial counts of aerobic mesophiles,
Enterobacteriaceae, Staphylococcus aureus "coagulase-positives" and Bacillus cereus were ranged
from 1x105 to 5x109, 5x102 to 2.6x106, 1x102 to 6x105 and 6x102 to 3x107 per each gram of the
examined samples, respectively. However accurate identification of bacterial isolates is an essential
task in food microbiology, 16S rRNA (PCR amplification and sequencing) sequencing is a recent
method of identification which offers a useful alternative. Bacterial 16S rRNA genes generally contain
nine “hypervariable regions” that demonstrate considerable sequence diversity among different
bacterial species and can be used for species identification. In this study, we investigated the usefulness
of this method for identifying a range of bacteria. Using 16S rRNA sequencing we could identify
Enterobacter sakazakii which considered as an emerging pathogen involved in several foodborne
outbreaks of meningitis and enterocolitis in neonates. This is the first study could identify this species
in Egypt and also from different meat products.
EJISST2008 June 8~10
95
SESSION 9: Biotechnology - Medicine (2)
EJISST-ID 248
Gene Expression Profiles in High and Low Metastatic Potential Lung
Cancer Cell Lines, a cDNA Microarray-Based Study
Ashraf A. Ewis,1,5,6 Kazuya Kondo,2 Yasuo Shinohara,3 Mitsuru Ishikawa,1 Yoshinobu
Baba,1,4 and Yutaka Nakahori1
1
Department of Clinical Genetics, Institute of Health Bioscience, The University of Tokushima, Japan
2
Department of 2nd Surgery, Institute of Health Biosciences, The University of Tokushima, Japan
3
Division of Gene Expression, Institute for Genome Research, The University of Tokushima, Japan
4
Department of Applied Chemistry, Graduate School of Engineering, Nagoya University, Japan
5
Health Technology Research Center, National Institute of Advanced Industrial Science and
Technology (AIST), Japan
6
Department of Occupational Medicine, Faculty of Medicine, El-Minia University, Egypt
Lung cancer is the most common cancer in terms of both incidence and mortality with 1.3 million new
cases diagnosed per year and 1.18 million deaths, annually. The prognosis of lung cancer is still
generally poor, worldwide. The prognostic factors of lung cancer include the presence or absence of
symptoms, tumor size, histopathological type of cells, stage, metastasis to multiple lymph nodes, and
vascular invasion. The genetic backgrounds of lung cancers with different cellular behaviors have not
been well-characterized and the global gene expression profiles of lung cancer cells with different
metastatic potential have not yet been thoroughly investigated. Recently, great progress has been made
in techniques for comparing differentially expressed genes, i.e. differential display PCR, serial analysis
of gene expression (SAGE), and microarrays. Above all, the development of the high-density cDNA or
oligonucleotide microarrays has been introduced to the research fields as a powerful tool that allows
studying and monitoring gene expression profile for thousands of genes, simultaneously. Researchers
have used the microarray technology to study cancer genetics trying to understand the mechanisms of
cancer initiation and progression. Experimental designs usually depend on comparing the mRNA
derived from cancer tissues and compare it with the mRNA of normal tissues. Of course this approach
is very useful especially when the study considers the characteristics of the tumor tissues under study
i.e. grade, stage, clinical symptoms and signs, metastatic and prognostic issues. In this study, we
established two lung cancer cell lines with different metastatic potential. We depicted them as: a high
metastatic and a low metastatic lung cancer cell lines. Then we studied the characteristics and gene
expression profiles of both cell lines in order to find the genetic backgrounds that govern the
proliferation of the high metastatic cells and stimulate their aggressive behavior with high and early
metastatic potential. Here, we report on a global analysis of the gene expression in the two established
high and low metastatic lung cancer cell lines, using a cDNA microarray to characterize the genetic
expression alterations that favors early and high metastatic behavior leading to poor prognosis and
eventual mortality.
EJISST2008 June 8~10
96
EJISST-ID 260
An efficient in-vitro model for the study of natural Hepatitis C virus
infection
Hussein Hassan Aly and Makoto Hijikata
Kyoto University
National Association for teaching hospitals
hussein@genome.med.kyoto-u.ac.jp
Background/Aims: The developing of an efficient in-vitro infection system for HCV is important in
order to develop new anti-HCV strategy. Only Huh7 hepatocytes cell lines were shown to be infected
with JFH-1 fulminant HCV-2a strain and its chimeras. Here we aimed to establish a primary hepatocyte
cell line that could be infected by HCV particles from patients’ sera. Methods: We transduced primary
human hepatocytes with human telomerase reverse transcriptase together with human papilloma virus
18/ E6E7 (HPV18/E6E7) genes or simian virus large T gene (SV40 T) to immortalize cells. We also
established the HPV18/E6E7-immortalized hepatocytes in which interferon regulatory factor-7 was
inactivated. Finally we analyzed HCV infectivity in these cells. Results: Even after prolonged culture
HPV18/E6E7-immortalized hepatocytes exhibited hepatocyte functions and marker expression and
were more prone to HCV infection than SV40 T-immortalized hepatocytes. The susceptibility of
HPV18/E6E7-immortalized hepatocytes to HCV infection was further improved, in particular, by
impairing signaling through interferon regulatory factor-7 or by improving the hepatocytes
differentiation through 3 dimensional culture.. Conclusions: HPV18/E6E7-immortalized hepatocytes
are useful for the analysis of HCV infection, anti-HCV innate immune response, and screening of
antiviral agents with a variety of HCV strains.
EJISST-ID 182
Increased Intestinal Endotoxin Absorption during Enteric Nematode but
not Protozoal Infections through a Mast Cell-Mediated Mechanism
Ayman Samir Farid and Yoichiro Horii
University of Miyazaki, Japan
Benha University, Egypt
aymansf@yahoo.com
It is known that hypersensitivity reactions in the gastrointestinal tract, which are primarily mediated by
mast cells, are associated with a secretory response of the epithelium and often increased permeability
to macromolecules. Studies to date have not examined the effects of hyperpermeability on the
absorption of toxic substances normally present in the intestinal lumen such as bacterial
lipopolysaccharides (LPS). In the present study, we observed that Strongyloides venezuelensis infection
in mice decreases the mRNA expression of intestinal epithelial cell junctional molecules (occludin and
zonula occludens 1) and increases portal endotoxin levels 4 hours after intragastric administration of
LPS (20 mg/kg body weight). Furthermore, an increase in the flux of immunoglobulin G into the
intestinal lumen was observed 10 days postinfection (PI). An increased rate of LPS absorption was also
seen in mice infected with Nippostrongylus brasiliensis on day 14 PI and rats concurrently infected
with S. venezuelensis and N. brasiliensis on day 20 PI. On the other hand, infection with Eimeria
vermiformis and Eimeria pragensis was not observed to enhance LPS absorption 4 h after intragastric
administration of LPS (20 mg/kg body weight), although E. vermiformis infection did inhibit the
epithelial cell mRNA expression of zonula occludens 1, but not occludin, on day 9 PI, resulting in a
reduced immunoglobulin G flux than that produced by S. venezuelensis infection. Our results suggest
that mastocytosis accompanying intestinal nematode infection increases the intestinal absorption of
LPS into the portal circulation by suppressing the expression of tight junction molecules.
EJISST2008 June 8~10
97
EJISST-ID 257
The role of membrane type1- matrix metalloproteinase ( MT1-MMP) in
cancer ivasion and metastasis
Moustafa sakr and Hiroshi Sato
Kanazawa University
Menofiya University
dr_sakr2000@yahoo.com
Matrix metalloproteinases (MMPs) are a class of enzymes that play an important role in the remodeling
of the extracellular matrix in development and cancer metastasis. Among the MMP, membrane type 1
matrix metalloproteinase (MT1-MMP), MMP-2, MMP-7 and MMP-9 have been reported to be most
closely associated with tumor invasion and metastasis. MT1-MMP is an integral membrane protein that
participates in the processing and degradation of cell surface proteins and the extracellular matrix
(ECM). This enzyme regulates ECM turnover in wound repair, promotes cell migration and activates
other MMPs, such as MMP-2, which is involved in angiogenesis, cell migration and tumoral
metastasis. This work aims to study two points: Cloning of ECM and/or non-ECM Substrates of MT1MMP, in principal, and/or other MMPs, and Clarifying the physiological significance of the bio-talk
between a cloned candidate and MMPs, especially MT1-MMP. In this study we have used an
expression cloning strategy to screen for gene products that modulate the activation of MMP-2 by
MT1-MMP. Until now we have cloned several candidate genes, the products of which either positively
or negatively regulate processing of pro-MMP-2 mediated by MT1-MMP, and now we try to explain
the way which these genes or gene products are acting or affecting MT1-MMP in terms of finding
potential therapeutic targets, into prevention of cancer invasion and metastasis
EJISST-ID 277
Chk1 is a histone H3-T11 kinase that regulates DNA damage-induced
transcriptional repression
Doaa Hussein Zineldeen and Makoto Nakanishi
Nagoya City University
Tanta University
zineldeen@gmail.com
In eukaryotes, DNA damage alters the global pattern of gene expressions to orchestrate at variety of
cellular events including growth arrest, apoptosis, and DNA repair. Following UV-induced DNA
damage ~4 % of transcripts showed >3 fold-changes. Approximately 90% represented downregulation. Transcriptional activation has been well characterized in the context of sequence-specific
DNA-bound activators, whereas mechanisms of transcriptional suppression are largely unexplored. We
show here that DNA damage rapidly reduced histone H3-T11 phosphorylation. This correlated with
repression of several hundred genes, including Cyclin B1 and cdk1. H3-T11 phosphorylation occurs
throughout the cell cycle and is Chk1-dependent in vivo. To establish the extent of Chk1-dependent
transcriptional maintenance, we conducted microarray experiments to investigate the global
requirement for Chk1 in gene expression. We observed that 214 transcripts were down regulated
following Chk1 depletion. Thus, Chk1 is required for the correct expression of many genes in vivo.
Some of these genes was selected three genes, and confirmed that their expression was repressed in
response to DNA damage, further linking the function of Chk1 to DNA damage-induced transcriptional
repression. Following DNA damage, Chk1 undergoes rapid chromatin dissociation, concomitant with
reduced H3-T11 phosphorylation. ChIP analysis of Cyclin B1 and CDK1 promoters demonstrates that
loss of H3-T11 phosphorylation correlates with loss of GCN5 binding, and reduced H3-K9 acetylation.
In vitro, GCN5 has a 20-fold higher affinity for H3-pT11 peptide compared to non-phosphoyrlated
peptide. Our results suggest a mechanism by which Chk1 acts as a histone kinase responsible for DNA
damage-induced transcriptional repression by loss of histone acetylation.
EJISST2008 June 8~10
98
EJISST-ID 278
Virological and clinical implication of core promoter C1752/V1753 and
T1764/G1766 mutations in hepatitis B virus genotype D infection
Abeer Abd elRaheem Ahmed and Masashi Mizokami
Nagoya City University
Sohag University
abeerelkady@hotmail.com
Background and Aim: The aim of this study was to reveal virological and clinical features of hepatitis
B virus genotype D infection. Methods: 122 Mongolian, chronic liver diseases (CLD) patients infected
with HBV were subjected for serological HBV-markers’ screening and HBV-EIA genotyping.
Nucleotide sequences were analyzed for 48 HBV/D strains (23 isolated from hepatocellular carcinoma
(HCC) and 25 from CLD patients). Results: Prevalence of HBeAg positivity was low (25.9%) in young
patients (<30 years-old) indicating early HBeAg seroclearance in HBV/D carriers. The T1764/G1766
double mutation was most common basal core promoter (BCP) mutation (29.2%) and was frequent in
HBeAg-negative patients (39.3%). Patients harboring T1764/G1766 mutants exhibited lower HBV
DNA and HBV core antigen (HBcAg) levels than those with wild BCP strains (P= 0.024, 0.049
respectively). C1752 and/or V (not T) 1753 mutation was significantly prevalent in HCC patients
(HCC vs. CLD; 52.2% vs. 20%, P=0.033). T1762/A1764 mutation was detected in 75.0% of HCC
patients with high viral load (≥5 log copies/ml). Precore stop codon mutation A1896 was detected in
(70.8%) of HBV/D infected patients. Conclusions: In Mongolians infected with HBV/D, C1752 and/or
V1753 mutation was associated with HCC.
EJISST-ID 284
Facial Nerve Injury induces activation of NF-kB in rat facial nucleus
Majid Mohamed Safwat Hafez and Shingo Murakami
Nagoya City University
Cairo University
Majidsafwat@gmail.com
Nerve injury leads to induction of a large number of genes to repair the damage and to restore synaptic
transmission. NF-kB is a transcription factor involved in physiological and pathological processes such
as; neuronal survival, cellular growth, inflammation and apoptosis. Previous studies on the rat sciatic
nerve reports increased activity of NF-kB in dorsal root ganglion after complete transection and
ligation of sciatic nerve. Here we investigated the effect of different types of facial nerve injuries
including complete facial nerve transection (CFNT) and facial nerve compression (FNC) for 30
seconds using mosquito to ensure transient facial nerve palsy together with Sham operated control, on
the activity of NF-kB in rat facial nucleus, starting immediately after injury and throughout one month
using immunohistochemistry. We concluded that NF-kB activity is upregulated at the facial nucleus
following facial nerve injury being higher in (FNC) than in (CFNT). These findings highlight the role
of NF-kB as a novel target in promoting facial nerve healing after injury.
EJISST2008 June 8~10
99
EJISST-ID 294
Effect of two housing systems and stocking density on White New
Zealand Rabbit
TAREK M. M. BALABEL
Tottori University
Kafr El-Sheikh University
balabel_2006@yahoo.com
This work was carried out to study the effect of two housing systems and stocking density on White
New Zealand rabbit welfare and productivity. In this study we used 62 recently weaned does of average
body weight (600) grams. Those rabbits were divided into 6 groups according to stocking density ( 2,
4, 8, 12, 16, 20). Each group was divided into two equal subgroups; the first subgroup was reared in
pen and the second one was reared in cage. They fed a commercial pelleted diet of 16.5% crude
protein, 2.5% crude fat and 14% fibers. The diet was offered twice daily at 9 a.m. and 5 p.m. with
adlibitum amount and provided with the drinking water. All rabbits were allowed one week to become
accustomed to their new cages. The individual body weight at the beginning and end of experiment and
amount of food and water were recorded daily. As well as, feed conversion ratio and some behaviours
(maintenance, locomotor, agonistic, comfortable and stereotypic). The observed data revealed that in
most cases caged and penned rabbits showed different average percentages of behaviours. Also,
different stocking densities revealed variable percentage of recorded behaviours. It can be concluded
that the rearing rabbits in pen more welfarable than cage and it’s better from behavioural view to use
stocking density under six rabbits in one place with each other.
EJISST-ID 290
Treatment of scaphoid nonunion with dorsal transplantation of
vascularized bone grafts
Ahmed Naeem Atiyya and Ryosuke Kakinoki
Kyoto University
Ain Shams University
anatiyya@yahoo.com
Background: Scaphoid nonunions remain challenging problems in the wrist surgery. Vascularized bone
transplantation is an attractive solution of the scaphoid nonunion because it provides viable bone and
intrinsic vascularity. We assessed the union rate and functional outcome of scaphoid nonunions treated
by dorsal transplantation of vascularized bone grafts taken from the distal dorsal radius to the site of the
nonunions. Methods: Fifteen consecutive patients with scaphoid nonunions were operated on between
February 2003 and August 2007. The mean interval between the initial injuries and the procedures was
60 months. Pedicled grafts based on 1,2 intercompartmental supraretinacular artery were transplanted
as inlay grafts to 8 cases without the DISI deformity. In the remaining 7 cases with the DISI deformity,
correction of the deformity was followed by transplantation of the vascularized grafts in an
interposition fashion to the trapezoidal scaphoid bone defects created at the scaphoid nonunions
through an all-dorsal approach. Results: Union was accomplished in all cases in an average of 11.53
weeks (range 8-30 weeks). Although the palmar flexion and ulnar deviation significantly decreased
postoperatively, functional results as reflected by modified Mayo wrist score and modified
Wrightington Hospital wrist scoring system were improved. The radiolunate angles significantly
improved from -12.07° ± 13.54º preoperatively to 0° ± 8º postoperatively. Conclusion: Vascularized
bone grafts transplanted to scaphoid nonunions dorsally corrected the DISI deformity and augmented
the vascularity of the proximal scaphoid.
EJISST2008 June 8~10
100
EJISST-ID 305
Comparative Study between Open and Laparoscopic Distal
Pancreatectomy
Mohammed Yahia Farrag and Shuji Shimizu
Kyushu University
Assiut University
mohamad_yf@yahoo.com
Although minimally invasive surgery has achieved worldwide acceptance in various fields,
laparoscopic surgery for pancreatic diseases has been reported only rarely. Laparoscopic distal
pancreatic resection has increasingly been described as a feasible and safe procedure, although
accompanied by a high rate of conversion and morbidity. For that reason we are doing our study to
compare between the conventional open technique in distal pancreatectomy and the newly developing
laparoscopic technique as regard to feasibility, safety and clinical outcomes. All patients presented to
Kyushu University Hospital for distal pancreatectomy due to pancreatic tail lesions are included in our
study (retrospective study). The patients are separated into two groups; open group and laparoscopic
group. The site of the lesion is determined prior to surgery by various radiological measures. Routine
check for amylase in the drain postoperatively is performed for diagnosis of pancreatic fistula.
Comparison is made between the two groups as regard to operative time, operative blood loss, intra and
postoperative morbidity and mortality, splenectomy (done or not), resection measure (automatic suture
device used or not), hospital stay, hospital charges, and prognosis.
EJISST-ID 306
Caspase activation role in the antiviral treatment response in chronic
hepatitis C virus infection
Walaa Hassan, Norihiro Furusyo and Jun Hayashi
Kyushu University, Japan
Egyptian Ministry of health- tropical and infectious diseases
walaah3@yahoo.com, furusyo@genmedpr.med.kyushu-u.ac.jp
The aim of the present study was to investigate the HP carrier rate HP-related endoscopic findings and
HP eradication response in patients with chronic HCV infection. in total, 76 patients with chronic HCV
infection (42 men and 34 women, age range 44 to 72 years) were enrolled into this study in comparison
with 228 HCV-negative subjects aged over 40 years living in same area HP infection rate was
significantly higher in 76 patients with chronic HCV infection (67 of 76, 88.2%) than in 228 HCVnegative subjects (158 of 228, 69.3%), The rates of gastric ulcer and gastritis were significantly higher
in the 67 HCV-infected patients with HP infection (32.8% and 76.1%) than in the 158 HCV-negative
subjects with HP infection (18.9% and 58.2%) and in the 70 HCV-negative subjects without HP
infection (7.1% and 35.6%). And after the eradication treatment of HP the successful eradication rate
was 95.3% (41 of 43) in the HCV-infected patients and 74.3% (90 of 121) in the subjects. These results
suggest that HP-related gastric diseases are serious problem for patients with chronic HCV infection
and markedly high eradication response is observed among them
EJISST2008 June 8~10
101
EJISST-ID 308
The role of CFTR protein in intestinal epithelial cell function and cystic
fibrosis
Aziz Awaad Aziz Mohamed and Kazunori Ishimura
The Tokushima of University
Sohag University
Aziz1_awaad@yahoo.com
Mutations in the gene coding for Cystic Fibrosis Transmembrane Conductance Regulator
(CFTR) prevents the Cl - Secretion needed to maintain the height of the fluid layer in intestinal
epithelial cell. In the epithelial cells of the intestine the balance between ion secretion and reabsorption
is a critical determinant of the height of the fluid layer that lines the intestine. The importance of ion
movement in this process is highlighted in cystic fibrosis, in the past studies CFTR interacts with a
multi-protein complex, which includes annexin 2 and S100A10, in a cAMP/PKA/ protein phosphatase
2B (PP2B) dependent manner. The complex can be disrupted by specific inhibitors of either PKA or
protein phosphatase 2B or exposure to peptides targeted to the complex. Initial functional studies have
demonstrated that pre-exposure to a PP2B inhibitor, which disrupts the complex, also reduces the
magnitude of CFTR currents in the cells, suggesting that complex formation is important for channel
function. Formation of the complex appears to be absent in cystic fibrosis cells, suggesting that the
association of the complex with CFTR and the multi-protein complex may be vital for normal cell
function. The aim of this study is to investigate the interaction between CFTR protein and the multiprotein complex using both molecular and functional approaches. Intestinal epithelial specimens from
both normal and cystic fibrosis transgenic rats, will be used as the model system. Techniques will
include: western blotting, immunofluorescence microscopy, transmission electron microscopy and the
information gained from this study will add to our understanding of intestinal epithelial cells functions
and the role of ion channels play in cystic fibrosis.
EJISST-ID 309
Expression of cytokine genes in head kidney and spleen cells of
Japanese flounder infected with N. seriolae
Mahmoud Tanekhy Amer and Masahiro Sakai
Miyazaki University
Alexandria University
tanekhyvet2020@yahoo.com
The expression of cytokine genes like interleukin-1 beta , tumor necrosis factor alpha and CCchemokine ( IL-1β, TNFα , CCC) was examined in HK and spleen of Japanese flounder infected with
N. seriolae . After infection, the mRNA form these organs extracted and cDNA constructed. The
expression of cytokine genes examined by the application of PCR technique using specific primers for
each gene. The results showed higher expression levels of TNFα in spleen, HK 1, 3 days post infection
while IL-1β was higher in spleen 24 hours and 3 days post infection, but in HK it was higher 2 hours
post infection at 10mg concentration. For CC-chemokines, IL-1β found to be highest 24 hours at 1 mg
concentration in spleen while in HK 2 hours at 10 mg concentration post infection. The results and
conditions were fully analyzed and discussed.
EJISST2008 June 8~10
102
SESSION 10: Health - Clinic and Practice (1-2)
EJISST-ID 006
Photoprotective effects of chemical peeling agents against ultravioletinduced photoaging in hairless mice
Mohamed Abdel-Daim, Yoko Funasaka, Hiroshi Matsunaka*, Masahiko Ooe* and Chikako
Nishigori
Kobe University, Japan
*Product Development, Tokiwa Pharmaceutical Co., Ltd., Japan
Suez Canal University, Egypt
mdaim2010@yahoo.com
Chemical peeling is one of the dermatological treatments available for certain cutaneous diseases and
conditions or improvement of cosmetic appearance of photoaged skin. Here, we assessed the
photochemopreventive effect of several clinically used chemical peeling agents on the ultraviolet (UV)irradiated skin of hairless mice. The peeling agents, 35% glycolic acid (GA) dissolved in distilled
water, 30% salicylic acid (SA) in ethanol, 10% and 35% trichloroacetic acid (TCA) in distilled water,
were applied to the back of UV-irradiated hairless mice every 2 (GA, SA, and 10% TCA) or 4 (35%
TCA) weeks for totally 18 weeks after establishment of 2 models of photoaged mice by UVB or UVA
irradiation for 14 weeks. Tumor number and incidence were evaluated and wrinkle formation was
assessed by replica taking. Skin specimens were taken from treated and non-treated area for evaluation
of hydroxyproline amount. All peeling agents used have shown to decrease the total number of tumors
as well as tumor incidence. Wrinkle formation was reduced in treated area compared with non-treated
area and hydroxyproline amout was also increased in the treated area. Our findings have clearly shown
that chemical peeling with GA, SA, and TCA help not only reduce wrinkles by increasing collagen
amount but also prevent UV-induced tumor formation in hairless mice. These results indicate that
chemical peeling with GA, SA, and TCA could serve as anti-photoaging treatment both in wrinkle
reduction and tumor prevention.
EJISST-ID 114
Predictors of short and long-term survival after adult living donor liver
transplantation
Walid Mohamed El Moghazy, Shinji Uemoto and Akio Koizumi
Kyoto University
Sohag University
moghazyw@gmail.com
The aim of study is to determine the pre-operative and operative risk factors for short and long-term
survival after adult living-donor liver transplantation (ALDLT). We analyzed a series of 408 patients
received primary ALDLT for end-stage liver disease at Kyoto University Hospital between 1998 and
2006.The outcome was defined as 90-day, 1-year and 5-year survival of the patients or survival of the
grafts. 44 pre-operative and operative variables were included for statistical analyses using Cox s
proportional hazard regression model. In statistical analysis, to prevent masking of the actual risk
factors affecting long term survival, we excluded 90-day survival during 1-year survival analysis and
excluded 90-day and 1-year survival during 5-year analysis using Cox s proportional hazard regression
model with Landmark method.Graft or patient survivals were 86%, 79% and 74% at 90-day, 1-year and
5-year respectively, more than 50% of graft or patient loss happened during the first 3 months post
LDLT. For 90-day survival multivariate Cox regression analysis showed that 2 HLA-DR mismatches,
operative blood loss, Model for End Stage Liver Disease (MELD score)>25, history of prior upper
EJISST2008 June 8~10
103
abdominal surgery excluding laparoscopy , creatinine clearance and diabetes were the risk factors.
For 1-year survival, MELD score>25 and ABO-incompatibility were independent risk factors. For 5year survival, hepatocellular carcinoma and ABO-incompatibility were independent risk factors.
For short-term survival, general condition of the patient and operative blood loss are determinants,
while pathogenesis of the liver disease is determinant for long-term outcome after ALDLT. In contrast,
immunological incompatibilities are constantly risk factors for ALDLT.
EJISST-ID 152
Immunohistochemical expression of ATX and AGK in Prostate Cancer
with relevance to Clinicopathological parameters
Mohammed Ahmed Abdel Muneem Nouh and Yoshiyuki Kakehi
Kagawa University
Sohag University
man5812001@yahoo.com
Lysophosphatidic acid is a bioactive phospholipid that may have a role in prostate cancer development
and progression. This study assesses the immunohistochemical expression of autotaxin and
acylglycerol kinase, the enzymes that produce LPA as a lipid intermediate; in PC specimens to evaluate
this role. Paraffin slides were prepared from tissue specimens of 96 patients who underwent radical
prostatectomy in our department between Jan. 2001 and Dec. 2005 and investigated the
immunohistochemical expression of ATX and AGK in PC tissues. We found that both enzymes are
significantly expressed (particularly AGK) in PC tissues. Both enzymes showed a significantly positive
(but low) expression in high-grade PIN lesions and a significant correlation with the Gleason pattern of
cancer foci examined (but not to the total Gleason score). Interestingly, heterogeneous expression
pattern significantly consistent with the Gleason grade of cancer foci was noticed in both. ATX was
positively expressed in the nuclear membranes of PC cells while AGK was solely limited to the
cytoplasm which may suggest a possible subcellular site of action for both enzymes. AGK-expression
was significantly correlated with the clinical stage and the prevalence of PSA failure outcome in PC
cases which may reflect the role of LPA in PC progression and invasiveness. These findings support
the oncogenic role of LPA in PC and provide a possible pathway that could be targeted in PC
treatment.
EJISST-ID 153
Human scavenger receptor class B type I is regulated by activators of
Peroxisome proliferators-activated receptor- in hepatocytes
Rania Abdel Muneem Ahmed and Toshihiko Ishida
Kagawa University, Japan
Sohag Education & Training hospital, Education & Training hospitals organization, Egypt
rora5812001@yahoo.com
High-density lipoprotein particles (HDL) play a critical role in cholesterol metabolism. Hepatic
scavenger receptor class B type I (SR-BI) binds HDL particles in mediating reverse cholesterol
transport of HDL and thus lowers the risk of atherosclerosis. Thiazolidinediones (TZDs), which are
known to have potent enhancing effects on insulin sensitivity, have been developed for the treatment of
non-insulin-dependent diabetes mellitus. TZDs are a high-affinity ligand for the peroxisome
proliferator-activated receptor (PPAR)-, which belongs to a nuclear receptor superfamily. In this
study, we examined the effects of TZD-PPAR- on hepatic SR-BI gene expression in Hep G2 cells.
Results showed that hepatic SR-BI mRNA and protein were increased by exposure toTZDs.
Transcriptional activity of human SR-BI promoter paralleled endogenous expression of the gene and
this activity was dependent on the dose of TZDs. We have investigated the influence on the promoter
activity of vector expressing PPAR and RXR co-transfected into HepG2 cells along with SR-BI
promoter/luciferase reporter gene constructs. PPAR or/and RXR was sufficient to induce the SR-BI
EJISST2008 June 8~10
104
promoter activity in HepG2 cells. Chromatin immunoprecipitation (ChIP) assay confirmed the binding
of PPAR- to the functional Peroxisome proliferators responsive element (PPRE) at -890 (5GTAAGACTGGTACACGAGGT- 3) -920 of SR-BI promoter lesion. The mutagenesis of the PPRE in
the SR-BI promoter abolished the ability of TZDs or PPARs to stimulate the promoter activity.
Together, these results indicate that the TZDs stimulation of SR-B1 expression in liver is mediated in
part by activation of the PPAR and RXR, and raise the possibility that the stimulation of hepatic SRBI expression using TZDs conditions provides a protective mechanism for accelerated atherosclerosis
in diabetes mellitus.
EJISST-ID 189
The Sex Differences of Cerebrospinal Fluid levels of Interleukin-8 and
Antioxidants in Asphyxiated Newborns
Mohamed Hamed Hussein, Ghada A. Daoud, Hisanori Sobajima and Hajime Togari
Nagoya University, Japan
Cairo University, Egypt
hamed@med.nagoya-cu.ac.jp and drmhamed@yahoo.com
The aim of this study was to find an explanation to why Newborn males are more sensitive to brain
injury than newborn females are. Methods: We used the neuron-specific enolase (NSE) levels in the
cerebrospinal fluid (CSF) for the classification of 32 newborns (19 males and 13 females) on their 5 thpostnatal-day. NSE levels were higher than normal (8.4±1.6 ng/ml) in 10 newborn males and 6 females
and were respectively considered asphyxiated male and female groups. Remaining newborns, 9 males
and 7 females, had normal CSF levels of NSE and were considered normal newborn male and female
groups. CSF samples were measured for 12 cytokines, using a cytokine array kit, and for total
hydroperoxide (TH) and biological antioxidant potentials (BAPs), using the free radical analytic
system. Results: Only CSF levels of IL-8, among the 12 cytokines measured, were higher in the
asphyxiated newborn females than in the other three groups. Mean CSF levels of BAPs in the
asphyxiated newborn females were higher compared to the other three groups, but significance was
detected only in comparison to the normal newborn males. Conclusions: This sex-related differences
in CSF levels of IL-8 and antioxidants in asphyxiated newborns, might explain the above sexual
dimorphism.
EJISST-ID 168
Novel role of HMG-CoA reductase inhibitor in keratinocyte proliferation
and migration
Mostafa Ibrahim Attia, I. Katayama and H. Murota
Osaka University
Cairo University
mosattia76@yahoo.com
LDL receptors (LDLR) are equally distributed on the cell surface and inside the cell of the basal layer,
while in the suprabasal layer, they are almost all intracellular. In the upper layers hardly any LDLR
molecules were seen. Thus it reflects the proliferative potential and differentiation status of
keratinocytes and it was expected in psoriasis, that LDLR were highly expressed in upper layers of
psoriatic epidermis. LDLR expression is regulated at different levels, and is affected by several factors.
we have investigated LDLR expression in healthy skin, atopic dermatitis and psoriasis and the effect of
statins on LDLR expression and on keratinocyte migration. We have found that LDLR are highly
expressed in psoriasis, moderately expressed in normal controls and poorly expressed in atopic
dermatitis. Topical application of HMG-CoA reductase inhibitors (statins), which are known LDLR up
regulators, to a mouse back skin has revealed an increase in the number of Ki-67 positive keratinocytes.
In vitro assays have shown that statins, in a certain concentration, have up regulated LDLR expression
EJISST2008 June 8~10
105
and they have increased keratinocyte migration in a dose dependent manner. These results indicated
that statins may influence keratinocyte behaviour via up regulation of LDLR.
EJISST-ID 198
Molecular biological studies on cancer gene therapy: regulation of
apoptosis and metabolosim
Salah M. elSayed and K.Fukui
Tokushima University
Sohag University
salahfazara@yahoo.com
Cancer occurs by the production of multiple mutations in a single cell that causes it to proliferate out of
control. Cancer cells are often different from their normal neighbors. Cancer cells have specific
phenotypic changes, such as rapid division rate, invasion of new cellular territories, high metabolic
rate, and altered shape. Several methods such as surgery, radiation, and chemotherapy have been used
to treat cancers. Gene therapy is the insertion of therapeutic genes into an individual's cells and tissues
to treat a disease, or silencing unwanted genes. Despite the promise of such approaches, a number of
difficulties remain to be overcome, the most important of which is the need for more efficient systems
of gene delivery. Gene delivery can be done by viral vectors, e.g adenovirus or non-viral vectors, e.g
plasmids and liposomes. Cancer gene therapy has several potential strategies, e.g enhancing the
immunogenicity of the tumor, enhancing immune cells to increase anti-tumor activity, inserting a
sensitivity or suicide gene into the tumor. Pediatric malignancies, e.g brain tumours, leukemia and
lymphoma are good targets for gene therapy. In this study, we use gene-directed enzyme prodrug
therapy strategy by using therapeutic genes, e.g nucling which has apoptosis-inducing activity and Damino acid oxidase which has apoptosis-inducing activity by production of hydrogen peroxide.
Transfering human D-amino acid oxidase gene to tumour tissue is expected to produce the cytotoxic
hydrogen peroxide which mediates oxidative stress and cytotoxicity to cancer cells on adminstration of
the non-toxic substrate, D-alanine.
EJISST-ID 222
Pediatrics cardiology
Manal M. Helmy Nabo and Shoji Kagami
Tokushima University
Sohag University Hospital
abod000000@yahoo.com
Cardiological diagnostic and therapeutic techniques e.g echocardiography and catheterization improved
pediatric practice and allowed better management of pediatric diseases. Cardiac catheterization is both
diagnostic and therapeutic. Echocardiography is a sure diagnostic technique in congenital heart disease,
rheumatic heart disease. Echo is used to evaluate cardiac lesions and is a prerequisite before cardiac
surgery. It is routinely done in some genetic diseases e.g Duchenne muscle dystrophy in which
cardiomyopathy may occur and trisomy 21. Duchenne muscular dystrophy is caused by a mutation of
the dystrophin gene whose protein product is responsible for the connection of muscle fibers to the
extracellular matrix through a protein complex containing many subunits. Muscle wasting begins in the
legs and pelvis, then progresses to the muscles of the shoulders and neck, followed by loss of arm
muscles and respiratory muscles. Calf muscle enlargement (pseudohypertrophy) is quite obvious.
Cardiomyopathy may occur, but the development of heart failure is rare. Genetic counseling is advised
for people with a family history of Duchenne muscular dystrophy. Duchenne muscular dystrophy can
be detected with about 95% accuracy by genetic studies performed during pregnancy. The aim of the
current study is to perform a cardiological evaluation of selected cases of congenital heart disease and
duchenne muscular dystrophy using echocardiography and cardiac catheterization and aiming at
improving therapeutic modality for these diseases.
EJISST2008 June 8~10
106
EJISST-ID 154
Evaluation of Coronary Calcium Score by Multidetector Computed
Tomography in Relation to Endothelial Function and Inflammatory
Markers in Asymptomatic Individuals
Mahmoud Ramadan Mohammed and Yoshifusa Aizawa
Niigata University
Mansoura University
amamod2020@yahoo.com
Background Coronary calcification has been correlated with the presence and extent of coronary artery
disease (CAD), so in the present study the associations between coronary artery calcification score
(CACS) and endothelial dysfunction, as well as the important inflammatory markers C-reactive protein
(CRP), interleukin (IL)-6, and oxidized low-density lipoprotein (OxLDL), were studied in
asymptomatic individuals at intermediate risk for CAD. Methods and Results The study group
comprised 177 subjects (103 males) aged 50.6 years on average. CACS was measured by multidetector
computed tomography using the Agatston method. Endothelium-dependent flow-mediated dilatation
(FMD) and endothelium-independent nitroglycerin-mediated dilatation (NMD) were measured by
high-resolution external brachial ultrasound. Coronary artery calcification (CAC) was detected in 82
subjects (52 males), and the median CACS was 143 [31-311.25] units. After adjusting for gender and
body mass index, log (CACS+1) correlated positively with age (r=0.401, p<0.001) and IL-6 levels
(r=0.442, p<0.001), and negatively with FMD (r=0.511, p<0.001). The correlations of log (CACS+1)
with CRP and OxLDL levels, and with NMD, were non-significant. In a multivariate-adjusted logistic
regression model, age (odds ratio (OR) =1.083 [1.014-1.156]), serum IL-6 level (OR=3.837 [2.166 6.798]) and FMD (OR=0.851 [0.793-0.913]) were significantly and independently associated with
CAC. Conclusions Peripheral endothelial function inversely correlated with CACS, whereas IL-6 level
was associated with CACS. Testing for endothelial function and IL-6 level may improve cardiovascular
risk assessment and help target the therapeutic strategies in asymptomatic patients at intermediate CAD
risk.
EJISST-ID 310
Utilization of Polymethyle-methacrylate (PMMA) interposition as an
alternative to the different modalities of cervical interbody fusion for
treatment of single level cervical disc disease
Tamer I. Orief and Masakazu Takayasu
Aichi Medical University School of Medicine
General Health Insurance Organization (Gamal Abd Naser Hospital)
tamerorief@yahoo.com
Reconstruction of disc space after anterior cervical discectomy is accepted to prevent segmental
collapse, preservation of cervical alignment and keeping the neural foramina uncompromised. But
economic alternative method (PMMA) is needed to replace the inconvenient iliac crest bone graft and
the expensive cervical cage. The aim of the present study is to evaluate the Polymethyle-methacrylate
(PMMA) interposition as an alternative to the different methods of disc space reconstruction (cervical
cage and iliac crest bone graft) after anterior cervical discectomy. This study was conducted on 60
patients where the patients were divided into three groups according to the method of disc space
reconstructon. Post operative short and intermediate term clinical (VAS scale) , radiological and
functional (odom’s criteria) outcomes were evaluated. The results using of PMMA implant yields a
satisfactory short and intermediate term clinical and functional (94.4%)outcomes, although it is
hindered by not providing satisfactory bone fusion (20%) when compared to ABG group (72.2%) and
CC group (66.6%) after six months postoperatively .It can be concluded that PMMA implant
interposition is an established method with equivalent clinical results to the conventional grafting
procedures (ABG and CC) providing: No donor site harvesting complications, easiness of its
EJISST2008 June 8~10
107
preparation and surgical procedure as evidenced by no addition to operative time and the shortening of
hospital stay and inexpensive grafting material.
EJISST-ID 101
Various reconstructive modalities for diabetic foot ulcer
Ahmed Kamal Osman and Nakanishi H.
Tokushima University
Assiut University
ahmedk.osman@yahoo.com
Diabetic foot problems are common throughout the world, resulting in major medical, social and
economic consequences for the patients and their families. Diabetic foot ulcer is the commonest major
complication among diabetic patients and has been recognized as an important antecedent of lower
extremity amputation. Diabetic foot ulcer occurs as a result of many factors such factors include
peripheral neuropathy, atherosclerotic peripheral arterial disease and mechanical changes in
configuration of the bony architecture of the foot. Peripheral neuropathy causes loss of protective
sensation and loss of coordination of muscle groups in the foot and leg, both of which increase
mechanical stresses during ambulation. Foot deformities, which are common in diabetic patients, lead
to focal areas of high pressure. When an abnormal focus of pressure is coupled with lack of sensation, a
foot ulcer can develop. Most diabetic foot ulcers form over areas of bony prominences especially when
calluses or hammer-toe formation lead to abnormally prominent bony points. Rigid deformities have
also been associated with the development of diabetic foot ulcers. Peripheral neuropathy and
atherosclerotic peripheral arterial disease, all of which occur with higher frequency and intensity in the
diabetic patients. as the vast majority of amputation are preceded by foot ulcers, understanding of
causative pathways to ulceration is essential to can reduce the incidence of ulceration and subsequences
amputation and if ulceration occur we should manage it as early as possible to decrease incidence of
amputation so in our study we use various reconstructive modalities for treatment of diabetic foot ulcer
to decrease incidence of amputation
EJISST-ID 117
Two different techniques for donor hepatic transection: CUSA with
Bipolar cautery versus CUSA with TissueLink™. A randomized
controlled trial
Mohammed Saied Abo Hedaya and Shinji Uemoto
Kyoto University, Japan
Theodore Bilharz Research institute, Egypt
hedayamsm@yahoo.com.
The aim of this study was to compare Cavitron Ultrasonic Surgical Aspirator (CUSA) with bipolar
cautery (BP) to CUSA with TissueLink (TL) in terms of efficacy and safety for hepatic transection in
living donor liver transplantation. Twenty-four living liver donors (n =12 each group) were randomized
to undergo hepatic transection using CUSA with BP or CUSA with TL. Blood loss during parenchymal
transection and speed of transection were primary end-points, whereas degree of postoperative liver
injury and morbidity were secondary end-points. Median blood loss during liver transection was
significantly lower in the TL group than in the BP group (195.2 ± 84.5 vs. 343.3 ± 198.4 ml; P =
0.023), and liver transection was significantly faster in the TL group than in the BP group (0.7 ± 0.2 vs.
0.5 ± 0.2 cm²/min; P = 0.048). Significantly fewer ties were required during liver transection in the TL
group than in the BP group (15.8 ± 4.8 vs. 22.8 ± 7.9 ties; P = 0.023). The morbidity rate was similar
for both groups. CUSA with TL is superior to CUSA with BP for donor hepatectomy in terms of blood
loss and speed of transection with no increase in morbidity.
EJISST2008 June 8~10
108
SESSION 11: Health Diagnosis and Health Management (1)
EJISST-ID 137
Research on genetics of respiratory diseases in Japanese and Egyptian
populations, Lung mucus , regeneration with HGF and stem cells
Ahmed Hegab and Mutsuo Yamaya
Tohoku University
hegabb@hotmail.com
Since I came to Japan in 2000, I worked on several projects aiming at improving our understanding of
diseases and trying to develop new treatments. Due to limited space, I will describe only the most
important projects. In the first project, I searched for polymorphisms and haplotypes that predispose
smokers to develop Chronic Obstructive Pulmonary Disease (COPD) in Japanese and Egyptians. Ten
genes have been studied. Several polymorphisms and haplotypes were identified as risk factors for
COPD in Japanese and Egyptians. In the second project, I studied the relation between CLCA1 and
EGFR genes and their interaction with MUC5AC pathway for mucus secretion in rat lungs when
exposed to cigarette smoke. A new complex signaling pathway was described and a novel treatment for
excessive mucus secretion in various lung diseases was suggested. In the third project, I could heal lung
damage in mouse-model of emphysema by using intra-nasal instillation of Hepatocyte Growth Factor
(HGF). I could prove that the mechanism of healing includes stem cell recruitment and epithelial
multiplication. Finally, I tried to isolate and characterize stem cells from the lungs of both mouse and
human. I could isolate and grow several mouse and human progenitor cells that are self-renewing and
expressing several markers that are commonly detected on stem cells. I could induce the mouse lung
stem cells to differentiate into alveolar and epithelial cells which mean that these cells are multipotent.
This is the first study that describes the presence of multipotent stem cells in the lung.
EJISST-ID 064
Mechanisms of Enhancement of TRAIL Tumoricidal Activity Against
Human Cancer Cells of Different Origin by Dipyridamole
Ahmed Elsayed Goda and Toshiyuki Sakai
Kyoto Prefectural University of Medicine
Tanta University
ahmed29102005@yahoo.com
Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) has emerged as an attractive
cytokine that selectively targets cancer cells, however its efficacy has been challenged by a number of
resistance mechanisms. Therefore, the current study investigated the potential of dipyridamole to
enhance TRAIL efficacy and the probable underlying mechanisms. Dipyridamole dramatically
sensitized p53-mutant human cancer cell lines: SW480, MG63 and DU145, to the antitumor activity of
TRAIL, as evidenced by enabling TRAIL to efficiently cleave initiator and executioner caspases.
Although dipyridamole upregulated both Death Receptor 4 (DR4) and DR5 and increased their cell
surface expression, RNA interference revealed a preferential dependence on DR5. Moreover,
dipyridamole inhibited survivin expression and its important consequences were confirmed by small
interfering RNA. Mechanistically, dipyridamole induced transcriptional shutdown of survivin
expression accompanying G1 arrest that was characterized by downregulation of D-type cyclins and
cyclin-dependent kinase 6 (cdk6). In addition, a transcriptional mechanism powered by
CCAAT/enhancer-binding protein (C/EBP) homologous protein (CHOP) induction was responsible for
DR5 upregulation by dipyridamole. Importantly, dipyridamole-induced enhancement of TRAIL
efficacy and alterations of protein expression were independent of either protein kinase A or protein
kinase G. In conclusion, findings of the present study described novel mechanisms of dipyridamole
action and highlighted its promising use as a potential enhancer of TRAIL efficacy.
EJISST2008 June 8~10
109
EJISST-ID 150
Bacteriocin production in the compost process
Hosnia Abdel-Mohsein and Nakai Yutaka
Tohoku University
Assiut university
hosnia1@yhoo.com
The application of raw manure or composted one in agricultural practice has potentially risks of
contamination of foodstuffs with pathogenic microbes. As one of effective methods to control of
pathogenic bacteria, bacteriocins were developed for food preservation. Bacteriocins are the candidate
to control pathogens in waste treatment processes. Then we observe bacteriocin-producing microbes in
compost processes, and investigate the effects of these bacteriocins to pathogenic microbes.
Experiments were conducted on the cattle manure composting system in Kawatabi Field Science
Center, Tohoku University. The facility has a capacity for the treatment of manure from 200 cattle. The
compost pile was composed from cow manure and saw dust. The pile was subjected to two treatments.
The first and second treatments lasted for 4 and 8 weeks, respectively. Ten compost samples were
collected at different stages of the process. In these samples bacteriocin-producing microbes were
examined using the following indicator pathogenic microbes: E.coli O157:H7 ATCC 43888,
Salmonella typhimurium EF 85-9, Staphylococcus aureus ATCC 6538P, Enterococcus faecalis ATCC
19433, Yersinia enterocolitica ATCC 9610, Campylobacter jejuni ATCC 29428. Some of isolated
microbes showed inhibitory activity against some of these indicator pathogens. This is the first report
indicating the presence of bacteriocin-producing microbes in the compost processes. Isolated microbes
can be used for controlling pathogens in the compost processes without environmental pollution such
as chemicals.
EJISST-ID 096
Percutaneous Treatment of HCC
Hamdy Saad Mohammed, Ali Taha Ali Hassan, Adel A. El-Sayed and Tsutomu Masaki
Kagawa University
Sohag University
Hamdy119@yahoo.com
Hepatocellular carcinoma (HCC) is worldwide health problem. Between all available treatment
options, percutaneous ethanol injection therapy (PEIT) and radiofrequency ablation (RFA) played a
pivotal role. Moreover, recently their combination was proven to be more effective and offers better
tumor control than either option alone. Unfortunately, some tumors are very difficult to be treated due
to poor visualization by ultrasonography (US). To overcome this difficulty, percutaneous ethanollipiodol injection therapy (PELIT) either alone or combined with RFA (PELI-RFA) was first reported
in our department as a new promising treatment option. In this study, PELIT and PELI-RFA was done
for large number of cases. Patients: Between July 2006 and December 2007, we treated 72 tumors in 46
patients (35 male and 11 female), mean age 72.89±6.60, and mean tumor size was 19.92±8.32 mm
(range from 7.5 -42 mm). According to tumor location, we used PELIT in 54 tumors and PELI-RFA in
18 tumors. Treatment was repeated at one week intervals till complete tumor necrosis was achieved.
Results: Complete tumor necrosis was achieved after 1 session in 26 tumors, after 2 sessions in 24
tumors, after 3 sessions in 10 tumors, 4 sessions in 5 tumors and 5 sessions in 7 tumors. The mean
amount of PELIT injection was 10.9 ml (range 1-26 ml). Conclusion: For poorly visualized tumors by
US guidance, both PELIT and PELI-RFA are effective in achieving complete tumor necrosis.
EJISST2008 June 8~10
110
EJISST-ID 054
NERVE TRANSFER TO DELTOID MUSCLE USING THE MOTOR
BRANCHES OF THE TRICEPS MUSCLE AFTER UPPER BRACHIAL
PLEXUS AVULSION INJURIES
Waleed Riad Saleh and Hiroshi Yajima
Nara Medical University
Assiut University
wareethrs@yahoo.com
PURPOSE: To report our experience of restoration of shoulder abduction after upper brachial plexus
avulsion injuries by transferring triceps motor branches to axillary nerve. METHODS: Four patients
had the nerve transfer to axillary nerve trunk, using triceps long head branch in two and lateral head
branch in two. Mean age of the patients was 34.7 years and interval between injury and surgery ranged
from 3 to 8 months (average 5 months) Patients were evaluated by measurement of shoulder abduction
range and motor recovery of the deltoid muscle. RESULTS: All patients recovered shoulder abduction.
Shoulder abduction ranged from 40 to 180 degrees (average 123 degrees) and deltoid muscle recovery
ranged from grade M2 to M5 (average M3). No clinical donor nerve deficits were observed.
DISCUSSION: this method of nerve transfer is reliable for deltoid reconstruction after upper brachial
plexus avulsion injuries. Postoperative re-education and voluntary control were easy and fast because
of synergistic motions of the target muscle (i.e. elbow extension is synergistic to shoulder abduction). It
is strongly recommended to be combined with neurotization of the suprascapular nerve by spinal
accessory nerve for better improvement of both shoulder abduction and external rotation
EJISST-ID 145
Analyses of Fluourotelomer alcohols (FTOHs) in surface waters using
Gas chromatography- Mass spectrometry (GC-MS)
Manal AM Mahmoud
Kyoto University
Assiut University
molyvip@yahoo.com
Fluorotelomer alcohols (FTOHs) are recognized now as new environmental pollutants because of their
ubiquitous occurrence in air environment in many industrial countries. FTOHs a major raw material
used in various fluoropolymers and fluorosurfactants. The ecological fates of these telomer alcohols
remain largely unknown. The aim of this study is to investigate the fates of FTOHs in surface waters.
To achieve this aim a simple and convenient method was developed for the determination of FTOHs
(6:2 FTOH, 8:2 FTOH, 10:2 FTOH, PFDO, PFUdO, 8:2 FTOAcr, FTOMethacryl, 8:2 FTOlefin and
NEtFOSA) using GC/MS. Surface water (26), wastewater treatment plants (25) and rainwater (9)
samples were collected from Keihan area in 2007 and 2008 and filtrated using glass filter. Dissolved
FTOHs were extracted from water by shaking with either activated carbon filter (ACF) felts or t-butyl
methyl ether (MTBE). The analysis showed that MTBE method was more reliable in detecting lower
concentration of the target analysts than ACF method. Analyses demonstrated that FTOHs were
discharged into surface water from water discharge sites, although their levels are small. 8:2 FTOH,
10:2 FTOH and 8:2 FTOAcr were ubiquity found from surface water samples: their concentrations
ranged from non detected levels to 25.4, 8.8 and 0.16 ng/L, respectively. The present study provided
evidence that water disposal sites are one of the sources of FTOHS. Further study is warranted to
elucidate the origin of those telomer alcohols.
EJISST2008 June 8~10
111
SESSION 12: Health Diagnosis and Health Management (2)
EJISST-ID 149
Endoscopic Ultrasound Fine Needle Aspiration (EUS-FNA) and
Endoscopic Retrograde Cholangiopanreatography (ERCP) Brush
Cytology in Diagnosis of Biliary and Pancreatic Duct Strictures
Wael A. Abbas, Mohamed Ali Tohamy and Kenji Yamao
Aichi Cancer Center Hospital
Assiut University
Drwaelabbas@yahoo.com.
Pathological diagnosis of pancreatico–biliary strictures (PBSs) is still a challenge. The objective of this
study is to compare the diagnostic accuracy of ERCP brush cytology and EUS-FNA in cytological
diagnosis of PBSs. Methods: A retro-prospective study was designed, 110 patients with pancreatic
and/or biliary stricture underwent ERCP brush cytology and EUS-FNA from January 2001 to January
2008. ERCP brush was cut and bile or pancreatic juice was added to the same tube to increase cellular
material from March 2006. FNA sample adequacy was provided using air-dried Diff Quik stained
smears. Alcohol fixed Papanicoloau stained smears and cell block histopathology were evaluated
before providing a final report. Final diagnosis was confirmed by surgery in 22 patient, clinical follow
up for more than 1 year in 88 patients. Results: 34 patients (30.4%) with benign strictures (Chronic
Pancreatitis (12.7%), Autoimmune pancreatitis (8.1%), Mass forming pancreatitis (8.1%)). And 76
patients (69%) have malignant strictures (Pancreatic carcinoma (59%), Cholangiocarcinoma (9%), Gall
Bladder carcinoma with metastasis (2.7%)). Brushing was done in CBD (29%) and in MPD (70.9%).
Insufficient material was obtained in brushing of 6 cases and FNA cytology of 1 case, and they
excluded from statistical analysis. EUS-FNA and ERCP brushing sensitivity for cytological diagnosis
of PBSs was (84.24%, 25%) with specificity (100%, 100%) positive predictive value (100%, 100%)
and negative predictive value (75%, 35%) respectively. Conclusions—EUS-FNA cytology has a higher
sensitivity for cytological diagnosis of PBSs than ERCP brushing cytology, and it is useful in the
assessment of suspected pancreatico–biliary neoplasia.
EJISST-ID 160
A New Era for the Dry Eye Diagnosis
Osama M.A. Ibrahim, Murat Dogru and Kazuo Tsubota
Keio University School of Medicine, Japan
Alexandria University, Egypt
osamaibrahim82@yahoo.com
Purpose: The estimation of tear meniscus volume is an important, but often overlooked aspect of the
dry eye (DE) examination. We performed a prospective controlled study to evaluate the effectiveness
of the new strip meniscometry (SM). Methods: SM was applied on 130 eyes of 65 patients (16 males,
49 females; mean age, 42 ± 7.2 years) with definite dry eye and on 43 control subjects (24 males, 19
females; mean age, 40 ± 8.5 years). Tear meniscus volume was quantified using SM of the central
lower lid tear meniscus for 5 seconds. Tear function tests including tear break up time (BUT),
fluorescein (F), Rose Bengal (RB) staining and Schirmer test (ST) were also performed. Results: The
SM scores were 3.19 ± 2.12 mm and 5.6 ± 1.7 mm, respectively (p< 0.001). The mean BUT values
were 4.14 ± 1.65 and 9.14± 2.46 sec in dry eye patients and controls respectively. Both the RB and F
scores were 0 in the control group, and were 2.16 ± 2.15 and 2.42 ± 2.34 points, respectively, in the dry
eye group (p < 0.001). The mean ST value in the DE patients was 5.28 ± 2.43 mm compared to 14.11 ±
9.46 in the controls. A significant correlation between the SM and Schirmer test was found (r: 0.5292,
EJISST2008 June 8~10
112
p < 0.001). Conclusions: Strip meniscometry is a swift, noninvasive and promising method for
assessing the tear meniscus volume, which has potential applications for the diagnosis, evaluation and
treatment of dry eye syndromes.
EJISST-ID 179
Predictive factors of worsening of esophageal varices after balloonoccluded retrograde transvenous obliteration in patients with gastric
varices
Kamal Elsamman and Tetsuo Arakawa
Osaka City University
Sohag University
el_samman@yahoo.co.uk
Background and objective. Although balloon-occluded retrograde transvenous obliteration (B-RTO) is
useful for management of gastric varices, worsening of esophageal varices is the most important
complication of B-RTO. The predictive factors of worsening of esophageal varices have not been
evaluated in detail. This study was designed to evaluate the role of endoscopic color Doppler
ultrasonography (ECDUS) in detection of possible risk factors for worsening of esophageal varices
after B-RTO. Methods. A total of 39 cirrhotic patients with high-risk gastric varices successfully
treated by B-RTO were included in this study. All patients underwent ECDUS before B-RTO to
measure hemodynamic parameters of gastric varices and regular endoscopic follow up after B-RTO to
detect worsening of esophageal varices. The risk factors were analyzed by Cox proportional hazards
regression. Results. Worsening of esophageal varices was found in 24 (61.5%) patients. The presence
of esophageal varices before B-RTO and lower degree of liver dysfunction (Child-Pugh class B) were
significant risk factors for worsening of EV after B-RTO (risk ratio [RR] 5.81, 95% confidence interval
[CI] 1.71-19.77 and RR 2.92, 95%CI 1.21-7 respectively). High resistance index (0.24<=), measured
by ECDUS, is also risk factor for worsening of esophageal varices after B-RTO (RR 4.06, 95%CI 1.1414.38) and increase in resistance index is associated with worsening of esophageal varices (p for trend
= 0.028). Conclusion. The presence of esophageal varices, higher Child-Pugh class, higher resistance
index assessed by ECDUS before B-RTO were significant risk factors for worsening of esophageal
varices after B-RTO.
EJISST-ID 216
Chemoprevention and theraputic treatment of basal cell carcinoma
(BCC)
Moshira M. Hassan and Arase S.
Tokushima University, Japan
Assiut Hospital, Ministry of Health, Egypt
moshmohahm@yahoo.com
Basal cell carcinoma (BCC) is the most common cutaneous malignancy in human and about 75 percent
of skin cancer. It can be destructive and disfiguring by growing and invading the surrounding tissue.
BCC is a malignant growth of basal cell layer that line the deepest layer of the epidermis and from
basal keratinocyte of hair follicles and sweat ducts and occurs more often in men more than in women.
the ultraviolet ray via the sun light is responsible for 90 percent of BCC through damaging DNA and
its repair system, and also causing mutations in tumor suppressing genes, so it occurs most frequently
on the sun exposed area of the body as face, ears, neck, scalp, shoulders and back and usually is seen
after the age of 40 years, but those seen in patients who are younger than 35 tend to be more
aggressive. The understanding of mutations that are known to activate Hedgehog (Hh) signaling
pathway genes, including patched (PTCH), Sonic Hedgehog (Shh) and smoothened (smo) has
substantially expanded. Our current understanding of the genetic basis of BCC development, ectopic
activation of the Hedgehog (Hh) signaling pathway has recently been shown to be involved in several
EJISST2008 June 8~10
113
malignancies such as basal cell carcinoma of the skin. There are different lines of treatment of BCC
such as curettage and electrodessication, surgical excision, radiotherapy, cryotherapy and Mohs
micrographic surgery and there are some incidence of recurrence in each method so our study aiming to
understand the genetic basis of BCC development and use some drugs as a therapeutic treatment of
BCC.
EJISST2008 June 8~10
114
SESSION 13: Information & Communications Technology(ICT)
and Supercomputing
EJISST-ID 271
Embedded Systems Design and Technology
Mona A. Abo El-Dahb and Yoichi Shiraishi
Gunma University
Helwan University
monadahb@yahoo.com
Nowadays embedded systems technology issue is a vital for human mankind because our lives become
more dependent on digital information that is embedded in our environment. The applications of
embedded system not only for safety critical applications such as automotive devices and controls,
railways, aircraft and medical devices but also covers all communications devices, modern home
application , business equipment and office automations as fax machine, copiers, printers and scanners.
This research presents design and programming of embedded system technology that is representing
through the case study for one of the automobile applications. A number of various aspects based on
embedded system such as processor technology, IC technology, hardware and software co-design are
investigated in this research. Evaluations for the cost, time and technology benefits will be gained from
the use of embedded system technology for the selected application are proposed. The embedded
design, serious problems are its design cost and its reliability. One of the reasons for these problems is
that the specific hardware can not be available when designing the embedded software, because the
hardware is also under development. Therefore, our research is focused on the automatic generation of
the hardware simulator from its specifications. The basic idea of our approach is to utilize the
combination of the object oriented software design and the model base design.
EJISST-ID 009
Material Classification using Spectral Reflectance Information
Abdelhameed Ibrahim and Shoji Tominaga
Chiba University, Japan
Mansoura University, Egypt
Ibrahim@graduate.chiba-u.jp
In our work, we focus on material classification of a printed circuit board based on surface-spectral
reflectance information. This spectral information is measured by using multi-spectral imaging system.
First, we describe the camera system for observing different circuit board materials and how we can
capture their spectral data. The imaging system consists of a LCT (Liquid-crystal tunable) filter, a
monochrome CCD camera, macro-lens, and a personal computer. This system enables capabilities in
spectral image processing that cannot be performed by the general RGB imaging system. The spectral
images are captured in the region of visible wavelength at two illumination directions to distinguish
among different board elements. In addition, the illumination noise is considered. Second, a proposed
algorithm based on the estimated spectral reflectance is used directly to classify circuit board materials
into five element regions (1) silk-screen prints, (2) metal wires, (3) resist metal, (4) footprint, and (5)
substrate. The proposed algorithm can be used for different parts of a real circuit board. Finally, the
performance of our imaging system and the proposed algorithm is examined.
EJISST2008 June 8~10
115
EJISST-ID 236
Meta-Heuristics Programming: Memetic Programming
Emad Hamdy Ahmed and Masao Fukushima
Kyoto University
Assiut University
hamdy@amp.i.kyoto-u.ac.jp
The core of artificial intelligence and machine learning is to get computers to solve problems
automatically. One of the great tools that attempt to achieve that goal is Genetic Programming (GP).
GP is a generalization procedure of the well-known meta-heuristic of Genetic Algorithm. In addition,
meta-heuristics have shown successful performance in solving many combinatorial search problems. In
this paper, we introduce a more general framework of meta-heuristics called Meta-Heuristics
Programming (MHP) as general machine learning tools. MHP framework tries to cover many of the
well-known meta-heuristics as special cases. In addition, MHP framework generalizes the data
structures used in the most of ordinary meta-heuristics to be tree data structures instead of bit strings or
vectors of numbers. As alternatives to GP, Memetic Programming (MP) is proposed as a special
procedure of MHP frameworks. One of the main features of MHP is to exploit local search in order to
overcome some recently addressed drawbacks of GP, especially its highly disruption of its main
operations; crossover and mutation. Finally, we discus the performance of the MP method through two
types of benchmark problems; symbolic regression problem and 6-Bit multiplexer problem. We apply
MP method to study the efficiency of the local search over tree space. Then, we introduce some
comparisons between MP method and the GP method.
EJISST-ID 255
Design and Evaluation of Data-Parallel Algorithms on a Matrix Processor
Ahmed Sherif Zekri and Stanislav G. Sedukhin
The University of Aizu, Japan
Alexandria University, Egypt
ahmedzekri@yahoo.com
The idea of attaching accelerators to general-purpose processors for enhancing the compute-intensive
parts of applications has been adopted and is now getting more attention due to approaching the
physical limits of VLSI technology. Our motivation in this research is that the matrix multiply-add
(MMA) is a pervasive operation, and many scientific, engineering, and signal processing applications
can be formulated in terms of this operation. Moreover, the trend in chip-manufacturing is to integrate
more processing units or cores together to handle the diverse demands of current and future
applications. However, many problems remain unsolved such as the interconnection topology that
guarantees scalability, the applications that could benefit from all of these parallel resources, the
memory organization that keeps pace with the powerful processing speeds, etc. We propose a model of
a many-core matrix processor consisting of a scalar unit augmented with NxN simple cores tightly
connected into a 2D torus SIMD matrix unit. The matrix unit is optimized for executing fine-grained
NxN MMA operations in the minimal computing time. We formulate the alignment operations
including the matrix transpose as MMA operations. Using a decoupled load/store unit, we could
overlap the alignment overhead with the load/store operations. To evaluate the merits of the proposed
matrix processor, two fundamental linear algebra algorithms are designed and analytically evaluated:
the Level-3 BLAS kernel, GEMM, and the LU factorization with partial pivoting. For the GEMM
kernel, the maximum speed of computing measured in FLOPs/cycle is approached for different matrix
sizes, n, and block sizes, N. The speed of the LU factorization for relatively large values of n ranges
from around 50-90% of the maximum speed depending on the model parameters. Overall, the
analytical results show the merits of using the matrix unit for accelerating matrix-based applications.
EJISST2008 June 8~10
116
EJISST-ID 088
Cross-Layer Design for Power Efficient Wireless Ad Hoc Networks
Ghada Khoriba and Jie Li
Tsukuba University, Japan
Helwan University, Egypt
khoriba@osdp.cs.tsukuba.ac.jp , lijie@cs.tsukuba.ac.jp
In wireless ad hoc networks, nodes are allowed to communicate directly to one another using wireless
transceivers without the need for a fixed or centralized infrastructure providing communication
facilities among end-users. Some scenarios where an ad hoc network could be used are business
associates sharing information during a meeting, military personal relaying tactical and other types of
information in a battlefield, and emergency disaster relief personal coordinating efforts after a natural
disaster such as a hurricane, earthquake or flooding. In such scenarios, maximizing the network
lifetime is a very important issue since recharging battery is hard to do. We provide a cross-layer
approach to maximize the network lifetime by integrating and optimizing routing, topology control,
and channel assignment protocols. The cooperation among layers to enable performance enhancement
is important and useful in wireless ad hoc networks. Cross-layer approaches can achieve a global
optimization as the independent decision on different layers for achieving a local objective would
deteriorate the performance of the other layers leading to a failure in achieving the main goal. The main
features of our approach is that it depends on choosing the minimum power level at each node and
minimum power routing path according to some quality of service constraints. We extend the existing
AODV protocol by adding the new cross-layer integration to implement our idea and test its effects on
the existing routing protocols.
EJISST-ID 119
Access Point Allocation in Indoor Environments for Wireless Mesh
Networks
T.H. Farag and and Nobuo FUNABIKI
Okayama University
Cairo University
hftamer@sec.cne.okayama-u.ac.jp
We have studied WIMNET (Wireless Internet access Mesh NETwork) as a flexible and inexpensive
large scale access network to the Internet. WIMNET is composed of multiple access points (APs) as
wireless routers, where each AP has multi-hop wireless connections with others by the wireless
distribution system (WDS). In WIMNET, communications between APs for Internet Access can
become the bottleneck due to their multi-hop link activations. Besides, link quality may be degraded by
obstacles such as walls in indoor environments. Thus, the proper allocation of APs is essential, such
that the maximum hop count between APs should be minimized and any host in the field must be
reached from at least one AP. In this work, we formulate this AP allocation problem in indoor
environments for WIMNET with the proof of the NP (non-deterministic polynomial time)
completeness. Then, we present its three-stage heuristic algorithm composed of the initial AP
allocation, the AP allocation optimization, and the association host optimization. The effectiveness of
our approach is verified through extensive simulations using our WIMNET simulator.
EJISST2008 June 8~10
117
EJISST-ID 132
Comparative Study between Three Types of Down-Conversion Mixers
Giving Emphasis on Sampling Mixer for Wireless Applications
M. A. ABDELGHANY, R. K. Pokharel, H. Kanaya and K. Yoshida
Kyushu University
Minia University
abdelghany@yossvr3.ed.kyushu-u.ac.jp
Rapid growth of 3G communication systems increases demands of high performance, small size, and
high speed microwave devices, and circuits to meet these demands. One of the main blocks of the
communication Front-End Receiver is the “MIXER”, which is used to translate a high input radio
frequency (RF) to a lower intermediate frequency (IF). There are many types of Mixer. The three main
configurations are “Gilbert Cell Mixer”, which is used successfully for many years in RF receivers,
second is Resistive Ring architecture which does not produce any positive conversion gain of the
mixer, and the new architecture is “Sampling Mixer”, which has drawn many attention in recent times
because it provides a good performance and no inductors are necessary to realize a sampling mixer,
instead it uses a sampling switch and a digital filter. As the mixer performance can affect over all
receiver operation, especially for linearity, harmonic distortion, and noise, so a comparative studies will
be carried out among three types of mixers topology first using CAD tools and in later part, the focus is
given on the designing of a high performance sampling using new digitally techniques to meet the
demands of wireless systems.
EJISST-ID 133
Voice over IP-Networks Performance Analysis and Enhancement
Ahmed M. Shawish and Susumu Horiguchi
Tohoku University
Ain Shams University
ahmedmg@hotmail.com
There are about 1 billion fixed telephone lines and 2 billion cell phones in the world that use the
traditional PSTN systems. Soon, they will move to IP-networks based on open protocols known as
Voice over Internet Protocols (VoIP). This migration has already begun and will never stop not only
due to the cost advantage and ubiquity but also due to enormous benefit of integrating voice and data
into a single infrastructure. The current wired and wireless IP-networks are originally designed to
handle the traditional data traffic based on an opened architecture. Therefore, they can barely serve the
current delay sensitive traffic based on some priority-based schemes but they will not be able to last
with the continuous growth of real-time applications, which flourish rapidly in the last few years. In
our researches, we, firstly, proposed a new packet-scheduling scheme for the wired networks which is
able to fulfill the tight delay constraints of the voice applications yet able to avoid service starvation for
traditional best effort traffic. We proved through mathematical analysis and simulations that the
proposed scheduler is more efficient than the current schemes, and then we showed that it can be easily
adopted to manage the network traffic congestion according to any network’s policies. Second, we
developed a new Voice Capacity estimation model for the Wireless LAN based on the clients’ spatial
distribution. Our model is not only more accurate than the existing models but it has also guided us to
introduce a new scheme for voice capacity enhancement without any extra resources allocation.
EJISST2008 June 8~10
118
EJISST-ID 146
Router- based Defense against DDoS Attack
Dalia Nashat and Susumu Horiguchi
Tohoku University
Assiut University
Email:dnashat@yahoo.com
The Internet infrastructure security has been gaining importance in recent years due to the growing
concerns for cyber-warfare. Router attack is one of the most devastating and least researched topic
among Internet Infrastructure attacks. Among all router attacks Distributed Denial of Service (DDoS)
attacks become serious threat since the SYN attacks flooded and shut down several Web servers in
September of 1996. The DDoS attacks are usually treated as a congestion control problem, because
most such congestion is caused by malicious hosts that do not obey traditional end to end congestion
control. Since the congestion problem must be handled by the routers, so new functions should be
added to routers to detect and preferentially drop packets that probably belong to an attack. In order to
achieve this approach, my research focusing on study the properties of DDoS attacks to develop a
comprehensive understanding of this attack and improve the available schemes for DDoS attack
detection by focusing on the low rate agent of DDoS attack to propose a router based detection scheme
for it. The extensive trace driven simulation results of my research indicate that the proposed router
based detection schemes can guarantee a very good sensitivity to DDoS attack and thus significantly
outperforms the current detection schemes in terms of detection probability and also average detection
time.
EJISST-ID 156
Two models for electro-magnetic wave amplifier utilizing traveling
electron beam
Hesham Fares Ahmed Hassan and Minoru Yamada
Kanazawa University
Assiut University
hesham@popto5.ec.t.kanazawa-u.ac.jp
The possibility to get unidirectional optical amplifier had theoretically proposed utilizing the traveling
electron beam and a high refractive index wave guide in vacuum. This amplifier should be applicable
from microwave region to X-ray region basing on same scheme. We proposed two types of analytical
model, one is named as Coherent Electron Wave Model (CEW-Model) and another model is Velocity
Modulated Model (VM-Model) to describe the optical amplification over a very wide frequency region
including THz region. In the first model, when the spreading length of a coherence electron wave is
much larger than EM-wavelength, quantum mechanical analysis is invoked based on the density matrix
formalism. The second model (when, the coherence length is smaller than the wavelength) corresponds
to the classical treatment, where electrons are spatially localized and whose velocity is modulated by
EM-wave. We also show the classical dynamics equation can be derived from quantum mechanical
analysis.
EJISST2008 June 8~10
119
EJISST-ID 163
A Dynamic Channel Assignment Problem for Wireless Internet-access
Mesh Networks
Walaa A. Hassan, Nobuo Funabiki and Toru Nakanishi
Okayama University
Cairo University
walaam99@yahoo.com
The wireless Internet-access mesh network (WIMNET) has been studied to realize a flexible,
inexpensive large-scale access network to the Internet. WIMNET is composed of multiple access points
(APs) as wireless routers that are communicated with each others through multihop wireless links
mainly by the wireless distribution system (WDS). In WIMNET, hosts may move in the field, which
can raise issues such as the quality of service, the channel interference, and the network load
management. As a result, the proper channel assignment to the wireless links between APs depending
on the network traffic, becomes essential to improve the performance of WIMNET by alleviating these
issues. At the same time, channel reassignments should be avoided to minimize the stop time of
network operations due to channel reassignments. In this paper, we formulate this dynamic channel
assignment problem for WIMNET as a combinatorial optimization problem, and present its heuristic
algorithm through modifications of our existing algorithm with the newly defined decision function for
the channel reassignment. The effectiveness of our approach is verified through extensive simulations
using our WIMNET simulator.
EJISST-ID 223
Automatic Building of New Field Association Word Candidates Using
Search Engine
Atlam ELsayed and Jun ichi Aoe
The University of Tokushima, Japan
Tanta University, Egypt
satlam@yahoo.com
With increasing popularity of the Internet and tremendous amount of on-line text, automatic document
classification is important for organizing huge amounts of data. Readers can know the subject of many
document fields by reading only some specific Field Association (FA) words. Document fields can be
decided efficiently if there are many FA words and frequency rate is high. The research in this paper
focuses on finding new FA words automatically. To do so, large quantity of documents data for
building FA word candidates are necessary. This paper presents a system for automatically building FA
words by adding new FA word candidates which change over time to the dictionary. This new system
uses a WWW search engine to extract FA word candidates from document data for each field. These
candidates are automatically compared with FA words already in a dictionary of FA words. Then, new
FA words can add to FA words dictionary. From the experiential results, our new system can
automatically appended around 44% of new FA words to the existence FA word Dictionary. Moreover,
the concentration ratio 0.9 is also effective for extracting relevant FA words that needed for the system
design to build FA words automatically. Section 2 introduces FA words, field systems, and FA levels.
Section 3 explains a system for automatically building new FA word candidates and explains document
collection. Section 4 introduces word collection data and experimental evaluation and considers the
efficiency of this system. Section 5 presents a conclusion and indicates possible future work.
EJISST2008 June 8~10
120
EJISST-ID 225
An Automatic Filtering Method for Field Association Words by Deleting
Unnecessary Words
Elmarhomy Ghada and Jun Ichi Aoe
The University of Tokushima, Japan
satlam@yahoo.com
Document classification and summarization are certainly important for document text retrieval.
Generally, human can recognize fields like <Sports> or <Politics> based on specific words called Field
Association (FA) words in that document fields. The traditional method causes misleading redundant
words (unnecessary words) to be registered because the quality of the resulting FA words depends on
learning data pre-classified by hand. Therefore, recall and precision of document classification degrade
if their classified fields by hand are ambiguous. This paper proposes two criteria: 1) deleting
unnecessary words with low frequency, 2) deleting unnecessary words using category information (part
of speech, prefix, suffix, morphological analysis and semantic primitive). Moreover, FA words
dictionary created by the traditional method can be filtered out by deleting unnecessary words from the
dictionary under proposed criteria. In order to verify the presented method, about 38,372 word
candidates are used for the experimental evaluation. Furthermore, Precision and F-Measure are
improved by 26% and 15% respectively, over the traditional method. Section 2 introduces a field tree
and FA words determination algorithm. Section 3 proposes a decision method for deleting unnecessary
words. Section 4 describes words collection data, experimental evaluation, and the effectiveness of the
presented method in terms of Precision and F-Measure. Section 5 presents a conclusion and indicates
possible future work.
EJISST-ID 007
Contents Aware Network Security for JPEG 2000 Encoded Images
Ayman Haggag and Takashi Yahagi
Chiba University
Helwan University
aymanhgg@gmail.com
Security of data exchanged over networks and data communication systems has always been a great
concern. While many network security techniques have been developed and used, security and flexible
handling of media, including adaptation, are traditionally conflicting goals, and security is often
incorporated in a media distribution system in a media-unaware manner. We examine how security
methods can be designed so that media aware protection can be used to simultaneously achieve end-toend security and flexible secure adaptive transcoding and mid-network adaptation of the protected
content. We focus on the security services of authentication and confidentiality, and describe the
techniques that make this possible. In our research, we propose a novel approach for applying
authentication to JPEG 2000 images in a scalable manner. Our authentication technique can be used for
source authentication, nonrepudiation and integrity verification for the received possibly transcoded
JPEG 2000 images in such a way that it is possible to authenticate different resolutions or different
qualities extracted or received from a JPEG 2000 encoded image. We also propose an access control
and scalable encryption technique for JPEG 2000 encoded images. In our proposal, we encrypt JPEG
2000 codestreams using the SNOW 2 progressive encryption algorithm to encrypt resolutions, quality
layers, or packets independently to provide resolution, quality or fine-grain scalability. Access is
controlled to different image resolutions or quality levels granted to different users receiving the same
encrypted JPEG 2000 codestream but having different decryption keys.
EJISST2008 June 8~10
121
EJISST-ID 037
Towards a novel all-optical switch, design, fabrication and
characterization
Salah A. Ibrahim and Yoshiaki Nakano
Research Center for Advanced Science and Technology, the University of Tokyo
Electronics Research Institute (ERI)
salah05@gmail.com
Optical high-capacity transmission systems are expected to rely on optical time division multiplexing.
For this kind of systems fast demultiplexers and cascadable switches with high extinction ratios are
required. All-optical devices have the potential to meet these requirements in which the all-optical
switches based on semiconductor optical amplifiers (SOA’s) play a central role. This work is focused
on studying and realizing a novel structure for the SOA-based all-optical switch and implementing it in
a monolithically integrated form. The conventional structure of the switch takes the form of a MachZehnder interferometer with an SOA located on each arm. In which the width of the used SOA is
selected to ensure its single-mode operation. In the novel structure, each SOA is designed as a
multimode interference (MMI) bar coupler. This is mainly proposed to separate the data signal from the
control signal as each of them is directed to a different port at the MMI-SOA output. Beside the
advantage of separating the control and data signals, the new structure is also characterized by its small
size as the element required to combine the data and control signals is merged with the nonlinear
element required for switching. The ongoing research includes numerical simulation to verify the
validity of the new idea, full design of the new switch elements, and the development of a suitable
fabrication process to fabricate the switch in which the selective area growth and the offset quantum
well methods are considered. As the switch is fabricated using dry etching, optimizing the etching
conditions for the inductively coupled plasma etching is a part of this work. Recently monolithicallyintegrable discrete active MMI's have been successfully fabricated and cross gain modulation (XGM)
between data and control signals inserted from different MMI ports have been experimentally
observed.
EJISST-ID 045
A method to improve the precision of search engines using Ranking of
Field Association terms using Co-word analysis
Mahmoud Rokaya, Elsayed Atlam, Masao Fuketa, and Jun-ichi Aoe
Tokushima University, Japan
Tanta University, Egypt
badee@is.tokushima-u.ac.jp
Information retrieval (IR) involves finding some desired information in a store of information or a
database. Co-word analysis aims at finding the relation between concepts, ideas and problems in a
specific discipline. This paper will present a method to find relations between Field Association terms
depending on Co-word analysis. Co-word analysis will be used to achieve a ranking of a selected
sample of FA terms. Based on this ranking a better arranging of search results can be achieved.
Experimental results achieved using 41 MB of data (7660 documents), from the experimental results,
the average number of relevant documents, among the first 50 documents, after applying the arranging
scheme was 34.92 documents whereas the average number was 29.92 before applying the arranging
scheme. The average precision increased by 18.3% after applying the proposed arranging scheme.
EJISST2008 June 8~10
122
EJISST-ID 136
Mutual Intention in Human Robot Teammate Situations
Yasser Mohammad and Toyoaki Nishida
Kyoto University
Assiut University
yasser@ii.ist.i.kyoto-u.ac.jp, nishida@i.kyoto-u.ac.jp
The main theme of this research is trying to build a robot that can form and maintain mutual intention
with humans. Mutual intention is defined as a state of the interaction in which a dynamic coherence of
the internal states and believes toward the interaction is maintained between the interaction partners.
The first step in this project was to explore the use of robot feedback for attenuation of noise signals on
human hand motion. This led to the creation of the Interactive Perception system used later in a
drawing system that proved to be more natural and effective than a traditional drawing system. The
second step involved analyzing nonverbal interaction between a human and a miniature robot which led
to interesting results regarding the consistency of gesture usage and evidence of human adaptation. The
same study showed that motion cues can serve as an effective and natural feedback mode for nonhumanoid robots. Currently my research project focuses in developing a humanoid that can learn
nonverbal interaction structure by utilizing recorded human-human interaction data in the form of a
hierarchy of dynamical systems, and then can adapt the learned architecture during actual interactions
with humans by utilizing elements of the theory of simulation. This interaction learning architecture
was tested on a synthetic agent simulation scenario and found effective in learning the underlying
processes responsible for the nonverbal behavior of the agents. In the future this algorithm will be
applied to human-robot interaction scenarios and its effectiveness will be evaluated.
EJISST2008 June 8~10
123
SESSION 14: Information & Communications Technology(ICT)
EJISST-ID 190
Decision Support System for Ubiquitous Learning Environments
Moushir M. El-Bishouty, Hiroaki Ogata and Yoneo Yano
The University of Tokushima, Japan
Mubarak City for Science and Technology, Egypt
moushir.elbishouty@gmail.com
Ubiquitous computing is a new information and communication technology that utilizes a large number
of cooperative small nodes with computing and/or communication capabilities such as handheld
terminals, smart mobile phones, sensor network nodes, contact-less smart cards, and RFID (Radio
Frequency Identification)..etc. In a ubiquitous learning environment, it is difficult for a learner to find
the right knowledge in time even if the source of this knowledge is very near to his physical location.
The aim of this research is to support the learners to make their own decisions based on the changed
context or sensor information. Therefore, we introduce a ubiquitous computing environment in order to
support the learners while doing tasks; this environment is called PERKAM (PERsonalized Knowledge
Awareness Map). PERKAM allows the learners to share knowledge, interact, collaborate, and
exchange individual experiences. It utilizes RFID tags to detect the surrounding physical space objects
then it generates the learners digital space where each object in the physical space has its corresponding
one in the digital space. On the other hand, the agent recommends the best matched educational
materials and peer helpers in accordance with the detected objects and the current location. This
environment provides the learner with Knowledge Awareness Map, which visualizes the space of the
environmental objects that surround the learner, the educational materials space, and the peer helpers
space.
EJISST-ID 092
Security Analysis of a Crypto-Compression Algorithm for Medical
Images
Osama Ouda and Yoichi Miyake
Chiba University
Mansoura University
oouda2002@yahoo.com
With the great advances in computer and network technologies in the recent years, digital images can
be copied and modified very easily. Therefore, image compression and encryption have become
necessary requirements when digital images is stored or transmitted over insecure channels. However,
compression and encryption operations are too expensive in terms of computation time. Recently, the
notion of selective encryption was introduced in order to decrease the amount of time required to
encrypt large images. Selective encryption techniques encrypt some parts of the image rather than
encrypting the whole image as in full encryption techniques. The problem of selective encryption
methods is that they do not achieve high security levels compared to full encryption methods. In this
paper, the security of a recent proposed selective encryption algorithm for crypto-compression of
medical images is analyzed. Based on the given analyses, some modifications are proposed to enhance
the performance of the investigated crypto-compression system.
EJISST2008 June 8~10
124
EJISST-ID 093
An Intelligent Recommender System Using Particle Swarm Optimizer
(PSO) and Artificial Immune System (AIS)
Amira abdel wahab ahmed and Shingo Kuroiwa
Chiba University
Menoufia University
amiraahmed_1@yahoo.com
With a large amount of digital data, the recommender system has proved to be very useful for the seller
and the buyer as well in many different applications specially in electronic commerce, books, and
movies and so on. It recommends goods for buyers according to their previous preferences and enables
them to share opinions with others to benefit from their experience. So The proposed work is
constructing a hybrid intelligent recommender system using artificial immune system (AIS) and
particle swarm optimizer (PSO).Using artificial immune system (AIS) method enhances the matching
of user needs with previous ones and others preferences. So AIS makes recommendations more
effective. In addition, The particle swarm optimizer (PSO) is used with AIS to improve the efficiency
of the AIS because PSO decreases the overall time required for matching and recommendations.
Therefore the proposed recommender system will inherent the characteristics of both algorithms and
provides the users with accurate recommendations in minimum time
EJISST-ID 094
An Intelligent Framework for Image Understanding
Ahmed zaher Mohamed Afifi and Yoichi MIYAKE
Chiba University
Menoufia University
ahmedza1980@yahoo.com
The segmentation process is very important for the image interpretation tasks and the result of image
segmentation is greatly affecting the result of overall interpretation process. So in this study we propose
a novel image segmentation technique that can be used as a common computer vision task. The
proposed technique utilizes a fast object oriented case-based reasoning for the selection of
segmentation parameters. The proposed system deals with the segmentation problem as an optimization
problem to find the optimal parameters for the segmentation algorithm using the Particle Swarm
Optimization. In addition, the system builds the CBR from these parameters and the features that
extracted from the image and when a new image is given to the system it is locates the suitable
parameters for it and if it is not locate a suitable case, it segments the image offline and store its
parameters.
EJISST2008 June 8~10
125
EJISST-ID 106
Participation Enhancement in Urban Planning, Decision-Making Process
Using Virtual Reality Techniques
Hatem Mahmoud Fathy and Takafumi Arima
Kyushu University
South Valley University
Hatem3us@hotmail.com
The urban environment is composed of elements; nothing of them is experienced by itself, but
integrates with each other, therefore, in planning projects we must deal with any of these elements as a
single unit. The planners and designers face difficulty in delivering their ideas to nonprofessional
customers and administrators to make them imagine the development of idea fully. Because the ability
to rapidly sketch and visualize design ideas is an important task in urban design, therefore planners
turned to make digital models on the computer for their projects. In recent years, the Virtual Reality
(VR) techniques have rapidly grown and received great media attention. By building VR models with
their increasingly dynamic interactive and experiential characteristics, one becomes able to simulate
real environment with various degree of realism. These techniques give us a great ability to control the
idea proposed, and add any object in real time. Now users, designers and administrators could imagine
the proposed project very easily, postulate opinions, and propose modifications in order to reach better
decision-making regarding the proposed project. The study aims to examine the visual quality of
building an interactive environment utilizing Virtual Reality tools, as well as any other benefits of
using such techniques to designers, planners, users and decision-makers. We realized the study goals
by building an interactive environment in Virtual Reality software called Virtools Dev. The target area
was a plaza in central area in the new campus for Kyushu University (Ito Campus).
EJISST-ID 109
Reconstruction algorithms for tomographic imaging
Essam A. Rashed and Hiroyuki Kudo
University of Tsukuba
Suez Canal University
essam@imagelab.cs.tsukuba.ac.jp
According to the recent reports published by the National Cancer Institute, Egypt has about 3,491,875
citizens who suffer from a cancer with 48 % incidence under the age of 20 (1999-2001). This huge
number of the patients which increased rapidly required an effective screening and diagnosis systems.
PET (Positron Emission Tomography) scanners are used to produce images of the function of human
body especially the activity of the cancer cells. The main target of my research is to develop new image
reconstruction algorithms for tomographic imaging including PET. In these algorithms, we focus on the
cases where only a small Region-of-Interest (ROI) is required to be imaged. Moreover, the developed
algorithms consider the cases where the measured projection data is incomplete (i.e. truncated). Two
algorithms have been already developed. In the first algorithm, we have succeeded in reducing the
computation time when a limited region of the patient is required to be reconstructed. In the second
algorithm, the image quality is improved when the measured data is truncated and incomplete
knowledge the object support is available.
EJISST2008 June 8~10
126
EJISST-ID 115
Load Voltage Regulation and Line Loss Minimization of Loop
Distribution System Using UPFC
Mahmoud Abdelnaby Sayed Abdallah
Nagoya Institute of Technology
South Valley University
modysss@yahoo.com.
Distribution networks may be classified as a radial or loop systems. The loop system is often preferred
to the conventional radial distribution system as it is widely considered as a good method for reducing
the power losses and the customer outages. Also, loop system increases the transmission capacity and
the power quality of the distribution networks. This paper presents a new method for achieving Total
line loss minimization and load voltage regulation in the loop distribution systems simultaneously.
First, an elaborated mathematical analysis of the total line loss minimum conditions in the loop
distribution systems is presented. Then, voltage regulation of the receiving end voltage is applied in the
loop distribution system under total line loss minimization condition. In order to achieve these two
objectives simultaneously, the unified power flow controller (UPFC), a typical FACTS (flexible AC
transmission systems) device that is capable of instantaneous control of transmission and distribution
power flow, is used. Also, the proposed control schemes of the UPFC series and shunt converters are
presented. The effectiveness of the proposed control schemes of the UPFC have been verified
experimentally using laboratory prototype in a 200V, 6 kVA system.
EJISST-ID 116
Automatic Human Body Modeling for Vision-Based Motion Capture
Ibrahim Hemdan and Kenji Terada
Tokushima University
ibrahim2010ing@yahoo.com
In recent years, because CCD cameras have become inexpensive and ever more prevalent, there has
been increasing interest in modelling human shape and motion from acquired image data. Such ability
has many applications, such as entertainment, sports medicine/athletic training, and biometry. This,
however, is an inherently difficult task, both because the body is very complex and because the data
that can be extracted from images is often incomplete, noisy and ambiguous. Introducing a valid model
is therefore one important practical step towards restricting motion tracking and surface measurement
algorithm for human motions and configurations. Our Goal is to model and to initialize an Automatic
Human Body Model for Human motion capture. Currently, a common practice of vision-based works
is to overcome this problem using manual annotation
EJISST-ID 071
Face Recognition under varying illumination using self-organizing Map
Saleh Aly and Rin-Ichiro Taniguchi
Kyushu University, Japan
South Valley University, Egypt
aly@limu.is.kyushu-u.ac.jp
Important practical applications of automatic face recognition have made it a very popular research
area in the last three decades. In spite of the expanding research in the field of face recognition, many
problems are still unsolved. Recently, many researchers focus on robust face recognition, which is
invariant to pose, expression, illumination variations. Illumination variation is still a challenging
EJISST2008 June 8~10
127
problem in the research area of face recognition especially for appearance-based methods. Selforganizing map (SOM) is a well-known and quite widely used neural network model that learns the
distribution of patterns in an unsupervised way. A pattern is projected from an input space to a position
in the map where the information is coded as the location of the activated or winning neuron. The SOM
is unlike most classification or clustering techniques in that it provides a topological ordering of
classes. Similarity in the input space is preserved in the output space. The topological preservation of
the SOM process makes it especially useful in the classification of data, which includes a large number
of classes. This paper focuses on the appropriate metric choice for face recognition using SOM; this
metric should be robust to illumination variation. The distance most commonly used in SOM learning
algorithm is the Euclidean distance that considers each observation dimension with the same
significance whatever the observation distribution inside classes. Clearly, if the data set variances are
not uniform, Mahalanobis distance is more appropriate than Euclidean distance. Results show that
Mahalanobis distance is more robust for illumination changes than Euclidean distance.
EJISST-ID 269
Architecture and Synthesis of a Two-Fingered Micro-Nano Hybrid
Manipulator
Ahmed A. Ramadan and Tatsuo Arai
Osaka University, Japan
Tanta University, Egypt
ramadan@arai-lab.sys.es.osaka-u.ac.jp
This paper presents the architecture of a new compact yet economical two-fingered micro-nano hybrid
hand. The hybrid manipulator hand consists of two parallel modules, upper and lower, connected in
series. Each module consists of a parallel kinematics chain with a glass pipette of 1mm diameter,
tapered to very sharp end, as an end effector. It is driven by three piezo-electric actuators in the three
legs of the kinematics chain. Each leg of the kinematics chain has the structure of Prismatic – Revolute
– Spherical (PRS) joint structure. As the length of the glass pipette end effector is decreased, the
accuracy of the micro-nano hand is increased. For long lengths of glass pipette end effector, this
manipulator works as micro-manipulator and as nano-manipulator for short lengths. A new solution for
the inverse kinematics problem of the total mechanism is obtained. Based on this solution, a simulation
program is developed to optimally choose the design parameters for maximum workspace volume. A
proposed Computer Aided Design (CAD) model based on optimal parameters is built and realized.
Also the system hardware setup of the micro-nano hand and its calibration process to get practical
jacobian inverse matrices are presented.
EJISST-ID 089
Blind image and video super-resolution based on mixed-norm
Osam A. Omer and Toshihisa Tanaka
Tokyo University of Agriculture and Technology
South Valley University
osama@sip.tuat.ac.jp
Super-resolution (SR) is an approach to obtain high-resolution (HR) image(s) from a set of lowresolution (LR) images. The most important steps of SR algorithms are image registration, data fusion,
and restoration. Image registration, is the process to align images (frames) to the reference image
(frame). Data fusion is the process which fuses the registered images onto HR grid. Restoration is the
process to estimate the HR image from the fused data on the HR grid. In this work, we address
problems of conventional SR methods having the following limitations. First, most of the existing SR
algorithms can not cope with local motions and hence not suitable for video sequences. Second, the
blurring operator is assumed to be known in advance and constant for all the LR images. Finally, SR
noise is assumed to be either Gaussian or Laplacian. To solve these problems, we propose a general
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cost function that consists of weighted L1- and L2-norms considering the SR noise model where the
weights are generated from the error of registration and penalize parts that are inaccurately registered.
Both the super-resolved images and blurring operators are jointly estimated. The objective and
subjective results are shown to demonstrate the effectiveness of the proposed algorithm.
EJISST-ID 221
Earthquake Onset Detection using Spectro-Ratio on Multi-Threshold
Time-Frequency Sub-Band
Ali G. Hafez and T. Kohda
Kyushu University
National Research Institute of Astronomy and Geophysics
aligamal@kairo.csce.kyushu-u.ac.jp, kohda@csce.kyushu-u.ac.jp
Automatic onset detection and picking algorithm has been proposed by applying the spectro-ratio on
time-frequency sub-band. Automatic onset picking is of great importance in event location, event
identification, acquisition of triggered seismic data, and source mechanism analysis. Various
algorithms have been proposed for automatic detection of onset arrivals. Although many trigger
algorithms had been proposed, they are rarely used in the seismic data loggers currently in the market.
The sophisticated adjustments of operational parameters to actual signals and seismic noise conditions
at each seismic site had shown large error in practice. The proposed algorithm does not need any
parameter settings as it will work on data generated by any kind of seismometer either short or very
broad band seismometer. In our proposed algorithm, powers of frequency sub-bands are determined by
spectrogram as a time-frequency representation. Adaptive thresholds are calculated for one of these
sub-bands to check if there is a p-wave arrival in the segment or not. To verify this check another test is
done using the spectro-ratio. The major advantages of the proposed algorithm are as follows: The
signal to noise ratio (SNR) is improved as noise power of the selected sub band is much weaker than pwave power. Thresholds for the selected sub-band are adaptive as they are calculated at beginning of
each segment. Adaptive threshold setting enables us to detect the p-wave arrival in presence of seismic
noise which has a changing behavior. Our algorithm is applied on local events from Cairo region
recorded by three stations of the Egyptian National Seismic Network (ENSN). Maximum standard
deviation is observed to be 0.113 seconds of the corresponding manual picks made by analysts.
EJISST-ID 239
Multiple Object Tracking Using Local PCA
Ali F. Soliman and K. Terada
Tokushima University
Menoufia University
aly_soliman@yahoo.com
Tracking multiple interacting objects represents a challenging area in computer vision. The tracking
problem in general can be formulated as the task of recovering the spatio-temporal trajectories for an
unknown number of objects appearing and disappearing at arbitrary times. Observations are noisy, their
origin is unknown, generated by true detections or false alarms. Data association and the estimation of
object states are two crucial tasks to be solved in this context. This work describes a novel,
computationally efficient tracking approach to generate consistent trajectories. First, trajectory
segments are created by analyzing the spatio-temporal data distribution using local principal
component analysis. Subsequently, linking between trajectory segments is carried out relying on spatial
proximity and kinematic smoothness constraints. Tracking results are demonstrated in the context of
human tracking and compared to results of a frame-to-frame-based tracking approach.
EJISST2008 June 8~10
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EJISST-ID 242
Similarity Measurement Approaches Using Association Keywords
Mahmoud Elmarhomy and Fuji Ren
The University of Tokushima, Japan
satlam@yahoo.com
Conventional approaches to text analysis and information retrieval which measured document
similarity by using considering all of the information in texts are a relatively inefficiency for processing
large text collections in heterogeneous subject areas. This paper outlined a new text manipulation
system FA-Sim that is useful for retrieving information in large heterogeneous texts and for
recognizing content similarity in text excerpts. FA-Sim is based on flexible text matching procedures
carried out in various contexts and various field ranks. FA-Sim measures texts similarity by using
specific Field Association (FA) terms instead of by comparing all text information. Similarity between
texts is faster and higher by using FA-Sim than other two analysis methods. Therefore, Recall and
Precision significantly improved by 39% 37% over these two traditional methods. Section 2 of this
paper identifies simple FA terms, provides document field trees and discusses how FA terms can be
found electronically by determining FA terms levels algorithm. Section 3 introduces a procedure for
indexing FA terms automatically and how to calculate term weights. Section 4 introduces pairwise
document similarities and identifies similarity measurement by combing a Vector-Space model with
FA-Sim. Section 5 describes FA-Sim algorithm and compares FA-Sim method with Word Form and
Word Stem methods using Recall and Precision to measure average similarity. Also, section 5 verifies
FA-Sim using 38,000 articles on various topics from a data set of 20 Newsgroups from CNN Web Site
(1995-2001) and a large English Penn-Treebank Corpus. Section 6 concludes with an indication of
possible future work.
EJISST-ID 244
A new Algorithm based on Geometric Analysis for Task Scheduling in
Multiprocessor systems
Hassan Youness, Masaharu Imai, Abd_Elmonem Wahdan,
Mohammed Moness and Ashraf Salem
Osaka University
Minia University
y-hassan@ist.osaka-u.ac.jp
Parallel applications can take the advantage of parallelism only when their parts do not wait for data
longer than necessary. The appropriate scheduling strategies control the execution of the parallel
application modules. In this paper, we proposed a new scheduling algorithm based on geometry
analysis for the Task Precedence Graphs and A-star (Artificial Intelligence Algorithm) to produce an
optimal solution for the allocation/scheduling problem of parallel applications to parallel and
multiprocessor architecture referred to as ASIP Array Systems. The main goal of this work is to
significantly reduce the search space for the optimality and also guarantee the optimality due to the
analysis of task graphs geometry and using pruning methods. The Algorithm is implemented on a
general task graph problems that are manipulated in most of works and obtain the optimal scheduling
with a little number for the search space of states. The proposed algorithm reduced the search space by
at least 55%. Some examples are used to demonstrate the viability and potential of the proposed
algorithm.
EJISST2008 June 8~10
130
EJISST-ID 252
Computer-Aided Diagnosis System for Liver Cancer Using Multi Slice
CT images
Ahmed Shawky Mohamed Maklad and Noboru NIKI
The University of Tokushima
ahmak04@yahoo.com
At liver transplantations and surgery, hepatic blood vessels detection can help surgeons to identify
places of the hepatic blood vessel and gather them in a right way. Hepatic blood vessel system is one of
the most complicated systems in the human body. A manual detection of the hepatic blood vessels is
available, but it is time consuming and error prone. In this paper, the hepatic blood vessel system is
presented by using raw contrast enhancement multi slice CT images. That detection depends on
comparison of hepatic blood vessel at multi phases. Detection of hepatic blood vessel starts with
manual detection of it from multi slice CT images. Then its auto-detection is done. It is aimed at
detection of 3D images of the hepatic blood vessels at different phases as much as possible. Those
images can help radiologists at different analysis and surgeons at hepatic surgical operations. A
comparison between manual and automatic detections has been held to evaluate the auto-detection
results.
EJISST-ID 256
Video Coding Using Motion Estimation and Compensation Techniques
Mohamed Ghoneim, Norimichi Tsumura and Yoichi Miyake
Chiba University
Mansoura University
mghoneim@graduate.chiba-u.jp
Motion estimation has played an important role in some video coding and processing techniques. One
popular technique for motion estimation, as recommended in both MPEG and H.26x standards, is the
block matching algorithm. The main idea of block matching algorithm is to divide images into blocks
and then find the best match block in the previous frame for each block in the current frame for a given
matching criterion. We observed the performance of different motion search algorithms within the
motion estimator. This approach will allow us to consider the motion search algorithms in two different
ways:1) In terms of the prediction error variance, this is indicative of the entropy of the resulting
information, 2) In terms of overall encoder performance, this considers how the motion search
performs in different video coding systems. Our study is based on computational complexity,
compression ratio, and video fidelity. We introduce a new block matching search algorithm which is
proved to be efficient and fast compared to well known search algorithm.
EJISST2008 June 8~10
131
EJISST-ID 276
Efficient Face Detection and Recognition System
M. Hassaballah and Shun IDO
Ehime University, Japan
South Valley University, Egypt
m.hassaballah@ic.cs.ehime-u.ac.jp , ido@cs.ehime-u.ac.jp
Face detection is the first step of any face processing system. Effective methods of face detection and
localization are especially needed in human identification and verification systems which are more and
more commonly installed in public places, such as; airports, railway and subway stations, and market
centers. Precise and accurate determination of face area and also face features, e.g., eyes, mouth and
nose, plays key role in this kind of applications, because it is initial step in face recognition. This task
however, is so complicated because of orientation, scaling, rotation, illumination, etc. which are present
in most images. Even to the same people, the images taken in different surroundings may be unlike.
Additionally, faces in images are in many situations partially occluded by glasses, headgears, chins or
other obstacles. All these factors have important impact on efficiency of face localization methods.
Face recognition in an unconstrained daily life environment without the user’s cooperation (e.g. for
recognizing someone in an airport) is currently a challenging task. Many years’ effort is required to
produce practical solutions to such problems. In this study we are trying to design and implement an
efficient and robust automatic face recognition system for access control applications which can be
used to access to a building, a laboratory or equipment, taking into account that the proposed system
should have these properties; fast enough to do real-time detection, able to deal with faces of different
poses, and have a low false detection rate. In this context we will try to pick up the feature points which
represent the most important characteristics on the face and can be extracted easily. The number of the
feature points should take enough information and not be too many; at least 9 feature points that have
the property of angle invariance will be located, including 2 eyeballs, 4 near and far corners of eyes, the
midpoint of nostrils and 2 mouth corners. Our system will be tested using most famous databases such
as FERET, ORL, BioID, or UMIST Face Database.
EJISST-ID 307
Automatic Text categorization for Arabic Documents
Walaa Aly and Seiichi Uchida
Kyushu University, Japan.
South Valley University, Egypt
walaa_ata@yahoo.com
Automatic Text categorization (ATC), the assignment of text document to one of the predefined
categories based on its contents, has a grown interest in the last years, due to the wide spread of the
textual information on the Internet. Consequently, there are many researches dealing with this problem.
In the past, categorization was done manually; a classifier was defined manually by domain experts,
but nowadays, it is done automatically. A classifier is constructed by learning from a set of preclassified documents the characteristics of the categories. Obviously, there are many advantages of the
second approach over the first one. ATC is more effective since it can be constructed and updated easy,
can save the expert labor power, and can save cost and time. Although there is a lot of work done for
the text categorization for English documents, a little work has been done for Arabic documents. This
is due to the complexity of Arabic language. This fact motivated the work on automatic Arabic text
categorization. It proposes a system based on normalization, stop-words removal, and document
stemming. The system was successfully designed, implemented, and tested. The tested database
consists of 1500 documents, three hundred for each of 5 categories obtained from Aljazeera web site.
In addition, a list of keywords for each category was generated and stored. Standard performance
measures were applied. Despite the complexity of Arabic language, the system shows very significant
results.
EJISST2008 June 8~10
132
EJISST-ID 293
A STUDY FOR AUTOMATED VISUAL INSPECTION OF TEXTILE
MATERIALS BY IMAGE PROCESSING
Khaled Issa and Hiroshi Nagahashi
Tokyo Institute of Technology
Beni-Suif University
{khaled,longb}@isl.titech.ac.jp
This research presents cases study of the development, implementation and performance analysis of an
automated visual inspection method for textile materials properties in the presence of noise. The
present work proposed a new concept of segmentation of non uniform noisy images by using logGabor filter and applying a modified active contour method based on image gradient and mean
curvature technique. A common problem in the splice inspection is the grading of the splice joint, since
manual grading can be erroneous. Further, the grading depends on the experience of the person. A
dynamic time warping based approach for splice joint classification is introduced. This approach
depends on the degree of matching between the splice part and the non spliced part of the same yarn.
Using dynamic time warping in this context is also a novel scientific contribution. Moreover, the
segmentation system presented in this study is used for detection of different defects in the fabric.
EJISST2008 June 8~10
133
SESSION 15: Civil and Environmental Engineering-Earthquake
Geotechnical, and Air Pollution
EJISST-ID 079
DESIGN AND CONSTRUCTION CHALLENGES OF LONG SPAN BRIDGES
CONCEPT IN EGYPT
Shehata E. Abdel Raheem and Toshiro Hayashikawa
Hokkaido University, Japan
Assiut University, Egypt
shehataraheem@yahoo.com
Long span bridges represent a special, critical class of construction in terms of their value and impact
of their performance on the economic well-being of major metropolitan areas. In the field of long-span
bridges, the Akashi Kaikyo suspension bridge and the Tatara cable-stayed bridge of the HonshuShikoku bridges are the world’s longest suspension and cable-stayed bridges, respectively. In addition,
many other bridges are listed among the world’s long-span bridges, indicating that Japanese long-span
bridge technology now ranks high among the world. The principal challenge for using long span
concept in Egypt is to provide an economical structure, capable of being constructed using materials
and methods suited to Egypt. Particular attention should therefore be given to develop simple structural
solutions and components, using where possible materials which can be easily obtained locally. In
addition a construction method should be developed using locally available equipment and techniques.
Owners and bridge engineers are challenged to design and construct long span bridges but they often
lack the training and experience needed to be successful. Among the specific issues that enter into
long-span bridges are: Aesthetics, Long-span bridges are signature structures, tend to dominate the
local landscape, so the appearance should be carefully considered for harmony with the environment.
Serviceability, it is important to design a bridge that will not require constant maintenance to keep it in
service. Constructability, the large investment in materials and the equipment, temporary works and
labor required to construct long-span bridges, it is imperative that constructability be considered during
design.
EJISST-ID 157
High Performance Ferrocement-Grouted Mortar Composites for
Sustainable Development of Construction Materials
Mahmoud A. WAFA and Kimio FUKUZAWA
Ibaraki University, Japan
South Valley University, Egypt
mwafam4@yahoo.com
Currently, Egypt-Japan is taking strong steps in building a strong scientific base of scientists in every
field of modern sciences and technology. Within the important fields of modern sciences and
technology, researchers should gain various knowledge’s; one of the most important cores of the
modern sciences and technology is a sustainable development of construction materials. Sustainability
generally means having no net negative impact on the environment. The sustainable development of
construction materials creates the environment for a new and widely spread science and is considered
as one that is constructed for the total environmental impact during the entire lifetime, including the use
of the construction materials, is reduced to a minimum. The lifetime of the structure has a direct impact
on sustainability. When the structure deteriorates, it must be destructed and rebuilt. The lifetime is
directly controlled by the durability of the construction materials. This paper focuses on the high
performance ferrocement-grouted mortar composites, tailored for “greener” performance, and has
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applied to the structure application for improving the sustainability. Ferrocement is ideally suited for
thin structural elements because of the uniform distribution and dispersion of reinforcement, which
provides higher durability and tensile strength. Therefore, the main objective of the present paper is to
generally amplify our knowledge of the high performance ferrocement-grouted mortar composites for
sustainable development of construction materials. The results clarify that the use of high performance
ferrocement-grouted mortar composites considerably improves the sustainable development of
construction materials. Consequently, the ferrocement-grouted mortar composites are considered as a
promising construction materials solution to the global structure deterioration problem and tensile
ductility are the most important properties of these types of composites.
EJISST-ID 177
Innovative Design of Calibration Chamber for Geotechnical Physical
Modeling
Adel M. El-Kelesh and Ken-ichi Tokida
Osaka University, Japan
Zagazig University, Egypt
adkelesh@yahoo.com
Calibration chambers have been developed and used mostly to establish correlations between different
soil parameters and the results of in-situ penetration devices and to physically model and investigate
other problems, such as chemical grouting and fracture grouting. Testing under controlled conditions is
the great advantage of calibration chambers. The first part of this paper discusses limitations of the
available chambers in simulating the in-situ conditions and describes the design and testing procedure
of a calibration chamber recently developed to physically model and investigate various geotechnical
problems. The chamber which has been developed is of the double-wall type and can independently
control the sample stresses and deformations and impose the K 0-condition and different boundary
conditions. Compared to the available largest double-wall chambers, the developed chamber has
several innovative features that provide for a better simulation of the in-situ conditions. It is larger in
size (encloses samples of 1.40 m in diameter and 1.45 m in height) and self-reacting, allows for larger
compression of the sample, applies the vertical stress at the top of sample, provides for a rigid
boundary at the sample base and provides for upheave of the sample surface. The second part of the
paper describes the use of the developed chamber to physically model two grouting techniques:
compaction grouting and TGC grouting. Typical results of consolidation and injections into sand
samples are presented. The presented results reveal perfect performance of the chamber in terms of the
sensitivity to small pressures and deformations and the control of boundary conditions. These results
are also discussed to illustrate the corresponding grouting mechanisms in terms of the variation with
injection of the injection pressure and the soil stresses and deformations.
EJISST-ID 270
Groundwater seepage into an abandoned mining site in Egypt
Amgad Salama, T. Esaki
Kyushu University, Japan
Atomic Energy Authority, Egypt
asalama@doc.kyushu-u.ac.jp
Groundwater seepage into a former mining site in Egypt is proposed for simulation. This site was used
for Basalt extraction. After the mining activities had stopped a large open pit was left over. The pit has
a dimension of approximately 1200 x 600 x 30 m. After the pumping operation had ceased to work,
groundwater seeped into the pit forming a lake. If this lake is left unprotected, it can easily get polluted.
With any fluctuation in the head of the underneath groundwater reservoir water from the lake may seep
back into groundwater. If this water is polluted, groundwater reservoir will eventually get polluted too.
Unfortunately, no data are available that may shed light on the source of this water, i.e., whether it is
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from a confined or an unconfined aquifers. Several scenarios may be hypothesized to explain the filling
of these open pits with water. That is in one scenario, water may be proposed to have seeped into the
open pit from an underneath confined aquifer through fractures in the host rock while in another
scenario water may have seeped from the nearby fresh water canal again trough fractures in the host
rock. In either of these scenarios two possibilities may be found, the first of which is based on the
assumption that there may exit a set of discrete fractures or that the fractures are so intense that one
may assume an equivalent porous media scenario. In both scenarios, the time required to fill up the
open pit with water will be the determining factor in supporting one scenario over the other. In this
work the discrete fractures model is studied. It was found that the set of discrete fractures was
insufficient to fill up the lake in the actual time span.
EJISST-ID 273
Evaluation of Geo-environmental Impact for the Application of Industrial
Waste Materials in Geotechnical Problems
Ahmed A. and Keizo Ugai
Gunma University
Beni-Suef University
aly_76@hotmail.com
The main goal of this research is to investigate the feasibility of using various industrial waste materials
already existing in Japan and Egypt, as replacement enhancement materials in geotechnical problems
especially in soil stabilization area. It is clear the application of industrial waste in civil engineering
fields is very important to keep environmental against pollution, cut off the cost of disposal elimination
and minimize the cost of enhancement material that are used in problematic soils. The effect of using
such industrial waste material on geo-environmental conditions is proposed to meet sound
environmental. The durability of using such materials against surrounding environmental is considered.
EJISST-ID 059
Geophysical Structures of Several Geothermal Fields in Egypt and
Conceptual, Numerical Models of Their Geothermal System
Mohamed Abdel Zaher and Sachio Ehara
Kyushu University, Japan
National Research Institute of Astronomy and Geophysics, Egypt
moh_zaher@yahoo.com
Although Egypt is not characterized by abundant Cenozoic igneous activity, its location in the
northeastern corner of the African plate suggests that it may possess geothermal resources, especially
along its eastern margin. The eastern shore of the Gulf of Suez consists of the hottest springs such as
Uyun Musa and Ain Hammam Faraun. These areas along both shores of the Gulf of Suez are the most
promising for geothermal development. Additionally, in Eastern Desert of Egypt particularly the areas
adjacent to the Red Sea, some geothermal potential fields were located. In the western part of Egypt
(Western Desert) the major oases (Kharga, Dakhla, Farafra, and Bahariya) have low regional
temperature gradient but many wells which drilled deep artesian aquifers show a low temperature
geothermal resource (35-40oC range). Many geothermal explorations were carried in Egypt using
geophysical and geochemical techniques. The recent data indicate that temperature of 150oC or higher
may be found in the reservoir located adjacent to Gulf of Suez and Red Sea coastal zone. Conceptual
and numerical models were made in Hammam Faraun hot spring located at the western side of Gulf of
Suez, which represent the hottest spring in Egypt. The models show that the heat source of the hot
spring is probably derived from high heat flow and deep circulation controlled by faults associated with
the opening of the Red Sea and Gulf of Suez rifts.
EJISST2008 June 8~10
136
EJISST-ID 063
Chemical compounds effect on critical shear stress and erodability of
volcanic ash soil
Islam Mamdouh Awad and Noriyuki Yasufuku
Kyushu University
Alexandria University
ismamdouh@yahoo.com
Runoff flow erosion is frequently observed for the volcanic ash sandy soil located in Kagoshima area,
south western Japan. Worldwide, it is becoming more important to predict the hydraulic erosion
amounts depending on the soil mechanical properties to facilitate the method to detect the areas more
vulnerable and subjected to erosion. This research presented the peak compressive strength as a main
soil property to predict the soil critical shear stress and thus to calculate the erosion rates. However,
only a few studies have documented the relationship between soil mechanical properties and critical
shear stress, and the results obtained have sometimes seemed contradictory. That is why this research
had an aim to overcome these difficulties by using a new laboratory sophisticated erosion model. A
series of physical model tests were performed with a wide range of variability of parameters such as
chemical compounds conditions, degree of compaction, flow rates and soil mechanical properties, to
allow predicting a reliable trend for the critical shear stresses and erosion rates with the peak
compressive strengths with a limited tolerance margin. The results show a significant correlation
between these parameters. On the other hand, the results proved a remarkable improvement for soil
ultimate strength with the common use of chemical compounds doses. The results show that the
calcium hydroxide offers a better soil improvement rather than the calcium oxide with a trend of
40%~60% limitation of soil erosion rates, 4~5 times improvement in soil peak compressive strength,
and a risen critical shear stress from 5Pa to 8.8 Pa. These results could then provide important findings
to predict runoff flow erosion from a geotechnical point of view and thus facilitate field measurement
erosion prediction for the volcanic soils.
EJISST-ID 084
Numerical Simulation of Debonding Failure of Reinforced Concrete
Beam Strengthened with Externally Bonded FRP and Development of
Rational Prediction Method
Khalid Farah and Yasuhiko Sato
Hokkaido University
South Valley University
drkhalid_farah@yahoo.com
Extending the service life of the existing reinforced concrete (RC) structures is one of the major tasks
of the civil engineering. Strengthening the RC beams by using fiber reinforced polymers (FRP) sheet or
plate as externally bonded by using epoxy resin is one the best techniques that had been appeared
recently due to the superior characteristic of the FRP. The flexural strength of RC beams can be easily
enhanced by using externally bonding FRP sheet or plate to their tension side. The strengthened RC
beam by externally bonded FRP reaches the ultimate state with the following failure modes
corresponding to the reinforcing volume and length of the FRP such as: (1) FRP rupture; (2) crushing
of compressive concrete; (3) shear failure; (4) concrete cover separation; (5) plate end interfacial
debonding; and (6) intermediate crack induced (IC) debonding. The first three failure modes identified
earlier are similar to those in conventional RC beams. The last two modes of the above mentioned
failure modes, (5 and 6) are unique to plated beams and are referred to as debonding failures which
generally occur before the maximum moment capacity or shear capacity of the plated beam section is
reached. It is obvious that much less attention has been paid to numerical studies of debonding
mechanism in comparison to the wealth of experimental investigations. So this study is devoted to
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develop a numerical simulation method by using rigid body spring model (RBSM) to evaluate the
debonding failure of RC beams strengthened with externally bonded FRP.
EJISST-ID 121
Advanced bifurcation analysis of truss structures
Manar Ahmed and Kiyohiro Ikeda
Tohoku University
Assiut University
Manar_ahmed1@yahoo.com
Truss structures such as dome and shell are constructed to have symmetric geometric configurations
and stiffness distributions. However, perfect symmetry in reality cannot be realized due to the
unavoidable presence of initial imperfections in various properties, including loading pattern vectors,
nodal initial position vectors, initial member length, cross-sectional area and Young's modulus of
structural members. Although imperfections in general are never so large as to apparently affect their
configurations, they degrade drastically the load-bearing capacities of the structures at the onset of
bifurcation buckling. The concept of imperfection sensitivity has revealed that initial imperfections
cause such degradation. The influence of the magnitude of imperfections on the load-bearing capacities
of such structures can be evaluated by means of this concept. Sensitivity analysis for singular state has
sub-branches that are dependent on whether the singular state is associated with a limit point, a simple
bifurcation point, a coincident critical point, and so on. In the design of structures undergoing buckling,
it is preferable to consider the “worst” imperfection that reduces the load-bearing capacity most
rapidly. Various techniques have been proposed to determine such critical imperfections. Initial
imperfections of structures that may entail significant reduction in buckling strength are subject to a
probabilistic variation. The study of initial imperfections, accordingly, has to be combined with
probabilistic treatment to make it practical. In the theoretical development, the imperfection sensitivity
law by Koiter played an important role. This law was used as a transfer function from an initial
imperfection to the deterministic critical load and, in turn, to obtain the probabilistic variation of
critical load for an imperfection with a known probabilistic property. This framework was extended to
a number of imperfection parameters to deal with the worst imperfection and the probability density
function of critical loads for random initial imperfections in an asymptotic manner.
EJISST-ID 134
Borehole ground penetrating radar technique for subsurface fracture
characterization and its application to geothermal energy extraction
Khamis Kabeel Ali Mansour and Motoyuki Sato
Tohoku University
Research Institute of Astronomy and Geophysics
kham123@hotmail.com
During this period Egypt starts to suffer from lacking in energy resource like oil and gas that urge us to
think of others energy resources in our country. One of these resources is geothermal energy which is
not effectively explored until now in Egypt. GPR is a geophysical technique that uses the reflection of
electromagnetic waves to image shallow subsurface geological structures where a high power pulse
generator and transmitting antennae generate a wide-band electromagnetic signal of known center
frequencies that propagate through the subsurface and reflects at interfaces with different dielectric and
conductivity characteristics. Borehole RADAR is an essential electromagnetic tool that can
characterize subsurface fracture like fracture location, orientation and roughness depending on
changing of electrical conductivity and dielectric permittivity of the subsurface fracture property which
represent important factors in geothermal energy extraction and development. Variations of these
electrical properties of fracture can be caused by several factors including changes in fracture structure
(fracture width and upper or lower surface roughness of fracture) itself in addition to the fluid content
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and composition inside the fracture. The analysis of the reflected borehole RADAR signal enables us to
understand several subsurface feature when it correlates with electromagnetic simulation results.
EJISST-ID 144
Evaluation of Crack Elongation Performance of UHP-SHCC as a Surface
Repairing Material
Ahmed Kamal Abd Elzaher and Miroru Kunieda
Nagoya University
Cairo University
eng_ahmed_kamal@hotmail.com
One of the FRCC with novel mechanical properties is Strain Hardening Cementitious Composites
(SHCC) that exhibit multiple fine cracks and strain hardening in tension. The advantage to use SHCC
as a repair material is to obtain distributed fine cracks, which reduce penetration of substance into the
inside of structures. Although the crack width is one of the important factors on durability of concrete
structures, durability of matrix itself should be also controlled. The Authors developed special type of
SHCC having durable matrix, and investigated applicability of the material to repair application. Most
researches on the SHCC including UHP-SHCC have focused on the results obtained from uniaxial
tensile tests. However, it is well known that crack distribution of the repair material (SHCC) is limited
adjacent to the existing crack in a substrate. So the design procedure considering the crack elongation,
which represents resistance against the localized fracture, should be established for appropriate material
selection. Zero-span tensile test has been proposed to evaluate the crack elongation performance of the
repair material on an existing crack. In this research, the performance of repairing material with strain
hardening behavior was assessed through the three tests: uniaxial tensile tests; zero-span tensile tests;
and flexural tests of RC beams repaired by SHCC. Comparison between crack elongation performances
of the three tests was conducted. According to the zero-span tensile tests, the repair material behavior
with an existing crack can be roughly estimated. The deformation capacity of SHCC through the
uniaxial tensile tests cannot be applied to the design of surface repair application directly.
EJISST-ID 169
Modifed linear viscoelastic model for elimination of the tension force in
the linear viscoelastic
Sayed Mahmoud and Hiroshi Nakazato
Hirosaki University
Helawn University
elseedy@hotmail.com
In recent times, earthquake-induced structural pounding has been intensively studied through the use of
different impact force models. The numerical results obtained from the previous studies verified that
the linear viscoelastic model is recommended in sim-ulating the pounding force time histories during
impact and also nominated this model for simulating pounding at high peak ground acceleration levels,
as long as there is no tensile force involved. The aim of this paper is to overcome this disadvantage by
introducing an improved version of the linear viscoelastic model through a redefinition of the contact
force of the model into two stages of contact, i.e. the approach period and the separation period. This
would require the reassessment of the relation between the impact damping ratio and the coefficient of
restitution. The results for two different impact experiments as well as for shaking table experiments on
pounding between two steel towers excited by harmonic waves are used in this study. In addition, a suit
of thirty ground motion records from thirteen different earthquakes is applied to simulate pounding
between two single degree of freedom systems of different period ratios. The final outcome of this
study demonstrates that the results obtained through the modified linear viscoelastic model are
comparably similar to those found by using the linear viscoelastic model minus the tension force.
EJISST2008 June 8~10
139
EJISST-ID 197
SEISMIC ANALYSIS OF CABLE-STAYED BRIDGE STEEL TOWERS
Mohamed OMAR and Toshiro HAYASHIKAWA
Hokkaido University
South Valley University
moh_omar77@yahoo.com
The damages occurred during the 1995 Hyogoken Nanbu earthquake led to an increased awareness
concerning the response of highway bridges subjected to earthquake ground motions and emphasized
the need for research to provide new procedures and specifications. As a result, the necessity has arisen
to develop more efficient analysis procedures that can lead to a comprehensive understanding and a
realistic prediction of the seismic response and dynamic characteristics of bridge structural systems to
improve the seismic performance. A three-dimensional finite element model is established for a cablestayed bridge steel tower. A fiber flexural element is developed for tower characterization incorporates.
Analytical study on dynamic characteristics of steel tower is performed to investigate the individual
influence of different design aspects. Shape memory alloy material concepts, to improve the bridges
seismic performance, are suggested by providing base plate anchor bolts at the tower base. The
calculated results prove the effectiveness of using shape memory alloy anchor bolts in reducing
structural elements forces and control tower displacement for seismic design. A nonlinear dynamic
analysis including soil structure interaction is developed to assess the effects of soil-structure
interaction on the seismic response and dynamic performance of the cable-stayed bridge steel towers.
Numerical results indicate that considering soil foundation interaction and soil nonlinearities can
reduce force response of the tower model.
EJISST-ID 203
Shear Cracking Behavior in Reinforced Concrete Members
Hassan M. Zakaria, Ueda Tamon
Hokkaido University
South Valley University
eng_zakaria@yahoo.com
To control crack width at the member surface designers may use the guidelines prescribed in building
design codes. These guidelines concerning crack width are meant for flexural crack width, which were
experimentally obtained and cannot be applied directly to prediction of shear crack width, which is
caused by different mechanism. This research tries to throw the light on shear cracking behavior and its
mechanism in reinforced concrete beams. As a collaborative research between Hokkaido University
(Japan), and Dalian University of Technology (P. R. China), an experimental program was carried out
to investigate the influence of the various parameters on shear crack mechanism in reinforced concrete
beams. All the beams were designed to fail as shear failure under static loading. Shear crack
investigation was conducted using digital mechanical strain gauge with a precision of 0.001 mm, to
measure concrete deformations in shear cracking zone, as well as strain gauges were mounted on the
stirrups to clarify the relation between shear crack components and stirrup strain at the intersection with
diagonal cracks. The experimental results reveal that side cover of concrete, stirrup spacing and/or
stirrup configuration shows a significant effect on controlling shear crack width. Finally, the
experimental results show clearly the effects of the studied parameters, which are useful information
for the development of rational shear crack prediction method.
EJISST2008 June 8~10
140
EJISST-ID 207
Using Ground Penetrating Radar for Environmental and Archaeological
Investigation in Egypt
Mahmoud Gaballah and Motoyuki Sato
Tohoku University, Japan
National Research Institute of Astronomy and Geophysics (NRIAG) , Egypt
mahmoud_gabala@yahoo.com
Ground Penetrating Radar (GPR) is a high resolution remote sensing technique where electromagnetic
waves are sent to the ground from a transmitting antenna and the reflected waves are received at the
surface to show the sub-surface features. It is designed primarily to investigate the shallow subsurface
features of the earth, like building materials, archaeological foundation, roads and bridges, and finally
landmine detection. GPR technique has been used successfully in archaeology for over than 30 years in
different applications and with varying results. A brief introduction to the use of the GPR technology in
archaeological survey for the Sphinxes Avenue at Luxor area, Egypt will be presented in this paper.
The research objective of this study was detection of the targets of potential archaeological interest in
two areas located in the pathway of the Sphinxes Avenue using GPR system (RAMAC) equipped with
100 MHz unshielded antennae offered by Sato Laboratory (Center for Northeast Asian Studies
(CNEAS), Tohoku university, Japan). Moreover, a part of this study was done as a scientific
cooperation between Sato Laboratory and National Research Institute of Astronomy and Geophysics
(NRIAG), Egypt. It is difficult to identify the target anomalies immediately from the GPR raw data
profiles because it is usually contain what we call “Noise” or “Interference”. In order to clean up the
noise of the raw data we must be processed the data before interpretation. GPR was able to recognize
anomalous reflected signals, such radar anomalies are believed to be originated from buried
archaeological structures, which might be the buried Sphinx Avenue. From the extracted GPR
instantaneous parameters (instantaneous phase and instantaneous frequency) we can reveal more
subsurface archaeological features and environmental information. The time-frequency analysis using
instantaneous parameters could serve as a helpful approach for extracting more information from GPR
data.
EJISST-ID 212
Recoverability of Existing Bridge Columns under Moderate to Strong
Earthquake
Mohamed Fathy Mohamed Fahmy and Zhishen Wu
Ibaraki University
Assiut University
mfmf1976@yahoo.com
A destructive damage leading to the loss of human life shall be prevented against a strong earthquake
that has a rare probability of occurrence within the lifetime of a structure. In addition, from social and
economic points of view, deterioration in functions of the structure should be avoided as much as
possible, and livelihood and productive activities of inhabitants after the earthquake should be restored
smoothly. Accordingly, the important infrastructures are required to have not only the high strength and
ductility but also the usability and repairability after earthquakes. For bridges, the codes recognize that
it is uneconomical to design a bridge to resist a large earthquake elastically, and therefore some degree
of damage is permitted and expected. The novel concept of this paper is an examination of the
capability for quick recovery of the original functions of retrofitted existing reinforced concrete (RC)
bridges using fiber-reinforced plastic (FRP) jacketing after a moderate or strong earthquake attack.
Based on this concept, the FRP retrofitted columns should have a clear stiffness after achieving the
ideal flexural capacity. This paper presents an up-to-date literature search pertaining to the performance
EJISST2008 June 8~10
141
of retrofitted columns with FRP. The inelastic performance of the retrofitted columns with different
deficiencies is scoped out from the literature review. From the envelope curve of the hysteretic
response of retrofitted columns, thirty nine columns exhibited that the idealized lateral loaddisplacement relation with stable post-yield stiffness, namely, a second stiffness. An empirical model
has been proposed to evaluate the second stiffness of the FRP wrapped bridge columns.
EJISST-ID 262
Hydrous peridotite with Ti-rich chromian spinel "a low-temperature
peridotite overlying slab"
Mohamed Zaki Khedr and Shoji Arai
Kanazawa University, Japan
Kafr El-Sheikh University, Egypt
Khedrzm@yahoo.com
There are a lot of ultramafic rocks of various dimensions throughout the principal metamorphic and
structural belts in Japan. The Happo-One ultramafic mass is situated in the north-eastern part of the
Hida marginal tectonic zone, central Japan, and is considered as a serpentinite mélange. These
ultramafic rocks, being massive or foliated, are mainly composed of lherzolite, harzburgite and dunite.
They have been subjected to regional metamorphism, superimposed by a contact metamorphism by
Cretaceous granitic intrusions. Most of the primary minerals are metamorphosed; relics of primary
olivines have forsterite (Fo) content from 88 to 92 mol%, and relic chromian spinels in dunite show
high Cr-number, 0.73. Primary clinopyroxenes are converted to tremolites or metamorphic diopsides.
Primary orthopyroxenes rarely survive the metamorphism. We found a peculiar mineral assemblage,
olivine + orthopyroxene + tremolite + chromian spinel, in metamorphosed lherzolites. Olivines are
Fo88. - Fo90, and orthopyroxenes with Mg-number, 0.91 on average, show low Al2O3 (0.12 wt%), Cr2O3
(0.11 wt%) and CaO (0.12 wt%) contents. Chromian spinels, which are euhedral and enclosed mainly
in orthopyroxenes, have high TiO2, 3.0 wt% (up to 5.7 wt%) on average and high Cr-number, 0.95 on
average. Bulk chemistry shows that the lherzolites that include this peculiar spinel are low in TiO 2
(0.01-0.02 wt%), and the high TiO2 of spinel comes from the decomposition of both primary TiO2bearing orthopyroxene and /or clinopyroxene during the high-pressure, low-temperature metamorphism
in subra-subduction zone under hydrous conditions. The hydrous peridotite of this mineral assemblage
may represent a transitional stage between a typical primary mantle peridotite and metamorphosed
peridotites (olivine + antigorite + tremolite/diopside + chlorite + magnetite + ferritchromite).
EJISST-ID 275
STUDY OF THE BEHAVIOR OF PILE GROUPS UNDER LATERAL
LOADING
Mahmoud Nasser Hussien and Susumu Iai
Kyoto University, Japan
Assiut University, Egypt
mahmoudnasser2002@yahoo.com
Recently, pile foundation has become the preferred foundation system for high-rise buildings in urban
areas. The behavior of this foundation under vertical static load is well understood. However, less
attention is paid for studying the behavior of pile foundation under the application of lateral loading.
Lateral loads, however, are just as important as vertical loads in designing pile foundations and are
often more complicated. Lateral loads are often developed from wind and earth pressures. More
powerful lateral loads occur as a result of unexpected events such as earthquakes, slope failure, and
lateral spread induced by liquefaction. Loads imposed on pile foundations during earthquakes have
been a major cause of past damage which poses great challenge to the design engineer. The main
purpose of this study is to develop a finite element model that can accurately model the actual behavior
of pile foundation under both vertical and lateral loads accounting for the nonlinearity of material,
EJISST2008 June 8~10
142
nonlinearity of geometry and nonlinearity of status between the soils and the structure, and using the
developed FE model in parametric study to gain insight into the nonlinear response of pile groups to
earthquake loads.
EJISST-ID 286
CRACK DETECTION in CONCRETE STRUCTURES – THEIR
STRENGTHENING USING CFRP
A.M. ANWAR, Kunio HATTORI and Hidehiko OGATA
Tottori University, Japan
National Water Research Center, Egypt
ahmedanwar2000@hotmail.com
In the framework of evaluation and strengthening of hydraulic concrete structures, Ultrasonic pulse
velocity (UPV) test, for evaluation, as well as Carbon fiber reinforced polymers (CFRP), for
strengthening, are commonly used. UPV is considered as a non destructive test that gives fast
indication about concrete quality in situ. In the current work, new approach for determining the
positions and size of cracks in concrete members using UPV test was introduced. Plain concrete
specimens, containing artificial cracks of different dimensions were prepared. The results showed that
crack depths were identified with better accuracy compared to other conventional methods. On the
other hand, CFRP have proven adequacy in rehabilitation of variety of structures on both practical and
experimental fields. However, their performance with arched structures is still under consideration. The
current research also addresses the use of CFRP in strengthening, of prototype models of arched
hydraulic structures typically used in regulator vents in Egypt. Arched plain concrete specimens
strengthened with CFRP sheets applied at soffit, sides, and with combination of both together were
destructively examined. Results showed that soffit strengthening was good in achieving higher section
capacity while sides strengthening were good in enhancing the ductility. Combination between both
soffit and sides strengthening showed effectiveness in achieving higher section capacity with
reasonable ductility.
EJISST-ID 053
Inverse CFD Modeling as a Tool to Identify Pollution Source Locations in
Outdoor Environments: Application of Reversed Time Marching Method
Mahmoud Bady, Shinsuke Kato and Hong Huang
University of Tokyo
Assiut University
mbady@iis.u-tokyo.ac.jp
The present research introduces a technique to determine pollution source locations in urban
environment -when the contaminant concentration field is known- through the use of reversed time
marching method (RTMM). The method depends primarily on the solution of the transport equation of
the contaminant with time integration in the negative direction. This leads to reversing the velocity
field and also the diffusion term. The study demonstrates how to use the inverse CFD model with the
reversed time marching method to identify pollution sources in urban environments. In order to
examine the accuracy of RTMM in identifying pollution sources in urban areas, two examples were
given. In the first one, a simple boundary layer flow was considered and a pollutant source was emitted
for variable wind conditions. In the second example, the wind flow around a single building was
investigated for two different source locations. In all cases, steady state numerical simulations were
carried out at first in order to estimate the wind flow fields. With the steady-state airflow patterns,
direct CFD modeling (forward-time simulation) was used to calculate pollutant concentration
distributions for step-function sources. In the last stage, the transport equation of the contaminant was
solved again but with the reversed flow field and the negative diffusion term. By using peak
contaminant concentration, one could identify the contaminant source. Results of the study
EJISST2008 June 8~10
143
demonstrated that the RTMM is robust enough to identify pollution sources locations in urban areas.
However, the source prediction accuracy decreases in cases of weak convection.
EJISST-ID 057
Numerical Predictions of Pollutant Dispersion near Buildings: Effect of
Cell Geometry
Mohamed M. Hefny and Ooka Ryozo
The University of Tokyo
South Valley University
hefny@iis.u-tokyo.ac.jp
Since the advent of the industrial revolution, mankind activities have created many pollutants that have
disturbed the ecological balance of our planet. Within these contexts, reliable predictions of the
dispersion of fluids that could represent chemical or pollutant substances within our environment is
very important. Computer based simulations offer fast, economic solutions rather than experimental
simulations. Computational Fluid Dynamics (CFD) can aid in understanding the complex flows of
environmental interests such as the pollutant/chemical dispersion in the urban cityscapes. The objective
of this research is to find out the influence of the cell geometry on the CFD results of the pollutant
dispersion around buildings. More precisely, the effect of two cell types is investigated, namely, the
hexahedral cells and the tetrahedral cells. The truncation errors are compared between the two mesh
styles and it is proved that the tetrahedral-based mesh gives higher truncation error compared to the
hexahedral-based mesh. Moreover, the effect of mesh non-orthogonality is investigated and it is found
that it gives higher truncation errors. The flow problem of pollutant dispersion around buildings is
solved on both mesh systems for similar density to give useful insight into the accuracy of the two
mesh systems considered.
EJISST-ID 034
Regional Environment Simulator: Atmosphere, land surface Ocean
Interactions
Mohammed Elsayed Abou-Elhaggag and Takao Yamashita
Hiroshima University
Cairo University
Haggag-moh@hiroshima-u.ac.jp
A multi-layer land surface model (SOLVEG) is dynamically coupled to the non-hydrostatic
atmospheric model (MM5) to represent better spatial variations and changes in land surface
characteristics compared with the land surface parameterization schemes included in the MM5. This
coupled model is applied to the heavy rain events occurred in Kyushu Island, Japan, from July 20 to
July 25 in 2006. The test computations are conducted by using both the developed coupled model and
the original land surface parameterization of MM5. The result of these computations shows that
SOLVEG reproduce higher ground temperature than land surface parameterization schemes in the
MM5. This result indicates the feedback of land surface processes between MM5 and SOLVEG plays
an important role in the computation. The most pronounced difference is in the rainfall simulation that
shows the importance of coupling SOLVEG and MM5. The coupled model accurately reproduced the
heavy rainfall events observed in Kyushu Island compared to the original MM5 from both the spatial
and temporal point of view. These results shows that realistic simulation of rainfall event strongly
depends on land-surface processes interacting with cloud development that depends on surface heat and
moisture fluxes, which in turn are mainly determined by land surface vegetation and soil moisture
storage. Soil temperature/moisture changes significantly affect the localized precipitation and modest
improvement in the land surface representation can enhance the heavy rain simulation. MM5-SOLVEG
coupling shows a clear image of land surface-atmosphere interactions and the dynamic feedback on
convection initiation, storm propagation and precipitation.
EJISST2008 June 8~10
144
SESSION 16: Civil and Environmental Engineering –
Air Pollution
EJISST-ID 246
Analysis on Urban Expansion Issues of Developing Cities in Egypt
Amany N. HAREEDY and Atsushi DEGUCHI
Kyushu University, Japan
El-Minya University, Egypt
amany_nagi@yahoo.com, atsushi@arch.kyushu-u.ac.jp
It’s widely observed that many of the world cities suffer from the randomly creeping of the urban
growth and other mixed and discordant uses to their outer edges. Egypt, as a developing country, faces
this growing phenomenon. The Egyptian cities expanded over time and different changes have
occurred in their historical formation and urban characteristics. That’s followed by many problems that
took place either in absence or misapplication of scientific urban planning and preserving restriction
laws. From analyzing the cities’ expansion patterns, it’s found that urban degradation of their urban
form became a serious problem due to the continuous informal expansions. Moreover, these expansions
represent a real economic threat that swallowed about 80% of the agricultural lands mostly located on
cities’ peripheries. And despite of excessive studies and governmental attempts, the informal expansion
problem became the main character of the Egyptian cities that still continuing out of control and which
need great efforts for a sustainable solution. Therefore, the study here figured out a thorough vision of
the problem of the Egyptian cities’ urban expansion, describing the country, the urbanization
magnitude, and analyzing the urban expansion patterns of its developing cities. Finally, it included: the
typology of each urban expansion pattern, the regulating laws for the urban planning and building
construction works, the government policies and their deficiency in solving the informal expansion
problem.
EJISST-ID 247
Distributed Water Balance Model in Watershed Coupled With River Flow
Routings
Hassan S. Hemaid and N. Tanaka
Saitama University
South Valley University
hshemaid@yahoo.com
Accurate methods for predicting rivers' flood capacity and water level during flooding are essential to
protect and development the floodplains and surrounding area. Most of natural rivers and channels
consist of deep main channels and one/two relatively rough and shallow floodplains which are used as
a water runway or storage area at the peak flood time. For natural rivers, the needs to use dynamic
models are increased to get accurate estimation of flow discharge and water surface elevation. The
floodplain's roughness and the momentum exchange between it and the main channels affect the
calculated discharge hydrograph and rivers' water surface profiles especially after water run into the
floodplains. This research focuses on the application of both dynamic and diffusive hydrological and
river flow modeling techniques in flat and steep area to predict flood discharge and water depth in
natural rivers and to verify the effect of the floodplain's roughness on the calculated discharge and
water depth. Using the current model, the discharge and water level at any location of the stream
system could be estimated. The diffusive models are suitable in the hill areas and rivers with steep
slopes where dynamic models are suitable for natural rivers with floodplains and mild slops, for river
flow with high water depths and for flat areas.
EJISST2008 June 8~10
145
EJISST-ID 181
Preparation of Carbon Coated W18O49 with Iron and Its Photoactivity
under Visible Light
Hany H. Abdel Ghafar, Tomoki Tsumura and Masahiro Toyoda
Oita University, Japan
National Research Center, Egypt
hany_ghafar@yahoo.com
Preparation of carbon coated W18O49 with and without iron was carried out through solid state reaction
of WO2.9 and PVA (polyvinyl alcohol) as carbon precursor with iron acetate at 800 oC in N2. W18O49
was recognized on XRD patterns through in this process. Obtained carbon coated W18O49 revealed
absorbance in the whole of wavelength. The carbon thin layer formed on the surface of W 18O49 particle
worked as adsorbent. Increasing of addition of iron acetate derived the decreasing of W 18O49 phase
with deposition of FeWO4 phase. Phenol was selected as a decomposition material. Decomposition of
phenol by using carbon coated W18O49 with iron was carried out under visible light irradiation.
Addition of 1% iron acetate and 10% PVA exhibited highest photoactivity in its aqueous solution.
Carbon coated W18O49 with iron exhibited higher photoactivity than it without iron. Carbon coated
W18O49 with iron can be used for the decomposition of organic pollutants in water under visible light.
EJISST-ID 211
Observation of Coastal Morphology Using X-band Radar
Elsayed M. Galal and Satoshi Takewaka
University of Tsukuba, Japan
Suez Canal University, Egypt
sayed@surface.kz.tsukuba.ac.jp
Intertidal morphology was monitored continuously with an X-band radar at research pier HORS
located in Hasaki, Japan facing Pacific Ocean. Hourly averaged radar images were processed to
observe longshore distributions of shoreline and bar positions. X-band marine radar is an imaging radar
that is capable of tracking the movements of wave crests over an area spanning several kilometers, and
is becoming popular in coastal studies these days. The most attractive feature of using an X-band radar
system is its ability to collect data on coastal processes, continuously and remotely, in bad weather
through moderate levels of fog and rain that typically accompany erosive high-wave conditions. This
paper shows some applications of radar image data in observation the coastal morphology. By
digitizing the shoreline and bar positions from hourly averaged radar images observed in the years
2005 and 2006, the results show that the variations of longshore mean shoreline positions and their
fluctuation intensities showed a seasonal change which followed the so-called beach-cycle. Wavy
features with wavelength of several hundred meters were observed in shoreline and bar locations at low
energy periods. Longshore pixel intensities close to shoreline and bar were extracted from timeaveraged radar images for every hour to process longshore time-stack image. Longshore migration
speeds of shoreline and bar wavy features were estimated by cross correlation analysis of the timestack image. Migration speeds were compared to measured longshore current speeds at the pier and the
longshore component of the wave power, showing that they are highly synchronized for most
conditions.
EJISST2008 June 8~10
146
EJISST-ID 279
Homogenization theory application as up-scaling technique for the
hydrological parameters in the arid and semiarid areas, Wadi Assiut as
case study
M. Saber, T. Hamaguchi and T. Kojiri
Kyoto University, Japan
Assiut University, Egypt
saber@wrcs.dpri.kyoto-u.ac.jp
Understanding of hydrological processes in the arid and semi-arid regions are so important due to the
importance of the water resources in such areas where the water is the main dominant resource for
domestic, manufacturing and irrigation use. Also there are many severe problems in such regions which
represent in the scarcity of data and the lack of high quality observations and consequently the
difficulty of developing the powerful hydrological models. Due to the prescribed problems, we
introduce our research as preliminary step to solve such problems. So, our research proposes to apply a
homogenization method of up-scaling hydrological parameters related to a distributed runoff model
from microscopic aspects up to macroscopic ones in the arid and semi arid areas. These parameters are
equivalently derived from the mathematically formulated descriptions based on the conservation of
surface and subsurface water quantities. A surface flow direction through a flow direction/routing map
is significant to calculate the homogenized values of up-scaling hydrological parameters. It will be
proven that equivalently homogenized parameters stem just from the macroscopic-modeled parameters
and the numbers of longitudinal and its transverse cells, and that a conventional way of equivalent
parameters by weighted arithmetic mean is simple and easy but inadequate to figure out. It is concluded
that our approach of using upscaling technique of the homogenization theory is a good preliminary step
to apply the down-scaling technique to overcome the problem of scarcity of the data in the arid and
semi arid areas.
EJISST-ID 192
Laboratory tests on the occurrence of fluoride rich groundwater of Tono
area, Japan
Abdelrahman M. Abdelgawad and Kunio Watanabe
Saitama University, Japan
Assiut Institute of Survey and Irrigation, Egypt
Abdo_gawad2003@yahoo.com
The occurrence of high fluoride ion concentrations in the groundwater of Mizunami area, Japan has
been experimentally studied. In this study, the origin of fluoride-rich groundwater was mainly
examined by several methods. Our methods based on the water-rock interaction test using granite
specimens sampled from a boring core drilled at the site. Microscopic observation of granitic
specimens was performed to further identify the major rock forming minerals and the effects of
hydrothermal alteration on rock matrix texture. Thermodynamic considerations of the solution
chemistry were performed; in order to estimate the saturation indices for each mineral. Then, the results
were compared with field data observed in and around the site. Experimental results show deviation in
fluoride concentrations with time leached from different granitic specimens. It may be due to the spatial
distribution of fluoride rich mineral in granite mass. The varying in the granitic rock conditions is
one of the main clue for changing the fluoride ion concentration. Weathering and alteration processes
affect rocks by changing their physical, chemical, mineralogical and rock mass properties. The increase
of the reaction time led to enhance leaching of the fluoride ion from granite. Comparison between
experimental results and field data shows the fluoride concentration decreases in the deep underground
due to the existence of high saline water. These observations imply that the fluoride concentration is
not only a function of travel time but also influenced by coexisting ions in groundwater.
EJISST2008 June 8~10
147
EJISST-ID 036
Stiffness Degradation Process during Liquefaction Applied to the Port
Island Site during the 1995 Hyogo-ken Nambu (Kobe) Erathquake
Mostafa Thabet Mohammed and Koichi Nakagawa
Osaka City University
Assiut University
mostafa@sci.osaka-cu.ac.jp
The nonlinear response of soil due to large strain is examined through simulations of events before,
during, and after the 1995 Hyogo-ken Nambu (Kobe) Earthquake using downhole array data recorded
at Port Island, Japan. Linear site response analyses were carried out using finite element method for the
records of foreshock and aftershock to evaluate shear wave velocity structure variations. Shear wave
velocities were estimated based on S-wave travel time delays and heuristic search within limited search
space of shear wave velocity values. Linear simulations of foreshock and aftershock reveal that the
shear wave velocity is strongly suppressed during aftershock at depth of 5 - 27 m. Nonlinear
simulations were carried out for the horizontal components of the mainshock, after which weighting
functions were multiplied by the nonlinear simulated ground motions. These weighting functions were
applied to remove the misfit time window of the nonlinear simulated ground motions when compared
to the observed records. Finally, stacking was applied for the weighted nonlinear simulated ground
motions. The final nonlinear simulated ground motions indicate a degradation process of stiffness with
time and a clear dependence of liquefaction-induced nonlinearity the direction of particle motion.
EJISST-ID 304
“The habitus-Field networking model” an alternative subcontracting
arrangement in Japan: Evidence from subcontracting clusters in
Higashiosaka district
Tarek Mohamed Ali
KOBE University
SOHAG University
Tarek2110@yahoo.com
Subcontracting has often been pointed to as a distinctive aspect of Japanese business networks by
which Japan has a unique reputation for its industrial success achieved around the world.
Subcontracting arrangements have been regarded as important source of efficiency that secured
survival of Japanese economy during several business cycles. Japanese subcontracting arrangements,
therefore, have been a major research topic in the business network literature that attracts significant
attention from both Japanese and western scholars. After decades of research, these business networks
are still poorly understood in terms of the dynamic mechanism that helps sustaining processes of
innovation. Major research topics in this field emphasize linking subcontracting arrangements with
other factors such as productivity, profits and managerial and technological sophistication. However,
providing an applicable networking model that enables Japanese small subcontractors to cope with
recent change in their business environment has not yet been conducted exclusively. From this line of
reasoning, this paper proposes a model for the recent subcontracting arrangement in Japan. This is
through analyzing the up-to-date transformations of Japanese subcontracting system in the course of
the changing intensities of Japanese small and medium subcontractors. To portray the intended model,
we adopt the notion of “habitus-field” introduced by Pierre Bourdieu in 1995. The model uses small
and medium subcontracting manufacturers as the central concept to define their relations with the
prime contractors. Such a mutual inter-firm relationship reveals the dynamic mechanism by which both
parties can benefit from each other’s attributes and obtain the best of both worlds.
EJISST2008 June 8~10
148
SESSION 17: Mechanical Engineering
EJISST-ID 193
Laser Welding of High strength Steel
Khalid M. Hafez and Seiji Katayama
Osaka University, JAPAN
Central Metallurgical R&D Institute, EGYPT
khalidhafez@yahoo.com
The fusion welding processes have historically been, and are today, commonly used in the manufacture
of automotive structures. Recent increased usage of High Strength Steels (HSS) in automotive designs
posed a desire to evaluate the application of fusion welding processes relative to the joining of HSS.
The weldability in laser welding of carbon steels is different from that in arc welding due to the rapid
heating and cooling characteristics. The typical HSS sheet can be laser welded with little loss of
performance. However, the high solidification and cooling rates of laser welding may affect the
microstructural integrity and resultant formability of high-strength steel joints. High speed laser
welding offers extremes in solidification and cooling rates approaching those of resistance spot welds.
However, the metallurgical behavior of laser welds on these materials has not been well characterized
and is not well understood. Experimental investigations were carried out to examine the influence of
welding condition, shielding gas, and travel speed of both MIG and Laser welding weld dimension,
microstructure and hardness during overlap laser bead on plate welding. The results show that Laser
welding produced narrow welds with increased hardness. It was found that even with full penetration
welds there can be significant variation in the microstructure and hardness of weld within a weld line
due to the very rapid solidification.
EJISST-ID 235
Numerical Simulation of a Hydrogen Leakage Jet
M. F. El-Amin and H. Kanayama
Kyushu University, Japan
South Valley University, Egypt
mfam2000@yahoo.com
Hydrogen is expected as new fuel instead of fossil fuel. It will be used as fuel of a fuel cell for which
development is performed actively. But it is difficult to experiment the hydrogen dispersion in case of
hydrogen leaks. Therefore clarifying the hydrogen dispersion with numerical analysis becomes
important. Furthermore, hydrogen dispersion under various conditions can be clarified with numerical
analysis, which is useful to use hydrogen safely. This paper deals with computer simulation of the
hydrogen dispersion by a finite element method. The mathematical model of hydrogen dispersion is
governed by the momentum equations, the continuity equation, the energy equation and the hydrogen
mass conservation equation. The model presented here is an Axisymmetric Ceiling Model.
EJISST2008 June 8~10
149
EJISST-ID 205
Modeling of fatigue performance of structures strengthened with
externally bonded CFRP composites
Hesham M. Diab and Zhishen Wu
Ibaraki University
Assiut University
heshamdiab2@yahoo.com
Fundamental understanding of the bonding behavior of fiber reinforced polymer (FRP) laminates is of
prime importance for the development of design guidelines and codes for concrete structures
strengthened with externally bonded FRP reinforcement as a bond critical application. Therefore, a
design strategy to evaluate the fatigue bonding and debonding propagation along FRP-concrete
interface needs to be adopted. This paper concerns the development of a nonlinear hybrid model for
studying the FRP-concrete interface behavior under fatigue loading. In this model, a system with
viscoelastic elements that describes the increment in elastic and creep-fatigue slip is placed in series
with an element that schematizes the softening behavior. Based on the creep-fatigue interaction, the
proposed model describes the behavior of FRP-concrete interface before debonding initiation.
Afterward, the fatigue debond growth is governed by the softening model that depends on the strain
fracture energy of the FRP-concrete interface and a damage accumulation factor. A series of double lap
shear specimens subjected to variable maximum fatigue loading has been carried out to calibrate and
validate the proposed model. Using the subroutine mechanism offered by finite element Diana code,
the results show the ability of this model not only to predict the fatigue life of double-lap shear
specimens but also to provide a useful insight into FRP-concrete interface failure mechanism due to
fatigue loading. Moreover, this model can be appropriately capture the fatigue slip deformation and
FRP strain distributions due to fatigue loading. Having this model gives the opportunity to numerically
study the fatigue performance of structures externally strengthened with FRP sheets.
EJISST-ID 120
Control of Flexible Manipulators Using Visual Data
Tamer Mohamed Mansour and Masaru Uchiyama
Tohoku University
Assuit University
Tmansour1@yahoo.com
The topic of the research is the control of flexible manipulators. Nowadays, flexible-link manipulators
are especially feasible for applications in space, such as in orbit or on other planets because the cost for
launching is proportional to the weight of the object to be launched. Not only the benefits of the lower
energy consumption compared with rigid link robots but also those robots can work in a faster speed
than the normal massive rigid robots. A safer operation can be granted due to reduced inertia in medical
applications. The suppressing of vibration of the end effector is considered as one of the great
challenges facing the spreading of using flexible manipulators in wide applications. This part of
research presents a Modified Proportional-Integral- Derivative (MPID) controller used to suppress
vibration of flexible manipulator moving vertically. To attain the vibration suppression a vibration
variable should play role in the control signal, which drives the flexible manipulator. The proposed
controller is based on the conventional PID control but the integral term is replaced with another one,
which mainly depends on the vibration of the end effector. Camera becomes an inherent part of space
manipulator, using the MPID controller with the visual information recorded by the camera makes the
strain measuring circuits and amplifiers unnecessary. This means reducing the hardware used in the
control of flexible manipulator. The novelty of the results lies in the fact that the measurement of the
rate of change in deflection, which is used as a vibration variable, has been done without the need of
numerical differentiation. Experiments successfully demonstrate that using the visual data with an
EJISST2008 June 8~10
150
observer based on Kalman filer can achieve a noticeable damping of the end effector vibration of the
flexible manipulator.
EJISST-ID 128
Design and Simulation of a Tactile Sensor for Soft-Tissue
Ahmed. M. R. Fath El-Bab, Mohamed. E. H. Eltaib, Mohamed. M. Sallam and Osamu Tabata
Kyoto University
Assiut University
Ahmed_rashad@yahoo.com
Today, much attention is given to tactile sensing in medical applications such as minimally invasive
surgery. Artificial tactile sensing is a mean for objective measurement of the tissue properties. It could
be used for detection of cancerous lumps or for deciding how much the healthiness of a tissue. A
detailed design procedure for a tactile sensor for compliance detection is developed. The sensor
principle is based on the concept of applying two springs, with considerably different stiffnesses, to
soft tissue for compliance detection. The spring stiffnesses are chosen to be associated with the soft
tissue properties. The sensor design parameters are optimized to give high sensitivity and linearity of
the sensor output with taking into account the effect of crosstalk between two springs due to the tissue
deformation. A 250 μm mesa size is used as example to apply the design procedure. The proposed
design procedure shows for 250 μm mesa size, the best sensor's springs values are 110 and 4500 N/m.
Then, a finite element model is developed to investigate the sensor performance with the designed
parameters using two types of spring end, namely cubic and spherical in shape. The results show a
significant stability of reading with the cubic end rather than the spherical one during pushing the
sensor against a tissue. Finally, the same finite element model is used with changing the distance
between the spring ends to show the crosstalk effect due to the tissue deformation. Based on the above
design procedure, a micro-machined tactile sensor with a cubic spring ends will be fabricated in the
next step.
EJISST-ID 201
Circular Path Estimation of a Rotating Four-Legged Robot Using
a Hybrid Genetic Algorithm LSM
Abeer Mahmoud and Tokuji OKADA
Niigata University, Japan
Ain Shams University, Egypt
abeer_f13@yahoo.com, okada@eng.niigata-u.ac.jp
Robot locomotion can be roughly classified into two ways in its driving; wheeled locomotion and
legged locomotion. Research activities concerning the first are seen in the design of active suspension,
whereas control aspects are important subject for the second. Evidently, advantage of the wheeled
locomotion is in performances in power consumption and velocity. Legged locomotion is effective in
variety of ground conditions, but not useful with high speed. There exists now an interest for a new
type of vehicle which inherits both advantages of wheeled and legged locomotion. Control of such
robots is not a trivial problem since we must find algorithms and strategies for utilizing two ways and
exhibiting complex interactions with environment. We aim to develop a mobile robot control algorithm
for a wheeled- legged robot so that it can track a given path with a small error. As the research going
on, we discuss a C++ object oriented based simulator for the wheeled-legged robot called PEOPLER
which can behave as a four wheeled or four legged robot on demand. This simulator facilitates the
analysis of the robot circular trajectory on a flat terrain considering ground friction coefficient and
payload operating on each of landing contacts. Also, we propose a new hybrid method called GALSM
for estimating circular radius of locomotion route. This hybrid estimation model is designed by
combining the well known least square method (LSM) and genetic algorithm (GA). The results showed
that the hybrid model is promising in steering the robot on the ground in real.
EJISST2008 June 8~10
151
EJISST-ID 224
Influence of Micro-Bubbles on the Heat Transfer and Pressure Drop of
Water Flows in A Helical Pipe
Mohammed M. Shatat and Shinichiro Yanase
Okayama University, Japan
Suez Canal University, Egypt
morsynhomar@yahoo.com
Fluid flow in pipes occurs in many domestic and industrial systems. Flow can be driven by pumps
providing a pressure head that overcomes the wall friction or the drag in the flow. Thus, for a given
flow rate, a decrease in drag force, resulting in a decrease in pressure head, is a desired operating
strategy. Drag reduction is commonly achieved by adding chemicals such as surfactants or polymers to
the liquid. Through the formation of surfactant micelles or polymer chains in the bulk liquid, the
frequency of formation and size of the turbulence eddies can be dampened. This results in the boundary
layer in the pipe wall becoming less turbulent, resulting in less drag in the liquid flow. While the use of
chemicals is effective in reducing drag, the chemicals can be costly and environmentally unfriendly.
One of the methods to reduce the skin friction drag is gas injection into a liquid boundary layer, such
injection results in the formation of microbubbles that produces drag reduction. During the past
decades, many research efforts have been devoted to microbubble drag reduction. But, unfortunately,
most of the attention concerned the flow over flat plates and few researchers were interested in the flow
in pipes, also, there’s a lack of information about the effect on heat transfer characteristics. In pipe flow
very little information is known about the mechanism of the microbubble drag reduction phenomenon
and microbubble-wall interactions. The purpose of the present work is to investigate the effect of the
production of microbubbles in water on the pressure drop and heat transfer characteristics when flows
in straight and helical pipes, by measuring the effect of the void fraction, inlet temperature, Reynolds
number, and geometry of the pipes, on the average friction coefficient , and the local and average heat
transfer coefficient between the pipe wall and the water flow under the condition of constant heat flux.
EJISST-ID 251
Spray Behavior near the Nozzle of a DISI Multi-Hole Injector Using Phase
Doppler Anemometer
Fatma Badry Mohamed Ahmed and Eiji Tomita
Okyama University, Japan
south valley University, Egypt
fatmaowny@yahoo.com
Phase Doppler Anemometry (PDA) is a non-intrusive technique used to simulteously determine the
droplet size and velocity at a specific point in the spray. Focusing the control volume at different
locations within the measurment zone allows the characterisation of both temporal and spatial profile of
spray behaviour. The spray from a multi- hole injector applied to direct injection spark ignition (DISI)
engine was investigated. The spray has been injected into a constant volume chamber and has been
visualized with a high speed video camera with a long distance microscope and quantified in terms of
droplet velocity and diameter with HiDense PDA system. HiDense PDA system permits accurate
measurements in spray with extremely high particle concentrations, and it is the only PDA system
available that provide high quality measurements in the core region of the spray cone. So the spray
close to the nozzle has been investigated. Also the spray at 90 mm far from the nozzle has been
investigated at different injection pressure. PDA data have been processed by using a time-dividing
method which divides the spray information into four distinct periods (F, C, R and T). As a result it
was found that large particles ~ (85 micro m) which are injected at high speed ~ (90 m/s) in the earliest
stage lose their velocity rapidly due to breakup into smaller droplets and are overtaken by smaller but
slower particles which are emitted during a later stage. The results also show that within the measured
range the effect of injection pressure on droplet size was rather small.
EJISST2008 June 8~10
152
EJISST-ID 253
Transient Spray from Port Fuel Injector
Mohamed Fathy Cidek Esmail and Eiji Tomita
Okyama University, Japan
south valley University, Egypt
mfsadik@yahoo.com
Nozzle geometry of port fuel injector is major issues due to the influence on internal flow, cavitation
phenomena, spray characteristics and therefore atomizations behavior, which are very important to
reduce the exhaust unburned hydrocarbon emissions during cold starting. The present paper reports an
experimental investigation of the spray droplet size injected from PFI injector and the effect of internal
structure of PFI on the stability of primary spray behavior was carried out. Several types of PFI were
tested to investigate the effect of cavity type of injector, hole pitch diameter, hole diameter, nozzle
angle and thickness of orifice plate on the spray. The investigation of both spray droplet diameter and
stability of spray structure was performed using an ultra high-speed camera (max. camera speed
1Mfps) with a long-distance microscope (whole image). The visualized experiments were carried out in
a closed chamber at the atmospheric pressure. With back-lighting, the time-series images of the spray
behavior were obtained. Using ultra high-speed camera with long- distance microscope and Barlow
lens, droplet diameter could be visualized with high temporal resolution (magnified image). Surface
waves of primary spray boundary can be recognized. Experimental results of droplet diameter, spray
angle and stability were compared with droplet breakup estimated from WAVE modeling. Straight
cavity type makes larger spray angle than taper cavity type, however, the spray angle is more
influenced by the nozzle geometry rather than the other spray characteristics.
EJISST-ID 301
Punching Shear Strength of Concrete Slab Strengthened with FRP under
Various Environments
Ahmed Sabry Farghaly and UEDA Tamon
Hokkaido University
Assiut University
asabry75@hotmail.com
External bonding of fibre-reinforced polymer (FRP) sheets has emerged as a popular method for the
strengthening of reinforced concrete (RC) structures. In this strengthening method, the performance of
the FRP-to-concrete interface in providing an effective stress transfer is of crucial importance. Indeed,
a number of failure modes in FRP-strengthened RC members are directly caused by debonding of the
FRP from the concrete. The motivation for this work is the fact that, although there is a large amount of
experimental data available on the FRP strengthening of concrete structures, a full understanding of the
various load–deformation behaviors and debonding phenomenon is still lacking specially in the RC
slabs strengthened with FRP sheets. In this paper, results from nonlinear finite element analyses of
fibre reinforced polymer (FRP)-strengthened concrete slabs are presented. A 3D FEM program
developed at Hokkaido University was used to predict the punching failure mechanism and its strength
for slabs strengthened with FRP. The numerical models presented in this paper adopt an interfacial
bond model which found to be applicable to simulate the debonding behavior of the slabs strengthened
with FRP laminates. Results of the different factors are presented and compared with published test
data available on the literature, and a very good agreement in terms of the ultimate load carrying
capacities, load–deflection behavior and modes of failure, are obtained.
EJISST2008 June 8~10
153
EJISST-ID 061
Assuming the Crystallization Age and Thermal events affected the
Basement Complex, Abu Zenima area West-Central Sinai, Egypt
Sherif Mansour and Noriko Hasebe
Kanazawa University
Suez Canal University
sherif@stu.kanazawa-u.ac.jp
Formation age of the basement rocks and detailed data about the thermal events of Abu Zenima area
will provide us information which is of a great importance in the understanding of the geologic and
tectonic history of the area of study in addition to its economic probability. Uranium-Lead, ThoriumLead, and Fission Track dating techniques were used, all of which depend on the accumulation of the
radiation products (Pb) or damage (track) in the radioactive element (U or Th) bearing mineral as a
function of time. Information about the thermal history is obtained from the distribution of track
lengths, because each fission track is actually formed at different time, and tracks became shortened as
a function of maximum temperature it has experienced (Gleadow et al., 1986). Therefore measurement
of tracks lengths and their distribution provide direct and powerful method of differentiating between
contrasting thermal histories. Rocks formation age (crystallization age) which would be in average of
580 Ma is combatable with previous idea of the Arabian-Nubian shield formation in Neoproterozoic,
while the thermal history modeling would produce promising information about thermal anomalies
caused by tectonic events, that give us a clear idea on geologic history of the area of study and its
importance to understand evolution of Sinai peninsula.
EJISST-ID 199
Fabrication of aluminum nitride coatings by plasma spraying
Mohammed Shahien, Motohiro Yamada, Toshiaki Yasui and Masahiro Fukumoto
Toyohashi University of Technology (TUT)
Central Metallurgical Research and Development Institute (CMRDI)
shahien@ajp.pse.tut.ac.jp
Aluminum nitride (AlN) is an attractive material. AlN thermal sprayed coating is expected to
contribute to semiconductor equipment and so on. However, fabrication of AlN coatings by
conventional thermal spray processes such as flame spray and plasma spray was impossible due to
thermal decomposition of AlN powder during spraying. In order to fabricate AlN coatings, reactive
plasma spraying is a promising process. Reactive plasma spraying, in which metal powder reacts with
surrounding active species in the plasma, enables to fabricate non-oxide ceramic coatings without
thermal decomposition during spraying. In the previous studies, it was possible to fabricate AlN based
coatings by reactive plasma spraying using pure Al feedstock. However, most of coatings consisted of
quite brittle agglomerates, which synthesized by nitriding reaction of sprayed Al particles. Therefore, it
is necessary to prevent the formation of the agglomerates. In this study, Al/AlN mixed powder was
used for feedstock powder. AlN particles in the feedstock prevent the formation of agglomerates during
spraying. In this study, mechanical alloying (MA) method is adopted to mix Al and AlN powders. MA
method can fabricate AlN particle dispersed Al powder. The MA powder injected into the reactive
plasma and deposited onto a substrate. It was possible to fabricate thick AlN based coatings without
including the agglomerates. The particle size of feedstock was affected to the thermal conductivity and
amount of AlN phase of the coatings.
EJISST2008 June 8~10
154
EJISST-ID 139
On the discrepancies among seismic wave velocities in soft sediments
obtained using different measuring techniques
Khaled M. Mamoun and Koichi Nakagawa
Osaka City University
Suez Canal University
k_m_mamoun@hotmail.com
Seismic wave velocity data are essential for many geological, geophysical, and geotechnical studies.
The problem is that different seismic wave velocity logging techniques yield various wave velocity
values for the same rock units. These variations in wave velocities may be due different causes. One of
the main causes is the difference in the wave frequency employed by each technique. In this study,
compressional (P) and shear (S) wave velocity data acquired in the Osaka Basin, Japan using two field
methods (suspension and down-hole) and laboratory tests, using the pulse transmission, are compared
to each other to reach a comprehensive understanding of the effect of frequency on the acquired
velocities. Results show that grout casing used for strengthening borehole walls, in some cases, has a
great influence on the P-and S-wave velocity acquired using the suspension method that employs short
wave length, while the down-hole velocities are not affected. At the near surface zone, the P- wave
velocity shows extremely small values, smaller than P-wave velocity in water. This tendency has
become large with down-hole method. This dispersion in the P-wave velocity is explained by the effect
of relatively high gas content in the soil. This explanation is examined by conducting a numerical
analysis based on White’s model (1975). The analysis also shows the dependence of the effect of
partial gas saturation on frequency. A procedure presumes the existence ratio of the gas phase is
presented. It was possible to estimate the gas saturation distribution in several positions. It became
clear that sand soils are more susceptible to adsorb gas than the other soil types.
EJISST2008 June 8~10
APPENDIX 1:
SYMPOSIUM
VENUE
155
EJISST2008 June 8~10
156
Access to WASEDA University
Nishi WASEDA Campus
For 8 June 2008
Okuma Tower,
Building Number 26,
ROOMS: 501, 502, 503, 601, 602, 603, 701, 702, 703
EJISST2008 June 8~10
157
For 9 and 10 June 2008
Center for Scholarly Information
Masaru Ibuka Auditorium
Big Hall (400 persons) First Floor
Third Floor Map
EJISST2008 June 8~10
Hall 1 and 2 (100 persons) - Third Floor
Hall 2 and 3 (100 persons) - Third Floor
158
EJISST2008 June 8~10
APPENDIX 2:
SYMPOSIUM
SCHEDULE
159
EJISST2008 June 8~10
160
Layout of Audience Guide
Sunday - 2008 June 8
Time /Place
10.00 ~
12.00
12.00 ~
13.00
13.00~
13.45
13.45~14.00
14.00 ~
14.45
Room 501
Room 502
Room 602
Room 702
Room 503
Session 1:
NanotechnologyMaterials, -Process,
and – Products
ID Codes:
195, 219, 233, 283,
73, 80, 158, 176
Session 4:
BiotechnologyAgriculture - Food-1
ID Codes:
165, 202, 12, 44, 46,
161, 55
Session 5:
BiotechnologyMedicine-1
ID Codes:
62, 214, 238, 13, 35,
40, 48, 82
Session 6:
BiotechnologyPharmacy
ID Codes: 185, 11, 15,
33, 78, 107, 108, 110
Session 7:
Human Science
Japan foundation,
Prof. H. Akashi
ID Codes:
43, 65, 66, 124,
295,312
Session 5:
BiotechnologyMedicine-1
Session 6:
BiotechnologyPharmacy
Session 7:
Human Science
Prof. Y. Kite
ID Codes:
112, 122, 125, 123
ID Codes:
113, 135, 155, 175
ID Codes:
313, 314,316
LUNCH
Session 1:
NanotechnologyMaterials, -Process,
and – Products
ID Codes:
170, 204, 266
BREAK
Session 2:
Session 4:
BiotechnologyAgriculture - Food-1
ID Codes:
75, 87, 97, 104
BREAK
EJISST2008 June 8~10
Time /Place
14.15 ~
15.15
15.15 ~
15.30
15.30 ~
15.45
15.45 ~
16.00
16.00 ~
16.45
161
Room 501
Room 502
Room 602
Room 702
Room 503
Session 2:
Energy New
renewable EnergySolar, -Wind, and
Bio-energy
Session 4:
BiotechnologyAgriculture - Food-1
ID Codes:
126, 127, 138, 140
Session 5:
BiotechnologyMedicine-1
ID Codes:
129, 148, 147, 85
Session 6::
BiotechnologyPharmacy Session
ID Codes:
227, 200,, 217, 220
Session 7:
Human Science
ID Codes:
311, 317, 184, 315
ID Codes:
56, 142, 245, 14, 76,
131, 243
COFFEE BREAK
Session 3
:Manufacturing and
Quality- fabrication
of Electronic
Components
ID Codes:
183, 206, 210
COFFEE BREAK
Session 4:
BiotechnologyAgriculture - Food-1
Session 5:
BiotechnologyMedicine-1
Session 6:
BiotechnologyPharmacy
ID Codes:
141, 166, 162, 52
ID Codes:
167, 209, 218, 229
ID Codes:
303, 234, 240, 188, 321
Session 7:
Human Science
ID Codes:
318, 319, 320
EJISST2008 June 8~10
162
Layout of Audience Guide
Monday - 2008 June 9
Time/Place
9.00 ~ 10.00
10.00 ~
11.00
Hall 1 (Third Floor)
14.00 ~
14.15
Hall 3 Third Floor)
Big Hall Third Floor)
Registration
Opening Ceremony
H.E.Dr.Walid M. Abdelnasser
Dr. Katsuhiko Shirai
Dr. Ahmed B. Khairy
Keynote Speech
Hon.Mr. Koji Omi
Dr.Farouk Ismail
LAUNCH
11.00 ~
12.00
12.00 ~
13.00
13.00 ~
14.00
Hall 2 Third Floor)
Session 8:
Biotechnology- AgricultureFood-2
ID Codes:
215, 228, 237, 263
Session 9: BiotechnologyMedicine-2
ID Codes:
248, 260, 182, 257
BREAK
Session 10:
Health –Clinic and
Practice-2
ID Codes:
189, 168, 198, 222
Joint Projects and Invited
Talks
EJISST2008 June 8~10
Time/Place
14.15 ~
15.15
15.15 ~
15.30
15.30 ~
16.45
16.45 ~
17.00
17.00 ~
18.00
18.00 ~
18.30
163
Hall 1 (Third Floor)
Hall 2 Third Floor)
Session 8:
Biotechnology- AgricultureFood-2
ID Codes:
213, 196, 226, 178
Session 9:
Biotechnology-Medicine-2
Session 8:
Biotechnology- AgricultureFood-2
ID Codes:
231, 72, 208.264, 265
Session 9:
Session 11:
Biotechnology-Medicine-2
Health-Diagnosis and
Health Management -1
ID Codes:
294, 290, 305, 306, 308,
ID Codes:
309
137, 64, 150, 96, 54
BREAK
Session 8:
Biotechnology- AgricultureFood-2
ID Codes:
280, 282, 300
Hall 3 Third Floor)
Session 10:
Health –Clinic and
Practice-2
ID Codes:
ID Codes:
277, 278, 284
154, 310, 101, 117
COFFEE BREAK
Session 10:
Health –Clinic and
Practice-1
ID Codes:
6, 114, 152, 153
Session 11:
Health-Diagnosis and
Health Management-1
ID Codes:
145
Big Hall Third Floor)
Joint Projects and Invited
Talks
Joint Projects and Invited
Talks
Joint Projects and Invited
talks
EJISST2008 June 8~10
164
Layout of Audience Guide
Tuesday - 2008 June 10
Time/Place
9.00 ~ 10.00
Hall 1 ( Third Floor)
Session 12:
Health-Diagnosis and Health
Management-2
ID Codes:
149, 160, 216
BREAK
10.00 ~ 10.15
10.15 ~ 10.30
10.30 ~ 10.45
10.45 ~ 11.00
11.00 ~ 11.15
Session 13:
Information and
Communication Technology
(ICT), and Supercomputing
11.15 ~12.00
ID Codes:
271, 9, 236, 255, 88, 119, 132
12.00 ~ 13.00
Big Hall (First Floor)
Hall 2 ( Third Floor)
Hall 3 ( Third Floor)
Session 14:
Information and
Communication Technology
(ICT)
Session 15:
Civil and Environmental
Engineering-Earthquake
Geotechnical, and
-Air Pollution
Session 16:
Civil and Environmental
Engineering -Air Pollution
ID Codes:
190, 92, 93, 94, 106, 109
ID Codes: 79, 157, 177,
270, 273, 59
BREAK
Session 14:
Session 15:
Information and
Civil and Environmental
Communication Technology
Engineering-Earthquake
(ICT)
Geotechnical, and
-Air Pollution
ID Codes:
115, 116, 71, 269, 89
63, 84, 121, 134, 144
LUNCH
ID Codes:
246, 247, 181, 211, 279,
192, 36, 304
BREAK
Session 17:
Mechanical Engineering
ID Codes:
193, 235, 205
EJISST2008 June 8~10
Time/Place
Hall 1 ( Third Floor)
13.00 ~ 14.00
Session 13:
Information and
Communication Technology
(ICT), and Supercomputing
ID Codes:
133, 146, 156, 163
14.00 ~ 14.15
14.15 ~ 15.45
15.45 ~ 16.15
Session 13:
Information and
Communication Technology
(ICT), and Supercomputing
ID Codes:
223, 7, 37, 45,
165
Big Hall (First Floor)
Hall 2 ( Third Floor)
Session 14:
Session 15:
Information and
Civil and Environmental
Communication Technology
Engineering-Earthquake
(ICT)
Geotechnical, and
-Air Pollution
ID Codes: 221, 239,
244,252
169, 197, 203, 207
BREAK
Session 15:
Session 14:
Civil and Environmental
Information and
Engineering-Earthquake
Communication Technology
Geotechnical, and
(ICT)
-Air Pollution
ID Codes:
ID Codes:
256, 276, 307, 293
212, 262, 275, 286, 53, 57
CLOSING CEREMONY
Hall 3 ( Third Floor)
Session 17:
Mechanical Engineering
ID Codes:
120, 128, 201, 224
Session 17:
Mechanical Engineering
ID Codes:
251, 253, 301, 61, 199, 139
EJISST 2008 June 8~10
166
Time Table
Sunday - 2008 June 8
Pre-Session
SESSION 1: NANOTECHNOLOGY-MATERIALS, -PROCESS, AND –
PRODUCTS
ROOM (501) OKUMA TOWER BUILDING NUMBER 26
From
To
Serial
9.00
10.00
10.00
10.15
S1-1
10.15
10.30
S1-2
10.30
10.45
S1-3
10.45
11.00
S1-4
11.00
11.15
S1-5
11.15
11.30
S1-6
11.30
11.45
S1-7
11.45
12.00
S1-8
12.00
13.00
Titles and Authors
Registration
Design of low Young’s modulus Ti alloys
with high UTS for biomedical applications.
Mohamed Abdel-Hady and Masahiko
Morinaga, Nagoya University.
Characterization of Electrodeposited
Hydroxyapatite Coating on Nanoporous
Anodized Titanium. Fathy M. Bayoumi,
Madiha A. Shoeib and Hiroshi Nanjo,
RCCCP, Japan.
Electrochemical behavior of anodic film on
AZ31 mg alloy in 1M NaOH solution. S. A.
Salman, R. Ichino and M. Okido, Nagoya
University.
Ion Dynamics and Giant Dielectric Constant
in Pb1-xSnxF2 Solid Solutions. Mohamad M
Ahmad and Koji Yamada, Nihon University.
Investigation of Self Assembly Monolayer
(SAM) by using Second Harmonic
Microscopy (SHM) and Sum Frequency
Microscopy (SFM). Ahmed El Basaty and
Goro Mizutani, JAIST.
Application of Pulsed Power Technology to
Water-Solubilization of Carbon Nanotubes.
Usama Khaled and Junya Suehiro, Kyushu
University.
Novel pH-Sensitive Nanospheres for ColonSpecific Drug Delivery. Abdallah Mahmoud
Makhlof and Hirofumi Takeuchi, Gifu
Pharmaceutical University.
Preparation of new nanocomposite materials
based on layered double hydroxide.Mohamed
Reda Berber and Keiji Minagawa, University
of Tokushima.
LUNCH
Abstract
ID
195
219
233
283
073
080
158
176
EJISST 2008 June 8~10
167
13.00
13.15
S1-9
Formation of SiC MMC layer on Al alloys by
friction stir processing. Essam Rabea Ibrahim
Mahmoud and Kenji IKEUCHI, Osaka
University.
170
13.15
13.30
S1-10
204
13.30
13.45
S1-11
Iterative Learning Control based nonlinear
friction modeling in fast and precise
positioning control. Esam H. Abd-Elhameed
and Makoto Iwasaki, Nagoya Institute of
Technology.
Ion Transport Behavior in Diffusion Layer of
New Designed Ion Exchange-Mosaic
Composite Polymer Membrane. A. Mounir
EL Sayed and Akira Yamauchi, Kyushu
University.
13.45
14.00
266
BREAK
SESSION 2: NEW AND RENEWABLE ENERGY-SOLAR, -WIND, AND
BIO-ENERGY
ROOM (501) OKUMA TOWER BUILDING NUMBER 26
From
To
Serial
14.00
14.15
S2-1
14.15
14.30
S2-2
14.30
14.45
S2-3
14.45
15.00
S2-4
15.00
15.15
S2-5
15.15
15.30
S2-6
15.30
15.45
S2-7
Titles and Authors
Impacts of wind farms on the power system
quality and stabilIty. Omar Noureldeen and
Takashi Hiyama, Kumamoto University.
A Methodology for Designing and
Evaluating Biomass Utilization Networks.
Nasser Mohamed Abdelwahab Ayoub and
NakaYuji, Tokyo Institute of Technology.
DESIGN OF RENEWABLE ENERGY
SYSTEM IN AN EGYPTIAN SITE.
Abou-Hashema M. El-Sayed, Kyushu
University.
Laser Induced Magnesium Oxide Reduction
for Renewable Energy Cycle with Solar
Power. T. Yabe, S. Uchida, M.S. Mohamed,
C. Baasandash, Y. Sato, Y. Mori, and H.
Sato, Tokyo Institute of Technology.
Electrochemical deposition of indium
sulfide thin films for solar cell application.
Ashraf Abdel Haleem and M. Ichimura,
Nagoya Institute of Technology
Development of a DMFC Employing a
Novel Electrode Structure. Mohammad
Abdelkareem and Nobuyoshi Nakagawa,
Gunma university.
Intelligent Wind Turbine. Ahmed Mohamed
Galal and Toshiaki Kanemoto, Kyushu
Institute of Technology.
Abstract
ID
056
142
245
014
076
131
243
EJISST 2008 June 8~10
15.45
16.00
168
COFFEE BREAK
SESSION 3: MANUFACTURING AND QUALITY- FABRICATION OF
ELECTRONIC COMPONENTS
ROOM (501) OKUMA TOWER BUILDING NUMBER 26
From
To
Serial
16.00
16.15
S3-1
16.15
16.30
S3-2
16.30
16.45
S3-3
18:00
Titles and Authors
Application of the repulsive type magnetic
bearing technology based on digital control
implementation for manufacturing a micro
mass measurement system. Alaa A.
Hussien, Sotoshi Yamada, and Masayoshi
Iwahara, Kanazawa University.
Development of low noise RF front–end for
ultra-wideband (UWB) systems on 0.18um
CMOS Technology. Ahmed I. A. GALAL,
R. K. Pokharel, H. Kanaya and K. Yoshida,
Kyushu University.
Noise Reduction of Randomly Switched
DC-DC Converters by Digital Controller.
Gamal M. Dousoky, Masahito Shoyama
and Tamotsu Ninomiya, Kyushu University.
Abstract
ID
183
206
210
FREE TIME
SESSION 4: BIOTECHNOLOGY - AGRICULTURE - FOOD -1
ROOM 502 OKUMA TOWER BUILDING NUMBER 26
From
To
Serial
10.00
10.15
S4-1
10.15
10.30
S4-2
10.30
10.45
S4-3
Titles and Authors
Indirect 15N isotope techniques for
estimating rice N uptake from poultry
manure and sewage sludge. Adel Ghoneim
and Hideto Ueno, Ehime University.
Towards Integrated Water Management for
Sustainable Agricultural Development in
North Sinai, Egypt. W. H. Abou El Hassan,
Y. Kitamura and K. Shimizu, Tottori
University.
Application of Congo red agar to detect
Streptococcus dysgalactiae subsp.
dysgalactiae isolated from diseased fish.
Mohamed Abdelsalam and Terutoyo
Yoshida, University of Miyazaki.
Abstract
ID
165
202
012
EJISST 2008 June 8~10
From
To
Serial
11.00
11.15
S4-5
11.15
11.30
S4-6
11.30
11.45
S4-7
11.45
12.00
S4-8
12.00
13.00
13.00
13.15
S4-9
13.15
13.30
S4-10
13.30
13.45
S4-11
13.45
14.00
S4-12
14.00
14.15
14.15
14.30
S4-13
169
Titles and Authors
Characterization of Cytochrome P450
CYP1A in Ungulates. Wageh Sobhy
AbdElrahem, Mayumi Ishizuka, Kentaro
Sakamoto and Shoichi Fujita, Hokkaido
University.
Nanotechnology meets plant biotechnology:
Carbon Nanotubes deliver DNA and elicit
biochemical responses in plants. Maged
Fouad, Noritada Kaji, Manabu Tokeshi and
Yoshinobu Baba, Nagoya University.
Reconstruction of Iron-Oxidation Enzyme
System from the Rusticyanin, c-Type
Cytochrome and aa3-Type Cytochrome c
Oxidase of Sulfur-Grown Acidithiobacillus
ferrooxidans ATCC 23270. Taher M. Taha,
Tadayoshi Kanao, Fumiaki Takeuchi, and
Tsuyoshi Sugio, Okayama University.
First Characterization and Emergence of
SHV-60 in Raw Milk of a Healthy Cow in
Japan. Ahmed Moustafa Hammad and
Tadashi Shimamoto, Hiroshima University.
Abstract
ID
044
046
161
055
LUNCH
Taxonomic study of the subgenus
Lasioglossum s. str. of the genus
Lasioglossum (Hymenoptera, Halictidae) in
Japan. Mohamed A. Shebl, Ryuki Murao
and Osamu Tadauchi, Kyushu University.
Anti-babesial ellagic acid rhamnosides from
the bark of Elaeocarpus parvifolius.
Ahmed Elkhateeb and Hideyuki Matsuura,
Hokkaido University.
Identification and expression analysis of a
novel interleukin 8(IL-8)in carp(Cyprinus
carpio, L). Nevien Kamel Mohamed and
Miki Nakao, Kyushu University.
Functional characterization of the promoter
of a juvenile hormone-regulated gene,
Vitellogenin-2, from the cockroach
Periplaneta Americana.Azza Elgendy and
Makio Takeda, Kobe University.
BREAK
Studies on lactic acid production from xylan
by novel strains of marine lactic acid
bacteria, Halolactibacillus miurensis. Amira
M. Hamdan and Kenji Sonomoto, Kyushu
University.
075
087
097
104
126
EJISST 2008 June 8~10
From
170
To
Serial
Titles and Authors
14.30
14.45
S4-14
14.45
15.00
S4-15
15.00
15.15
S4-16
Studies on lactic acid production from
polysaccharides by novel lactic acid bacteria.
Abd El-Rahman, M.A, Keisuke Shibata,
Takeshi Zendo and Kenji Sonomoto, Kyushu
University.
Effects of anti-oxidative nutrients on
unloading-mediated expression of atrogenes.
Dalia Hemdan and Takashi Nikawa,
Tokushima University.
Monitoring Changes in the Arthropods
Biodiversity in Satoyama area with special
reference to Carabid Beetles as Bioindicators.
Wael Mahmoud El-Sayed and Nakamura Koji,
Kanazawa University.
15.15
15.30
15.30
15.45
S4-17
15.45
16.00
S4-18
16.00
16.15
S4-19
16.15
16.30
S4-20
16.30
18:00
16.45
-
Abstract
ID
127
138
140
COFFEE BREAK
Performance of the Cotton Leaf Worm
Spodoptera littoralis (Boisd.) (Lepidoptera:
Noctuidae) fed Cotton Plant Leaves
Gossypium barbadens (Malvaceae) grown
under Ambient 350 ppm and Enriched 700
ppm CO2 Regimes. Shahenda Abu El-Ela Ali
and Nakamura Koji, Kanazawa University.
Dynamics of carbon and nitrogen derived
from 13C and 15N dual-labeled compost in
continuously application in a vegetables soil.
Azza Ebid and Hideto UENO, Ehime
University.
Utilization of biotechnology for improving
abiotic stresses in cereals. Alhosein Hamada
Abd-El-Azeem and Takatoshi Tanisaka,
Kyoto University.
Fermented milk product prepared with
probiotic bacteria affects the onset of obesity
in rats. Essam M. Hamad, Ibrahim I. Abd ElGawad and Katsumi Imaizumi, Kyushu
University.
FREE TIME
141
166
162
52
EJISST 2008 June 8~10
171
SESSION 5: BIOTECHNOLOGY-MEDICINE-1
ROOM 602 OKUMA TOWER BUILDING NUMBER 26
From
To
Serial
10.00
10.15
S5-1
10.15
10.30
S5-2
10.30
10.45
S5-3
10.45
11.00
S5-4
11.00
11.15
S5-5
11.15
11.30
S5-6
11.30
11.45
S5-7
11.45
12.00
S5-8
12.00
13.00
Titles and Authors
Branchial Sodium- Potassium ATPase
enzyme activity of Mitochondrion-rich cells
In Mozambique tilapia in response to
Osmotic changes. Sameh Magdeldin
Mohamed and Yamamoto tadashi, Niigata
University.
Monocarboxylate Transporter 1 (MCT1) in
the Gastrointestinal Tract of Ruminants.
Doaa Kirat and Seiyu Kato, Rakuno Gakuen
University.
Pathological study on the scuticociliatosis
affecting natural and farmed Bastard Halibut
(Paralichthys olivacus)in Tottori prefecture,
Japan. EMAN M. MOUSTAFA, A.
SHIMADA, and T. MORITA, Tottori
University.
In Vitro Expression of Natriuretic Peptides in
Cardiomyocytes Differentiated from Monkey
Embryonic Stem Cells. Essam Mohamed
Abdelalim and Ikuo Tooyama, Shiga
University of Medical Science.
Ki-67, p53 and Epidermal Growth Factor
Receptor expression in early laryngeal cancer
treated with radiotherapy. Wael A. Ahmed
and Kenji Suzuki, Fujita Health University.
Evidence of linkage on chromosomes 4q28
and 7q in a genome-wide linkage scan for
comitant strabismus susceptibility loci among
Japanese families. Sherin Elsayed Shaaban
and Toshihiko Matsuo, Okayama University.
Molecular Characterization of PVL-Positive
Staphylococcus aureus isolated from Egypt.
Shymaa Enany and Tatsuo Yamamoto,
Niigata University.
Deep brain simulation for Parkinson disease.
Mohamed Ali, Youichi Saitoh, Koichi
Hosomi Haruhiko Kishima, Satoru Oshino,
Masayuki Hirata and Toshiki Yoshimine,
Osaka University.
LUNCH
Abstract
ID
062
214
238
013
035
040
048
082
EJISST 2008 June 8~10
13.00
13.15
S5-9
13.15
13.30
S5-10
13.30
13.45
S5-11
13.45
14.00
S5-12
14.00
14.15
14.15
14.30
S5-13
14.30
14.45
S5-14
14.45
15.00
S5-15
15.00
15.15
S5-16
15.15
15.30
15.30
5.45
S5-17
15.45
16.00
S5-18
16.00
16.15
S5-19
172
Analyses of the propagation of canine
distemper viruses (CDVs) in HmLu hamster
cells. Serag El-Deen Sultan and Kazushige
Kai, Yamaguchi University.
Characterization of a minor human NK cell
sub-population, CD56dim16-cells. Omar
Dessouki and Seiji Okada, Kumamoto
University.
Molecular epidemiological study on Hepatitis
viruses in Ismailia Egypt. Ahmed Ibrahim
Youssef and Yoshitak Hayashi, Kobe
University.
AP-1 and NF-κB are key regulators of TollLike Receptor 3 signaling pathway: an in
silico prediction. Mohamed Helmy, Masaru
Tomita, Masa Tsuchiya and Kumar
Selvarajoo, Keio University.
112
122
125
123
BREAK
Identification of cells that have hematopoietic
activity in the placenta of mouse embryo.
Gomaa Ahmed and Taga Tetsuya,
Kumamoto University.
Effect of local soft x-ray irradiation on rat
skin: to establish radiation-impaired wound
healing model. Ayman Atiba, Hiroshi Ueno
and Yuji Uzuka, Gifu University.
The Detection of Autophagy and Apoptosis
in Pancreatic Beta Cells to Investigate the
Contribution of Autophagy for Islets to
Survive During Isolation and Transplantation
Hamed Elgendy, Teru Okitsu and Kazuhiko
Fukuda, Kyoto University Hospital.
The role of PROPELLER Diffusion
Weighted Imaging and Apparent diffusion
coefficient in the diagnosis of sellar and
parasellar lesions. Omar Mostafa Mahmoud
and Kaoru Kurisu, Hiroshima University.
129
148
147
085
COFFEE BREAK
Migration inhibitory factor and neuclear
factor kabba B expression after laparotomy
and pneumoperitoneum. Anwar Tawfik Amin
Ali and S. Kitano, Oita University.
Species differentiation of eimerian oocysts in
farms where no clinical coccidiosis is noted.
Nabila Osman and Hiroshi Sato,Yamaguchi
University.
Some morphological studies on the visual
system of albino and pigmented rat. Safwat
A. M. A., T. Imagawa and M. Uehara, Tottori
University.
167
209
218
EJISST 2008 June 8~10
16.15
16.30
16.30
16.45
-
18:00
S5-20
173
The significance of rDNA sequence and
lipopolysaccharide in the pathology and
biotechnology of Agrobacterium species.
Hussam Hassan Arafat Hassan, J-ney
Bautista-Zapanta, Katsuyuki Tanaka
Hiroyuki Sawada and Katsunori Suzuki,
Hiroshima University.
229
FREE TIME
SESSION 6 : BIOTECHNOLOGY-PHARMACY
ROOM 702 OKUMA TOWER BUILDING NUMBER 26
From
To
Serial
10.00
10.15
S6-1
10.15
10.30
S6-2
10.30
10.45
S6-3
10.45
11.00
S6-4
11.00
11.15
S6-5
11.15
11.30
S6-6
11.30
11.45
S6-7
Titles and Authors
Total Synthesis of Kahalalide F Toward
Elucidation of the biological function
concerning the oceanic production reason of
active peptides which are recently discovered.
Mostafa Ahmed Sabet Ahmed Hammam and
Uemura Daisuke, Nagoya University
Plasmodium falciparum Guanosine
Monophosphate Kinase:A New Target for the
Development of Anti-Malarial Drugs.
Mahmoud Kandeel and Yukio Kitade, Gifu
University.
Prolongation of residence time of liposome
by surface- modification with mixture of
hydrophilic polymers. Tamer Mohamed
Shehata, Ken-ichi Ogawara, Kazutaka Higaki
and Toshikiro Kimura, Okayama University.
Proteome approach for identification of
Schistosomiasis japonica vaccine candidate
antigen. Ekhlas Hamed Abdel-Hafeez and
Kenji Hirayama, Nagasaki University.
Two new biologically active compounds
from marine fungi. Ahmed Atef El-beih,
Sachiko Tsukamoto and Tomihisa Ohta,
Kanazawa University
A novel approach using functional peptides
for efficient nasal absorption of insulin.
El-Sayed Abdou Khafay Mariko Morishita
and Kozo Takayama, Hoshi University.
Highly sensitive and selective HPLC method
with peroxyoxalate chemiluminescence
detection for the determination of
doxorubicin and its metabolite doxorubicinol
in rat plasma. Sameh Abdel-Raouf Ahmed
and Naotaka Kuroda, Nagasaki University.
Abstract
ID
185
011
015
033
078
107
108
EJISST 2008 June 8~10
From
To
Serial
174
Titles and Authors
11.45
12.00
S6-8
Antitumor hydrolysable tannins from wildly
growing plant, Tamarix nilotica, in the
Egyptian oases. Mohamed A. A. Orabi,
Shoko Taniguchi and Tsutomu Hatano,
Okayama University.
12.00
13.00
13.00
13.15
S6-9
13.15
13.30
S6-10
13.30
13.45
S6-11
13.45
14.00
S6-12
Amidophosphane–Copper(I)-Catalyzed
Asymmetric Conjugate Addition of
Dialkylzincs to Racemic 6-Substituted
Cyclohexenones to Form 2,5-Di- and 2,2,5Trisubstituted Cyclohexanones. Khalid B.
Selim and Kiyoshi Tomioka, Kyoto
University.
MODULATION OF GENE EXPRESSION
BY HUMAN CYTOSOLIC tRNase ZL
THROUGH SMALL NONCODING RNA.
Reyad Elbarbary and Masayuki Nashimoto,
Niigata University of Pharmacy and Applied
Life Sciences.
Synthesis and properties of 1’-disubstituted
Nucleoside Analogues. Tamer M. Nasr,
Yosuke Taniguchi and Shigeki Sasaki,
Kyushu University.
Modulatory effects of 5-Fluorouracil on the
rhythmic expression of circadian clock gene:
a possible mechanism for chemotherapyinduced circadian rhythm disturbances.
Ahmed M. Hamdan and Ohdo Shigehiero,
Kyushu University.
14.00
14.15
14.15
14.30
S6-13
14.30
14.45
S6-14
14.45
15.00
S6-15
15.00
15.15
S6-16
15.15
15.30
Abstract
ID
110
LUNCH
113
135
155
175
BREAK
Importance Of D-Amino Acid Oxidase
Enzyme In Biotechnology. Rabab M. Abou
El-Magd and Kiyoshi Fukui, The University
of Tokushima.
The effects of extracellular acidic
environments on T-cell differentiation.
Amany abdelrehim bekhit and Hiroshi
Kobayashi, Chiba University.
New sesquiterpene lactones from Daucus
glaber (Forssk.) Tell. F. Umbelliferae.
Amal Ahmed Atwa Sallam and Koichi
Takeya, Yokyo University of Pharmacy and
Life Sciences.
Role of β-Hydroxy--Trimethylammonium
Butyrate and Ubiquinone in Combating the
Deteriorative Effect Induced by CCl4 in Rat’s
Liver. Asmaa M. Bayoumi , Atef E. Abd ElBaky, Sanaa A. Ali and Laila M. Faddah,
Kyushu University.
COFFEE BREAK
227
200
217
220
EJISST 2008 June 8~10
175
15.30
15.45
S6-17
15.45
16.00
S6-18
16.00
16.15
S6-19
16.15
16.30
S6-20
16.30
16.45
S6-21
18:00
-
Diagnosis of human malaria parasites in
mosquitoes. Omar Sayed Omar and Yusuke
wataya, Okayama University.
Total Synthesis of Aza Analogues of
Flustramide alkaloids by Using Aza PausonKhand Reaction. Yaseen A. Mosa and C.
Mukai, Kanazawa University.
Utilization of cell penetrating peptides for
enhancing intracellular delivery of nucleic
acids encapsulated into liposomes:
Octaarginine versus octalysine. Ayman ElSayed, Ikramy A Khalil, Kentaro Kogure and
Hideyoshi Harashima, Hokkaido University.
A new Route to Synthesis of Biologically
Active Azaindoles. Montaser Shaykoon
Ahmed and C. Mukai, Kanazawa University.
Recombinant Human Growth Hormone
(rHGH) Production. Hanna Hammad,
Theodour Bilharz Research Institute.
303
234
240
188
321
FREE TIME
SESSION 7: HUMAN SCIENCE
ROOM (503) OKUMA TOWER BUILDING NUMBER 26
From
10.00
10.15
To
10.15
10.30
Serial
S7-1
S7-2
10.30
10.45
S7-3
10.45
11.00
S7-4
Titles and Authors
Japan Foundation presentation
For Interchange and Collaboration between
Islamic Economics and Buddhist Economics.
Hiroyuki Akashi, Professor, (Former Director
of International Center of Komazawa
University), Faculty of Business
Administration, Komazawa University.
Policy Networks and Public Policy Making
Process: A Comparative Analysis to the
Education Policy Reforms and the ODA
Policy Reforms in Japan during the 1980s and
the 1990s. Ahmed M. Abd Rabou, Hokkaido
University.
Social policies in Egypt and how subsidies
system can be rationalized to benefit the poor.
Maha Ahmed Khalil and Tanaka Hideaki,
National Graduate Institute for Policy
Studies.
Abstract
ID
Invited
Talk
043
065
EJISST 2008 June 8~10
From
To
Serial
11.00
11.15
S7-5
11.15
11.30
S7-6
11.30
11.45
S7-7
11.45
12.00
S7-8
12.00
13.00
13.00
13.15
176
Titles and Authors
Environmental Security in the International
Politics: A Comparative Study between
Japanese and American Policies. Nilly
Kamal El-Amir and Fukagawa Yukiko,
Waseda University.
A Study about Interference of Mother
Language and Misuse Analysis in the
Second Language Acquisition. Mohammad
Ebdel-Rahman Eshiba and Satoshi
MIYAZAKI, Waseda University.
中世文学における地獄と浄土の夢
Yousra Ashraf Mohamed Anwar and
Tanaka Takako, Konan University.
宮沢賢治の文学における「孤独感」
Amira Said Aly and Hiraishi Noriko
Tsukuba University.
Abstract
ID
066
124
295
312
LUNCH
S7-9
13.15
13.30
S7-10
13.30
13.45
S7-11
13.45
14.00
S7-12
14.00
14.15
14.15
14.30
S7-13
14.30
14.45
S7-14
14.45
15.00
S7-15
Japanese Studies at Kansai University:
Globalizing Our Campus. Yuriko Kite
Director, Center for International Affairs,
Professor, Institute of foreign Language
Education and Research, Kansai University
Japanese Language Culture - Language
Hala Mahmoud Abd Elazim and
Matsumura Yoshiko, Kyushyu University.
Modern Literature and Gender- Japanese
Literature. Mohamed Momtaz Mohamed
and Hirata Yumi, Osaka University.
Higher Education Privatization and the
Planning for Educational Reform: Malaysia
as a Case Study 1996-2006. Ahmed
Mohamed Nabawy and Kleinschmidt
Harald, Tsukuba University.
Invited
Talk
313
314
316
BREAK
福沢諭吉とムハンマド･アブドウの教育
思想.
-教育と政治の分立論をめぐって
Harb Hassan Kamal and Takamitu
Shimamoto, Osaka University.
“Continuity and Discontinuity in Japanese
Foreign Policy toward the Middle East: The
Persian Gulf Wars” as a case study. Abeer
yassin and Masataka kimura, Ibaraki
University.
Japanese demonstratives. Yasmine Samy
Gamal ElDin and Ken Machida,
Nagoya University.
311
317
184
EJISST 2008 June 8~10
15.00
15.15
15.15
15.30
15.30
15.45
S7-16
177
イスラム教．仏教における死後の世界.
Reem Ahmed Saleh and Shimazono
Susumu, Tokyo University
315
COFFEE BREAK
S7-17
日本語とアラビア語の慣用表現の意味
と概念的メタファーのメカニズム
318
―生、死、時、喜、哀を中心に―
15.45
16.00
S7-18
16.00
16.15
S7-19
16.15
16.30
16.30
16.45
-
18:00
Almoamen Abdalla, Gakushuin University.
" 日本現代思想におけるイスラム研究”
.Nermeen Ezz Eldin Mansour and Miura
Touru, Ochanomizu University.
”現代日本語における動詞の意志性（
意志動詞、無意志動詞”. Afaf Emad
Aboulhoda and Hayatsu Emiko, Tokyo
University for foreign studies.
FREE TIME
319
320
EJISST 2008 June 8~10
178
Opening Session
Monday – 2008 June 9
9.00
10.00
10.00
11.00
Registration
Opening Ceremony
Welcome Addresses:
H.E. Dr. Walid Mahmoud Abdelnasser
Ambassador of the Arab Republic of Egypt to Japan
Dr. Katsuhiko Shirai
President, WASEDA University
Inauguration Address:
Dr. Ahmed B. Khairy
First Under-Secretary for Culture Affairs and Missions,
Ministry of Higher Education and State for Scientific
Research, Egypt.
11:00
11:30
Keynote Speech (Japanese)
Hon. Mr. Koji Omi
Former Minister of Finance of Japan,
Member of the House of Representatives,
Founder and Chairman of the Science and Technology in
Society forum (STS forum)
11:30
12.00
Keynote Speech (Egyptian)
Dr. Farouk Ismail
Former President of Cairo University,
Member of the Shoura Council,
President of Ahram Canadian University
and Honorary President of the Association of
Japanese University Graduates and Researchers.
12.00
13.00
LUNCH
EJISST 2008 June 8~10
179
Joint Projects and Invited Talks Session
JOINT PROJECTS AND INVITED TALKS
IBUKA CONFERENCE BIG HALL (FIRST FLOOR)
From
13.00
To
13.15
Serial
Ji-1
13.15
13.30
Ji-2
13.30
13.45
Ji-3
13.45
14.00
Ji-4
14.00
14.15
14.15
14.30
Ji-5
14.30
14.45
Ji-6
14.45
15.00
Ji-7
15.00
15.15
JI-8
15.15
15.30
15.30
15.45
Ji-9
15.45
16.00
Ji-10
Titles and Authors
International Cooperation between Egypt and Japan:
- EJUST：A Breakthrough University of Science and
Technology - Manabu TSUNODA, Dr. Eng.,
Senior Advisor (Higher and Technical Education),
Japan International Cooperation Agency (JICA).
Heat-Directed Composite Materials: From Concept to
Aerospace Applications. Mohamed S. Aly-Hassan,
Institute of Space and Astronautical Science (ISAS),
Japan Aerospace Exploration Agency (JAXA).
Conservation Activities of "Egyptian-Japanese Mission
for the Mastaba Idout" (2005-2007). Hiroshi Suita,
Tadateru Nishiura, Masaaki Sawada, Iwataro Oka,
Ahmed S. Shoeib and Adel. I. Akarish, Kansai
University.
Stability Investigation of Mother Rock in a Pharaonic
Mastaba (Saqqara) for its Conservation of Mural
Paintings. Tatsuaki Nishigata, Atsushi Ito, Tadateru
Nishiura, Ahmed S. Shoeib, Adel I. Akarish and Hiroshi
Suita, Kansai University.
BREAK
Towards academic exchange and cooperation between
NWRC and TU. Hattori Kunio and Waleed H. Abou El
Hassan, Department of Irrigation & Drainage Water
Management, Tottori University.
Seismological Observation in and around the Southern
Part of the Gulf of Suez, Egypt. Nobuo Hurukawa,
International Institute of Seismology and Earthquake
Engineering (IISEE), Building Research Institute,
Tsukuba.
A window to the ancient Earth: Pan-African ophiolites of
Proterozoic age from Southeastern Desert, Egypt.
Shoji Arai, Kanazawa University.
Future World Water Assessment through System
Dynamics. Toshiharu Kojiri, Junpei Nakatuska and TengSheng Chong, Water Resources Research Center, DPRI,
Kyoto University.
COFFEE BREAK
Liver Cancer in Egypt and an Experience of
Collaboration in Cancer Treatment. Hiroshi Maeda,
Professor, Faculty of Pharmaceutical Science, Sojo
University, Kumamoto.
MEMS/MS and Assembly as Key Components and
Technology for Advanced System. Osamu Tabata,
Graduate School of Engineering, Kyoto University.
EJISST 2008 June 8~10
From
16.00
To
16.15
Serial
Ji-11
16.15
16.30
Ji-12
16.30
16.45
Ji-13
16.45
17.00
17.00
17.15
Ji-14
17.15
17.30
Ji-15
17.30
17.45
Ji-16
17.45
18.00
JI-17
18.00
18.15
Ji-18
18.15
18.30
Ji-19
180
Titles and Authors
Nucleosides, nucleotides and nucleic acids: chemistry and
biology. Yukio Kitade, United Graduate School of Drug
Discovery and Medicinal Information Sciences, Center
for Advanced Drug Research, Department of
Biomolecular Science, Faculty of Engineering,
Gifu University.
Characterization and Expression of the Insect-Specific
Scorpion Neurotoxins for Pest Control. Mohamed A. Abd
El-Rahman and Hitoshi Ueda, Zoology Department,
Faculty of Science, Suez Canal University, Ismailia,
Egypt.
Tumor Necrosis Factor Receptors on Lymphoma Cells in
Enzootic Bovine Leukosis. KOSUKE OKADA,
MANABU IKEDA, SATORU KONNAI, MISAO
ONUMA, NAOTAKA ISHIGURO, and MASANOBU
GORYO, Department of Pathogenic Veterinary Science,
The United Graduate School of Veterinary Sciences, Gifu
University,Department of Veterinary Pathology, Faculty
of Agriculture, Iwate University.
BREAK
Optical Sum Frequency Microscopy for Botanical
Analysis. Goro Mizutani, Yoshihiro Miyauchi, and
Haruyuki Sano, School of Materials Science, Japan
Advanced Institute of Science and Technology, CREST,
Japan Science and Technology Agency.
Atomic scale flattening of oxide thin film formed on
metals. Hiroshi Nanjo and Fathy M. Bayoumi,
RC-CCP, AIST.
Possible applications of solid electrolyte to lithium
secondary battery, sensor and supercapacitor.
Koji Yamada, Applied Molecular Chemistry
College of Industrial Technology, Nihon University.
Joint Research Work between:Toyohashi University of
Technology and Assiut University, Electrostatic
precipitation, as an important environmental technology.
Akira Mizuno, Toyohashi University of Technology.
Experience with Plastic Surgery In Ain Shams University
and prospects of cooperation with the Japanese
Universities. Amr Mabrouk, Professor of Plastic surgery,
Ain Shams University, Egypt.
Japan Society for the Promotion Science ( JSPS)
Presentation
EJISST 2008 June 8~10
181
Monday – 2008 June 9
Technical Sessions
SESSION 8: BIOTECHNOLOGY - AGRICULTURE - FOOD-2
IBUKA CONFERENCE HALL 1 (THIRD FLOOR)
From
To
Serial
13.00
13.15
S8-1
13.15
13.30
S8-2
13.30
13.45
S8-3
13.45
14.00
S8-4
14.00
14.15
14.15
14.30
S8-5
14.30
14.45
S8-6
14.45
15.00
S8-7
15.00
15.15
S8-8
15.15
15.30
15.30
15.45
Titles and Authors
Microbiological, Chemical, sensory and shelf
life evaluation of sliced salmon treated with
salts of organic acids. Khalid Ibrahim Sallam,
AIST.
Colistin susceptibility, pharmacokinetics, and
residues in broilers and laying hens. Waleed
Fathy Khalil, Dalia H. Mansour and Shimoda
Minoru, Tokyo University of Agriculture and
Technology.
Implementation Degree of Agricultural
Decisions in the farm Level: Comparison
Study between Egypt and Japan. Adel I. Ali
and Teuraki Nanseki, Kyushu University.
EVALUATION OF NATURAL
ANTIOXIDANTS EXTRACTED FROM
DIFFERENT AGRO-INDUSTRIAL BY
PRODUCTS. Sahar R. Abd El-Hady and
Tashiro Matsui, Kyushu University.
Abstract
ID
215
228
237
263
BREAK
Regulation of developmental timing by
transcription factors in Drosophila
melanogaste. Moustafa Mohamed Hemida
Sarhan and Ueda Hitoshi, Okayama
University.
A 450-kb B chromosome in a filamentous
ascomycete Nectria haematococca mating
population I (anamoph, Fusarium solani f.
sp. cucurbitae). Ahmed Mohamed Mahmoud
and Masatoki Taga, Okayama University.
Expression and functions of retinol binding
protein 4 in bovine adipocytes. Mabrouk A.
Abd Eldaim and Kazuhiro Kimur, Hokkaido
University.
New Selective cytotoxic compounds from
zizyphus spina christi L. Mahmoud Abdalla,
Fumihide Takano and Tomihisa Ohta,
Kanazawa University.
213
196
226
178
COFFEE BREAK
S8-9
Bio-surface modification of some oxide
minerals and its application in minerals
separation. Mohsen Mohammad Farahat and
Tsuyoshi Hirajima, Kyushu University.
231
EJISST 2008 June 8~10
From
To
Serial
15.45
16.00
S8-10
16.00
16.15
S8-11
16.15
16.30
S8-12
16.30
16.45
S8-13
16.45
17.00
17.00
17.15
S8-14
17.15
17.30
S8-15
17.30
17.45
S8-16
17.45
18.00
182
Titles and Authors
Biotechnological studies on halophilic
bacteria isolated from Egyptian salt lakes.
Omneya Abd El Hafez and Shinichi Nagata,
Kobe University.
Effect of high temperature on sex
differentiation and germ cell population in
medaka, Oryzias latipes. Khaled M. Selim,
Ai Shinomiya, Hiroyuki Otake, Satoshi
Hamaguchi and Mitsuru Sakaizumi, Niigata
University.
Immunohistochemical investigation for
arthropod brain design and the functional
relationship to the mid gut system.
Maged Fouda, Kobe University.
Characterization of a novel dehalogenase
involved in 2-chloroacrylic acid metabolism
in Pseudomonas sp. YL. Amr Mohammed
Hassan and ESAKI, Nobuyoshi, Kyoto
university.
Abstract
ID
072
208
264
265
BREAK
Establishment of regeneration and
transformation protocol for Anthurium
andreaum. Nader ahmed mohmed darwish
and Masahiro Mii, Chiba university.
Development of live attenuated vaccine for
Edwardsiella tarda infection in fish.
Alkhateib Y. Gaafar and Toshihiro Nakai,
Hiroshima University.
Microbiological Quality of Some Egyptian
Meat Products. Mahmoud Mohammed,
Takeshi Honda and Mohammed Elgazzar,
Osaka University.
280
282
300
SESSION 9 : BIOTECHNOLOGY-MEDICINE-2
IBUKA CONFERENCE HALL 2 ( THIRD FLOOR)
From
13.00
To
13.15
Serial
S9-1
Titles and Authors
Gene Expression Profiles in High and Low
Metastatic Potential Lung Cancer Cell Lines,
a cDNA Microarray-Based Study. Ashraf A.
Ewis, Kazuya Kondo, Yasuo Shinohara,
Mitsuru Ishikawa, Yoshinobu Baba, and
Yutaka Nakahori, the University of
Tokushima.
Abstract
ID
248
EJISST 2008 June 8~10
From
To
Serial
13.15
13.30
S9-2
13.30
13.45
S9-3
13.45
14.00
S9-4
14.00
14.15
14.15
14.30
S9-5
14.30
14.45
S9-6
14.45
15.00
S9-7
15.00
15.15
S9-8
15.15
15.30
15.30
15.45
S9-9
15.45
16.00
S9-10
16.00
16.15
S9-11
16.15
16.30
S9-12
183
Titles and Authors
An efficient in-vitro model for the study of
natural Hepatitis C virus infection. Hussein
Hassan Aly and Makoto Hijikata, Kyoto
University.
Increased Intestinal Endotoxin Absorption
during Enteric Nematode but not Protozoal
Infections through a Mast Cell-Mediated
Mechanism. Ayman Samir Farid and
Yoichiro Horii, University of Miyazaki.
The role of membrane type1- matrix
metalloproteinase ( MT1-MMP) in cancer
ivasion and metastasis. Moustafa sakr and
Hiroshi Sato, Kanazawa University.
Abstract
ID
260
182
257
BREAK
Chk1 is a histone H3-T11 kinase that
regulates DNA damage-induced
transcriptional repression. Doaa Hussein
Zineldeen and Makoto Nakanishi, Nagoya
City University.
Virological and clinical implication of core
promoter C1752/V1753 and T1764/G1766
mutations in hepatitis B virus genotype D
infection. Abeer Abd elRaheem Ahmed and
Masashi Mizokami, Nagoya City University.
Facial Nerve Injury induces activation of
NF-kB in rat facial nucleus. Majid Mohamed
Safwat Hafez and Shingo Murakami,
Nagoya City University.
Effect of two housing systems and stocking
density on White New Zealand Rabbit.
TAREK M. M. BALABEL, Tottori
University.
277
278
284
294
COFFEE BREAK
Treatment of scaphoid nonunion with dorsal
transplantation of vascularized bone grafts.
Ahmed Naeem Atiyya and Ryosuke
Kakinoki, Kyoto University.
Comparative Study between Open and
Laparoscopic Distal Pancreatectomy.
Mohammed Yahia Farrag and Shuji
Shimizu, Kyushu University.
Caspase activation role in the antiviral
treatment response in chronic hepatitis C
virus infection. Walaa Hassan, Norihiro
Furusyo and Jun Hayashi, Kyushu
University.
The role of CFTR protein in intestinal
epithelial cell function and cystic fibrosis.
Aziz Awaad Aziz Mohamed and Kazunori
Ishimura, The Tokushima of University.
290
305
306
308
EJISST 2008 June 8~10
16.30
16.45
16.45
17.00
S9-13
184
Expression of cytokine genes in head kidney
and spleen cells of Japanese flounder
infected with N. seriolae. Mahmoud
Tanekhy Amer and Masahiro Sakai,
Miyazaki University.
309
BREAK
SESSION 10: HEALTH –CLINIC AND PRACTICE-1
IBUKA CONFERENCE HALL 2 ( THIRD FLOOR)
From
To
Serial
Titles and Authors
Photoprotective effects of chemical peeling
agents against ultraviolet-induced
photoaging in hairless mice. Mohamed
Abdel-Daim, Yoko Funasaka, Hiroshi
Matsunaka*, Masahiko Ooe* and Chikako
Nishigori, Kobe University.
Predictors of short and long-term survival
after adult living donor liver transplantation.
Walid Mohamed El Moghazy, Shinji
Uemoto and Akio Koizumi, Kyoto
University.
Immunohistochemical expression of ATX
and AGK in Prostate Cancer with relevance
to Clinicopathological parameters.
Mohammed Ahmed Abdel Muneem Nouh
and Yoshiyuki Kakehi, Kagawa University.
Human scavenger receptor class B type I is
regulated by activators of Peroxisome
proliferators-activated receptor- in
hepatocytes. Rania Abdel Muneem Ahmed
and Toshihiko Ishida, Kagawa University.
17.00
17.15
S10-1
17.15
17.30
S10-2
17.30
17.45
S10-3
17.45
18.00
S10-4
Abstract
ID
006
114
152
153
SESSION 10: HEALTH –CLINIC AND PRACTICE -2
IBUKA CONFERENCE HALL 3 ( THIRD FLOOR)
From
13.00
To
13.15
Serial
S10-5
Titles and Authors
The Sex Differences of Cerebrospinal Fluid
levels of Interleukin-8 and Antioxidants in
Asphyxiated Newborns. Mohamed Hamed
Hussein, Ghada A. Daoud, Hisanori
Sobajima and Hajime Togari, Nagoya
University.
Abstract
ID
189
EJISST 2008 June 8~10
13.15
13.30
S10-6
13.30
13.45
S10-7
13.45
14.00
S10-8
14.00
14.15
14.15
14.30
S10-9
14.30
14.45
S10-10
14.45
15.00
S10-11
15.00
15.15
S10-12
15.15
15.30
185
Novel role of HMG-CoA reductase inhibitor
in keratinocyte proliferation and migration.
Mostafa Ibrahim Attia, I. Katayama and H.
Murota, Osaka University.
Molecular biological studies on cancer gene
therapy: regulation of apoptosis and
metabolosim. Salah M. elSayed and
K.Fukui, Tokushima University.
Pediatrics cardiology. Manal M. Helmy
Nabo and Shoji Kagami, Tokushima
University.
168
198
222
BREAK
Evaluation of Coronary Calcium Score by
Multidetector Computed Tomography in
Relation to Endothelial Function and
Inflammatory Markers in Asymptomatic
Individuals. Mahmoud Ramadan
Mohammed and Yoshifusa Aizawa, Niigata
University.
Utilization of Polymethyle-methacrylate
(PMMA) interposition as an alternative to
the different modalities of cervical interbody
fusion for treatment of single level cervical
disc disease. Tamer I. Orief and Masakazu
Takayasu, Aichi Medical University School
of Medicine.
Various reconstructive modalities for
diabetic foot ulcer. Ahmed Kamal Osman
and Nakanishi H.,Tokushima University
Two different techniques for donor hepatic
transection: CUSA with Bipolar cautery
versus CUSA with TissueLink™. A
randomized controlled trial. Mohammed
Saied Abo Hedaya and Shinji Uemoto,
Kyoto University.
154
310
101
117
COFFEE BREAK
SESSION 11: HEALTH-DIAGNOSIS AND HEALTH MANAGEMENT-1
IBUKA CONFERENCE HALL 3 ( THIRD FLOOR)
From
15.30
To
15.45
Serial
S11-1
Titles and Authors
Research on genetics of respiratory diseases
in Japanese and Egyptian populations, Lung
mucus , regeneration with HGF and stem
cells. Ahmed Hegab and Mutsuo Yamaya,
Tohoku University.
Abstract
ID
137
EJISST 2008 June 8~10
15.45
16.00
S11-2
16.00
16.15
S11-3
16.15
16.30
S11-4
16.30
16.45
S11-5
16.45
17.00
17.00
17.15
S11-6
186
Mechanisms of Enhancement of TRAIL
Tumoricidal Activity Against Human Cancer
Cells of Different Origin by Dipyridamole.
Ahmed Elsayed Goda and Toshiyuki Sakai,
Kyoto Prefectural University of Medicine.
Bacteriocin production in the compost
process. Hosnia Abdel-Mohsein and Nakai
Yutaka, Tohoku University.
Percutaneous Treatment of HCC. Hamdy
Saad Mohammed, Ali Taha Ali Hassan, Adel
A. El-Sayed and Tsutomu Masaki, Kagawa
University.
NERVE TRANSFER TO DELTOID
MUSCLE USING THE MOTOR
BRANCHES OF THE TRICEPS MUSCLE
AFTER UPPER BRACHIAL PLEXUS
AVULSION INJURIES. Waleed Riad Saleh
and Hiroshi Yajima, Nara Medical
University.
064
150
096
054
BREAK
Analyses of Fluourotelomer alcohols
(FTOHs) in surface waters using Gas
chromatography- Mass spectrometry (GCMS). Manal AM Mahmoud, Kyoto
University.
145
EJISST 2008 June 8~10
187
Tuesday - 2008 June 10
Technical Session
SESSION 12 :HEALTH-DIAGNOSIS AND HEALTH MANAGEMENT-2
IBUKA CONFERENCE HALL 1 (THIRD FLOOR)
From
To
Serial
Titles and Authors
Endoscopic Ultrasound Fine Needle
Aspiration (EUS-FNA) and Endoscopic
Retrograde Cholangiopanreatography
(ERCP) Brush Cytology in Diagnosis of
Biliary and Pancreatic Duct Strictures. Wael
A. Abbas, Mohamed Ali Tohamy and Kenji
Yamao, Aichi Cancer Center Hospital.
A New Era for the Dry Eye Diagnosis.
Osama M.A. Ibrahim, Murat Dogru and
Kazuo Tsubota, Keio University School of
Medicine.
Chemoprevention and theraputic treatment of
basal cell carcinoma (BCC). Moshira M.
Hassan and Arase S., Tokushima
University.
9.00
9.15
S12-1
9.15
9.30
S12-2
9.30
9.45
S12-3
9.45
10.00
10.00
10.15
S12-4
Abstract
ID
149
160
216
.
BREAK
SESSION 13: INFORMATION AND COMMUNICATION
TECHNOLOGY (ICT), AND SUPERCOMPUTING
IBUKA CONFERENCE HALL 1 (THIRD FLOOR)
From
To
Serial
Titles and Authors
Embedded Systems Design and Technology.
Mona A. Abo El-Dahb and Yoichi Shiraishi,
Gunma University.
Material Classification using Spectral
Reflectance Information. Abdelhameed
Ibrahim and Shoji Tominaga, Chiba
University.
Meta-Heuristics Programming: Memetic
Programming. Emad Hamdy Ahmed and
Masao Fukushima, Kyoto University.
10.15
10.30
S13-1
10.30
10.45
S13-2
10. 45
11.00
S13-3
Abstract
ID
271
009
236
EJISST 2008 June 8~10
From
To
Serial
11.00
11.15
S13-4
11.15
11.30
S13-5
11.30
11.45
S13-6
11.45
12.00
S13-7
12.00
13.00
13.00
13.15
S13-8
13.15
13.30
S13-9
13.30
13.45
S13-10
13.45
14.00
S13-11
14.00
14.15
14.15
14.30
S13-12
14.30
14.45
S13-13
14.45
15.00
S13-14
188
Titles and Authors
Design and Evaluation of Data-Parallel
Algorithms on a Matrix Processor. Ahmed
Sherif Zekri and Stanislav G. Sedukhin,
The University of Aizu.
Cross-Layer Design for Power Efficient
Wireless Ad Hoc Networks. Ghada Khoriba
and Jie Li, Tsukuba University.
Access Point Allocation in Indoor
Environments for Wireless Mesh Networks.
T.H. Farag and and Nobuo FUNABIKI,
Okayama University.
Comparative Study between Three Types of
Down-Conversion Mixers Giving Emphasis
on Sampling Mixer for Wireless
Applications. M. A. ABDELGHANY, R.
K. Pokharel, H. Kanaya and K. Yoshida,
Kyushu University.
Abstract
ID
255
088
119
132
LUNCH
Voice over IP-Networks Performance
Analysis and Enhancement. Ahmed M.
Shawish and Susumu Horiguchi, Tohoku
University.
Router- based Defense against DDoS
Attack. Dalia Nashat and Susumu
Horiguchi, Tohoku University.
Two models for electro-magnetic wave
amplifier utilizing traveling electron beam.
Hesham Fares Ahmed Hassan and Minoru
Yamada, Kanazawa University.
A Dynamic Channel Assignment Problem
for Wireless Internet-access Mesh
Networks. Walaa A. Hassan, Nobuo
Funabiki and Toru Nakanishi, Okayama
University.
133
146
156
163
COFFEE BREAK
Automatic Building of New Field
Association Word Candidates Using Search
Engine. Atlam ELsayed and Jun ichi Aoe,
The University of Tokushima.
Contents Aware Network Security for JPEG
2000 Encoded Images. Ayman Haggag and
Takashi Yahagi, Chiba University.
Towards a novel all-optical switch, design,
fabrication and characterization. Salah A.
Ibrahim and Yoshiaki Nakano, Research
Center for Advanced Science and
Technology, the University of Tokyo.
223
007
037
EJISST 2008 June 8~10
15.00
15.15
S13-15
15.15
15.30
16.00
15.30
15.45
16.30
S13-16
S13-17
189
A method to improve the precision of
search engines using Ranking of Field
Association terms using Co-word analysis.
Mahmoud Rokaya, Elsayed Atlam, Masao
Fuketa, and Jun-ichi Aoe, Tokushima
University.
045
CLOSING CEREMONY
SESSION 14: INFORMATION AND COMMUNICATION
TECHNOLOGY (ICT)
IBUKA CONFERENCE BIG HALL ( FIRST FLOOR)
From
To
Serial
Titles and Authors
Decision Support System for Ubiquitous
Learning Environments. Moushir M. ElBishouty, Hiroaki Ogata and Yoneo Yano,
The University of Tokushima.
Security Analysis of a Crypto-Compression
Algorithm for Medical Images. Osama Ouda
and Yoichi Miyake, Chiba University.
An Intelligent Recommender System Using
Particle Swarm Optimizer (PSO) and Artificial
Immune System (AIS). Amira abdel wahab
ahmed and Shingo Kuroiwa, Chiba University.
An Intelligent Framework for Image
Understanding. Ahmed zaher Mohamed Afifi
and Yoichi MIYAKE, Chiba University.
Participation Enhancement in Urban Planning,
Decision-Making Process Using Virtual
Reality Techniques. Hatem Mahmoud Fathy
and Takafumi Arima, Kyushu University.
Reconstruction algorithms for tomographic
imaging. Essam A. Rashed and Hiroyuki
Kudo, University of Tsukuba.
9.00
9.15
S14-1
9.15
9.30
S14-2
9.30
9.45
S14-3
9.45
10.00
S14-4
10.00
10.15
S14-5
10.15
10.30
S14-6
10.30
10 45
10.45
11.00
S14-7
11.00
11.15
S14-8
11.15
11.30
S14-9
Abstract
ID
190
092
093
094
106
109
BREAK
Load Voltage Regulation and Line Loss
Minimization of Loop Distribution System
Using UPFC. Mahmoud Abdelnaby Sayed
Abdallah, Nagoya Institute of Technology.
Automatic Human Body Modeling for VisionBased Motion Capture. Ibrahim Hemdan and
Kenji Terada, Tokushima University.
Face Recognition under varying illumination
using self-organizing Map. Saleh Aly and RinIchiro Taniguchi, Kyushu University.
115
116
071
EJISST 2008 June 8~10
From
190
To
Serial
Titles and Authors
11.30
11.45
S14-10
11.45
12.00
S14-11
Architecture and Synthesis of a Two-Fingered
Micro-Nano Hybrid Manipulator. Ahmed A.
Ramadan and Tatsuo Arai, Osaka University.
Blind image and video super-resolution based
on mixed-norm. Osam A. Omer and Toshihisa
Tanaka, Tokyo University of Agriculture and
Technology.
12.00
13.00
13.00
13.15
S14-12
13.15
13.30
S14-13
13.30
13.45
S14-14
13.45
14.00
S14-15
14.00
14.15
14.15
14.30
S14-16
14.30
14.45
S14-17
14.45
15.00
S14-18
15.00
15.15
S14-19
15.15
15.30
16.00
15.30
15.45
16.30
S14-20
S14-21
Abstract
ID
269
089
LUNCH
Earthquake Onset Detection using SpectroRatio on Multi-Threshold Time-Frequency
Sub-Band. Ali G. Hafez and T. Kohda,
Kyushu University.
Multiple Object Tracking Using Local PCA.
Ali F. Soliman and K. Terada, Tokushima
University.
A new Algorithm based on Geometric
Analysis for Task Scheduling in
Multiprocessor systems. Hassan Youness,
Masaharu Imai, Abd_Elmonem Wahdan,
Mohammed Moness and Ashraf Salem, Osaka
University.
Computer-Aided Diagnosis System for Liver
Cancer Using Multi Slice CT images. Ahmed
Shawky Mohamed Maklad and Noboru NIKI,
The University of Tokushima.
221
239
244
252
COFFEE BREAK
Video Coding Using Motion Estimation and
Compensation Techniques. Mohamed
Ghoneim, Norimichi Tsumura and Yoichi
Miyake, Chiba University.
Efficient Face Detection and Recognition
System. M. Hassaballah and Shun IDO, Ehime
University.
Automatic Text categorization for Arabic
Documents. Walaa Aly and Seiichi Uchida,
Kyushu University.
A STUDY FOR AUTOMATED VISUAL
INSPECTION OF TEXTILE MATERIALS
BY IMAGE PROCESSING. Khaled Issa and
Hiroshi Nagahashi, Tokyo Institute of
Technology.
CLOSING CEREMONY
256
276
307
293
EJISST 2008 June 8~10
191
SESSION 15 : CIVIL AND ENVIRONMENTAL ENGINEERINGEARTHQUAKE GEOTECHNICAL, AND -AIR POLLUTION
IBUKA CONFERENCE HALL 2 ( THIRD FLOOR)
From
To
Serial
Titles and Authors
DESIGN AND CONSTRUCTION
CHALLENGES OF LONG SPAN
BRIDGES CONCEPT IN EGYPT. Shehata
E. Abdel Raheem and Toshiro Hayashikawa,
Hokkaido University.
High Performance Ferrocement-Grouted
Mortar Composites for Sustainable
Development of Construction Materials.
Mahmoud A. WAFA and Kimio
FUKUZAWA, Ibaraki University.
Innovative Design of Calibration Chamber
for Geotechnical Physical Modeling.
Adel M. El-Kelesh and Ken-ichi Tokida,
Osaka University.
Groundwater seepage into an abandoned
mining site in Egypt. Amgad Salama, T.
Esaki, Kyushu University.
Evaluation of Geo-environmental Impact for
the Application of Industrial Waste
Materials in Geotechnical Problems.
Ahmed A. and Keizo Ugai, Gunma
University.
Geophysical Structures of Several
Geothermal Fields in Egypt and Conceptual,
Numerical Models of Their Geothermal
System. Mohamed Abdel Zaher and Sachio
Ehara, Kyushu University.
9.00
9.15
S15-1
9.15
9.30
S15-2
9.30
9.45
S15-3
9.45
10.00
S15-4
10.00
10.15
S15-5
10.15
10.30
S15-6
10.30
10. 45
10.45
11.00
S15-7
11.00
11.15
S15-8
11.15
11.30
S15-9
Abstract
ID
079
157
177
270
273
059
BREAK
Chemical compounds effect on critical shear
stress and erodability of volcanic ash soil.
Islam Mamdouh Awad and Noriyuki
Yasufuku, Kyushu University.
Numerical Simulation of Debonding Failure
of Reinforced Concrete Beam Strengthened
with Externally Bonded FRP and
Development of Rational Prediction Method.
Khalid Farah and Yasuhiko Sato, Hokkaido
University.
Advanced bifurcation analysis of truss
structures. Manar Ahmed and Kiyohiro
Ikeda, Tohoku University.
063
084
121
EJISST 2008 June 8~10
From
To
Serial
11.30
11.45
S15-10
11.45
12.00
S15-11
12.00
13.00
13.00
13.15
S15-12
13.15
13.30
S15-13
13.30
13.45
S15-14
13.45
14.00
S15-15
14.00
14.15
14.15
14.30
S15-16
14.30
14.45
S15-17
14.45
15.00
S15-18
15.00
15.15
S15-19
192
Titles and Authors
Borehole ground penetrating radar
technique for subsurface fracture
characterization and its application to
geothermal energy extraction. Khamis
Kabeel Ali Mansour and Motoyuki Sato,
Tohoku University.
Evaluation of Crack Elongation
Performance of UHP-SHCC as a Surface
Repairing Material. Ahmed Kamal Abd
Elzaher and Miroru Kunieda, Nagoya
University.
Abstract
ID
134
144
LUNCH
Modifed linear viscoelastic model for
elimination of the tension force in the linear
viscoelastic. Sayed Mahmoud and Hiroshi
Nakazato, Hirosaki University.
SEISMIC ANALYSIS OF CABLESTAYED BRIDGE STEEL TOWERS.
Mohamed OMAR and Toshiro
HAYASHIKAWA, Hokkaido University.
Shear Cracking Behavior in Reinforced
Concrete Members. Hassan M. Zakaria,
Ueda Tamon, Hokkaido University.
Using Ground Penetrating Radar for
Environmental and Archaeological
Investigation in Egypt. Mahmoud Gaballah
and Motoyuki Sato, Tohoku University.
169
197
203
207
COFFEE BREAK
Recoverability of Existing Bridge Columns
under Moderate to Strong Earthquake.
Mohamed Fathy Mohamed Fahmy and
Zhishen Wu, Ibaraki University.
Hydrous peridotite with Ti-rich chromian
spinel "a low-temperature peridotite
overlying slab". Mohamed Zaki Khedr and
Shoji Arai, Kanazawa University.
STUDY OF THE BEHAVIOR OF PILE
GROUPS UNDER LATERAL LOADING.
Mahmoud Nasser Hussien and Susumu Iai,
Kyoto University.
CRACK DETECTION in CONCRETE
STRUCTURES – THEIR
STRENGTHENING USING CFRP.
A.M. ANWAR, Kunio HATTORI and
Hidehiko OGATA, Tottori University.
212
262
275
286
EJISST 2008 June 8~10
From
193
To
Serial
Titles and Authors
15.15
15.30
S15-20
15.30
15.45
S15-21
Inverse CFD Modeling as a Tool to Identify
Pollution Source Locations in Outdoor
Environments: Application of Reversed
Time Marching Method. Mahmoud Bady,
Shinsuke Kato and Hong Huang, University
of Tokyo.
Numerical Predictions of Pollutant
Dispersion near Buildings: Effect of Cell
Geometry. Mohamed M. Hefny and Ooka
Ryozo, The University of Tokyo.
16.00
16.30
Abstract
ID
053
057
CLOSING CEREMONY
SESSION 16 : CIVIL AND ENVIRONMENTAL ENGINEERING -AIR
POLLUTION
IBUKA CONFERENCE HALL 3 ( THIRD FLOOR)
From
To
Serial
9.00
9.15
S16-1
9.15
9.30
S16-2
9.30
9.45
S16-3
9.45
10.00
S16-4
10.00
10.15
S16-5
10.15
10.30
S16-6
Titles and Authors
Analysis on Urban Expansion Issues of
Developing Cities in Egypt. Amany N.
HAREEDY and Atsushi DEGUCHI,
Kyushu University.
Distributed Water Balance Model in
Watershed Coupled With River Flow
Routings. Hassan S. Hemaid and N. Tanaka,
Saitama University.
Preparation of Carbon Coated W18O49 with
Iron and Its Photoactivity under Visible
Light. Hany H. Abdel Ghafar, Tomoki
Tsumura and Masahiro Toyoda, Oita
University.
Observation of Coastal Morphology Using
X-band Radar. Elsayed M. Galal and Satoshi
Takewaka, University of Tsukuba.
Homogenization theory application as upscaling technique for the hydrological
parameters in the arid and semiarid areas,
Wadi Assiut as case study. M. Saber, T.
Hamaguchi and T. Kojiri, Kyoto University.
Laboratory tests on the occurrence of
fluoride rich groundwater of Tono area,
Japan. Abdelrahman M. Abdelgawad and
Kunio Watanabe, Saitama University.
Abstract
ID
246
247
181
211
279
192
EJISST 2008 June 8~10
From
To
Serial
10.30
10.45
S16-7
10. 45
11.00
S16-8
11.00
11.15
194
Titles And Authors
Stiffness Degradation Process during
Liquefaction Applied to the Port Island Site
during the 1995 Hyogo-ken Nambu (Kobe)
Erathquake. Mostafa Thabet Mohammed and
Koichi Nakagawa,
Osaka City University.
“The habitus-Field networking model” an
alternative subcontracting arrangement in
Japan: Evidence from subcontracting clusters
in Higashiosaka district. Tarek Mohamed
Ali, KOBE University.
BREAK
Abstract
ID
036
304
SESSION 17: MECHANICAL ENGINEERING
IBUKA CONFERENCE HALL 3 ( THIRD FLOOR)
From
To
Serial
11.15
11.30
S17-1
11.30
11.45
S17-2
11.45
12.00
S17-3
12.00
13.00
13.00
13.15
S17-4
13.15
13.30
S17-5
13.30
13.45
S17-6
Titles and Authors
Laser Welding of High strength Steel.
Khalid M. Hafez and Seiji Katayama,
Osaka University.
Numerical Simulation of a Hydrogen
Leakage Jet. M. F. El-Amin and H.
Kanayama, Kyushu University.
Modeling of fatigue performance of
structures strengthened with externally
bonded CFRP composites. Hesham M.
Diab and Zhishen Wu, Ibaraki University.
Abstract
ID
193
235
205
LUNCH
Control of Flexible Manipulators Using
Visual Data. Tamer Mohamed Mansour
and Masaru Uchiyama, Tohoku
University.
Design and Simulation of a Tactile Sensor
for Soft-Tissue. Ahmed. M. R. Fath ElBab, Mohamed. E. H. Eltaib, Mohamed.
M. Sallam and Osamu Tabata, Kyoto
University.
Circular Path Estimation of a Rotating
Four-Legged Robot Using a Hybrid
Genetic Algorithm LSM. Abeer
Mahmoud and Tokuji OKADA, Niigata
University.
120
128
201
EJISST 2008 June 8~10
From
To
Serial
13.45
14.00
S17-7
14.00
14.15
14.15
14.30
S17-8
14.30
14.45
S17-9
14.45
15.00
S17-10
15.00
15.15
S17-11
15.15
15.30
S17-12
15.30
15.45
S17-13
16.00
16.30
195
Titles and Authors
Influence of Micro-Bubbles on the Heat
Transfer and Pressure Drop of Water
Flows in A Helical Pipe. Mohammed M.
Shatat and Shinichiro Yanase, Okayama
University.
Abstract
ID
224
COFFEE BREAK
Spray Behavior near the Nozzle of a DISI
Multi-Hole Injector Using Phase Doppler
Anemometer. Fatma Badry Mohamed
Ahmed and Eiji Tomita, Okyama
University.
Transient Spray from Port Fuel Injector.
Mohamed Fathy Cidek Esmail and Eiji
Tomita, Okyama University.
Punching Shear Strength of Concrete Slab
Strengthened with FRP under Various
Environments. Ahmed Sabry Farghaly
and UEDA Tamon, Hokkaido University.
Assuming the Crystallization Age and
Thermal events affected the Basement
Complex, Abu Zenima area West-Central
Sinai, Egypt. Sherif Mansour and Noriko
Hasebe, Kanazawa University.
Fabrication of aluminum nitride coatings
by plasma spraying. Mohammed Shahien,
Motohiro Yamada, Toshiaki Yasui and
Masahiro Fukumoto, Toyohashi
University of Technology (TUT).
On the discrepancies among seismic wave
velocities in soft sediments obtained
using different measuring techniques.
Khaled M. Mamoun and Koichi
Nakagawa, Osaka City University.
CLOSING CEREMONY
251
253
301
061
199
139
EJISST 2008 June 8~10
APPENDIX 3:
PRESENTER
LIST
196
EJISST 2008 June 8~10
Presenter
A. Mounir EL Sayed
A.M. Anwar
197
Technical Session Abstract Page Number
1
15
4
1
40
142
53
38
13
16
114
146
Abeer Abd elRaheem
Ahmed
9
98
Abeer Mahmoud
17
7
150
84
Abou-Hashema M. ElSayed
2
42
Adel Ghoneim
Adel I. Ali
Adel M. El-Kelesh
Ahmed A
Ahmed A. Ramadan
Ahmed Atef El-beih
Ahmed El Basaty
4
8
15
15
14
6
1
47
88
134
135
127
69
37
Ahmed Elkhateeb
4
51
Ahmed Elsayed Goda
Ahmed Hegab
11
11
3
5
15
108
108
45
62
138
10
7
6
13
2
8
107
78
72
117
44
89
7
83
4
50
9
17
99
152
Abd El-Rahman
Abdallah Mahmoud
Makhlof
Abdelhameed Ibrahim
Abdelrahman M.
Abdelgawad
Abeer yassin
Ahmed I. A. Galal
Ahmed Ibrahim Youssef
Ahmed Kamal Abd
Elzaher
Ahmed Kamal Osman
Ahmed M. Abd Rabou
Ahmed M. Hamdan
Ahmed M. Shawish
Ahmed Mohamed Galal
Ahmed Mohamed
Mahmoud
Ahmed Mohamed Nabawy
Ahmed Moustafa Hammad
Ahmed Naeem Atiyya
Ahmed Sabry Farghaly
EJISST 2008 June 8~10
Presenter
198
Technical Session Abstract Page Number
Ahmed Shawky
Mohamed Maklad
14
130
Ahmed Sherif Zekri
Ahmed zaher Mohamed
Afifi
Ahmed. M. R. Fath ElBab
13
14
115
124
17
150
Alaa A. Hussien
Alhosein Hamada Abd-ElAzeem
3
4
45
56
Ali F. Soliman
Ali G. Hafez
Alkhateib Y. Gaafar
14
14
8
7
6
128
128
94
86
74
6
73
16
15
14
144
134
124
4
7
8
5
9
2
6
13
5
6
53
81
93
65
95
43
74
119
63
76
Ayman Haggag
Ayman Samir Farid
Aziz Awaad Aziz
Mohamed
13
9
9
120
96
101
Azza Ebid
4
55
Azza Elgendy
Dalia Hemdan
4
52
4
13
9
54
118
97
Almoamen Abdalla
Amal Ahmed Atwa
Sallam
Amany abdelrehim
bekhit
Amany N. Hareedy
Amgad Salama
Amira abdel wahab
ahmed
Amira M. Hamdan
Amira Said Aly
Amr Mohammed Hassan
Anwar Tawfik Amin Ali
Ashraf A. Ewis
Ashraf Abdel Haleem
Asmaa M. Bayoumi
Atlam ELsayed
Ayman Atiba
Ayman El-Sayed
Dalia Nashat
Doaa Hussein Zineldeen
EJISST 2008 June 8~10
Presenter
Doaa Kirat
199
Technical Session Abstract Page Number
5
6
57
68
13
6
16
13
5
1
14
4
5
120
69
145
115
58
39
125
56
58
Essam Rabea Ibrahim
Mahmoud
1
39
Fathy M. Bayoumi
Fatma Badry Mohamed
Ahmed
1
17
35
151
Gamal M. Dousoky
3
13
5
7
46
116
63
82
Hamdy Saad Mohammed
11
109
Hamed Elgendy
5
6
16
7
15
16
14
14
13
64
77
145
84
139
144
129
125
118
17
7
11
5
149
78
109
66
9
96
Ekhlas Hamed AbdelHafeez
Elmarhomy Ghada
El-Sayed Abdou Khafay
Elsayed M. Galal
Emad Hamdy Ahmed
Eman M. Moustafa
Esam H. Abd-Elhameed
Essam A. Rashed
Essam M. Hamad
Essam Mohamed
Abdelalim
Ghada Khoriba
Gomaa Ahmed
Hala Mahmoud Abd
Elazim
Hanna Hammad
Hany H. Abdel Ghafar
Harb Hassan Kamal
Hassan M. Zakaria
Hassan S. Hemaid
Hassan Youness
Hatem Mahmoud Fathy
Hesham Fares Ahmed
Hassan
Hesham M. Diab
Hiroyuki Akashi
Hosnia Abdel-Mohsein
Hussam Hassan Arafat
Hassan
Hussein Hassan Aly
EJISST 2008 June 8~10
Presenter
Ibrahim Hemdan
Islam Mamdouh Awad
Kamal Elsamman
Khaled Issa
Khaled M. Mamoun
200
Technical Session Abstract Page Number
14
15
12
14
17
8
6
15
8
17
15
126
136
112
132
154
92
71
136
87
148
137
13
17
14
16
2
8
117
148
131
146
42
90
4
49
8
7
15
8
14
92
79
133
90
126
Mahmoud Bady
Mahmoud Elmarhomy
Mahmoud Gaballah
Mahmoud Kandeel
Mahmoud Mohammed
Mahmoud Nasser
Hussien
Mahmoud Ramadan
Mohammed
15
14
15
6
8
15
142
129
140
67
94
141
10
106
Mahmoud Rokaya
13
121
Mahmoud Tanekhy
Amer
Majid Mohamed Safwat
Hafez
9
101
9
98
Manal AM Mahmoud
Manal M. Helmy Nabo
11
10
110
105
Khaled M. Selim
Khalid B. Selim
Khalid Farah
Khalid Ibrahim Sallam
Khalid M. Hafez
Khamis Kabeel Ali
Mansour
M. A. Abdel Ghany
M. F. El-Amin
M. Hassaballah
M. Saber
M.S. Mohamed
Mabrouk A. Abd Eldaim
Maged Fouad
Maged Fouda
Maha Ahmed Khalil
Mahmoud A. Wafa
Mahmoud Abdalla
Mahmoud Abdelnaby
Sayed Abdallah
EJISST 2008 June 8~10
Presenter
201
Technical Session Abstract Page Number
Manar Ahmed
Mohamad M Ahmad
Mohamed A. A. Orabi
15
1
6
137
36
70
Mohamed A. Shebl
4
51
Mohamed Abdel Zaher
Mohamed Abdel-Daim
Mohamed Abdel-Hady
15
10
1
135
102
35
Mohamed Abdelsalam
4
48
Mohamed Ali
Mohamed Fathy Cidek
Esmail
5
17
60
152
Mohamed Fathy
Mohamed Fahmy
Mohamed Ghoneim
Mohamed Hamed
Hussein
15
140
14
10
130
104
Mohamed Helmy
Mohamed M. Hefny
5
15
7
62
143
83
15
1
15
2
7
139
38
141
43
80
Mohammed Ahmed
Abdel Muneem Nouh
10
103
Mohammed Elsayed AbouElhaggag
15
143
Mohammed M. Shatat
Mohammed Saied Abo
Hedaya
17
10
151
107
Mohammed Shahien
Mohammed Yahia Farrag
17
9
8
153
100
91
Mona A. Abo El-Dahb
Montaser Shaykoon
Ahmed
13
6
114
76
Moshira M. Hassan
12
112
Mohamed Momtaz
Mohamed
Mohamed OMAR
Mohamed Reda Berber
Mohamed Zaki Khedr
Mohammad Abdelkareem
Mohammad Ebdel-Rahman
Eshiba
Mohsen Mohammad
Farahat
EJISST 2008 June 8~10
Presenter
202
Technical Session Abstract Page Number
Mostafa Ahmed Sabet
Ahmed Hammam
6
67
Mostafa Ibrahim Attia
Mostafa Thabet
Mohammed
Moushir M. El-Bishouty
10
16
104
147
14
8
123
89
9
5
8
97
65
93
Nasser Mohamed
Abdelwahab Ayoub
2
41
Nevien Kamel Mohamed
Nilly Kamal El-Amir
4
52
7
5
5
2
6
8
14
12
14
6
10
79
61
64
41
75
91
127
111
123
73
103
7
6
1
5
8
13
10
14
6
85
71
36
66
88
121
105
126
70
Sameh Magdeldin
Mohamed
5
57
Sayed Mahmoud
Serag El-Deen Sultan
15
5
138
61
Moustafa Mohamed
Hemida Sarhan
Moustafa sakr
Nabila Osman
Nader ahmed mohmed
darwish
Omar Dessouki
Omar Mostafa Mahmoud
Omar Noureldeen
Omar Sayed Omar
Omneya Abd El Hafez
Osam A. Omer
Osama M.A. Ibrahim
Osama Ouda
Rabab M. Abou El-Magd
Rania Abdel Muneem
Ahmed
Reem Ahmed Saleh
Reyad Elbarbary
S. A. Salman
Safwat A. M. A
Sahar R. Abd El-Hady
Salah A. Ibrahim
Salah M. elSayed
Saleh Aly
Sameh Abdel-Raouf
Ahmed
EJISST 2008 June 8~10
Presenter
Shahenda Abu El-Ela Ali
203
Technical Session Abstract Page Number
4
15
55
133
17
5
153
59
Shymaa Enany
T.H. Farag
5
13
60
116
Taher M. Taha
4
50
Tamer I. Orief
Tamer M. Nasr
Tamer Mohamed
Mansour
Tamer Mohamed Shehata
Tarek M. M. Balabel
Tarek Mohamed Ali
Usama Khaled
10
6
17
106
72
149
6
9
16
1
68
99
147
37
W. H. Abou El Hassan
4
47
Wael A. Abbas
12
111
Wael A. Ahmed
5
4
59
54
4
49
13
14
9
8
119
131
100
87
Waleed Riad Saleh
Walid Mohamed El
Moghazy
11
10
110
102
Yaseen A. Mosa
6
7
75
85
13
7
122
81
7
82
Shehata E. Abdel
Raheem
Sherif Mansour
Sherin Elsayed Shaaban
Wael Mahmoud El-Sayed
Wageh Sobhy AbdElrahem
Walaa A. Hassan
Walaa Aly
Walaa Hassan
Waleed Fathy Khalil
Yasmine Samy Gamal
ElDin
Yasser Mohammad
Yousra Ashraf Mohamed
Anwar
Yuriko Kite