November 25th, 2006 Fisher College of Business Pfizer, Inc. NYSE: PFE Rating: Sell Current Price: $26.89 Target Price (1 Year): $25.15 GICS Sector: Healthcare Sub-Industry: Pharmaceuticals Investment Type: Large-Cap Growth Key Stock Statistics (Sources: Company 10-K, StockVal, Smith Barney) 52-Week Range Trailing 12-Month EPS Trailing 12-Month P/E $10k Invested 5 Yrs. Ago $20.27-$28.60 $1.72 15.8 $7186 Common Shares Outstanding (M) Market Capitalization (B) Institutional Ownership S&P Credit Rating 7210.4 $196.196 66% AAA Dividends/Share Yield Beta $0.96 3.53% 0.61 EPS Estimates Analyst Estimate Consensus Estimate High Low 2005A $1.70 $1.70 $1.70 $1.70 2006E $2.20 $2.02 $2.09 $1.98 2007E $1.53 $2.14 $2.31 $2.01 2008E $1.20 $2.21 $2.43 $1.92 Investment Thesis With over $50 billion in annual revenue, Pfizer is the largest player in the drug industry. Given certain regulatory and market conditions, Pfizer’s business model does not provide for sustainable growth at this level. Most of Pfizer’s revenue, and almost all of its profit, is generated by eight prescription drugs, including the cholesterol-reducing drug Lipitor, the male sexual enhancement pill Viagra, and the hypertension drug Norvasc. Although the demand for prescription drugs is on the rise, pricing pressures and a challenging regulatory environment will limit Pfizer’s profitability. Investment Summary I have assigned Pfizer a one-year price target of $25.15 based on these key assumptions: The aging of America will maintain (and in some cases, increase) the demand for pharmaceuticals through 2030 Democratic control of Congress will put pressure on profit margins for brand-name pharmaceutical companies Democratic control of Congress will restrict major pharmaceutical companies in a variety of ways, including placing restrictions of the timing of advertising, the length of the FDA drug approval process, and the structure of the current drug/compound patent process Healthcare companies will continue to use the massive amounts of cash on their balance sheets to pay out dividends, make acquisitions, and buy back shares of common stock A discounted cash flow (DCF) method of valuation and a comparative multiple valuation both confirm that this stock is, at best, fairly valued and, at worst, 10-20% overvalued Regular dividends will continue to be paid to shareholders, and there will be little change in the payout Technical factors confirm a long-term downtrend in the stock price of Pfizer Price Charts Pfizer Stock Performance (Absolute - $) Pfizer Stock Performance vs. S&P500 Index (%) Table of Contents Cover Sheet …………………………………………………………………………………...…1 Investment Thesis………………………………………………………………………....1 Summary………………………………………………………………………………......1 Table of Contents………………………………………………………………………………...2 Company Overview……………………………………………………………………………...3 Macroeconomic Overview……………………………………………………………………….4 Market Outlook……………………………………………………………………………..........7 Sector Outlook……………………………………………………………………………...........8 Industry Analysis…………………………………………………………………………….....10 Company Analysis……………………………………………………………………………...11 Growth Drivers/Catalysts/Positives/Issues………………………………………………………………11 Risks/Concerns……………………………………...…………………………………...13 Financials....……………………………………………………………………………...16 Valuation……………………………………………………………………………........17 Conclusion……………………………………………………………………………................24 Summary……………………………………………………………………………........24 Recommendation………………………………………………………………………...25 Analyst/Class Information……………………………………………………………………...26 Appendices……………………………………………………………………………...............27 Sources...............................................................................................................................31 Company Overview General From Pfizer’s company website, “Pfizer Inc, founded in 1849, is dedicated to better health and greater access to healthcare for people and their valued animals. Our purpose is helping people live longer, healthier, happier lives. Our route to that purpose is through discovering and developing breakthrough medicines; providing information on prevention, wellness, and treatment; consistent high-quality manufacturing of medicines, consumer products; and global leadership in corporate responsibility. Every day we help 38 million patients, employ more than 100,000 colleagues, utilize the skills of more than 12,000 medical researchers, and work in partnership with governments, individuals, and other payers for healthcare to treat and prevent illnesses— adding both years to life, and life to years.” Pfizer, Inc. is a research-based, global pharmaceutical company headquartered in New York City. It engages in the discovery, development, manufacture, and marketing of prescription medicines for humans and animals, as well as consumer healthcare products worldwide. Founded in 1849 (and later incorporated on June 2nd, 1942), Pfizer operates through three business segments: Human Health, Consumer Healthcare, and Animal Health (StockVal). Segments The Human Health segment offers treatments for cardiovascular and metabolic diseases, central nervous system disorders, arthritis and pain, infectious and respiratory diseases, urogenital conditions, cancer, eye disease, endocrine disorders, and allergies (StockVal). The Consumer Healthcare segment markets various over-the-counter medications for oral care, upper respiratory health, tobacco dependence, gastrointestinal health, skin care, eye care, and hair growth. Its principal products include Listerine mouthwash, Listerine PocketPaks oral care strips, Nicorette for tobacco dependence, Benadryl antihistamine for allergies, Sudafed for sinus congestion, Rogaine for hair growth, Zantac for prevention and relief of heartburn, Rolaids antacid tablets, Neosporin antibiotic ointment, Visine eye drops, Lubriderm moisturizing lotions, and Purell instant hand sanitizer (StockVal). The Animal Health segment develops products for the prevention and treatment of diseases in livestock and companion animals. Its products include parasiticides, anti-inflammatories, vaccines, antibiotics, and related medicines (StockVal). Further, Pfizer manufactures empty soft-gelatin capsules and bulk pharmaceutical chemicals, as well as engages in contract manufacturing. It has collaboration with Nektar Therapeutics, ActivX Biosciences, Inc., TransTech Pharma, Inc., AVANT Immunotherapeutics, Inc., and National Comprehensive Cancer Network (StockVal). Below is a short list of some of the more common drugs that Pfizer sells. Pfizer’s product line is well diversified, with hundreds of drugs currently being sold and hundreds more in the pipeline. Drug Name Lipitor Celebrex Viagra Zoloft Xanax Exubera Zyrtec What It Treats High cholesterol Arthritis Erectile dysfunction Depression Anxiety/Panic Diabetes Allergies Macroeconomic Overview Aging of America From 1900 to 2000, the number of people in the U.S. under the age of 65 has more than tripled. During the same period, the number of people in the U.S. over the age of 65 has increased by a factor of more than eleven. The percentage of elderly (defined by the U.S. Census Bureau as persons over the age of 65) in the United States has jumped from 1 out of 25 people in 1900 to 1 out of 8 people in 1994. Also, declining fertility and mortality rates have led to a staggering increase in the median age of the U.S. population; from 20 years old in 1860 to 34 years old in 1994. Between now and the year 2050, America’s elderly population will more than double, to over 80 million. At that point, the Census Bureau predicts that 1 out of every 5 Americans will be elderly. As shown in Figure 3, most of this growth will happen between 2010 and 2030. This is when the baby-boomers will be entering their retirement and elderly years. Within the elderly age group, the “oldest old” is defined as persons over the age of 85. The “oldest old” is the most rapidly growing segment of the elderly age group. Between 1960 and 1994, the “oldest old” population rose more than 274%. In contrast, the elderly population in general rose 100% and the entire U.S. population grew only 45%. The “oldest old” numbered three million in 1994, making them 10% of the elderly and just over 1% of the total population. In 2050, once the survivors of the baby boom generation become part of the “oldest old”, it is expected that the “oldest old” will number 19 million. At that point, that would make them 24% of elderly Americans and 5% of all Americans. Figure 3 The most common causes of death for the elderly in the United States are heart disease, cancer, and stroke. Of the 2.2 million Americans who died in 1991, 1.6 million were elderly, and 70% died from at least one of the three conditions mentioned above. As seen in Figure 4, the elderly are most concentrated in the Northeast and Midwest, with the exception of Florida, which is the state with the high percentage of elderly population in America. Figure 4 Longevity When the U.S. was founded, the average life expectancy was approximately 35 years. By 1950, it had nearly doubled to 68 years. Since then, it has steadily risen to 76 years in 1991. Recent preliminary data from the National Center for Health Statistics suggests that the average American life expectancy is still increasing. In 2004, it was estimated to be 77.9 years old. According to an article in Science Magazine, the oldest person in all of history was documented to be 122 years old. It is estimated, but also debated, that the maximum life span of a human being is approximately 120 years old. Most scientists theorize that health education, research, and the subsequent medical advances will continue to increase longevity. Eventually, the average American may live to be over 100 years old. Democratic Control of Congress By November 9th, 2006, the Democratic Party had officially gained control of both the United States House of Representatives and the Senate. This shift of political power has multiple implications for the pharmaceutical industry and for brand name drug manufacturers in particular. The pharmaceutical industry is facing a variety of legislation that proposes to cut into profit margins, slow the FDA approval process, shorten patent protection periods, increase the cost of R&D, and increase regulation of product advertising and data disclosure. Figure 6 is a summary of the major legislation that the Democratic Congress will propose during the next few years. Figure 6 Legislation Medicare Reform Drug Importation Prescription Drug User Fee Act Reauthorization Patent Reform Medicaid Reform Drug Safety What it is Would remove a clause that prevents the U.S. government from negotiating directly with drug firms A law allowing patients to get cheap drugs from Canada and other foreign sources The law that lets the drug industry fund the FDA in return for faster drug approvals is up for review Basic reforms will make it more difficult to file multiple patents on a drug Impact Allows the government to negotiate lower brandname drug prices (thus, destroying profit margins) Increased competition on all fronts, the industry may lose face Delays will slow all FDA processes; drug safety and restrictive laws will be attached as riders Deals between big pharmaceutical firms and generic drug companies will be limited The system purchases Many drugs, like ones that drugs for the poor, and it treat schizophrenia, have will be revamped to save nearly all of their market money share amongst the poor Two bipartisan bills aim to Will force the drug make the FDA more industry to disclose more powerful data and do more studies; drugs will carry stronger warnings Adapted from “Six Ways Congress Could Hurt Big Pharma”, by Matthew Herper, from Forbes.com, 11/16/2006 Market Outlook Fundamentals Currently, the overall U.S. stock market looks bullish. Recent Consumer Price Index and Producer Price Index data suggests that inflation is under control, and The Federal Reserve maintains that they will keep interest rates steady for now. Some analysts even predict a decline in interest rates over the next year. Furthermore, company earnings are still growing at a double digit pace, and although the housing market is under pressure, lower oil prices have offset these losses. We are not headed for a recession, as was feared 6 months ago. The United States is currently experiencing a “soft-landing scenario”, in which the economy will gradually begin to grow at a slower pace. Technical Analysis See Figure 7. Technical analysis supports a long-term bullish view of the S&P500. The S&P500 is currently trading near the top of an upward channel. Although in the short-run, this suggests that the markets are due for a correction, the upward bias suggests more upside in the long-run. Also, note that the market broke out of a resistance line around $35, which is also very bullish. Figure 7 S&P 500 COMPOSITE ADJUSTED M-Wtd (SP5A) 54 PRICE 41.45 DATE 11-24-2006 49 StockVal® 44 40 40 36 36 32 32 29 29 26 24 26 24 22 22 20 20 18 18 16 16 14 13 The Ohio State University 14 Fisher College of Business 13 1997 1998 Price Change % 1-Day -0.37 1999 2000 2001 Diff SP5 First Call Data -0.00 Mean Estimate 2002 2003 2004 2005 2006 2007 2008 Data Page # 1 2006 2007 2008 2.60 2.83 3.10 Revenues ($Mil) 72,086 Sector Outlook The Healthcare sector is defensive by nature, but also provides growth opportunities in many areas. Healthcare’s defensive nature means that the sector performs independently of the economic cycle and other economic factors (such as interest rates, housing data, etc.). There are, however, significant external factors that affect the Healthcare sector. Population demographics, government regulation, and product development cycles can affect most of the Healthcare sector. There are two items worth note on the Healthcare sector’s financial statements. The first item can be seen on Figure 8, the Income Statement. Revenues, EPS, and Dividends are consistent and usually increasing. The major reason for some of the income measures not increasing at times is because of significant consolidation (lots of mergers and acquisitions) in the Healthcare Sector. When companies buy other companies, as is common in the Healthcare Sector, financial statements can be skewed for that year due to large charges from the M&A transactions. Figure 8 The second item worth noting can be found on the Healthcare Sector’s Balance Sheet, Figure 9. The Healthcare sector has massive amounts of cash. Almost 19% of this sector’s assets are in cash. This can potentially add significant value to the sector because cash is used for one or more of three things: stock buybacks; dividends to shareholders; or mergers and acquisitions. Each of these three options will increase the value of the company. Figure 9 Overall, the Healthcare sector should outperform the S&P500 over the next year. It is a solid defensive area with some growth potential (particularly in Biotechnology and Generic Drugs). Figure 10 S&P HEALTH CARE SECTOR COMP ADJ M-Wtd (SP-35) 64 PRICE 42.61 DATE 11-24-2006 58 StockVal ® 52 46 46 42 42 38 38 34 34 30 30 26 24 22 26 24 22 20 20 18 18 16 The Ohio State University Fisher College of Business 14 1997 1998 1999 Price Change % Diff SP5 1-Day -0.61 -0.24 1-Week -0.55 -0.64 4-Weeks -2.51 -3.37 QTD -1.17 -6.05 YTD 2.64 -9.59 2005 6.23 3.23 2004 0.41 -8.59 2003 12.90 -13.48 FYE Dec 2005 EPS 2.10 2000 2001 First Call Data Mean Estimate Change High Low Total # Up # Down House Estimate PE Ratio 2002 2003 2004 2005 2006 2.36 +12% 2.42 2.30 20 10 2 2007 2.62 +11% 2.80 2.45 20 7 3 2008 2.91 +11% 3.18 2.62 14 6 2 18.0 16.3 14.6 2006 2007 16 14 2008 Data Page # 1 Revenues ($Mil) Market Value ($Mil) Shares Out (Mil) Volume 60-Day Avg (Th) Volume 60-Day Avg ($M) Dividend Estimate Payout Ratio Retention Rate Dividend Yield 59,729 104,733 2,458.2 13,302 566.7 0.68 29% 71% 1.60% Industry Analysis Pfizer is part of the Major Pharmaceuticals industry, with a focus on researching and developing new drugs and compounds targeted toward humans. Just like the Healthcare Sector, this industry is defensive in nature. Regardless of economic and market conditions, there is a strong demand for pharmaceuticals. In the future, the demand for pharmaceuticals will increase as the elderly population grows and the average life expectancy lengthens. There is growth potential in certain markets where very few or no effective substances/compounds exist to treat conditions. There is also significant growth potential in the market for generic drugs. As patents on big selling drugs expire, generic drug companies can move in and sell the same drugs for much lower prices. Generics One of the main threats to the Major Pharmaceutical industry is the Generic Drug industry. Each year, generic drugs become more important to the Pharmaceutical Industry as a whole. Technically, the Generic Drug industry is considered to be separate from the Major Pharmaceutical industry, but each industry has a significant impact on the other. As patents expire and price competition increases, generic drug companies are becoming more prominent. When patents expire, generic drug companies gain access to massive amounts of market share overnight. R&D At its core, the pharmaceutical industry is driven by research and development. Without new products, a pharmaceutical company cannot sustain itself. Without R&D, a pharmaceutical company cannot find new products. R&D makes up the major expense on major pharmaceutical income statements, and it is a necessity for any firm to survive. Regulation Regulation by the Food and Drug Administration (FDA) is a major part of the product life cycle within the pharmaceutical industry. Drugs can take up to 15 years from the time that they are discovered to the time that they are marketed to consumers. This time is spent testing, evaluating, retesting, and submitting all of the information about the drug to the FDA. Supply and Demand The supply of pharmaceuticals is constantly increasing as new compounds are developed. As patents expire, more companies begin to produce similar versions of the same drug. The demand for pharmaceuticals will increase significantly over the next twenty years, as a massive part of the U.S. population becomes elderly. Overall, people are living longer and disease treatments are becoming better, which prolongs the amount of time each person spends taking certain drugs. Advertising The pharmaceutical industry is known for excessive spending on advertising and promotion. The chart to left shows that a major cost for pharmaceutical companies is product marketing. These figures are from 2001, and have increased since. Company Analysis As seen in Figure 11, Pfizer’s ten-year stock chart is not impressive. It has lost a significant amount of value since the middle of 2000, and has traded up and down since the beginning of 2005. Figure 11 PFIZER INCORPORATED (PFE) 66 PRICE 26.89 DATE 11-24-2006 58 StockVal® 50 44 44 38 34 38 34 29 26 29 26 22 20 22 20 17 17 15 15 13 13 11 10 The Ohio State University 11 Fisher College of Business 10 1997 1998 1999 Price Change % Diff SP5 1-Day -0.77 -0.41 1-Week 0.49 0.40 4-Weeks -1.43 -2.28 QTD -5.18 -10.06 YTD 15.31 3.08 2005 -13.28 -16.28 2004 -23.89 -32.88 2003 15.57 -10.81 FYE Dec 2005 EPS 1.70 2000 2001 First Call Data Mean Estimate Change High Low Total # Up # Down House Estimate PE Ratio 2002 2003 2004 2005 2006 2.02 +19% 2.09 1.98 20 13 2 2007 2.14 +6% 2.31 2.01 20 8 3 2008 2.21 +3% 2.43 1.92 17 9 3 13.3 12.5 12.2 2006 2007 2008 Data Page # 1 Revenues ($Mil) 50,274 Market Value ($Mil) 193,889 Shares Out (Mil) 7,210.4 Volume 60-Day Avg (Th) 31,833 Volume 60-Day Avg ($M) 856.0 Dividend Estimate 0.96 Payout Ratio 47% Retention Rate 53% Dividend Yield 3.57% With a market capitalization of almost $200 billion, Pfizer is the largest pharmaceutical company in the world. There are both positive and negative factors that will affect Pfizer in the future. These will be discussed in the following section. Growth Drivers, Catalysts, Positives Demand As stated previously in the sector and industry analyses, worldwide demand for pharmaceutical products is strong and will continue to increase. As one of the largest pharmaceutical companies in the world, Pfizer has the production capacity to meet this large demand. Pfizer has also demonstrated the ability to manage multiple products with large demand, with sales of over $1 billion for eight different drugs. Acquisitions “Pfizer acquired Warner-Lambert Company (Warner-Lambert) in June 2000. The acquisition was accounted for as a pooling of interests. In accordance with generally accepted accounting principles in the U.S. (GAAP), Pfizer restated all of its consolidated financial statements for periods prior to the acquisition to include the results of operations and financial position of Warner-Lambert as if they had always been merged” (Pfizer 10K, 2005). “Pfizer acquired Pharmacia Corporation (Pharmacia) in April 2003. The acquisition was accounted for as a purchase. In accordance with GAAP, Pfizer did not restate its results of operations and financial position to reflect the historical results of operations and financial position of Pharmacia” (Pfizer 10-K, 2005). “Pfizer acquired Esperion Therapeutics, Inc. (“Esperion”) in February 2004. The acquisition was accounted for as a purchase. Esperion is a biopharmaceutical company focused on the development of high-density lipoprotein (HDL) - targeted (“good cholesterol”) therapies for the treatment of cardiovascular disease” (Pfizer 10-K, 2005). “Pfizer acquired Idun Pharmaceuticals, Inc., a biopharmaceutical company focused on the discovery and development of therapies to control apoptosis (cell death), in April 2005. The acquisition was accounted for as a purchase” (Pfizer 10-K, 2005). “In September 2005, Pfizer acquired Vicuron Pharmaceuticals, Inc., a biopharmaceutical company focused on the development of novel anti-infectives. The acquisition was also accounted for as a purchase” (Pfizer 10-K, 2005). “On February 28, 2006, we completed the acquisition of the sanofi-aventis worldwide rights, including patent rights and production technology, to manufacture and sell Exubera, an inhaled form of insulin for use in adults with type 1 and type 2 diabetes, and the insulin-production business and facilities located in Frankfurt, Germany, previously jointly owned by Pfizer and sanofi-aventis, for approximately $1.4 billion (including transaction costs). In connection with the acquisition, as part of our final purchase price allocation, we recorded an intangible asset for developed technology rights of approximately $1.0 billion, inventory valued at $218 million and goodwill of approximately $166 million, all of which have been allocated to our Pharmaceutical segment. The amortization of the developed technology rights is primarily included in Cost of Sales. Prior to the acquisition, in connection with our collaboration agreement with sanofi-aventis, we recorded a research and development milestone due to us from sanofi-aventis of approximately $118 million ($71 million, after tax) in the first quarter of 2006 in Research and development expenses upon the approval of Exubera in January 2006 by the Food and Drug Administration (FDA)” (Pfizer 10-K, 2005). “On May 16, 2006, Pfizer completed the acquisition of all of the outstanding shares of Rinat Neuroscience Corp., a biologics company with several new central-nervous-system product candidates. In connection with the acquisition, as part of our preliminary purchase price allocation, we recorded $478 million, pre-tax, in Merger-related in-process research and development charges” (Pfizer 10-K, 2005). Divestitures “In June 2006, Pfizer entered into an agreement to sell its Consumer Healthcare business for approximately $16.6 billion in cash. This business comprises substantially all of Pfizer’s former Consumer Healthcare segment and other associated amounts, such as purchase-accounting impacts and merger-related costs, and restructuring and implementation costs. The divestiture of the Consumer Healthcare business is expected to close in late 2006 and is subject to customary closing conditions, including receipt of regulatory approvals” (Pfizer 10-K, 2005). What It Means Demand is the single best factor that Pfizer has going for it. Global demand for pharmaceuticals is constantly increasing. As more drugs are discovered, the drug market expands. With all of the cash that Pfizer has on its balance sheet, the acquisition of promising biotechnology and pharmaceutical companies is an easy way to achieve growth. Below is a list of Pfizer’s most important recent acquisitions. This list also includes the major advantages that each acquisition will bring to Pfizer. Idun Pharmaceuticals o Focus on the discovery and development of therapies to control apoptosis (cell death) Bioren Incorporated o Focus on technology for optimizing antibodies Vicuron Pharmaceuticals o Focus on development of anti-infectives Patent Rights to Exubera o An inhaled for of insulin for adults with type 1 or type 2 diabetes Diabetes is a $12 billion product market Rinat Neuroscience Corporation o Has several new central-nervous-system product candidates Another growth driver for Pfizer is to eliminate less profitable product lines. In June 2006, Pfizer completed the sale of its Consumer Products Division for $16.6 billion in cash to Johnson & Johnson. This division included many big-name, but unprofitable, brands such as Visine, Curell, and Listerine. Pfizer can create growth by putting the proceeds from this sale to more profitable uses. Reinvestment into R&D, stock buybacks, acquisitions, and dividends are all feasible possibilities. Risks, Concerns, Negatives Congress As discussed in the Sector Overview, the recent shift of power in Congress will have significant effects on Pfizer. The biggest problem will be with Medicare. Currently, drug prices are determined by negotiations between the pharmaceutical company and the insurance company. The Democrats propose to allow government interventions in these negotiations in order to create lower drug prices for consumers. This will lead to the erosion of profit margins, which will lead to an overall decrease in the profitability of brand name drug companies. Research and Development Currently, Pfizer spends about $7.5 billion each year for research and development of new drugs. The result of this R&D is that Pfizer is currently working on “235 projects in development, including 152 new molecular entities and 83 product-line extensions” (Pfizer 10-K, 2005). In addition, Pfizer has over 400 projects currently in discovery research, which is the earliest stage of the drug creation process. R&D is one of the largest costs on Pfizer’s income statement. As regulations get tighter and the FDA approval process gets longer, the overall cost of R&D will increase while the profitable life of a drug (the time that it protected by a patent) will decrease. Patent Expiration Drug patents grant biotechnology and pharmaceutical companies the exclusive right to sell the covered drug for a period of 20 years from the date of patent filing. Patents, however, must be applied for before the start of the FDA’s clinical trial process. Since this process can take up to 15 years, the typical effective life of a drug patent is about seven to twelve years. Pfizer’s 2005 10-K directly states, “The expiration of a basic product patent or loss of patent protection resulting from a legal challenge normally results in significant competition from generic products against the originally patented product and can result in a significant reduction in sales of that product in a very short period.” Pfizer has eight “blockbuster” drugs that command sales of over $1 billion per year. As the patents for these “blockbuster” drugs expire, generic drug makers will begin producing equivalents at much cheaper prices. Below is Pfizer’s patent expiration schedule for the next 15 years. Note that the U.S. basic product patent for Zithromax, one of Pfizer’s blockbuster drugs, expired in November of 2005. Figure 12 Drug Zoloft Norvasc Zyrtec Camptosar Aricept Lipitor Xalatan Viagra Detrol Celebrex Lyrica Sutent U.S. Basic Product Patent Expiration Year 2006 2007 2007 2008 2010 2010 2011 2012 2012 2013 2013 2021 For each patent that expires, Pfizer will automatically lose market share to competition. When the patents for blockbuster drugs expire, Pfizer can take significant losses to their revenue and profits. See the quote from Pfizer’s 10-K above. Generic Drugmakers Once a drug patent expires, generic drug companies are free to develop and market generic forms of previously patented drugs. Pioneer drugs, such as Pfizer’s biggest seller Lipitor, can lose up to 70% of their market share overnight with the entry of generic drugs. Generic drug manufacturers such as Teva Pharmaceuticals can price their drugs much cheaper than the brand name pharmaceutical company for three main reasons: 1. They avoid the costs associated with the research and development of the drug 2. They avoid the costs associated with the navigating governmental bureaucracy for getting a drug onto the market as safe and effective (FDA Approval) 3. They avoid almost all of the marketing costs for drugs According to a report by the Tufts Center for the Study of Drug Development, the average total research and development cost, including all of the costs associated with FDA approval, for new drugs in the late 1990’s was $897 million per drug. Generic manufacturers do not incur any of this R&D cost. Also, since generic drug makers typically cannot produce a drug until after it has been on the market for some time, they avoid marketing costs. In fact, most generic drug sales actually benefit from the marketing of the brand name equivalent. Lawsuits An article in the Wall Street Journal says that, since the year 2000, more than 65,000 product liability lawsuits have been filed against prescription drug companies. This is the most in any industry. Pfizer has had to pay out billions of dollars in lawsuit settlements for a variety of claims related to asbestos, defective heart valves, and a number of its brand name drugs. Major lawsuits in the future can cost Pfizer billions of dollars. The uncertainty here is that the FDA testing process for drugs is typically less than 15 years, so no one can be truly sure of what a drug will do to people over a 30-, 40-, or 50-year period. What It Means Pfizer will face significant challenges in the future. At any point in time, Pfizer’s current suite of drug products is constantly decreasing due to patent expiration. Once a patent expires on a drug, Pfizer will typically discontinue the production and sale of it due to immediate unprofitability. Therefore, Pfizer’s research and development department is in a race against time to replace expiring product lines with new, profitable products that have patent protection. In the meantime, the government and the courts are not making this process any easier for Pfizer. Things are getting more complicated and processes are taking longer. The combination of margin erosion, loss of blockbuster drug exclusivity, government regulation, increasing costs, and litigation expenses make Pfizer look much too risky for the prudent investor. Comparatively, generic drug companies look much more attractive as an investment than Pfizer. Generic companies have very few costs related to their products, and they are not regulated as heavily (because their drugs have already passed FDA testing at the original brand name company) as brand name pharmaceutical companies. On top of that, the public supports generic drug manufacturers much more than the brand names because generic drug manufacturers deliver drugs at much lower costs. This is exemplified by Wal-Mart’s recent decision to fill any generic drug prescription for a $4 flat fee. Generic drug makers benefit from all of the positives discussed in this report, while they have limited exposure to the negatives. This chart shows the cost of R&D versus the approvals for new chemical entities (NCEs, or new drugs). R&D spending is increasing exponentially, while new drug approvals are only slightly increasing. Being the largest pharmaceutical firm in the world, Pfizer should feel the effects of this trend. Pfizer will have to spend increasingly large amounts to find new blockbuster drugs that will make up for the cost of their research. Financials Figure 13 shows the financial ratios for Pfizer for the past 5 years (and the expected 2006 ratios). Pfizer implemented a change in accounting principle after 2002, which is why most of the measures drastically decrease between 2002 and 2003. The best comparative data is from 2003 onward. Figure 13 Ratios Items Profitability Gross Margin Net Margin Activity Inventory Turns (using sales) Asset Turns PP&E Turns A/R Turns A/P Turns Cap Ex/Depreciation Credit CA/CL CA (ex CSH)/CL L-T D/A Quick Ratio DuPont EBIT/Sales Sales/Assets E/EBT (1-Tax Rate) Assets/Equity ROE 2005 2006 (Expected) 2001 2002 2003 2004 86.8% 26.8% 87.6% 28.3% 78.6% 8.7% 85.6% 21.6% 83.4% 15.8% 84.5% 31.6% 7.89 7.85 12.06 0.43 0.38 0.70 2.86 2.46 3.01 5.61 5.18 5.58 19.65 17.29 19.93 -1.7068 -0.653168 -0.510701 8.49 0.44 3.00 5.25 23.04 -0.37769 14.84 0.42 2.20 4.25 18.70 -0.375407286 11.68 0.74 2.97 6.05 20.57 -2.16564 1.40 1.32 6.7% 1.22 1.34 1.23 6.8% 1.19 1.28 1.22 4.9% 1.04 1.48 1.41 5.9% 1.23 1.47 1.39 5.4% 1.26 1.56 1.42 5.0% 1.44 34.4% 74.1% 78.0% 214.0% 42.6% 36.4% 69.7% 77.6% 232.4% 45.7% 7.3% 38.3% 120.5% 178.6% 6.0% 26.7% 42.7% 81.1% 180.3% 16.6% 22.5% 43.6% 70.1% 179.1% 12.3% 23.5% 41.7% 134.5% 171.6% 22.6% Pfizer’s gross margin stayed fairly constant, while its net margin increased between 2003 and 2006. Both its net and gross margins are significantly higher than the pharmaceutical industry averages of 65% and 4%, respectively. This is impressive, especially since Pfizer produces so many different products. Pfizer’s high margins are mostly fueled, however, by the sale of its eight blockbuster drugs. Pfizer’s inventory turnover ratio is increasing, suggesting that inventory management is becoming more efficient. This may also mean that costs related to inventory are being controlled. Pfizer’s credit ratios all seem to be increasing, which suggest good credit and liquidity. This is fueled by Pfizer’s massive amounts of cash on the balance sheet. Pfizer’s return on equity has fluctuated from 2003 through 2006, most likely due to a combination of debt taken on, share buybacks, and increasing net margins over the past few years. Valuation Figure 14 StockVal® PFIZER INCORPORATED (PFE) Price 26.89 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 80 HI LO ME CU 60 40 68.0 10.4 28.5 12.4 20 11-22-1996 11-24-2006 0 PRICE / YEAR-FORWARD EARNINGS 16 HI LO ME CU 12 8 12.97 2.92 6.81 3.91 4 11-22-1996 11-24-2006 0 PRICE / SALES 32 HI LO ME CU 24 16 24.4 2.3 11.1 2.9 8 11-22-1996 11-24-2006 0 PRICE / BOOK VALUE 80 HI LO ME CU 60 40 73.9 8.5 29.5 10.4 20 11-22-1996 11-24-2006 0 PRICE / CASH FLOW ADJUSTED At first glance, Figure 14, depicting Pfizer’s Price/Earning Ratio, Price/Sales Ratio, Price/Book Value Ratio, and Price/Cash Flow Ratio on a historical basis, suggests that Pfizer is significantly undervalued relative to past valuation. Mean reversion suggests that, over the long-run, the valuation measures should revert to their longterm average (abbreviated “ME” on the chart). In reality, however, this chart is skewed due to the significant overvaluation and subsequent decline in valuation of Pfizer during the technology bubble and subsequent “bubble pop” from 1997 through 2001. Ten years is too large of a time horizon to comparatively analyze Pfizer. A more relevant measure of valuation is Figure 15, which depicts the same ratios starting from 2003. Figure 15 StockVal® PFIZER INCORPORATED (PFE) Price 26.89 2003 2004 2005 2006 24 HI LO ME CU 20 16 23.1 10.4 15.8 12.4 12 11-22-2002 11-24-2006 8 PRICE / YEAR-FORWARD EARNINGS 8 HI LO ME CU 6 6.73 2.92 4.12 3.91 4 11-22-2002 11-24-2006 2 PRICE / SALES 12 HI LO ME CU 9 6 10.7 2.3 3.2 2.9 3 11-22-2002 11-24-2006 0 PRICE / BOOK VALUE 24 HI LO ME CU 20 16 20.9 8.5 11.8 10.4 12 11-22-2002 11-24-2006 8 PRICE / CASH FLOW ADJUSTED Based on these valuation measures with a shorter time horizon, Pfizer looks much more fairly valued. Pfizer’s forward P/E ratio may suggest a slight undervaluation, but P/E contraction is typical as the organic growth of a company slows. Pfizer’s organic growth, or internal rate of growth based solely on increasing output and enhancing sales, has leveled off during the past 5 years. Pfizer has relied on acquisitions as a main growth driver during this period. Figure 16 shows Pfizer’s valuation relative to the S&P Healthcare sector from 2003 through 2006. This valuation method also suggests that Pfizer is fairly valued relative to its sector. Figure 16 StockVal® PFIZER INCORPORATED (PFE) Price 26.89 2003 2004 2005 2006 1.2 HI LO ME CU 1.0 1.06 0.60 0.85 0.77 0.8 0.6 PRICE / YEAR-FORWARD EARNINGS RELATIVE TO S&P HEALTH CARE SECTOR COMP ADJ (SP-35) M-Wtd 2.7 11-22-2002 11-24-2006 HI LO ME CU 2.4 2.1 2.67 1.53 2.23 2.21 1.8 11-22-2002 11-24-2006 1.5 PRICE / SALES RELATIVE TO S&P HEALTH CARE SECTOR COMP ADJ (SP-35) M-Wtd 2.0 HI LO ME CU 1.6 1.2 1.85 0.58 0.76 0.75 0.8 11-22-2002 11-24-2006 0.4 PRICE / BOOK VALUE RELATIVE TO S&P HEALTH CARE SECTOR COMP ADJ (SP-35) M-Wtd 1.2 HI LO ME CU 1.0 0.8 1.15 0.55 0.77 0.71 0.6 11-22-2002 11-24-2006 0.4 PRICE / CASH FLOW ADJUSTED RELATIVE TO S&P HEALTH CARE SECTOR COMP ADJ (SP-35) M-Wtd Figure 17 depicts the valuation of Pfizer relative to the S&P500 as a whole. From this valuation, Pfizer again looks close to being fairly valued. Figure 17 StockVal® PFIZER INCORPORATED (PFE) Price 26.89 2003 2004 2005 2006 1.4 HI LO ME CU 1.2 1.0 1.37 0.71 1.00 0.86 0.8 11-22-2002 11-24-2006 0.6 PRICE / YEAR-FORWARD EARNINGS RELATIVE TO S&P 500 COMPOSITE ADJUSTED (SP5A) M-Wtd 5 HI LO ME CU 4 3 4.59 1.93 2.84 2.63 2 11-22-2002 11-24-2006 1 PRICE / SALES RELATIVE TO S&P 500 COMPOSITE ADJUSTED (SP5A) M-Wtd 4 HI LO ME CU 3 2 3.71 0.77 1.07 0.99 1 11-22-2002 11-24-2006 0 PRICE / BOOK VALUE RELATIVE TO S&P 500 COMPOSITE ADJUSTED (SP5A) M-Wtd 2.0 HI LO ME CU 1.6 1.2 1.96 0.72 1.00 0.89 0.8 11-22-2002 11-24-2006 0.4 PRICE / CASH FLOW ADJUSTED RELATIVE TO S&P 500 COMPOSITE ADJUSTED (SP5A) M-Wtd Another valuation method is to calculate the per share value of Pfizer by matching a target multiple to a target measure (earnings, sales, book value, EBITDA, or cash flow). Each of these measures is based on a 4 year historical analysis. Pfizer – Absolute Valuation (Figure18) Valuation High Low Mean Measure Price/Forward Earnings Price/Sales Price/Book Price/EBITDA Price/Cash Flow Current Target Multiple 23.1 10.4 15.8 12.4 13.5 Target Measure Per Share $2.20 6.73 10.7 36.5 20.9 2.92 2.3 7.5 8.5 4.12 3.2 11.5 11.8 3.91 2.9 8 10.4 4 3 10 11 $6.97 $9.38 $3.19 $2.05 Target Price $27.88 $28.14 $31.90 $22.55 $29.70 Average: $28.03 The average of these measures suggests a fairly valued price of $28.03 per share. Summary of Relative Valuation Measures – Figure 19 Pfizer – Valuation Relative to the Healthcare Sector Valuation High Low Measure Price/Forward 1.06 0.60 Earnings Price/Sales 2.67 1.53 Price/Book 1.85 0.58 Price/EBITDA 2.05 0.63 Price/Cash Flow 1.15 0.55 Pfizer – Valuation Relative to the S&P500 Valuation High Low Measure Price/Forward 1.37 0.71 Earnings Price/Sales 4.59 1.93 Price/Book 3.71 0.77 Price/EBITDA 4.06 1.02 Price/Cash Flow 1.96 0.72 Mean Current 0.85 0.77 2.23 0.76 0.92 0.77 2.21 0.75 0.69 0.71 Mean Current 1.00 0.86 2.84 1.07 1.36 1.00 2.63 0.99 1.07 0.89 Again, each valuation measure shows that Pfizer is currently relatively in-line with its historical averages, especially when compared to the Healthcare Sector. Technical Analysis Figure 20 PFIZER INCORPORATED (PFE) 66 PRICE 26.89 DATE 11-24-2006 58 StockVal® 50 44 44 38 34 38 34 29 26 29 26 22 20 22 20 17 17 15 15 13 13 11 10 The Ohio State University 11 Fisher College of Business 10 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 Data Page # 1 Price Change % Diff SP5 First Call Data 2006 2007 2008 Pfizer downward channel end of 1998. Pfizer is($Mil) approaching the top 1-Dayhas been trading -0.77 in a -0.41 Mean Estimatesince the2.02 2.14 Currently, 2.21 Revenues 50,274 of the channel. This suggests that in the near term, Pfizer is poised to pull back. In the long term, if the 1-Week trend continues, 0.49 0.40 has Change +3% Market Value ($Mil) 193,889 downward Pfizer even more room+19% to fall. +6% 4-Weeks -1.43 -2.28 High 2.09 2.31 2.43 Shares Out (Mil) 7,210.4 QTD -5.18 -10.06 Low 1.98 2.01 1.92 Volume 60-Day Avg (Th) 31,833 YTD 15.31 3.08 Total 20 20 17 Volume 60-Day Avg ($M) 856.0 2005 -13.28 -16.28 # Up 13 8 9 Dividend Estimate 0.96 2004 -23.89 -32.88 # Down 2 3 3 Payout Ratio 47% 2003 15.57 -10.81 House Estimate Retention Rate 53% FYE Dec 2005 EPS 1.70 PE Ratio 13.3 12.5 12.2 Dividend Yield 3.57% Discounted Cash Flow Model A complete DCF model can be found in Appendix B of this report. Figure 21 shows the sensitivity output of the DCF model for Pfizer. Figure 21 PFE Stock Price Sensitivity Analysis Growth Rate Discount Rate 4% 5% 6% 3% 8% $25.60 $29.25 $35.32 $47.47 9% $21.61 $23.80 $27.10 $32.59 10% $18.77 $20.19 $22.17 $25.15 11% $16.65 $17.61 $18.90 $20.69 12% $15.01 $15.69 $16.56 $17.72 7% $83.93 $43.57 $30.12 $23.39 $19.35 Assumptions: Pfizer will sustain a terminal free cash flow growth rate of 6% per year o Slightly bullish due to Pfizer’s strong cash position and aggressive acquisition strategy The long-term discount rate will be 10% o Industry standard Pfizer’s revenue growth will be flat through 2008 o Management discussed this during the last earnings conference call o Due to a combination of patent expirations Pfizer will not be able to cut costs as quickly and effectively as they would prefer o Management discussed this during the last earnings conference call Aggressive cost cutting will maintain earnings even with flat revenue growth Line of Reasoning: It is a fact that revenue growth is slowing. It is also a fact that, in the pharmaceutical industry, new products are needed to stimulate revenue growth. New products require either massive amounts of expensive R&D or large, costly acquisitions. So, how does a pharmaceutical company significantly cut costs (in the long-run) without taking away from its much needed investment into possible revenue-generating products? It is my belief that Pfizer cannot simply “cut costs” as easily as management makes it sound. Therefore, earnings will be lower for the next couple of years, as shown on my DCF. Summary Figure 22 outlines the key arguments for and against owning PFE: Pro 1. Strong financial statements. Tons of cash on the balance sheet, which allows for acquisitions, share buybacks, and dividends. Pfizer has a sustained free cash flow. 2. Market and sector outlook is positive. The Healthcare Sector is undervalued right now on a variety of measures. 3. Pfizer is a defensive stock with a market cap of about $200 billion. Even if the market moves downward, PFE is not going to lose a significant portion of its value (>50%). 4. Pfizer is the largest pharmaceutical firm in the world. It has the capabilities to attain huge economies of scale and satisfy growing demand for drugs. 5. Lots of drugs in the pipeline. Given the right discoveries and approvals, Pfizer could potentially expand revenues exponentially. 6. Demand for pharmaceuticals is on the rise and will continue rising significantly for the next 40 years. This is mostly due to increasing life spans and the Baby Boomer generation reaching the age of 65. Con 1. A recent binge of acquisitions and the sale of the entire Consumer Products division make it very difficult to forecast the company’s future performance. It is too early to tell how these decisions will effect the company overall. 2. Due to a change in accounting principle, Pfizer’s financial ratios and valuation measures changed significantly after 2002. With only a few years of new data, interpretation and extrapolation is very difficult. 3. Future acquisitions and divestitures are unpredictable and are not always profitable. 4. Patent expirations are destroying Pfizer’s revenue base. Nearly all of Pfizer’s profit can be attributed to its 8 blockbuster drugs. During the next 10 years, Pfizer will lose the patent rights to all of these drugs. 5. Government regulations, especially from Democrats in Congress, seek to destroy Pfizer’s profit margins. 6. Generic competition is constantly stealing market share from Pfizer. 7. R&D is simply that. It does not guarantee that profitable drugs will be discovered. If the new products cannot keep up with the expirations of old products, revenues will deteriorate. 8. Technically, Pfizer is in a long-term downward trend. 9. Current and future litigation settlements could cost Pfizer billions of dollars. 10. Management surprised the world by stating that revenue growth will be flat through 2008. On November 28th, management stated that the blockbuster-potential diabetes drug Exubera is not selling well. What other “surprises” are in store down the road? Recommendation In the present, Pfizer is a strong company on all fronts. Pfizer has great products, strong earnings, and is well diversified. Right now, Pfizer is fairly valued and could even be considered slightly undervalued. Unfortunately, now is not where my concerns lie. My problem with Pfizer happens in the future. I don’t have faith that Pfizer will be able to replenish its deteriorating portfolio of products quickly or efficiently enough to maintain earnings. R&D is becoming more costly, and government regulations will slow everything down. The Democratic win in Congress is a massive blow to Pfizer. Congress is not just anti-big-pharmaceutical, but it is sympathetic towards generic drugs companies and consumers. This make me lose faith in Pfizer’s betterthan-average profit margins. Margins in the pharmaceutical industry are small and contracting because of the factors discusses in this report. The problem for Pfizer is that it can do nothing to prevent any of this. Pfizer’s risk-return trade off is simply not worth the $0.96 annual dividend that it pays. Money invested in Pfizer is better off invested in a generic drug company. Stock Recommendation: Sell the entire holding of PFE Stock Recommendation: Use the proceeds to buy TEVA Sector Recommendation: Overweight the Healthcare Sector by 581 basis points Analyst and Class Information Analyst Name: Analyst Email: Analyst Phone Number: Lee Wallingford Wallingford.12@osu.edu 513-225-2029 University: College: Class Name: Advisor: Date: The Ohio State University Fisher College of Business Bus-Fin 724 Royce A. West, CFA Updated November 28th, 2006 Appendix A – Pfizer Financial Statements Appendix B – DCF Model for Pfizer Terminal Discount Rate = Terminal FCF Growth = Year Revenue % Growth Operating Income Operating Margin Taxes Tax Rate Net Income % Growth Forecast 2007E 2008E 2006E 50,498 0.00% 50,498 0.00% 50,498 0.00% Terminal Value 2009E 54,033 7.00% 11,851.1 14,422.3 11,897.0 17,074.3 23.47% 28.56% 23.56% 31.60% 3,534.8 29.8% 10.0% 6.0% 2010E 2011E 57,815 7.00% 61,862 7.00% 2012E 2013E 2014E 66,192 7.00% 70,826 7.00% 18,269.5 19,548.4 20,916.8 31.60% 31.60% 31.60% 22,380.9 31.60% 3,534.8 30.0% 3,534.8 30.0% 5,122.3 30.0% 5,480.9 30.0% 5,864.5 30.0% 6,275.0 30.0% 6,714.3 30.0% 15,936.3 10,887.4 7.00% -31.68% 8,362.1 -23.19% 8,947.5 7.00% 9,573.8 10,244.0 10,961.0 7.00% 7.00% 7.00% 11,728.3 7.00% Add Depreciation/Amort % of Sales % of Capex 5,966.3 11.8% 266.4% 6,384.0 12.6% 285.0% 6,830.8 13.5% 304.9% 3,900.0 7.2% 154.1% 4,134.0 7.2% 144.5% Plus/(minus) Changes WC % of Sales 1,004.0 -2.0% (880.0) (942.0) (864.5) -1.6% (925.0) -1.6% Subtract Cap Ex Capex % of sales 2,240.0 4.4% 2,240.0 4.4% 2,240.0 4.4% 2,531.2 4.7% 2,860.3 4.9% 3,652.3 5.5% 4,127.1 5.8% 14,151.4 12,011.0 -31.5% -15.1% 9,451.8 -21.3% 9,922.5 10,404.1 10,894.7 5.0% 4.9% 4.7% 11,391.7 4.6% Free Cash Flow YOY growth NPV of free cash flows NPV of terminal value Projected Equity Value Free Cash Flow Yield 20,666.6 N/A $78,723.21 $104,640.59 $183,363.80 11.3% 4,382.0 7.1% 135.6% 4,645.0 7.0% 127.2% 4,923.7 7.0% 119.3% (989.8) (1,059.1) -1.6% -1.6% (1,133.2) -1.6% 3,232.1 5.2% 42.9% 57.1% Implied equity value/share Upside/(Downside) to DCF 27.21 $25.15 -7.6% 81,088 7.00% 23,947.6 25,623.9 31.60% 31.60% 7,184.3 30.0% 7,687.2 30.0% 12,549.3 13,427.7 7.00% 7.00% 5,219.1 6.9% 111.9% 5,532.2 6.8% 105.0% (1,212.5) (1,297.4) -1.6% -1.6% 4,663.6 6.2% 5,269.8 6.5% 11,892.3 12,392.7 4.4% 4.2% 78,315 7290 Cash/Op's % of Sales Current Price 75,784 7.00% Terminal P/E EV/EBITDA Free Cash Yield '06-10 Cash/Op's Shares Outstanding 2015E 29.7% 328,407.0 24.5 10.3 3.77% Sources AARP.com Website http://www.aarp.org/bulletin/medicare/Articles/0310_sidebar_2.html Forbes.com Website “Six Ways Congress Could Hurt Big Pharma”, by Matthew Herper 11/16/2006 Pfizer 10-K, 2005 Pfizer 10-Q, September 2006 Pfizer Company Website Website http://mediaroom.pfizer.com/index.php?s=company_overview Science Magazine Online Website http://www.sciencemag.org/cgi/content/full/309/5731/83 http://www.sciencemag.org/cgi/content/full/303/5665/1796/F2 StockVal U.S. Census Bureau Website http://www.census.gov/population/socdemo/statbriefs/agebrief.html U.S. Food and Drug Administration Website http://www.fda.gov/cder/ob/faqs.htm